LOCUS       DAVMBH010000001       122530 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVMBH010000001 DAVMBH010000000
VERSION     DAVMBH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 122530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 122530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..122530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.001"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            543..1387
                     /locus_tag="VYP30_000001"
                     /pseudo
     CDS             543..1387
                     /locus_tag="VYP30_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            1673..1906
                     /locus_tag="VYP30_000002"
     CDS             1673..1906
                     /locus_tag="VYP30_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807072.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            1928..2605
                     /locus_tag="VYP30_000003"
     CDS             1928..2605
                     /locus_tag="VYP30_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807073.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            2617..3282
                     /locus_tag="VYP30_000004"
     CDS             2617..3282
                     /locus_tag="VYP30_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807074.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            3354..4580
                     /locus_tag="VYP30_000005"
     CDS             3354..4580
                     /locus_tag="VYP30_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1807075.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(4932..5009)
                     /locus_tag="VYP30_000006"
                     /pseudo
     CDS             complement(4932..5009)
                     /locus_tag="VYP30_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5080..5736
                     /locus_tag="VYP30_000007"
     CDS             5080..5736
                     /locus_tag="VYP30_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1807076.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTVLGDLLPNSEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            5726..6049
                     /locus_tag="VYP30_000008"
     CDS             5726..6049
                     /locus_tag="VYP30_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1807077.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            6153..6983
                     /locus_tag="VYP30_000009"
     CDS             6153..6983
                     /locus_tag="VYP30_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1807078.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            7137..7991
                     /locus_tag="VYP30_000010"
     CDS             7137..7991
                     /locus_tag="VYP30_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1807079.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLKNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAIPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEETS
                     DGLDQPVW"
     gene            8091..9464
                     /locus_tag="VYP30_000011"
     CDS             8091..9464
                     /locus_tag="VYP30_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1807080.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREIALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            9457..10518
                     /locus_tag="VYP30_000012"
     CDS             9457..10518
                     /locus_tag="VYP30_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1807081.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            10520..11212
                     /locus_tag="VYP30_000013"
     CDS             10520..11212
                     /locus_tag="VYP30_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807082.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQS
                     LGDFLTKKLSHK"
     gene            complement(11242..11811)
                     /locus_tag="VYP30_000014"
     CDS             complement(11242..11811)
                     /locus_tag="VYP30_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1807083.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            11946..12560
                     /locus_tag="VYP30_000015"
     CDS             11946..12560
                     /locus_tag="VYP30_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1807084.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFTLSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            12562..14208
                     /locus_tag="VYP30_000016"
     CDS             12562..14208
                     /locus_tag="VYP30_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1807085.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            14220..15506
                     /locus_tag="VYP30_000017"
     CDS             14220..15506
                     /locus_tag="VYP30_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1807086.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            15558..16091
                     /locus_tag="VYP30_000018"
     CDS             15558..16091
                     /locus_tag="VYP30_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807087.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            16169..16639
                     /gene="nrdI"
                     /locus_tag="VYP30_000019"
     CDS             16169..16639
                     /gene="nrdI"
                     /locus_tag="VYP30_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1807088.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(16932..18194)
                     /locus_tag="VYP30_000020"
     CDS             complement(16932..18194)
                     /locus_tag="VYP30_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1807089.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(18504..18962)
                     /locus_tag="VYP30_000021"
     CDS             complement(18504..18962)
                     /locus_tag="VYP30_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1807090.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(18959..19399)
                     /locus_tag="VYP30_000022"
     CDS             complement(18959..19399)
                     /locus_tag="VYP30_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1807091.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFVQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            19605..21554
                     /gene="mutL"
                     /locus_tag="VYP30_000023"
     CDS             19605..21554
                     /gene="mutL"
                     /locus_tag="VYP30_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1807092.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(21879..22346)
                     /locus_tag="VYP30_000024"
     CDS             complement(21879..22346)
                     /locus_tag="VYP30_000024"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1807093.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(22347..23552)
                     /locus_tag="VYP30_000025"
     CDS             complement(22347..23552)
                     /locus_tag="VYP30_000025"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1807094.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRIHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(23572..24207)
                     /gene="ribE"
                     /locus_tag="VYP30_000026"
     CDS             complement(23572..24207)
                     /gene="ribE"
                     /locus_tag="VYP30_000026"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1807095.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(24192..25292)
                     /gene="ribD"
                     /locus_tag="VYP30_000027"
     CDS             complement(24192..25292)
                     /gene="ribD"
                     /locus_tag="VYP30_000027"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1807096.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(25427..25541)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            25698..26291
                     /gene="ruvA"
                     /locus_tag="VYP30_000028"
     CDS             25698..26291
                     /gene="ruvA"
                     /locus_tag="VYP30_000028"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1807097.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            26301..26864
                     /locus_tag="VYP30_000029"
     CDS             26301..26864
                     /locus_tag="VYP30_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1807098.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            26861..27538
                     /locus_tag="VYP30_000030"
     CDS             26861..27538
                     /locus_tag="VYP30_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807099.1"
                     /translation="MMSNKNKEILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(27675..28706)
                     /locus_tag="VYP30_000031"
     CDS             complement(27675..28706)
                     /locus_tag="VYP30_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1807100.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKSEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(28961..29644)
                     /locus_tag="VYP30_000032"
     CDS             complement(28961..29644)
                     /locus_tag="VYP30_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1807101.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(29656..30600)
                     /locus_tag="VYP30_000033"
     CDS             complement(29656..30600)
                     /locus_tag="VYP30_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1807102.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(30756..31922)
                     /locus_tag="VYP30_000034"
     CDS             complement(30756..31922)
                     /locus_tag="VYP30_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1807103.1"
                     /translation="MKITEVIKKDGSKVYRANIYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKATQEKIAFQKAGSTRQKASTIKNYQELANLWLESYKNTVKPNTQDNVRKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKGAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDSDRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHVTKTLNRDLEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRESVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(32304..32963)
                     /locus_tag="VYP30_000035"
     CDS             complement(32304..32963)
                     /locus_tag="VYP30_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807104.1"
                     /translation="MLINRLAILLAERSMSGARLASDTGIAQSTISKITSNKSKQVDY
                     ETVNKICNTLGVTSDDFFDYSPIDYEIKYFIDEDSGDIFTFIKILDRDRPVATLEYKV
                     DLEFHINTNKPDNLVGIEEIKRNYQQVEIITVKVCLKKQNKETYDKFTKLPSNFQNIF
                     TNDLLQVVGKNIKEYLIQEFKEEFVFAKNSSGHVDQLLSEDIQIIVSSKIVDCKFELP
                     F"
     gene            33124..33327
                     /locus_tag="VYP30_000036"
     CDS             33124..33327
                     /locus_tag="VYP30_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807105.1"
                     /translation="MLKNNLLIVFAEKKTNASKVSNETGIAESTISNLTNNKTDVKLS
                     TLIKLCNALKVRLSDLIEFSPEN"
     gene            33342..33971
                     /locus_tag="VYP30_000037"
     CDS             33342..33971
                     /locus_tag="VYP30_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV1807106.1"
                     /translation="MELVYMDGKKEPYTTSEIIAECAGVTHHTIQELLRKHKADFESY
                     GIIAFEMRKLDGRGRPMKIYRLNEQQATLLITYLKNTEPVRRFKMNLVKAFFEMREEL
                     SKFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDRNAKQLREERGGY
                     NGIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            34406..34858
                     /locus_tag="VYP30_000038"
     CDS             34406..34858
                     /locus_tag="VYP30_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807107.1"
                     /translation="MEETAYENLTRRIDRISAEMREIGEKTGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSYKIEAVSKSTTGMFFHPGIFEMDAMRQAFFKRQAMHFFENEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            34855..35055
                     /locus_tag="VYP30_000039"
     CDS             34855..35055
                     /locus_tag="VYP30_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807108.1"
                     /translation="MTLDLDNMTQAEFDKQMAEIKERNPNLFQFIADFVDRKVTPKEV
                     DEFLKMGRSDQVDYIKNYKARA"
     gene            35057..35272
                     /locus_tag="VYP30_000040"
     CDS             35057..35272
                     /locus_tag="VYP30_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807109.1"
                     /translation="MNELDLTNTQAVISMVVLIGLLLYLNHRDRKKSAQFERENQQTI
                     ETPSEDLSPDYGRYIQLAGVRVYGGMK"
     gene            35269..35562
                     /locus_tag="VYP30_000041"
     CDS             35269..35562
                     /locus_tag="VYP30_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807110.1"
                     /translation="MSYTMNLYPDIEKISDETYFTREIFLATCLNNTIRIAVARGVLT
                     SQLLDKETKEVVCKTLDTIIENQKAILQGVASGQITFLNKSKEEEELNESIRE"
     gene            35543..35884
                     /locus_tag="VYP30_000042"
     CDS             35543..35884
                     /locus_tag="VYP30_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1807111.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LIMRYGIPIIGVRHGTFRGYFIPANKEELLDGAKTFYNQIREEEKRLTVLLNADLESY
                     KQLLKGADEYV"
     gene            35877..36158
                     /locus_tag="VYP30_000043"
     CDS             35877..36158
                     /locus_tag="VYP30_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1807112.1"
                     /translation="MFSLSQESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     GELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            36293..37153
                     /locus_tag="VYP30_000044"
     CDS             36293..37153
                     /locus_tag="VYP30_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV1807113.1"
                     /translation="MAIYEAKGFQSNLVYPFDKIEPFQYIELFKPLVVPEGANIEEFK
                     RTQAPYCISGKVTPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSTLFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            37197..38675
                     /locus_tag="VYP30_000045"
     CDS             37197..38675
                     /locus_tag="VYP30_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV1807114.1"
                     /translation="MEVREQEHPPRTMKELENRIFKAGEEWRAEHTETKVNETTGDVT
                     EKVAIPQTFTVAKILSEIVTFTFISKSNIADYSLLYIYDLDEGIYTASNDLFNLLCKT
                     FDVRIKPREWPQIKLMVRTLTKIRKPLESSNLIPVQNGIINLETKELFPFSPKYVITS
                     KISTAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINSNHTRNKFAI
                     FYGDGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYL
                     KNPSDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVP
                     FNADFNGEKEKPWIKNEFLANDEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEEN
                     DYLLSWVKHEYMERGWHELDVVPVFILTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQ
                     LTPNRYSLRKKRVPSEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            39026..39193
                     /locus_tag="VYP30_000046"
     CDS             39026..39193
                     /locus_tag="VYP30_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807115.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEINDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            39276..39806
                     /locus_tag="VYP30_000047"
     CDS             39276..39806
                     /locus_tag="VYP30_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807116.1"
                     /translation="MTLKTFSDKAKTFTFTYEFKDLDTAMVAGHALLGYMTGTYEVPS
                     ISITHKDKGTLVAEYVEDHKLNKTFKRICDSFKDYYNQPVDDEAFEERYKRERVLQLK
                     ESEDFENLLEKVTDYELELLDYADRLLSDKPIPMDSMTAFGTLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            39877..40380
                     /locus_tag="VYP30_000048"
     CDS             39877..40380
                     /locus_tag="VYP30_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807117.1"
                     /translation="MKRLAIETITKPMKLRGISKGIAELDGQRLEIDLDNLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKSTLNRSKTNCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKRDRYHKHYKKFLKYTKKGDRF
                     WLNGLRL"
     gene            41978..42334
                     /locus_tag="VYP30_000049"
     CDS             41978..42334
                     /locus_tag="VYP30_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1807118.1"
                     /translation="MQLKYQSLESGLLAGSSQFQTRVSTSKTNTAENKLLDTLELRDK
                     IAEQIQAIINERMEAMDMINQLEEIEEWLVLVMIYFNNLPMVKICNDLNFSKVQIYRI
                     RKKAIENLAKVKNANR"
     gene            42321..42659
                     /locus_tag="VYP30_000050"
     CDS             42321..42659
                     /locus_tag="VYP30_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001121035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807119.1"
                     /translation="MPIDKEETIKQAYKFLKSYHSLVKLSLGGQDGAFEAKAMELLRV
                     IEAFRDNLDDVRHEIFANLFTRRTGERLKLWQIYEALDIDKAEYERLKAEILLDFTKS
                     YCGGVLLKKC"
     gene            43313..46144
                     /gene="uvrA"
                     /locus_tag="VYP30_000051"
     CDS             43313..46144
                     /gene="uvrA"
                     /locus_tag="VYP30_000051"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1807120.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKIQKDGYVRVRVDGEVYDVTEVLELSKSRQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            46137..47198
                     /locus_tag="VYP30_000052"
     CDS             46137..47198
                     /locus_tag="VYP30_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1807121.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASSLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            47330..47728
                     /gene="spx"
                     /locus_tag="VYP30_000053"
     CDS             47330..47728
                     /gene="spx"
                     /locus_tag="VYP30_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1807122.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            47794..48363
                     /locus_tag="VYP30_000054"
     CDS             47794..48363
                     /locus_tag="VYP30_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1807123.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGFENLLKNEPSKYISDRLANGATEQ"
     gene            48450..48716
                     /locus_tag="VYP30_000055"
     CDS             48450..48716
                     /locus_tag="VYP30_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1807124.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            48720..49139
                     /gene="ruvX"
                     /locus_tag="VYP30_000056"
     CDS             48720..49139
                     /gene="ruvX"
                     /locus_tag="VYP30_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1807125.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            49155..49460
                     /locus_tag="VYP30_000057"
     CDS             49155..49460
                     /locus_tag="VYP30_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1807126.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            49668..50918
                     /locus_tag="VYP30_000058"
     CDS             49668..50918
                     /locus_tag="VYP30_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1807127.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLACQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMRERKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLAEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            50915..51457
                     /locus_tag="VYP30_000059"
     CDS             50915..51457
                     /locus_tag="VYP30_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1807128.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTLDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            51603..53135
                     /gene="cls"
                     /locus_tag="VYP30_000060"
     CDS             51603..53135
                     /gene="cls"
                     /locus_tag="VYP30_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1807129.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            53213..53356
                     /locus_tag="VYP30_000061"
     CDS             53213..53356
                     /locus_tag="VYP30_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807130.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            53393..54931
                     /locus_tag="VYP30_000062"
     CDS             53393..54931
                     /locus_tag="VYP30_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1807131.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSNYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            55051..57258
                     /gene="nrdD"
                     /locus_tag="VYP30_000063"
     CDS             55051..57258
                     /gene="nrdD"
                     /locus_tag="VYP30_000063"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1807132.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSNQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            57270..57410
                     /locus_tag="VYP30_000064"
     CDS             57270..57410
                     /locus_tag="VYP30_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807133.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            57454..57960
                     /locus_tag="VYP30_000065"
     CDS             57454..57960
                     /locus_tag="VYP30_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807134.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAAILANGGIFEDARNGVER
                     YWIEVANE"
     gene            57953..58543
                     /gene="nrdG"
                     /locus_tag="VYP30_000066"
     CDS             57953..58543
                     /gene="nrdG"
                     /locus_tag="VYP30_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1807135.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            58540..59156
                     /locus_tag="VYP30_000067"
                     /pseudo
     CDS             58540..59156
                     /locus_tag="VYP30_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            59417..59725
                     /gene="rpsJ"
                     /locus_tag="VYP30_000068"
     CDS             59417..59725
                     /gene="rpsJ"
                     /locus_tag="VYP30_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1807136.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            59941..60567
                     /gene="rplC"
                     /locus_tag="VYP30_000069"
     CDS             59941..60567
                     /gene="rplC"
                     /locus_tag="VYP30_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1807137.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            60592..61215
                     /gene="rplD"
                     /locus_tag="VYP30_000070"
     CDS             60592..61215
                     /gene="rplD"
                     /locus_tag="VYP30_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1807138.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            61215..61511
                     /locus_tag="VYP30_000071"
     CDS             61215..61511
                     /locus_tag="VYP30_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1807139.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            61529..62362
                     /gene="rplB"
                     /locus_tag="VYP30_000072"
     CDS             61529..62362
                     /gene="rplB"
                     /locus_tag="VYP30_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1807140.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            62466..62747
                     /gene="rpsS"
                     /locus_tag="VYP30_000073"
     CDS             62466..62747
                     /gene="rpsS"
                     /locus_tag="VYP30_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1807141.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            62759..63103
                     /gene="rplV"
                     /locus_tag="VYP30_000074"
     CDS             62759..63103
                     /gene="rplV"
                     /locus_tag="VYP30_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1807142.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            63116..63769
                     /gene="rpsC"
                     /locus_tag="VYP30_000075"
     CDS             63116..63769
                     /gene="rpsC"
                     /locus_tag="VYP30_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1807143.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            63773..64186
                     /gene="rplP"
                     /locus_tag="VYP30_000076"
     CDS             63773..64186
                     /gene="rplP"
                     /locus_tag="VYP30_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1807144.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            64196..64402
                     /locus_tag="VYP30_000077"
     CDS             64196..64402
                     /locus_tag="VYP30_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1807145.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            64427..64687
                     /gene="rpsQ"
                     /locus_tag="VYP30_000078"
     CDS             64427..64687
                     /gene="rpsQ"
                     /locus_tag="VYP30_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1807146.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            64713..65081
                     /gene="rplN"
                     /locus_tag="VYP30_000079"
     CDS             64713..65081
                     /gene="rplN"
                     /locus_tag="VYP30_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1807147.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            65159..65464
                     /gene="rplX"
                     /locus_tag="VYP30_000080"
     CDS             65159..65464
                     /gene="rplX"
                     /locus_tag="VYP30_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1807148.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            65488..66030
                     /gene="rplE"
                     /locus_tag="VYP30_000081"
     CDS             65488..66030
                     /gene="rplE"
                     /locus_tag="VYP30_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1807149.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            66048..66317
                     /gene="rpsN"
                     /locus_tag="VYP30_000082"
     CDS             66048..66317
                     /gene="rpsN"
                     /locus_tag="VYP30_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1807150.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            66602..67000
                     /gene="rpsH"
                     /locus_tag="VYP30_000083"
     CDS             66602..67000
                     /gene="rpsH"
                     /locus_tag="VYP30_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1807151.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            67192..67728
                     /gene="rplF"
                     /locus_tag="VYP30_000084"
     CDS             67192..67728
                     /gene="rplF"
                     /locus_tag="VYP30_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1807152.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            67812..68168
                     /gene="rplR"
                     /locus_tag="VYP30_000085"
     CDS             67812..68168
                     /gene="rplR"
                     /locus_tag="VYP30_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1807153.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            68186..68680
                     /gene="rpsE"
                     /locus_tag="VYP30_000086"
     CDS             68186..68680
                     /gene="rpsE"
                     /locus_tag="VYP30_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1807154.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            68652..68876
                     /gene="rpmD"
                     /locus_tag="VYP30_000087"
     CDS             68652..68876
                     /gene="rpmD"
                     /locus_tag="VYP30_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1807155.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            69021..69461
                     /gene="rplO"
                     /locus_tag="VYP30_000088"
     CDS             69021..69461
                     /gene="rplO"
                     /locus_tag="VYP30_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1807156.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            69474..70784
                     /gene="secY"
                     /locus_tag="VYP30_000089"
     CDS             69474..70784
                     /gene="secY"
                     /locus_tag="VYP30_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1807157.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            70935..71573
                     /locus_tag="VYP30_000090"
     CDS             70935..71573
                     /locus_tag="VYP30_000090"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1807158.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNSDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            71690..71908
                     /gene="infA"
                     /locus_tag="VYP30_000091"
     CDS             71690..71908
                     /gene="infA"
                     /locus_tag="VYP30_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1807159.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            71933..72049
                     /gene="rpmJ"
                     /locus_tag="VYP30_000092"
     CDS             71933..72049
                     /gene="rpmJ"
                     /locus_tag="VYP30_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1807160.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            72067..72432
                     /gene="rpsM"
                     /locus_tag="VYP30_000093"
     CDS             72067..72432
                     /gene="rpsM"
                     /locus_tag="VYP30_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1807161.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            72450..72833
                     /gene="rpsK"
                     /locus_tag="VYP30_000094"
     CDS             72450..72833
                     /gene="rpsK"
                     /locus_tag="VYP30_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1807162.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            72876..73811
                     /locus_tag="VYP30_000095"
     CDS             72876..73811
                     /locus_tag="VYP30_000095"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1807163.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            73823..74209
                     /gene="rplQ"
                     /locus_tag="VYP30_000096"
     CDS             73823..74209
                     /gene="rplQ"
                     /locus_tag="VYP30_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1807164.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            74474..74740
                     /locus_tag="VYP30_000097"
     CDS             74474..74740
                     /locus_tag="VYP30_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1807165.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            74750..76087
                     /locus_tag="VYP30_000098"
     CDS             74750..76087
                     /locus_tag="VYP30_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1807166.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            76331..77023
                     /locus_tag="VYP30_000099"
     CDS             76331..77023
                     /locus_tag="VYP30_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1807167.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(77126..78771)
                     /locus_tag="VYP30_000100"
                     /pseudo
     CDS             complement(77126..78771)
                     /locus_tag="VYP30_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(78761..79852)
                     /locus_tag="VYP30_000101"
     CDS             complement(78761..79852)
                     /locus_tag="VYP30_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807168.1"
                     /translation="MSEIEIINAKKIYHDVSVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNLSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(79865..80986)
                     /locus_tag="VYP30_000102"
                     /pseudo
     CDS             complement(79865..80986)
                     /locus_tag="VYP30_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(81203..81400)
                     /locus_tag="VYP30_000103"
     CDS             complement(81203..81400)
                     /locus_tag="VYP30_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1807169.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(81475..82251)
                     /locus_tag="VYP30_000104"
     CDS             complement(81475..82251)
                     /locus_tag="VYP30_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1807170.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            82373..83119
                     /locus_tag="VYP30_000105"
     CDS             82373..83119
                     /locus_tag="VYP30_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1807171.1"
                     /translation="MKRLEQIIKLVSEHEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            83132..84112
                     /locus_tag="VYP30_000106"
     CDS             83132..84112
                     /locus_tag="VYP30_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1807172.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            84307..84627
                     /locus_tag="VYP30_000107"
     CDS             84307..84627
                     /locus_tag="VYP30_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1807173.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            84673..84981
                     /locus_tag="VYP30_000108"
     CDS             84673..84981
                     /locus_tag="VYP30_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1807174.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            84998..86296
                     /locus_tag="VYP30_000109"
     CDS             84998..86296
                     /locus_tag="VYP30_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1807175.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            86447..88885
                     /locus_tag="VYP30_000110"
     CDS             86447..88885
                     /locus_tag="VYP30_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1807176.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            88904..89572
                     /locus_tag="VYP30_000111"
     CDS             88904..89572
                     /locus_tag="VYP30_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1807177.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            89590..90678
                     /locus_tag="VYP30_000112"
     CDS             89590..90678
                     /locus_tag="VYP30_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1807178.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            91145..93646
                     /locus_tag="VYP30_000113"
     CDS             91145..93646
                     /locus_tag="VYP30_000113"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1807179.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEEA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTRADGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKSVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFVQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKIMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIVVPNKLVNIVVK"
     gene            93840..94535
                     /locus_tag="VYP30_000114"
     CDS             93840..94535
                     /locus_tag="VYP30_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807180.1"
                     /translation="MPVNEYGQMIGESMEAYTPGELPSFDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVANLEELVTLLNQMLARKDRFYYAIIDKATGKALG
                     TLSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFDELNYRRYEWKCDAL
                     NLPSRRAAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDKDWPKVKSRLEIWLRPENF
                     DKNGQQYKSLREF"
     gene            94547..94963
                     /locus_tag="VYP30_000115"
     CDS             94547..94963
                     /locus_tag="VYP30_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807181.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPQMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPSYQRQGIGSSLMKQALEDFKEAYQVQ
                     LATEQTEKNVGFYRSMGFETLSTYDCTGMIWVNKEK"
     gene            complement(95778..95870)
                     /locus_tag="VYP30_000116"
     CDS             complement(95778..95870)
                     /locus_tag="VYP30_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1807182.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            96031..97002
                     /gene="ruvB"
                     /locus_tag="VYP30_000117"
     CDS             96031..97002
                     /gene="ruvB"
                     /locus_tag="VYP30_000117"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1807183.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            96983..97555
                     /locus_tag="VYP30_000118"
     CDS             96983..97555
                     /locus_tag="VYP30_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1807184.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDFETDVDVIFFDPDISYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTAFYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLFKKNWQEKWKNLIFKNT"
     gene            97786..98544
                     /locus_tag="VYP30_000119"
     CDS             97786..98544
                     /locus_tag="VYP30_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1807185.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALIKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            98553..99356
                     /locus_tag="VYP30_000120"
     CDS             98553..99356
                     /locus_tag="VYP30_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1807186.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLFQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            99378..100637
                     /gene="rseP"
                     /locus_tag="VYP30_000121"
     CDS             99378..100637
                     /gene="rseP"
                     /locus_tag="VYP30_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1807187.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            100650..102503
                     /locus_tag="VYP30_000122"
     CDS             100650..102503
                     /locus_tag="VYP30_000122"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1807188.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            102603..103982
                     /gene="bglA"
                     /locus_tag="VYP30_000123"
     CDS             102603..103982
                     /gene="bglA"
                     /locus_tag="VYP30_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1807189.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            104174..105982
                     /gene="glmS"
                     /locus_tag="VYP30_000124"
     CDS             104174..105982
                     /gene="glmS"
                     /locus_tag="VYP30_000124"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1807190.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLGGAENHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERTSYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(106120..106197)
                     /locus_tag="VYP30_000125"
                     /pseudo
     CDS             complement(106120..106197)
                     /locus_tag="VYP30_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            106254..107303
                     /locus_tag="VYP30_000126"
     CDS             106254..107303
                     /locus_tag="VYP30_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1807191.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(107403..111200)
                     /gene="spuA"
                     /locus_tag="VYP30_000127"
     CDS             complement(107403..111200)
                     /gene="spuA"
                     /locus_tag="VYP30_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1807192.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            111617..112030
                     /gene="rpsL"
                     /locus_tag="VYP30_000128"
     CDS             111617..112030
                     /gene="rpsL"
                     /locus_tag="VYP30_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1807193.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            112050..112520
                     /gene="rpsG"
                     /locus_tag="VYP30_000129"
     CDS             112050..112520
                     /gene="rpsG"
                     /locus_tag="VYP30_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1807194.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            112945..115026
                     /gene="fusA"
                     /locus_tag="VYP30_000130"
     CDS             112945..115026
                     /gene="fusA"
                     /locus_tag="VYP30_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1807195.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            115130..119521
                     /locus_tag="VYP30_000131"
     CDS             115130..119521
                     /locus_tag="VYP30_000131"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1807196.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            119623..119886
                     /locus_tag="VYP30_000132"
                     /pseudo
     CDS             119623..119886
                     /locus_tag="VYP30_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            119879..120157
                     /locus_tag="VYP30_000133"
     CDS             119879..120157
                     /locus_tag="VYP30_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1807197.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPTRY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            120178..120330
                     /locus_tag="VYP30_000134"
     CDS             120178..120330
                     /locus_tag="VYP30_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807198.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            120352..121593
                     /locus_tag="VYP30_000135"
     CDS             120352..121593
                     /locus_tag="VYP30_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1807199.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(121647..>122530)
                     /locus_tag="VYP30_000136"
     CDS             complement(121647..>122530)
                     /locus_tag="VYP30_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1807200.1"
                     /translation="GISLHIRKIRYFKSPGFLEQKQKIADTIIEFNEISEYVKDIPNK
                     NQFIVKDITGKHAHLAHFENTSQHDYKRDKHKKTLNQSNVYSTSLQVVRRASEEPIHY
                     LCKYFGITATEESLKQLEEIGENISRMENTIDNLYQREKQIKTDFNPPKFILKYFSKD
                     LMKELDIHLPDIKVDYTSYIFEYVSAGGNSSQKTTILFNGETVEATAEYIAKKIKSKQ
                     TAQAQRSLMTNKLRTQIKERDHYTCQICAASTAEQSLLLLEIDHIVPVSKGGLSTPDN
                     LQTLCWKCNRSKSNKIL"
BASE COUNT        36946 a        22394 c        26908 g        36282 t
ORIGIN      
        1 aaacgttagt atagataacg taatttttga aaagaatttt gaactattta taaaacaaag
       61 tgatctaatt gttgcaaata gatgggatag gggccttgaa gcttataaag ataaagttta
      121 cacaaggggg atctggataa gagattaact attgatatta aaaaggcaat aatttataaa
      181 atttgtacaa aaaaatgtta aattttcaca ttttcatagt atactgttta atagaaagta
      241 ggttctttgt aaccgctcca ttataaaatc ctttcactct tccggtatac tattaggaaa
      301 aacataactg gaggatattt tgagctcaca cctcatcgtt ccagtggctg ttccccaagc
      361 tcgtgtactg cccaaaaaag ttagacattc tatttagaac gaggattgag ttctgtattg
      421 tacaaggctc ggtcctttta gagtcagctt aaggctggct ttttcaatca ccaaagtgtc
      481 agaatgtttt gacaaatgaa cacaaataat gatataatat gcaaaagcta ggaggtggta
      541 ggatgattga aaaaatggaa ctgggggaat tttacaagga attgcgcttg gctagaaagc
      601 tcaagcagtc agatgtggct tgtgctggac taacagcttc tcagttgtcc aagtttgaac
      661 tagggcagtc tatgctgtct gcggataagt tgattctagc tatccaaggt ataaatgtga
      721 cctttgatga gtttgggcac aagctcaaca actatcaaga atctccacat atgcgaatcg
      781 ctttgcccat caggatatag ctgctttaga gcagctattg gaggaagtcg atcaagaaca
      841 gatggcgcag acctatcgtc gtttgaatgc catcgtgatt aaagatgcca tccattcact
      901 aaataaaagc tacccactag cagaggagga tagcgagttt ttgaccacct atctctatgc
      961 tatcgagtct tggacctggt ttgaactcta tctcttttgc aataccatgc ccttcttgag
     1021 caatcaagat ctgatttttt tatcaacctc cttactcgaa aaatccaaag aatttaaaga
     1081 gttagtacac aatcgattgt atatgaagca aggactctta aatatcttat cagaactcat
     1141 ggagcgaaaa cttttctcct acatcccaat cttcgaagcc gagttggaga ggatgttacg
     1201 accgtatgat gtttttgaaa aagtatcgtg gcaattttta aagaagatga gtgtctttct
     1261 tcaaacaaag ggaagcaatc aaaaagagat tgaacgcttt atccaatctc tgcaggtatt
     1321 agaaaatcca caattaacat ccctttttga attgcgtttt cagcaataca aaaagcttat
     1381 cgattagtta gaaatggcaa aataataata atctcagcaa cgattttcaa taatgttaaa
     1441 atttgtttct tcatatttct ccactcctca ttagtagtaa ctttattata ccagagaagt
     1501 aatcaaattc accaaaatcg caaatctgaa atttctataa gaaaaaatat caaatatgcg
     1561 attttctaaa ataagctaat tttcgtgtta tactgtactt gtaaagcact tgaagcaaat
     1621 cctaggtcgc agaagtggtt tacaaatgaa gataattgaa ggagtgtaaa agatgttaaa
     1681 tttacaattt gcagaaacaa tggaattgac agaagctgag ttgcaagatg ttagaggagg
     1741 caacctcgta aattctatgg gaggtggtgg aagaagtggt atatctggtt ggggcgtccc
     1801 aggaatttac cctggttggg gcaatcaagg gatgagtcct aatcgtggag cttttgattg
     1861 gactatagat ttagcagatg gattgtttgg ccgccgtaga agataggctc ttataggaga
     1921 taataggatg aagaaaatga aagaagtgaa atttcaccta gcaactggct tgttgatttt
     1981 gacttattac ctcattttta atgtcacatc agacttagat tttatggttg ctttgtctga
     2041 taatatgtac tatgtgttcc aagttttatt ggtacttatt ctgggaacta tagctacaat
     2101 tgcttttgtc aaaagtgaac attggaaaga gtgtggtcgt ttccagtttc gttggtctta
     2161 cctgggtgtt ttccttcttt cttttttctt attgttcgtg tgggcaaatc taacaaccta
     2221 tatctttcct cgtacccaga atggaagtac agtcgtagaa gtagccacca atttaacagg
     2281 aattagctat tttgttacgc gaatacttta tactagtatt atcgcacctg tatcagaaga
     2341 ggttgtttgt cgtggtcttt tgatgacaag tttatctaaa gttaagagat actatcttga
     2401 tgttcttgtt tccgctgcca tatttggcgc tatgcatgtt ttgcagtatg gttggataac
     2461 gacagatttc ataaagtatt ttggaatggg cttgatattt tgtatgatgt ttcgctacac
     2521 ccgatccatc tattgggcta tagctctgca tgcttcatgg aatagtttct tactcattgt
     2581 tactttattg gtatttggat attagaaagg tgatatatga aaaagataat ctcacaccgc
     2641 tactttatta tagtttttct actagttatt gctgaccaga agttcagtgt tttagtttta
     2701 cgcagcgacc ttgttgctgg gctatctgac tttgcctatt atctgtcgga tatgatgttg
     2761 aattttcttg tggttttatt tgctcttatt gctatgattt ggtcggggaa atggcagaaa
     2821 atcaatagta gaaagtttaa aggatcctat cttttctatt ccttcctagc tctgcttgct
     2881 tttgttgctt ggaattttgt cacctttttt cttttcccac ctactcgaaa tgaaatttct
     2941 tatcaacatg ctgctcctac ttttacagga gctacggcat ttttgatgta ttttttttat
     3001 cctgtgattg caggtcccat ttttgaagac atgatttatc gtggattagt gatgactgct
     3061 ctggaaaaag gaaagaaatg ggggctagat gtacttggtt ccgctgtttt atttggggtc
     3121 tcgcacatta gtaatcacgg ttgggtcttg acagactttg tcttctatat gggtggaggt
     3181 cttatatttg cagtcttatt tagaatgaca aagtcaattt attggcctat tggactgcat
     3241 atagtctaca atggcattgg tcagcttttg atgttactgt aattttggtt gttagtagta
     3301 tcgcggtcta tccttgggga aagattccca tttgaactta agaaggagtt gtgatgaaag
     3361 tatttcttca aaatagagat tttaggcaat taactatcaa ccagtggatt tcaacgcttg
     3421 gggatacgat tttttatctg gcctttctga attatgtggc agatgcgtct tttgcacctt
     3481 tggcgatttt actcattacg atttcagaaa cccttcccca aattttacaa atctttctgg
     3541 gagttttggc agattttcaa catcatcgtg tcttgaaata cacagtcatt agttttgcaa
     3601 aatttttgct ttactctatc gtttctttat cactttcagg gcagtctttc tccttgttgc
     3661 tagtagcatt tatttgtctg cttaacctct tgtctgacac attgagttac ttttcaggag
     3721 ccatgctcac tccgattttc attagaatta ttgggcaaga ccatctggca gaagctattg
     3781 gctttaaaca gtcaactgtt agtttagtga aaacaatcag taatatccta ggaggagtct
     3841 tactaggcat tctatccatc cagtttattt ccttactgaa cgctcttacc tttttaatcg
     3901 catttttagg tatcctcttc ataaaaactg acctcttgaa agtagaaaaa acgattagct
     3961 atcaagaagg actctctgta aaatcctttt gccagcattt gctccaatca tcaaaattga
     4021 tatggaatat gaataaggtg ctcttggttt tgtttattat ctctactagt caagcagtga
     4081 taaatgttac ggttcctatt tccactctat ttttaaggaa ccagcccttt ttgaatttac
     4141 aaacaggtca atctcttgcc ttgctatcca cttttgaact gtcagccctg attgtcggaa
     4201 gccttgtaag tggctatctg caacatacca tttccataaa aacagctctc tatgcctcac
     4261 ttgtcatcca gttgcttctt ctagtaggat ttgccacagt tcgttttgac tggattctca
     4321 tctttagtac cttggatgcc tttttcgcag gtgttctctc tcctagattg caagaactcg
     4381 tttttaaaca aatacctgag gagtcaatgg gagcagttca atcctctatc ggtgccatta
     4441 cggttgtttt acctagctta tttacaatag ctttggtaac cattgctact agctttggaa
     4501 ctctggcagt tagctttgtt ttattgctat ttcttctagt tgcctttgtt atgcttctga
     4561 atattcgtga aagtatttag tggagaattt ctataatata tgtttgagac tggattgcca
     4621 gtctttttat gatggtcaaa atcaacagac ttttttctct tttctgaatg tgttataata
     4681 gactgaatct aaaatagtac gaaacaattg ctaaaacatt tatagaaatt aattttactt
     4741 tcccaatcga tttgttctca tcttatttca atctgctata taatagtcca tgctgtggct
     4801 ggattctttt cagcctactt gtactcttcg aaactctctt caaaccacgt cagcttcact
     4861 ttgccgtagg tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     4921 gagctgactt catcagttct atctgcaacc tcaaaacagt gttttgagca acctgcggct
     4981 agtttcctag tttgctcttt gattttcatt gagtattatt aagacaatat gaggagaaag
     5041 atgaaagaaa aaggatttta ggagggggcg caggcagcca tgccaacggc tcttggctat
     5101 gtcagtatcg gcctggcctg tggaattatc ggtgcgccct atgtgacacc tgttgagatg
     5161 ggcttgatga gtctctttgt ttatgctggg agtgcccagt ttgccatgtt ggcactgatt
     5221 gtggttcaag ctcctgtggc agctattgct atgacggttt ttctaatcaa cttgcgtctc
     5281 tttttgttga gtttacacgc atcgacttat ttccgtcata ccagtctttg gtacaatatc
     5341 ggtatgtcta gtatcttgac agatgagacc tatggcgttt tgatgggtga attggcccat
     5401 acagacaagg taaatcctat gtggatgcac ggaaacaatc ttaacagcta tgtggcttgg
     5461 tttgtgggaa cagtggtcgg aacggttcta ggtgacctgc tgccaaattc agaaatcttt
     5521 ggattggatt ttgccctggt tgggatgttc atcgggattt ttgcttcgca atttcagatt
     5581 atgcaaagac ggattcctgt ccgcaatctg ctcattatcc tagcagttgt tgcggtgtcc
     5641 ttctttttgc tcttgacagt ggtgtctcag tcactagctg ttctgtttgc gacgctactt
     5701 ggttgtagca tgggggtggt tttagatggt cagtaagtat cttttattag cagttatttt
     5761 ctctggcttg gtgacttgga ttctccgtat gattcccttc atcttagtca agtataaggg
     5821 cttgcctgca atcgttgagc gttttttgaa gttcttgccc gtttccatta tctttgcctt
     5881 gattctttca agcgtagtga caggtaaggt tgggagtctt cctcaaatta aatggctaga
     5941 cttcttagcc gtctttccaa cagcttgggt agcctttcgc taccgcaatc tagtcggaac
     6001 agttctcttt ggagtggtct tgattgccat cttgcgtttg gtcttttaaa ttacccataa
     6061 aaaaaactta tcacagagat agatatcata taatggcgta aatgctcttt ttctgttaag
     6121 attataaggt attctatttt ggaggaaatg acatgaaaaa aatcgttaaa tactcatctc
     6181 ttgctgccct aggacttgtt gctgcaggtg tgcttgcggc ttgctcaggg ggtgctaaga
     6241 aagaaggaga agcagctagc aagaaagaaa tcatcgttgc aaccaatgga tcaccaaggc
     6301 catttatcta tgaagaaaat ggcgaattga ctggttacga gattgaagtc gttcgcgcta
     6361 tctttaaaga ttctgacaaa tatgatgtca agtttgaaaa gacagaatgg tcaggtgtct
     6421 ttgctggtct tgacgctgac cgttacaata tggctgtcaa caatcttagc tacactaaag
     6481 aacgtgcgga gaaatacctc tatgccgcac caattgccca aaatcctaat gtccttgtcg
     6541 tgaagaaaga tgactctagt atcaagtctc tcgatgatat cggtggaaaa tcgacggaag
     6601 tcgttcaagc cactacatca gctaagcagt tagaagcata caatgctgaa cacacggaca
     6661 acccaactat ccttaactat actaaggcag acttccaaca aatcatggta cgtttgagcg
     6721 atggacaatt tgactacaag atttttgata aaatcggtgt tgaaacagtg atcaagaacc
     6781 aaggtttgga caacttgaaa gttatcgaac ttccaagcga ccaacaaccg tacgtttacc
     6841 cacttcttgc tcaaggtcaa gatgagttga aatcatttgt agacaaacgc atcaaagaac
     6901 tttataaaga tggaactctt gaaaaattgt ctaaacaatt cttcggagac acttatctac
     6961 cggcagaagc tgatattaaa taatttcttg aaatcatcca ttctgagtaa ggtgggtggt
     7021 ttctcagttt ttagggatat agttttaaac tatatatctg actatctaat aacaatttgt
     7081 gaaatcaaac aaattgtgag atactagtac ggtattattt ttaaggagaa agaatcatga
     7141 aaatcaaaaa atggcttggt ctagcagccc ttgctacagt cgcaggtttg gctcttgcag
     7201 cttgcggaaa ctcagaaaag aaagcagaca atgcaacaac tatcaaaatc gcaactgtta
     7261 accgtagcgg ttctgaagaa aaacgttggg acaaaatcca agaattggtt aaaaaagacg
     7321 gaattacctt ggaatttaca gagttcacag actactcaca accaaacaaa gcaactgctg
     7381 atggcgaagt agatttgaac gctttccaac actataactt cttgaaaaac tggaacaaag
     7441 aaaacggaaa agaccttgta gcgattgcag atacttacat ctctccaatc cgcctttact
     7501 caggtttgaa tggaagtgcc aacaagtaca ctaaagtaga agacatccca gcaaacggag
     7561 aaatcgctat accgaatgac gctacaaacg aaagccgtgc gctttatttg cttcaatcag
     7621 ctggcttgat taaattggat gtttctggaa ctgctcttgc aacagttgcc aacatcaaag
     7681 aaaatccaaa gaacttgaaa atcactgaat tggacgctag ccaaacagct cgttcattgt
     7741 catcagttga cgctgccgtt gtaaacaata ccttcgttac agaagcaaaa ttggactaca
     7801 agaaagcact tttcaaagaa caagctgatg aaaactcaaa acaatggtac aacatcattg
     7861 ttgcgaaaaa agattgggaa acatcaccta aggctgatgc tatcaagaaa gtaatcgcag
     7921 cttaccacac agatgacgtg aaaaaagtta tcgaagaaac atcagacggt ttggatcaac
     7981 cagtttggta ataagaaaca gggaggtggg agagagaatt ccacctcttg cttttgtata
     8041 gagcacggag tgtaaagaag actattcgtt catagaaagg tagagagaat atggtttttc
     8101 ctagcgaaca agaacagatt gaaaaatttg aaaaggatca tgtagcccag cattattttg
     8161 aggttttgcg taccttgatt tctaagaaat cagtctttgc ccagcaggtt ggactcaagg
     8221 aagtcgcaaa ttatctgggt gagattttca agcgtgttgg agctgaagtg gagattgatg
     8281 agagctatac agcgcccttt gtcatggcac atttcaagag ttcgcgtcca gatgccaaga
     8341 ccttgatttt ctataaccac tatgacactg tgccagcgga tggggatcag gtctggacag
     8401 aggatccttt tacgctttcg gtccgcaatg gcttcatgta tgggcgtggg gttgatgacg
     8461 acaagggtca tatcacagct cgcttgagtg ctttgagaaa atatatgcag caccatgatg
     8521 atttacctgt caatatcagc tttatcatgg agggagcgga ggaatcggct tcaacagacc
     8581 tagataagta tttggaaaag catgcagaca aactccgtgg ggcggatttg ttggtctggg
     8641 aacaagggac caaaaatgcc ttggaacagc tggaaatttc tggtggcaat aaggggattg
     8701 tgacctttga tgccaaggta aaaagcgctg atgtggatat ccactcgagt tatggtggcg
     8761 ttgtggaatc agctccttgg tatctcctcc aagccttaca gtctcttcgt gctgcggatg
     8821 gccgtatctt ggttgaaggc ttgtacgaag aagtacaaga gcccaatgaa cgagaaatag
     8881 ccttgctaga aacttatggt caacgaaacc cagaggaagt tagtcggatt tatggattgg
     8941 agttgcctct cttacaggag gatcggatgg cctttctaaa acgtttcttt ttcgagccag
     9001 cgcttaatat cgaaggaatc cagtctggtt atcaaggtca gggtgttaag actattttac
     9061 ctgcagaagc cagtgccaag ctagaggttc gtctggttcc gggcctagaa ccgcatgatg
     9121 ttctggaaaa aattcggaaa cagctagaca aaaatggctt tgataaggta gaattatact
     9181 ataccttggg agagatgagc tatcgaagcg atatgagcgc accagccatt ctcaatgtga
     9241 tcgagttggc caagaaattc tatccacagg gcgtttcagt cttgccgacg acagcgggga
     9301 caggacctat gcatacggtc tttgatgccc tagaggtacc aatggttgca ttcggtctag
     9361 gaaatgccaa tagccgagac cacggtggag atgaaaatgt gcgaatcgct gattattaca
     9421 cccatatcga attagtagag gagctgatta gaagctatga gtagagatat tatcaagtta
     9481 gatcagatcg atgtgacttt tcaccaaaag aagagaacca ttacagcggt taaggatgtg
     9541 accattcaca tccaagaagg ggatatctac ggaatcgttg gatattctgg agcaggaaaa
     9601 tcaacccttg tacgggtgat taacctcttg caaaaaccat ctgcagggaa aattaccatt
     9661 gacgacgatg tgatttttga tggtaaggtc accttgacgg cagagcagtt gcgtcgtaaa
     9721 cgtcaagata tcgggatgat tttccagcat tttaacctga tgagccaaaa gacagcagag
     9781 gagaatgtag cctttgccct taaacactct ggactcagca aggaagaaaa gaaggctaaa
     9841 gtagctaagt tgttggactt ggttggtttg gcagatcgtg ctgaaaacta cccttcacaa
     9901 ctatctggag ggcaaaaaca gcgtgtggca attgcgcgtg ccttggccaa tgatccaaaa
     9961 atcttgattt cagacgagtc aacttctgcc cttgacccta agacaaccaa gcagattttg
    10021 gccttgttgc aagatttgaa ccaaaaatta ggcttgactg ttgtcttgat tacgcatgaa
    10081 atgcagattg tcaaagacat tgccaaccgt gtggcggtta tgcaggatgg gcatttgatt
    10141 gaagagggta gtgtgcttga aatcttctca aaccctaaac aacctttgac tcaagacttt
    10201 atctcaacag ctacaggtat tgacgaagcc atggtcaaaa tcgagaagca agaaatcgtg
    10261 gaacacttgt ctgaaaacag tctcttggtg caactcaagt acgctggagc ttcaacagac
    10321 gagccacttt tgaatgaatt gtacaagcat taccaagtaa tggctaatat tctctatggg
    10381 aatatcgaaa ttctcgatgg tactcctgtt ggagaattgg tggtggtctt gtcaggtgaa
    10441 aaagcagcgt tggcaggtgc ccaagaagct attcgccaag caggtgtaca actaaaagta
    10501 ttgaagggag gacagtaaga tggaatcatt gattcaaacc tatttaccaa atgtctataa
    10561 aatgggttgg gctggtcagg caggctgggg aacggctatc tacttaactc tttatatgac
    10621 agttctttcc ttcattatcg gaggcttctt ggggctagtg gcaggtctct ttctcgtctt
    10681 gacagcgcca ggtggtgtct tggagaataa agtcgtattc tggattttag acaaaattac
    10741 ctcaattttt cgtgcggttc cctttatcat cctcttggca atcttgtcac cactttctca
    10801 cttgattgtt aaaacaagta tcgggccaaa tgcagccctt gtcccacttt cttttgcagt
    10861 ctttgccttc tttgcccgtc aggtgcaggt tgtcttggct gaattggatg gcggtgtcat
    10921 tgaggcggct caagcgagcg gagcgacttt ctgggacatc gtgggtgttt acctatcaga
    10981 aggtcttcca gatttgatcc gtgtgacgac tgtgaccttg atttcccttg ttggggaaac
    11041 agctatggcc ggtgcggttg gagctggtgg tatcggtaac gtagccatcg cttatggatt
    11101 taaccgctac aatcacgatg tgaccatctt ggcaaccatc gttatcattt tgattatctt
    11161 tgcaatccaa tccttaggag atttcttgac taagaaattg agccataaat aaaaaagagc
    11221 cgtgtggctc tttttaactg atcagatttt ctgggcaaat tttttactca aggcttgtcc
    11281 aatcaaggca cccactaggg ctccgatgac aatacttgcg ataaatagaa ggacagttcc
    11341 agggtttgga gcgaccatga tacggtcgat atattcttgg gattttcctc ttgccagaag
    11401 agtagccata taggctttgg gcgcaatcca cataagcaag attggtcctg ttgtactaaa
    11461 ggcgaaaata atgaaagaaa ggaagttctt tgttttgtcc ttgtattttc ctaaatgagc
    11521 tacttcatct gctaggaggc cacagataat tccaggaagg aaggaaccag caccgtgttt
    11581 agttcccaag aaaaagaagg caatgacaag gccgatagtg gtaatggctc caaagcgcgg
    11641 aacttttgcg actaggatca tatagacgct accgccgaca agggcagtaa aggcaggcgc
    11701 ataaaacatg tttccagttt ggtcaaagag attgcccaaa aggacaccaa tccccatgca
    11761 gaggaagtaa agaactgcaa aaagcagtgt agttaagata gatttcttca tgaattgtct
    11821 cctgataatt ttttcacaat tctcatttta ccatggtttg gtgggattgt aaatggatac
    11881 tagaagtttt tgaaaacgct tgaaatatga tataatggtt tcatagttat ttttagggga
    11941 atatcatggg tagattttta gactttgtct ttaatcgttt ctttttaggg atgattgcga
    12001 cagccttctt ttggctatta actttagcag gagggattat ccttggtcta gcgccggcta
    12061 gtgccacctt gatgagctta tatgcagaac atggttatag ctttcgggaa tacagtttga
    12121 aggaggcttg gtctctttac aagcaaaatt ttgtctcaag caacctgatt ttctatagct
    12181 ttttaggtgt gggtctagtt ttgacctatg gtttgtatct cttggtgcaa ttgcctcatc
    12241 agaccattgt tcatttgatt gcgacccttt tgaatgtcct agtagttgcc ctgatctttt
    12301 tggcttatac agtatcttta aaattacaag tttattttac cttgtcctat cgaaatagtc
    12361 tcaaattatc cttgattggc atctttatga gtctagcagc tgtggctaag gttctccttg
    12421 ggactgtgct acttgtagca attggttatt atatgcctgc cctgctattt tttgtaggaa
    12481 ttgggatgtg gcatttcttt atcagtgata tgttggaacc tgtctatgaa atcatccatg
    12541 aaaaattggc gacaaaatag aatgaagcag ttttggctac atacgcttct aagaacctat
    12601 agttcagtga tgatcattat cattgcgagt tttgcaatct tactctctta cgctgactgg
    12661 gattcacgtg aaaaggaagc ccagagagta gcccagcgtg taactgctag aacagtgagt
    12721 gaaattgaat attaccatag agagtcaacc cagatagctc aggctttagt tgaaaatcaa
    12781 gctcgtattg agggaatcta taaatacttt agccttagca tgccagacta tttttactgg
    12841 caattagagc ggaaagcttc gccttatata tcagtctctc tgtatgaaaa tgttgatgac
    12901 ctctatgttc gaaatgattt tgtaactgga gtggccattg cttttcaaga ttacaaggaa
    12961 gtctatgttt ctactaaaga caaacgtagt ggagaaaaaa tcagggctga ggatttcaaa
    13021 ccagcaggaa atagttttgc cattccggtg tcagatccag tgtcagatca agatttagga
    13081 gtgatttaca tctccttgga tcctgctgtt ttataccatg ccattgataa tactagaggt
    13141 catactccga tggcagtaac agtgacctca ccttttgata cggagatttt tcatattggt
    13201 gagacagttg atagggagag tgaaaattgg ctagttggct taacttctca tggatatcag
    13261 gttcaggtgg cagttcctaa aaactttgtt ttacaaggaa cagtgactag ctctgctttg
    13321 attgtgggtt tgagccttct ctttattgtc attctttatc tgactttgag gcagactttt
    13381 gctaattacc aaaagcaggt agtggattta gtagaatcca ttcaagtcat tgctcaaggc
    13441 gaagaggggc gtcggattga catttccgaa aaagatcagg aattactcct aatcgcggag
    13501 acgaccaatg atatgttgga tcgattggaa aagaatatcc atgatattta ccagttagag
    13561 cttagtcaaa aagatgccaa tatgcgagcc ttgcaggcgc aaatcaatcc tcattttatg
    13621 tataatacgc tggagttctt gcgcatgtat gcagttatgc agagtcaaga tgagttggca
    13681 gatatcattt atgaattcag tagtctcttg cgtaacaata tttccgacga aagagagacc
    13741 ctcctcaaac aggaattaga attttgccgt aaatacagct atctctgcat ggttcgctat
    13801 cccaagtcca ttgcctatgg tttcaagata gatccagagt tagagaatat gaagattccc
    13861 aagtttacct tgcaaccgct ggtagaaaac tatttcgcgc atggtgttga ccacaggagg
    13921 acagataatg tgattagcat caaggctctt aaacaggatg ggtttgtgga aattttggtg
    13981 gtcgataatg gtagaggaat gtcggctgaa aagttggcaa atatccgaga aaaattaagt
    14041 cagagatatt ttgaacacca agccagctac agtgatcaaa ggcagtctat cgggattgtc
    14101 aatgtacacg agcgttttgt gctctatttt ggagaccgct atgccattac gatagagtct
    14161 gcagagcaag ccggtgttca gtatcgtatt acaattcaag atgagtagaa agggagaaaa
    14221 tgtataaagt attattagta gatgatgagt acatggtgac agaaggtctg aagcgtttga
    14281 ttccctttga taagtgggat atggaggtcg tcgcaacagc cagtcatgcc gatgaagctc
    14341 tagaatatgt tcaggaaaat cctgtcgatg tcatcatttc cgatgtcaat atgccagaca
    14401 aaacagggct tgatatgatt cgggagatga aagagatctt accagatgct gcctatatcc
    14461 tgctctcagg ttatcaggag tttgattatg taaaaagagc aatgaacctt agtgtggtgg
    14521 actatttggt caagcctgtt gataaggtag agctgggaaa tctgctggag aagattgcag
    14581 gtcagctcgg cgagagaggg aagaaaagtc agactcttag tcaagaatta gacgaggctg
    14641 gatttgttag ttatttaggg gataaggaga attggtggat aggtctatcc aaggaaaaac
    14701 aaggttcctt caccattccc tactatgtct tgggccaaga ctggcagatt ttcatttctg
    14761 accaacccct agatggttta gtcgttacac cttttgaagc tccttatcaa gaacactttg
    14821 aacgctggaa gctgaatgct gagaaaaccc tcttttacgg ttctgtaaat ttgcagcagt
    14881 ctgagagtct ctttgcctat tacgaaccga tttatagggt tatcattcag ggaaatctca
    14941 atcaaatcgt agaagagtta aatctcttgg agaaggtagt tcttgaaaat acgccgcgtg
    15001 ttccgattac taaacagctt tttattcagt ttgtcatgga tgttttccat ttatttgaac
    15061 atctcaaagc tgatgacctg acagacatcg tcaaaaccat tcatgctatt caatccttcg
    15121 atgaattggt tccttatatc aaggaaactc tgaccagctt tttcggtcaa taccgtatga
    15181 atgaaaatgt ggtcagtgtg ctggaagtca ttggtcgtga ttaccaaaaa gagctttccc
    15241 tcaaggatat cagtaaggct ctctttatca atcctgtcta tctagggcag ttgattaagc
    15301 gtgaaaccga ttcgactttt gcagagttac taaacaaaca acgtattaag gctgcccaac
    15361 aacttttgct ttcaactagt gacagcatcg aagatatttg ttatgctgtt ggttacagta
    15421 accttggata tttctataaa gttttccgaa aattgtgcgg aaaatcgcca aaagcctacc
    15481 gaaaacaggt agaaactata ctataaaatt tgtattcctt tacaaaaggt gctataatat
    15541 tatcaggagg ttctatcatg aaaaagaaac caatttatct atgggtcttg ctaatcttgt
    15601 ctgcccttat ttcagttccg tctctgtttg gaattgtgag tcccttgcct agtaaagaag
    15661 cccttcgtgc tgctcagaaa caagttgcag gggtcaatgc tcagcaatta gaagaccagc
    15721 ttaattatac ctatagagta gcagaagcat ctcattctat ttttaatgtt gctttgattg
    15781 tgctatctac tattttagtg gtcgtagcga ttgtcttcct tgttcgtaaa aatttgcaat
    15841 atgcaaacta tacttacgtt ggctatgttt tgttagctat tattggttcg atttatggct
    15901 atgttggttt acaagacgct gtgcagttgg ttcaagatga gagcatgcgt ttgacagtga
    15961 gtattggttc aaaagctgtt agcattttct atatcgtcat caatgttctc ttcctagccc
    16021 ttgtcttcta taagatgtgg cgacaacaga aagccttggc agaagaagag gaaacagaag
    16081 agcttgccta agtattgaca aaaaagaact atcaagatac aatcttggta gttgtttttt
    16141 gattatagat aaaatcatgg aggtacatat gaagacaatt tctttagttt atattagttt
    16201 gagtggcaac actgaaagtt ttgtgacgcg cttgaaagac tatctcttgt cccagtacaa
    16261 agggattgag gttcaaaaga ttcatatcaa ggatttagtc aaggaaggca aaaatttcta
    16321 tgaaatggac catccctatg tcgctttttt gccgacctat ctcgaaggtg ggaatggcgt
    16381 ggataacgga gatgttgaga ttttgacgac accggtggga gattttattg cctatggtaa
    16441 caatgctagt aagtgttttg gtgtggttgg gtcaggaaat cgtaacttta ataaccaata
    16501 ctgcctaaca gccaagcaat acagtcaacg ctttggcttc cctgtattgg ctgactttga
    16561 aatgcgaggc atgctggaag atatcaaaca tgtcgcagct attatcgcag atttgtatga
    16621 gttggaaaag gagaattaat actcaatgaa aatcaaagag caaactagga agctagtcgc
    16681 aggttgctca aagcacagct ttgaggttgc agatagagct gacgtggttt gaagagattc
    16741 tcgaatagta taaagttctt ataagaggtg gttgaagttg ttcaactgtt ttttgagtat
    16801 aaacagtctt taagaacgta aaaaagcata agttcaggtc ttcaaaacct tgttcttatg
    16861 ctttttatca tagaaatatt tgctgaattt tctcttgaaa tgaaacctta tcttcatctc
    16921 gcgcttgtcc cttaccctgc ttttccgatt gcgagtgcgt agataaagaa gatggcgaag
    16981 ccaaagagga aaatcaatcc cgcaatggca aggtgtttga gccaagaagg aagatttttg
    17041 ttttcacgcg ttaccaaggc gtaattcaaa agagcaaaga aaggtgttgt caggaaagat
    17101 ccaatcatgg caaagcggag catggttgaa acctgaccag cgaagaactt gataatgacg
    17161 ataccgatga tagcagtgat ggtcatccag atgttcaaag atttacgatt gtcctctttt
    17221 tgactgatta gcagtcggag agattcctga ttaacgcgag aatagccatc gataacagtt
    17281 ataactgttc caaagataca gaggaaggca ataaaggtaa tcaagtaacg ggaccattcg
    17341 ccaagaacag aggcatacat gcccacgaat tgagagatgt atttggctga agcagcttca
    17401 accgcctgcc ctgtaggata ctgaatcagt gctcccagtg ccacaaagaa gacggctagg
    17461 atagctgttc caatataacc agtgttaaag tcaaacagag cgtcttctgt gttaaagttg
    17521 acggtctttc tcttttcagc tgaccaaagt gaattgatgg ctgaaatttc aataggagcc
    17581 ggcatccatc ctaggaggga gacgatgaag ggcagagctg ccatttgcca aggtgtcttc
    17641 tcgacaaaat cagaactgta ttctggatgc ttgaccgccg caatgataac tgccagaaca
    17701 gtcgcaatgg ttaaggcaga cataatccat ttgaccatgc cgtctaaaag tttgtagcct
    17761 ccaaagagta gcatagccca aatgattgca acgagaatga gggaccactg agtaatgcta
    17821 agtccaatca ttgggaaggc actggcgatg atagctgagc acagaatggc aacaccagcc
    17881 gtgttgacca tagccgaaaa gacattgagg ataaagaaaa tccagagata gagttttcct
    17941 ttttcggcat aaccttcaac caaagtcttt ccagtatcag ctgtgtattc agcaccaaaa
    18001 cggaaaaatg gatatttaaa gacattggct aagatgacca agagaagtag agaccaaccg
    18061 taagaaccgc cagcttgagt tgaggataca atgtgggaac ctccaacagc ggcagttgcc
    18121 attaggattc caggtcccat tgcttttagc ttgcttgccc aggttgattg atttaaggaa
    18181 atagcttgcg acatgataaa tactcctttt tgaattttca gaataatctg tatatgtaat
    18241 ctatattcta caaaaaattt tggaaaaatg caagagtatt ttgaaaaaag atagaaaatt
    18301 tacaaagaag atctgaaata actattatga tatagcggat tgaaactaga atagtacacc
    18361 tttgcttcta aaacattgtt agaaatctat ttgactgtcc tgatcgattt atcctgttct
    18421 tatttcattt cactatagta aggtgcagca ggataaagaa aaaccgagaa gtttctttct
    18481 cggatttgct tattatgagg ttcctatttt ctatgctcca agagttgatt gatgtgatct
    18541 acttttttag cctctctttt atagagaata gcccagatga tgagatagac aatcgcaaac
    18601 tcgataatga gctggaggta gaaaatccag tggaaaggga accaaccagc aagagttgct
    18661 agtgggacaa agccagccag cataaggaag aaatgagtca gagtggcacg aagcatgctc
    18721 cagtcacggc taaataagcg gttgccaaag ttgaagagca taccgatggt tgcccagata
    18781 agtgtgcagt agagcaagac cagggcaccg tgaacctgat gctgatccat cacttggccg
    18841 atgagagagt agggatttag tggtgcgtag gtatttggtg cataaatgag tgaaaagagg
    18901 atagagagga tgaggccgat aagaacaccg gtagctgcat cgtgaaatac ttgttttttc
    18961 atagttctaa tttctccttg atggttttta gataacggcg tgaagagtag gtgaagcttt
    19021 cgtttttcaa gaaaatttct accagaccgt ttggcgtgag cttgaggtga gagatggaat
    19081 cgatattgat gatttctgat tgggaaattt ggacaaaatt ggttggcaag agtttaagaa
    19141 cctgatagag tcgcaaatca atgctgtagg tctgactcgc ggtttctgct agaaccttcc
    19201 gattctcgat atagaagcgc tgaatcttgc caatctcaac tagatagacc tgatcatcga
    19261 tttttccttt gattttttct ctttggtcca gattttctgc gaactcgatg actttctgga
    19321 ctttttcggt ttcttgaggt gcttggacaa tcagcttttc ctcctcgtaa gtctcactaa
    19381 tctgtagttc tactttcata gttttctctc cttttcagtt atacaaggtt gtgatcactt
    19441 cctgtatatc cttattaaac actattttat agcccatggc aaggaacctt gtctatgtgg
    19501 agggattggg ctcctatgtg gtggagcttt tctgttcttt ctgaaatatg gtataatagc
    19561 actaatcaat ttctaggaaa atagatacag aaaggggctg aaagatgtct catattattg
    19621 aattgccaga gatgctggca aaccaaatcg cggctggaga ggtcattgaa cgtcctgcca
    19681 gtgtggtcaa agagttggta gaaaatgcca ttgacgcggg ctctagtcag attatcattg
    19741 agattgagga agctggtctc aagaaggttc aaatcacgga taacggtcat ggaattgccc
    19801 acgatgaggt ggagttggcc ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag
    19861 atctctttcg gattcggacg cttggttttc gtggtgaagc cttgccttct attgcgtctg
    19921 ttagtgtctt gactctgtta acggcggtgg atggtgctag tcatggaacc aagttagtcg
    19981 cgcgtggggg tgaagttgag gaagtcatcc cagcgactag tcctgtggga accaaggttt
    20041 gtgtggagga tctctttttc aacacgcctg cccgtctcaa gtatatgaag agccagcaag
    20101 cggagttgtc tcatatcatt gatattgtca accgtctggg cttggcccat cctgagattt
    20161 cttttagctt gattagtgat ggcaaggaaa tgacgcggac agcagggact ggtcaattgc
    20221 gccaagcaat cgcagggatt tacggtttgg tcagtgccaa gaagatgatt gaaattgaga
    20281 actctgacct agatttcgaa atttcaggtt ttgtgtcctt gcctgagttg actcgggcta
    20341 accgcaatta tatcagcctc ttcatcaatg gccgttatat taagaacttc ctgctcaatc
    20401 gtgctatttt ggatggtttt ggaagcaagc ttatggttgg acgttttcca ctggctgtca
    20461 ttcacatcca tatcgaccct tatctagcgg atgtcaatgt gcatccaact aagcaagagg
    20521 tgcggatttc caaggaaaaa gaactgatga ctctggtttc agaagctatt gcaaatagtc
    20581 tcaaggaaca aaccttgatt ccagatgcct tggaaaatct tgccaaatcg accgtgcgca
    20641 atcgtgagaa ggtggagcaa actattctcc cactcaaaga aaatacgctc tactatgaga
    20701 aaactgagcc gtcaagacct agtcaaactg aagtagctga ttatcaggta gaattgactg
    20761 atgaagggca ggatttgacc ctgtttgcca aggaaacctt ggaccgattg accaagccag
    20821 caaaactgca ttttgcagag agaaagcctg ctaactacga ccagctagac catccagagt
    20881 tagatcttgc tagcatcgat aaggcttatg acaaactgga gcgagaagaa gcatccagct
    20941 tcccagagtt ggagtttttc ggacaaatgc acgggactta tctctttgcc caagggcgag
    21001 atggacttta catcatagat cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc
    21061 gtgaaagcat tggcaatgtt gaccagagcc agcagcaact cctagtgccc tatatctttg
    21121 aatttcctgc ggatgatgcc ctgcgtctca aggaaagaat gcctctctta gaggaagtgg
    21181 gcgtctttct agcagagtac ggagaaaatc aatttattct acgtgaacat cctatttgga
    21241 tggcagaaga agagattgaa tcaggcatct atgagatgtg cgacatgctc cttttgacca
    21301 aggaagtttc tatcaagaaa taccgagcag agctggctat catgatgtct tgcaagcgat
    21361 ctatcaaggc caatcatcgt attgatgatc attcagctag acaactcctc tatcagcttt
    21421 ctcaatgtga caatccctat aactgtcctc acggacgtcc tgttttggtg cattttacca
    21481 agtcggatat ggaaaagatg ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt
    21541 tggggaaata ttaaaagtat aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca
    21601 taaaatcagg tgttcaaaaa ccttgatttt atgcgtttta tcatagaaat atttacttca
    21661 ttttttccta attcttttcg aaactctttt taaacgacgt cagttttatc agtaatctca
    21721 aaacagtgtt ttgagctaat tttgccagtt ttgtctgtaa catcgaagtt gtgtttgacc
    21781 actctgcgac tggtttccta gtttgctcta tgattttcac agagtattaa attgcgattt
    21841 tgccaagttt ctttattcgt ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt
    21901 aggttgacca tttcaatagc tccttgtgca cactcagaac ccttatttcc tgctttagta
    21961 ccagctcgtt ctatggcttg ttcaattgta tctgtcgtta gcacaccaaa cataacagga
    22021 atttcgctat ttaaactgat ttgggcgatt cccttagata cctcgctaca tacataatca
    22081 taatgacttg tattccctct aatgacagct cccaagcaga taattgcatc atatttttta
    22141 ctttttgcca tttttgatgc aatcagtgat atttcaaaag ctcctggaac ccaggctacc
    22201 tctatatctt tctcgtttac attctctctt ttgagattat ctagtgctcc agataataat
    22261 tttgaagtta taaattcatt aaatctcgct acaacaatac ctattttaat attgtttgct
    22321 actaaattac cttcataagt gttcatttat ttttcctcca tatttaaaat gtgacccatt
    22381 cgatttttct ttgtttctaa ataaaaacta tcgtaaggat tggcttctat ttcgattgat
    22441 attctactgg aaatagtaat tccatatttt tctaactgtt caaccttgtc aggattattt
    22501 gtcagtaaat gaagtgactg aagtcccaga tctttaagca tttgtgctcc aatatgatat
    22561 tctcttaaat caccttcaaa gcctaatgca agattggcat caagcgtatc catgccttga
    22621 tcttgtaaat gataggcttt taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc
    22681 aagtaaagta agacacccga accattctca acaatcattt tcatagcttt atcgaattgc
    22741 tgtccacaat cgcaacgtaa agagcctaaa acatcccctg ttaaacattc ggagtggatc
    22801 cgacataata cattggcttc atcctctatg tttcccataa taagagcaag atgatgttcc
    22861 ccatttagtt tatctatata gctaattgct ttgaaattac cgtatctagt aggcatattg
    22921 acagttgaaa ctcgttctac cagctgatca tatacttttc tatattcttg taattctttg
    22981 atggtaatta gtggaatgtt gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc
    23041 attttgccat catgattcat tatttcacaa cataggccac actcttttag tccagctaat
    23101 tttaataaat caacagttgc ttctgtgtgt ccatttcttt ctagaacacc accttttttt
    23161 gcaattaaag gaaacatgtg tcctggcctg cgaaaatcag agggtgttat atcttcagct
    23221 acacacatac gtgcggtcag tcctctttcc tcggcagaaa tacctgtggt cgtttcttta
    23281 taatcaattg aaactgtaaa agcagtctta tgattatctg tattgttttc aaccataggt
    23341 gaaagcatta attgattagc taaactttcg ctcataggca tacaaattaa tcctttggca
    23401 taagtagcca taaaattaac attttctgtt gtagctgctt gtgcagaaca aattaagtct
    23461 ccttcatttt ctctatcctt gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct
    23521 tctaatgttt cttgtatttt tcgatattcc attgactgat tatcctttct gctaaaatcc
    23581 attttgatat aatagttcct tagatatttc tgattttgga gagttatcca tcagtttttg
    23641 cacatattta cctaagatat cattttcaag atttactgta ctcccgactt gtttactttt
    23701 aagaatggtt tgtttcaagg tatgagggat aacagatact gaaaagttta ctttggagac
    23761 tttagcgaca gtcagactaa tgccgtcaat tgtaatagat cctttttcaa ctattaaatc
    23821 taaaatttct ttttgtgtgt tgatttgata ccatacagca ttatcatctt tttttattga
    23881 cgagattttt cctgtaccat caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt
    23941 gatagataag gctctttcta gattcacctc acttccatgt tttaatagag taagagctgt
    24001 tcgactccat gtttcattca ttacatcaac tgtaaaggat tgatgattga aatgagtaac
    24061 tgtaagacag ataccattta ctgctatact atcgcctaaa tggatatccg ttaatatttt
    24121 tgaggcttta attgatagtt tacaattacg agagtctttc tgtattcttt caacttttcc
    24181 gatttcttca attattcctg tgaacatgga taaatcactt cactttctat gagatagtca
    24241 tttcctattt gagaaaaagc ataaggtttc aatctaatag cgtcatttgg caaagaaatg
    24301 ccttcacctc cgacaggaaa cttggcactg cctccaaaaa tttttggtgc aatatatatt
    24361 ttcagctcat caacaatttg ttgttccaaa gcactccaat tcattagact gcccccttct
    24421 agaactaggc tatcaatctg catgtttcct agatgttgca ttaaactcga taagtctata
    24481 tgattgcctt ttttctttat ggaaagtatt tcacagccat gattttgata tagcttcatt
    24541 ttatttttgt cttcagagga agtggcaatg taagttttaa tatcatttgc tgtttttacg
    24601 attttagagg taagaggagt tcgtaaatgt gtatcgcata tgatacggat aggatttttc
    24661 ccttcctcca atctacatgt cagcaaagga tcgtcttgaa taacagtatt gactcccacc
    24721 ataattgcac taacatggtg tcgtaactga tgcacatgct ttcttgcttc ttcttcagta
    24781 atccatttgg attgatttgt tttagtggct atttttccat ccattgacat tgcatatttc
    24841 ataaaaacat agggtacatg ctgggtaata tactttctaa aactttttat taagttaaga
    24901 cactcatttt ctaaaattcc aacagtaact tgaagattat tttcctcaag tatctttact
    24961 ccttttccag atacaatagg attacagtct aggcttccaa tgactactct tgtaatacca
    25021 ctatcgatta tagcatctat acagggaggt gttttcccga agtgacaaca gggttcaagt
    25081 gttacataaa gcgtcgctcc gacaggggat tctctacagt ttttaagagc atttctctca
    25141 gcatgtgggc caccaaaaaa ctcatgataa ccttgtccga tgatgtgatt atcttttaca
    25201 ataactgcgc cgaccatagg attgggattg acgtaaccag cccctttttg tgccagtttt
    25261 attgctaatt tcatatattt tgaatcgctc atctcactac ctccaaaaaa aatatacctt
    25321 gaatagggga ctactcaagg catacaaaag aaaacttatg cgattaacaa aaatactctg
    25381 aaatgacaag taatcatttc agagcacgca aaaagcacaa atatactttt atcttctttc
    25441 atccagacta tactgtcggc tttggaattt caccaaatca tgcctttcgg ctcgtgggct
    25501 ataccaccgg tagggaatta caccctgccc tgaagatagt tattcaatta cagatgatta
    25561 tagtacttaa ttttgaatat gtcaacagat aaataccgat tgtttttgat atactgtatt
    25621 tgtgataatc gattctcgct cctcggataa agaaaatatg atatactaga taaacgaaat
    25681 aagagagaag gaatactatg tacgcatatt taaaaggaat cattaccaaa attactgcca
    25741 aatacattgt tcttgaaacc aatggtattg gttatatcct gcatgtggcc aatccttatg
    25801 cctattcagg tcaggttaat caggaggatc agatttatgt gcatcaggtt gtgcgtgagg
    25861 acgcccattt gctttatgga tttcgctcag aggatgagaa aaagctcttt cttagtctga
    25921 tttcggtctc tgggattggt cctgtatcag ctcttgctat tatcgctgct gatgacaatg
    25981 ctggcttggt tcaagccatt gaaaccaaga acatcaccta cttgaccaag ttccctaaaa
    26041 ttggcaagaa aacagcccag cagatggtgc tggacttgga aggcaaggta gtagttgcag
    26101 gagatgacct tcctgccaag gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag
    26161 aagctatgga agccatgttg gctctgggct acaaggcaac agagctcaag aaaatcaaga
    26221 aattctttga aggaacgaca gatacagctg agaactatat caagtcggcc cttaaaatgt
    26281 tggtcaaata ggagcagaga atgacaaaac gttgttcgtg ggtcaagatg accaacccgc
    26341 tctacatcgc ctatcatgat gaggagtggg gtcagcccct ccatgatgac caagcattgt
    26401 ttgagttgtt gtgtatggaa acctatcagg caggcctgtc ttgggaaacg gtactcaaca
    26461 aacgccaagc tttccgagaa gcctttcata gctatcaaat tcactcagtc gcagagatga
    26521 ctgagactga attggaagcc atgctggaga atccagctat cattcgaaat agagccaagc
    26581 tttttgctac acgcgctaac gcccaagcct ttctacagtt acaggcagag tacggctctt
    26641 ttgatgccta tctttggtct tttgttgagg ggaaaactgt cgttaacgat gttcctgatt
    26701 atcgccaagc cccagctaaa acacccttat ctgagaaatt agccaaagat ctcaaaaaac
    26761 gaggcttcaa gttcacaggc ccagtcgccg tattgtcttt tctacaggct gcagggctag
    26821 ttgatgacca cgagaatgat tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa
    26881 ggaaattctg atttttgcga ttctctatac agtcctcttt gtgtttgatg gcgttaaatt
    26941 gctggcttct ttaatgccat ctgccattgc aaattatctt gtttatgtag ttttagctct
    27001 atatggctcc ttcttgttca aggatagatt gatccaacaa tggaaggaga ttagaaagac
    27061 taaaagaaaa ttcttctttg gcgtcttaac aggatggctc tttctcattc tgatgactgt
    27121 tgtctttgaa tttgtatcag agatgttgaa gcagtttgtg ggactagatg gacaaggtct
    27181 aaatcagtct aatattcaaa gtacctttca agaacaacca ctactgatag ctgtttttgc
    27241 ttgtgtcatt ggacctctgg tagaagaatt atttttccgt caggtcttat tgcattactt
    27301 gcaggaacgg ttgccaggtt tactaagcat tattctggta ggacttgttt ttgctttgac
    27361 tcatatgcac agtttggctc tatcagagtg gattggtgca gttggttact taggtggagg
    27421 ccttgccttt tctattattt atgtgaaaga aaaagagaat atctactatc ccctacttgt
    27481 tcacatgtta agcaacagcc tctccttaat cattttagct atcagtatag taaaatgaaa
    27541 tgagaacagg acaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
    27601 ttcaatatac tgtaatatgt gatgaaaatg ccagtaatga taccgagaaa aaagctgaga
    27661 aacttttccc agctttattt gttatagtca aagagaatga cttgttcctg tgcatctaca
    27721 tgagcatgga ccccaaaggg tacaattgct cttggagttg cgtggccgac attcagatta
    27781 tagacaatcg ggatattgct gtcaatgata tccaatagtg cctctttata gtcgtcatgg
    27841 aaagtttcat ccataggttt tccgaccaag agtccattga tgaccgcgaa tatgccagtg
    27901 tcctttaaag ttagcaacat ctttttgaag tcttctgact taggcttttc ttcgcttgtt
    27961 tcgagcaaga ggattttccc ttcccagtct gacaagtcag ggaaaagttt gtatttttgg
    28021 cagagttccg tgctatctgc gtatcgagag ttgtcaaaga tatcgtagag ggattcgagg
    28081 caaccaccga ggattttccc ctcgaactgg gcccttcctt gcaacaagtc aaaacctgta
    28141 tttgtatgac tgacacgagg tgttcccagg gccgtgggac taaaatcagt tcgttcctca
    28201 taccaaacgt cactagggcg gatttctgaa attcttcccg tctcaatcaa ttctttaaag
    28261 tagtgaaggc tataggctag catttctttg tctaattcac aaatgtctgc taaaaaggat
    28321 tgaccataaa aagtcttgat tcctaattta tgcaacatga ggtggttcat ggttgtatcc
    28381 gagaagccaa gaaaaatttt ttgtttgata accttttgga gttggtcatt ttcaaaaaga
    28441 taaggtagca agcgataggt atcgtctcca ccgatggcac ataggatcat gtcgatgcta
    28501 tcatcagaaa aggcatgaat caaatcctct gcacgagctt caggatggtc cttgataaag
    28561 tctaatcctt ttaacgaatg gggcaaaaag atgggattga gtcccagatc cttgagacgt
    28621 tggataccca agtccacttc gtgtttgaca aaatcctctc cgataatgcc actagataaa
    28681 ctaacaatac caatagtaga aaccatatct catcctccta gaaatagatt gagcctattt
    28741 tatcacaaaa tataagagaa agctatgtgg gatttcagaa gaatactttt aatactcttc
    28801 gaaaatctct tcaaaccacg tcagttttat ctgcaacctc aaagctgtgc tttgagcaac
    28861 ctgcagctag cttcctagtt tgctctttga ttttcattga atataactca aaaaagtaag
    28921 tgaaaaagca accgcacctg cagttgcttt tatcgttttc ttattcttga tagcgtgttg
    28981 gtcctgcact tgcactacgg atattcaagc gtttcttgag atagaagcga agggctagga
    29041 gggctgctcc aataatagct agtggcaatg gatccagtac tgggttaagg ctagctggta
    29101 ggaagcttgt tgcaaagaag acaagcaacc aaaggaacat agaagctagg ataactagta
    29161 cagatttcca gaaaggtgga cgttgactgc gatccatatc tggtccatag tattggtaaa
    29221 caaagtagta catcaagtag aaggcaaatc caccaaccag tccaactaat agaagagtaa
    29281 tcaatccata gccgaaagct tggtctgccg caaagaaggt tgtgagggcg ctgacaaggg
    29341 caaagaggct agtgatgaaa agagctgagt ccataatcat cagttttggg tcatcatttt
    29401 cttttggatg ctctttttcg tactgctctt tgacagtgaa gctatgagcc caatgagttg
    29461 gtgcgccgta tagggaacgg gcagttgtac ctttagattg ctcctcaagg atttggggaa
    29521 tgacttcctc aaaaatagtc tggatttcag cgtctgtttt cccatctttg atgaattgtt
    29581 gggtagcaat gtggacaaac tcttggtttt tcttagttaa tttttgtaga tcaatttgag
    29641 acataggaac tcctcttaga accatttttt atggatgaga tagagagtga gcgagacact
    29701 catagcaaag gcgataaaga cgattaacca gaaggcattt ggctctccgt ttagggggat
    29761 ttcattatcc ttaaagttca tcccgtaggc agaaaagacc atggttggga tggacatgac
    29821 gatggtcaca agggccaagg ttttcatgat gttgttctgg ttgttagaaa tgatagaggc
    29881 aaaggtctct gtcatagaat gcaagacgtt tccataaata tctgccatct cgatggcctg
    29941 ttgggtttca atcagggtgt cttcaagcag gtcttcgtcc tcaaggtatt tcttgatatt
    30001 gctggttgaa ctggtcaatt tcttaatcac gcgctcattt gttttgaggg aggccttgaa
    30061 atagacgata gttttttcca attccatgag ctcaatcaat tcttcattac gagttgattg
    30121 atgcagttga ctttcgattt gttcactctt gcggtcgatt gaacgaaggg ctgttaggta
    30181 aagctctgca ttgcgataaa gaatttgaaa gataaaacgt gaacgcatga aggtatagaa
    30241 attacgcaat cgacggttga taaagacatc aaggacaggt agtggttcca aacacgtagt
    30301 gataatggtt tcctcagtga tgataatacc aagcgggatg gttacgtagt aggtgcggtt
    30361 atttctttcc tccgtgaccg gcacgtctac gataatcagg gtatactcgt cttcaatggt
    30421 aatacgagac atttcttccg catcgagcgg tgctcgaagg tcggcaatat caatatcgaa
    30481 ggtgttggcg atttcgagtg attcattttg agtcggattg acgagattga tccaagtacc
    30541 cggttcaagc gtatcgatct ctttaaattc agttgttgta gagagaaaaa cttgtttcat
    30601 atcccttatc ccttatcctt tctcattttt cagatttttt cacactgtac tattatacta
    30661 caaaatcggc ctttttcaaa ataaatctaa caaaaaacct gttgctattg gatttttgct
    30721 ttgtcttgaa atgttgattt ttaaatttgc tccccctata gtgcttttag tgcagtttcg
    30781 tagaatgata ctgctttttt tgcgttctct tttgagaggt ggctgtatat atccatggtc
    30841 attgataaag tggaatgacc taggcggtac tggagttctt tgtatggtat tccagagtta
    30901 agcaagagac tagcgtgagt gtgacggaat ccgtgaaagc caatgttagg aacgtcagca
    30961 cgcttaaaat gtgtttgcaa tcttctttta agtcttgaac tgctaggata ctcatgaatg
    31021 aagtcagaaa atactacact ttcacgttgc cctatcttcc aagcctcttt agtttggcgt
    31081 agtttgtact gcttcagcat gctaacagtc gcttgatcta tatctatatc ccgataacta
    31141 gccttagatt ttgggctatt aatttctaaa tcacgattta gtgttttggt aacatgtacc
    31201 acggcattat ctaaatctat atcagaccag gaaagagcta aagcttcatt gatacggcaa
    31261 ccagtagcca ataggaactt atagagcgtt gtctcatagt agtaacgata tctatcgcta
    31321 tctaaattat cgagataacc aagaaacttt tttagttctt gattttcaaa gtgttttact
    31381 tttttccgct ttgctttctg agtgttacga ggtaaaacaa catcacgggc aggattggac
    31441 ggtatagcct gcatagttac gccatactgt aagatacgtt tgtttagagc gtgtatcttg
    31501 tcataatgta gaaaagcccc tttttcccct ctattagtct tgtcagcaag ttcgttgata
    31561 attgactgga taagtggagt agtgagttta tcgagcttat aagccccaaa aataggcaat
    31621 atatgattat caattaactt tctaacattg tcttgagtgt ttggcttaac cgtattctta
    31681 taactttcta accagagatt ggctaattct tgatagtttt ttatggtgct agccttttgt
    31741 ctagtagatc ctgctttttg aaaagctatt ttttcttgag tagctttctg cttaacttcc
    31801 ttttgtgtcc gtcccgttac cttagtttta actttctttc ctgtaacctg gtcaactcct
    31861 agatatatat tagcacgata gactttacta ccgtcttttt ttataacctc agttattttc
    31921 atgatttaaa cctttctaaa atacatcagc aggcaagcca ttatcaaaaa ggttttatat
    31981 catgctaggt cttcacagat tgccctgtat tcgattttaa ttagtcaggc ggtaaataat
    32041 accaaagttt gaaacaaggc ggatatgggg cttatatggg cttgaagctc gaacgaagct
    32101 tgagaaatca cgcgcagaac gtgaaaaaac atgaattttt tgaagatttc aaaagctaga
    32161 aaaaccagta cttacaagtc tttcaatggt tttaagttat ttgggttcat gttgacaaaa
    32221 gttgacattt tcagagtata acataccaaa aaactaggaa aacttatatt tcagtttttc
    32281 aagatagtaa caaatgaaaa tttttaaaaa ggtaactcaa atttgcaatc aacaattttt
    32341 gaactaacaa taatttgaat atcttcgctt aaaagctggt caacatgtcc tgaagaattt
    32401 tttgcaaaaa caaactcttc tttgaattct tgtattaaat actcttttat atttttacca
    32461 actacttgaa gtaaatcgtt tgtaaaaata ttttggaaat tgctaggtaa tttagtgaat
    32521 ttatcataag tttctttgtt ttgtttcttc aaacaaactt tcactgtgat aatttctact
    32581 tgctgatagt tacgcttaat ttcctcaata ccaacaagat tatctggctt attagtgttt
    32641 atatgaaatt caaggtccac tttatactct agtgtagcaa ccggtctatc tctatctaag
    32701 attttaataa aagtaaatat atctccacta tcttcgtcga taaaatattt tatctcataa
    32761 tctattggag aataatcaaa aaaatcgtcc gaagtaaccc ctaaagtgtt acagatttta
    32821 ttaacagttt cataatcaac ttgttttgat ttatttgaag taatcttaga aattgttgat
    32881 tgtgcaattc ccgtatcact tgctaaacgc gcaccactca ttgacctttc agccaatagt
    32941 atagccaatc tatttattaa cataatacca cctcttttta tttattatag cgcacacgct
    33001 aataaaagta aaatataaaa taataattta agtgttgaca atatgtttta tatgttgtac
    33061 catatcatta aattagtcat tgcgctataa tgattagtta ataaaaaata ataaggagcg
    33121 cctatgctaa aaaataactt actaattgtt tttgctgaaa aaaagactaa tgctagtaaa
    33181 gtttccaacg aaacaggtat agctgagtct acaatttcaa acttaacaaa caacaaaact
    33241 gacgtaaagc tttctaccct tatcaagctt tgtaacgctt taaaagttcg tttgtctgat
    33301 ttaattgaat tttcaccaga aaattagaaa ggagcaaacc aatggaacta gtctacatgg
    33361 acggaaagaa agagccgtat actacgagtg agatcatcgc tgaatgtgct ggagtcactc
    33421 atcacacaat acaagaactt ttaaggaagc ataaagctga ttttgaaagc tacggaatta
    33481 tcgcatttga aatgcgtaaa ttagacggcc gagggagacc aatgaagata tatcgcctaa
    33541 atgaacaaca agcgaccttg ctgatcactt atttaaagaa tactgaacct gtacggcggt
    33601 tcaaaatgaa cctagtcaaa gcattctttg aaatgcgtga ggagctttct aagttccgta
    33661 tgcagagggc gctagaaaag ccaaaaagaa aaaccttgca tgacagtata gagacatggg
    33721 aggcaaaacc caagcacgcg catagcacca tgaacaacct gctactaaaa gcagtaactg
    33781 acaggaacgc taaacagtta agggaagaac gtgggggcta caatggtatt gatagcttga
    33841 ccagtgacga gctggagcaa taccaggcat ttgaggatat ggtaatagcc atgatcggct
    33901 tgaatatgag ttaccaagaa atcaaggcta tggcattcag aaataaaaaa acacgccaaa
    33961 gaagcgcgtg attgcaacaa aaaaggctta ccgagaccaa tcagcaaagc ctttcacact
    34021 atgactaaaa cgaatttaac aaaaagcagg caagctatta tcaaagaggt tttagtaaag
    34081 atttatacct agattatagc atatttaggg caatttgacc atacggagag cgccaactct
    34141 ttaaactggt actttctcac gctttcaatt tggcgagtct gagcgtgagg aatagcgtta
    34201 taagaaacaa ctcaaaaagc cccacgttca gaaatttggc gaccgagagc atgaggctgt
    34261 agacaagaaa aactgtataa gaaacaacca ttcaaaatcc ccacactcgc catcgctcaa
    34321 ctttgagtgt gaggatatcc tggatagtaa aaggcattaa aaagccctta gggcaactac
    34381 acaacataga aacagaggta aaaatatgga agaaacagca tacgagaatt taactagacg
    34441 tatagacaga attagcgcag aaatgcgaga aattggcgaa aaaactgggc ttagtagact
    34501 ttcgttattg gcaaatcaga caaaattcat caaagaaaat ttacaccgtt tactttggat
    34561 tgaacttcct gaattgaatg acagctataa aatcgaggca gtttctaaaa gcactacggg
    34621 aatgtttttc caccctggta tttttgaaat ggacgctatg cgacaagcat tctttaaacg
    34681 ccaagctatg cacttttttg agaacgaagc agagcaacag gcgtatatag aacatgctga
    34741 aaaggagtat ttagaggcta ctataacctt aaaagatatt ctttttaact ctaaaaatgg
    34801 aactcagaga gtaaataaaa gttgtcttat agagaagttt gaggaggcaa tgcaatgaca
    34861 ctagacctag acaacatgac acaagcagaa tttgataaac aaatggctga aatcaaggag
    34921 agaaatccga atctcttcca gtttattgct gattttgtag atagaaaggt aacacccaaa
    34981 gaggtagatg agtttttgaa gatgggacga agcgaccaag tggactacat caagaactat
    35041 aaagcgaggg catgacatga atgaattaga tttgaccaat acacaggcgg taatctctat
    35101 ggtggtactg attggcttac tgctttattt aaaccaccga gaccgtaaaa aaagcgccca
    35161 atttgagcga gaaaaccaac agacgataga aacacctagc gaggatttaa gccctgatta
    35221 tgggcgttat atccagcttg caggggtaag agtttacgga gggatgaaat gagttacaca
    35281 atgaatttat accccgatat tgaaaaaata tcagacgaaa cctattttac cagagagatt
    35341 tttctagcaa cgtgcttgaa taacacaatc agaatagcag tagccagagg agtgctaaca
    35401 tctcaacttt tagacaaaga aactaaagaa gttgtttgta aaaccttgga tacaatcata
    35461 gaaaatcaaa aagctatttt gcaaggggta gcaagcggac aaataacctt tttgaataaa
    35521 agcaaagaag aggaggaact gaatgagtct atcagagaat gacaaacgag tattaagact
    35581 aatcaaggta ggtgctgaga actccataac aggggcagaa atcagcctga tcactaagtt
    35641 agcagaaaga accgtgcaag atattatcag ccgtctgatc atgcgctacg gcattcctat
    35701 catcggggta cgtcatggaa catttagagg atattttatc ccagctaaca aagaggagtt
    35761 actggacggt gcaaaaacat tttacaatca gatacgagaa gaagaaaagc gcctaactgt
    35821 ccttttaaat gctgatttag agagttataa gcaactactg aagggggcgg acgaatatgt
    35881 ttagcctaag ccaagaaagc gagcaagacc tagcgcatgg cattctggag gtagtggaaa
    35941 gatacctgga agcgcgtgat acagtcaaac cacgactgac aggtttaata tcagcccagg
    36001 aagtcatggg cgagttagat ataaaataca tgacactcca aaaatgggaa aaagcagggc
    36061 taagacggta tcagccaccg ctagaagata ctaggaaaat ctattataaa atatctgaca
    36121 tctggaagtt tttgggggtg gaaaatggca aggtatagta ttcatccggc agataataaa
    36181 gggcattatc acaatattaa attttacaaa gagcgcaggc caaccctaga ccagctaaag
    36241 gaacagcaaa ggcttaaaaa gctgaagaaa aaacgtagaa aggggcgata atgtggcaat
    36301 ttatgaggct aaaggctttc agagtaatct tgtctatcca tttgataaaa ttgagccgtt
    36361 ccagtacatt gaactcttta agcctttggt agtccctgaa ggggcaaaca ttgaagaatt
    36421 taaacgtaca caagcgccct actgtatcag tgggaaagtg acaccagaaa agaatggcag
    36481 ttacaagcga aacaactcca gtctaatcta tcgggatttg attttccttg attatgacga
    36541 tatacagggg acgactgagg acttcataga agccgtttct agcactttgt ttggctactc
    36601 ttatatctta tacccgacta tcaaacatag catagaaaag ccccgttttc gccttgtggt
    36661 gaaatctaac aacgtgatga acgaggcaac ctataagcag gtagtaaaag agattgctga
    36721 caagattggg ctaccctttg acatggccag tttaacctgg tcacaactcc aagggctacc
    36781 agtaacaaca ggcgacccag caacttatca aaagattgta gagcatggac ttgattatcc
    36841 agtccccaag gttgaaccaa gagcgaagca aggaactact gagcgttata aacctagagt
    36901 aagtggccag aggtcaatga ctatgaggat tattgacacg cttttcaacg gatttggaga
    36961 cgaaggaggg cgcaacgtag cgctgacacg ctttgtggga ttactcttca ataagtgggt
    37021 tgattgtgac ctagagaccg cctatgaact gacaaagata gcaaatagcg tgacagttga
    37081 accattgcct attgaagagc tagaccgcac ttttagcagt atagcacggg ctgagtatag
    37141 aaagagaggt tagaaccata gaactagaag aattagcaaa cctaaaaagt gaaatcatgg
    37201 aggtcagaga gcaagaacac cctcctagaa cgatgaagga gcttgaaaat cgtatcttta
    37261 aagctggtga agaatggcgg gcagaacata ccgaaactaa ggtaaatgag accacagggg
    37321 acgttactga aaaggttgcc atacctcaga cattcactgt agctaaaata ctgagcgaga
    37381 ttgtcacgtt tacttttatc agcaagagca atatagctga ttatagtcta ctctatatct
    37441 acgatttaga cgagggtatc tatacagcta gtaatgatct atttaatcta ttgtgtaaga
    37501 cttttgatgt gagaattaaa cccagagagt ggccgcagat taagttaatg gttagaacac
    37561 taacaaagat acgaaaacct ttagaaagtt ccaacctcat tcccgtacag aacggaatta
    37621 tcaacttaga aactaaggag ctattcccct ttagtcctaa gtatgtaatt acaagcaaga
    37681 taagcacggc ataccacgcg cctaaacgag tcccaacaga tagagaggga aaaacttttg
    37741 atgattggct aaactcaatc gcttgtaatg atagtgagct agtgacactg ttttggcaaa
    37801 ttatccttga agctatcaac tctaaccata cccgaaataa gtttgctatc ttctacgggg
    37861 acggtaacaa tggtaaaggg acatttcagc gctttcttat caatctgata ggggaaagca
    37921 atatatcagc cttaaaacct gcacagtttg ctgaaaagca taacttagaa accctggtag
    37981 gtaaagtttg taatatcgga gatgaagccc caaatgaata cttgaaaaat ccgtctgatt
    38041 taatgagtat cactagtggc gatacagtac tggtcaaccc caaaggacgc ccagcctttg
    38101 aggctacttt caagttattc aatatctttt cagggaatta tatccccaat ggtggcaaca
    38161 agacaaaagg ctggtatcgt agaattatga ttgtcccttt taatgctgac tttaacgggg
    38221 agaaggaaaa gccttggatt aaaaatgaat ttttggccaa tgatgaagta ttagagtacg
    38281 cactttacaa agctatcaat caagagcctt ttacacactt tatcgaaccc aaagcagtca
    38341 aaggccttct agaagaatac caggaagaaa atgactactt gctttcatgg gttaaacatg
    38401 aatacatgga aagaggttgg catgagctgg acgtggtacc cgtttttata ctgaccagat
    38461 cactaaagca ctatgccgaa gatatgggaa tacccaaacc caatgtttac ggggctggta
    38521 aagaaactat caagcactta caacagttga cacctaatcg gtattctcta agaaagaaaa
    38581 gagttccttc agaagatttt gaaaaactag aggcatggga cgttgacaag ataaaaatgc
    38641 ggacacctca acactctatc actaaacaag aataagtgtg acgttctttt tttgcttaaa
    38701 cccttgataa tactgatttt cttaaaaaaa gtgtgacgtt gtgtgacgtt ctcaaaaaag
    38761 aaggtcacac cccttgaagc cttgatatat ctagctttag gggaataggt gtgacgttgt
    38821 gacattcttt ccaactctta tatatagaga aaaatgcagt atttatatat aggaacgata
    38881 aaacaaaaga acgtcacagg gtcacagggg tggtgaaaca cctagagcct caagggtttg
    38941 aacgtgtgac gttctttgtc acagaaggtc acagaacacg aaaaatatta cataatttac
    39001 cttaaaataa agaaatgaca acaacatgaa agttaaacta tttgaatata ctagacgatg
    39061 ggaaaaagaa gactttgaga aagagatcaa tgacttcatg gcaactgttg aagtgctgga
    39121 cgttaaattt tctggtacac catctagtga atcctttaat tcggtggcta tcgtattggt
    39181 attatacaga taacaaaatg gggtagatag taccgacccc cttgtaatgg tgtaactact
    39241 agtgacaccc ttaaaacaga aagaggaaaa acaacatgac attaaaaaca ttttcggata
    39301 aagccaaaac atttactttc acttacgaat ttaaagacct agatactgct atggtagcag
    39361 gtcacgcgct actgggatat atgactggga cttatgaagt accatctatt tcaataactc
    39421 acaaggataa agggacgctt gtcgctgagt atgtggaaga tcacaagcta aacaagactt
    39481 tcaagcgtat ttgtgacagt ttcaaagact attacaacca accagtggac gatgaagcat
    39541 ttgaagaacg ttataaacgg gagcgcgtgc tccaactcaa agagtcagag gactttgaga
    39601 acttgctgga aaaagtaaca gactacgagc tggaactatt agactatgct gatcgcttgc
    39661 tttctgataa gcctatccct atggactcta tgaccgcttt tggtacgttg gaaatgctgg
    39721 gcgatgaaag tattagccta ctccaaaagt tggacgtaga gggcgaatat aaaggccttg
    39781 ctggttatac agagcatttg aagtagaaca caggggagca atcccctttt tgttatcaag
    39841 tcaatagttt tgggtttttc catatagggg gaaataatga agcggttagc aatagaaaca
    39901 atcactaaac caatgaagct gagaggaata tctaagggta tagctgagtt ggacggtcaa
    39961 cgtttagaga ttgatttgga taatttaatg attgattttg gtggagagtc atttgaatta
    40021 gacagaatag caggaactaa gggaggtaat agatatttct ttctttgccc tgattgtggg
    40081 agacggtgca ggttgcttta taaacggtat ttatatttta gttgcggtac ttgtctagat
    40141 atccacaaga gcaccctgaa ccgtagtaaa acgaattgcc aatactactg ggagcttgca
    40201 ctaaaagaag ccagaaaggt agaaccaggg tggagtccta gacgtggtgg atatatgttt
    40261 gatagtttcc ctgaaagacc aaagtatatg aagcgcgaca ggtatcacaa gcactataag
    40321 aagtttttga agtatactaa aaaaggagat agattttggc tgaatggttt gagattgtag
    40381 gacaatatga agtagtgtgc aatttacaaa acaaacaaat actacatatt agacggtttg
    40441 aatgttaaaa aagctagata tgtcaaggat ttaagtaagt agagcgttcc aaaaaatggt
    40501 gcggtaagcg ttccgaaaaa tggtaaggtt ttggtaaggt tgcatatata aaaagtataa
    40561 gattagtata aggttgtgta ttttaaaata ctaaggtttt acaaaggtac agggcttttt
    40621 ttctagtgat ataaccacaa ggataccaca aggtagagag ttttaccgag ggttagaaaa
    40681 ggtgagattt tgcttaggta gtggcagtaa atatgcctga taaatggaat aaagatagtt
    40741 gtaagattag agtaagatgt tattagtaat ttgattagta gatacattta cctttctcta
    40801 agtgttatga tcaaattgaa ttagtcagta atcaacaata ctttgtgttg attgcattct
    40861 ttattgattg atataatcaa atcgataaca atagatgaat gaaatgcaat gttagcaata
    40921 gttaacaaat gatttctctt tctcttttat gtttgaatga catgagattg aactactgga
    40981 aaacgataag gggataaaaa agtatgcaaa tacccccctt atttttgaac gggggtatat
    41041 aatgttcgga tataggaacg cgcccccctt ctgtgcaaaa atttcccttt ttgaaatgtt
    41101 tttaattttt gtagaatgca gtattactaa gtgtttagct tgattttttg accgataaag
    41161 ctactccaat tttataacac agtggggcta tcttcctccc cacgcgcttc tatgaacttc
    41221 acactgtcat tgtacatttt ttctcacggg aaagcattga actccgagcg aacgccgaga
    41281 aagtggatat atcctcctat catttatcaa gcagataagg gcgacaataa gccttcttaa
    41341 ttgcttacaa aacgataggg agttaagacg aatttaaaag ctccttattt tcgtttttct
    41401 ccttgtcaaa tagtaaggaa ataagacagg aaataacatc gcttattttg attttgctcc
    41461 ctgaaaaact gtaaggagat aaggagactt attagcttcc ttaatttgga ttttctcctt
    41521 acaaaatgac agggaaataa gaactaaaat aactcccctt atttttctac aaaatgataa
    41581 gcagataagc caataaataa cttgccttaa ttgctttcaa acatgaacaa gtatgaacat
    41641 attccaccag tcgttgaaaa tacaaaaagc caaggcttac cacctcagaa tgattaggtt
    41701 ttggttaggt tttacattta aaaatagcaa ggtacaggac tttattctag agataaaata
    41761 ctaagatttc ctaagataca aatactttta gagataaaga acgttaagga gggtataatc
    41821 gaactcctag aaaacgcaaa aaaagccagc acagggctga cttctttata aattattcct
    41881 taaaattatt ataccataaa ggagtagcaa cttgactatt aaagaaatag aggaataact
    41941 aaaaagagta aagaaaggaa atgcccttat ccaggaattg caacttaaat accagagttt
    42001 agaaagtgga ctgcttgcag gatctagtca gtttcaaaca cgggtaagca caagcaaaac
    42061 caataccgct gaaaataaac tgcttgatac tttggaatta agagataaga tagcggagca
    42121 gatacaagct attattaatg aacgtatgga agcaatggat atgataaacc agttagaaga
    42181 aatcgaagaa tggttagtgt tggtaatgat atactttaat aatttaccta tggttaaaat
    42241 ctgcaatgat ttaaatttta gcaaggtaca gatttacaga attaggaaaa aagccattga
    42301 gaacttggcc aaggtgaaaa atgccaatcg ataaagaaga gacgataaaa caagcataca
    42361 aatttctaaa aagctatcac tcgttggtta aactgagcct aggcggtcaa gatggagcat
    42421 ttgaagccaa agcgatggag ctactgcgcg tgatcgaagc cttcagggac aatctggacg
    42481 atgtacgaca tgagatattc gccaatctct ttacaaggcg aactggggag aggttaaagc
    42541 tatggcagat atacgaggca ctagacattg ataaggctga gtatgagcgt ctcaaggctg
    42601 agatactgct agactttact aaaagctatt gtggtggtgt tttgttgaaa aaatgttgag
    42661 atttaagcga gagaacatgg acatttatgg acacatatcg ccagttgttg aacagctcat
    42721 aaaatgttgt caggtactaa caagttctta cacatcccgc ccgtcgtcga aaaactaaaa
    42781 aataatctct gggtctgaaa agttcctaca tattccacca gaacggagag ttagaagcgt
    42841 aaatgttggc aaatgtaggc tgaggcttct tattcgcccc ctattttgct ttgtttcgta
    42901 ctggacaact aaaacaccat ggataaacta caagccctca gaaacgaatc tgggggcttt
    42961 tgtgaggtca taatcttata aaccacgcgc ttcatggtat aatataccta tcagcaacca
    43021 gcaataaaaa aagcacgttt gaccgtgcta gtttcttgcc tgctgaactc gtcaaatctt
    43081 agcccttttg tggggctttt tttgctcccc tttttgcgta ctttggggga gcaagtagta
    43141 aaaagtaatg ttagtaattt ttattaaaaa gcgcgtgata taagggttag gaagtcctaa
    43201 ggaaacataa aataagaagt tttttattat actacaaaat cggccttttg ggtaatagaa
    43261 tctcactttt tttggtataa tggtaagcaa taatggacta gaaagaacaa agatgcaaga
    43321 taaaattgtc attcatgggg cgcgtgccca taatttaaaa aatattgatg tggagattcc
    43381 gcgagacaag ttggttgtcg tgactggctt gtcaggttca gggaagtcca gtctggcttt
    43441 tgataccctc tatgcggagg gacaacgtcg ctatgtagag agtttgtccg cctacgctcg
    43501 tcagttcttg ggaaatatgg aaaaaccaga tgtagatgcc attgatggtc tcagcccagc
    43561 tatttctatc gaccagaaaa cgactagcaa aaaccctcgc tcgacggtgg gaacaacgac
    43621 tgaaatcaat gactatctgc gtctcctcta cgcgcgtgtg gggacgcctt actgtatcaa
    43681 cgggcatggg gctatcaagg cttcttctgt ggagcaaatc gttgataagg ttttggagtt
    43741 acctgaacgc cagcgcctgc agattttggc ccctgtcatc cgtaagaaaa aaggacagca
    43801 taagagcgtt atcgagaaga ttcagaaaga tgggtatgtt cgtgtccgtg tggatgggga
    43861 agtctatgat gtgaccgaag tgctagagtt gtccaagagc agacaacaca atattgatgt
    43921 cgtggttgac cgtattgtta tcaaggaggg cattcgtagt cgtctctttg attccattga
    43981 ggctgccctt cgtatcgcag aaggttatgt gattatcgac accatggacg actctgagtt
    44041 gttgttctct gagcattatg cctgtccagt ttgtggattt actgtcccag agttagaacc
    44101 tcgtctcttc tctttcaatg ctccctttgg ctcttgtagt gagtgtgacg gcttggggat
    44161 taagctggag gtggatactg atttggtagt gccagatgcc agcaaaacct tacatgaggg
    44221 agcgctggca ccttggaatc ctatctcatc caactactat ccaaacatgt tagagcaggc
    44281 catgaaagtc tttggagtgg ctatggataa gccttttgag gacctgtcag aagaagataa
    44341 gaacttgatt ctctacggct cagatggtaa ggaattccat ttccattatg aaaatgaatt
    44401 tggtggtgtg cgcgatatcg acattccgtt tgagggagtt atcaataata tcaaacgtcg
    44461 ttaccatgaa accaatagcg attacactcg cactcagatg cgtctctaca tgaatgagct
    44521 gacctgcgga acctgtcaag gctatcgtct caatgaccag gccttgtctg tccgtgtggg
    44581 cggccagcaa gggccacata ttggagaaat ctcagacctg tctatcgctg accacttgga
    44641 cttggtgagc cagttaactt tgtctgaaaa tgaagccatc attgctcgtc ccattctcaa
    44701 ggaaatcaag gatcgtttga ccttccttaa taatgtgggt cttaactatc taaccctgtc
    44761 acgttcagca ggaacccttt caggtgggga aagtcagcgc attcgtttgg caacccagat
    44821 tggttccaac ctatcaggtg tcctctatat cctagacgag ccgtcaatcg gtcttcacca
    44881 gagagacaat gaccgcctga ttgccagtct gaaaaagatg cgtgacttgg gcaatactct
    44941 tatcgtggtg gaacacgacg aagataccat gcgtgaagct gattatctga ttgacgttgg
    45001 tcctggtgcc ggtgtttttg gtggtgagat tgttgcagca ggtacaccta agcaagtggc
    45061 tcgcaacagc aagtctatca caggtcagta cttgtcaggc aaacgtgtca tcccagtacc
    45121 agaagagcgc cgtgtcggaa atggtcgttt tattgaagtg ataggagcgc gtgagaacaa
    45181 cttgcaaaat gtcacggctc gctttccact aggaaaattt atcgcagtga caggtgtgtc
    45241 gggttcaggg aaatcgactc taatcaacag cattctcaaa aaagccattg cccagaagct
    45301 caaccgtaat tcagacaaac ctggtaagtt taagactatt acagggattg agcatgtcga
    45361 ccgtttgatt gatattgacc agagccctat cggacggacg ccgaggtcta acccagctac
    45421 ctatacagga gtttttgacg atatacgtga cctttttgct cagacaaatg aagccaagat
    45481 tcgaggctac aagaaggggc gcttcagttt caacgtcaag ggaggtcgct gtgaagcttg
    45541 ctcaggtgac gggattatca agattgagat gcacttcttg ccagatgttt atgtggcttg
    45601 tgaagtttgc cacggaaccc gctataacag tgaaacccta gaagttcact acaaggaaaa
    45661 gaatatttcg caggtcttgg atatgacggt caacgatgcg gtagaatttt tccaacacat
    45721 tccgaaaatt caacgcaaac tccagaccat caaggatgta gggctaggct atgtgacctt
    45781 gggacagcca gctaccaccc tttctggggg agaagcccaa cgtatgaagt tagctagcga
    45841 actccacaaa cgctcgacag gaaaatcttt ctacattctg gatgagccga cgacagggct
    45901 tcatacagag gacattgctc gcctgctcaa ggttttagct cgctttgtag acgatggcaa
    45961 tacagtcctc gtcatcgagc acaatctgga tgttatcaag acggcagacc atatcattga
    46021 cttgggacct gagggcggtg tcggtggtgg aaccatcatc gtaacaggaa ctccagaaga
    46081 agtagctgcc aacgaagcca gctatacagg acactatttg aaaggaaagt tacatcatga
    46141 ataaacgcgt acaagcattt ctagctaaaa tgcaagaaaa agaactagat ggtatcatca
    46201 tcaacaatct taaaaacgtc tattatttga ctggtttttg gggctcaaac ggaacagtct
    46261 ttatcagccg tgaccgtcag gtcttagtga cagactctcg ctatatcatc gcagctaagc
    46321 aagaaaccag tggttttgag attgtggctg atcgtgatga attggctgtc attgcaggaa
    46381 ttgttaagga catgggcttg actcgtatcg gttttgaaga tgagatttca gtatcttatt
    46441 accaccgtat gcaggcagct tttgcaggtt tggacttgct tccacaaact caatttgtgg
    46501 aaggtcttcg tatgattaag gatgaggcag agattgcagc gattcgcaag gcttgttcta
    46561 tctcagacca agctttccgc gatgcgcttg actttatcaa accaggaaaa actgagattg
    46621 aaattgccaa cttccttgat ttccgcatgc gtgagttggg agcatctagc ttatcttttg
    46681 atacgatcct agctagcggt atcaattctt ctaaacccca tgcccatcca atgcacaaac
    46741 cagtggagtt gggagaagcc attaccatgg acttcggctg tctctatgac cactatgtca
    46801 gtgatatgac ccggactatc tatctagggc atgttagcga tgagcaggca gagatttaca
    46861 atacggttct aaaagctaac caagccttga ttgaccaagc taaggcaggc ttaggtttcc
    46921 gtgactttga caaaatccct cgtgatatta tcattgaggc aggttatggc gactacttta
    46981 ctcacggcat tggccacggt attggtctgg atatccatga ggaaccctac tttagccaga
    47041 cttctacaga aactattaag acaggtatgg ccttgaccga tgaaccaggt atctatatcg
    47101 aaggcaaata tggcgttcgt atcgaggatg atatcctgat tacagagaca ggttgtgaat
    47161 tattgaccct agctccaaaa gagttgatag tcatttagtt gtttgtcaag aaaaaagtac
    47221 gaaaatgacg aaaaaagtca aaaaaaatta aaaataggtc gcaagtcgga tgttttttat
    47281 ggtataatag actaaactga tagtaacatg tagcgaaagg ggtaggtaca tgattaaaat
    47341 ttatacagtc tcaagttgta ctagctgtaa aaaagcaaaa acctggctca atgcccacca
    47401 gttaagttat aaagaacaaa accttggtaa agaaggaatt acgagagaag aattactgga
    47461 tattctaacc aaaacagata acggaatagc cagcatcgtt tcgtctaaaa atcgctatgc
    47521 caaagccctt ggagtggata ttgaagattt gagtgtcaat gaagttctca atctgattat
    47581 ggaaacaccg agaattttaa agagcccaat ccttgtagat gaaaaacgcc tgcaagttgg
    47641 ctacaaggaa gacgatattc gtgccttcct accacgctct gtccgtaatg tagaaaatgc
    47701 agaagcacgt ttgcgtgcag ctctataaac atcaaggctg ggagcacttc ccagtcttat
    47761 tctattttaa tttcaaaaag aaagaagaaa gaaatgaaaa aaatagttct tgttagtcta
    47821 gctttccttt ttgtcctggt tggttgcgga cagaaaaaag aaactggacc agctacaaaa
    47881 acagaaaaag atacgcttca gtcggcattg ccagttattg aaaatgctga gaagaataca
    47941 gttgtaacta agactttggt cttgcccaag tcagatgatg gtagccagca aactcaaacc
    48001 attacataca aggacaagac ttttttgagc ttaacgattc aacaaaaacg tccagtttct
    48061 gatgagttga agacttatat cgaccaacat ggagtggaag aaactcaaaa agctcttctt
    48121 gaagcggagg agaaggataa gtctatcatt gaagctcgta aattggcagg tttcaaactt
    48181 gaaacaaaac tattgagcgc aacggaactt caaacaacga ctagttttga ttttcaagtt
    48241 ctggatgtca agaaggcttc ccagttggaa catctgaaga atattggttt tgaaaatctt
    48301 ttgaaaaatg aaccaagcaa atatatttca gatagattgg caaatggcgc gacagaacaa
    48361 tagaaaatcc aaataaatag actgcctgaa ttgtagaagg taaggaatta tgctataatg
    48421 gtactattct aaggaaagag ggtgttagaa tgggatttac tgaagaaaca gtacgtttta
    48481 aattggacga ttccaataaa aaagaaatta gcgaaacttt gacagatgtt tatgcttcgt
    48541 tgaacgataa gggttacaac ccaattaacc aaatcgtagg ttacgtattg agtggagacc
    48601 ctgcctacgt tcctcgttat aataatgcac gaaatcaaat ccgtaagtat gagcgtgatg
    48661 aaatcgttga ggaattggtt cgttactacc tcaaaggaca aggagtcgat ctataaccta
    48721 tgagaattat gggattggac gtcggttcaa aaacggtagg ggtggcgatt agcgatccgc
    48781 ttggttttac agctcaaggg cttgaaatca tccagataaa tgaagaacaa ggccaatttg
    48841 gttttgaccg cgttaaggaa ttggttgata cttacaaggt ggaacgattt gtagtgggct
    48901 tgcctaaaaa catgaacaat acaagtggac cgcgcgtgga agctagtcaa gcatacggag
    48961 caaagctaga agagtttttt ggtttaccag tagactatca ggatgaacgc ttgacaacag
    49021 tggctgctga gcgcatgttg attgaacaag cagatatcag tcgcaataag cgcaagaaag
    49081 tcattgataa gttagcagct cagctgattt tacaaaatta tttagataga aaattttaat
    49141 ataaaggaga ggctatgtca cacgatcata accacgacca cgaagaacgt gaactaatca
    49201 cactagtaga tgagcaagga aatgaaacct tgtttgaaat ccttttgaca attgatggaa
    49261 aagaagaatt tggtaaaaac tatgttcttc tagtaccagt taacgcagaa gaagacgaag
    49321 acggacaagt tgaaatccaa gcttactcat tcatcgaaaa cgaagatgga acagaaggcg
    49381 aattgcaacc aatcccagaa gactcagaag acgaatggaa catgattgaa gaagtcttca
    49441 acagctttat ggaggagtga tacagtctgg gagactgtat cagcccaact cccagaaatg
    49501 gggaagagtt ggaacgtcca gtggatgttt ttagcccata ttcacattca tagtagctag
    49561 ttattagcta accaggtaag aggtcgggac gaaaatcctg gccttgtttt tattagtaac
    49621 catactttaa tgcgataatt gattggactt ttgtcaagga gatgtgtatg tttgaagtag
    49681 aagaatggct ccatagtcgg attggtttga attttcgatc aggtttgggt cgaatgcagc
    49741 aagcggtgga tttgttagga aatcctgagc agtcttaccc tattatccac gtaacaggga
    49801 ctaatgggaa aggatctacc attgctttta tgagggaatt atttatgggg catggcaaaa
    49861 aagttgcgac ctttacctcc cctcatatcg tctctatcaa tgaccgaatc tgcattaatg
    49921 ggcagcctat agcagacgca gactttatcc gtttgactga tcaggtcaag gagatggaga
    49981 aaacgcttct gcaaactcct gcccagttgt ccttttttga attgctgacc ttggttgctt
    50041 ttctttattt tagggagcag gaggtggatt tggttttatt agaagtggga attggtggct
    50101 tacttgacac gaccaatgtg gtaactggag agcttgctgt catcacctcc attgggcttg
    50161 accatcaaga aaccttgggt gatagtctag aagcaattgc agagcagaaa gctggtattt
    50221 tcaaggctgg taagaaggca gtgattgcga aattgcctcc agaagctagg cttgcctgtc
    50281 agaaaaaagc cgaatcttta gctgttaacc tttatcaggc aggtcaagat tttttaatgc
    50341 tgaatggtga tttttcaagc tctttactaa atctttcaca gctgaacata ggcttagaag
    50401 gagtctatca gcaggagaat gcagccttgg cgttgcaaac ttttcttctt tttatgagag
    50461 aaagaaagga agctgttgat gaacaggctg taagaaaggc cttggaacag acccattggg
    50521 ctggtcgctt ggagcgtatt cgcccacaga tttatttgga tggtgctcat aacctccctg
    50581 ccttgactcg cttggctgag tttatcaaag aaaaagagca ggaaggctat cgacctcaaa
    50641 tcctctttgg atccttgaaa cgtaaggatt atcaagggat gttgggttat ctgactgaaa
    50701 aattgcctca ggtggaactc aaggtgaccg gctttgacta tcagggggct ttggacgaaa
    50761 gggatgtgac aggttacgat atagtttctt cttaccgaga atttatcagc gattttgaag
    50821 aaagggcaga cgctcaagac ttgctgttcg ttacagggtc tctctatttt atctcagaag
    50881 tacggggcta cctgctggac cgtgagcaga taaattgact ccattttttg aacttgttat
    50941 actaggggaa ttgctggtta gagaaaattt ctctaaattg gtagcagaaa ggaaattcat
    51001 catgaaatta aaaagattca cactttctct tgcttctcta gcaagtttta gtctcttagt
    51061 agcttgttca caaagagctc aacaggttca acagcctgtt gctcagcagg tccaacagcc
    51121 tgctcaacag aataccaata ctgcaaatgc aggaggtaac caaaatcaag cggctccagt
    51181 acaaaaccaa cctgttgctc aaccgaccga tattgatggg acttatactg gtcaggatga
    51241 cggagaccgt atcactttag tggtaactgg aacgactggt acatggactg agctcgaatc
    51301 tgacggggat cagaaagtca aacaggttac attggattca gcaaatcaac gcatgattat
    51361 tggcgatgat gtcaaaattt acactgtaaa cggtaatcaa attgtcgtag atgatatgga
    51421 tagagaccca tcggaccaaa tcgttttaac taaataagac tatgcaagta gaaagggctg
    51481 gatttttcag cctttttact tttacctaga aaataatcat aaatacttgc cttctaccga
    51541 atacctgcgt tatactagta tcaattactt gtttttagca ttcaaactat caaggagggg
    51601 atatgaaata taggaaattt caattattga tgtccaagta tggctttagt ctttcgatta
    51661 tgctacttga actttgtctt gtttttggtc tctttcttta tttaggacgc atggctccca
    51721 ttttatggat tactgtcctc attctactga gtatcatcac aatcatttcg atagtcaacc
    51781 gtaatacgac tcctgagaat aaggtaacct ggttgttagt agcctttgtg ccagtatttg
    51841 gtcccttgct ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa atcaaacaac
    51901 tgaagaagct aggctctatg catttccaag aagcaaatag ccagctacta aaagagaaat
    51961 taaaagaaag tgacaaggca gcttatggag tcatcaagtc cttattgagt atggatacca
    52021 atgctgacat ctatgatcaa actgcctcta cattttttcc taacggagaa gctatgtgga
    52081 aaaagatggt agaagatctt aaaaaggctg agaaatttat tttcttggaa tattacatta
    52141 tagaagaagg tttgatgtgg aatcgcatac tagatatact agagcaaaag gtagctcagg
    52201 gtgtagaggt taagatgctc tatgatgata tcggctgtat ggctacttta acaggagatt
    52261 atgcacatcg acttcgtcag ctgggcatcg aggcccataa attcaataaa gttattcctc
    52321 gtttgacagt ggcttataat aacagagatc atagaaaaat attgattgtt gatggtcaga
    52381 tagcctatac tggtggggtc aatctggcag atgagtacat taaccacgtc gagagatttg
    52441 gttattggaa ggatagtgga attcgcttag acggactagc agtaaaagcc ctgacacgct
    52501 tatttttgac cacttggtac attaatcgag gagaaattag tgattttgat caatatcatt
    52561 tagaaaatca ttctatcccg agtgacggtt taaccattcc atacggaagt ggacccaagc
    52621 caatttttcg agcgcaggta gggaaaaaag tttatcagag tttaatcaat caagcaacag
    52681 aatcggtcta tattacgaca ccttatttga ttatagatta tgatttaaca gagacaatca
    52741 aaaatgcagc tatgagaggg gtcgatgttc gaattatcac cccttacata ccagataaga
    52801 agttcattca gttagtcacg agaggagctt atcccgacct tctttctgct ggtgttcgga
    52861 tttatgagta tagtccaggt tttattcata gtaagcagat gttggtagac gaagattttg
    52921 cggtggtggg gacaatcaat ctcgactacc ggagcttggt acaccattat gaaaatgcag
    52981 tcttactcta taaaactcct tctataaggg aaatcgcccg agattttcga aatatatttg
    53041 cagattctca ggaagtctat cctcattcta tcaaaacgag ctggtatcaa aagcttgtaa
    53101 aagaaatcgc ccagctattc gcccctatct tataagaaat ctagaactta ggatacaaac
    53161 cagacctatt tttcttgtct tttacgaata gaaagaaaga ggaggggaat tcatgctaac
    53221 taaggaagaa gtgaatgata tgattgagtt caaacagaca catttacacc gctttcggga
    53281 aattgaaacc tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc aagctgacaa
    53341 tcctaggact ttttgatata ctaagacaga taaattgaac aggagaaacg atatgagtgt
    53401 gtatggtaga gtagaagaag ttcataagga gaatcgtgaa cctctagaat accaaatcga
    53461 acaagaatcg catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt tactatggag
    53521 tacgcttgta acggggataa ctctaggagt accgctatta ctcgacttaa tgagtgcaca
    53581 agaagtgcag gatttttatg caggttgggc gcttcatcag acagggaaga tttacagcaa
    53641 ctattatgga agtcaaggtt tgctttatta tttgctgact tacgtgagtc agggcggatt
    53701 tttctttgcc atctttgagt ggttagcctt ggtagcagga ggatttttcc tttttagatc
    53761 agcggacacc ttgacagagc aaggagacca agctggacat ctggtgacta ttttttacat
    53821 gctagttaca ggtcttgctt ttggtggagg ctatgcgact cttttagcgc ttcctttctt
    53881 attcgcagcc tttagtttag ttgcggctta cctaagcaat ccaagccatg ataagggatt
    53941 tgtacggatt gggctagctt tggcaggcgg atttttcttt gctcccttat catcgctcct
    54001 gtttattgct gtagtgagtt taggcttgtt ggtctttaac cttgggcata gacgctttgc
    54061 gcatgggttt tatcagtttc ttgcagtggc tttaggtttt tcacttgtct tttatccaac
    54121 tgcctactat agtgctgcaa caggaagttt tggggatgcg attagtggta ttcgttatcc
    54181 tattgacagt attcgctttg attttacttc taaaatttta gagaatatgt ttttttatgg
    54241 cttgttgtcc cttggtttgg gatttgtggt ttgtatcttt ttaggtctct ttcaatccaa
    54301 accctttaaa ctatacgtca tttcggttcc tgcaagtctt gtggtaattt taggtttgat
    54361 tttacttttc ttttcacaag agcctctgca cgcttcttat ttgatggtcg tcttccctgt
    54421 tttcctactt ttattggtaa ccaatattaa gagtcaacag agggggcgta gtgctagaag
    54481 aagccgaaga gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa atctatatct
    54541 gctagttttt gggtttgtct atcttttgtc tgttcctttt ttgatgaagt ttgtccttta
    54601 tccagtacct tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg agacaaatac
    54661 ggaagatgct atctatgcat gggatgatac tgcgactctt tatcgtaaga gtgagcgctt
    54721 gtcgccatcg gcgattttgt ccccgttgca ctatacagca actgaggaaa atcgtaataa
    54781 gttacttaat gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg acaaggtgga
    54841 agtctggtct gaagtggaaa cactcttaaa agaaaattac caacaagtaa agactgatta
    54901 ctcagagttt aaagtctata aaattaaata accaaatcaa tatcttgtgt atttttaaaa
    54961 attttaagat ttttaacaca agatattgat ttttcttttt agagtggtat aatacttttt
    55021 agaaagaaca ttttagaaaa gagcatgcgt atgattgcac tagaagaaaa aattacaatt
    55081 ttgccaactc tcttcgtcga gaaacgagat gggagacgtg ttgtatttga tgtggacaag
    55141 attgacaagg ctctccacaa ggcggctgac aaggttatgg atgtgacacc cctggttgaa
    55201 aaacgcctca atgatctgac tgagcgaatt attacagaaa ttcatagtcg ctttccacag
    55261 ggaattaaga tttacgaaat tcaaaatatc gtagaacatg aactccttga agccaaagaa
    55321 tatgcgctgg ctgaggagta tattacttat cggacacaga gggattttga gcgctcaaaa
    55381 gcgacggata tcaactttag tattcataaa cttctcaaca aagaccagac agttgtcaat
    55441 gaaaatgcta ataaagacag tgatgtcttt aacactcagc gtgatttgac agcagggatt
    55501 gttgggaaat caatcggact gcaaatgctt cctaagcacg tagccaatgc ccaccaaaag
    55561 ggggatatcc actatcacga tttggactac agtccctata cccctatgac caactgctgt
    55621 ttgattgatt ttaagggtat gttggaaaat ggttttaaga ttggaaatgc agaggtagag
    55681 agtcccaagt ctatccagac tgcgacagca cagatttctc aaatcattgc caacgttgct
    55741 tctagccagt acggtggctg ttcagctgac cgtatcgatg aaattttggc gccttatgca
    55801 gagaagaact atcaaaaaca tctcaaagat gcagaagagt gggtattgcc tgaaaaacgg
    55861 gaagattacg cttggaagaa aacgcaaaag gacatctacg atgccatgca atctcttgag
    55921 tatgaaatca atactctctt tacttcaaat ggacaaacac cttttacttc gctaggtttt
    55981 ggtctgggaa ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa cattcgcatc
    56041 aagggtcttg gttcagaaca ccgtacggct atctttccta aacttatttt cactctgaaa
    56101 agaggcctta atttagagga aggaactccc aactacgaca tcaagcagtt ggctcttgag
    56161 tgtgcaacca aacggatgta tccagatgtt ttatcttacg ataagattgt tgacttgaca
    56221 ggatccttca aggtgcctat gggttgccgt tctttcctcc aaggatggaa ggatgaaaat
    56281 ggtgtagaag tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa tctgcctcgt
    56341 attgctcttg agtctgaagg tgatatgaat aagttctggg aaatcttcaa cgagcgaatg
    56401 aatatcgcag aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc gacaccagcg
    56461 aatgctccta tcctttatca gtacggtgct tttggccatc gtctaggtaa agaagaaagt
    56521 gttgaccagc tctttaagaa tcgtcgtgcg accgtttcgc tgggctatat cggcttgtat
    56581 gaagtagcga cagttttctt tggtaacagc tgggaaagta atccagatgc taaggaattc
    56641 acgctagaca tcattcacga tatgaaacgc cgtgtagaag agtggtcaaa ccaatatggc
    56701 taccatttct ctatctactc aacaccatcc gaaagtctga cagaccgttt ctgccgacta
    56761 gatatagaca agtttggctc tattcctgat atcacagaca aggaatacta caccaactct
    56821 ttccactacg atgttcgtaa aaatccaaca ccgtttgaaa aattggactt tgagaaagtc
    56881 tatccagaag caggtgcgtc aggtggtttc atccattatt gtgagtatcc agtccttcag
    56941 caaaatccaa aggccttgga agctgtctgg gattatgctt atgaccgtgt aggctatcta
    57001 ggcaccaata ctccgattga ccgttgctac aagtgtgact ttgaagggga ttttgaacca
    57061 actgagagag ggtttgcttg tccaaactgt ggcaatagcg accctaaaac agtagatgtg
    57121 gtgaagcgaa cttgtggcta cctaggtaat cctcaagcaa gaccgatggt caacgggcgt
    57181 cacaaggaaa tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa aatagctggg
    57241 catcaagtaa caaattagaa agaaatgaaa tgggaaaata tcaactagac gataaggggc
    57301 gcgcacaagt gacccgttat cacgagaaac actctaaagg tggagctggt aagaaagaac
    57361 gcttgcttag cttcagagaa caatttttaa acaagaacaa gaaaaaataa aagtgagagc
    57421 cagctctcgc ttttctcata gtgggaggta aggatggaat tacgcagacc aagattagcg
    57481 gataagaaag ctgttttaga tatgatgaca gagtttgaaa aatttcagtc gcctcacgac
    57541 ggcggtttct gggatacaga gaactttgtg tatgaagact ggttagaaag caatcaggaa
    57601 caggaaatgg ggattaatct gcctgaagga tgggttcctg caattcagtt agtggctttt
    57661 tctgagaaag gtcaagcagt tggatttctt aatctccggt tgcgcctcag taactttcta
    57721 ctagaagaag gtggccacat tggctactcc attcgtccat ctgaaagagg caagggttat
    57781 gcaaaagaga ctctccgtca gggcttgcaa gttgctaagg aaaagaacat caagaaagct
    57841 ctggtgacct gtagcgtgaa taatcctgct agcagagcag ccattctagc aaatggtgga
    57901 atatttgagg atgctcgcaa tggagtcgag cgttattgga tagaggtagc gaatgaataa
    57961 tccaaaacca caagaatgga aaagcgagga acttagtcaa ggtcgtatca ttgactacaa
    58021 ggcctttaac tttgtggacg gcgaaggcgt gcgcaactct ctctatgtat caggctgtat
    58081 gtttcactgc gagggatgtt ataatgttgc gacttggtct tttaatgctg gcattcccta
    58141 tacagcagaa ttagaagagc agattatggc agaccttgcc caaccctatg ttcaaggctt
    58201 gactttgctg ggaggggagc cttttctcaa tactggcatt ctcttgcctc tagttaaacg
    58261 catccgaaag gaattgccag acaaggacat ttggtcctgg acgggctaca cttgggaaga
    58321 aatgatgttg gaaactccag ataaactgga actcttgtca ctgattgaca ttcttgtcga
    58381 tggacgatac gatcgaacta agagaaatct catgctccag tttcgaggtt cgtccaacca
    58441 acgaattatc gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt gggacaagct
    58501 caatgacgga aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa ggacttagta
    58561 gaccaactag tctcagagat cgagacgggg aaagtcagga cactgggaat atacggtcat
    58621 ggagcttcag gtaaatcaac ctttgcacag gaattgtacc aagctttaga ttctactaca
    58681 gtaaatttgc tagagacaga tccttatatc acctcaggac gccatctggt agtacccaag
    58741 gacgcgccga atcaaaaggt gacagccagt ctgccagtgg cgcatgaact ggagagtttg
    58801 cagagagata tccttgcctt gcaggcgggt atggatgtct tgacaattga agaaccttgg
    58861 aaggctagtg aggtcttgtc tggagccaaa ccaattttga ttgtcgaagg gatgtctgtt
    58921 ggctttctac ccaaggaact ctttgaaaaa ccatctgttt ctacacggat gaggagaccg
    58981 aattaaagcg acgccttgct agagatacga ctgtgagaaa tcgcgatgca tcctttatat
    59041 tggctagcca tcagatgaga cgggagcagt atctgcgata ctataaagaa actgagtcta
    59101 aggcggatat cttagtggac caatcagaag ataaatttga tgtcaagagg acttaactat
    59161 agaagaaata tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    59221 cccaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggcttt gtgttattct
    59281 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    59341 gcattgccac gcaacaccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    59401 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    59461 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    59521 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    59581 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    59641 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    59701 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    59761 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    59821 cactgtgtca gtttcctatt ttcacgttga gtttgacgcc ctttgtatct tagacttgag
    59881 cataaaaaac gctcgttaaa aactttttga ataaaaatat agaaaaggaa ctattttctc
    59941 atgacaaaag gaatcttagg gaaaaaagtg ggaatgactc aaatcttcac tgaagctggc
    60001 gaattgatcc ctgtaacagt tattgaagca actccaaacg ttgttcttca agttaaaact
    60061 gttgaaacag acggatacaa cgctatccaa gttggtttcg atgacaaacg cgaagtattg
    60121 agcaacaaac ctgctaaagg acatgtagcg aaagctaaca cggctcctaa gcgcttcatt
    60181 cgtgaattca aaaacgttga aggcttggaa gttggtgctg aaattacagt tgaaacattc
    60241 gcagctggag acgttgttga cgtaactggt acttctaaag gtaaaggttt ccaaggtgtt
    60301 atcaaacgcc acggacaatc acgtggacca atggctcacg gttctcgtta ccaccgtcgt
    60361 ccaggttcta tgggacctgt tgcacctaac cgcgtattca aaggtaaaaa ccttgcagga
    60421 cgtatgggtg gtgaccgcgt aacaattcaa aatcttgaag ttgtacaagt tgttccagaa
    60481 aagaacgtta tccttatcaa aggtaacgta ccaggtgcta agaaatctct tatcactatc
    60541 aaatcagcag ttaaagctgg taaataataa agaaagggga aatcagtcac aatggcaaac
    60601 gtaacattat ttgaccaaac tggtaaagaa gctggccaag ttgttcttag cgatgcagta
    60661 tttggtatcg aaccaaatga atcagttgtg tttgatgtaa tcatcagcca acgcgcaagc
    60721 cttcgtcaag gaacacacgc tgttaaaaac cgctctgcag tatcaggtgg tggacgcaaa
    60781 ccatggcgtc aaaaaggaac tggacgtgct cgtcaaggtt ctatccgctc accacaatgg
    60841 cgtggtggtg gtgttgtctt cggaccaact ccacgttcat acggctacaa acttccacaa
    60901 aaagttcgtc gcctagctct taaatcagtt tactctgaaa aagttgctga aaacaaattc
    60961 gtagctgtag acgctctttc atttacagct ccaaaaactg ctgaatttgc aaaagttctt
    61021 gcagcattga gcatcgattc taaagttctt gttatccttg aagaaggaaa tgaattcgca
    61081 gctctttcag ctcgtaacct tccaaacgtg aaagttgcaa ctgctacaac tgcaagtgtt
    61141 cttgacatcg caaatagcga caaacttctt gtcacacaag cagctatctc taaaatcgag
    61201 gaggttcttg cataatgaat ttgtatgatg ttatcaaaaa acctgtcatc actgaaagct
    61261 caatggctca acttgaagca gggaaatatg tatttgaagt tgacactcgt gcacacaaac
    61321 ttttgatcaa gcaagctgtt gaagctgctt tcgaaggtgt taaagttgcc aatgttaaca
    61381 caatcaacgt aaaaccaaaa gctaaacgtg ttggacgtta cactggtttt actaacaaaa
    61441 ctaaaaaagc tatcatcaca cttacagctg attctaaagc aatcgagttg tttgctgctg
    61501 aagctgaata atctaaggag gaaatatcgt gggaattcgt gtttataaac caacaacaaa
    61561 cggtcgccgt aatatgactt ctttggattt cgctgaaatc acaacaagca ctcctgaaaa
    61621 atcattgctt gttgcattga agagcaaggc tggtcgtaac aacaacggtc gtatcacagt
    61681 tcgtcaccaa ggtggtggac acaaacgttt ctaccgtttg gttgacttca aacgtaataa
    61741 agacaacgtt gaagcagttg ttaaaacaat cgagtacgat ccaaaccgtt ctgcaaacat
    61801 cgctcttgta cactacactg acggtgtgaa agcatacatc atcgctccaa aaggtcttga
    61861 agtaggtcaa cgtatcgttt caggtccaga agcagatatc aaagtcggaa acgctcttcc
    61921 acttgctaac atcccagttg gtactttgat tcacaacatc gagttgaaac caggtcgtgg
    61981 tggtgaattg gtacgtgctg ctggtgcatc tgctcaagta ttgggttctg aaggtaaata
    62041 cgttcttgtt cgtcttcaat caggtgaagt tcgtatgatt cttggaactt gccgtgctac
    62101 agttggtgtt gtcggaaacg aacaacatgg acttgtaaac cttggtaaag caggacgtag
    62161 ccgttggaaa ggtatccgcc caacagttcg tggttctgta atgaacccta acgatcaccc
    62221 acacggtggt ggtgaaggta aggcaccagt tggtcgtaaa gcaccatcta ctccatgggg
    62281 caaacctgct cttggtctta aaactcgtaa caagaaagcg aaatctgaca aacttatcgt
    62341 tcgtcgtcgc aacgagaaat aatattaaac tagtcgctta agcaactagt aaatccgcca
    62401 gctcggtagc gctccatagg agtgcaagcc gctgtggtac aacatttaaa ggagaaaata
    62461 taaaaatggg acgcagtctt aaaaaaggac ctttcgtcga tgagcatttg atgaaaaaag
    62521 ttgaagctca agctaacgac gaaaagaaaa aagttattaa aacttggtca cgtcgatcaa
    62581 cgatcttccc aagtttcatt ggttacacta ttgcagttta tgacggacgt aaacacgtac
    62641 ctgtttacat ccaagaagac atggtaggcc acaaacttgg tgaatttgca ccaactcgta
    62701 cttacaaagg tcacgctgca gacgacaaga aaacacgtag aaaataagga gaacataaat
    62761 ggcagaaatt acttcagcta aagcaatggc tcgtacagta cgtgtttcac ctcgtaaatc
    62821 acgtcttgtt cttgataaca tccgtggtaa aagcgtagcc gatgcaatcg caatcttgac
    62881 attcactcca aacaaagctg ctgaaatcat cttgaaagtt ttgaactcag ctgtagctaa
    62941 cgctgaaaac aactttggtt tggataaagc taacttggta gtatctgaag cattcgcaaa
    63001 cgaaggacca actatgaaac gtttccgtcc acgtgcgaaa ggttcagctt caccaatcaa
    63061 caaacgtaca gctcacatca ctgtagctgt tgcagaaaaa taaggaggta aaatcgtggg
    63121 tcaaaaagta catccaattg gtatgcgtgt cggcatcatc cgtgattggg atgccaaatg
    63181 gtatgctgaa aaagaatacg cggattacct tcatgaagat cttgcaatcc gtaaattcgt
    63241 tcaaaaagaa cttgctgacg cagcagtttc aactattgaa atcgaacgcg cagtaaacaa
    63301 agttaacgtt tcacttcaca ctgctaaacc aggtatggtt atcggtaaag gtggtgctaa
    63361 cgttgatgca ctccgtgcaa aacttaacaa attgactgga aaacaagtac acatcaacat
    63421 catcgaaatc aaacaacctg atttggatgc tcaccttgta ggtgaaggaa ttgctcgtca
    63481 attggagcaa cgtgttgctt tccgtcgtgc acaaaaacaa gcaatccaac gtgcaatgcg
    63541 tgctggagct aaaggaatca aaactcaagt atcaggtcgt ttgaacggtg cagatatcgc
    63601 ccgtgctgaa ggatactctg aaggaactgt tccgcttcac acacttcgtg cagatatcga
    63661 ttacgcttgg gaagaagcag atactacata cggtaaactt ggtgttaaag tatggatcta
    63721 ccgtggtgaa gttcttccag ctcgtaaaaa cactaaagga ggtaaataac caatgttagt
    63781 acctaaacgt gttaaacacc gtcgtgagtt ccgtggaaaa atgcgcggtg aagcaaaagg
    63841 tggaaaagaa gtagcattcg gtgaatacgg tcttcaagct acaactagcc actggatcac
    63901 taaccgccaa atcgaagctg ctcgtatcgc catgactcgt tacatgaaac gtggtggtaa
    63961 agtttggatt aaaatcttcc cacacaaatc atacactgct aaagctatcg gtgtgcgtat
    64021 gggatctggt aaaggggcac ctgaaggttg ggtagcacca gttaaacgtg gtaaagtgat
    64081 gttcgaaatc gctggtgtat ctgaagagat tgcacgtgaa gcgcttcgac ttgctagcca
    64141 caaattgcca gttaaatgta aattcgtaaa acgtgaagca gaataaggag aaggcatgaa
    64201 acttaatgaa gtaaaagaat ttgttaaaga acttcgtggt ctttctcaag aagaactcgc
    64261 gaagcgcgaa aacgaattga aaaaagaatt gtttgaactt cgtttccaag ctgctactgg
    64321 tcaattggaa caaacagctc gcttgaaaga agttaaaaaa caaatcgctc gtatcaaaac
    64381 agttcaatct gaagcgaaat aatagactag ggaaggagaa atttcaatgg aacgcaataa
    64441 tcgtaaagtt cttgttggac gtgttgtatc tgacaaaatg gacaagacaa tcacagttgt
    64501 agttgaaaca aaacgtaacc acccagtcta tggtaaacgt attaactact ctaaaaaata
    64561 caaagctcat gatgaaaaca atgttgccaa agaaggcgat atcgtacgta tcatggaaac
    64621 tcgcccgctt tcagctacaa aacgtttccg tcttgtagaa gttgttgaag aagcggtcat
    64681 catctaatca aacctgaaag gagaaaactg aaatgattca aacagaaact cgtttgaaag
    64741 tcgcagacaa cagcggtgct cgcgaaatct tgactatcaa agttcttggt ggttcaggac
    64801 gtaaatttgc aaacatcggt gatgttatcg tggcatctgt aaaacaagct actcctggtg
    64861 gtgcggttaa aaaaggtgac gttgttaaag cagttatcgt tcgtactaaa tcaggtgctc
    64921 gtcgtgctga tggttcatac atcaaatttg acgaaaacgc agcagttatc atccgtgaag
    64981 acaaaactcc tcgcggaaca cgtatctttg gcccagttgc acgtgaattg cgtgaaggtg
    65041 gcttcatgaa gatcgtgtca cttgctccag aagtacttta atttttagga acaaactagt
    65101 cccctagctt caagctaggg tgcccttatg ggcgtaagaa aaatcaagga gaaacctaat
    65161 gtttgtaaaa aaaggcgaca aagttcgcgt aatcgctggt aaagataagg gaacagaagc
    65221 tgttgtcctt actgcccttc caaaagtaaa caaagttatc gttgaaggtg ttaacattgt
    65281 taagaaacac caacgtccaa ctaacgagct tcctcaaggt ggtatcatcg agaaagaagc
    65341 agctatccac gtatcaaacg ttcaagtttt ggacaaaaat ggtgtagctg gtcgtgttgg
    65401 ttacaaattt gtagacggta aaaaagttcg ctacaacaaa aaatcaggcg aagtgcttga
    65461 ttaatcacga aggaaaggag aagtataatg gcaaatcgtt taaaagaaaa atatcttaat
    65521 gaagtagttc ctgctttgac agaacaattc aactactcat cagtgatggc tgtgcctaaa
    65581 gtagataaga ttgttttgaa catgggtgtt ggtgaagctg tatcaaacgc taaaagcctt
    65641 gaaaaagctg ctgaagaatt ggcacttatc tcaggtcaaa aaccacttat cactaaagct
    65701 aaaaaatcaa tcgccggctt ccgtcttcgt gaaggtgttg cgatcggtgc aaaagttacc
    65761 cttcgtggtg aacgtatgta cgaattcttg gataaattgg tatcagtttc acttccacgt
    65821 gtacgtgact tccacggtgt tccaacaaaa tcatttgatg gacgcgggaa ctacacactt
    65881 ggtgtgaaag aacaattaat cttcccagaa atcaacttcg atgacgttga caaaactcgt
    65941 ggtcttgaca tcgttatcgt aacaactgct aacactgacg aagagtcacg tgcattgctt
    66001 acaggccttg gaatgccttt tgcaaaataa tataggaggt aaatctaatg gctaaaaaat
    66061 caatggtagc tagagaggct aaacgccaaa aaattgttga ccgttatgct gaaaaacgtg
    66121 ctgcattaaa ggcggcaggg gactacgaag gtttatctaa attacctcgc aacgcctcac
    66181 cgactcgttt acataatcgt tgtagagtta cggggcgccc acattcagtt taccgcaaat
    66241 ttggtctgag tcgtatcgct tttcgcgaac ttgcgcataa aggtcaaatt cctggtgtaa
    66301 caaaagcatc ttggtaattt aagatatcaa gagcgtcaaa actccaagta aaaataggaa
    66361 acttgacgaa gaaactaaag tttctaggaa agtttatctt tttcacacag agtttagccc
    66421 gggttcaatt gggcttgcca atttgaacac gagctacagc tttggcaaaa aagaccaatt
    66481 tgctttggag cattgcttct gcattaaatt gtctattttt gctcgtgctg ttacgctctt
    66541 tgtatcatgt attaactagc aagtgcaact tgcaaactac tagtaagagg agaaaaacaa
    66601 aatggttatg actgacccaa tcgcagactt cctaactcgt attcgtaatg ctaaccaagc
    66661 taaacacgaa gtacttgaag tacctgcatc aaacatcaaa aaagggattg ctgaaatcct
    66721 taaacgcgaa ggttttgtaa aaaacgttga aatcattgaa gatgacaaac aaggcgtcat
    66781 ccgtgtattt cttaaatacg gaccaaatgg tgagaaagtt atcactaact tgaaacgtgt
    66841 ttctaaacca ggacttcgtg tctacaaaaa acgtgaagac cttccaaaag ttcttaacgg
    66901 acttggaatt gccatccttt caacttctga aggtttgctt actgataaag aagcacgcca
    66961 aaagaatgtt ggtggtgagg ttatcgctta cgtttggtaa aatcaagata caaagctcgt
    67021 aaagaacaaa gcaaaattag gaagttggag aagtttgttt acaaacaagc caacttatct
    67081 attttgcaca gttcttagag cgtgttcagt tcagctcttg aactaaataa gtatctgaac
    67141 cccgtgaaaa ctggccgttc tggcctgaca atctaacagg agaaaataaa catgtcacgt
    67201 attggtaata aagttatcgt gttgcctgct ggtgttgaac tcgctaacaa tgacaacgtt
    67261 gtaactgtaa aaggacctaa aggagaactt actcgtgagt tctcaaaaga tattgaaatc
    67321 cgtgtggaag gtactgaaat aactcttcac cgtccaaacg attcaaaaga aatgaaaact
    67381 atccacggaa ctactcgtgc ccttttgaac aacatggttg ttggtgtatc agaaggattc
    67441 aagaaagaac ttgaaatgcg tggggttggt taccgtgcac agcttcaagg atctaaactt
    67501 gttttggctg ttggtaaatc tcatccagac gaagttgaag ctccagaagg aattactttt
    67561 gaacttccaa acccaacaac aatcgttgtt agcggaattt caaaagaagt agttggtcaa
    67621 acagctgctt acgtacgtag ccttcgttca ccagaaccat ataaaggtaa aggtatccgt
    67681 tacgttggtg aattcgttcg ccgtaaagaa ggtaaaacag gtaaataatg ttgagtggtt
    67741 gatcatcaac caccaaccta ttttccaact ttgtgcatag cacacgattt aaaactaaag
    67801 aggtgaaaac tgtgatttca aaaccagata aaaacaaact ccgccaaaaa cgccaccgtc
    67861 gcgttcgcgg aaaactctct ggaactgctg atcgcccacg tttgaacgta ttccgttcta
    67921 atacaggcat ctacgctcaa gtgattgatg acgtagcggg tgtaacgctc gcaagtgctt
    67981 caactcttga taaagaagtt tcaaaaggaa ctaaaactga acaagccgtt gctgtcggta
    68041 aactcgttgc agaacgtgca aacgctaaag gtatttcaga agtggtgttc gaccgcggtg
    68101 gatatctata tcacggacgt gtgaaagctt tggctgatgc agctcgtgaa aacggattga
    68161 aattctaata ggaggacact agaaaatggc atttaaagac aatgcagttg aattagaaga
    68221 acgcgtagtt gctgtcaacc gtgttacaaa agttgttaaa ggtggacgtc gtcttcgttt
    68281 cgcagctctt gttgttgttg gtgaccacaa tggtcgcgta ggatttggta ctggtaaagc
    68341 tcaagaagtt ccagaagcaa tccgtaaagc agtagatgat gctaagaaaa acttgatcga
    68401 agttcctatg gttggaacaa caatcccaca cgaagttctt tcagaattcg gtggagctaa
    68461 agtattgttg aaacctgctg tagaaggttc tggagttgcc gctggtggtg cagttcgtgc
    68521 cgttgtggaa ttggcaggtg tggcagatat tacatctaaa tcacttggtt ctaacactcc
    68581 aatcaacatt gttcgtgcaa ctgttgaagg tttgaaacaa ttgaaacgcg ctgaagaaat
    68641 tgctgccctt cgtggtattt cagtttctga tttggcataa gaaaggggat aaaatggctc
    68701 aaattaaaat tactttgact aagtctccaa tcggacgcat tccatcacaa cgtaaaactg
    68761 ttgtagcact tggacttggc aaattgaaca gctctgttat taaagaagat aacgctgcta
    68821 tccgtggtat gattacagca gtatctcact tagtaacagt tgaagaagta aactaatgaa
    68881 gttttagggg atgtgcactg taccatcccc taaaactaga tatagtcatc tatgatgaca
    68941 tcgtataggc gagttgatgg gggagacaac cttttctccc ttatcggcgc tagcatttta
    69001 caaaagagga gaaaataaaa atgaaacttc atgaattgaa acctgcagaa ggttctcgta
    69061 aagtacgtaa ccgcgttggt cgtggtactt catcaggtaa cggtaaaaca tctggtcgtg
    69121 gtcaaaaagg tcaaaaagct cgtagcggtg gcggagttcg ccttggtttt gaaggtggac
    69181 aaactccatt gttccgtcgt cttccaaaac gtggattcac taacatcaac gctaaagaat
    69241 acgcaattgt gaaccttgac caattgaacg tctttgaaga tggtgctgaa gtaactccag
    69301 ttgttcttat cgaagcagga attgttaaag ctgaaaagtc aggtattaaa attcttggta
    69361 acggtgagtt gactaagaaa ttgactgtga aagcagctaa attctctaaa tcagctgaag
    69421 aagctatcac tgctaaaggt ggttcagtag aagtcatcta agagaggtga cctatgtttt
    69481 ttaaattatt aagagaagct cttaaagtca agcaggttcg atcaaaaatt ttatttacaa
    69541 tttttatcgt tttggtcttt cgtatcggaa ctagcattac agttcctggt gtgaatgcca
    69601 atagcttgaa tgctttaagt ggattatcct tcttaaacat gttgagcttg gtgtcgggga
    69661 atgccctaaa aaacttttcg atttttgccc taggagttag tccctatatc accgcttcta
    69721 ttgttgtcca actcttgcaa atggatattt tacccaagtt tgtagagtgg ggtaaacaag
    69781 gggaagtagg tcgaagaaaa ttgaatcaag ctactcgtta tattgctcta gttctcgctt
    69841 ttgtgcaatc tatcgggatt acagctggtt ttaatacctt ggctggagct caattgatta
    69901 aaactgcttt aactccacaa gtttttctga cgattggtat catcttaaca gctggtagta
    69961 tgattgtcac ttggttgggt gagcaaatta cagataaggg atacggaaac ggtgtttcca
    70021 tgattatctt tgccgggatt gtttcctcaa ttccagagat gattcagggc atctatgtgg
    70081 actactttgt gaacgtccca agtagccgta tcacttcatc tatcattttc gtaatcattt
    70141 tgattattac tgtattgttg attatttact ttacaactta tgttcaacaa gcagaataca
    70201 aaattccaat ccaatatact aaggttgcac aaggtgctcc atctagctct taccttccgt
    70261 taaaggtaaa ccctgctgga gttatccctg ttatctttgc cagttcgatt actgcagcgc
    70321 ctgcggctat tcttcagttt ttgagtgcca caggtcatga ttgggcttgg gtaagggtag
    70381 cacaagagat gttggcaact acttctccaa ctggtattgc catgtatgct ttgttgatta
    70441 ttctctttac attcttctat acgtttgtac agattaatcc tgaaaaagca gcagagagcc
    70501 tacaaaagag tggtgcctat atccatggag ttcgtcctgg taaaggtaca gaagaatata
    70561 tgtctaaact tcttcgtcgt cttgcaactg ttggttccct cttccttggt gtgatttcca
    70621 ttttaccgat tgcagctaaa gatgtatttg gtctttctga tgttgttgcc tttggtggaa
    70681 caagtctctt gatcattatc tctacaggta tcgaaggaat caagcaattg gaaggttacc
    70741 tattgaaacg taagtatgtt ggtttcatgg acagaacaga ataaaagtat ttactgaatc
    70801 agtaaatgct gagggagtgg aggtttaaac tctgacattt gtaagagttg gatctcccct
    70861 cttctatttt gtttttaaat aggggtgaaa agactttttg cttctattta aaaataaaat
    70921 aaggagatca aatcatgaat cttttgatta tgggcttacc tggtgcaggt aagggaactc
    70981 aagcagcaaa aatcgtagaa caattccatg ttgcacatat ctcaacaggt gatatgttcc
    71041 gcgctgcaat ggcaaatcaa actgaaatgg gtgttcttgc taagtcatat attgacaagg
    71101 gtgaattggt tcctgacgaa gttacaaatg gaatcgtaaa agaacgcctt tcacaagatg
    71161 atattaaaga aacaggattc ttattggatg gttacccacg tacaattgaa caagctcatg
    71221 ccttggacaa aacattggct gaacttggca ttgaactaga aggtgttatc aatattgaag
    71281 tgaactctga cagcctcttg gaacgtttga gtggccgtat catccaccgc gtaactggag
    71341 aaactttcca caaggtcttt aacccaccag ttgactataa agaagaagat tactaccaac
    71401 gtgaagatga taagcctgag acagtaaaac gtcgtttgga tgttaatatt gctcaaggag
    71461 aaccaatcat tgctcactac cgtgccaaag gtttggttca tgacatcgaa ggtaatcaag
    71521 atatcaatga tgtcttctca gatattgaaa aagtattgac aaatttgaaa taaagcgttt
    71581 ttcatacttg caaaaattcg ctataaatgt tatactgaga tagtctgact tataattgtt
    71641 gtctctgtgt ctagaggcat cgaatcgaaa tttatggagg tgcttttgcg tggcaaaaga
    71701 cgatgtgatt gaagttgaag gcaaagtagt tgatacaatg ccgaatgcaa tgtttacggt
    71761 tgaacttgaa aatggacatc agattttagc aacagtttct ggtaaaattc gtaaaaacta
    71821 tattcgtatt ttagcgggag atcgtgttac tgtcgaaatg agtccatatg acttgacacg
    71881 tggacgtatc acttaccgct ttaaataatc gaaaaacttg gagggataag aaatgaaagt
    71941 aagaccatcg gtcaaaccaa tttgcgaata ctgtaaagtt attcgtcgta atggtcgtgt
    72001 tatggtaatt tgcccagcaa atccaaaaca caaacaacgt caaggataag atagaaagga
    72061 gaaaacatgg ctcgtattgc tggagttgat attccaaatg acaaacgcgt agtaatctca
    72121 ttgacttatg tttatggtat cggacttgca acatctaaga aaattttggc tgctgctgga
    72181 atctcagaag atgttcgtgt acgtgatctt acatcagatc aagaagatgc tatccgtcgt
    72241 gaagtggatg caatcaaagt tgaaggtgac cttcgtcgtg aagtaaactt gaacatcaaa
    72301 cgtttgatgg aaatcggttc ataccgtggt atccgtcacc gtcgtggact tcctgtccgt
    72361 ggacaaaata ctaaaaacaa cgctcgcact cgtaaaggta aagctgttgc gattgctggt
    72421 aagaaaaaat aatataggag gtaaaagtct tggctaaacc aacacgtaaa cgtcgtgtga
    72481 aaaagaatat cgaatctggt attgctcata ttcacgctac atttaataac actattgtta
    72541 tgattactga tgtgcatggt aatgcaattg cttggtcatc agctggtgct cttggtttca
    72601 aaggttctcg taaatctaca ccattcgctg ctcaaatggc ttctgaagct gctgctaaat
    72661 ctgcacaaga acacggtctt aaatcagttg aagttactgt aaaaggtcca ggttctggtc
    72721 gtgagtcagc tattcgtgcg cttgctgccg ctggtcttga agtaacagca attcgtgatg
    72781 tgactccagt gccacacaat ggtgctcgtc ctccaaaacg tcgccgtgta taatcatcgc
    72841 attacactgc ttttcgttta agagggagta actaaatgat cgagtttgaa aaaccaaata
    72901 taacaaaaat tgatgaaaat aaagattatg gcaagtttgt aatcgaacca cttgaacgtg
    72961 gctacggtac aactcttggt aactctcttc gtcgtgtact tctagcttct ctaccaggag
    73021 cagctgtgac atctatcaac attgatggtg tgttacatga gtttgacaca gttccaggtg
    73081 ttcgtgaaga cgtgatgcaa atcattctga acattaaagg aattgcagtg aaatcgtacg
    73141 ttgaagacga aaaaatcatc gaactggatg ttgaaggtcc tgctgaagta acagctggtg
    73201 acattttgac agatagcgat attgaaattg taaatccaga tcattatctc tttacaatcg
    73261 gtgaaggttc ttctctaaaa gcgactatga ctgttaacag tggtcgtgga tatgtacctg
    73321 ctgatgaaaa taaaaaggat aatgcaccag ttggaacact tgctgtagat tctatttata
    73381 caccagttac aaaagtcaac tatcaagtgg aacctgctcg tgtaggtagc aatgatggtt
    73441 tcgacaaatt aacccttgaa atcttgacaa atggaacaat tattccagaa gatgctttag
    73501 ggctttcagc acgtattttg acagaacatc ttgatttgtt tacaaatctt actgagattg
    73561 ctaagtcaac tgaagtgatg aaagaagctg atactgaatc tgacgaccgt attttagatc
    73621 gtacgattga ggaactggac ttgtctgtgc gttcatacaa ctgtttaaaa cgtgccggta
    73681 tcaatactgt gcatgatttg acagaaaaat ctgaagcaga gatgatgaaa gtacgaaatc
    73741 ttggacgcaa gagtttggaa gaagtgaaac tcaaactcat tgatttgggt cttggattaa
    73801 aagataaata aaggaggaat acatggctta ccgtaaacta ggacgcacta gctcacaacg
    73861 taaagcaatg cttcgcgatt tgacaactga ccttttgatc aacgaatcaa tcgtgacaac
    73921 tgaagctcgt gctaaagaaa tccgtaaaac tgttgaaaaa atgattactc taggtaaacg
    73981 tggtgatttg catgcacgtc gtcaagcagc tgctttcgta cgtaatgaaa tcgcatctga
    74041 aaactatgat gaagcaactg ataagtacac ttctactaca gcacttcaaa aattgttctc
    74101 agaaatcgca cctcgttatg ctgaacgtaa cggtggatac actcgtatcc ttaaaactga
    74161 accacgtcgt ggtgatgcag cgccaatggc gatcatcgaa ttagtataaa atcatcaatt
    74221 ttgttgagtg ttatgatgat ggagtcttgt gctcttagtc tagctctggt ctaccgctag
    74281 gatttcggtc ctagcgggaa cactcatcat aagttgggat agtagacgct tgtttacgaa
    74341 attgtttttt tcttaagaac aacttcgtaa gcaggcgttt ttgagtattt tcgttagaat
    74401 tatgctatac tatttgaaaa gaatcctgtt taatgttaag gtttcttatt ttaagaagaa
    74461 ttggagttta cttatgaaag ccattataac tgttgttggt aaagataaat ctggaattgt
    74521 tgcaggtgtt tctggtaaaa ttgcagaatt aggattgaat attgacgata tctctcaaac
    74581 tgtcttggat gaatatttta cgatgatggc tgttgtatct agtgatgaaa agcaagattt
    74641 tacctatctt cgtaatgaat ttgaagcttt tgggcaaact ttgaatgtaa aaatcaatat
    74701 tcagagtgca gcgattttcg aagctatgta taatatctag gaggtcatca tggatattag
    74761 acaagttact gaaaccatcg ccatgattga ggagcaaaac ttcgatatta gaaccattac
    74821 catggggatt tctcttttgg actgtatcga tccagatatc aatcgtgctg cggagaaaat
    74881 ctatcaaaaa attacgacaa aggcggctaa tttagtagct gttggtgatg aaattgcggc
    74941 tgagttggga attcctatcg ttaataagcg tgtatcggtg acacctattt ctctgattgg
    75001 ggcagcgaca gatgcgacgg actacgtggt tctggcaaaa gcgcttgata aggctgcgaa
    75061 agagattggt gtggacttta ttggtggttt ttctgcctta gtacaaaaag gttatcaaaa
    75121 gggagatgag attctcatca attccattcc tcgcgctttg gctgagacgg ataaggtctg
    75181 ctcgtcagtc aatatcggct caaccaagtc tggtattaat atgacggctg tggcagatat
    75241 gggacgaatt atcaaggaaa cagcaaatct ttcagatatg ggagtggcca agttggttgt
    75301 attcgctaat gctgttgagg acaatccatt tatggcgggt gcctttcatg gtgttgggga
    75361 agcagatgtt atcatcaatg tcggagtttc tggtcctggt gtggtgaaac gtgctttgga
    75421 aaaagttcgt ggacagagct ttgatgtagt agccgaaaca gttaagaaaa ctgcctttaa
    75481 aatcactcgt atcggtcaat tggttggtca aatggccagt gagagactgg gtgtggagtt
    75541 tggtattgtg gacttgagtt tggcaccaac ccctgcggtt ggagactctg tggcacgtgt
    75601 ccttgaggaa atggggctag aaacagttgg cacgcatgga acgacggctg ccttggccct
    75661 cttgaacgac caagttaaaa agggtggagt gatggcctgc aaccaagtcg gtggtttatc
    75721 tggcgccttt atccctgttt ctgaggatga aggaatgatt gctgcagtgc aaaatggctc
    75781 tcttaattta gaaaaactag aagctatgac ggctatctgt tctgttggat tggatatgat
    75841 tgccatccca gaagatacgc ctgctgaaac cattgcggct atgattgcgg atgaagcagc
    75901 aatcggtgtt atcaacatga aaacaacagc tgttcgtatc attcccaaag gaaaagaagg
    75961 cgatatgatt gagtttggtg gtctattagg aactgcaccc gttatgaagg ttaatggggc
    76021 ttcgtctgtc gacttcatct ctcgcggtgg acaaatccca gcaccaattc atagttttaa
    76081 aaattaagaa aataggagaa attttaagtt ctatttaaga ttagacgtgt atactataat
    76141 cattaaataa agacctccta atattatttg aaacagataa cactgaatta gtttgaattt
    76201 gattttcatc taatatcttt atttaatgaa ctcctaaact ttttcataat aatctccttc
    76261 aaaagtcgcc tgtatgggtg gcttttattt tatcattcat gatataatag aagcaaacgg
    76321 aggacggaaa atggtaaaag tacgattgta tttggtacgt catggcaaga ccatgtttaa
    76381 cacgattggt cgcgcgcaag gttggagcga tactccctta actgctgaag gtgaacgagg
    76441 gattcaagag ttaggaatcg gtttgcgaga atctgatcta cagtttgagc gcgcttattc
    76501 gagtgattct ggtcgtacca ttcagaccat gggaattata cttgaagaac ttggcttgca
    76561 ggggaaaatc ccttatcgca tggacaagcg tatcagagaa tggtgtttcg gtagttttga
    76621 tggagcctat gatggcgatc ttttcatggg cattattcct cgtatcttta atgtggacca
    76681 cgttcaccaa ttgtcttatg ctgaactggc tgagggcttg gtagaggtcg atacagctgg
    76741 ttgggctgaa ggctgggaaa aactcagtgg ccgaatcaag gaaggctttg aaataattgc
    76801 aaaagaaatg gaagatcaag gtggaggtaa cgcccttgtt gtcagccatg gaatgactat
    76861 tggaaccatt gtttatctga ttaatggcat gcatccgcat ggtctagata atggtagcgt
    76921 gacgattctt gaatatgagg acggtcagtt tagggttgaa gttgtcggtg accgtagtta
    76981 ccgagagcta ggacgtgaga agatggaaga aggctctatt taatcagtct agacttgctt
    77041 gccatgagct agggatttga taaggatatc aagataagaa aaaacagccg agggtactcc
    77101 tttcggctgt ttttgatgtg gaaaactaaa gtgtaatgct attgctttta gagattttca
    77161 taaacaagag caaggaacct actgttagaa cagtcaggat agttgacaag gctgcggcta
    77221 caccgtaatt tcctctgaga acctctgtat aaatagctac agtcattgtt cttgttttga
    77281 cattgtagag gaggatagaa gtagagagtt ttgaaatcat tgtgacccaa gataagatgg
    77341 ctccagaaat gataccagat agcatcattg gagttgtaat cttagcaaag gtattgagac
    77401 gactacttcc taagctttca gcagcttctt caatacttgg tgctatttgt tgtaagctag
    77461 caacagatga gcgaatagta taaggtaatc ttctgacaga tagagacata atcaagatga
    77521 aagcagtccc tgtaatcata agaaatccac ttccaaatag accagtattg aaggaagaaa
    77581 tgaaggcaat ccctagaacg gttcctggta caatataagg taccatactg aggctgtcaa
    77641 ttaagtttgt aaacaaattc cgttttctaa cggctaggta ggagataaat gtcgcaaata
    77701 gaacaactag aactaaggca atcaaaggga tacgaatggt attgaaaata gcagatccca
    77761 tacgattgaa agctaccttg taactgtttg gagaataacc ttcaacaaat accatacctg
    77821 atgtttttag gaaagaggta taaattaagt agatttgagg taaaacagag ataaagataa
    77881 ttccgtagac tgttgcataa atggcagcca tttttccttt tgtagttttt ttaggctcaa
    77941 ttggatggag cagattcatg ctgaaactgt agcggtttgc aatgtgtttt tggataagga
    78001 aaattgccaa ggcaatgata atcgccataa ttgcaaaagc agaatttcct ccaacctcgc
    78061 taataaattg ggtataaatc aggacaggga aagtccgata tccttcgcca atcaacatag
    78121 gcgttccaaa gtctgagaat gctctcataa atacaagcaa ggagctgcta gtaaggttgg
    78181 aactaggaga ggtaaaacaa ccgttacgat acgcttaaat ccgaaggacc ccatgctttc
    78241 agctgcttca agtagagaat tgtcaatact gttcattgtt ccagcaacat atagaaatac
    78301 cagtgggaat agttgcagtg taaagacaag tacaattcct ttgaatccat aaatatcgat
    78361 agctggaaga taaagggcat ttgtcaaaaa tttagtgatg acctcatttc gtcctagcaa
    78421 gagaacccag gagtaggctc ctacgaaagg agctgacatg gaagcaatga taatcaatat
    78481 ttgtagaaat ttctccccct tgaagtcata catagagaag agataagcta atagggttcc
    78541 tacaactaag gaagtgacag tagcggtaat ggaaaccttg aaactgttga ctagtgtctc
    78601 agagtagtag actttactaa agaaagtgac aaaattagct agtgagaatt gtccttcatg
    78661 tataagtgct tacttgagca cggtaacgat aggataaacg agaaagacaa gataggtaag
    78721 aaagatgaag aaagaggagg ctgtccaaat atttagtttt ttacgttcca tggttgactc
    78781 cttttatcag gttttgggaa ccatctgcag aaaagatgtt taatttttgc gtattgattc
    78841 gtagacgaat acgattgcct ttttgtagat cttcttcaaa agttgattct tcactaactt
    78901 gaatttttga ggcaaaacct gtctcaatga aatactccgt atttagtcca agatagacgc
    78961 tatcgctaat agttccttca atatctccag attcatcttt gataaactct tcgggacgaa
    79021 tgcttacatg aatagcttgc tcctcaacct gatcaagagc tagcattcga agggcatagc
    79081 catctgaaaa gacgatataa gcgccgtcgc tccgtttttc aagattggca gggataatat
    79141 ttgtgcgtcc gataaaggtt gccacaaact cattagctgg tttatgatag agttcttttg
    79201 gtcggccgat ttgttggatc accccatctt tcataacagc aatttggtct gaaatagcca
    79261 tggcttcttc ttggtcgtgg gttacataaa cagttgtaat tcccacttcg tgttggattt
    79321 ctcggatggc ttgacgcata tccaagcgaa gtttggcctc cagattacta agtggctcgt
    79381 ccatgaggag aacacttaga ttaaccgcta aggcgcatgc caaggtgaca cgttgttgtt
    79441 gtccaccact gagtttatcg ggctttcgat ccgcatattg agcaatttgc atgagttcaa
    79501 gatacttgtt ggtctgttga atcaattctt cttttggaac cttcttttgc ataagaccaa
    79561 aagcaacgtt gtctcggaca gtcaaatgtg ggaaaatagc gtagttttgg aaaaccatcc
    79621 cgatattgcg tttgctgggt tccatattat tgatttttgt atcatcgaag taaaattctc
    79681 catctttgat actgttgaaa cctgcaatca tacgaagaag ggtcgttttc ccacatcctg
    79741 aagctccaag aagggtaaag agacttcctt ttggaattgt aatgttcaaa ttctcaataa
    79801 cagagacatc gtggtagatt ttttttgcgt taataatttc gatctcactc atagtgaacc
    79861 tcttttactg tttagattgg atatctgtaa agacttcgtt gtatttctta acgatatctg
    79921 atttattctt gatgacataa tcataatctt cagtgagtgt tttgattttg tcaattggtt
    79981 tcatgttttc gcttgtttta gcatttttac gaacaggacg gttagtagtg gttgtaccaa
    80041 gtgtatcttg tacttcttga gagataataa aatcgataaa tttcttggca ttttccatat
    80101 ttttagattt tttaacgata gcagcactag caggtaggaa gacggttcct tcttttggat
    80161 agactacctt aatgttagct ccgtcattta agagtttaac tgctggatct tcataagaga
    80221 gaccaacagt catttctcca tcagcgactg ctttatagac accagatgaa cttaaaccga
    80281 ttttatagta tattgaaact agaatagtac acatctactt ctaaaacatt gttagaaatc
    80341 gatttgactg tcctgattaa tttgtcctgt tcttatttca ttttactata ccatcaataa
    80401 gtgtgaaaag atcttttaca taagaccaag ccttatcatc tttgtaacca ccttgagctt
    80461 gtagcatatt tgttaattga gcaaaggcgc tagaagagtt tgctgggtca gcagttgcga
    80521 tttttccttt tagttcaggt ttgagaaggt cgctatatcc ttcgatgttc atgcctttag
    80581 ttaaatcagg gtggacgatt aaaacactac catctagtgt ataaggagta gagaagccag
    80641 ttgtgttttg atattctttg ataacattat cattttcttt tgaaatatag ttttcaaaga
    80701 gttctccgtg ggtagcatat tgtgtataag aaccaccaaa gataacatca gctacaggaa
    80761 cttctttttc tgactctagt tttttgaaaa gttctccagt accagcttga atcagttcta
    80821 ttttgatacc atatttttct tcaaaggcag gaatagttgc tccaattaag ccttctgagt
    80881 ttggtcaata aacgactagc gaaccaccgt ctcctttatc agatgaactg tcatcggcag
    80941 attcattaga agaacaagca gcataataca tccatttctt tttcatgatg gatacctccg
    81001 ttgtgttatt taagtttatt ttaaaacaat gtaagcgttt ttaaaaccta caattctatt
    81061 ctatagtgta ttgaatctat aacagtacac tttgactgct aaaatatttc tataaattaa
    81121 tttgactttc ctgatagaga tgttcacatc ttatttcaat tcactatatt agagtaaaat
    81181 tctctacaaa aagaagaata gcctatttta ctattcttcc gagtgatttc aatttctttg
    81241 gggaaatatg gagatacttt ttaaatactt tggcaaaata tttatagtct gaaaatccaa
    81301 cttggtcaga gatagcgctt aaaggggagt tgggagattc agccatctta tctatagctt
    81361 gtttcaggcg atattgtaag atatattcat ttagagtcat ggggaagtct tctttgataa
    81421 ccttatatag atgcttgtta tctgcaaata gctagagcgt ttcaaggaaa tgaactagaa
    81481 ataacaatta atatggtggt tcagaaatac cttttgataa tcaataagat cttcaggatg
    81541 aagtgcgttg actccatcca tttcatattt ccgatttaat aaacgatatt tgttttcacc
    81601 aaattgatga aaagggagta gttgaacttg gtcgatattt aatgagttaa atagagtagc
    81661 gaatttttct gcatcctcta aactattgtt aaaattagga ataactggga ttcttaaaac
    81721 gatagtttta ttttgagaaa aagcataatg aatgttttta ataatcattt gattaaaaac
    81781 cccagtcact tttttatgtt ttatagaatt ataatgtttt aggtctgtgt agataaaatc
    81841 cacatattga attaaatcaa taaatttttc atgatcaaca aaggcagtag tttcaatggc
    81901 agtgtgtatg tgatgttctt tagctgattt taagatggct ttagcaaatt caaactgagc
    81961 aaatatttca cctcctgata aagttaaacc tccaccggat tcttcgtaaa attctttgtc
    82021 ttttaatacc tctgtaataa tttcttctac agtcttttct tcaccgacta aggtgaattt
    82081 ctctcgttga gcatctttca ttttttcagg tttcattctt tgagattcag gattagaaca
    82141 ccatggacag cgcagaggac atccttttaa aaaaacagtt gtacgaatac ccggaccgtc
    82201 atgaattgaa aagtgttgaa tattaaaaat aattccttta gatatttcca taagagttcc
    82261 tcctcttcat aagtctatcc tatcacaaaa acgaaagaaa aacaattacg aacgaaagtt
    82321 taatttgttg ttttttgctt tttattttgg tagaataaaa cggaggtgta aaatgaaaag
    82381 attggaacaa attattaaat tagtatcaga acatgaaaag atcgacgtta atacattatc
    82441 ggaaaaatta aatgtatcga aagtaacgat tagaaaagat ttagataaat tagagtcaaa
    82501 aggtttatta cacagagagc atggatatgc tgtattaaat agtggagatg acttaaatgt
    82561 acgtttgtca attaactatg aaattaagag aaaaattgtt caggaagcag taaaattggt
    82621 gtcagataat gaaacaataa tgatagaatc tggatcgacc tgtgctttac ttgctgagga
    82681 aatttgcaag caaaaaagaa atgttacgat tgtaacaaat tcatttttta tagcaaattt
    82741 tgtgagagct tatgattcat gtcgtattat tgttcttggt ggagagtttc agaaggattc
    82801 acaggttact gtgggacctt tattaaaaga aatgatacag acttttcatg tgcatcaagc
    82861 ttttgttggg acagatggtt acgataaaga gatgggcttt acaggaaaag atttaatgcg
    82921 cagtgaggta gttcaatata tttcagcagc gtcggataaa gtcattgtac taactgactc
    82981 aagtaaattt gataaaagag gtacagtaag aagatttgct ttaagtcaag tctatgaagt
    83041 aataacagac gaaaaacttt ctaaacaaaa tatagctaca ttagaaaatg ctgggataat
    83101 ggttaaggta gtttcgtaag aggttaagtg tatgaatcaa gataggaata aactgctttc
    83161 taaaattgct tatctgtatt atattgaaaa cttaaatcag tcacaaatag cagcaaaatt
    83221 aggaatttat agaacctcta ttagtagaat gttaacagaa gcaaggaatg taggaattgt
    83281 taaaattgaa atagagaatt ttgataccaa tatgtttaag ttggaaaatt atgtaaaaga
    83341 aaaatacagt ttggaaagtt tagaaattat tccaaatgaa tttgatgata ctccaacaat
    83401 tttatctgaa agaatttctc aagttgcagc aggcgtcctt aggaatctaa ttgatgataa
    83461 tatgaaaatt ggcttttctt gggggaaaag tttaagtaat ttagtagatt taattcacag
    83521 taaaagtgtc cgaaatgttc acttctatcc tctagcaggt ggtcctagtc acatacacgc
    83581 taaataccat gtgaatacac tgatttatga aatgtctaga aaatttcatg gagagtgtac
    83641 atttatgaat gcaacgattg tgcaagaaaa taaattgtta gcagatggta ttttgcaatc
    83701 aagatatttt gaaaatttga aaaatagttg gaaagattta gatatagctg tagtcggaat
    83761 tggtgatttt agcaataaag ggaaacatca atggttagac atgcttacag aggatgactt
    83821 taaagaattg accaaagtta aaactgtagg agaaatttgt tgtcgatttt ttgattcaaa
    83881 aggtaaagaa gtctatgaaa acttacagga aagaacgata gccatctctt tggaagattt
    83941 aaaaaatatt cctcaaagtt tagctgttgc ttacggtgat acgaaagtat cttcgattct
    84001 ttctgtcttg cgtgctaatt tagtaaatca tttgattaca gacaaaaata caattttaaa
    84061 agttttggaa gaagatgggg atttgacttt tagagagatt ctaggtgagt gaaaatgata
    84121 gactgattca gtttatcgtt tttcttttta gttgattgca catttgtgct tatataaaca
    84181 aaaatagttt atctgttgtt tttggattga caactttatt atgtagttgt attctatagt
    84241 tacaaaagaa aattttaaaa tttcaaatga aaaaagcttt ttacatagtg aaatgaggag
    84301 gaatttatgg aaattattgt tccagatcaa attatcatgg gtttaatttt atatgctggt
    84361 gatgcgaaac aacatattta taaagcgtta gattacataa aaaatggtac atgtgaacga
    84421 tgtgaagaag aaatccagtt agctgatgca gccttattag aagctcataa tctacaaaca
    84481 aaattcttgg cacaggaagc gtctggtaca aagacagaaa ttacagctct ctttgttcat
    84541 tcacaagatc atctcatgac tagtatgacg gagattaatt taatcaaaga aattattagt
    84601 ttgagaaaag aacttcataa aaaataatac tagagtatta tcattgttat taacatagag
    84661 gaggaaaaca taatggtgaa gattggtttg ttttgtgcag caggtttttc tactggtatg
    84721 cttgtaaata atatgaaaat tgcagcgcaa gctagtggag ttgaggcaga aatagaggcg
    84781 ttttctcagt ctaaattagc ggattatgcg ccaaatatag atgttgcact attgggtcca
    84841 caagttgctt atacattaga taaatcaaaa gaaatttgtg ataagtgtga tgttccgata
    84901 gctgttattc cgatgatgga ctatggtatg ttagatggga aaaaagtatt agatttggcc
    84961 ctatctttga ttagtgggta agaaaaggag atttattatg gcaaagatgg atgttcagaa
    85021 aatcattgca ccgatgatga agtttgtgaa tatgcgtggc attatagctc taaaagatgg
    85081 gatgttagca attttgccat tgacagtagt tggtagtttg ttcttgatta tgggacaatt
    85141 gccgttcgaa ggattaaata agagcattgc tagtgttttt ggagctaatt ggacagagcc
    85201 gtttatgcaa gtatattcag gaacttttgc tattatgggt ctaatttctt gtttttcaat
    85261 tgcctattct tatgctaaga atagcggagt agaggcttta ccagctggag ttctatctgt
    85321 atctgcattc tttattttgc taagatcatc ttatatccct aaacaaggtg aggcgattgg
    85381 ggacgctatt agtaaagttt ggtttggagg ccaaggaatt atcggtgcta tcattatagg
    85441 tttggtagta ggaagtattt ataccttctt tataaagaga aaaattgtta ttaagatgcc
    85501 agaacaagtt ccacaagcta ttgccaaaca gtttgaagca atgattccag catttgtaat
    85561 tttcttatct tctatgattg tatatatttt agcgaagtca ttgactaatg gcggaacatt
    85621 catagaaatg atttattctg ctattcaagt tccgttgcaa ggtttaactg gatctttgta
    85681 tggtgctatt ggaattgcat tctttatatc atttttgtgg tggtttggtg ttcatgggca
    85741 atcggtagta aatggagtag tgacagctct gcttttatct aatcttgatg ctaataaagc
    85801 tatgttagcc tctggtaatc tatcattaga aaatggtgca catattgtta ctcaacaatt
    85861 tttagattca tttttaattc tatcaggttc agggattacg tttggtcttg tagttgccat
    85921 gctttttgca gcaaaatcaa aacaatacca agccttagga aaagttgcag cttttccagc
    85981 aatatttaac gtaaatgagc cagttgtatt tggatttccg attgtcatga atccagttat
    86041 gtttgtacct ttcattcttg ttcctgtact tgcagctgtg atagtatatg gagctattgc
    86101 aacaggtttc atgcagccat tctcaggggt aacattgcct tggagtacac cagctattct
    86161 atcaggattt ttggtgggtg gatggcaagg tgttgtgact cagttattag tattggtgat
    86221 atctacagtg gtttactttc cattctttaa gatacaagat cgtttagctt accaaaatga
    86281 aatcaaacaa tcttagaggt atttgtgtgt tactgttaaa ctcacacatt tgtgctaaaa
    86341 attagagagt taaaattttt ctagttaaaa gcttgaaaat ttctataaaa atcggtatta
    86401 tattttcgaa agaaataaaa atattttcga aagaaaggtg cttacgatgg taaatacaga
    86461 agtagcaaga acaacaatca agacagaata ttttggcagc cttactgaaa ggatgaacaa
    86521 atatcgagaa gatgttttaa ataaaaaacc ttatattgat gctgagagag cagttctagc
    86581 aacacgcgcc tatgaacgat acaaggaaca acctaatgtc ctaaaacgtg catatatgct
    86641 gaaagaaatt ttggaaaata tgtctatcta tattgaagaa gaatctatga ttgcgggaaa
    86701 tcaagcttct tccaataaag atgctcctat ttttccggaa tatacgctag aatttgttct
    86761 caatgagttg gatctttttg aaaagcgtga tggagatgtt ttctatatta cagaagaaac
    86821 aaaagaacaa cttagaagta ttgctccgtt ttgggaaaat aataatttac gtgctagagc
    86881 tggtgcctta ttacctgaag aagtgtctgt ttatatggaa acaggattct tcggtatgga
    86941 aggtaagatg aattctggag atgctcactt agcagttaac tatcagaaac ttttgcaatt
    87001 tggtttaaga ggttttgaag agcgggctcg taaagcaaaa gtagctctag atttaacaga
    87061 tccagcaagt attgataaat atcattttta cgactctata tttatcgtaa tcgatgctat
    87121 taaagtatat gcaaagcgct ttgttgctct tgctaaaagt ttagccgaaa atgcaaatcc
    87181 taaacgtaag aaagaattac ttgagattgc agatatttgc tctagagtcc catatgaacc
    87241 ggcaactact tttgcagaag ctattcaatc agtttggttt attcaatgta ttttacaaat
    87301 tgaatctaat ggccactctc tttcatatgg ccgttttgat caatatatgt atccatatat
    87361 gaaggctgat ttagaaagtg gtaaagaaac agaagatagc attgttgaac gtctgacaaa
    87421 tctttggatt aagacaatta caatcaataa ggttcgcagt caatcacata cattttcttc
    87481 agcaggaagt cctttatatc aaaatgttac aattggtgga cagactcgag ataagaagga
    87541 tgctgttaac ccattatctt atttggtatt aaaatcagtt gcacaaaccc atctaccgca
    87601 acctaatcta actgtacgtt accatgcagg tttagatgct cgtttcatga atgagtgtat
    87661 tgaagtgatg aaacttggtt ttggtatgcc tgcatttaat aatgatgaga ttattattcc
    87721 ttcttttatt gcaaaaggag tattggaaga tgatgcttat gattacagtg ccattggatg
    87781 tgttgaaacg gcagttccag ggaaatgggg ctatcgttgc acaggtatga gttatatgaa
    87841 cttccctaag gttctactta tcacgatgaa tgatggaatt gatccggctt cgggtaaacg
    87901 gtttgcacca agctttggtc attttaagga tatgaagaac ttttctgaat tagaaaatgc
    87961 ttgggataaa acactaagat atttgacacg aatgagtgtt attgttgaaa attctattga
    88021 tttatcattg gaacgagaag ttcctgatat tctatgttca gcattgactg atgattgtat
    88081 tggtcgtgga aaacacctta aagaaggtgg agcagtatat gattatatat caggattgca
    88141 agttggaatt gcaaatttgt cggattcatt agctgcaatt aaaaaattgg tgtttgagga
    88201 agaacgtata agcccaagtc agctttggca tgcactggaa acagattatg ccggagaaga
    88261 aggtaaggtc attcaagaaa tgttgattca tgatgcacct aagtatggta atgatgatga
    88321 ttatgctgac aaattggtta ctgctgctta tgacatttat gttgatgaaa ttgctaaata
    88381 tcctaataca cgttatggaa gagggcctat tggaggaatt cgttattcag gaacatcttc
    88441 tatatcagcc aacgtagggc agggacgtgg aacattagca actccagatg gacgcaacgc
    88501 gggtacaccg ttagcagagg gttgttcacc atcacataat atggatcaac acggccctac
    88561 atctgtttta aaatctgttt caaaattacc aacagatgaa atcgtaggtg gggttctctt
    88621 aaatcagaaa gtaaatcctc aaacgttagc caaagaagaa gataaattaa aactaattgc
    88681 tttgttacga acattcttta atcgtttaca tgggtaccat attcaataca atgttgtttc
    88741 cagagagacg ttgattgacg ctcagaaaca tcctgaaaaa cacagagact taattgttcg
    88801 tgttgcagga tactctgcat tcttcaatgt tctttctaag gcaacccaag atgacattat
    88861 aggacgtact gagcatactt tgtaaaataa agaggttctt tttatggaat ttatgcttga
    88921 cacattaaat ttagatgaga ttaaaaagtg gtctgaaatt ttgccgctag ctggggtaac
    88981 ttcaaatccc actattgcaa aaagagaggg ttctattaat ttttttgaac gaatcaaaga
    89041 tgtaagagaa ttgattggct ctacaccctc tattcatgtt caggtgattt ctcaagattt
    89101 tgaaggcatc ttaaaggatg ctcatgaaat tcgaagacaa gcaggagatg atatatttat
    89161 caaagtacct gttactccag ctggattacg tgcaataaag gtgctaaaaa aagagggcta
    89221 ccatatcact gcaacagcta tttatacagt tattcaggga ttattagcta tcgaagcagg
    89281 agcggattac ctagctccat attataatag aatggaaaat ctgaacattg attcaaattc
    89341 tgtcattcgt caattagctc ttgctattga tagacagaac tctcctagta agattttagc
    89401 tgcatccttt aaaaatgtag cacaagtaaa taatgcttta gctgcaggtg cgcatgctgt
    89461 tacagcagga gcagatgttt ttgaatcagc tttcgccatg ccatctatcc aaaaggcggt
    89521 tgatgatttt tctgacgatt ggtttgttac tcaaaatagt cgttccattt agatagagag
    89581 gaaatacata tgagaatttt tgctagtcct tctagatata ttcaggggga aaatgccttg
    89641 tttgaaaatg ccaaatcaat tttggatttg ggaaattacc ctattctatt atgcgatcag
    89701 ttggtttatg atattgttgg aaaacgattt gaagattatc tacataggta tggtttccat
    89761 attgttctgg cgctatttaa tggtgaagct tctgacaatg aaatcaatcg agttgttgcc
    89821 ttggctgaga aagaaaattg tgatagtatt atcggtcttg gtgggggaaa gacgattgat
    89881 agcgcaaaag ctattgcaga tttgattgaa aagcctgtta ttattgctcc aacaattgca
    89941 tcgaccgacg cacctgtatc tgctttatct gttatttata cagatgaagg tgcatttgat
    90001 cattatctat tttattctaa aaatccagat ttagttttgg ttgatacaaa agttatttca
    90061 caagccccta agcgtctatt agcgtctggt attgcagatg gtttagcaac ttgggttgag
    90121 gcgcgtgcgg ttatgcaggc aaatggaaaa actatgttgg gacaacagca aacattggct
    90181 ggagttgcaa ttgcgaagaa atgtgaagaa acgctgtttg cagatggttt acaggctatg
    90241 gcagcttgtg aagctaaagt ggtgacacca gcattagaaa atattgttga agctaatact
    90301 ttattgagtg gtctaggttt tgaaagtgga ggattagctg cggcgcatgc aattcataat
    90361 ggttttactg cattgacagg tgacattcat catttaacac atggtgaaaa agtagcttat
    90421 ggaactttag tacaactatt attggaaaat agacctaaag aagaacttga taagtatatt
    90481 gagttttaca aaaaaattgg tatgccaaca actctaaaag aaatgcattt ggatcaagtt
    90541 ggatatgatg atttaataaa agttggtaaa caagcaacta tggagggtga gacaattcat
    90601 cagatgccgt ttaagatttc gccttcagat gttgctcaag ctattatcgc tgtagatgcc
    90661 tatgtaaatt caaaataaac aataaggact actgttttcc aaatggtagt cttttattga
    90721 tccctgtatt gaattctata gaagattgaa ataggatgag aacaaatcga ttgggaaagt
    90781 aaaattaatt tctataaatg ttttagcaat tgtttcgtac tatttcagat tcagtctact
    90841 atacgttctt cataaatcaa aaagcgacat aggtagtcgg ctatttattg tgaatacatt
    90901 aattagcatt ccagttttat cttcggtcta aaataagtat tttgtgctat acgagataag
    90961 cttcttgact tactccttga tttattcctt gatttactgc ataacaatgg gataaaaagt
    91021 gggagataga gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt
    91081 taaacacatt tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga
    91141 gaccatgagt ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga
    91201 acatcataca tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat
    91261 gttcccttat ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac
    91321 cgatatcctc agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg
    91381 ggatgctttt ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga
    91441 atttacagcg gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta
    91501 tgactgggat cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat
    91561 tttcaccaag ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt
    91621 tgaggaattg ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgagcg
    91681 tggaggctat ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta
    91741 cgcagagcgc ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat
    91801 gcaacgcaac tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac
    91861 agacaaggaa tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac
    91921 tgtcttggct cctgaacatg aattagtaga cgctatcaca agttcagagc aagcagaagc
    91981 tgtagcagac tataaacacc aagctagcct caaatctgac ttggctcgta cagaccttgc
    92041 caaagaaaaa actggtgttt ggactggtgc ttatgccatc aaccctgtca atggtaagga
    92101 aattccaatc tggattgccg actatgttct tgctagttac ggaacaggtg ccgttatggc
    92161 cgttccagct cacgaccaac gtgactggga atttgccaaa caatttgacc ttccaatcgt
    92221 cgaagtgctt gaaggtggaa atgtagcaga agctgcctat acagaggatg gtcttcatgt
    92281 caattcagac ttcctagatg gactcaacaa agaagaagct attgccaaga ttgtggcttg
    92341 gttggaagaa aaaggctgtg gacaagagaa ggttacctac cgtctccgcg actggctctt
    92401 tagccgtcaa cgttactggg gtgaaccaat tcctatcatt cattgggaag atgggacttc
    92461 aacagctgtt cctgaaagtg aattgccact tgtcttgcct gtaaccaagg atatccgccc
    92521 ttcaggtaca ggggaaagtc cattggctaa cttgacagat tggcttgaag tgactcgtgc
    92581 agatggtgtc aaaggtcgtc gtgaaaccaa cactatgcca caatgggcag gttcaagctg
    92641 gtactacctc cgctatattg acccacacaa tactgagaaa ttggctgatg aggatcttct
    92701 caaacaatgg ttgccagtag atatctacgt gggtggtgca gagcatgctg ttcttcactt
    92761 gctctacgct cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga
    92821 accattccaa aaactcttta accaaggaat gattttggga acaagctacc gtgaccaccg
    92881 tggggctctt gtggcaaccg ataaggttga aaaacgtgac ggttctttct tccatgtgga
    92941 aacaggagag gagttggagc aagcgccagc caagatgtct aaatctctta agaatgttgt
    93001 caacccagac gatgtggtgg agcaatacgg tgccgatacc cttcgtgtct atgaaatgtt
    93061 tatgggacca cttgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagccgtaa
    93121 attccttgac cgtgtttacc gtttgattac aagtaaagaa atccttgcgg aaaacaatgg
    93181 cgctcttgat aaggtttaca atgaaacagt caaatctgtc acagagcaaa ttgagtccct
    93241 caaattcaac accgccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga
    93301 caagctctat gttgactacg ccaaaggctt cgttcagttg attgcaccat ttgcacctca
    93361 cttggcagaa gagctctggc aaacagttgc ggcaacaggt gagtcaatct cttacgtgac
    93421 ttggccaaca tgggatgaaa gcaaattggt tgaagacgaa atcgaaatcg tcgtccaaat
    93481 caaaggtaaa gttcgtgcca aaatcatggt tgctaaagac ctatcacgcg aagaattgca
    93541 agagattgct ctagctgatg aaaaagtcaa agcagaaatt gatggtaagg aaatcgtgaa
    93601 agtgattgtg gtaccgaata aattggttaa tattgttgtg aaataaccaa tttatttgct
    93661 ggtttcaaat ctcggacagt ttcctaaact gtttgagcca gttaaactcg ttaatattgt
    93721 tttgaaataa gataggagtc cttcagagta gaatctgggg gattttttga atcttcttat
    93781 gaaagtatga tatactatgg gcaactataa agtttgaaaa gtgaaataag gagaataaga
    93841 tgccagtaaa tgaatatggt caaatgattg gggagtcaat ggaagcttat actccaggtg
    93901 aattgccttc ttttgatttc ttagaagggc gttatgctcg aatagaagct ctttcagtgg
    93961 aaaagcacgc ggaggattta ttagctgttt atggccctga tactcctcgg gagatgtgga
    94021 cctacctctt tcaggagcca gtggcaaatc tggaggagct ggttactctt ttaaatcaga
    94081 tgttggctcg taaggaccgt ttttactatg caattataga caaggcaact ggtaaggctt
    94141 tgggaacttt gtctctcatg cgtattgacc agaataaccg agtaatagaa gtgggagctg
    94201 tcactttttc tccagagctc agggggacac ggataggaac agaagctcag tatcttttgg
    94261 ctcgctatgt ctttgatgag cttaactatc gtcgctatga gtggaaatgc gatgctctta
    94321 acctgccatc cagacgagct gcggagcgtt tgggatttgt ctacgaagga acctttcgtc
    94381 aggcagtggt ttataagggg cgtacgaggg atacggattg gttgtctatg attgataagg
    94441 actggcctaa agtcaaatct cgtttggaaa tatggttgcg tcctgaaaac tttgataaaa
    94501 atggacagca gtacaagagc ttgagagaat tctaagaggt gttgagataa ttactattaa
    94561 aaagcaagaa attgtcaagc tagaggatgt tttgcatctc tatcaggctg tcggttggac
    94621 aaattatacc catcaacctc agatgctgga gcaggccttg tctcattcat tagtaattta
    94681 tctggcgctt gatggcgatg ctgtggtggg cttgattcgt ttggttggag atggtttttc
    94741 atcagttttt gtacaggatt tgattgtttt acctagctat cagcgccaag ggattggtag
    94801 ctccttgatg aaacaggctt tagaggattt taaagaggct tatcaagtcc agctggcgac
    94861 agaacagaca gaaaaaaatg taggatttta tcgttctatg ggttttgaaa ctttatccac
    94921 ctatgattgt acaggaatga tttgggtaaa caaagaaaaa taacaaaact tgttttttct
    94981 taagcaaagt ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt
    95041 tatttaataa aatcctaaac ttttttcatc acaatctcct aatgaagcca cccaatcagg
    95101 tggctttttt gcgtggtgag gtgctggtga tagaaatttt ttgcaaaata gtaaaatttt
    95161 agaaaagtta agctagtttt aagtttcgtc ttgtatcatg tagttattaa ataaagacct
    95221 cctaacttta tttaataaaa tcctaaactt ttctttttca taataatctc ccttaactcc
    95281 acccaatcag gtggagtttt ttagctctat ttcaggcttt tggggactat tctaaaaata
    95341 atttttcgat atttttcggt atttttcgga ttttggtcgg ggaattggcg gggacttttt
    95401 tagcgaatat aactaagaaa taggtctgtg gtcgcttcag ctagttcaaa ctcaatttga
    95461 ttgtaagtga ctgttaattg aagaactgga actactgtaa taatgatttt gcttgtctag
    95521 tagtggcgta ttaaatgaga agtgacatgt aagattgtct cttcgtttac gaaatcaaaa
    95581 tttctatgaa attgatagaa tccctaacgt tctcttaatc ttaaccgtct tgtcgtacag
    95641 cggttgaaga aaatgtaaac ctttgacaaa attcgtgaac tatgggataa taaaaaggaa
    95701 ttgagtacta gttctatatc ataggctaga aaagacccca agctcacgac caaataagct
    95761 tgaggtcttt tttgacacta tttgtccttg tttagccatt tatcgactat acgaagaacg
    95821 acaccgacca caattggtcc gatgatagtt ttgagtacta attccatcat gggctatctc
    95881 acctcctttc gtaggcggtg tagcagtgtc gtataatatt ataccacata agtgctaaac
    95941 ttaggagtca cccaatcagg tggctttttt gtttgtggct tggttttttg atataataga
    96001 gccatgagta gaattttaga taatgagata atgggggatg aggagttagt agaacgcacg
    96061 ctccgtcctc agtatttacg tgaatatatc ggacaggata aggtcaagga ccagctacaa
    96121 atctttattg aagctgccaa aatgcgggat gaagcgctgg atcatgtgct cttatttggg
    96181 cctccaggtc tcgggaaaac gaccatggcc tttgttattg ccaacgaact gggagtcaat
    96241 cttaagcaga cgtcgggtcc agtcattgaa aaagccggag atctggtagc tattttgaat
    96301 gagttagagc ctggggatgt actttttatt gatgagatcc atcgtttgcc aatgtcagtg
    96361 gaagaggtgc tttatagtgc tatggaggac ttctacatag atattatgat tggggctggt
    96421 gagggtagtc gtagtgttca tttggagtta ccacctttta ccttgattgg tgcgacgact
    96481 cgggctggta tgctctccaa tccgctacgg gcacgttttg ggattacagg ccatatggag
    96541 tattatgccc atgctgactt gacagaaatt gtcgagcgga cggcagatat ttttgagatg
    96601 gaaatcactc atgaggcagc atctgagttg gccctacgta gtcgtgggac ccctcgtatt
    96661 gccaatcgtc tcctcaagcg cgtgcgcgat tttgcccaga taatggggaa tggggtaatt
    96721 gatgatatta ttaccgataa ggctttgact atgctggatg ttgaccatga aggtttggac
    96781 tatgtggatc aaaaaatcct tcgtaccatg attgagatgt acagtggagg acctgttggt
    96841 ctaggaactc tttctgtgaa tatcgccgaa gagcgtgaga cagttgaaga tatgtatgag
    96901 ccttacttga ttcaaaaagg ttttatcatg cggacacggt ctggacgggt ggcgactgct
    96961 aaggcatatg agcacttagg ttatgaatac agtgaaaaat aagcaagaaa tcttagaggc
    97021 ttttagagaa aatccagata tgatggccat tctgacgatc atccgagacc ttggtctgaa
    97081 agactcgtgg ttggcagcag gttctgtcag aaatttcatc tggaatctct tgtcagacaa
    97141 atcacctttt gactttgaaa cagatgtaga tgtgattttc tttgatccgg atatttctta
    97201 tgaggaaacc ttattactgg agaaaaagct gagagaggat tttcctcagt accagtggga
    97261 attgaaaaat caggtctata tgcatcagca cagtcctcac actgctttct ataccagttc
    97321 tcgtgatgct atgagtaagt atccagaacg gtgtacggca gttggactgc gcttgaatga
    97381 agaatcagat tttgaactct atgtacctta tggtttggag gatattttga attttcaagt
    97441 tcgtccaact cctcatttct tagaaaatga agaccgaatg gaactctatc aaacacgttt
    97501 attcaagaaa aattggcagg agaaatggaa aaatttgatt tttaaaaata cttaaggaaa
    97561 ctttaagcta gggagtgtac actaagttca taagttaaga aaaccttaac ttaaactcct
    97621 aaaacttttt cataataatc tccctataaa aataaagtcg cccaatcagg cggcttattt
    97681 ttttgaaaaa tgggcttggt gcctgagaat aaatagctta gtgatagaag aaaatgggga
    97741 aatatggtat aatgaaacga tagatttttg aataggaata agatcatgtt tggatttttt
    97801 aagaaagata aggctgtgga agtagaggtt ccgacacagg ttcctgctca tatcggcatc
    97861 atcatggatg gcaatggccg ttgggctaaa aaacgtatgc aaccgcgagt ttttggacat
    97921 aaggcgggca tggaagcatt gcaaaccgtg accaaggcag ccaacaaact gggcgtcaag
    97981 gttattacgg tctatgcttt ttctacggaa aactggaccc gtccagatca ggaagtcaag
    98041 tttatcatga acttgccagt agagttttat gataattatg tcccggaact acatgcgaat
    98101 aatgttaaga ttcaaatgat tggggagaca gaccgcctgc ctaagcaaac ctttgaagct
    98161 ttaatcaagg ctgaggaatt gactaagaac aacacaggat tgattcttaa ttttgctctt
    98221 aactatggtg gacgtgctga gattacacag gcgcttaagt tgatttccca ggatgtttta
    98281 gatgccaaaa tcaacccagg tgacatcaca gaggaattga ttggcaacta tctctttacc
    98341 cagcatttgc ctaaggactt acgagaccca gacttgatta tccgtactag tggagaattg
    98401 cgtttgagca atttccttcc atggcaggga gcctatagtg agctttattt tacggacacc
    98461 ttatggcctg attttgacga agcagccttg caggaagcta ttcttgccta taatcgtcgc
    98521 catcgccgat ttggaggagt ttaggaggaa atatgaccca ggatttacag aaaagaacct
    98581 tgtttgcagg gattgccctg gctattttcc taccaatttt aatgattggg ggcctcttgt
    98641 ttcagatagc aatcggaatc atagccatgc tagccatgca tgaacttttg aagataagag
    98701 gtctagcgac catgacgatg gagggcctct tgactctctt tgcaaccttt gcattaacca
    98761 ttcccttgga gaattacctg acttttttgc cagttgatgg gaatgtggtt gcctatagtg
    98821 ttttgatttc aatcatgtta ggaacgaccg tttttagcaa gtcttatacg attgaggatg
    98881 cggttttccc tcttgctatg agcttctacg tgggctttgg atttaatgct ttactagatg
    98941 ctcgtgttgc aggtttggac aaggctctct tagccttgtg tatcgtctgg gcgacagaca
    99001 gtggtgccta tcttgttggg atgaactatg ggaaacgaaa gttagcacca agggtatcgc
    99061 ctaataaaac ccttgagggt gccttgggtg gtattttagg agcaatttta gtaaccatta
    99121 tctttatgat agttgacagt acagttgctc ttccatatgg aatttacaag atgtcagtct
    99181 ttgctatttt ctttagcatt gctggacaat ttggtgattt actagaaagt tcgatcaaac
    99241 gtcattttgg tgttaaggat tctgggaaat ttatccctgg acatggtggt gttttggatc
    99301 gtttcgatag tatgttgctt gtatttccaa tcatgcactt atttggactc ttttaatcaa
    99361 aagacggagg aaacgctatg ctcggaattt taacctttat tctggttttc gggattattg
    99421 tagtggtgca cgagttcggg cacttctact ttgccaagaa atcagggatt ttagtacgtg
    99481 aatttgccat cggtatggga cctaaaattt ttgctcacat tggcaaggat ggaacggcct
    99541 ataccattcg aatcttgcct ctgggtggct atgtccgcat ggccggttgg ggtgatgata
    99601 caactgaaat caagacagga acgcctgtta gtttgacact tgctgatgat ggtaaggtta
    99661 aacgcatcaa tctctcaggt aaaaaattgg atcaaacagc cctccctatg caggtgaccc
    99721 agtttgattt tgaagacaag ctctttatca aaggattggt tctggaagaa gaaaaaacat
    99781 ttgcagtgga tcacgatgca acggttgtgg aagcagatgg tactgaggtt cggattgcac
    99841 ctttagatgt tcaatatcaa aatgcgacta tctggggcaa actgattacc aattttgcag
    99901 gtcctatgaa caattttatc ttaggtgtcg ttgttttttg ggttttaatc tttatgcagg
    99961 gtggtgtcag agatgttgat accaatcagt tccatatcat gccccaaggt gccttggcca
   100021 aggtaggagt accagaaacg gcacaaatta ccaagattgg ctcacatgag gttagcaact
   100081 gggaaagctt gatccaagct gtggaaacag aaaccaaaga taagacggca ccgactttgg
   100141 atgtgactat ttctgaaaag gggagtgaca aacaagtcac tgttacaccc gaagatagtc
   100201 aaggtcgtta ccttctaggt gttcaaccgg gggttaagtc agattttcta tccatgtttg
   100261 taggtggttt tacaactgct gctgactcag ctctccgaat tctctcagct ctgaaaaatc
   100321 tgattttcca accggatttg aacaagttgg gtggacctgt tgctatcttt aaggcaagta
   100381 gtgatgctgc taaaaatgga attgagaata tcttgtactt cttggcaatg atttccatca
   100441 atattgggat ttttaatctt attccgattc cagccttgga tggtggtaag attgtgctca
   100501 atatcctaga agccatccgc cgcaaaccat tgaaacaaga aattgaaacc tatgtcacct
   100561 tggccggagt ggtcatcatg gttgtcttga tgattgctgt gacttggaat gacattatgc
   100621 gactcttttt tagataatcg aggaatatta tgaaacaaag taaaatgcct atcccaacgc
   100681 ttcgcgaaat gccaagcgat gctcaagtta tcagccatgc tcttatgttg cgtgctggtt
   100741 atgttcgcca agtttcagca ggtgtttatt cttatctacc acttgccaac cgtgtgattg
   100801 aaaaagctaa aaacatcatg cgccaagaat tcgaaaagat tggtgctgtt gagatgttgg
   100861 ctccaaccct tcttagtgca gaattgtggc gtgaatcagg tcgttacgaa acctatggtg
   100921 aagaccttta caaactaaaa aaccgtgaaa aatcagactt tatcttaggt ccaactcacg
   100981 aagaaacctt tacagctatt gtccgtgatt ctgttaaatc ttacaagcaa ttgccactca
   101041 acctttatca aattcagccc aagtatcgtg atgaaaaacg cccacgtaat ggacttcttc
   101101 gtacacgtga gtttatcatg aaggatgctt atagtttcca cgctaactat gatagtttgg
   101161 atagtgttta tgatgagtac aaagcagcct atgagcgtat tttcactcgt agtggtttag
   101221 acttcaaggc tattattggt gacggtggag ccatgggtgg taaggatagc caagaattta
   101281 tggccattac atctgctcgt acagaccttg accgctgggt tgtcttggac aagtcagttg
   101341 cctcatttga cgaaattcct gcagaagtgc aagaagaaat caaggcagaa ttgctcaaat
   101401 ggatagtctc tggtgaagat accattgctt actcaagtga gtctagctat gcagctaact
   101461 tagaaatggc aacaaacgag tacaaaccaa gcaaccgtgt tgtcgctgaa gaagaagtta
   101521 ctcgtgttgc aacgccagat gttaaatcaa ttgatgaagt tgcagccttc ctcaatgttc
   101581 cagaagaaca aacgattaaa accctcttct acattgcaga tggtgagctt gttgcagccc
   101641 ttctagttgg aaatgaccaa ctcaacgaag tcaagttgaa aaatcacttg ggagcagatt
   101701 tctttgacgt tgctagcgaa gaagaagtgg cgaatgttgt tcaagcagga tttggttcac
   101761 ttggaccagt tggtttgcca gagaatatta aaattattgc agatcgtaag gtgcaagatg
   101821 ttcgcaatgc agttgtcggt gctaacgaag atggctacca cttgactggt gtgaacccag
   101881 gccgtgattt tactgcagaa tatgtggata tccgtgaagt tcgtgagggt gaaatttccc
   101941 cagatggaca aggtgtcctt aactttgcgc gtggtattga gatcggtcat attttcaaac
   102001 tcggaactcg ctactcagca agcatgggag cagatgtctt ggatgaaaat ggtcgtgctg
   102061 tgccaatcat catgggatgt tacggtatcg gtgtcagccg tcttctttca gcagtgatgg
   102121 agcaacacgc tcgcctcttt gttaacaaaa cgccaaaagg tgaataccgt tacgcttggg
   102181 gaatcaattt ccctaaagaa ttggcaccat ttgatgtgca tttgattact gtcaatgtca
   102241 aggatgaaga agcgcaagcc ttgacagaaa aacttgaagc aagcttgatg ggagctggtt
   102301 atgaagtctt gacagatgac cgtaacgaac gtgtcggtgt taaatttagc gatagtgact
   102361 tgattggtct tccaatccgt atcactgttg gtaaaaaagc ggccgatggc attgtagaag
   102421 ttaagatcaa ggcaactggt gacaccattg aggttcatgc agataacgtg cttgaaacgc
   102481 ttgaaatcct aagcaagaaa taaaaactat aatcagaaga aaaacaagga aaaaatgtaa
   102541 ctagttttta ccttgttttt tctgtataat gggagaaatg agtagataaa gaggtaaatg
   102601 ttatgctaag atttccaaag gattttgtct ggggatcctc tacttctgga ccgcagacag
   102661 aaggacgtgt agctggtgac ggtaagggag acaatctctg ggattactgg ttccaagtgg
   102721 agccaaatcg ttactataat gggattggtt cagataagac atcgactttt tatgaaaatt
   102781 gggagcggga tattgagctt ttgttagaga ctggtcacac agtctttcgg acttctattc
   102841 agtggtcacg gatttttcca caaggctgtg gaaaagtcaa ccctcaaggt gtggattttt
   102901 atcgtaaggt ctttgaggct attaaggcta aaggaattcg tctgttagtc aatctctatc
   102961 attttgattt accttttgcc cttcaagagg atggtgatgg ttgggaaaat aaggcgacag
   103021 tctcagccta tgaagactat gctcgttttt gttttgagac ttatggagat ttagtggatc
   103081 aatggattac ctttaacgag cccatcgttc ctgtagaatt tggttatttt tatgatgccc
   103141 attatccaca taaggtggat gcagaggcag ctgttaaggt agcctatcat acacaattgg
   103201 ccagcagccg ggctgttaag gcttgccatg aacttttgcc tgattccaag attgggattg
   103261 tcctcaactt gacaccggct tatccacgta gccagcatcc tgctgatgtc aaggcagctc
   103321 gtattgcggc cctttttcag gcccaatctt tcttagatcc atctgtcttg gggacttatc
   103381 cacaggagtt ggtagaaatc ttgcatgaac acggtctttt acctgatgct acagaggaag
   103441 agttggaact cattcgtgat aatacggtgg acttccttgg tgtgaactac tatcaacctt
   103501 tgcgtgttat ggctcctcga tttgctaagc atccagagag tccactctta ccagaacatt
   103561 tttacgagcc ttatgtgatg cctggacgta aaatcaattc tcatcgtggt tgggagattt
   103621 atgagcaagg gatttatgac atcgcccaaa atatcaagga aaattatggc aatattgagt
   103681 ggatgttgac tgagaatggt atgggtgttg aaggggaaga aaaattccgt caagatggaa
   103741 tgattcaaga tgattaccgt attgactttg taaaaggtca tcttcgtgaa cttcaccgtg
   103801 ccattgaaga tggtgccaac tgtaagggct acttgatttg gacctttatt gactgctggt
   103861 catggctcaa cagctataaa aatcgctatg gtttggtcga attagacttg gaaacgcaag
   103921 aacgtcgtct gaagaaatca ggccactggt tcaaaaaatt aagcgataat aatggatttt
   103981 aaaaaggact ctgactgatt atcccaatcg gtcagagttt tttgcttaca ggagcttaat
   104041 ttgaactata ccaattttta ctcttgacaa gtgaaagaaa caagtatata ctgtttttgc
   104101 tgattctata aaagatgaat tagactatac caattttaag gagaaagcac agcttgcctg
   104161 tgtcgtatat actatgtgtg gaattgttgg tgttgttgga aacacaaatg caactgatat
   104221 tttgattcaa gggcttgaaa agcttgaata ccgtggctat gattctgcgg gaatttttgt
   104281 cctaggtggt gctgaaaatc acctagtcaa ggcggttggt cgtattgcag aattgtctgc
   104341 caagacagct ggtgttgagg gaacaactgg tatcggacat actcgttggg ctactcacgg
   104401 aaaaccaact gaggacaatg ctcacccaca ccgctctgag acagaacgtt ttgtcttggt
   104461 tcacaatggg gtgattgaaa actaccttga aatcaaggaa gaataccttg caggtcacca
   104521 cttcaagggg cagacagata ctgaaatagc cgttcatttg attggaaaat ttgcggaaga
   104581 agaagggctc tcagttcttg aagccttcaa aaaagccctt cacatcatcc gtggttctta
   104641 tgcctttgcc ttggttgact cacaagatcc tgaagtcatc tacgtagcta aaaataaatc
   104701 accacttttg attggtcttg gagaaggcta taacatggtc tgctcagacg ccatggctat
   104761 gattcgtgaa actaaccaat acatggaaat ccatgaccaa gagttggtaa tcgtcaaggc
   104821 tgatagtgtg gaagttcaag actatgatgg aaatcgtcgt gagcgtacta gctacactgc
   104881 tgaacttgac ttgtcagata tcggtaaggg aacttaccct tactacatgc tcaaggaaat
   104941 tgacgagcaa ccaactgtta tgcggaaact catccaagcc tacacagatg aggctggtca
   105001 agttgtcgta gacccagata tcattaaggc tgttcaagac gcagaccgca tctacatcct
   105061 tgcagctgga acatcttacc atgcaggatt tgcttctaag aaaatgttgg aagaattgac
   105121 agatacacca gttgaacttg gaatctcatc tgagtggggc tacggtatgc cacttctcag
   105181 caagaaacca ctcttcatct ttatcagcca atctggtgaa acagcggata gtcgtcaagt
   105241 tttggtcaag gctaatgaaa tgggaattcc aagcttaaca gtgacaaacg ttccaggttc
   105301 aaccctctca cgtgaagcca actataccat gctccttcac gcaggtcctg aaattgccgt
   105361 ggcatcaact aaagcctata cagcgcaaat cgcagccctt gccttccttg caaaagcagt
   105421 cggagaagca aatggtaatg ctaaagcgca agcctttgac ctggttcatg aattgtcaat
   105481 cgtagctcag tctatcgaat caactctttc agagaaagaa accattgaag ccaaggttcg
   105541 tgaacttctt gaaacaactc gtaacgcctt ttacatcgga cgtggtcaag attactacgt
   105601 agccatggaa gcaagtctca aactcaaaga gatttcttat atccagtgtg aaggttttgc
   105661 ggcaggagaa ctcaagcacg gaaccattgc cttgattgaa gaaggaacgc ctgtcttgtc
   105721 tctcttgtca gatccagttc ttgccaacca tactcgtgga aatatccaag aggtcgcagc
   105781 ccgtggtgcc aaagtcctca ctatcgcaga agagaatgta gccaaagata ccgacgatat
   105841 cgtccttacg accgtacatc catacctctc accaatttca atggtcgtac caacgcaatt
   105901 agtcgcttac tttgcaaccc tccaccgtgg cctcgatgtg gacaaaccac gtaaccttgc
   105961 caagtcagta acggtagaat aagctaaaaa agtctagtta tctaggcctt tttcttgtga
   106021 gcaaattggt tgcttgtact caagattcgt gttatactct tcgaaaatct cttcaaacca
   106081 cgtcaacgtc gccttgccgt aggtatggtt actgacttcg tcagttctat ccacaacctc
   106141 aaaacactgt tttgagcagc ctgcagctag cttcctagtt tgctctttga ttttcattga
   106201 gtattagaat aatttttcaa attgaagtac agagatagat aaggagaatc acaatggtag
   106261 aattgggaat ttcaacattt ggggaaataa cggagcttga agggactgga caaacttaca
   106321 gtcatgctga acgcattcgc cagttggtgg cagagattga gctggctgac aaggttggtt
   106381 tggacgtata tgggattggc gagcaccatc gggcggattt tgcagtatca gccccagaga
   106441 ttgtcctggc cgctggggca gtcaatacca agaaaatccg tttgaccagt gcagtcagca
   106501 ttctgtcaag catggatccg attcgtttgt tccaacagta tgccactatc gatgctttgt
   106561 caaatggacg atcggagatt atggctggaa ggggctcttt cacggaatct ttccctctgt
   106621 ttggttatga cttgaaagac tacgactctc tttttgatga gaaattagac ttgcttcagt
   106681 tagtcaatga aaagaccaag ttagactggc aaggtcgatt gactcaaacg attgctggta
   106741 aagaagttta tcctcgtcca gttcaggaca aattgccctt gtggatagct acaggtggtc
   106801 atgtcgaatc aacagtgaag attgctcagg ctggtctacc gattgtatat gctattattg
   106861 gtggtaatcc acgttatttt aaaaagttga ttcaggctta tcgtgagatt ggaagcgaag
   106921 cgggccatgc tgacaaagac ttgaaagtgg gagcccattc ttgggggtgg attgcggaag
   106981 atggtgagca ggcggtgaaa gattatttcc atccgactaa gcaagtggtg gatgctattt
   107041 ccaaagaccg tccgcactgg caggaattgc gttatgagca atatttggag caggtagggc
   107101 caaatggcgc catgtttgtt ggcaatccag atcaggtggc cgaaaaattg attcgcatga
   107161 tagaggattt aggattggac cgcttcatgc ttcatctacc gcttggttct atgcctcatg
   107221 accaggttct gagagctatt gaactcttcg gaacacaagt tgcacccaaa gtacgagctt
   107281 attttgctat gaaagaggct taataaaaaa tcctaatcaa gtttattagg acaacaaata
   107341 ttgtacaaaa attaatcccc cgagctataa tgcttggggg atttttctat aggagggcta
   107401 gtttagttct cttttttatt ttttagtaag aaaccgagac caaggagcgc aaggaggctg
   107461 attcctgcaa ataggagttt gttttcgttt ttgattcctg tatttggaag ttcagcttgt
   107521 ttatctgggg ttgcaggtat attttccttg ctagagtttt ctaccgattc gtttcgaacc
   107581 gcttctttta cagatgatgc ttgtgcttct tgtgctggtt gttcagcttg tgaatcagct
   107641 gtagcttggc taggtttatt ttccgcatca gctactttgg catctggttt agtagaatca
   107701 ggtctagctt ctggagctgg gtcttgatgt gcagggtgag aagcttcatt ttgatgttca
   107761 ggcttggaag gggttgagtc tggtttctct tctgcagttg actcatggct agttccattt
   107821 tgagagactc gaagaacagt agctgtaagg gcattcaatt tcaagccttt ttcagtccat
   107881 tcaagtcctt tcgggttggc aattccgact gatcctgctt ggttttcatc tgccaaaact
   107941 tccgcatttc ttagatgtgc aaaggcagtt cccaaattaa attcgcgagc tttttcatcc
   108001 gcattgacaa agactgcgta gatatcgccg tttggagcag tgatttggta gccaatcact
   108061 acatcctctt tttccacacc attttggcct gggacagtga tgaggtggac acggtctttg
   108121 atatcttgga gactcttaag tcggaaggca tctgtagatt gacgaagggc aatcaaacct
   108181 ttcatatagt cacggctctt gacattttca ggataagctt taccatctgt agccttagtc
   108241 cagtcaaact tgttgactgc gtcgctagaa tcgtaagaat catggatgaa gtaaggatag
   108301 tcaaatgggt tgccgtcctt atcacgcaac aagtgagatt tgtttggaac cttatcctct
   108361 gctactggag tcttgtaggc tgggtcacgg aattgtttag tacgtccata ttcctgaccg
   108421 gagtggataa atggagttcc ttgagctgtc aagaccatga gatttccaag tcgtaaacga
   108481 cggtggattt cagcatagtt ctcagccttg cttgggtctt ttttgataga ctgggcaatg
   108541 atgtcaaaga gggtcaagtt atcatgggct gcgatgtatt ggatgacatc tccagggctg
   108601 tcagcttcaa agttagttgg ttgagcaatg agatttttaa agatggtgtt gacatcacgc
   108661 ttgccacctg tgataaaggc aggttgacct tcgtttggat aaccagattt gaggttgtta
   108721 cggatgtcat ctgaaaagac agcgacagta tcggtatgtt tcatccaatc ttggtcagca
   108781 gctttagtag gcatgttttc atcaccggca taggttctcc aaccttcacc aagcatgatg
   108841 aggtttggat tgagggcgcg tgcagccttg taagcttctt cgatagaagc ggcgtcatgg
   108901 tctcccatca tatcgaagcg gaagccatcc actttgtagg tatcaactag gtatttgata
   108961 gagtcaacta ggagccgttt ggtcatatgg tgggttgtcc ccaagcgtcc accaccaaag
   109021 ctagttcgag gtgtgccatc ggcatccata aagtggtagt agtttggctc taggtcttca
   109081 aagatatcga ctttggctgt gtggttataa acgacatcta ggatagctcc cataccacgt
   109141 ttgtggattt cgttgatgag gtttttaaat tctgcgattc gtttttctgg attcttagga
   109201 tcgcttgagt acataccagt caaggagaag tagttttgag ggtcatatcc ccagttgtag
   109261 ttgctgttgc ttgaagcgta gtcagacaag cgttcatggt ttttcaattc attgacaaag
   109321 tagtaagaca agactggaag gagctggata tgggttacac ccaagtcttt gagatagtct
   109381 agtttttcaa tgaaggcttc aaaagtccca aatggtttgg tcaagtcttt tgcaatggca
   109441 ggatctgaag tgaagtcacg cacatgagct tcgtagataa cggcgtcttc acgagtcttg
   109501 aaattgtgaa tcttaccata agtcaagtct tgaggtccga gtttagctgg atctacaaag
   109561 gcggctttag ccactttatg ggcatcgtca attttggcat cgtcgctatt ccaagcagca
   109621 agagatttag cgtaaggatc gagtgcaaga acagttttac cttgacgctc gatttggtat
   109681 tgataatagt agccagtgaa atctgtgatt ccgagtttgt ttgtgctgtc tagagtttgt
   109741 ttccaagttc ctctttcccc tttttcgaga gcgacagttc caactacttt gtcagggtca
   109801 ttcttgtcgt agacaacaac agaaacctta tcagcacttg gtgaccaaag ggtcaaatca
   109861 acttgttttc cttcttcttt taggtcagct cccagtttgc catcatagct gtatgtctca
   109921 tctttcaggc gccagcttgt tttggtagtg aattggtcgg aattgtagct aacagtataa
   109981 ggatgttttg tgtcagagaa atctccgctg taggtcactt tcttaccagc ttcatcgatt
   110041 gcaacatcgg taatagttac cttgtttcct aggtgattag tgatgttgga gtgtttgagg
   110101 atatcttctt ttttagcacc gacaagtgtt gaaaagctac tttcaatgct agaagtgcct
   110161 acgtgttggg ctcctgtcat acggatatca tggacatagt atggatttgt gtaaatcgat
   110221 tcatcatcgt cttttaggaa aatttggcta tgatttttca aatctgtgaa cttataattt
   110281 tctttacgga ttttcacgtc gtctccttgt ttgctctcat ctagtaataa aaatccaaat
   110341 tctcttgcgg cttcattaag aggaatgtcg atatagcggc catatttgcc tgtagccgta
   110401 aagtctgttc cgtcaggcca ttgagcgcta cttggatttt ttacatctcc ccagtaccag
   110461 agagatttct tgtcatagtt gccatctgtg cggtagtagt tgacgcgaac agttcctgca
   110521 ggctgtggct cgtaagagaa aaccttgtaa tcttggtcta accaagcctc gttcattttt
   110581 ggaactagtt tttctacaga tttatcgccg gttagatttt ttccagctgt attgttgatg
   110641 aggaagctaa ttttcttggc ttgttctccc tttaatttga catctaggta atagccgtag
   110701 tcatctttct tggcatcctt gaaggacaaa gctccgtttg gccagttttc agatggtttt
   110761 tcaacatcgt cccaagtcca tagtccttga gcatccttgt tttcttcagg aagttttttg
   110821 acatggatac ggaagtagtt atcttcgatg ggctcttctg ccttagtttc agttgttact
   110881 ggactagtag aagtagttgg ctctgttgca ggtttttctt ctgttttctc tagggaagcg
   110941 tttgcatttc taggtgaaga aatatcactt tcgttcttac cagagccagc tgctgtatca
   111001 gtaagaggtt gggcaagggt ggttgtattt ctgttgttgg gttcgttagt ggttggtgta
   111061 ctttcgtcgg atgagatagt tggtgtagcc atggcaagca agacaaggct tgcgccgata
   111121 aggacagaac cagttccatt tttgagggaa cggatgctgt agaccatttt tttctcagtg
   111181 tgagatggtg tttttctcat aatgattctc caatcaataa atttctatat cagtatagca
   111241 tgtagtaaaa caatatgcaa gcgttttctt tgatttgtga aaaaaattct tacttttgag
   111301 aagttttctg tactatttta tatatcagta taaatgacgg agataaaaat gtcacataag
   111361 ccaagccgta ttattaggaa gatgatgtgt tcccagctat ttttattcag aaattgatct
   111421 ctaacattac caataaaaaa gaaaaatatc ttgacaagca agggaaaatt ttgttacaat
   111481 aatagacggt actttttact tttggtctct caagagtgta cagggacgtg ctgacaaatg
   111541 ttgcaaaagt acacacagat gatatctgtc accaagtgta tcatcaccaa aaataaaaaa
   111601 acacaggaga atgtagatgc ctacaattaa ccaattggtt cgcaaaccgc gtaaatcaaa
   111661 agtagaaaaa tctaaatcac cagctttgaa cgttggttac aatagtcata aaaaagttca
   111721 aacaaacgtt tcttcaccac aaaaacgtgg tgttgcaact cgtgttggaa caatgacacc
   111781 taaaaaacct aactcagccc ttcgtaaatt cgctcgtgta cgtttgagca accttatcga
   111841 agttactgcc tacatcccag gtatcggaca caacttgcaa gagcacagcg tggtgcttct
   111901 tcgcggtgga cgtgtaaaag accttccagg ggtacgttac catatcgtcc gtggtgcact
   111961 tgatactgca ggtgttaacg atcgtaaaca aggtcgttct aaatacggta ctaaacgtcc
   112021 aaaagcataa ggaaagggga taaagagaaa tgagtcgtaa aaatagagct ccaaaacgtg
   112081 acgtattgcc agatccgcta tacaattcac aactagttac tcgtcttatc aaccgcgtta
   112141 tgcttgatgg taaacgtggt actgctgctt caatcgttta cggtgctttt gagcaaatca
   112201 aagaagctac tggcaacgat gcacttgaag tatttgaaac agctatggaa aacatcatgc
   112261 ctgtacttga agtacgtgca cgtcgtgttg gtggttctaa ctaccaagtc ccagttgaag
   112321 ttcgtccaga acgtcgtaca acacttggac ttcgttggtt ggtaacaatc gctcgtcttc
   112381 gtggtgaaca cacaatgcaa gaccgtcttg caaaagaaat cttggatgct gctaacaaca
   112441 ctggtgcagc agttaagaaa cgtgaagata ctcaccgtat ggctgaagct aaccgtgcat
   112501 tcgcacactt ccgttggtaa gataggatgc gaaagcgtta agaaagtccc agagaaaata
   112561 gggaatcgaa gcaggttgcg gttgcaacca atgagattca tctttttctc cagactttta
   112621 gcttgagctc aactaaatca tgatgctagg aacggtaagg atgcaaggtg aaaataggaa
   112681 actgacgcag tattcgacga atacaaggag ttttatcttt ttcacgcagc atcccgttcc
   112741 agctcacatc ggctaactaa ctttagcccg ggttcaaatt agctaaatcg attagtatta
   112801 gctataactc agcttaccat ctcgtaagtt gaaaccaaca atagcatgaa aacattgaga
   112861 acgggtaggt cctgcctatc cgtttttatt aaaatcgtgt tataatagaa tagaaatcaa
   112921 aaataaatag gagaaacaaa cctcatggca cgcgaatttt cacttgaaaa aactcgtaat
   112981 atcggtatca tggctcacgt cgatgccggt aaaacaacaa ctactgagcg tattctttac
   113041 tacactggta aaatccacaa aatcggtgaa actcacgaag gtgcgtcaca aatggactgg
   113101 atggagcaag agcaagaacg tggtatcacg atcacatctg ctgcgacaac agctcaatgg
   113161 aacaaccacc gcgtaaacat catcgacaca ccaggacacg tggacttcac aatcgaagta
   113221 caacgttctc ttcgtgtatt ggatggtgcg gttaccgttc ttgactcaca atcaggtgtt
   113281 gagcctcaaa ctgaaacagt ttggcgtcaa gcaactgagt acggagttcc acgtatcgta
   113341 tttgccaaca aaatggacaa aatcggtgct gacttccttt actctgtaag cacacttcac
   113401 gatcgccttc aagcaaatgc acacccaatc caattgccaa tcggttctga agatgacttc
   113461 cgtggtatca ttgacttgat caagatgaaa gctgaaatct atactaacga ccttggtacg
   113521 gatatccttg aagaagacat cccagctgaa taccttgacc aagctcaaga ataccgtgaa
   113581 aaattgattg aagcagttgc tgaaactgac gaagaattga tgatgaaata cctcgaaggt
   113641 gaagaaatca ctaacgaaga attgaaagct ggtatccgta aagcgactat caacgttgaa
   113701 ttcttcccag tattgtgtgg ttcagccttc aaaaacaaag gtgttcaatt gatgcttgat
   113761 gcggttatcg actaccttcc aagtccactt gacatcccag caatcaaagg tattaaccca
   113821 gatacagacg ctgaagaaac tcgtccagca tctgacgaag agccatttgc agctcttgcc
   113881 ttcaagatca tgactgaccc attcgtaggt cgtttgacat tcttccgtgt ttactcaggt
   113941 gttcttcaat caggttcata cgtattgaat acttctaaag gtaaacgtga acgtatcgga
   114001 cgtatccttc aaatgcacgc taacagccgt caagaaatcg acactgttta ctcaggtgat
   114061 atcgctgctg ccgttggttt gaaagatact acaactggtg actcattgac agatgaaaaa
   114121 tctaaaatca tccttgagtc aatcaacgtt ccagaaccag ttatccaatt gatggttgag
   114181 ccaaaatcta aagctgacca agacaagatg ggtatcgccc ttcaaaaatt ggctgaagaa
   114241 gatccaacat tccgcgttga aacaaacgtt gaaactggtg aaacagttat ctcaggtatg
   114301 ggtgaacttc accttgacgt ccttgttgat cgtatgcgtc gtgagttcaa agttgaagcg
   114361 aacgtaggtg ctcctcaagt atcttaccgt gaaacattcc gcgcttctac ccaagcccgt
   114421 ggattcttca aacgtcagtc tggtggtaaa ggtcaattcg gtgatgtgtg gattgaattt
   114481 actccaaacg aagaaggtaa aggattcgaa ttcgaaaacg caatcgtcgg tggtgtggtt
   114541 cctcgtgaat ttatcccagc ggttgaaaaa ggtttggtag aatctatggc taacggtgtt
   114601 cttgcaggtt acccaatggt tgacgttaaa gctaagcttt atgatggttc atatcacgat
   114661 gtcgactcat ctgaaactgc cttcaagatt gcggcttcac tttcccttaa agaagctgct
   114721 aaatcagcac aaccagctat ccttgaacca atgatgcttg taacaatcac tgttccagaa
   114781 gaaaaccttg gtgatgttat gggtcacgta actgctcgtc gtggacgtgt agatggtatg
   114841 gaagcacacg gtaacagcca aatcgttcgt gcttacgttc cacttgctga aatgttcggt
   114901 tacgcaacag ttcttcgttc tgcatctcaa ggacgtggta cattcatgat ggtatttgac
   114961 cactacgaag atgtacctaa gtcagtacaa gaagaaatta ttaagaaaaa taaaggtgaa
   115021 gactaatccg tcctcactct agaaggaagt cacttagtgg cttccttttg tctttagaaa
   115081 atacctctaa atatggtaaa atagtagaag aataatgtga ggaaaatgaa tgtcaaatag
   115141 ttttgaaatt ttgatgaatc aattggggat gcctgctgaa atgagacagg ctcctgcttt
   115201 agcacaggcc aatattgagc gagttgtggt tcataaaatt agtaaggtat gggagtttca
   115261 tttcgtattt tctaatattt taccgattga aatcttttta gaattaaaga aaggtttgag
   115321 cgaagaattt tctaagacag gcaataaagc tgtttttgaa attaaggctc ggtctcaaga
   115381 attttcaaat cagctcttgc agtcctacta tagggaggct ttctctgaag gtccatgtgc
   115441 tagtcaaggt tttaagtccc tttatcaaaa tttgcaagtt cgtgctgagg gtaatcagct
   115501 atttattgaa ggatctgaag cgattgataa ggaacatttt aagaagaatc atcttcctaa
   115561 tttagccaaa caacttgaaa agtttggttt tccaactttt aactgtcaag tcgagaagaa
   115621 tgatgtcttg acccaagagc aggaagaggc ctttcatgct gaaaatgagc agattgttca
   115681 agctgccaat gaggaagcgc tccgtgctat ggaacaactg gagcagatgg cacctcctcc
   115741 agcggaagag aaaccagtct ttgattttca agcgaaaaaa gctgcagcta aacccaagct
   115801 ggataaggcg gagattactc ctatgatcga agtgacgaca gaggaaaatc gtctggtatt
   115861 tgaaggggtt gtttttgatg tggagcaaaa agtgactaga acaggtcgtg ttttaatcaa
   115921 ctttaaaatg acggactata cttcaagttt ttctatgcaa aagtgggtta aaaacgagga
   115981 agaggcccag aagtttgacc tcatcaagaa gaattcttgg ctccgagttc gagggaatgt
   116041 ggagatgaat aacttcacac gcgatttgac tatgaacgta caggatctgc aggaagttgt
   116101 tcactatgag cggaaggatt tgatgccaga aggtgagcgt cgggttgagt ttcatgctca
   116161 tactaacatg tcgactatgg atgctttgcc agaggtcgaa gagattgttg caacagctgc
   116221 taagtgggga cacaaggcgg ttgctatcac ggaccatggg aatgtccagt cctttccaca
   116281 tggctataag gcggctaaga aagcgggaat ccagctgatc tatggaatgg aagccaatat
   116341 cgtggaggac cgtgtcccta tcgtctataa cgaagtggag atggacttgt cagaagcaac
   116401 ctacgtggtc tttgacgtgg aaacgacggg actttcagct atctataatg acttgattca
   116461 ggttgcggcc tctaagatgt acaaggggaa tgttattgct gaatttgatg aatttatcaa
   116521 tcctgggcat cccttgtcag cttttactac agagttaact ggaattacag atgatcatgt
   116581 caaaaatgcc aaaccactag aacaagtttt gcaagaattc caagaatttt gcaaggatac
   116641 ggtcctagtt gcccacaatg ctacctttga cgttggcttt atgaatgcta attatgagcg
   116701 tcatggtctt ccaaagatta gtcagccagt tattgatacg ctggagtttg ctagaaacct
   116761 ctatcctgag tataaacgcc atggtttggg gcctttgacc aagcgttttg gtgtggcctt
   116821 ggaacatcat cacatggcca actacgatgc ggaagcgact ggtcgtctgc ttttcatctt
   116881 tatcaaagag gtagcagaaa aacatggtgt gaccgattta gctagactca acattgatct
   116941 aatcagtcca gattcttaca aaaaagctcg gatcaagcat gcgaccatct atgtcaagaa
   117001 tcaggtaggt ctaaaaaata tctttaagct ggtttccttg tctaatacca agtattttga
   117061 aggagtgcca cggattccga gaacggttct agatgcccat cgagagggct tgattttagg
   117121 ttcagcctgt tcagagggtg aagtttttga cgtggtcgtt tctcaaggtg tggatgcggc
   117181 ggttgaggtg gccaagtatt atgactttat cgaggtcatg ccaccggcta tctatgcgcc
   117241 cttgattgcc aaagagcagg tcaaggatat ggaggaactc cagaccatta tcaagagttt
   117301 gatagaggtt ggagatcgcc ttggcaagcc tgttctggct acgggaaatg ttcactatat
   117361 cgaaccggaa gaagagattt atcgtgaaat tatcgtccgt agtttgggac agggtgcgat
   117421 gattaaccga actatcggtc atggtgaaca tgcccaacca gcaccacttc caaaggctca
   117481 ttttcgaacg actaatgaga tgttggatga atttgccttt ttgggagagg aactggctcg
   117541 taaactggtt attgaaaaca ccaatgcctt ggcagaaata tttgaacccg ttgaagtcgt
   117601 taagggtgac ttgtatacgc ctttcatcga caaggctgaa gaaacagttg ctgagttgac
   117661 ctataagaaa gcttttgaga tttatggaaa tccgctgcca gatattgttg atttgcggat
   117721 tgaaaaagaa ttaacatcca tactggggaa tggatttgct gtgatttatc tggcatcgca
   117781 gatgctggtg caacgttcta atgaacgggg ttatttggtt ggttctcgtg ggtctgtcgg
   117841 atctagtttc gttgcgacca tgattgggat tacggaagtc aatcctctct ctcctcacta
   117901 tgtctgtggt cagtgtcagt acagtgagtt tatcacagat ggttcgtacg gttcaggatt
   117961 tgatatgccc cataaggact gtccaaactg tggtcacaaa ctcagtaaaa acggacagga
   118021 tattccgttt gagaccttcc ttggttttga tggggataag gttcctgata ttgacttgaa
   118081 cttctcggga gaagatcagc ctagcgccca cttggatgtg cgtgatatct ttggtgaaga
   118141 atatgccttc cgtgcgggaa cggttggtac ggtagctgcc aagactgcct atggatttgt
   118201 caagggttac gagcgagatt atggcaagtt ttatcgtgat gcagaagtag aacgcctcgc
   118261 tcaaggagcg gcgggtgtca agcggacaac aggccaacac ccggggggaa tcgttgttat
   118321 tccgaactac atggatgtct acgattttac gcctgtccag tatccagcag atgatgtcac
   118381 ggctgaatgg cagaccactc actttaactt ccacgatatc gatgagaacg tcctcaaact
   118441 cgatgtactg ggacatgatg atccgaccat gattcgaaaa cttcaggatt tgtctggtat
   118501 tgaccctaat aaaattccta tggatgacga aggcgtgatg gcactctttt ctgggactga
   118561 tgtgctaggg gtaacacctg aacaaattgg aacgcctacg ggtatgttgg ggattccaga
   118621 gtttggaaca aatttcgtac gtggaatggt agacgaaacc catccgacaa cctttgcgga
   118681 attgcttcag ctgtctggtc tgtcccacgg tactgacgtt tggttgggga atgctcagga
   118741 tctgattaag caaggaatag cggacctatc gactgttatc ggttgtcggg acgacatcat
   118801 ggtttacctc atgcatgcgg gtctggaacc taagatggcc tttaccatta tggaacgggt
   118861 acgtaagggt ttgtggctaa agatttcaga agaggagaga aatggctata tcgaagccat
   118921 gaaggctaat aaggtgccag agtggtatat cgaatcctgt gggaaaatta agtacatgtt
   118981 ccctaaggcc catgcggcag cctacgttat gatggccttg cgtgtagctt acttcaaggt
   119041 tcaccatcct atttattact actgtgctta cttctccatt cgtgctaagg cttttgatat
   119101 caagaccatg ggtgcgggct tggaggccat caagcgcaga atggaagaaa tctctgaaaa
   119161 acggaagaac aatgaagcct ctaatgtgga aatcgatctc tatacaactc ttgagattgt
   119221 caatgagatg tgggaacgag gtttcaagtt tggcaaatta gatctctacc gtagtcaggc
   119281 gacagagttc ctcatcgacg gggataccct tatcccacca tttgtagcaa tggatggtct
   119341 gggagagaac gttgccaagc aactggtgcg ggcgcgtgaa gagggagaat tcctctctaa
   119401 aacagaacta cgcaagcgtg gtggactctc atcaaccttg gttgaaaaga tggatgagat
   119461 gggtattctt ggaaatatgc cagaggataa ccagttgagt ttgtttgatg agttgtttta
   119521 aaaaattgct taataatcta ttaaaagagg ctaacgtata tccaatagat ttacattagc
   119581 tttctttttt gttaaaatag tctatggaaa gagggtgaga gtatgtcaaa gatgagtata
   119641 agcatccgtc tggatagtga ggttaaggag caggcccaac aggtgtttag taatctggga
   119701 atggatatga caacagctat taatattttc cttcgtcagg caattcaata tcagggatta
   119761 ccttttgatg ttagactaga cgaaaatcgg aagttgctcc aagcgttaac ggatttagac
   119821 taaaatcgta atatgagcca gtcttttgaa tcagtctcag atttgatgga ggacttacgt
   119881 gcttaagatt cgctatcata aacagtttaa aaaagatttt aagttggcta tgaagcgtgg
   119941 tttgaaggca gaattattag aagaagtttt gaattttctg gttcaagaaa aagaacatcc
   120001 taccagatat cgtgatcatt cattgacggc atccaagcat tttcaaggag ttcgtgaatg
   120061 ccatacccag ccagattggc ttttggttta taaagtagac aagtcggaat tgattttaaa
   120121 tttgctgagg acaggcagtc acagtgattt attttaatct attttaaggg ggttctcatg
   120181 aaactaagaa tatttgcgga agataagccg gctaagaagg tatttgaata tcaattagaa
   120241 cttgctgatc gtacaattct tctatcaaca gcactcttgt caggtgctat tgctttagcg
   120301 ggattattct ctgctttgaa agaaaaataa aaatagaaaa gagaaaatta catggtttta
   120361 ccaaatttta aagaaaatct agaaaaatat gcgaaattgt tggttgcgaa cggaattaac
   120421 gtgcaacctg gtcacacttt ggctctctct attgatgtgg agcaacgtga attggcacat
   120481 ctaatcgtga aagaagctta tgccttgggt gcgcatgagg tcatcgttca gtggacagat
   120541 gatgtgatta accgtgagaa atttctccat gccccgatgg agcgtttgga caatgtgcca
   120601 gaatacaaga ttgctgagat gaactatctc ttggagaata aggctagccg tcttggagtt
   120661 cgttcatctg atccaggtgc cttgaacgga gtggacgctg acaagctttc agcttctgct
   120721 aaagctatgg gacttgccat gaagcctatg cgtatcgcaa ctcaatctaa caaggttagc
   120781 tggactgtag cagctgcagc aggacttgag tgggctaaga aagtcttccc aaatgctgcg
   120841 agcgacgaag aagcagttga tttcctttgg gaccaaattt tcaaaacttg ccgtgtctac
   120901 gaagcagatc ctgttaaggc ctgggaagag catgcagcta tcttgaagag caaggccgat
   120961 atgcttaata aggagcaatt ttcagccctt cactacacag cgccaggaac agatttaaca
   121021 cttggtttgc caaagaacca cgtttgggaa tcagctggtg ctgtcaatgc acagggcgaa
   121081 ggattcttgc caaatatgcc gacagaagag gtcttcacag cgcctgactt ccgtcgtgca
   121141 gatggttatg tcacttctac aaaaccgctt agctacaacg gaaatatcat cgaaggtatt
   121201 aaggtaacct ttaaggatgg acaaatcgta gatatcactg ctgagaaggg tgatcaggtt
   121261 atgaaagacc ttgtctttga aaatgcgggt gcgcgtgcct tgggtgaatg tgccttggta
   121321 ccagatccaa gtccaatttc tcagtcaggc attaccttct ttaacaccct tttcgatgaa
   121381 aatgcgtcaa accacttggc tatcggtgca gcctatgcga ctagcgttgt tgatggagcg
   121441 gagatgagcg aagaggagct tgaagctgca gggcttaacc gttcagatgt tcacgtagac
   121501 tttatgattg gttctaacca aatggatatc gatggtattc gtgaggatgg aacgcgagta
   121561 cctcttttcc gtaatgggaa ttgggcaaat tagcaaaaat atcccaaaag caaattgaat
   121621 tgtaagtatg cttttgggat atttatttat aagattttat tagattttga acgattacat
   121681 ttccaacaga gagtttgaag attgtcaggt gtggaaagtc ctccttttga tacagggaca
   121741 atatggtcta tctcaagtaa caggagagat tgttcagctg tagaggcagc acagatttga
   121801 caagtatagt ggtctctttc ttttatttga gttcgaagtt tgtttgtcat cagtgatcgt
   121861 tgagcttgag cagtttgttt tgattttatt ttctttgcaa tatactctgc tgttgcttca
   121921 acagtttcac cgttaaacag aattgtcgtt ttctgagaac tattgcctcc tgcactcacg
   121981 tattcaaaaa tataagaagt gtaatcaacc tttatgtctg gtaggtggat atctaactct
   122041 ttcattaaat ctttagaaaa gtattttaaa ataaattttg gaggattaaa gtcggttttt
   122101 atttgtttct ctcgttgata aagattatca attgtgtttt ccattcgaga gatattctct
   122161 ccgatttctt caagctgttt caagctttct tcggttgcag ttattccgaa atacttacag
   122221 agataatgta taggttcttc agatgcacgt cgcacaactt gtagggaagt tgaataaacg
   122281 ttactttgat ttaaagtttt cttatgttta tctcgtttat agtcatgttg gctagtattt
   122341 tcaaagtgag ctaaatgtgc atgtttccca gtaatatcct ttacaataaa ttgattttta
   122401 tttgggatat cttttacata ttctgaaatt tcattaaact caataatagt atctgcaatt
   122461 ttttgttttt gttctagaaa acctggactt ttaaaatatc ttatttttct aatatgtaaa
   122521 gatataccat
//
LOCUS       DAVMBH010000002        83033 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVMBH010000002 DAVMBH010000000
VERSION     DAVMBH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.002"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..199
                     /gene="tnpB"
                     /locus_tag="VYP30_000137"
     CDS             <1..199
                     /gene="tnpB"
                     /locus_tag="VYP30_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1807201.1"
                     /translation="QVFLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDV
                     KALAPEQVDWLMKGFSITPQI"
     gene            complement(340..648)
                     /locus_tag="VYP30_000138"
                     /pseudo
     CDS             complement(340..648)
                     /locus_tag="VYP30_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            639..1037
                     /locus_tag="VYP30_000139"
     CDS             639..1037
                     /locus_tag="VYP30_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1807202.1"
                     /translation="MKSPIPKAPLANNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVVIDLFISYFNPL"
     gene            complement(1234..2154)
                     /gene="cysK"
                     /locus_tag="VYP30_000140"
     CDS             complement(1234..2154)
                     /gene="cysK"
                     /locus_tag="VYP30_000140"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1807203.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(2439..3074)
                     /locus_tag="VYP30_000141"
     CDS             complement(2439..3074)
                     /locus_tag="VYP30_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1807204.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            3130..4428
                     /locus_tag="VYP30_000142"
     CDS             3130..4428
                     /locus_tag="VYP30_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1807205.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            4425..5087
                     /locus_tag="VYP30_000143"
     CDS             4425..5087
                     /locus_tag="VYP30_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1807206.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            5167..5715
                     /gene="raiA"
                     /locus_tag="VYP30_000144"
     CDS             5167..5715
                     /gene="raiA"
                     /locus_tag="VYP30_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1807207.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5851..7824
                     /locus_tag="VYP30_000145"
     CDS             5851..7824
                     /locus_tag="VYP30_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1807208.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENNETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKSLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7821..8273
                     /gene="rplI"
                     /locus_tag="VYP30_000146"
     CDS             7821..8273
                     /gene="rplI"
                     /locus_tag="VYP30_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1807209.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            8317..9669
                     /gene="dnaB"
                     /locus_tag="VYP30_000147"
     CDS             8317..9669
                     /gene="dnaB"
                     /locus_tag="VYP30_000147"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1807210.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9671..9937
                     /locus_tag="VYP30_000148"
     CDS             9671..9937
                     /locus_tag="VYP30_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807211.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            10026..11372
                     /gene="cbpD"
                     /locus_tag="VYP30_000149"
     CDS             10026..11372
                     /gene="cbpD"
                     /locus_tag="VYP30_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1807212.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     VKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      11455..11557
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11628..11918
                     /locus_tag="VYP30_000150"
     CDS             11628..11918
                     /locus_tag="VYP30_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1807213.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11881..12639
                     /locus_tag="VYP30_000151"
     CDS             11881..12639
                     /locus_tag="VYP30_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807214.1"
                     /translation="MRNLRSILRRHISLLGFLGVLLIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            12678..13685
                     /locus_tag="VYP30_000152"
     CDS             12678..13685
                     /locus_tag="VYP30_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1807215.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13685..14413
                     /locus_tag="VYP30_000153"
     CDS             13685..14413
                     /locus_tag="VYP30_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807216.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            14532..14990
                     /locus_tag="VYP30_000154"
     CDS             14532..14990
                     /locus_tag="VYP30_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1807217.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14992..17424
                     /locus_tag="VYP30_000155"
     CDS             14992..17424
                     /locus_tag="VYP30_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1807218.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            18066..18719
                     /gene="rr06"
                     /locus_tag="VYP30_000156"
     CDS             18066..18719
                     /gene="rr06"
                     /locus_tag="VYP30_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1807219.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18716..20047
                     /gene="hk06"
                     /locus_tag="VYP30_000157"
     CDS             18716..20047
                     /gene="hk06"
                     /locus_tag="VYP30_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1807220.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDENGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVSNILESYQMDYSFLPYEHGMEFKISL"
     gene            20142..20669
                     /locus_tag="VYP30_000158"
     CDS             20142..20669
                     /locus_tag="VYP30_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1807221.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20748..23414
                     /gene="pspC"
                     /locus_tag="VYP30_000159"
     CDS             20748..23414
                     /gene="pspC"
                     /locus_tag="VYP30_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1807222.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGIT
                     QVATSYNKANESQTEHRKAAKQVDEDIKKMLSEIQEYIKKMLSEIQLDKRKHTQNVNL
                     NRKLSAIQTKYLYELRVLKEKSKKEELTSKTKKELDAAFEKFKKEPELTKKLAEAKQK
                     AKAQKEEDFRNYPTNTYKTLELEIAEFDVKVKEAELELVKEEAKPRNEEKIKQAKAKV
                     ESKKAEATRLEEIKTERKKAEEEAKRKAEESEKKAAEAKQKVDTKEQGKPKRRAKRGV
                     SGELATPDKKENDAKSSDSSVGEETLPSPSLNMANESQTEHRKDVDEYIKKMLSEIQL
                     DRRKHTQNVNLNIKLSAIKTKYLYELSVLKENSKKEELTSKTKAELTAAFEQFKKDTL
                     KPEKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKKAELELV
                     KEEANESRNEEKIKQAKEKVESKKAEATRLEKIKTDRKKAEEEAKRKAEESEKKAAEA
                     KQKVDAEEYALEAKIAELEYEVQRLEKELKEIDESDSEDYLKEGLRAPLQSKLDTKKA
                     KLSKLEELSDKIDELDAEIAKLEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAE
                     ADLKKAVDEPETPAPAPQPAPEKPAEKPAPAPAPEKPAPAPEKPAEKPAPAPAPEKPA
                     PTPETPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWY
                     YLNSNGAMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGS
                     WYYLNSNGAMVTGWLQNNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKV
                     SDKWYYVNGSGALAVNTTVDSYRVNANGEWVN"
     gene            complement(23644..24624)
                     /gene="dusB"
                     /locus_tag="VYP30_000160"
     CDS             complement(23644..24624)
                     /gene="dusB"
                     /locus_tag="VYP30_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1807223.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(24611..25483)
                     /gene="hslO"
                     /locus_tag="VYP30_000161"
     CDS             complement(24611..25483)
                     /gene="hslO"
                     /locus_tag="VYP30_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1807224.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            25648..27075
                     /locus_tag="VYP30_000162"
     CDS             25648..27075
                     /locus_tag="VYP30_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1807225.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPTFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QPPVYYLKNDLDMEDLAGIRQLLFT"
     gene            27234..28742
                     /gene="glpK"
                     /locus_tag="VYP30_000163"
     CDS             27234..28742
                     /gene="glpK"
                     /locus_tag="VYP30_000163"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1807226.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            28784..30610
                     /gene="glpO"
                     /locus_tag="VYP30_000164"
     CDS             28784..30610
                     /gene="glpO"
                     /locus_tag="VYP30_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1807227.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            30680..31384
                     /locus_tag="VYP30_000165"
     CDS             30680..31384
                     /locus_tag="VYP30_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1807228.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            31575..31778
                     /locus_tag="VYP30_000166"
     CDS             31575..31778
                     /locus_tag="VYP30_000166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807229.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(31865..32473)
                     /locus_tag="VYP30_000167"
     CDS             complement(31865..32473)
                     /locus_tag="VYP30_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807230.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            33564..34840
                     /gene="ltrA"
                     /locus_tag="VYP30_000168"
                     /pseudo
     CDS             33564..34840
                     /gene="ltrA"
                     /locus_tag="VYP30_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            35296..36474
                     /locus_tag="VYP30_000169"
     CDS             35296..36474
                     /locus_tag="VYP30_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1807231.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            36788..36919
                     /locus_tag="VYP30_000170"
     CDS             36788..36919
                     /locus_tag="VYP30_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1807232.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            36940..38490
                     /gene="dltA"
                     /locus_tag="VYP30_000171"
     CDS             36940..38490
                     /gene="dltA"
                     /locus_tag="VYP30_000171"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1807233.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPMVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            38487..39731
                     /gene="dltB"
                     /locus_tag="VYP30_000172"
     CDS             38487..39731
                     /gene="dltB"
                     /locus_tag="VYP30_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1807234.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQFLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            39745..39984
                     /gene="dltC"
                     /locus_tag="VYP30_000173"
     CDS             39745..39984
                     /gene="dltC"
                     /locus_tag="VYP30_000173"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1807235.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            39977..41245
                     /gene="dltD"
                     /locus_tag="VYP30_000174"
     CDS             39977..41245
                     /gene="dltD"
                     /locus_tag="VYP30_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1807236.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            41400..41840
                     /gene="adcR"
                     /locus_tag="VYP30_000175"
     CDS             41400..41840
                     /gene="adcR"
                     /locus_tag="VYP30_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1807237.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            41840..42544
                     /locus_tag="VYP30_000176"
     CDS             41840..42544
                     /locus_tag="VYP30_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1807238.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            42537..43343
                     /locus_tag="VYP30_000177"
     CDS             42537..43343
                     /locus_tag="VYP30_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1807239.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            43353..44858
                     /gene="adcA"
                     /locus_tag="VYP30_000178"
     CDS             43353..44858
                     /gene="adcA"
                     /locus_tag="VYP30_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1807240.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(46029..46802)
                     /locus_tag="VYP30_000179"
     CDS             complement(46029..46802)
                     /locus_tag="VYP30_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1807241.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            46978..48381
                     /locus_tag="VYP30_000180"
     CDS             46978..48381
                     /locus_tag="VYP30_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1807242.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLVDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            48496..49134
                     /locus_tag="VYP30_000181"
     CDS             48496..49134
                     /locus_tag="VYP30_000181"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1807243.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            49146..49586
                     /locus_tag="VYP30_000182"
     CDS             49146..49586
                     /locus_tag="VYP30_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1807244.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            49579..50010
                     /locus_tag="VYP30_000183"
     CDS             49579..50010
                     /locus_tag="VYP30_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1807245.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            50001..50471
                     /locus_tag="VYP30_000184"
     CDS             50001..50471
                     /locus_tag="VYP30_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1807246.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            50496..51269
                     /locus_tag="VYP30_000185"
     CDS             50496..51269
                     /locus_tag="VYP30_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1807247.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            51266..52066
                     /locus_tag="VYP30_000186"
     CDS             51266..52066
                     /locus_tag="VYP30_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1807248.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            52125..54419
                     /locus_tag="VYP30_000187"
     CDS             52125..54419
                     /locus_tag="VYP30_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1807249.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            54429..57545
                     /locus_tag="VYP30_000188"
     CDS             54429..57545
                     /locus_tag="VYP30_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1807250.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            57628..59394
                     /locus_tag="VYP30_000189"
     CDS             57628..59394
                     /locus_tag="VYP30_000189"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1807251.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAILGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            59540..60691
                     /locus_tag="VYP30_000190"
     CDS             59540..60691
                     /locus_tag="VYP30_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1807252.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            60836..61720
                     /locus_tag="VYP30_000191"
     CDS             60836..61720
                     /locus_tag="VYP30_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1807253.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            62074..62325
                     /locus_tag="VYP30_000192"
     CDS             62074..62325
                     /locus_tag="VYP30_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1807254.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            62313..62603
                     /locus_tag="VYP30_000193"
     CDS             62313..62603
                     /locus_tag="VYP30_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807255.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQTEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQKLMNKAVKDEVAQI"
     gene            complement(63009..64340)
                     /locus_tag="VYP30_000194"
     CDS             complement(63009..64340)
                     /locus_tag="VYP30_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1807256.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICQDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(64362..65873)
                     /locus_tag="VYP30_000195"
     CDS             complement(64362..65873)
                     /locus_tag="VYP30_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1807257.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(66084..67031)
                     /gene="arcC"
                     /locus_tag="VYP30_000196"
     CDS             complement(66084..67031)
                     /gene="arcC"
                     /locus_tag="VYP30_000196"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1807258.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(67196..68212)
                     /gene="argF"
                     /locus_tag="VYP30_000197"
     CDS             complement(67196..68212)
                     /gene="argF"
                     /locus_tag="VYP30_000197"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1807259.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(68270..69499)
                     /gene="arcA"
                     /locus_tag="VYP30_000198"
     CDS             complement(68270..69499)
                     /gene="arcA"
                     /locus_tag="VYP30_000198"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1807260.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLDVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            70255..71934
                     /locus_tag="VYP30_000199"
     CDS             70255..71934
                     /locus_tag="VYP30_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1807261.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(71974..74058)
                     /locus_tag="VYP30_000200"
     CDS             complement(71974..74058)
                     /locus_tag="VYP30_000200"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1807262.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALQQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGISLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            74230..75510
                     /locus_tag="VYP30_000201"
     CDS             74230..75510
                     /locus_tag="VYP30_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1807263.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            75601..78246
                     /locus_tag="VYP30_000202"
     CDS             75601..78246
                     /locus_tag="VYP30_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1807264.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVATFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSMDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            78330..79199
                     /locus_tag="VYP30_000203"
     CDS             78330..79199
                     /locus_tag="VYP30_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1807265.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLTWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            79193..81073
                     /locus_tag="VYP30_000204"
     CDS             79193..81073
                     /locus_tag="VYP30_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1807266.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVENILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            81451..81813
                     /locus_tag="VYP30_000205"
     CDS             81451..81813
                     /locus_tag="VYP30_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807267.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHTFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(81885..82734)
                     /locus_tag="VYP30_000206"
     CDS             complement(join(81885..82319,82321..82734))
                     /locus_tag="VYP30_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1807268.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDARFKRLVGVQRTTFEEML
                     AVLKTTYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQ
                     WVEATLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIV
                     TSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILADSGYQGPMKIYPQAQTPRKSS
                     KLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIAGII
                     NHELGF"
     gene            complement(82679..82861)
                     /locus_tag="VYP30_000207"
     CDS             complement(82679..82861)
                     /locus_tag="VYP30_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1807269.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
BASE COUNT        25422 a        14842 c        18325 g        24444 t
ORIGIN      
        1 tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt aaagcccttt actgggatgg
       61 tcaaggattt tggctactat ataaacgctt tgagaacgga aaactgactt ggctaagtac
      121 agaaaaggat gtcaaagctc tcgcacctga acaagtagac tggcttatga agggcttttc
      181 tatcactccc caaatatagt ggtttgaaac tagaatagta cacctctgct tctaaaacat
      241 tgttagaaat cgatttgact gtcctgttct tatttcattt tactataaat tcatcagaaa
      301 gtcgtgattt ctattgaaat gaggactttc tttttatact catctgtttt cacaaagcat
      361 tctagtccat ctccgattaa cgatggactt tatcacctcc ttctccagtc cttgtataac
      421 atcttggagt tgattcatga catcttccaa aatttgaaag gctttattct taaatccacg
      481 tttacgaatc tctttccaca cttgttcaat ggggttcatc tctggtgtgt atggaggaat
      541 aaatgcaaag ccaatattag tcggaatctt taaggtactt gatttatgcc atatagcatt
      601 gtccataacg agtaaaagat aatcatctgg ataagcttgt gaaatctcct attcctaaag
      661 cccctttagc gaataacttt ggctcagctt ctattatcgc tcacaccatc catcagaagt
      721 ttaatctgaa ggtacccaat tatcgccaag aagaagattg ggctaggatg ggtttaccaa
      781 tcacacgtaa ggaaatctct aatcggcata tcaagacgag tcaatactat ttggagcccc
      841 tttataacct cttgcgagag agactattga ctcagccctt acttcatgcg gatgaaactt
      901 cttatagggt gctagagagt gatagtcagc tgacttacta ttggactttt ttgtctggga
      961 aagctgagaa acaagggatt acgctttacc atcatgtcgt aatcgatttg ttcatatctt
     1021 atttcaatcc attataaata gtgagaaata tctatcctat cttctagaat gtcttctaaa
     1081 cgtggaaact ctcgtaaaca aagaggtttt agaggcctat ttaccatgga ctaaagttgt
     1141 acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct
     1201 ggagattttt caatagactt cgttattgga cggttacaat tcataaagtg ctgtagagag
     1261 ataacgttca ccgttatctg gtgctagggc aaggactttt ttacctgtac ctaatttttt
     1321 ggcaacctcg atggctccgt agatagctgc agctgaggaa atccctacaa ggaagccttc
     1381 ttttccacca atttcacgtc cgagtgcaag agcgtcatct gatgttacac gaacgatacc
     1441 atcataggct ttagtatcaa gtgtatcagg aataaatcca gctgagatac cttgaatttt
     1501 gtgaggacca ggtttttcac cagatagaat agcagattca tctgcttcta ctgcaaaaac
     1561 ttgaatgtta gaattttctg atttgagtgc atgagaaaca ccagaaatcg ttccaccagt
     1621 acctactcca gcaacaaagg catctaatcc atctttaccg aaagcagcta gtatctcagc
     1681 tcctgttgtt ctttcgtgta cttctggatt agctggattg tcaaattgaa gaggaaggaa
     1741 accatcacgt tcagcagcga tttcttgagc cttagcaata gcacctttca ttccctcgct
     1801 accaggagtt aggacgagtt cagcaccata agcttggata attttacgtc gttctacact
     1861 catagtttca ggcataacga tgacgacttt atacccttta gcagcaccta cccatgaaag
     1921 tccaataccg gtgtttccac ttgttgcttc aacaatagta gaaccaagtt tcagaatacc
     1981 atcttgttca gctttttcaa tcatgctaag ggcaatacgg tcttttacag atgaaccagg
     2041 attaaatgct tcaagcttta tatagacgtc tgcagcacct tctggcacga tgttgttaag
     2101 tttaacaatc ggtgtttgac cgattaattc agtaatgttg ttataaatag acatatgaat
     2161 acctctttgt ataagatatc tttagtataa cgctatccat accatttgta aaatatagaa
     2221 atcctatcga agcgatagga tttctatata tcatagatca aagtcattaa ttttcaagtg
     2281 attgcgttca gttaattcta gtaaataggt gtgaaggaaa acgatatcag gtttcgtttg
     2341 aattgcttca ttttctagta tattttggta cgcatctttt tattttgctc gctaaagtag
     2401 ttgtgagaat gtcaacgaaa cgctgtatta ttcattgttt acactaagtt tacaggaact
     2461 tcaacctctc gtaaaccttg gtcagttaaa gtgacttttc cattaaaaaa ctccacaagt
     2521 gcagctttaa tagtttcttt ttcttcttta tcaacataaa tcatcgtatc gacttgatct
     2581 gtaaagtttg tatccagctc catgagatca tgttctttaa ggaagttact gtactcttgg
     2641 tactgagcat aagacatttg aatagcaatg ccagcctgtt cttttatttc aataatacca
     2701 atttctttga cagctaaggc gacactgccg gcgtaagcac gaattagtcc tccagcgcct
     2761 agtttaatac caccaaagta gcgtgtcacg accacacaga cattggtgag attgtgattt
     2821 tctagtaccc caagcatggg aacaccagca gtaccactag gctcaccatc atcacttgta
     2881 cgtttaattt cactacgttc tccaataata aaggcagagc agttatgtgt cgctttgtag
     2941 tgttcttttt tgatggcagt aatgaagtca cgagcctctt cttcgctata aacacgcttg
     3001 gcatggcaga taaagcgaga ttttttgatt tcttcttgga cttggccgtc ctctttaatt
     3061 gtcctaaatt ccatgattta attgtactaa aaaatcatct aaagtgctag tttttacgaa
     3121 taaagaagta tgaaagtaaa tttagattat ctcggtcgtt tatttactga gaatgaatta
     3181 acagaagaag aacgtcagtt ggcggagaaa cttccagcaa tgagaaagga gaaggggaaa
     3241 cttttctgtc aacgttgtaa tagcactatt ctagaagaat ggtatttgcc catcggtgct
     3301 tactattgtc gagagtgctt gctgatgaag cgagtcagaa gtgatcaaac tttatactat
     3361 tttccgcagg aggattttcc gaagcaagat gttctcaaat ggcgcggcca attaactcct
     3421 tttcaagaga aggtgtcaga gggactgctt caagcagtag acaagcaaaa gccaacctta
     3481 gttcatgcgg taacaggagc tggaaagaca gaaatgattt atcaagtagt ggctaaagtg
     3541 atcaatgcgg gtggtgcagt gtgtttggct agtcctcgca tagatgtttg tttggagctg
     3601 tacaagcgcc tgcaacagga tttttcttgc gggatagctt tgctacatgg agaatcggaa
     3661 ccttattttc gaacaccact agttgttgca acaacccatc agttattgaa gttttatcaa
     3721 gcttttgatt tgctgatagt ggatgaagta gatgcttttc cttatgttga taatcccacg
     3781 ctttaccatg ctgtcaagaa tagtgtaaag gagaatggat tgagaatctt tttaacagcg
     3841 acttcgacca atgagttaga taaaaaggtc cgtttaggag aactaaaaag actgaattta
     3901 ccgagacggt ttcatggaaa tccgttgatt attccaaaac caatttggtt atcggatttt
     3961 aatcgctact tagacaagaa tcgtttgtca ccaaagttaa agtcctatat tgagaagcag
     4021 agaaagacag cttatccgtt actcattttt gcttcagaaa ttaagaaagg ggagcagtta
     4081 gcagaaatct tacaggagca atttccaaat gagaaaattg gctttgtatc ttctgtaaca
     4141 gaggatcgat tagagcaagt acaagctttt cgagatggag aactgacaat acttatcagt
     4201 acgacaatct tggagcgtgg agttaccttc ccttgtgtgg atgttttcgt agtagaggcc
     4261 aatcatcgtt tgtttaccaa gtctagtttg attcagattg gtggacgagt tggacgaagc
     4321 atggatagac cgacaggaga tttgcttttc ttccatgatg ggttaaatgc ttcaatcaag
     4381 aaggcgatta aggaaattca gatgatgaat aaggaggctg gtctatgaag tgcttgttat
     4441 gtgggcagac tatgaagact gttttaactt ttagtagtct cttacttctg aggaatgatg
     4501 actcttgtct ttgttcagac tgtgattcta cttttgaaag aattggggaa gagaactgtc
     4561 caaattgtat gaaaacagag ttgtcaacaa agtgtcaaga ttgtcaactt tggtgtaaag
     4621 aaggagttga agtcagtcat agagcgattt ttacttacaa tcaagctatg aaggattttt
     4681 tcagtcggta taagtttgat ggagacttcc tgttaagaaa agttttcgct tcatttttaa
     4741 gtgaggagtt gaaaaagtac aaagagtatc aatttgttgt aattccccta agtcctgata
     4801 gatatgctaa tagaggattt aatcaggttg agggcttggt agaggcagca ggctttgagt
     4861 atctggattt attagagaaa agagaagaga gagccagttc ttctaaaaat cgttcagagc
     4921 gcttggggac agaacttcct ttctttatta aaagtggagt cactattcct aaaaaaatcc
     4981 tacttataga tgatatctat actacaggag caactataaa tcgtgttaag aaactgttgg
     5041 aagaagctgg tgctaaggat gtaaaaacat tttcccttgt aagatgagga aaaaatttgc
     5101 aaaaatagaa tgaaagcgtt ataataaaat cataaaaaca aaaatgttta gaaagaaggt
     5161 actcatatga ttaaatatag tatccgtggt gaaaacctag aagtaacaga agcaattcgt
     5221 gattatgtag tttctaaact cgaaaagatc gaaaagtact tccaaccaga acaagagttg
     5281 gatgcccgaa ttaacttaaa agtttatcgt gaaaaaacgg ctaaagtgga agtaacgatt
     5341 ccgcttggat ctattactct ccgcgcagaa gatgtatctc aagatatgta tggttcaatt
     5401 gaccttgtaa ctgataaaat tgaacgtcag attcgtaaaa ataaaacaaa aatcgagcgt
     5461 aaaaataaaa ataaggtagc aactggtcaa ttatttacag atgctttggt ggaagattca
     5521 aatattgtcc agtctaaagt tgttcgttca aaacaaattg atttaaaacc aatggatttg
     5581 gaagaagcaa ttctacaaat ggatttattg gggcatgatt tctttatcta tgtggatgtt
     5641 gaagatcaga caaccaatgt gatttatcgt cgtgaggatg gcgaaattgg tttgttagag
     5701 gttaaagaat cttaatttca atatgtgtaa aggtaggttt actgaattgt aaactacctt
     5761 tttcttataa ttgatagaat tactgattac acttttaaaa agtcgctttt tgaggggtat
     5821 tatggtataa tgggtgccaa gaggttttga atgaaaaaat tttatgtaag tccaattttt
     5881 cctattctag taggattgat tgcgtttgga gtcttatcca ctttcattat ttttgttaat
     5941 aataatctgt tgacggtttt aattttgttt ctttttgtag gaggctatgt ttttttattt
     6001 aagaaactga gagtgcatta tacaaggagt gatgtagaac agatacagta tgtaaaccac
     6061 caagcggaag aaagtttgac agctctattg gaacagatgc ctgtaggtgt tatgaaattg
     6121 aatttatctt ctggagaggt tgagtggttt aatccctatg ctgaattgat tttgaccaag
     6181 gaagatggtg attttgattt agaagctgtt caaacgatta ttaaggcttc agtaggaaat
     6241 ccgtctactt atgccaagct tggtgagaag cgttatgctg ttcatatgga tgcttcttcc
     6301 ggtgttttgt attttgtaga tgtatccagg gaacaagcca taacagatga attggtaaca
     6361 agtcgaccag tgattgggat tgtctctgtg gataattatg atgatttgga ggatgcaact
     6421 tctgagtcag atattagtca aatcaatagt tttgtagcta attttatatc agagttttca
     6481 gaaaaataca tgatgttttc tcgtcgggta agtatggatc gattttatct atttactgac
     6541 tacacggtgc ttgagggctt gatgaatgat aaattttctg ttattgatgc tttcagagaa
     6601 gagtcgaaac agagacagtt gcccttgacc ttaagtatgg gattttctta tggcgatgga
     6661 aatcatgatg agatagggaa agttgctttg ctcaatttga acttggctga agtacgtggt
     6721 ggcgaccagg tggttgttaa ggaaaacaac gaaacgaaaa atccagttta ttttggtggt
     6781 gggtctgctg cttcaatcaa gcgtacacgg actcgtacgc gcgctatgat gacagctatt
     6841 tcagataaga ttcggagtgt agatcaggtt tttgtagtcg gtcacaaaag tttagacatg
     6901 gatgctttgg gctctgctgt aggtatgcag ttgttcgcca gcaatgtgat tgaaaatagc
     6961 tatgctcttt atgatgaaga acaaatgtct ccagatattg aacgagctgt ttcattcata
     7021 gaaaaagaag gagttacgaa gttgttgtct gttaaggatg caatggggat ggtgaccaat
     7081 cgttctttgt tgattcttgt agaccattca aagacagcct taacattatc aaaagaattt
     7141 tatgatttat ttacccaaac cattgttatt gaccaccata gaagggatca ggattttcca
     7201 gataatgcgg tcattactta tatcgaaagt ggtgcaagta gtgccagtga gttggtaacg
     7261 gaattgattc agttccagaa ttctaagaaa aatcgtttga gtcgtatgca agcaagtgtt
     7321 ttgatggctg gtatgatgtt ggatactaaa aatttcacct cgcgagtaac tagtcggaca
     7381 tttgatgttg ctagctatct cagaacgcgc ggaagtgata gtattgctat ccaggaaatc
     7441 gctgcgacag attttgaaga atatcgtgag gtcaatgaac ttattttaca ggggcgtaaa
     7501 ttaggttcag atgtactaat agcagaggct aaggacacga aatgctatga tacagttgtt
     7561 attagtaagg cagcagatgc catgttagcc atgtcaggta ttgaagcgag ttttgttctt
     7621 gcgaagaata cacaaggatt tatctctatc tcagctcgaa gtcgtagtaa actgaatgta
     7681 caacggatta tggaagagtt aggcggtgga ggccacttta atttggcagc agctcaaatt
     7741 aaagatgtaa ccttgtcaga agcaggtgaa aaactgacag aaattgtatt aaatgaaata
     7801 aaggaaaagg agaaagaaga atgaaagtaa tctttttagc agatgttaaa ggaaaaggta
     7861 aaaaaggcga aattaaggaa gtaccaacag ggtatgcgca aaactttctt atcaaaaaga
     7921 atctagccaa agaagcgact gctcaagctg taggtgaact tcgtggtaaa caaaaatcgg
     7981 aagaaaaagc tcacgctgag atgattgcag aaggaaaagc aattaaagca caacttgaag
     8041 cagaagaaac tgttgtagaa tttgttgaaa aagttggtcc agatggtcgt acctttggtt
     8101 ctattaccaa taagaagatt gcagaagaat tgcaaaagca atttggaatt aagattgata
     8161 aacgtcatat tcaagtacaa gctccgattc gagcggttgg tttgattgat gtgccagtga
     8221 aaatctatca agatatcaca agtgtaatca atcttcgtgt gaaagaagga taagtttaca
     8281 ctttcttgac aagattgtaa aaggaaggga agtctgatgg cagaagtaga agagttacga
     8341 gtacaacctc aagatatctt agctgagcaa tccgttttag gggctatctt tattgatgag
     8401 agtaaacttg tttttgtgcg agaatacatt gagtctcggg acttttttaa gtatgcccat
     8461 cgtttgattt tccaagccat ggtcgattta tccgatcgtg gtgatgccat agatgcaaca
     8521 acggttcgta ctatccttga taatcaaggt gatttgcaga atattggtgg cttgtcttac
     8581 ttggttgaga ttgtcaattc tgtgccaact tctgctaatg cggagtatta tgctaagatt
     8641 gttgcagaaa aagcaatgct acgtcgttta attgccaagt tgacagagtc tgtcaaccaa
     8701 gcttacgaag cgtcacaacc agctgatgaa attattgctc aggcagaaaa agggttgatt
     8761 gatgtcagtg aaaatgcaaa tcgaagcggg tttaagaaca ttcgagatgt gttgaatctc
     8821 aactttggaa atctggaagc tcgctcgcaa caaacgaccg atattacagg tattgcgaca
     8881 ggttatcgtg atttggatca tatgacaaca ggacttcatg aggaggagtt gattatctta
     8941 gcagctcgtc cagcagttgg taagacagca tttgccttga atatcgctca gaacattggg
     9001 actaagttgg acaaaacggt tgctattttt tcactcgaaa tgggtgcgga aagcttggta
     9061 gatcgtatgt tagctgcaga aggcttagtg gagtcacatt ctatccgtac agggcaattg
     9121 acagatgagg agtggcaaaa atatactatt gctcagggta atctagctaa cgccagtatc
     9181 tatatcgatg atacgccagg tattcggatt acagagattc gttctcgttc tcgtaaattg
     9241 gctcaagaaa ctggaaatct tggtttgatt ttgatagact atttgcaact tatcacggga
     9301 actggtcgag aaaatcgtca acaagaagtt tctgaaattt ctcgtcagtt gaaaatacta
     9361 gccaaggaat tgaaggttcc agtaatcgct ctgagtcagc tttctcgtgg tgtagaacaa
     9421 cgtcaggaca agagaccggt cttgtctgat attcgtgaat ctgggtctat tgagcaggac
     9481 gctgatatcg tagcttttct ctatcgcgat gactactatg aacgtggtgg tgaagaagag
     9541 gagggtatcc caaataataa ggtggaagtt attatcgaga aaaaccgtag tggagctcgt
     9601 ggaacagtgg aattgatttt ccaaaaagaa tacaataaat tttcaagtat ctcaaagagg
     9661 gaggcataag atgtcagatg catttacaga tgtagccaag atgaaaaaaa tcaaagaaga
     9721 aatcaaggca catgagggac aagtcgtaga aatgactttg gagaatggtc gtaagcgcca
     9781 aaaaaataga ttgggtaagc taattgaagt ttatccatct ctatttattg tggagtttgg
     9841 ggatgtggaa ggagataaac aagttaatgt ttacgttgaa tcctttactt actcagatat
     9901 tcttacagaa aagaatttga ttcattatct tgactaaagt gagaaatttt ctcacttttt
     9961 cttttttctc cgaataattt aggtgaaggc aatcatcgct ttatattatt tttcaaggag
    10021 gaagaatgaa aattttaccg tttatagcaa gaggaacaag ttattacttg aagatgtcag
    10081 ttaaaaagct tgttcctttt ttagtagtag gattgatgct agcagctggt gatagtgtct
    10141 atgcctattc cagaggaaat ggatcgattg cgcgtgggga tgattatcct gcttattata
    10201 aaaatgggag ccaggagatt gatcagtggc gcatgtattc tcgtcagtgt acttcttttg
    10261 tagcctttcg tttgagtaat gtcaatggtt ttgaaatgcc ggcagcttat ggaaatgcga
    10321 atgaatgggg acatcgtgct cgtcgggaag gttatcgtgt agataataca ccgacgattg
    10381 gttccattac ttggtctact gcaggaactt atggtcatgt tgcctgggtg tcaaatgtaa
    10441 tgggagatca gattgagatt gaggaatata actatggtta tacagaatcc tataataaac
    10501 gagttgtaaa agcaaacacg atgacaggat ttattcattt taaagatttg gatggtggca
    10561 gtgttgggaa tagtcaatcc tcagcttcaa caggcggaac tcattatttt aagaccaagt
    10621 ctgctattaa aactgaacct ctagctagcg gaactgtgat tgattactat tatcctggag
    10681 agaaggttca ttatgatcag atacttgaaa aagacggcta taagtggttg agttatactg
    10741 cctataatgg aagttatcgt tatgttcaat tggaggctgt gaataaaaat cctctaggtc
    10801 attctgttct ttcttcaaca ggaggaactc attattttaa gaccaagtct gctattaaaa
    10861 ctgaacccct agttagtgca actgtgattg attactatta tcctggggag aaggttcatt
    10921 atgatcagat acttgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa
    10981 gtcgtcgcta tatacagcta gagggagtga cttcttcaca aaattatcag aatcaatcag
    11041 gaaatatctc tagctatgga tccaataata gttcaactgt cggttggaag aaaataaatg
    11101 gtagttggta tcatttcaaa tcaaatggtt ctaaatcaac aggatggctg aaagatggtt
    11161 ctagctggta ttatttgaaa ttatctggtg aaatgcagac aggatggtta aaggagaatg
    11221 gctcgtggta ttatctgggt agttcagggg caatgaaaac aggctggtac caggtctctg
    11281 gtaagtggta ttattcttac tcttcaggcg ccttagctgt taatacgacg gtggatggct
    11341 acagagtaaa cagtgatgga gaacgagtat agaaaattgg agtaggagaa atttcctgct
    11401 cttttctgta agcagtttcc ttgacatttt ttttattttg cgctatcata tatacatata
    11461 atatatggga gtctgtgtac agtctgagag gaagtgttaa acttcgaccg cacctgatct
    11521 gggtaatgcc agcggaggga acgatactta gtctaatttt gcaccttttc catgtatggt
    11581 aaaggttttt ctttttttaa aaaggaaaac gagaagagga ggttcttatg aaagcaagca
    11641 ttgccttgca agttttaccc ctagcacagg ggattgatcg gatagctgtt attgatcagg
    11701 tcattgctta tctgcaaact caagaagtga cgatggtagt gacaccattt gaaacggtct
    11761 tggaagggga gtttgatgag cttatgcgca ttctaaaaga agcgctggaa gtggcagggc
    11821 aggaggcaga caatgtcttt gccaatgtca aaataaatgt aggagagatt ttaagtattg
    11881 atgagaaact tgagaagtat actgagacga cacattagtc tattgggctt tctcggagtc
    11941 ttgttaatct ggcagttagc aggttttctt aaacttctcc ccaagtttat cctgccgaca
    12001 cctcttgaaa ttctccagcc ctttgttcgt gacagagaat ttctctggca ccatagctgg
    12061 gcgaccttga gagtggcttt actggggctg attttgggag ttttgattgc ctgtcttatg
    12121 gctgtgctca tggatagttt gacttggctc aatgacctga tttaccctat gatggtggtc
    12181 attcagacca ttccgaccat tgccatagct cctatcctgg tcttgtggct aggttatggg
    12241 attttgccca agattgtctt gattatctta acgacaacct ttcccatcat cgttagtatt
    12301 ttggacggtt ttaggcattg cgacaaggat atgctgacct tgtttagtct gatgcgggcc
    12361 aagccttggc aaatcctgtg gcattttaaa atcccagtta gcctgcctta cttttatgca
    12421 ggtctgaggg tcagtgtctc ctacgccttt atcacaactg tggtatctga gtggttggga
    12481 ggttttgaag gtcttggtgt ttatatgatt cagtctaaaa aattgtttca gtatgatacc
    12541 atgtttgcca ttattattct ggtgtcgatt atcagtcttt tgggtatgaa gctggtcgat
    12601 atcagtgaaa aatatgtgat taaatggaaa cgttcgtaga attagaatgt ttctgaaaaa
    12661 gaaaagagga aatcaaaatg aagaaaacat ggaaagtgtt tttaacgctt gtaacagctc
    12721 ttgtagctgt tgtgcttgtg gcctgtggtc aaggaactgc ttctaaagac aacaaagagg
    12781 cagaacttaa gaaggttgac tttatcctag actggacacc aaataccaac cacacagggc
    12841 tttatgttgc caaggaaaaa ggttatttca aagaagctgg agtggatgtt gatttgaaat
    12901 tgccaccaga agaaagttct tctgacttgg ttatcaacgg aaaggcacca tttgcagtgt
    12961 atttccaaga ctacatggct aagaaattgg aaaaaggagc aggaatcact gccgttgcag
    13021 ctattgttga acacaataca tcaggaatca tctctcgtaa atctgataat gtaagcagtc
    13081 caaaagactt ggttggtaag aaatatggga catggaatga cccaactgaa cttgctatgt
    13141 tgaaaacctt ggtagaatct caaggtggag actttgagaa ggttgaaaaa gtaccaaata
    13201 acgactcaaa ctcaatcaca ccgattgcca atggcgtctt tgatactgct tggatttact
    13261 acggttggga tggtatcctt gctaaatctc aaggtgtaga tgctaacttc atgtacttga
    13321 aagactatgt caaggagttt gactactatt caccagttat catcgcaaac aacgactatc
    13381 tgaaagataa caaagaagaa gctcgcaaag tcatccaagc catcaaaaaa ggctaccaat
    13441 atgccatgga acatccagaa gaagctgcag atattctcat caagaatgca cctgaactca
    13501 aggaaaaacg tgactttgtc atcgaatctc aaaaatactt gtcaaaagaa tacgcaagcg
    13561 acaaggaaaa atggggtcaa tttgacgcag ctcgctggaa tgctttctac aaatgggata
    13621 aagaaaatgg tatccttaaa gaagacttga cagacaaagg cttcaccaac gaatttgtga
    13681 aataatgaca gaaattagac tagagcacgt cagttatgcc tatggtcagg agaggatttt
    13741 agaggatatc aacctacagg tgacttcagg cgaagtggtt tccatcctag gcccaagtgg
    13801 tgttggaaag accaccctct ttaatctaat cgctgggatt ttagaagttc agtcagggag
    13861 aattgtcctt gatggtgaag aaaatcccaa ggggcgcgtg agttatatgt tgcaaaagga
    13921 tctgctcttg gagcacaaga cggtgcttgg aaatatcatt ctgcccctct tgattcaaaa
    13981 ggtggataag gcagaagcta tttcccgagc ggataaaatt cttgcgacct tccagctgac
    14041 agctgtaaga gacaagtatc ctcatgaact tagcggtggg atgcgccagc gtgtagcctt
    14101 actccggacc tacctttttg ggcacaagct ctttctctta gatgaggcct ttagcgcctt
    14161 ggatgagatg acaaagatgg aactccacgc ttggtatctt gagattcaca aacagttgca
    14221 gctaacaact ctgatcatca cgcatagtat tgaggaggcc ctcaatctca gcgaccgcat
    14281 ctatatcttg aaaaatcgcc ctgggcagat tgtttcagaa attaaactag attggtctga
    14341 agatgaggac aaggaagtcc aaaagattgc ctacaaacgt caaatcttgg cagaattagg
    14401 cttagataag tagaaaaata gggagttggt gaagattatc ctttaccagc gccctttttc
    14461 ttttaaaaat gagaaaattt cggtataata gtcaaacaag gtcaaggttt aaagagagag
    14521 gtgggtttgt tatgagattt aaaaatacat cggatcatat tgaggcctac atcaaggcga
    14581 ttttagatca atctggtatc gtggagttgc aacggagtca gttggcagat acctttcagg
    14641 ttgttcctag tcagattaac tacgtgatca agacacgctt tacggaaagt agaggctact
    14701 tggttgaaag taagcgtggt ggcggaggct acattcgtat aggacggatt gagttttcta
    14761 gtcatcatga aatgctccgg gatctgcttt actcgattgg tgagcgagtc agtcaagaaa
    14821 tttatgagga tattctccag cttttggttg agcaggaatt gatgaccaag caggagatga
    14881 atttgctaga atcagtagct ttggatcgcg ttttaggaga agaagctcca gttgttcgag
    14941 caaacatgct acgtcaggtc atacaagagg tagatagaaa agggaagtaa gatgaactat
    15001 tcaaaagcat tgaatgaatg tatcgaaagt gcctacatgg ttgctggaca ttttggagct
    15061 cgttatctag agtcgtggca cttgttgatt gccatgtcta atcacagtta tagtgtagca
    15121 ggggcaactt taaatgatta tccgtatgag atggaccgtt tagaagaggt ggctttggaa
    15181 ctgactgaaa cggactatag ccaggatgaa acctttacgg aattgccgtt ctcccgtcgt
    15241 ttgcaggttc tttttgatga agcagagtat gtagcgtcag tggtccatgc taaggtacta
    15301 gggacagagc acgtcctcta tgcgattttg catgatggca atgccttggc gactcgtatc
    15361 ttggagaggg ctggtttttc ttatgaagac aagaaagatc aggtcaagat tgctgccctt
    15421 cgtcgaaatt tagaagaacg tgcaggctgg actcgtgaag atctcaaggc tttacgccaa
    15481 cgccatcgta cagtagctga caagcaaaat tctatggcca atatgatggg catgccgcag
    15541 actcctagtg gtggtctcga ggactatacg catgatttga cagagcaagc gcgttctggc
    15601 aagttagaac cagtcatcgg tcgggacaag gaaatctcac gtatgattca aatattgagc
    15661 cgtaagacta agaacaaccc tgtcttggtt ggggatgctg gtgtcgggaa aacagctctg
    15721 gcccttggtc ttgctcagcg tattgctagt ggtgacgtgc ctgcggaaat ggctaagatg
    15781 cgcgtgttag aacttgattt gatgaatgtc gttgcaggga cacgcttccg tggtgacttt
    15841 gaagaacgca tgaataatat catcaaggat attgaagaag atggccaagt catcctcttt
    15901 atcgatgaac tccacaccat catgggttct ggtagcggga ttgattcgac tctggatgcg
    15961 gccaatatct tgaaaccagc cttggcgcgt ggaactttga gaacggttgg tgccaccact
    16021 caggaagaat atcaaaaaca tatcgaaaaa gatgcggctc tttctcgtcg tttcgctaaa
    16081 gtgacgattg aagaaccaag tgtggcagat agtatgacta ttttacaagg tttgaaggcg
    16141 acttatgaga aacatcaccg tgtacaaatc acagatgaag cggttgaaac agcggttaag
    16201 atggctcatc gttatttaac cagtcgtcac ttgccagact ctgctatcga cctcttggac
    16261 gaagcagcag caacagtgca aaataaggca aagcatgtaa aagcagacga ttcagatttg
    16321 agtccagctg acaaggccct gatggatggc aagtggaaac aggcagccca gctaatcgca
    16381 aaagaagagg aagtacctgt ctacaaagac ttggtgacag agtctgatat tttgaccacc
    16441 ttgagtcgct tgtcaggaat cccagttcaa aaactgactc aaacggatgc taagaagtat
    16501 ttaaatcttg aagcagaact ccataaacgt gtcatcggtc aagatcaagc tgtttcaagt
    16561 attagtcgtg cgattcgccg taatcagtca ggaattcgca gtcacaagcg tccgatcggt
    16621 tcctttatgt tcctaggacc cacaggtgtc ggtaagaccg agttggccaa ggctttggca
    16681 gaagttctct ttgatgacga atcagccctt atccgctttg atatgagtga gtatatggag
    16741 aaattcgcag ccagccgtct aaatggagct cctccaggct atgtgggtta cgaagaaggt
    16801 ggggagttga cagagaaggt tcgcaataaa ccctattccg ttctcctctt tgatgaggta
    16861 gagaaggctc acccagatat ctttaatgtt ctcttgcagg ttctggatga cggtgtcttg
    16921 acagatagca agggacgcaa ggtcgatttt tcaaatacca ttatcattat gacatcgaat
    16981 ctaggtgcga ctgcccttcg tgatgataag actgttggtt ttggggctaa ggatattcgt
    17041 tttgaccagg aaaatatgga aaaacgcatg tttgaagaac tgaaaaaagc ttatagaccg
    17101 gaattcatca accgtattga tgagaaggtg gtcttccata gcctatctag tgaccatatg
    17161 caggaagtgg tgaagattat ggtcaagcct ttagtggcaa gtttggctga aaaaggcatt
    17221 gacttgaaat tacaagcttc agctctgaaa ttgttagcaa atcaaggata tgacccagag
    17281 atgggagctc gcccacttcg cagaaccctg caaacagaag tggaggacaa gttggcagaa
    17341 cttcttctta agggagattt agtggcaggc agcacactta agattggtgt caaagcaggc
    17401 cagttaaaat ttgatattgc ataaaagaat aaaagtatca gcatctgacc ataagtcaca
    17461 gtggagtgaa actcaatgaa aatcaaagag caaactaggc agctagccgc aggttgctta
    17521 aaacactgtt ttgaggttgc agatagagct gacgtggttt gaagagattt tcgaagagta
    17581 tgaaactaaa acctatagct tctaaacgat tcgtggtttt caccattcaa cacaaaattc
    17641 atatgtttat taccctccgt cgtatttgtc ttagagcgtg tgtagtagaa aaagagcagt
    17701 cttatctgaa atttttattc tttcaaaaga gacctgtttc ttttttgcat gtcaaatccg
    17761 ttctaactgg tatttgaaaa atcaaactaa tactcaatga aaatcaaaga acaaactagg
    17821 cagctagccg caggttgctc aaaacactgt tttgaggttg tagatagagc tgacgtggtt
    17881 tggagagatt ttcgaagagt ataagctgca agatgaatga ttttcttgta ttgacgttgt
    17941 tgttgacaaa aagtagcgga taaatgaaat ccattccatt atcatagatg ataggctggt
    18001 aggaaatttt caaatagcat acaggaaata gatgtatgga gttctggtag tagaaaggga
    18061 gagagatgaa cattttagtt gcagatgacg aggaaatgat tagagaagga attgcagcat
    18121 ttctgacaga agagggttat catgtcatta tggctaagga tggacaagag gtcttggaaa
    18181 aatttcaaga tctccctatc catctcatgg tactggattt aatgatgcct aggaagagtg
    18241 gttttgaagt gttaaaagaa atcaatcaaa agcacgatat tcctgtcatc gtcttgagtg
    18301 ctctgggaga tgaaactact cagtcacagg tatttgatct ctatgctgat gatcatgtga
    18361 caaaaccttt ttctttggta ctgcttgtca agcgtattaa ggcgcttatc agacgttact
    18421 acgtcataga ggatatttgg cgatatcagg atgtaacagt ggattttacc tcttacaaag
    18481 cacattataa aaatgaagaa attgatctca aaccaaagga attactggta ctaaagtgtt
    18541 tgattcagca taaaaatcaa gttttaagta gagagcagat attggaagaa atttcaaaag
    18601 atgtagctga tttaccttgt gatagggtcg ttgatgtcta tattcgtact cttcgcaaaa
    18661 aattagcttt agattgtatc gtgactgtga aaaatgttgg gtataagatt agcttatgat
    18721 aaaaaatcct aaattattaa ccaagtcttt tttaagaagt tttgcaattc taggtggtgt
    18781 tggtctagtc attcatatag ctatttattt gacctttcct ttttattata ttcaactgga
    18841 gggggaaaag tttaatgaga gcgcaagagt gtttacggag tatttaaaga ctaagacatc
    18901 tgatgaaata ccaagcttac tccagtctta ttcaaagtcc ttgaccatat ctgctcacct
    18961 taaaagagat attgtagata agcggctccc tcttgtgcat gacttggata ttaaagatgg
    19021 aaagctatca aattatatcg tgatgttaga tatgtctgtt agtacagcag atggtaaaca
    19081 ggtaacagtg caatttgttc acggggtgga tgtctacaaa gaagcaaaga atattttgct
    19141 tttgtatctc ccatatacat ttttggttac aattgctttt tcctttgttt tttcttattt
    19201 ttatactaaa cgcttgctca atcctctttt ttacatttca gaagtgacta gtaaaatgca
    19261 agatttggat gacaatattc gttttgatga aagtaggaaa gatgaagttg gtgaagttgg
    19321 aaaacagatt aatggtatgt atgagcactt gttgaaggtt attcatgagt tggaaagtcg
    19381 taatgagcaa attgtaaaat tgcaaaatca aaaggtttcc tttgtccgtg gagcatcaca
    19441 tgagttgaaa acccctttag ccagtcttag aattatccta gagaatatgc agcataatat
    19501 tggagattac aaagatcatc caaaatatat tgcaaagagt ataaataaga ttgaccagat
    19561 gagccactta ttggaagaag tactggagtc ttctaaattc caagagtgga cagagtgtcg
    19621 tgagaccttg actgttaagc cagttttagt agatatttta tcacgttatc aagaattagc
    19681 tcattcaata ggtgttacaa ttgaaaatca attgacagat gctaccaggg tcgtcatgag
    19741 tcttagggca ttggataagg ttttgacaaa cctgattagt aatgcaatta aatattcaga
    19801 tgaaaatggg cgcgtaatca tatccgagca agatggctat ctctctatca agaatacatg
    19861 tgcgcctcta agtgaccaag aactagaaca tttatttgat atattctatc attctcaaat
    19921 cgtgacagat aaggatgaaa gttccggttt gggtctttac attgtgagta atattttaga
    19981 aagctatcaa atggactata gttttctccc ttatgaacac ggtatggaat ttaagattag
    20041 cttgtagaca gattagtttt ttattaaagt tcacataggg ttaacataag tgtattattc
    20101 tttatataga taaaaatata gataaaagaa aggatactaa tatggtatta gcgattattt
    20161 tagtaacatt ccttattcga ttgatttttt taaagcgttc gatagagaat gagaaacgaa
    20221 tccttagcaa tggcgggaaa gaatttggag ttgagaatac aaaacgatta acgttggctc
    20281 atattgtttt ttatctctct tgcctcgttg aagcaatggt gcataagaca atgtttgatg
    20341 gtatgagcat ggttggttta gtcttgctta ttttttctat gctgatgttg atgttggtga
    20401 ttcacttgtt gggagatatt tggacagtga agcttatgct tgtcaataat cacaaatatg
    20461 tagatcatat cttgtttagg acagtaaaac atcctaatta ctttttaaat attttacctg
    20521 agttgattgg cttgaccttg ttgagtcatg cctatatgac ttttgtttta gtttttccag
    20581 tttatgcagt tattttgtat cgacgaatag ctgaagagga aaagctatta catgaagtta
    20641 taatcccaaa tggaagcata aagagataaa tacaaaattc gatttatata cagttcatat
    20701 tgaagtgata tagtaaggtt aaagaaaaaa tatagaagga aataaacatg tttgcatcaa
    20761 aaagcgaaag aaaagtacat tattcaattc gtaaatttag tattggagta gctagtgtag
    20821 tagttgctag tcttgttatg ggaagtgtgg ttcatgcgac ggagaatgag ggaattaccc
    20881 aagtagccac ttcttataat aaggcaaatg aaagtcagac agaacatagg aaagctgcta
    20941 aacaagtcga tgaagatata aaaaaaatgt tgagtgagat ccaagaatat ataaaaaaaa
    21001 tgttgagtga gatccaatta gataaaagaa aacataccca aaatgtcaac ttaaacagaa
    21061 agttgagcgc aattcaaacg aagtatttgt atgaattaag agttttaaaa gagaagtcga
    21121 aaaaagaaga gttgacgtca aaaacaaaaa aagagttaga cgcagctttt gagaagttta
    21181 aaaaagaacc agaacttact aaaaaattag cagaagctaa acaaaaagcc aaggctcaaa
    21241 aagaagaaga tttccgtaac tacccaacca atacttacaa aacgcttgaa cttgaaattg
    21301 ctgagttcga tgtgaaagtt aaagaagcgg agcttgaact agtaaaagag gaagctaaac
    21361 cccgaaacga ggaaaaaatt aagcaagcaa aagcgaaagt tgagagtaaa aaagctgagg
    21421 ctacaaggtt agaagaaatc aagacagaac gtaaaaaagc agaagaagaa gctaaacgaa
    21481 aagcagaaga atctgagaaa aaagctgctg aagccaaaca aaaagtggat actaaagagc
    21541 aaggtaaacc aaagaggcgg gcaaaacgag gagtttctgg agagctagca acacctgata
    21601 aaaaagaaaa tgatgcgaag tcttcagatt ctagcgtagg tgaagaaact cttccaagcc
    21661 catcccttaa tatggcaaat gaaagtcaga cagaacatag gaaagatgtc gatgaatata
    21721 taaaaaaaat gttgagtgag atccaattag atagaagaaa acatacccaa aatgtcaact
    21781 taaacataaa gttgagcgca attaaaacga agtatttgta tgaattaagt gttttaaaag
    21841 agaactcgaa aaaagaagag ttgacgtcaa aaaccaaagc agagttaacc gcagcttttg
    21901 agcagtttaa aaaagataca ttgaaaccag aaaaaaaggt agcagaagct gagaagaagg
    21961 ttgaagaagc taagaaaaaa gccaaggatc aaaaagaaga agatcgccgt aactacccaa
    22021 ccaatactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtgaaa gttaaaaaag
    22081 cggagcttga actagtaaaa gaggaagcta acgaatctcg aaacgaggaa aaaattaagc
    22141 aagcaaaaga gaaagttgag agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga
    22201 cagatcgtaa aaaagcagaa gaagaagcta aacgaaaagc agaagaatct gagaaaaaag
    22261 ctgctgaagc caaacaaaaa gtggatgctg aagaatatgc tcttgaagct aaaatcgctg
    22321 agttggaata tgaagttcag agactagaaa aagagctcaa agagattgat gagtctgact
    22381 cagaagatta tcttaaagaa ggcctccgtg ctcctcttca atctaaattg gataccaaaa
    22441 aagctaaact atcaaaactt gaagagttga gtgataagat tgatgagtta gacgctgaaa
    22501 ttgcaaaact tgaagttcaa cttaaagatg ctgaaggaaa caataatgta gaagcctact
    22561 ttaaagaagg tttagagaaa actactgctg agaaaaaagc tgaattagaa aaagctgaag
    22621 ctgaccttaa gaaagcagtt gatgagccag aaactccagc tccggctcct caaccagctc
    22681 cagaaaaacc agctgaaaaa ccagctccag ctccagctcc agaaaaacca gctccagctc
    22741 cagaaaaacc agctgaaaaa ccagctccag ctccagctcc agaaaaacca gctccaactc
    22801 cagaaactcc aaaaacaggc tggaaacaag aaaacggtat gtggtacttc tacaatactg
    22861 atggttcaat ggcaacaggc tggctccaaa acaatggctc atggtactac ctcaacagca
    22921 atggcgctat ggcgacaggc tggctccaaa acaatggctc atggtactac ctcaacagca
    22981 atggcgctat ggcgacagga tggctccaat acaatggttc atggtactac ctcaacgcta
    23041 atggtgatat ggcgacagga tggttccaat acaatggttc atggtactac ctcaacgcta
    23101 atggtgatat ggcgacagga tggctccaat acaatggttc atggtactac ctaaacagca
    23161 atggtgctat ggtaacagga tggctccaaa acaatggctc atggtactac ctaaacgcta
    23221 acggttcaat ggcaacagat tgggtgaaag atggagatac ctggtactat cttgaagcat
    23281 caggtgctat gaaagcaagc caatggttca aagtatcaga taaatggtac tatgtcaatg
    23341 gctcaggtgc ccttgcagtc aacacaactg tagatagcta tagagtcaat gccaatggtg
    23401 aatgggtaaa ctaaacttaa tataactagt taatactgac ttcctgtaag aactctttaa
    23461 agtattccct acaaatacca tatcctttca gtagataata tacccttgta ggaagtttag
    23521 attaaaaaat aactctgtaa tctctagccg gatttatagc gctagagact acggagtttt
    23581 tttgatgagg aaagaatggc ggcattcaag agactcttta agagagttac gggttttaaa
    23641 ctattaagcc ttctccaatt gcaagagggc ttcaatctct gctagggtgc tagcttgcga
    23701 aatggctcca cggagtttgg cagcgccaga tgttccacgg aggtagtgag gagcgaggcc
    23761 gcggaattca cgaactgcga cgttttctcc tttgaggtta atcaatcgtt tcaagtgttc
    23821 gtaggcgatc ttcatcttgt cttcaaaggt caaatcaggt aggatttctc ctgtttcaaa
    23881 gtaatggttg atttggttga agaggtaagg atttcccatg gcagctcggc caatcatgac
    23941 tgcgtcagca ccaacttctt cgatgcgttg cttggcttct tggacagtac ggatatcacc
    24001 gttggcgatg aatggaatct tggttagagc ttgggcaacc ttgtaaaggg tctcaaggtc
    24061 tgcgtggcca gtatacattt gttcacgggt acggccatgc atggcgaggg cagaaacacc
    24121 tgcagcttca gcagcgaggg cattttctac tgccagagat gggtccgccc agccggtacg
    24181 cattttgaca gtaagtggga tatcaaggac agactggacc ttgttgatga tagagtagat
    24241 cttgtcagga tccttgagcc acatagcacc agcttcgttc ttcacgattt tgttgacagg
    24301 gcagcccatg ttgatatcga cgatatcggt cttggtgttt tcttggatga attctgctgc
    24361 gcgtgctagg ctgtcttcat cgctaccaaa aagttggata gagacagggt tttcgccctc
    24421 atcgatatga agcatgtgca gggttttttc gttgttgtat tggattccct tgtcagagac
    24481 catttccatt acaacgagtc cagctccgag ctcttttgcg atggtacgaa aggctgagtt
    24541 ggtcacgcca gccataggcg ctaaaacggt acgattggga atctcaacat tgccaatcat
    24601 aaaaggtgta ttaagatttg tcacgaatga gttcctccag gtccttttca tcaaagttgt
    24661 aagtagtttg gcagaattga caagtgattt ctgccccgtg gtcttcctct ttcatttcct
    24721 gtaagtctga gcttggaagg ctggcaagag cgttcataaa gcgttcatgg ctacagtcac
    24781 attggaaacg gatttcttct tcagaaagac gcttgtaggc ttcgtccccg tagatagcct
    24841 tgaggagggc ttcgatatgg tcgtcgcttt cgagaagagt agagatagct ggcatttctt
    24901 ggatgcgttt ttcaaagcga gcaatctctt ctttcttggc tcctggcaag acttgaacta
    24961 ggaaaccacc tgcaaccttg accttgtctt cctcgtccaa aaggacattg aggccgaccg
    25021 ctgaaggcgt ttgttggctt tcagtaaggt aaaaggcaag gtcttcaccg atttctccag
    25081 agatgagggg agttatagag ttgtaaggat ttccagcacc gtagtctgtg ataacgagga
    25141 attgaccatt tccaacaaaa ggtccgacta ggacttcacc agtcgcagtc tttttgatgt
    25201 caacaccagg attttgaaca tagcctttga cgttcccctt ggtatcagcg acggtgataa
    25261 tagcacctag agagctagag cccaacacct taactgtaag tttggtattt cctttttcat
    25321 tggctgcgag aatctggctg gcgataagag ttcgaccaag cgctacagtt gagctagctt
    25381 gggtttgatg tttttcttga gcagtgcgga cggtttccgt gctatcaagg acaaaagcac
    25441 gaaaggctcc gctttctgat atagttttaa taattttatc catagctact attttagcat
    25501 aaaaatgccc aaagggggag ccgtgtgttt actgattttc aggataatgg accaggaaat
    25561 cagcatgaaa ataaaaagag aaacagatta ttttagcatt tgtaagattt atgctatgct
    25621 taaggtagaa aatgaaaggg gtaacaaatg tatttaggag atttgatgga gaaagccgag
    25681 tgtggtcaat tttcaatcct ttcctttcta ttacaagagt ctcagacgac cgtcaaggct
    25741 gtaatggaag aaacaggatt ttcaaaagca accctaacca aatatgtcac cctgctcaat
    25801 gacaaggctt tggatagtgg cttagagctg gctattcact cagaagatga aaatctgcgt
    25861 ctgtctatcg gtgcagctac caaggggaga gatattcgga gcttgttttt ggagagtgct
    25921 gttaaatacc agattttggt ttatcttctc taccaccaac agtttttagc ccatcagctg
    25981 gctcaagaat tggtgattag cgaggctacg cttggtcgtc acttggctgg tttaaatcag
    26041 attttgtcag aatttgattt atccatccaa aatggacgtt ggcgaggtcc agagcatcag
    26101 attcgctatt tctatttctg tcttttccga aaggtctggt cgagtcagga atgggaaggt
    26161 cacatgcaga aaccagagag aaaacaggag attgccaatt tagaggaaat ctgcggtgca
    26221 agtttgtctg tggggcagaa attggacttg gttctctggg ctcacatcag tcaacaacgt
    26281 cttcgggtca atgcttgtca gtttcaagtc atagaagaga aaatgcgagg gtattttgac
    26341 aatattttct accttcgttt gctgagaaag gttccgtcct tttttgctgg gcaacatatt
    26401 ccactaggag ttgaggatgg tgagatgatg atattcttct cttttctcct atctcatcgc
    26461 attcttcctc ttcatactat ggagtatatt cttggttttg gagggcagtt ggcagattta
    26521 ctgacgcaat tgattcaaga aatgaagaag gaggaactat tgggggatta tacagaggac
    26581 catgtcacct atgaactcag tcagctttgt gctcaagtct atctctataa gggctatatt
    26641 ttacaggatc gctacaagta ccagttagag aatcgtcatc catatttact gatggaacat
    26701 gattttaaag agacagcaga ggagattttt catgctctac ctacttttca acaggggaca
    26761 gatttagata agaagattct ctgggaatgg ctccagttaa tcgaatatat ggctgaaaac
    26821 ggtggccagc atatgcggat tggtctggat ttgacatctg gttttcttgt cttttcaagg
    26881 atggcagcca ttttgaaacg gtatttggaa tacaatcgtt ttattaccat tgaagcttat
    26941 gaccctagtc ggcattatga tttgctggtt accaataacc cgattcataa gaaggaacag
    27001 cccccagttt attatttaaa aaatgacttg gatatggaag atttggcagg gattcgtcag
    27061 ttattattca cttaaaaggc ttggttaatc caggtctttt ttgtgaaatt cacacaatct
    27121 cctcacattt ttttaaaaat taaaaaaagt tgataaacaa gaaagcgctt tattttgtat
    27181 actagtaagt gtaaagagga aacacctcaa gatctttatc aggaggacag tacatgtcac
    27241 aagaaaaata catcatggcc attgaccagg gaactacaag ttctcgtgcc atcattttca
    27301 acaaaaaagg ggaaaaggtt agctcgagtc aaaaagagtt tacccagatt ttccctcagg
    27361 caggttgggt tgagcacaat gccaatgaaa tttggaactc tgttcagtca gttattgcgg
    27421 gtgctttcat cgaaagtggt gtcaagccaa atcaaatcga ggcaatcggg attaccaacc
    27481 aacgtgaaac aacggttgtc tgggataaga aaacaggact tcctatctac aatgctatcg
    27541 tttggcagtc acgccagaca gcacctttgg ctgagcaact aaaaagccaa ggttatgtgg
    27601 aaaaattcca tgaaaagact ggtttgatta ttgatgctta cttctctgct accaaggttc
    27661 gttggatttt ggatcatgta gaaggtgctc aagagcgagc agaaaaaggg gaattgctct
    27721 ttggtactat cgatacttgg ttggtttgga aattgactga cggtgcggct cacgtgactg
    27781 actactcaaa tgcagctcgt accatgcttt ataacattaa agaactcaaa tgggatgatg
    27841 agattttgga aatccttaac attccgaagg ctatacttcc agaagttcgt tctaactccg
    27901 aaatctacgg caagacagct ccattccatt tctacggtgg agaggtgcca atctcaggta
    27961 tggctgggga ccaacaagca gccctctttg gacagttggc ttttgagcca ggtatggtta
    28021 agaatactta tggaacaggc tctttcatca tcatgaatac tggggaagag atgcagttgt
    28081 ctgaaaacaa cctcttgaca accattggtt acggaatcaa cggtaaggtt tattatgcct
    28141 tggaaggttc tatcttcatc gcaggaagtg ctattcagtg gcttcgtgac ggtcttcgca
    28201 tggttgaaaa ttcaccagaa tctgaaaaat acgctcgtga ttctcacaac aacgatgaag
    28261 tttatgtcgt tccagccttt acaggtctag gcgctccata ctggaaccaa aatgctcgtg
    28321 gttccgtctt tggtttgact cgtggaacaa gcaaagaaga ctttatcaag gcgactttgc
    28381 aatctattgc ttatcaagtg cgtgatatca tcgacaccat gcaagtggat actcagaccg
    28441 ccattcaagt actgaaggtg gatggtggtg cagccatgaa caacttcctc atgcagttcc
    28501 aggcggatat tttaggcatt gacattgcac gtgctaaaaa cttggaaaca acagctctag
    28561 gagcggcctt cctagcaggt ttgtcagtag ggtactggaa agacttggac gagttgaaac
    28621 tcttgaacga gacaggagaa ctctttgagc catctatgaa cgaatctcgc aaggaacaac
    28681 tctacaaggg ctggaagaag gctgtgaaag caactcaagt ctttgcggaa gtagacgact
    28741 aatactggca gaataaagcg atttatttag aaagtgtgta aatatggaat tttcaaaaaa
    28801 aacacgtgaa ttgtcaatta aaaaaatgca ggaacgcacc ctggacctct tgattatcgg
    28861 tggaggaatc acaggagctg gtgtagcctt gcaggcggca gctagcggtc ttgagactgg
    28921 tttgattgaa atgcaagact ttgcagaagg aacatctagt cgttcaacaa aattggttca
    28981 cggaggtctt cgctacctca aacaattcga cgtagaagtg gtctcagata cggtttctga
    29041 acgtgcagtg gttcaacaaa tcgctccaca cattccaaaa ccagatccaa tgctcttacc
    29101 agtttacgat gaagatggag caacctttag cctcttccgt cttaaagtag ccatggactt
    29161 gtacgacctc ttggcaggtg ttagcaacac accaactgcg aacaaggttt tgagcaagaa
    29221 agaagtcttg gaacgccagc caaacttgaa gaaggaaggc ttggtaggag gtggagtgta
    29281 tcttgacttc cgtaacaacg atgcgcgtct cgtgattgaa aacatcaaac gtgccaacca
    29341 agacggtgcc ctcattgcca accacgtgaa ggcagaaggc ttcctctttg acgaaagtgg
    29401 caagattaca ggtgttgtag ctcgtgatct cttgacagat caagtatttg aaatcaaggc
    29461 ccgtctggtt attaatacaa caggtccttg gagtgataaa gtacgtaatt tgtctaataa
    29521 gggaacgcaa ttctcacaaa tgcgcccaac taagggagtt cacttggtag tggattcaag
    29581 taaaatcaag gtttcacagc cagtttactt cgacacaggt ttgggtgacg gtcgtatggt
    29641 ctttgttctc ccacgtgaaa acaagactta ctttggtaca actgatacag actacacagg
    29701 tgatttggag catccaaaag taactcaaga agatgtagat tatctacttg gcattgtcaa
    29761 caaccgcttc ccagaatcca acatcaccat tgatgatatc gaaagcagct gggcaggtct
    29821 tcgtccattg attgcaggga acagtgcctc tgactataat ggtggaaata acggtaccat
    29881 cagtgatgaa agctttgaca acttgattgc gactgttgaa tcttatctct ccaaagaaaa
    29941 aacacgtgaa gatgttgagt ctgctgtcag caagcttgaa agtagcacct ctgagaaata
    30001 tttggatcca tctgcagttt ctcgtgggtc tagcttggac cgtgatgaca atggtctttt
    30061 gactcttgct ggcggtaaaa tcacagacta ccgtaagatg gctgaaggag ctatggagcg
    30121 cgtggttgac atcctcaaag cagaatttga ccgtagcttt aaattgatca attctaaaac
    30181 ttaccctgtt tcaggtggag aattgaaccc agcaaatgtg gattcagaaa tcgaagcctt
    30241 tgcgcaactt ggagtatcac gtggtttgga tagcaaggaa gctcactatc tggcaaatct
    30301 ttacggttca aatgcaccga aagtctttgc acttgctcac agcttggaac aagcgccagg
    30361 actcagcttg gcagatactt tgtcccttca ctatgcaatg cgcaacgagt tggctcttag
    30421 cccagttgac ttccttcttc gtcgtaccaa ccatatgctc tttatgcgtg atagcttgga
    30481 tagcatcgtt gagccagttt tggatgaaat gggacgattc tatgactgga cagaagaaga
    30541 aaaagcaact taccgtgctg atgtcgaagc agctctcgct aacaacgatt tagcagaatt
    30601 aaaaaattaa gaaaaaataa aagaggtgga gggcagcatt ccttgtcgcc cgtcccttct
    30661 ttttaatgga gacagaaaga tgatgaatga attatttgga gaatttctag ggactttaat
    30721 cctgattctt ctaggaaatg gtgttgttgc aggtgtggtt cttcctaaaa ccaagagcaa
    30781 tagctcaggt tggattgtga ttactatggg ttgggggatt gcagttgcgg ttgcagtctt
    30841 tgtatctggc aagctcagtc cagctcattt aaacccagct gtgaccatcg gtgtggcctt
    30901 aaaaggtggt ttgccttggg cttccgtttt gccttatatc ttagcccagt tcgcaggggc
    30961 catgctgggt cagattttgg tttggttgca attcaaacct cactatgagg cagaagaaaa
    31021 tgcaggcaat atcctggcaa ccttcagtac tggaccagcc atcaaggata ctgtatcaaa
    31081 cttgattagc gaaatccttg gaacctttgt tttggtgttg acaatctttg ctttgggtct
    31141 ttacgatttt caggcaggta tcggaacctt tgcagtggga actttgattg tcggtatcgg
    31201 tctatcacta ggtgggacaa caggttatgc cttgaaccca gctcgtgacc ttggacctcg
    31261 tatcatgcac agcatcttgc caattccaaa caagggagac ggagactggt cttacgcttg
    31321 gattcctgtt gtaggccctg ttatcggagc agccttggcc gtgcttgtat tctcactttt
    31381 ctaatctaga aaacaattat gttgatagag cttgggcaag agcccaattt cagcaaaaaa
    31441 tgaagtaaat cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca
    31501 actacagtca gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag
    31561 cacctgcaag caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa
    31621 aaatcgttga tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg
    31681 cgcaagcaga aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg
    31741 gtaaaaaaca agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta
    31801 caaattactt gagcaattaa ctaaaatata aaccctgcct ttatatctag gcagggttta
    31861 tattttagaa attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc
    31921 tatagtattc agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta
    31981 tgtagtatgg atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat
    32041 atgctccacc aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca
    32101 tataactgat tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat
    32161 gtattgtgtt gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt
    32221 cgatttcatt cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac
    32281 gtcgttcaat agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta
    32341 aaatatttac ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac
    32401 cagatacaac tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg
    32461 aaatgctaga catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag
    32521 acataacgga aactcctttg tatttttgat ttttttcaac ttttattata caataaaacc
    32581 aaataaaaag aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt
    32641 ttgatcgtta tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat
    32701 ttagacacag aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca
    32761 ttcgcttggg tctgctctac aataaaaaac aataaaaaat aaatagacgt attttcaaaa
    32821 aaaaaaaaaa atgcatattt atcttagcaa aacgacaatt taaatcgtcg tttttttgta
    32881 gtacgacggg catgtcgtat atctgaggtg taagtcctcg gtgggcacct gctaccggtg
    32941 aacccaatag cgattcccaa gcctgactat cgtgaggtag cagggagagg aagggatagc
    33001 gaaatcgtgg ctctacgaac aggaacgtga tagtaaggcg tatatagcgg ataaggaggc
    33061 ttcaaactct aaagtccaaa aaggtagtcg taacctatat gtgtaaatca cgagagtaat
    33121 tgaattcgga ctaaggtttg tgtgaaaaag ataaatcttt ctagagtcta aagactctgc
    33181 gtcagatttc ctattttcac tgtaaccttt taacgtcctc atatcttgta taaacgagga
    33241 aagatgtacg acttatcccg tgaggtttca tgagcgctga aagcgtagta acaacgaatc
    33301 atgagaagtc agccgagccc atagtagtga ggaaacttcc gtaatggaag tggagcgaag
    33361 gggtgaatac tcaaacagtc tggggagaga ctgtttgagg tctgtcgcta gaaagagaaa
    33421 acgacagatc gaagtaatcc tacttcactt gtgtctgtaa aatgagtggt ctgatagaac
    33481 tggactttga cacgtaatga ctagatgaag gttcaccaat ataagatgtc cctcaggcac
    33541 caaaacaaga aaggaatacg cacatgtcaa aactgctaga taagatatta tcacgcgaaa
    33601 atatgctgga agcctacaat caagtaaaat ccaataaagg ctcagctggg attgatggaa
    33661 tgactatcga agagatggat aattatctca gacaaaactg gcgcttgact aaggaactga
    33721 taaaacagag aaaatataag cctcaaccag ttcttaaagt tgagatacct aaaccagacg
    33781 gaggcatccg tcaactagga attccaacag ttatggatag aatgattcaa caggccattg
    33841 tccaagtcat gagccccatt tgtgaacccc atttctcaga tacgagttat ggtttcagac
    33901 caaataggtc atgtgaaaaa gccatcatga agctcttaga atacttaaat gacggctatg
    33961 agtggatagt ggatatagac ctagagaaat ttttcgatac agttcctcaa gatagattga
    34021 tgtccttagt acataacatt atcgaagacg gagatacgga atccttgatt cgtaagtatc
    34081 ttcattcagg tgttatcatt aatggtcaac gttataaaac actagttggt acaccacagg
    34141 gaggaaattt atctcctctc ttatccaata tcatgcttaa tgaattggac aaggaattag
    34201 aaaagagggg acttcgattt gtgcgctacg cagatgattg tgtgatacgg tcggaagcga
    34261 ggcagccgct aagcgtgtga tgtattcagt cagtcgtttt attgagaaac ggctaggttt
    34321 gaaagtaaac atgaccaaga ctaagattac cagaccaaga gagttgaaat atctaggttt
    34381 tgggttctgg aaatcatcag atggttggaa aagtcgtcca catcaagata gtgttcggag
    34441 atttaagctt aaattgaaga aactaacaca gaggaaatgg agtatagacc taacaagacg
    34501 tattgagcaa ctgaatttgt ctattcgagg atggataaac tatttctcat tgggaaatat
    34561 gaaaagtata gtcgccagca tagatgagcg cttgcgtact cgcctacgag tgattatctg
    34621 gaagcaatgg aagaagaaat cgagacgatt atggggattg cttaagttag gagttcctaa
    34681 atggatagca gataaggtat ctggctgggg cgaccattat caattagtag ctcagaagtc
    34741 ggtacttaaa cgtgctatat caaaaccagt cctggaaaaa cgtggactgg tttcgtgttt
    34801 ggattattac cttgaacgac atgcgttaaa agttagttga accgccgtat gccgaacggc
    34861 acgtacggtg gtgtgagagg ggctagagat tatcccctac tcgattaact cccctgaaat
    34921 ttattttaat tatgcaaatt tcacgtattt ttgatgctga gacgacgatc ctgggaactt
    34981 ttcagatatt tttttgacta tctaaatcta tcattagaaa agcttagagc gccaaaggat
    35041 ttgagcgttt ttctgatttt taagactttt tccagtctct ttttcgattg aagatgtaat
    35101 tattctacta actaactaac ttcttagtac tagccaacaa cgataatcat aattcctcct
    35161 aaaattagga ataataaagg caatagtttt tgttttttca tgtaaaaaac ctcacttttg
    35221 ttttctgcta ttttatgcta aaatattaaa aatcaaattt aattccaaag tttgtaacta
    35281 aagggggagc gctacatgtc taattcattt gtcaagttgt tagtctctca attatttgca
    35341 aatttagcag atattttctt tagagtaaca atcattgcta acatatacat tatttcaaaa
    35401 tcagtaattg ccacatcact agttcctatc ttaataggaa tatcctcttt tgttgcgagt
    35461 cttttagttc cgttggttac taaaaggtta gcgctaaata gggttttatc tttatctcaa
    35521 tttggaaaga ctatattatt ggcgatactg gtaggaatgt ttaccgtaat gcaatccgta
    35581 gcgcctttgg tgacctatct atttgttgtt gcaatttcca tactagatgg ttttgcagca
    35641 cccgtttcct atgctattgt gccacgctat gcgaccgatt tgggtaaggc taattcagcc
    35701 ttatcaatga ctggtgaagc tgttcaattg ataggttggg gattaggtgg actcttgttt
    35761 gcaacaattg gtctgttacc taccacgttt atcattttag tcttgtatat catttctagc
    35821 tttctgatgt tatttcttcc taacgctgaa gtggaggtgt tagagtcaga aactaatctt
    35881 gaaattttgc tcaaaggttg gaagttagtt gctagaaacc ctagattaag actttttgta
    35941 tcagcaaatt tattggaaat tttttcaaat acgatttggg tttcttccat tatacttgtt
    36001 tttgtaacgg agttattaaa taaaacggaa agttactggg gatattctaa tacagcatac
    36061 tctattggta ttataattag tggcttaatt gcttttaggc tatctgaaaa gttccttgct
    36121 gctaaatggg aaagtattct ttttcctctt gtagctatgg caatagtgac actgactatt
    36181 ctatattttc caaacgcaca gatgttttta ttattttcag ctttagttgg tatgttatcg
    36241 caactaaaag aagttcctga aagtgtattt cttcaggaaa cagtagagga aaatcattta
    36301 gttaatgtct attccgttct tgaagtgatt tctacattag cattttcagt atttgttttg
    36361 ctaatgagct atattactga gagttttggt attagcatca gtttttggct atcagccatt
    36421 tgtctgatga tagaagctat tttaatttat atcagacgag attattttaa atgagagagt
    36481 ggttaaaaag tctttaaaaa tcagaaaagc gcatagtatc aggtgttgaa aaaacttgat
    36541 attgtgtgtt ttattatggg aagatttact tcattgtctc ctgaaatgga gttttgaagc
    36601 aggatcactc tatttgaaaa tatacataga aaaaccgcat aatccttaaa ataagctgaa
    36661 atctattgga aacatacggt aaacaattga aaagatacta tataaagtgg tacaatggta
    36721 gaaaaataag ctagtaagaa tcactcttat tttagcgaaa aattacagaa atgaatggtt
    36781 tttcttgatg aaacagagaa aagaattgta cctctttctt ggtcggacag ccttgtattt
    36841 tcttatcttt ctagggctgc tttacttctt tagctatctt ggtcagggtc aaggaagctt
    36901 tatctataat gaattttaac ttgaaggaga atccctattg tgtcaaataa accaatagca
    36961 gatatgattg aaaccattga gcattttgct cagacacagc ctagctatcc tgtctataat
    37021 gttttggggc aggaacacac ttatggcgat ttaaaggctg attcggatag tttggctgca
    37081 gtcattgacc aactaggctt gcctgaaaag tctcctatgg ttgtttttgg tggccaagaa
    37141 tatgaaatgt tggcaacctt tgtagcgctg actaagtcag gtcatgccta cattccaatt
    37201 gatagccatt cggccttgga gcgagtttca gctattttag aagtagcaga gccaagcttg
    37261 attattgcca tttcagcctt tcccttggag caggtttcta caccaatgat aaatctagct
    37321 caggttcaag aagcctttgc ccaagggaac aactatgaaa tcacgcatcc agtcaaggga
    37381 gatgataatt actacattat ctttacttct ggtacgactg gtaagcctaa gggagtgcag
    37441 atttcacatg ataatctcct cagctttaca aactggatga ttacggataa ggaatttgcg
    37501 acaccgagtc gtccgcaaat gctggcacag ccaccttatt cttttgactt gtctgtcatg
    37561 tattgggcac cgaccttggc acttggtggt acgcttttca ctcttccttc agtcatcact
    37621 caggacttta agcaactctt tgcggctatc ttttcattgc caatcgctat ctggacatca
    37681 acaccatcct ttgcagatat ggccatgtta tctgaatact tcaacagtga gaaaatgcct
    37741 ggaatcacgc atttctactt tgatggtgaa gaattgacgg tcaaaacagc tcaaaaactg
    37801 cgcgagcgtt tcccaaatgc ccgtatcatc aatgcttacg gcccaacaga agcgacagta
    37861 gctctgtcag cagttgccgt gacagacgag atgttagcga ctctcaaacg cctaccaatc
    37921 ggctatacca aggctgattc tccaaccttt atcattgacg aggaaggaaa taaactgcca
    37981 aatggcgaac agggagaaat cattgtttct gggccagctg tttcaaaagg ttatatgaaa
    38041 aatcctgaaa aaacagcaga agccttcttt gagtttgaag gtctgccagc ctatcacaca
    38101 ggcgatgtgg gaaccatgac agatgagggc ttgcttctct acggcggacg catggacttc
    38161 cagattaagt ttaacggtta ccgcattgag ttagaagatg tctctcaaaa cctcaacaag
    38221 tctcgcttta tcgaatctgc tgtcgcagta ccgcgctata acaaggacca caaggtacaa
    38281 aatctattgg cttatgtcat cttaaaagac ggtgttcgtg agcagtttga gcgagatatc
    38341 gatattacca aggccatcaa ggaagacctg acagacatca tgatgtccta tatgatgcca
    38401 tctaaattcc tttaccgaga cagtttgcca ctaactccaa atggaaagat tgacatcaaa
    38461 ggattgatta acgaggtgaa taagagatga tggagttttt tcaacagctt cctcatttag
    38521 agccatatgg caatcctcag tattttgttt atgtgattgc tgcaaccttg cccatcttta
    38581 taggtctctt tttcaagaaa cgctttgcct ggtatgaagt gttggtaagt ctcttcttta
    38641 ttgtcaccat gttggtgggt ggaaagacca atcaactagc tgccttgggt atttaccttt
    38701 gctgggaaat attgctcctg cttttctaca agcattatcg aaaaagcaag gatggcaagt
    38761 gggtcttcta cttagttagt tttctgtccc tacttccgat tatctttgtc aaggtgcaac
    38821 cagctatcaa tggaacgcag tctttgcttg ggttcttggg aatttcttac ctgacctttc
    38881 gttcggttgg gattatcatc gagctgagag atggagtgat taaggatttt accctctggg
    38941 aattcctccg tttccttctc ttcatgccaa ctttctcgag tggtccaatc gatcgcttta
    39001 agcgatttaa tgaaaattat caggccattc ctgagcgaga tgagttgatg gatatgctgg
    39061 atgaatctgt ccgctatatc atgcggggct ttttgtataa gtttatccta gctcatgttt
    39121 taggagagac cttactccct cctctgaaga atttagcctt gcagtcaggt ggcttcttta
    39181 atctctatgc cttggcagtt atgtatactt ttggtctgga gctcttcttt gactttgcag
    39241 gttattctat gtttgctttg gccatctcaa acttgatggg aatccgtagc cctatcaact
    39301 ttaacaagcc ctttttatca agggatttaa aggagttttg gaatcgctgg catatgagtc
    39361 tgtccttctg gttccgtgac tttgtcttta tgcgaatggt gatggtgtta accagaaaga
    39421 aagtctttaa aaatcgtaat gtaacctcaa gcatggccta cattgtaaat atgctgatta
    39481 tgggattttg gcatggcgtg acctggtact atatcgccta tggactcttt catggactag
    39541 gcttggtcat caatgatgcc tgggttcgca agaaaaaaac gctcaataag gaacggaaaa
    39601 aagcagggaa ggctgcccta cctgagaatc gctggattca gtttcttggc atggttgtca
    39661 ctttccatgt tgtcatgttg tcattcttaa tcttttctgg attcttgaat aatctatggt
    39721 ttaaaaaata aaaggaaata aaatatggat atcaaatcag aagttattga aattattgat
    39781 gagttgttta tggaagatgt ttctgacatg atggatgaag atctttttga tgcaggtgtc
    39841 ttggatagta tgggaacggt tgagttgatt gtggagattg agaaccgttt tgacattcgt
    39901 gtccctgtaa cagagtttgg tcgtgacgac tggaatacag ctaataaaat catagctggt
    39961 attgtggagc tacaaaatgc ttaaacgctt atggatgatc ttcggaccgg tcttgatcgc
    40021 tggtttgttg gtttttctgc tcattttctt ttatcctact gagatgcatc ataatctagg
    40081 agctgaaaag cgttcagcag tggctactac tatcgatagt tttaaggagc gaagtcaaaa
    40141 agtcagagca ctatctgatc caaatgtgcg ttttgttccc ttctttggct ctagtgaatg
    40201 gcttcgtttt gacggtgctc atcctgcggt attagctgag aaatacaatc gttcctaccg
    40261 tccttatctt ttaggacagg ggggagctgc atcgcttaac caatattttg gaatgcaaca
    40321 gatgttacca cagctggaga ataaacaagt tgtgtatgtt atctcacctc agtggttcag
    40381 taaaaatggc tatgatccag cagccttcca gcagtatttt aatggagacc agttgactag
    40441 ttttctgaaa catcaatctg gggatcaggc tagtcaatat gcagcgactc gcttactgca
    40501 acagttccca aacgtagcta tgaaggacct ggttcagaag ttggcaagta aagaagaatt
    40561 gtcgacagca gacaatgaaa tgattgaatt attggctcgt tttaatgaac gccaagcctc
    40621 cttttttggt cagttttcgg ttagaggcta tgttaactac gataagcatg tagctaagta
    40681 tttaaaaatc ttgccagacc agttttctta tcaagcaata gaagatgttg tcaaagcaga
    40741 tgctgaaaaa aatacttcca ataatgagat gggaatggaa aattatttct ataatgagca
    40801 gatcaagaag gatttgaaga aattaaagga ttctcagaaa agctttacct atctcaagtc
    40861 gccagagtat aatgacttgc agttggtttt aacacagttt tctaaatcta aggtaaaccc
    40921 gatttttatc attccacctg ttaataaaaa atggatggac tatgctggtc tacgagagga
    40981 tatgtaccaa caaacggtgc agaagattcg ctaccagtta gaaagtcaag gttttaccaa
    41041 tatagcagat ttttctaagg acggcgggga gcctttcttt atgaaggaca ccattcacct
    41101 tggttggttg ggttggttgg cttttgacaa ggcagttgat cctttcctat ccaatcccac
    41161 accagctccg acttaccatc tgaatgagcg ctttttcagc aaagattggg cgacttatga
    41221 tggagatgtc aaagaatttc aatagataat ataatataga agagttcaag aatgaaacta
    41281 gttttcacgt tttttcttga ctcttttttt gcttgtgata taattaactg gtaaacaaaa
    41341 tgtcaaagaa tagtattttt ctcttaaaaa agagaagtct aaaaggaaag gagtcagata
    41401 tgagacagct agcaaaggat atcaatgctt ttttgaatga ggtgattttg caggcggaaa
    41461 atcagcatga aatcctaata ggtcattgca ctagcgaggt ggccctgacc aatactcagg
    41521 agcatatcct tatgctcttg tcagaggaat ctttaacaaa ttcagaattg gcccgtcgtc
    41581 tcaatgtcag tcaggcggca gttaccaagg ccattaagtc tttggtcaag gaagggatgt
    41641 tggaaacatc taaagattct aaagatgcgc gtgtgatttt ttatcagttg actgacttgg
    41701 ctcgtccaat cgctgaggag caccaccatc accatgagca tacactttta acctatgaac
    41761 aagtggcgac tcagtttact ccaaatgaac aaaaagtgat tcagcggttt ttgactgctt
    41821 tagtaggaga aatcaaataa tgagatatat tacggtagag gatttgtcct tctattatga
    41881 taaggagcct gttcttgaac atatcaatta ttgtgttgat agtggggaat ttgttacctt
    41941 gactggggaa aatggagcgg ctaagacgac gctcatcaag gctagtcttg gaattctgca
    42001 accacgcatt ggaaaggtgg ctatttcaaa gacaaatacg caaggtaaga aattgagaat
    42061 agcctatctt cctcaacaaa ttgccagttt taatgctggt tttccaagta cggtctatga
    42121 atttgtcaag tcgggtcgct atccgagaaa aggctggttc cgtcgtttga atgctcatga
    42181 tgaggagcat atcaaggcta gtctggactc agttggcatg tgggaacatc gagacaaacg
    42241 cttggggtct ctatctgggg gacaaaagca gcgagcggta attgcgcgta tgtttgcttc
    42301 tgaccctgat gtgtttatcc tagacgagcc gacaacgggg atggatgcag gaagtaaaaa
    42361 tgaattttac gaactcatgc accacagcgc ccatcatcat ggcaaggctg ttttgatgat
    42421 tacccatgac cctgaagaag ttaaggatta tgcggatcgc aatattcatc tagtccgtaa
    42481 ccaagactcg ccatggcgtt gtttcaatgt tcatgagaat ggccaggagg tgggccatgc
    42541 ttagtttatt atcttacgac tttatacaac gcgccttttt ggcggttatt gctatgagtc
    42601 ttttctcacc ggtattggga accttcctca tcttgcgtcg tcagagtttg atgagtgata
    42661 cccttagcca cgtctcactt tcaggtgtag cctttggtct ggttttgggg atttctccaa
    42721 ctgtttctac tattgccatt gtcttgattg cggcggtctt tctggagtat ctccgtacgg
    42781 tttacaagag ctttatggaa atcgggacag ctatcctcat gtcaacaggt ctggctgttt
    42841 ctctgattgt catgagcaag ggtaaaagct cgagttcaat gagtttggac caatatctct
    42901 ttggttcgat cgtgactatc agtgaagaac aggtcatttc cctctttgtc attgcggcgg
    42961 ttgttttgat tttgaccttt ctctttcttc gtcctatgta tatcttaact tttgacgaag
    43021 atacggcctt tgtggatggc ttgccagttc gtaccatgtc cattcttttt aacatggtga
    43081 caggggtggc tattgccctt atgattcctg cagcaggagc tcttctggta tcgaccatta
    43141 tggtcttgcc agctagtatt gccctgcgtc tggggaaaaa ctttaaatcg gttatgctgc
    43201 ttgccagtgc gattggcttt ttgggaatgg tagcaggact ttacatttcc tactatgcag
    43261 aaacacctgc aagtgcaagt attaccatta tttttgtaac tgtctttata ctaatcagtt
    43321 tagtaagacg ttttatcaaa taggagacga acgtgaaaaa aattagctta ttactagcca
    43381 gtctatgtgc cttgttttta gtggcttgtt ccaatcaaaa acaggcagat ggtaaactca
    43441 atatcgtgac aaccttttac cctgtctatg aatttaccaa gcaagtcgca ggagatacgg
    43501 ctaatgtaga actcctaatc ggtgctggga cagaacctca tgaatacgaa ccatctgcca
    43561 aggcagttgc caaaatccaa gatgcagata ccttcgttta tgaaaatgaa aacatggaaa
    43621 catgggtacc taaattgcta gataccttgg ataagaaaaa agtgaaaacc atcaaggcga
    43681 caggcgatat gttgctcttg ccaggtggcg aggaagaaga gggagaccat gaccatggag
    43741 aagaaggtca tcaccatgag tttgatcccc atgtttggtt atcaccagtt cgtgccatta
    43801 aactagtaga gcacattcgc gacagcttgt cagcagatta tcctgataaa aaagagacct
    43861 ttgagaagaa tgcagctgcc tatatcgaaa aattgcaagc cttggataag gcttacgcag
    43921 aaggcttgtc tcaagcaaaa caaaagagct ttgtgactca acacgcagcc tttaactatc
    43981 ttgccttgga ctatggactc aaacaagtcg caatctcagg cctttctcca gatgcagagc
    44041 catcagctgc tcgcttggca gaattgacag agtatgtcaa gaaaaataaa atcgcctata
    44101 tctattttga agaaaatgcc tcacaagccc ttgctaacac actttcaaaa gaagcaggtg
    44161 tcaaaactga tgtcctcaat cctttagaaa gtctgacaga agaggacacc aaggctggag
    44221 aaaactacat ttccgtgatg gagaaaaacc tcaaggcttt gaaacaaaca acagaccaag
    44281 aaggcccagc aatcgaacct gaaaaggcag aggataccaa gacagtccaa aatggttact
    44341 tcgaggatgc agctgtcaag gaccgcacct tgagtgacta tgcaggtaac tggcaatcag
    44401 tttatccttt ccttgaagac ggcacgtttg accaagtctt tgactacaag gctaagttga
    44461 ctggtaagat gacccaggct gagtacaagg cttactatac aaaaggctat cagacagatg
    44521 tgactaagat taacattact gataatacta tggaatttgt tcaaggtgga caaagcaaga
    44581 aatacactta caagtatgtc ggtaagaaaa ttttgactta caagaaaggc aatcgtggcg
    44641 tgcgtttcct ctttgaagcc acagatgctg acgctggaca attcaagtat gttcagttta
    44701 gtgaccacaa tatcgcccca gttaaggcag aacatttcca tatcttcttt ggaggcacaa
    44761 gccaagaagc cctctttgaa gaaatggaca actggccaac ctactaccca gataacctat
    44821 ctggccaaga aatcgcccaa gaaatgttgg cgcattgatg agaaatcgac tagttcataa
    44881 gagctagtcg gttttttgat actagatggc taacttcatt atagaccttt cagaactaag
    44941 ggaacctgaa aaaataaata aaactcttga aatatctgga cttatatgct agaatgtagt
    45001 tagtgtataa ggttcattag aacaccaaag cccctaacta gtgccatagt taagggcttt
    45061 tttgacgtat cttagcgatt taatgggtgt ttataggcta gtcagtcggt ctacttctta
    45121 ccatctagcc atttgcagac gaaatacaag ataattccag ctataacatc tgctataata
    45181 gtaagagcaa gctctggtat aaggctcatt agtttcacct cctctcacga acccatagga
    45241 acgtaatcgg taaccgatga caaaaatagt ataccacact aaatttagat catcaacctc
    45301 acttaatgct tgaactattg tagattatat gctaaaatgt agttaattga taaggttcat
    45361 tagaacacca aagcccctaa ctatggccgt agttaagggc ttttttgacg tatcttagcg
    45421 atttaacggg tgtttatagg ctagtcagtc ggtctactcc ttactatcta gccatctgca
    45481 gacgaaatac aagataattc cagctataac atccgctata atagtaagag cgagctctat
    45541 gataaggctc attagtttca cctcctctca cgaacccata ggaacgtaat cggtaaccga
    45601 tgacaaaaat agtataccac aataaattta gatcatcaag gtcacttaat tcttgaaata
    45661 tagggtctag gcgacaaagt ctttaaaatc agaaaaacgc ataatatcag gtgtgcaaaa
    45721 acttgatact atgcgtttta ttgtgggaag gtttactcca ttttctcctg aaattgagtt
    45781 tttgtccagc ctctgttttt ggggttgcta agaaaataat gtcatgtggt gaatatttgt
    45841 aaatcagtca gcagacagaa cgaatactct tcgaaaatct cttcacatca tgtcagcttc
    45901 gtctttccgt atatatgtga ctgacttcat cagttctatc tacaacctca aaacagtgtt
    45961 tcgagctgac ttcatcagtt ttcaaatctg tactttgagc aagctgagac tagcttccta
    46021 tttgattttc attgaatatc agaaacccat tctccatcaa ataattcgac tgcgtctaat
    46081 aatttttggt ctggcaaggt gtcagaaata aaggttgtgt atttggagag gggattaatt
    46141 ttaaaaaatc cagtcttgta aaatttagaa ctatcaatca gtaagatggt ttcatgggct
    46201 ttgtcaataa tattcttttt tgaaatagct tggctgagag aagcttcata aacatattgg
    46261 tcatcaatac ctcttgctga acaaaatgct aaatcgatat taaaatgatc taataaagaa
    46321 ttttccttat catagttgac tacggaacag gattgatgtt tgacctcgcc agatgtgata
    46381 aagattttgg agctatcttt aacagtttca gatagggttt gtgcagtatg taaaccattt
    46441 gtaaaaataa tcaaattatc aagttcagaa agatagggac agagttcgta gacagtcgta
    46501 ctggaatcaa gataaataca catgcctgac cgaataaagt ctttagcgag actagcgatt
    46561 agtctttttt gcctagtact ttctccttcc cgtatttgat gagaaagttc aattgtgttc
    46621 atagaggaca gggtcacgta tccgtgcttt cttttgataa gaccttgatt ttctaagaaa
    46681 attaaatcac gacgtaaggt acttgtgctg gagaaagtga tttctgccag ctcttttacg
    46741 gcaattcttt ttttcttttt gatgatttca atcaattcaa gtacacgttc atcttttatc
    46801 ataagctcct cctaatttat catttcaact atattatagc acaaattgga ggaatttgaa
    46861 ttatttttat gaatattggg ttaacatttg aacattattc aagtaagcgt tcacatattg
    46921 aaaaaataaa acgtggggat tataataaag ttaatcaagg acgaagagag aagaaaaatg
    46981 gaagcggttt tagcaataga tttaggtgcg acttctggaa gagcaatcgt tggttacctt
    47041 tctgaaaata aactagtaat ggaagaaata aatcgctttt ctaatctacc tattagagta
    47101 aaagggcatt tatcttggga tattgacttt ctactagcta aaattcttga aagtatccgc
    47161 ttggctaata ctagttacaa gattttatct atcggtattg acacatgggg agttgatttt
    47221 ggactggttg ataatgaagg taagctgtta ttacaacctg ttcattatcg tgatgaaaga
    47281 acaaagggag tgttaaagga aatatctgaa atgactgaat tagaaaaact gtattcagag
    47341 acaggaaatc agattatgga gataaatacc ttgtttcaac tctttaaggc acgtcaagaa
    47401 tctcctgact ctttctataa gaccaataag attcttttaa tgccagattt gtttaattat
    47461 ctcttgacag gtaagtttgc tacagaaaaa agcattgctt caacaactca attatttgat
    47521 cctaggagtc aaaactggaa tcagaatatc ttaaaactat ttgaattgga ttcatcttta
    47581 cttcctgaga ttgtttcaga gggaaatgtt cttggaagga taaaaaagga gtatggttta
    47641 ggcgatattc ctgttgtgaa tgtttgtagt catgatacag caagcgcgat tgtctcagta
    47701 cctaagacag aaggtagttt atttatttca tcaggtactt ggtctttggt tggagtggaa
    47761 cttacttcac cgcttcttac taccgaatcc ttcagttatg gatttacaaa tgaagtcggt
    47821 aaagatggag tgattacatt tctgaagaat tgtacagggt tgtggatcat agaggaacta
    47881 agacgttcat ttgaacgaag agggaaagcc tattcttttg atgatattag gacaatggtg
    47941 gagaaagaaa aagaaaatct tcctctgatt gatactgaat caactgaatt tgcaacagaa
    48001 tctgatatgc acaagacttt gacagaatat ctagcttatc atcatgaaac tagagagtgg
    48061 acagatggac aactatttaa gattgtttat gaaagcctag ctgaaacgta taggaaagcg
    48121 atagagttac tagaagaact aactcataag gtttataaga ggatatatgt gattggagga
    48181 ggtgctagag ccagttactt taaccaaatg attgctgata gaactggtaa agaggttctt
    48241 acaggtttga ctgaggctac agctgtgggg aatattgttg tgcagctcat agctatggga
    48301 caattaaaag ggatggaaga agctcaccat gttattgagg agtttctaca attagagagt
    48361 tattactccc aaaagaatta aaaagattga gagtttgtaa atttgcctcc ctcccccttc
    48421 ttaagttttg tacaagaagg ggggataatt ggtgaattga aaaatattta gtgttttgat
    48481 atgaggagga caagaatgtc agatgtaaaa caagaattaa ttaagtatgg caagaagcta
    48541 gtagaaacag atttgacgaa aggaacaggt gggaatctca gtgttttcga tcgtgaaaaa
    48601 caattgatgg caattacccc gtcgggtatt gatttctttg aaatcaaaga atccgatatt
    48661 gtagtgatgg atattaatgg aaatgttgta gagggagaac gcttgccatc tagcgaatgg
    48721 tatatgcatt tgattcaata tcaaactcgt gatgatatcg atgcaattat ccatgctcat
    48781 acaacttatg caacagtatt agcttgtctc agagaaccac ttccggctag tcattatatg
    48841 attgcagtgg cagggaaaga tgttcgggta gctgagtatg caacatatgg tacgaaagaa
    48901 ttggctgtga atgcagctaa agcaatggaa ggtcgtagag cagttttact agcgaatcat
    48961 ggaattttag caggtgcaca aaatttattg aatgcattta atattgttga agaagttgaa
    49021 tattgtgcaa aaatttattg tttagctaag aattttggag agccagtagt tcttcctgat
    49081 gaggagatgg atttaatggc agaaaaattt aaaacatacg gtcagagaaa atagggagga
    49141 tattaatgtt aaaacatata ccgaaaaata tttctccaga tttattgaag actttaatgg
    49201 aaatgggaca tggagatgaa atagtattag ctgacgcgaa ttatccttct gcctcatgtg
    49261 caaataagct aattcgttgt gatggcgtaa atattccaga attattagat tccattctgt
    49321 atttaatgcc attagatagt tacgtcgata gttcaattca gtttatgaac gttgtttcgg
    49381 gtgatgatat tcctaagata tggggtacct atagacagat gattgaaggt catggtacag
    49441 atcttaaaac gattacttat cttagaagag aagactttta tgaacgtagt aagaaagctt
    49501 atgctattgt tgctacagga gaaacttcac tttatgctaa tattatcctt aagaaaggag
    49561 tagttgttga aagagaaaat gtttaataga ggaattttag ttgccagtca tggtaatttt
    49621 gctagcggag ctctcatgac cgcagaaatg tttgttggtg agacaacaaa tgatagagtt
    49681 aggacattag gtttgatgcc tggagagaat attgtagagt ttgaacatta ttttaaaaat
    49741 caagtaaatg aactgttaga ctcaaatcaa gaggttatcg ttttgactga cttgattgga
    49801 ggaagtccta ataatgtggc tttgtcacgg tttttaaatt tggattcagt tgatattgta
    49861 acagggttta atatccctct cctagtggaa ttaatatcaa gttatgattc aaaaatcaat
    49921 ttagaagaaa ttgttcaaaa tgctcaaaat agtttgttta atgttaaaca acaacttaac
    49981 gtagaggagg aagaggattt atgtctatag agtttgttcg tattgatgac cgtctggtac
    50041 atggtcaagt tgtcactacg tggctaaaaa agtatgatat tgagcaagtt atcattgtta
    50101 atgatcgcat ctcagaagat aaaacacgac aatctatttt aaagatttct gcaccggtag
    50161 gtttaaaaat tgttttcttt agtgtaaaac ggtttgtgga agttttaaac tctgtgccaa
    50221 taaaaaagag aacaatgctg atatatacaa atccaaaaga tgtgtatgat tctattgaag
    50281 gaaatttaaa attggagtac ctcaatgtag gacagatgag taaaacggag gaaaatgaaa
    50341 aggtaacggg aggtgtagct ctaggtgaag aagacaaata ttattttaag aaaatagttg
    50401 ataagggaac gagagttgaa attcaaatgg ttcctaatga taaagttaca atgttggaaa
    50461 aatttttata aaaataattt aaggaggtac agtatatgct attcacacaa gcattactgg
    50521 tgacattagt tgggattatt gccactattg actataatgg accgttattt atgattcacc
    50581 gtccgttagt tacaagtgca atggttggct tagtcttagg agatttcacc caaggtgttc
    50641 ttattggttc agctcttgaa ttaacttggc tcggtgtaac aggtattgga ggttacactc
    50701 caccagatac tatttcaggt gcgattattg gtactgcatt tggtatttta tctggtcaag
    50761 gagaaactgc tggtatcgct atagcagttc caattgcagt tgctacccaa cagttggatg
    50821 ttcttgcaaa aactttagat gtttattttg tgaaaaaagc tgataatgat gctaaaaacg
    50881 gagattattc aaagatcggt ttttatcatt attcaagttt ggttttaatc acgttattta
    50941 aaattgtacc aattttccta gctattatgc ttggagggga atatgtggca gacttgtttg
    51001 ctaaggttcc accaatcgtt atgcagggac ttaactctgc aggtgcttta ctaccttcaa
    51061 ttggttttgg tatgctttta aatatgatgc tcaagaaaaa tatgtgggta ttcttgttga
    51121 ttggattcat ttgttctgtg tatggaggaa tgtcaaccat tgggatctca ctagttggta
    51181 ttgcggtagc atacttctac gatatgattg gaagtaaacc acaagaaaca acttcaagta
    51241 gtgatgttga ggaggatctt gatctatgat gaataataaa gtaactaaag ttgaacttaa
    51301 aaaagttttc aaacgaagtt ttatgtatgg ttcttcatgg aactatgaga gaatgcagaa
    51361 cctaggtttt ctatatacaa ttcttccagt attgaaaaaa ctatacccag acaaagattc
    51421 agcttctcct gcaatgaaac gtcaccttga gtttttcaat actcatcaaa cagcggcacc
    51481 atttattctt ggagttactt ccgctatgga agaacaagaa ggaaatgaag gtgcagcttc
    51541 aattactggt attaaagttg gcttgatggg gccactggct ggtctaggag atagtttgtt
    51601 ctggctgaca ctagttccta tctgttttag tattggtgcg tcttattcta aagacggcgg
    51661 tgctttaggt atctttatcg ccttaatatt gtttaatatt attaatattc ctgttaaata
    51721 tttcggtttg aaatatgggt atactaaggg ttctagtctt atccaagaaa ataatacaaa
    51781 aggaacattg aatcgcgtta cgagtatggc gacagcatta gggctagtac tagtgggtgg
    51841 tttgattcca tcaatggttg gtattaattt tggattagaa tttaagcagg gggaacttgt
    51901 tatttctgtt caagaaatga ttacaaaatt aattccagga tttatcccta tggctttgac
    51961 tttattaatg tgtaaattaa ttagaaaagg aaagaatccg gttgtactaa tctttagtgt
    52021 tatggctatt ggagttatcc tagttgtttt aggaattttg aagtagtaga aagtgtggag
    52081 gtggtatttg ggatatcacc tccattttgg aagagaggta aagagtgaaa ttatggtata
    52141 agaaagctgc ctcaaattgg aatgaagcct tgccgattgg gaacggtcat ttaggtggta
    52201 tgatttatgg ttcagctaca aaagaatgta ttcaactaaa cgatgagact atttggtata
    52261 gaggaaagtc agatagaaat aatccagact cactattgca tcttaaaaaa attcgggaat
    52321 atcttttaga tggagaaatt cagaaagccg aagaattgat aaagttaaca atgtttgcta
    52381 ccccaagaga tcaaagccac tatgaattac ttggggaact ttacattgag catatagata
    52441 ttcagtcttg tgctctttca ttgtatgaaa gagagctaga tttagataca gctatttcta
    52501 atgttgtgtt tgagcctaat agttgtaatt tacaaataaa aagagaatat tttacgagtt
    52561 ttaataagaa tattttatgt tgccgtatag tgtcatcagt tcaaaacaca ttaaatttaa
    52621 acattaattt gggtagaaat aaacggttta atgatgaagt atctaaactg gattcaagta
    52681 caattttaat gtcggcctct gctggaggta gaaaaggtgt tcagtttaaa gtagtatgtc
    52741 attctaaggt tacggatggt gaagtaagtg tattgggaga gacaatagtt attcggaatg
    52801 ctacagaggt atttctttat ctcaaatcaa tgacggatta ttggggaaat atagatattt
    52861 cttctcttca gggagaattt agtagtattg attactttac agaaaaagat gaacatgtaa
    52921 aaaaatatca ggagcaattt aatagagttg attttaaact agactatagt aaagattgtc
    52981 ttagcattcc aacgaatcta cttcttgaaa acactaaaaa gtatagtaac tacttgacta
    53041 acttgttatt tcattatgga agatatctgt taatatcgtc tagtcaaccg aatggtttac
    53101 ctgccaatct tcaaggaata tggtgtgatg aattaaatcc aatttggggt tctaaatata
    53161 cgattaatat taatactcaa atgaattatt ggatggtagg tccatgtgat ttaccagaag
    53221 tagaatatcc attatttgat atgctcgaaa gaatgagaga accgggaaga ctaaccgcta
    53281 agaaaatgta tggagctaga ggttttacag cacatcataa tacggatggt tttggcgata
    53341 cggctcccca atctcatgcc atgggggctg caatttgggt attaactatt ccatggttat
    53401 gtactcatat ttgggaacac tatttatatt tccaagatga gcgtattctt acggaacatt
    53461 ttgaaatgat aaaagaagca tttcttttct ttgaagatta tttatttgag gtggatggct
    53521 acttgatgac aggtccaagt gtctcaccgg aaaataaata tcgcttaaaa aatggtattg
    53581 aaggaaatgc ttgtctatca tctacaattg ataatcaaat tctaagatat ttttgtgatt
    53641 catgcattgg cattgcaaaa caattaggag acaattcgga ttttattagt cgtgtgaagg
    53701 agttaaaaaa gaaactacct aaaacaaaaa taggtagtaa tgggcaaatc caagaatggt
    53761 tagaagatta tgaagaagta gagcctgggc atagacacat ttcacctcta tttgggcttt
    53821 atccttataa tgagattgat attcataaaa ctccggaatt agcagaagca gctaaaatca
    53881 ctatcaatag gagattatca aacgctaatt ttttatcttc acaggagagg gagcaagcga
    53941 ttaataattg gttagtaagt ggtttgcatg ctagtacaca aacaggttgg agtgctgcat
    54001 ggctgattca tttttttgcg agactatatc aaggtgaacc tgcttataac cagattaatg
    54061 gtttgttaaa taatgcgact cttggcaatt tatttcttga ccatccacca tttcaaattg
    54121 atggtaattt aggtttggtg agtggaattt gtgaattatt agtacagagc catcataatt
    54181 ggttatcact aattccagct ttaccttctg cttggtcaga aggagaagtg aaaggtttca
    54241 gagtaagagg aggatataag gtatcgtttg cttggaaaaa tggggatata acattcctaa
    54301 aattggaagg aggaaacaaa gatcaaaaag taagagtaag aatatatggc aaaaatactg
    54361 atgtacaaaa tattgaattg gtatttaatt cagaaaaaat tattgagtta aatttttagg
    54421 tataagtcat gaataaagaa aaaataaaaa gaaaattaat cacaatattg tttgtatgta
    54481 ttgggatgtt atgttttgga ttgttagcag gagttaaggc tgataatcgt gttcaaatga
    54541 gaacgacgat taataatgaa tcgccattgt tgctttctcc gttgtatggc aatgataatg
    54601 gtaacggatt atggtggggg aacacattga agggagcatg ggaagctatt cctgaagatg
    54661 taaagccata tgcagcgatt gaacttcatc ctgcaaaagt ctgtaaacca acaagttgta
    54721 ttccacgaga tacgaaagaa ttgagagaat ggtatgtcaa gatgttggag gaagctcaaa
    54781 gtctaaacat tccagttttc ttggttatta tgtcggctgg agagcgtaat acagttcctc
    54841 cagagtggtt agatgaacaa ttccaaaagt atagtgtgtt aaaaggtgtt ttaaatattg
    54901 agaattattg gatttacaat aaccagttag ctccgcatag tgctaaatat ttggaagttt
    54961 gtgccaaata tggagcgcat tttatctggc atgatcatga aaaatggttc tgggaaacta
    55021 ttatgaatga tccgacattc tttgaagcga gtcaaaaata tcataaaaat ttggtgttgg
    55081 caactaaaaa tacgccaata agagatgatg cgggtacaga ttctatcgtt agtggatttt
    55141 ggttgagtgg cttatgtgat aactggggct catcaacaga tacatggaaa tggtgggaaa
    55201 aacattatac aaacacattt gaaactggaa gagctaggga tatgagatcc tatgcatcgg
    55261 aaccagaatc aatgattgct atggaaatga tgaatgtata tactggggga ggcacagttt
    55321 ataatttcga atgtgccgcg tatacattta tgacaaatga tgtaccaact ccagcattta
    55381 ctaaaggtat tattcctttc tttagacatg ctatacaaaa tccagctcca agtaaggaag
    55441 aagttgtaaa tagaacaaaa gctgtatttt ggaatggaga aggtaggatt agttcattaa
    55501 acggatttta tcaaggactt tattcgaatg atgaaacaat gcctttatat aataatggga
    55561 gatatcatat tcttcctgta atacatgaga aaattgataa ggaaaagatt tcatctatat
    55621 tccctaatgc aaaaattttg actaaaaata gtgaggaatt gtctagtaaa gtcaactatt
    55681 taaactcgct ttatccaaaa ctttatgaag gagatgggta tgctcagcgt gtaggtaatt
    55741 cctggtatat ttataatagt aatgctaata tcaataaaaa tcagcaagta atgttgccta
    55801 tgtatactaa taatacaaag tcgttatcgt tagatttgac gccacatact tacgctgttg
    55861 ttaaagaaaa tccaaataat ttacatattt tattgaataa ttacaggaca gataagacag
    55921 ctatgtgggc attatcagga aattttgatg catcaaaaag ttggaagaaa gaagaattag
    55981 agttagcgaa ctggataagc aaaaattatt ccatcaatcc tgtagataat gactttagga
    56041 caacaacact tacattaaaa gggcatactg gtcataaacc tcagataaat ataagtggcg
    56101 ataaaaatca ttatacttat acagaaaatt gggatgagaa tacccatgtt tataccatta
    56161 cggttaatca taatggaatg gtagagatgt ctataaatac tgaggggaca ggtccagtct
    56221 ctttcccaac accagataaa tttaatgatg gtaatttgaa tatagcatat gcaaaaccaa
    56281 caacacaaag ttctgtagat tacaatggag accctaatag agctgtggat ggtaacagaa
    56341 atggtaattt taactctggt tcggtaacac acactagggc agataatccc tcttggtggg
    56401 aagtcgattt gaaaaaaatg gataaagttg ggcttgttaa aatttataat cgcacagatg
    56461 ctgagactca acgtctatct aattttgatg tgattctata tgacaataat agaaacgaag
    56521 ttgctaagaa acatgttaat aatttgtcgg gtgaatctgt tagtctagat ttcaaagaaa
    56581 aaggagcaag gtatattaaa gttaaattac taacgagtgg agtgcctttg agtttagcag
    56641 aagtagaggt ttttagagaa tcagatggta agcaatctga agaggatata gataaaataa
    56701 cagaagataa agtagtctct acaaataagg tagctactca aagttcaacc aattatgagg
    56761 gtgtagctgc tttagcagtt gatggtaata aagatggaga ttacggacat cattcggtga
    56821 ctcatactaa ggcagattct aacgcttggt ggcaggtcga tctgggagaa gagtttacgg
    56881 tttctaaagt tgatatttat aatagaacag atgccgaacc tcagcgttta tctaattttg
    56941 atgttatttt tctatcttca tcaggagaag aagtttttag aagacatttt gataaagtag
    57001 ttgatggttt gttatcttta aaagtacctt ctgtaggggc taagctagtc aaaatagaat
    57061 taaaatcagc agctattccg ttaagtttag cggaagttga agtctatggt tcaaagagaa
    57121 ctccgaagaa actttctaat attgcattaa caaaagaaac tcgacagagt tcaacggatt
    57181 acaatggttt ttctcgtcta gcagttgatg gaaataaaaa cggagattat ggtcatcatt
    57241 cagtgactca taccaaagaa gattctcctt catggtggga gatagattta gcacaaaccg
    57301 aagaattaga aaagttaatt atttataata gaacagatgc tgaaattcag agattatcaa
    57361 attttgatat tattatatat gattcaaatg attatgaagt ttttacacaa catattgaca
    57421 gtttagaaag caataatcta tccatagact taaaaggact gaagggaaaa aaggttagaa
    57481 tttctttgag aaacgcagga attcctttaa gtttagcaga ggtagaggtt tatacttata
    57541 agtaatttta aaaattatca cccaggctac cgtaaatata atggagatgg tagtatgaaa
    57601 gaaacagaaa aataagagga aaatagtatg attcaacatc cacgtattgg gattcgtccg
    57661 actattgatg gtcgtcgtca aggtgtacgc gaatcacttg aagtgcaaac aatgaacatg
    57721 gctaaaagtg tggcagattt gatttcaagc acattgaaat atccagatgg ggaacctgtg
    57781 gaatgcgtga tttctccatc tactattggc cgtgtaccag aggctgcagc ttcccatgag
    57841 ttgtttaaaa aatcaaatgt ttgcgcaaca attacagtta caccatgctg gtgttatggt
    57901 agtgaaacta tggatatgtc tccagatatt cctcatgcta ttttgggatt taatgggaca
    57961 gaacgcccag gagctgtcta tcttgcagct gtactagctt cacatgctca aaaagggatt
    58021 ccagcctttg ggatttatgg aagagatgtt caggaagcta gtgacacaga tattccagaa
    58081 gatgtcaaag aaaaactttt acgctatgcg cgtgcagctc ttgcaactgg cttgatgaga
    58141 gacactgctt acctatcaat gggtagtgtt tcgatgggga ttggtggttc tattgtaaat
    58201 ccggatttct tccaagaata cctaggaatg cgaaatgaat cggtagatat gacggagttc
    58261 acgcgccgta tggaccgtag tatttacgac cctgaagagt tcgaacgtgc gctcaaatgg
    58321 gtgaaagaaa acgtaaaaga aggattcgac cataaccgtg aagaccttgt tttaagccgt
    58381 gaagaaaaag atagacaatg ggaatttgtt attaagatgt tcatgattgg acgtgactta
    58441 atggttggta acccaagact tgctgagctt ggttttgagg aagaagcagt tggtcaccat
    58501 gctttagtag ctggtttcca aggtcaacgc cagtggacag atcatttccc aaatggggac
    58561 tttatggaaa ctttcctcaa tactcagttt gactggaatg gtattcgaaa accatttgta
    58621 tttgcgacag agaatgattc actaaatggt gtgtctatgc tctttaatta tctattaaca
    58681 aatactccac aaatctttgc tgatgtgcgt acttattgga gcccagaggc tgttaaacgt
    58741 gtaacgggac atactttaga gggtcgtgct gcagctggct tcttacatct aatcaactct
    58801 ggttcttgta cattggatgg tacaggtcaa gctactcgag atggcaaacc tgttatgaaa
    58861 ccattctggg agttggaaga aagtgaagtg caggctatgc ttgaaaatac agacttccca
    58921 ccagcaaacc gcgaatactt ccgtggagga ggattctcaa ctcgtttctt gacgaagggg
    58981 gatatgccag taacaatggt acgtctcaat cttctaaaag gggttggtcc agtgctacaa
    59041 attgcagaag gttatacact tgaacttcct gaagatgttc accatacttt agataatcgt
    59101 acagatccag gatggccaac tacttggttt gctccacgtt tgacaggaaa aggtgctttc
    59161 aagtctgtct atgacgtcat gaataattgg ggagctaatc acggagccat aacatatgga
    59221 cacattggag cagacttgat taccttggct tctatgttga gaattcctgt caatatgcat
    59281 aatgtacctg aggaagatat ctttagacct aaaaattggt ccttatttgg aacagaagat
    59341 ctagaatcag cagactatcg tgcatgtcag ttgttgggac cactacataa ataaaacttg
    59401 tttatatagg aggtgaactt acgtccctcc tatcctttta aaaagatttg ttaaacaatt
    59461 cacaaataat tgaaaacgaa tacaaaaagt aatataatga tgttaaatag atagcgcgga
    59521 ggcgcaggag gaaaattata tggctacatt ttatgttccg gcagtcaacc ttattggtaa
    59581 aggtgttgta aatgaagtgg gtccttatat caaggaactt ggctataaaa aggcactttt
    59641 ggttacagat aagtacatcg aaggcagtga tattttgcct aaggttttaa aaccactgga
    59701 tacagaagga atcgaatatg tcatctttag cgatgtagag ccaaacccta cttgtaaaaa
    59761 tgtcacagat ggggtagctg ctttgcaaga acatggctgt gactttatca tcagtcttgg
    59821 cgggggttct ccacaggatg cagctagttg tatttctatc atggctacaa atggtggaaa
    59881 accacaggat tatgaagggc ttcataagtc tgctaaaaaa ggcttgccag ttgtggctat
    59941 caatacaacg gcaggaactt ctgcagaaat cactattaac tatgtgatta ctgatgaaga
    60001 acgcaaggtt aagatggtaa tggttgacaa gaatagcctt gctcttatct ctgttaatga
    60061 cccggaactc atgctttcca aacctaaagg cctgactgct gctactggta tggatgctct
    60121 gactcacgct gttgaagctt tggtaacacc tggtgcttat gatgtaacca agaaactgtc
    60181 tattggtgct attgagctta tcaaggaata tcttcctcgt gctgtagaaa atggacatga
    60241 tattgaagcg cgtgaaggta tggtcaatgc catcttcctt ggtggtatga gctttaataa
    60301 tgctggtctt ggttatgttc actcaatggc tcaccaactc ggtgcagtat ataatttgcc
    60361 acatggcgtg tgctgtgcca tgttgctacc agttatagaa cgtgaaaatg ctaaacgtgt
    60421 accagaagct tttcgcaatg ttgccaaagc cttgggactt catgtagaag gtaaatcaga
    60481 tcaagaatgt gccgattatg cgattgctga gattgagaag ctttctgaga cagtaggtat
    60541 tcctaagaaa ctgactgaac ttggtattga agaaaaagat ttcgactttg aatacctttc
    60601 taagaatgcc ttgattgatg cctgcgcacc aggaaatcca tttatgccaa ccttagaaga
    60661 aacgattgcc ttttataaag agttatttta gcaagagatt ggacgacaat aggacaattc
    60721 acctctaatt attgacattt caggaaaaat cgcagtaaaa acggcacagc cttctttaaa
    60781 tgtgctataa tactagaaaa atacttgtgg aggttccatt atggcaatat ttttcatgat
    60841 ttttctgatt gtttgtgtgc tcctattggt gatagtcaca ctgagtacag tttatgtggt
    60901 tcgtcagcag tcggtggcga ttattgaacg ctttgggaaa taccaaaagg ttgctaatag
    60961 cggtattcat attcgcttgc cttttgggat tgactcgatt gcagcacgga ttcagttgcg
    61021 cttgttgcaa agtgatattg tggttgagac taagaccaag gacaatgtgt tcgttatgat
    61081 gaatgtagcg actcagtacc gtgtcaacga gcagagcgtg acagatgctt actataaact
    61141 catacgtcca gaatctcaga ttaaatctta tatcgaagat gctcttcgct cttctgttcc
    61201 aaaattaacc ttggatgaat tgtttgagaa aaaagatgag attgcccttg aggttcaaca
    61261 ccaagtagca gaagaaatga ccacttacgg ctacattatc gtgaaaacct tgattaccaa
    61321 ggtcgaacca gatgcagaag ttaagcaatc catgaatgaa atcaatgcgg cgcaacgtaa
    61381 gcgggtcgca gcacaagaat tggcggaagc tgacaagatt aaaattgtca ctgcagctga
    61441 agcagaagca gaaaaagacc gccttcatgg tgtggggatt gcccaacaac gtaaggcgat
    61501 tgtggatgga ttggcagagt ctatcaccga actcaaggaa gccaatgttg gcatgacaga
    61561 agaacaaatc atgtctatcc tcttgaccaa ccagtatttg gataccttga atacctttgc
    61621 ctctaaagga aatcaaacca tctttttacc aaatactcca aatggtgtgg atgatatccg
    61681 aacacaaatc ttgtcagccc ttcgcgctga gaagaaataa tagactaata ctcttcgaaa
    61741 atctcttcaa accacgtcag cgtcgtcttg ccgtatagat gttactgact tcgtcagttc
    61801 tatctgcaac ctcaaaacag tgttttgagc aacctgtggc tagtttccta gtttgctctt
    61861 tgattttcat tgagtataaa gagcttggca acaggctctt tttgtattgc gtttattaag
    61921 aaaaacaaaa aacatcgata tacatttaac taaaaattat tgtatgtcat ctcccttaat
    61981 taggaatgat aagggaataa ctagaaagat ttgtgaatac aaactatttc tgatatacaa
    62041 aatatacagt aataatgaat gatgggagat gggatgaaag aatttcaatt tgagagaaag
    62101 cagcgttttt ctttgaggaa atatgcaata ggagcttgtt cggtcttgct aggaacgagt
    62161 ttattttttg ctggtatggg tgctcagcct gtacaggcta cagaaacgag ttcagcacta
    62221 atttcaagtc attatttgga tgagcaggat ttatctgaaa agctgaaatc tgagttgcaa
    62281 tggtttgaat tagaaaacaa gcttttgaac ttatgggagc attaggttac tatgaaggat
    62341 ttgttcctta tgtttcaaat caatacaaaa accaaactga agaagaaggc aaaccgctat
    62401 ctgataaata tattttcgaa aaaatcttag gaaaaacata tgcagccttc aaaaaagatc
    62461 aaattaatga gcgtgtcgag aaattaggta agttaaaacc tattacaata aattacaacg
    62521 gaaaatcaga agtaattgat agtaaagaaa aattacaaaa gcttatgaat aaagccgtta
    62581 aagacgaagt ggctcaaata tagtaaaatg aaataagaac aggacaaatc gatcaggaca
    62641 gtcaaatcga tttctaaaaa tgttttagaa ggagaggtgt actattctag tttcaatata
    62701 ctataaaatc aggcaatacc acggctaaaa agtttgagtt tatcgaaaca ccagtgcaaa
    62761 aactgaaaaa agcgatttat aaagctcatc tcaaagattc agatgacttt agaccagaaa
    62821 catccacacc aaatcttttt gaaagctgtt tgaagctttg tccttgcttt cttagttcat
    62881 agatctgaac tttatcttca taactcaatt tcataataaa acaccccaaa agttagattt
    62941 attctgtcta acttttgggg tgcagttcat taatcggtcg attttttttg gtagaaacag
    63001 ttgcctgatt aagttgcaag tcgatagacg gcttcggcat aaatatccat agcacggtac
    63061 aaatcttcta gaacggcaca ttcatttgcc tgatgttctg tctgcttcgc tcctgggaat
    63121 aaggcgccga aggctacaca atttggcatg gtgcgagcaa aagtggcacc accggatgaa
    63181 atagcaggac tgttatcgcc agtcttttct tggtagattt gcatcagtgt gctaacgagt
    63241 ttactgtctt ttgcgacgta tagaggcgct agatagtcaa actcttcgta gcggagttgg
    63301 tagttttgtg cacatcttgt aagcaactct actagttctt ccttatcagc taagacagga
    63361 gtccgaatgt caatacggat ttcagaacgt tcatgattga tcatgagacc tgcgacatta
    63421 aaggataggt gaccagaagg ttcatctgct atatcaccaa agatttgtct tcctgtgccg
    63481 tcttgacctg cttgtgttgc aagaaaactg agagcagggt gttcttggag aggagcaaga
    63541 atggtagcta gtcggatgac agcattgata ccttgactag catccttagc atgctttggc
    63601 actccgagaa ccgttacggt ttgttcagtg gattggtaat cataaccagc ttctttgaga
    63661 ccgttacaaa cctgttcata gaggggacct tggtagttgg ccttgtctgg tacaacgtta
    63721 aaggcgcctc ctacttcaag ctctagttga tccgatccag ggccatgaag tttgacctgt
    63781 agaagccctt tttcagcata ggtcagagga aaagatgagt caggtgcaaa gcccatgctg
    63841 gcctgttctt cgatggtatt gtagcgtgcc atgcagcgcc agagggtttc ctcatcggta
    63901 ccaaagataa agcgtacgcg ctttttgaac tgaatacctt ggtccagcaa gctttttact
    63961 gcatagagag ctgcgagcga agggccttta tcatcttgga caccacgtcc gaatacccag
    64021 ccgtctttga tagttgcttc aaatggcggt gtctgccaat ctgcttcatc acctgatgga
    64081 acaacatcca aatgacagag aatggccaga agctctgctc cctgaccgat ttctgcatat
    64141 ccgtaataac ctttagggtc aagataggta gtgaaaccta tgtcttgaca aatctctaaa
    64201 gttttttcta ggacatcttg gattgcttgt ccaaaaggtg ttccattttc tccttcattg
    64261 agtactgaag gataggaaat caaggttttt aatgatataa gaaattcatc tttaacttga
    64321 tttgttatat ctattttcat ggaatcacct cactcactat tttataggaa tggaaggaag
    64381 gttccaagga gaagaagggc gatggtcact acaataatag cgactacgag tttgcccatg
    64441 aatttccacc aagtaccaat gttgatacgt ccaagtgcaa gagctcccat cacaatacca
    64501 gatgttggtg caatcaagtt caagacacct gaagcagatt ggtaagcagt gataatcaag
    64561 ctaggacgga catttacaaa ttctccaagt ggagccatga tacccatagt tgcgctggca
    64621 agaccagatg aagatgggat caagaatgac ataggtagat agaagatata agttacaacg
    64681 ataaagactt gtgaagatag accgctcaag ccttctttac cccagttgag gattgtatcg
    64741 gtaatcatac cgtcgttcat gataacttga ataccacgag caatcgctac gatcaaggca
    64801 acactgagca agtcagcagc accattcatg aaggaagaga taatcttatc ttctttaaga
    64861 ccataaataa caccaatcag gatacccata aaggcaaaga gcattgcgcc ttctgggaag
    64921 taccaagtac ctagtgcaga agtagatgaa ccgacaatat taccaataac tggaagacca
    64981 gtcaaccaag cattaaagtc atcaaaaatg gtaacgccaa ggtctgtcca tggaatgaag
    65041 ctcaatacca tcaagatgaa tgtcaacaca aataagaaga gaactgattt ttgtttgctg
    65101 ctaagtgtag attctacaga tgaagattct tccacgttaa agtgtttcaa atcttctttg
    65161 cgagtactat aaaccagtga cttagtcgga tctttttgaa tcttatccgc ataacggtaa
    65221 acaaaccaag tactaagagc agtcaaggta acccagaaga tcagacgaag tacgataccg
    65281 tcccctgtac caactcccgc agtcgctgaa gcaatacctg tcgcaaatgg attcagagta
    65341 gatgccaaac agccgatttg agaaccgagc aaaataattg caacaccagt caggctatca
    65401 aaaccaacgg ccatcataac tggcacaagg agtggataga aagccattgt ttcttcaccc
    65461 ataccataag ttgtaccacc gagggcaaac aaaggcatca gtaccaaaat taacattttt
    65521 tcgcggccct tatacttctt cacgatagag gcaatcccta cgtcaagagc accagttttg
    65581 ttgacaatgc caaggaaacc accaaccata aggatgaaga aggctacatc aatcgctgcg
    65641 ctcgtttctt taatgagcga accttcctct ggatgagtac ctagcatagc ccgaatcggt
    65701 gccatgagga catcccaaat cccttgtgga ttttgaggct gagtctcgta aataccttct
    65761 ataaaggccc ccgcagggat aaaccaagtt agcactgcca taatagcaat gattatcaat
    65821 aatacggtgt aagatgaagg catcttaaac ccttttttag ctttttcact catttgtttt
    65881 tcctcctgat gtctaacaaa gtgtaaaaaa ccaactactt tcttaaataa acatttaaga
    65941 aaacgctttc tatttatatt tgttttacca tattaaagtc taaaaaacta atatcttttg
    66001 aaatattgta catgttttca agaataattt ctaatttgat ataaagatac tagaaataga
    66061 atacatctta ttagtaaaac aacttatcct ttttcaataa ttgttccact ttcagattca
    66121 atcaaggcgc ctagattttc aagggaagta ataactgctt ttccttctgg acgaccattg
    66181 acaaaagcga tagctgcttc tacttttgga agcatgctac ctggtgcaaa ctgatcttgt
    66241 ttgatatatt cttccagctg ggcaacattc acatgttcca atttttcctg gtttggcttg
    66301 ttgtagttaa caaatacata atctacacct gtcaaaatga tgaagaggtc tgcatcaacc
    66361 aattctgcca aacgttggga agcgaagtct ttatcaataa ccgcttcgac accagtcaaa
    66421 tgtccattgt tttctttgac gacgggaata ccgccaccac ctgcagctac gacgacttga
    66481 ccattattta aaagagtacg gatggtttca atttctttga tgtcaacagg ttttggtgag
    66541 gcaacgacct tacgccagcc acggccagca tcttccttga aagtcgctcc gcttttttcg
    66601 gcttctgctt ttgcttcttc ttctgaatag aaaggaccga ttggtttact caagttaaca
    66661 aaagctggat catttttatc tacgacaact tgcgttacaa cagaggcaac atttttttcg
    66721 atgccttcat ccaagagagc attttgcaaa gcatttttca accagaaacc gatgctacct
    66781 tctgtcatag cgacaagtga gtcgagtggg aaggcagggt tcttttcaga gtctgatgcc
    66841 aaatgttgga gcaagagatt cccaacttga ggtccattac cgtgagtgat aatcaaatca
    66901 tctccatttt taatcaattt tacaagatgc ttagctgttt caactaaagc ttcttgttga
    66961 gcctttgctg atgggtcaga agaaagaatc gcatttcctc ccaaagctac tacaatttta
    67021 cgatttgcca taaattctcc tttatcacac tcaatagaat gcgtttagat ttcaatttaa
    67081 tgatttttca catattttat aagaaataat agattaccat tacataaaag aggaccggac
    67141 taaagctatt agtcgcagcc ctcatagctg ttggtagacg gtttattatc taaaattata
    67201 ctttaggaat ataaaggtta ccaagtgtcg cagccataac agctttgata gtgtgcatac
    67261 ggttttctgc ttgatcgaag tggcgagcgt acttgctgcg gaagacttcg tctgttactt
    67321 ccatttcttc tacaccaaat ttttcagcaa cgtctttacc ataaacagtg tgagtatcgt
    67381 ggaatgctgg caagcagtgt aggaagatca agttttcatt gcctgctttt ttaactaagt
    67441 ccatattgac ttggtaaggt ttaagaagag ctacacgttc tgcgaatttg tcttcttcac
    67501 ccattgatac ccaaacgtct gtgtaaagaa cgtctgcatc tttaactgct tcatcagcat
    67561 cttcagtgat gagaacatgt gcgccacttt ctttagcaaa tccttctgcc aattcaacga
    67621 tttctttttc tgggaagagt tcttttggtg agaagatgtg aacattgaca ccaaggatag
    67681 cacctgttac gagcaagctg ttggcaacgt tgttacgtcc atcaccacag tataccaatg
    67741 tcaagccttc caagcgaccg aagttttctt gaacagtcaa gtagtcagcg agcatttgag
    67801 ttgggtgcca ttcgtcagtt agaccgttcc atactggaac gcctgagaat tctgccaatt
    67861 cttcaaccat acgttggctg aatccgcgga attcaatccc gtcaaacata cgtcccaata
    67921 ctttagcagt atcttcagta gattcttttt tacccaactg aatatcattt gctccgaggt
    67981 attctgggtg agcaccaagg tcgatagccg cagttgtaaa ggctgcacga gtacgagtag
    68041 atgttttttc aaataggaga gcgatattct tgccagcaag gtagtggtgt tgaatattgc
    68101 gttttttcaa atctttcaag tgagctgaaa gaccaataag gtattctaac tctgcacggg
    68161 taaagtcttt ttctgctaag aagctgcgtc cttggaatac tgaatttgtc attttattat
    68221 ttcctctttc tattttttac attttctatt gacgaatatc gaacagcgat tacacttctt
    68281 cacgttcaaa tggcatagac atacaacgag gtccaccacg cccccgaacc aattcacttc
    68341 cgcgaatctt aatcaagcga agcccgtatt cttccaaaat cttattggtc acggtattgc
    68401 ggtcataaac aactaccaca ccaggtgcga tggtcaaagt gttagaaccg tcgttccatt
    68461 gttcacgcgc agctgctacg atattgccac caccgcaacg aatcaaatga actttttcta
    68521 catcaaggtt ttgagcaaga agttcagcta agtcaccttt ctcttcaacg attttaagtt
    68581 tttcgttttc gtaagtaact gagtaaacgt gaaggtcgcc ttcgatttct gggtgaatag
    68641 tgaacttgtc atagtctacc atagtgaaga cagtatccaa gtgcatgaat ttacggttgt
    68701 tagcaaattc aaaggccaaa actttcttga agccaacatt tttcttgaag atgttgacca
    68761 aaagtttttc tatagaagct gcgtctgtac gttgagagat acctactgca aggacgtctt
    68821 tagaaagaac tagctcgtct ccaccttcga tacgcgtatc ttcttcacgg ttgtagacca
    68881 aatccacttt tcctccatag attgggtggt atttgaagat atacttaccg tagagtgttt
    68941 cacggttacg agtgtctgca aacatgtggt taagcgatac ggcgtttcca attgttgcaa
    69001 atgggtcgcg agtgaaatag aggtttggca tcgggtcaat tgcaaatgga taatctgatt
    69061 caactaagtc agttagatct ttagcttcgt caggaatttc tggcaattca actttttgaa
    69121 tcccagccat tgttttttca accaattctt ggttgtcctt gatgccgtga agcaattcac
    69181 gaatagcaac cttggtttga cgatcacgga tgttggcttc gtctaagtat tcctcgataa
    69241 attgatcgcg gatttctgga gaggtcaatg attcagcagc gagttgttct aggtagagaa
    69301 cctcaattcc ttcatcgcga agagcttggg caaatgcatc atgttctttt tgagcatctt
    69361 ccaagaaagg aatatcatca aaaagaagcc tttcaagata gtccggcaac aagttttcta
    69421 actccttgcc tggacggtgt aacataactt ttttcagttt cccaatttct gagaagacct
    69481 gaattggatg tgaagacatg tattttcctc cttaaaaatt ttgacttggc accattttgg
    69541 gtaccgctta catgtatgtt ataacgcaat tcctaggtaa tgtcaatggc tataatttct
    69601 cggaaaataa tataaattat gatatttagc acaattttat gttattatac acaacatagg
    69661 atggaataca tatatacaaa tgcataaact tctattaaag aggatataaa atttttttaa
    69721 aaaatttttc aaaaaataca caaataacca aaaagtgtcc aattatcatc tggttatcac
    69781 ttggatctgt ataaagagaa atgtttgtgt gaaaggataa aaagatgcaa cattcttttg
    69841 aagatagatt ttggagaagc atttcttgct caattgtaca aattatagaa tcttttctga
    69901 gtatttagga agagataatt atcttattga ccctcttttt attttttgtt atagtcgacg
    69961 agatgatagt ttagaataat cacttattca caatctgtgg aaaagtctgg agagtgaatg
    70021 gtcttcacac aatgacctga aagaagcctg agaataatta tggagagtag cattctgaga
    70081 ggtgttagca gaaccatatg acagagctgt ttgaagaggg aacattgagg agcaaaatcc
    70141 tgagcctacc agttggagtt ggaaagagct ggcggttaga tcatttttta ttatccacaa
    70201 cctgtggata accttgtgaa caagagaagt tgctaaagaa ggagatatat aacgatgaag
    70261 aaaatcaaac cgcatggacc gttaccaagt cagactcagc tagcttatct gggagatgaa
    70321 ctagcagctt ttatccactt cggtcctaat accttttatg accaagaatg ggggactgga
    70381 caggaggatc ctgagcgctt taacccgagt cagttggatg cgcgtgagtg ggttcgtgtg
    70441 ctcaaggaaa cgggcttcaa aaagttgatt ttggtggtca agcaccacga tggctttgtc
    70501 ctttatccga cagctcacac agattattcg gttaaggtca gtccttggag gagaggaaag
    70561 ggcgacttgc tccttgaagt atcccaagct gccacagagt ttgatatgga tatgggggtc
    70621 tacctgtcac cgtgggatgc ccatagtccc ctctatcatg tggaccgaga agcggactac
    70681 aatgcctatt atctggctca gttgaaggaa atcttatcaa atcctaacta tgggaatgct
    70741 ggtaagttcg ctgaggtttg gatggatggt gccagaggag agggcgcgca aaaggttaat
    70801 tatgaatttg aaaaatggtt tgaaaccatt cgtgacctgc agggcgattg cttgattttt
    70861 tcaacagaag gcaccagtat ccgctggatt ggcaatgaac gagggtatgc aggtgatcca
    70921 ctgtggcaaa aggtgaatcc tgataaacta ggaacagaag cagagctgaa ctatcttcag
    70981 cacggggatc cctcgggcac gattttttca atcggagagg cagatgtttc catccgtcca
    71041 ggttggttct accatgagga tcaggatcct aagtctctcg aggagttggt cgaaatctac
    71101 tttcactcag tagggcgagg aactccactc ttgcttaata ttccgccgaa tcaagctggg
    71161 ctctttgatg caaaggatat tgaacgactt tatgaatttg cgacctatcg caatgagctc
    71221 tataaagaag atttggctct gggagctgag gtatctggtc cagctctttc cgcagacttt
    71281 gcttgtcgcc atttgacaga cggccttgag accagctctt gggcaaacga tgcagacttg
    71341 cccatccagt tagaactcga cttaggttct cctaaaactt ttgatgtaat tgagttgaga
    71401 gaagatttga agttaggcca acgtatttct gctttccatg tgcaagtaga ggtggatggt
    71461 gtctggcagg aatttggcag gggcttcaca gttggtcata agcgcctctt gcgaggtccg
    71521 ctagtagagg cacagaaggt gcgcgtgatg attactgaag cacaatctat gcctctactg
    71581 accaagattt ccctttataa aactcctgga ttatcaaaaa aagaagttgt tcaggaacta
    71641 gcatttgcag aaaaaagcct agctgtggca aagggagaga ctcttcattt taggattgaa
    71701 cgtagtgaaa gtagctcctc tttagaggct aagatttcga ttcaaccggg gacaggtgtc
    71761 catggtgtcg cctatcagga tgagattcaa gttcttcaat tccaagcagg ggaaagcaaa
    71821 aaagatttgc atctaccaac cctgtatttc gcaggagata aaaccttgga tttctatctg
    71881 aacctaacgg tggatggtca gcttgtggat caacttcaag tccaagtttc ataaaagaag
    71941 aacctttgcg cgatgcaaag gttcttttgg ttattaatga cttggtaacc agctgagggt
    72001 gaaagttagt tgttcagctt ttaagaggtc ttggtgttga atagttgata cgagtgtttt
    72061 gtccagtcgg cattctttga caaagttaaa atggttgtgg ttttgtttag tatggatatc
    72121 cagccattta tcttctttag cgaggtagac tcgtagatgg tcaaagagag agattccgag
    72181 gtcatagctt ggttttcctg gacaggttgg ataaaatccg agagctgacc agatgtacca
    72241 agcagagaga ctaccattgt cttcatctcc aggataggct tcccaacttg ggtgaaaagc
    72301 tttctgacgg agcgtcttga taagaagggc agtgtagtca gggtaatcgc tgtaacggaa
    72361 gagataagga atgtggaaac taggctggtt ggaaatggct atctgtccaa aaggagcagt
    72421 agccatctcg ctcatttcgt gaatttcgta accatagcct gttgtttcaa agaggggagc
    72481 atcttgacag gctttcaaaa gatagttgct aaaggtttct tttccaccca tcagttggat
    72541 taagccaggg atgtcgtgga gaacgcctaa agtagcttga atggcagagc attcagcgta
    72601 gtctcgcccc caactataag gagagaagtc agggtgaaag tttccttgat tgtctcgtgc
    72661 tcgcatgtaa cctgtctcag cgtcaaatag ctggcggtaa ttttgtgaag cagccttgta
    72721 ggtttcagcg atttctatgt tttttagttt tttggcacag ttggcgatac aaaagtcact
    72781 ataggcatag tctagagtat ggctaacact ttcgtggtgg tcggtagaga ggtaacctag
    72841 ttcttggtat tgggctagtc cgtggcggcc attgatgccg agagggtcgg ctttgctggc
    72901 tgttttgagc atggcttgga agagttctcc ttctaggtcg ggggccatgt ccttgcaggc
    72961 gctatctgcg ataataccgt ctaaaagtgt acctggcatc ataccccgtt catctggagc
    73021 cagccatttt ggaaggaaac cagtatcgcg gtagctattg aggaaacctt ctaaaaagcg
    73081 ttgatagtgc tccggtatga taagggcaaa gagggggaag gtggtgcgga aggtatccca
    73141 gaaaccattg ttgctaaaga ggacaccagg cttgacagta ccagtagcca gatccatgtg
    73201 gatggcttgc cctgactcat caacctcata aaaagtctgt gggaagagga agagtctgta
    73261 gaggcagtgg tcaaagaagg ttcggtcagc ctctcctgtc tctataatgt caaaacgatg
    73321 gaggagattt tcccaatccg cttgggcact tgttttacag ctatcaaaat cttcttgagg
    73381 tagattgatt agagcttgag aaggagagat gaaagaagtg gctagttgca tctcggtttg
    73441 actacttgct aagtcaattc gccagtctcc agcttcttgg ctgatagcaa gaatatccgt
    73501 gttcatttgc agggcagtga acatcgttag cgaatttttg ttagtttcag ttttaccttc
    73561 ttgttgcagg gcaagagttc gcttatctac ttgctctact gtcagttcat ctgttgcgtg
    73621 aagatagagg gagagggctt tgccttgctt ttgcttcaaa cgaatagaag caccgtagca
    73681 agtcggtgtg agctgggttt caatctgata gcgcagggag aaaatcttta gataatgagg
    73741 ttggaaagag gccttatccc tatcatagga agattggcgg tgaaagaggc tgtctccacc
    73801 cagttgactg gtgacaggtg tcagaaggag ccaagagtag tccccaatcc aaggactggg
    73861 ctggtgagtt aatcgaatcc cctgaaagat aggcagatgt ggatcaaaaa accaagatcc
    73921 atcctggtca ctggtctggg gcacaaagta attcatccca aaaggcacgc ctgtgtatgg
    73981 cagggtattt ccccgagaaa aggcatgctt gttggtagtt ccaaagcggg tatcgatggt
    74041 ttcaagtagt ggtttcatag tctttccttt agctgttttt ctacattata tcagaaaaag
    74101 agggccttta gaaaaggagt ttcaaaaata actattttgt agaaaaatga ctatcatttg
    74161 tgtatgtatt ttctgtctca aaagctatat actgaacatg aaacttgttt gaaagaggta
    74221 aaatttaaaa tggtttattc gaaagaaatc gtcagagagt ggctagatga agtagcagag
    74281 cgggctaagg actatccaga gtgggtggat gttttcgagc gttgctacac cgataccttg
    74341 gacaatacgg ttgaaatctt agaagatggt tcaacttttg tcttgactgg ggatattcct
    74401 gccatgtggc ttcgagattc gacagcccaa ctcagaccct accttcatgt agctaaaaga
    74461 gatgccctcc tgcgtcagac cattgcaggt ttggtcaaac gtcagatgac cttggtactc
    74521 aaggatccct atgctaactc cttcaacatt gaggagaact ggaaagggca ccacgagact
    74581 gaccacacag accttaacgg ctggatctgg gagcgcaagt atgaggtgga ttcgctttgc
    74641 tatcctttgc agttggctta tctcctctgg aaagagactg gcgagactag tcagtttgat
    74701 gagatttttg tcgcagcgac taaggaaatt ctccatctgt ggacggtgga acaagaccac
    74761 aagaactctc cttatcgttt tgtccgagat acggaccgta aggaagacac cttggtaaat
    74821 gatggctttg gacctgactt tgcagtgaca ggtatgactt ggtcagcttt tcgtccgagt
    74881 gatgactgtt gccagtatag ttacttgatt ccgtcaaata tgtttgctgt agtagtcttg
    74941 ggttatgtgc aagaaatctt cgcagcatta aacctagctg atagccagag tgttattgct
    75001 gatgccaagc gtcttcagga tgaaatccaa gaaggaatca aaaactacgc ttacaccacc
    75061 aacagcaagg gcgaaaagat ttacgctttt gaagtggatg gcctaggaaa tgccagcatc
    75121 atggatgatc caaatgtacc aagtctacta gctgcgccct atctgggcta ctgttcggtc
    75181 gatgatgaag tgtatcaagc tactcgtcgt accattttga gctctgaaaa tccatacttc
    75241 taccaaggag aatacgcaag cggtctcggc agttctcata ccttctatcg ctatatctgg
    75301 ccaatcgccc tttctatcca aggcttgaca acaagagata aggcagagaa aaaattcttg
    75361 ctggatcagc tggttgcctg cgatggtggt acaggtgtca tgcacgaaag ctttcatgta
    75421 gatgatccga ccctctactc tcgtgaatgg ttctcctggg ctaacatgat gttctgtgag
    75481 ttggtcttgg attacttgga tattcgctaa ggggctcgct ttagctcaac cgattcttat
    75541 cagaatcaca agtttacatt taaaacgtta aaatttaaat ttagaatgag gttttacttc
    75601 atggaaaatg ttgttgtaca tattatctca catagtcact gggaccgtga gtggtacttg
    75661 ccttttgaaa gtcatcgtat gcagttggtg gaattgtttg acaatctctt tgatctcttt
    75721 gaaaatgacc ctgagttcaa gagtttccac ttggatggac aaactattgt ccttgacgac
    75781 tacttacaaa ttcgccctga aaatcgtgac aaggtccaac gctacattga cgagggcaag
    75841 cttaaaattg gtccctttta catcttgcag gatgattatt tgatctccag tgaagccaat
    75901 gtccgcaata ccttgattgg tcaacaagaa gctgccaaat ggggtaaatc aacccagatt
    75961 ggctactttc cagatacctt tggaaatatg ggacaagcgc ctcaaattct tcaaaaatca
    76021 ggcattcacg tggcgacctt tggtcgtggt gtgaagccga ttggatttga caaccaagtc
    76081 cttgaagatg agcagtttac atcccagttt tcagaaatgt actggcaggg tgtggatggt
    76141 agtcgtgttt taggtattct ctttgccaac tggtacagta acgggaatga aattccagtt
    76201 gacaaagatg aggccttgac cttctggaaa caaaaattgt cagatgtgcg tgcctacgct
    76261 tcgaccaacc aatggttgat gatgaacggc tgtgaccacc agcctgtaca gaaaaatctg
    76321 agcgaagcca ttcgtgtggc aaatgaactc ttcccggatg taatctttgt tcatagttcc
    76381 tttgatgaat atgttcaagc tgtagaaggt gcgcttcctg aacacttatc aactgttaca
    76441 ggtgagttga ccagtcagga aacagatggc tggtacacac ttgccaacac ttcttcatcc
    76501 cgcatttacc taaaacaagc cttccaagaa aatagcaacc tcctagagca agtggtagaa
    76561 cccttgacta ttatcactgg tggacacaac cacaaggacc agttgaccta tgcttggaaa
    76621 acacttttgc agaatgcgcc acatgatagt atctgtggct gtagcgtgga cgaagttcac
    76681 cgcgagatgg aaacgcgttt tgccaaggtc aaccaagtag gaaactttgt taaaagtaat
    76741 ttgctcaacg agtggaaggg taaaattgct acggataagg ctcaaagtga ctatctcttt
    76801 actgtcatta acacaggctt gcatgataag gtcgatactg tcagcacagt gattgatgtg
    76861 gcgacttgtg atttcaagga attgcaccca acagaaggct acaaaaagat ggctgctctt
    76921 atcttgccaa gttaccgtgt ggaggacttg gatggtcgtc ctgtagaggc tacaatcgaa
    76981 gacctcggag ctaattttga atacgattta ccaaaagaca agttccgcca agctcgtatt
    77041 gctcgacaag tgcgcgtgac cattccagtt cacctagcac cgctttcttg gacaaccttc
    77101 caattgctgg aaggagaaca agaacaccgt gagggtattt accaaaacgg agtgattgat
    77161 acaccattcg taacggtgag tatggatgac aacatcacag tctatgataa gacaactcac
    77221 gaagcctatg aagactttat ccgctttgaa gaccgtgggg acatcggaaa cgagtatatc
    77281 tatttccaac caaaaggaac agagccaatc tttgcagagc ttaagggcca cgaggtcttg
    77341 gaaaacacag cttgctatgc taaaatcttg ctcaaacatg aattgaccgt gcctgtcagc
    77401 gcggatgaaa agctagaaga agagcaacaa ggtatcatcg agtttatgaa gcgtgaggct
    77461 ggacggtcag aagaattgac aaacattcct ctggaaactg agttgactgt cttcgttgac
    77521 aatccacaaa tccgcttcaa gactcgcttt actaacactg ccaaggatca ccgtatccgt
    77581 ctcttggtca agactcataa cacgcgtcca agtaatgatt ctgaaagtat ctatgaggtg
    77641 gtgacacgac caaacaaacc agctgcttca tgggaaaatc ctgaaaatcc tcaacaccaa
    77701 caagcttttg tcagtctgta tgacgatgaa aaaggggtga ctgtatccaa taagggattg
    77761 aatgaatacg aaatccttgg ggataacacc attgccgtga ccattttgcg tgcatcaggt
    77821 gagctaggtg actggggcta cttcccaacg ccagaagcac aatgcttgcg ggagtttgaa
    77881 gtcgaatttg cgattgaatg ccaccaagcc caagaacgct tctcagccta tcgtcgtgcc
    77941 aaagccttgc agacaccgtt taccagcctt cagcttgcta gacaggaagg aagcgtggtt
    78001 gcgactggta gcctcttgag ccattctgtt ctcagcatac cgcaagtttg tccaacagcc
    78061 tttaaagtgg cggaaaatga agaaggctat gtcctccgtt actataatat gagtcaagaa
    78121 aatgtgcgca tatcagaaca tcaacaaacc attcttgact tacttgagcg accatatcca
    78181 gttcattcag gactattggc tccacaagag attcgtacag aattcatcaa aaaagaagaa
    78241 atttaatttc aaaaagtaaa catcaaaaga aaggaggggc gaaaaggtaa gaactaacta
    78301 ctgattcgcc cctttttatg gtaaaaacaa tgaccattgc aacgattgat atcggaggga
    78361 ctgggattaa gtttgccagt ctgactcctg atgggaaaat actggataag acaagtattt
    78421 caacgcctga aaacttggag gatttactaa cgtggctaga tcaacgcttg tcagaacagg
    78481 attacagtgg gattgctatg agcgttccag gtgcggtcaa tcaagagaca ggtgtgattg
    78541 atggcttcag tgcggtgccc tatatccatg gcttttcttg gtatgaggcg cttagctctt
    78601 atcagctacc tgtccattta gaaaatgatg ccaactgcgt tggactcagt gaactactag
    78661 ctcatccaga gcttgaaaat gcagcctgtg tcgtgattgg gacagggatt ggcggagcca
    78721 tgattatcaa tggtagactt catcgaggtc gccacggtct gggtggagaa tttggctaca
    78781 tgacaaccct tgcccctgct gaaaaactta ataactggtc gcaactagca tcaactggga
    78841 atatggtacg atacgtgatt gaaaaatctg gtcatactga ttgggacggt cgcaagattt
    78901 accaagaggc cgcagctggt aatgctcttt gtcaagaagc cattgagcgc atgaaccgca
    78961 atctgacgca aggcttgctc aatatccagt atctcatcga tccagatgtc atcagtctgg
    79021 gtggctctat cagtcaaaat ccagatttta tccaaggtgt taagaaggct gttgaagact
    79081 ttgtcgatgc ctacgaagaa tacacggtcg caccagttat ccaggcctgc acctatcacg
    79141 cagatgccaa tctctacggt gcccttgtca actggctaca ggaggaaaag caatggtaag
    79201 atttacagga cttagtccca aacaaacgca agctattgag gttttaaaag gtcacatttc
    79261 tctaccagat gtggaagtgg ctgtcactca gtctgaccaa gcctctatct ctatccaggg
    79321 tgaggaaggt cactatcaat tgacctaccg caaacctcac caactttatc gtgccttgtc
    79381 cttgttggta acagttctag cagaagctga taaagtagag attgaggaac aagcagctta
    79441 cgaagatttg gcttacatgg ttgactgttc tcgaaatgcg gtgctgaatg tggcttctgc
    79501 caagcagatg attgaggtct tggctctcat gggctactca acctttgagc tttacatgga
    79561 agacacttac cagattgaag gacagcctta ctttggctat ttccgtggag cttattcagc
    79621 agaggagttg caggaaatag aagcctatgc tcaacagttt gacatgacct ttgtaccatg
    79681 catccagacc ttggcccact tgtcggcctt tgtcaaatgg ggtgtcaagg aagtgcagga
    79741 gctccgtgat gtagagaaca ttcttctcat tggcgaagaa aaggtttatg acctgattga
    79801 tggcatgttt gccacgttgt ctaaactgaa gactcgcaag gtcaatatcg ggatggacga
    79861 agcccacttg gttggtttgg gacgctacct gattttgaac ggtgttgtgg atcgtagtct
    79921 cctcatgtgc caacacttgg agcgcgtgct ggatattgct gacaaatatg gtttccactg
    79981 ccagatgtgg agtgatatgt tcttcaaact catgtcagcg gatggccagt acgatcgtga
    80041 tgtggaaatt ccagaggaaa ctcgtgtcta cctagaccgt ctcaaagacc gtgtgactct
    80101 ggtttactgg gattattatc aggatagcga ggaaaaatac aaccgtaatt tccgcaatca
    80161 tcacaagatt agccatgacc ttgcatttgc agggggagct tggaagtgga ttggctttac
    80221 acctcacaac cattttagcc gtctagtggc tatcgaggct aataaagcct gccgtgccaa
    80281 tcagattaaa gaagtcatcg taacgggttg gggagacaat ggtggtgaaa ctgcccagtt
    80341 ctctatccta ccaagcttgc aaatctgggc agaactcagc tatcgcaatg acctagatgg
    80401 tttgtctgcg cacttcaaga ccaatactgg tctaacggtt gaggatttta tgcagattga
    80461 ccttgccaac ctcttaccag acctaccagg caatctcagc ggtatcaatc ccaaccgcta
    80521 tgttttttat caggatattc tttgtccgat tcttgatcaa cacatgacac ctgaacagga
    80581 caaaccgcac ttcgctcagg ctgctgagac gcttgctaac attaaagaaa aagctggaaa
    80641 ctatgcctat ctctttgaaa ctcaggccca gttgaatgct attttaagta gcaaagtaga
    80701 tgtgggacga cgcattcgtc aggcctacca agcggatgat aaagaaagtt tacaacaaat
    80761 cgccagacaa gaattaccag aacttagaag ccaaattgaa gacttccatg ccctctttag
    80821 tcaccaatgg ctgaaagaaa acaaggtctt tggtttggat acagttgaca tccgtatggg
    80881 cggactcttg caacgcatca aacgagcaga aagccgtatc gagttttatc tggctggtca
    80941 gcttgaccgc atcgacgagc tggaagttga aatcctacca tttactgact tctacgcaga
    81001 caaggatttc gcagcaacta cagccaacca gtggcatacc attgcgacag cgtcgacgat
    81061 ttatacgact taatactctt cgaaaatctc ttcaaaccac gtcagcttcc atctacaacc
    81121 tcaaaacagt gttttgagca gcctgcagct agcttcctag tttgctcttt gattttcatt
    81181 gagtataaaa acaagaacac cttgcttggc gcagggtgtt tcgcgtgaaa cagaagaatt
    81241 atctggtttc aaatgctaca gttagacaaa cttatgataa aatagcagaa agtgaatgtt
    81301 tcctaagagc aattctatcg atgagcaatt ggaggtatta tgctacactt aaaattagta
    81361 aaacaagaaa tagaagctga aaagccagca tctgtagaag cttggatcat ttccgtcaaa
    81421 tttaaaaaag gttgctaccg acatatatag attccaaaaa caaaaacgtt agcggaacta
    81481 gcagatgtga ttttatggag ttttgatttt gcaaatgatc atgctcacac atttttcatg
    81541 gataatgttg agtggagtca tgcagattct tactttctta gctttgttag tgacgatgtt
    81601 gaagaacgtt acacagaaaa tgtctatctg gatagcctaa gtgtcaaaca aaaatttaag
    81661 tttattttcg acttcggtga tgaatggcgt tttgaatgcc aagtgctgag agaaatcgag
    81721 acagaggacg aagaagctta tctcgtacgt tcggttggaa cgtcgccaga acaatatcca
    81781 gattatgatg gttttgacta tgaagaatgg taaaattgaa atctaaaaaa caattggaat
    81841 cagtctgtgt gtaggcttag tatttcaata gacttcctgc aaaactagaa tcctagttca
    81901 tgattgataa taccagcaat caaattcatt cgtaatccga agcgtttacg atgatttcga
    81961 taggttgttg aaaatatttt aaacgttttt actttggcaa agatgttctc aaccttgctt
    82021 ctctccttag atagcgcatg gttataggct ttatcttcag ctattagcgg cttgagtttg
    82081 ctggatttac gtggagtttg tgcttgagga tatatcttca tgggcccttg ataaccactg
    82141 tcagccaaga ttttaccagc ttgtccgata tttctgcgac tcattttgaa caacttcata
    82201 tcatgacaat agttcacagt gatatccaaa gaaacaattc tcccttgact tgtgacaatc
    82261 gcttgagcct tcatagcgtg gcatttcttt ttaccagaat cattcgctag ttcttttttt
    82321 agggcgattg atttttactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg
    82381 agttcttgaa atcgtaacac cactttgaac aagagttgct tcaacccatt ggctccgacg
    82441 gattaagttg ctttcgtgaa taccaaaatc agccgcaatt tcttcataag tgcggtattc
    82501 tcgcacatat tgaagagtgg ccataagaag gtcttctagg cttaatttag gttttcgtcc
    82561 accttttgcg tgtttaagtt gataagttgt ttttaacaca gctaacatct cttcaaaagt
    82621 ggtgcgctga acaccaacaa gacgcttaaa tcgtgcatcg gttagttgtt tacttgcttc
    82681 ataatttcgc agggagtcta ttgactcttt ggtaggtgtc aatgtttttt tcatctatcc
    82741 cgagaattat tttcccgcca tttgtatttg caaatgctga gtaggtttcc cagaaagact
    82801 ctggaagatt gtttttagct tttttgtatt ctaaatcaac cccttcaaat tttaagtcca
    82861 tatttttcct ttacatctgt tttttgtggt tctggtattt gttcaagttg agtgataata
    82921 tagcgaattg aatttcgaga gtttttactc agttaatttc ttttttaacc cactttaatt
    82981 tcttttttaa cccgggttaa aaaagaaatt aaagtgggtt aattttcctt gac
//
LOCUS       DAVMBH010000003        77621 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVMBH010000003 DAVMBH010000000
VERSION     DAVMBH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.003"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            156..1637
                     /locus_tag="VYP30_000208"
     CDS             156..1637
                     /locus_tag="VYP30_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1807270.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1999..2994
                     /locus_tag="VYP30_000209"
     CDS             1999..2994
                     /locus_tag="VYP30_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1807271.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            3122..4432
                     /locus_tag="VYP30_000210"
     CDS             3122..4432
                     /locus_tag="VYP30_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1807272.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            4528..5430
                     /locus_tag="VYP30_000211"
     CDS             4528..5430
                     /locus_tag="VYP30_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1807273.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            5432..6277
                     /locus_tag="VYP30_000212"
     CDS             5432..6277
                     /locus_tag="VYP30_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1807274.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            6287..7606
                     /locus_tag="VYP30_000213"
     CDS             6287..7606
                     /locus_tag="VYP30_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1807275.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVATKHKDNVGCIVLLGSDNLVEWQFESIFLKGREHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(7814..7886)
                     /locus_tag="VYP30_000214"
     tRNA            complement(7814..7886)
                     /locus_tag="VYP30_000214"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7851..7853),aa:Lys,seq:ctt)
     gene            complement(8150..9421)
                     /locus_tag="VYP30_000215"
     CDS             complement(8150..9421)
                     /locus_tag="VYP30_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1807276.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            9691..9930
                     /locus_tag="VYP30_000216"
     CDS             9691..9930
                     /locus_tag="VYP30_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807277.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVYSNNGLKKYEK"
     gene            10095..10274
                     /locus_tag="VYP30_000217"
     CDS             10095..10274
                     /locus_tag="VYP30_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807278.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10417..10590
                     /locus_tag="VYP30_000218"
     CDS             10417..10590
                     /locus_tag="VYP30_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1807279.1"
                     /translation="MTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGELN
                     KYTERGIGKQAGL"
     gene            10627..11079
                     /locus_tag="VYP30_000219"
     CDS             10627..11079
                     /locus_tag="VYP30_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1807280.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11370..11840
                     /locus_tag="VYP30_000220"
     CDS             11370..11840
                     /locus_tag="VYP30_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1807281.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            11859..12947
                     /locus_tag="VYP30_000221"
     CDS             11859..12947
                     /locus_tag="VYP30_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1807282.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            12928..13356
                     /locus_tag="VYP30_000222"
     CDS             12928..13356
                     /locus_tag="VYP30_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1807283.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13491..14444
                     /locus_tag="VYP30_000223"
     CDS             13491..14444
                     /locus_tag="VYP30_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1807284.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            14446..15189
                     /locus_tag="VYP30_000224"
     CDS             14446..15189
                     /locus_tag="VYP30_000224"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1807285.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15200..16996
                     /gene="pepF"
                     /locus_tag="VYP30_000225"
     CDS             15200..16996
                     /gene="pepF"
                     /locus_tag="VYP30_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1807286.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17243..17797
                     /locus_tag="VYP30_000226"
     CDS             17243..17797
                     /locus_tag="VYP30_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1807287.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTDFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            17908..18576
                     /locus_tag="VYP30_000227"
     CDS             17908..18576
                     /locus_tag="VYP30_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1807288.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(18790..18879)
                     /locus_tag="VYP30_000228"
                     /pseudo
     CDS             complement(18790..18879)
                     /locus_tag="VYP30_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(18876..19409)
                     /gene="queF"
                     /locus_tag="VYP30_000229"
     CDS             complement(18876..19409)
                     /gene="queF"
                     /locus_tag="VYP30_000229"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1807289.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(19715..20029)
                     /gene="trxA"
                     /locus_tag="VYP30_000230"
     CDS             complement(19715..20029)
                     /gene="trxA"
                     /locus_tag="VYP30_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1807290.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20046..20267)
                     /locus_tag="VYP30_000231"
     CDS             complement(20046..20267)
                     /locus_tag="VYP30_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1807291.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20366..20746)
                     /locus_tag="VYP30_000232"
     CDS             complement(20366..20746)
                     /locus_tag="VYP30_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1807292.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(20890..21843)
                     /locus_tag="VYP30_000233"
     CDS             complement(20890..21843)
                     /locus_tag="VYP30_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1807293.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIESYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(21911..23119)
                     /gene="sstT"
                     /locus_tag="VYP30_000234"
                     /pseudo
     CDS             complement(21911..23119)
                     /gene="sstT"
                     /locus_tag="VYP30_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23258..23818
                     /locus_tag="VYP30_000235"
     CDS             23258..23818
                     /locus_tag="VYP30_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1807294.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23875..24783
                     /locus_tag="VYP30_000236"
     CDS             23875..24783
                     /locus_tag="VYP30_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1807295.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            24735..25325
                     /locus_tag="VYP30_000237"
     CDS             24735..25325
                     /locus_tag="VYP30_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1807296.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25328..26434
                     /gene="yqeH"
                     /locus_tag="VYP30_000238"
     CDS             25328..26434
                     /gene="yqeH"
                     /locus_tag="VYP30_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1807297.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            26648..26959
                     /gene="yhbY"
                     /locus_tag="VYP30_000239"
     CDS             26648..26959
                     /gene="yhbY"
                     /locus_tag="VYP30_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1807298.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27011..27640
                     /locus_tag="VYP30_000240"
     CDS             27011..27640
                     /locus_tag="VYP30_000240"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1807299.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            27640..28233
                     /gene="yqeK"
                     /locus_tag="VYP30_000241"
     CDS             27640..28233
                     /gene="yqeK"
                     /locus_tag="VYP30_000241"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1807300.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28234..28734
                     /locus_tag="VYP30_000242"
     CDS             28234..28734
                     /locus_tag="VYP30_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1807301.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            28747..29100
                     /gene="rsfS"
                     /locus_tag="VYP30_000243"
     CDS             28747..29100
                     /gene="rsfS"
                     /locus_tag="VYP30_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1807302.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29203..29949
                     /locus_tag="VYP30_000244"
     CDS             29203..29949
                     /locus_tag="VYP30_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1807303.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            29959..31056
                     /locus_tag="VYP30_000245"
     CDS             29959..31056
                     /locus_tag="VYP30_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1807304.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGSVDILDRLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            31294..31548
                     /locus_tag="VYP30_000246"
     CDS             31294..31548
                     /locus_tag="VYP30_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1807305.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            31552..31806
                     /locus_tag="VYP30_000247"
     CDS             31552..31806
                     /locus_tag="VYP30_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV1807306.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            31997..33610
                     /locus_tag="VYP30_000248"
     CDS             31997..33610
                     /locus_tag="VYP30_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1807307.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            33740..34366
                     /gene="gmk"
                     /locus_tag="VYP30_000249"
     CDS             33740..34366
                     /gene="gmk"
                     /locus_tag="VYP30_000249"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1807308.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34391..34705
                     /locus_tag="VYP30_000250"
     CDS             34391..34705
                     /locus_tag="VYP30_000250"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1807309.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            34771..37167
                     /locus_tag="VYP30_000251"
     CDS             34771..37167
                     /locus_tag="VYP30_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1807310.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37180..38115
                     /locus_tag="VYP30_000252"
     CDS             37180..38115
                     /locus_tag="VYP30_000252"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1807311.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38108..39421
                     /gene="rsmB"
                     /locus_tag="VYP30_000253"
     CDS             38108..39421
                     /gene="rsmB"
                     /locus_tag="VYP30_000253"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1807312.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39436..40176
                     /locus_tag="VYP30_000254"
     CDS             39436..40176
                     /locus_tag="VYP30_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1807313.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            40173..42152
                     /gene="pknB"
                     /locus_tag="VYP30_000255"
     CDS             40173..42152
                     /gene="pknB"
                     /locus_tag="VYP30_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1807314.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42267..43025
                     /locus_tag="VYP30_000256"
     CDS             42267..43025
                     /locus_tag="VYP30_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1807315.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43027..43476
                     /locus_tag="VYP30_000257"
     CDS             43027..43476
                     /locus_tag="VYP30_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1807316.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43538..44164
                     /locus_tag="VYP30_000258"
                     /pseudo
     CDS             43538..44164
                     /locus_tag="VYP30_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            44232..44480
                     /locus_tag="VYP30_000259"
     CDS             44232..44480
                     /locus_tag="VYP30_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807317.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIDELSSN"
     gene            44611..45783
                     /locus_tag="VYP30_000260"
     CDS             44611..45783
                     /locus_tag="VYP30_000260"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1807318.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIVLYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            45783..47057
                     /locus_tag="VYP30_000261"
     CDS             45783..47057
                     /locus_tag="VYP30_000261"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1807319.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(47093..48058)
                     /locus_tag="VYP30_000262"
     CDS             complement(47093..48058)
                     /locus_tag="VYP30_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1807320.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48039..49493)
                     /locus_tag="VYP30_000263"
     CDS             complement(48039..49493)
                     /locus_tag="VYP30_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1807321.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            49869..51752
                     /locus_tag="VYP30_000264"
     CDS             49869..51752
                     /locus_tag="VYP30_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1807322.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSIPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            51901..52788
                     /locus_tag="VYP30_000265"
     CDS             51901..52788
                     /locus_tag="VYP30_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1807323.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVLQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIEFNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53108..53725)
                     /locus_tag="VYP30_000266"
     CDS             complement(53108..53725)
                     /locus_tag="VYP30_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1807324.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54140..54353)
                     /locus_tag="VYP30_000267"
                     /pseudo
     CDS             complement(54140..54353)
                     /locus_tag="VYP30_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(54838..54918)
                     /locus_tag="VYP30_000268"
                     /pseudo
     CDS             complement(54838..54918)
                     /locus_tag="VYP30_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            55034..55927
                     /locus_tag="VYP30_000269"
     CDS             55034..55927
                     /locus_tag="VYP30_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807325.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLKVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            55924..57132
                     /locus_tag="VYP30_000270"
     CDS             55924..57132
                     /locus_tag="VYP30_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807326.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHIQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSY
                     IPFISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIW
                     KTFKRALSYK"
     gene            complement(57545..58312)
                     /locus_tag="VYP30_000271"
     CDS             complement(57545..58312)
                     /locus_tag="VYP30_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807327.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(58329..59024)
                     /locus_tag="VYP30_000272"
     CDS             complement(58329..59024)
                     /locus_tag="VYP30_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807328.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(59029..59394)
                     /locus_tag="VYP30_000273"
     CDS             complement(59029..59394)
                     /locus_tag="VYP30_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1807329.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            59534..60007
                     /gene="nrdR"
                     /locus_tag="VYP30_000274"
     CDS             59534..60007
                     /gene="nrdR"
                     /locus_tag="VYP30_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1807330.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            60008..61177
                     /locus_tag="VYP30_000275"
     CDS             60008..61177
                     /locus_tag="VYP30_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1807331.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            61178..62074
                     /gene="dnaI"
                     /locus_tag="VYP30_000276"
     CDS             61178..62074
                     /gene="dnaI"
                     /locus_tag="VYP30_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1807332.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSDVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            62071..62784
                     /locus_tag="VYP30_000277"
     CDS             62071..62784
                     /locus_tag="VYP30_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1807333.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            62798..64108
                     /gene="der"
                     /locus_tag="VYP30_000278"
     CDS             62798..64108
                     /gene="der"
                     /locus_tag="VYP30_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1807334.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64199..64534
                     /locus_tag="VYP30_000279"
     CDS             64199..64534
                     /locus_tag="VYP30_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807335.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            64675..65010
                     /locus_tag="VYP30_000280"
     CDS             64675..65010
                     /locus_tag="VYP30_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807336.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMLDLRRE
                     LGKSKGGRH"
     gene            65195..65986
                     /locus_tag="VYP30_000281"
     CDS             65195..65986
                     /locus_tag="VYP30_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807337.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            65979..66620
                     /locus_tag="VYP30_000282"
     CDS             65979..66620
                     /locus_tag="VYP30_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807338.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            66624..67256
                     /locus_tag="VYP30_000283"
     CDS             66624..67256
                     /locus_tag="VYP30_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1807339.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            67284..67571
                     /locus_tag="VYP30_000284"
     CDS             67284..67571
                     /locus_tag="VYP30_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807340.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGEIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            67717..70230
                     /gene="secA"
                     /locus_tag="VYP30_000285"
     CDS             67717..70230
                     /gene="secA"
                     /locus_tag="VYP30_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1807341.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            70311..71342
                     /locus_tag="VYP30_000286"
     CDS             70311..71342
                     /locus_tag="VYP30_000286"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1807342.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            71344..72375
                     /locus_tag="VYP30_000287"
     CDS             71344..72375
                     /locus_tag="VYP30_000287"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1807343.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            72414..72782
                     /locus_tag="VYP30_000288"
     CDS             72414..72782
                     /locus_tag="VYP30_000288"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1807344.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVIASVILEENHES"
     gene            72772..73875
                     /locus_tag="VYP30_000289"
     CDS             72772..73875
                     /locus_tag="VYP30_000289"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1807345.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVNGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHIKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            73894..75909
                     /gene="recG"
                     /locus_tag="VYP30_000290"
     CDS             73894..75909
                     /gene="recG"
                     /locus_tag="VYP30_000290"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1807346.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            76225..77205
                     /locus_tag="VYP30_000291"
     CDS             76225..77205
                     /locus_tag="VYP30_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1807347.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHETMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(77527..>77621)
                     /locus_tag="VYP30_000292"
     CDS             complement(77527..>77621)
                     /locus_tag="VYP30_000292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HEV1807348.1"
                     /translation="FEVVDRTDEVSNHTYGKAKLTWFEEIFEKY"
BASE COUNT        23176 a        14500 c        17460 g        22485 t
ORIGIN      
        1 ggtaaaataa gaaaattgtt tatatattgt ctccgtagtg ttattatacg aaataaaaga
       61 ttttaggaaa agtcgttata tcatgctata cctattcttt gtggtataat tgcaagaggt
      121 ttaatccgat aatttataaa gagagaaaga tattcatgag agatttatta tctaaaaaaa
      181 gtcataggca attagaatta ttagaattat tatttgaaca taaacgttgg tttcatcgtt
      241 ctgaactagc agagttatta aattgtacag aacgtgcagt caaagatgat ctatcccatg
      301 ttaaatctgc ttttcctgac ttgatttttc attcttctac taatggtata cgcattatta
      361 ataccgatga tagtgatatt gaaatggttt accatcattt ctttaaacat tcaactcatt
      421 tttcgatttt agaattcatc ttctttaatg aaggttgtca agctgagagt atttgtaaag
      481 aattttatat cagttcatct tcgctctatc gtattattag ccaaatcaat aaagtgatta
      541 aaaggcaatt tcaatttgaa gtcagtctga cccctgttca aatcattgga aatgagagag
      601 acattcgtta cttttttgca caatattttt cagaaaaata ttatttccta gaatggccat
      661 ttgaaaattt ttcatcagag ccactatctc aattgttaga attggtttat aaggaaacaa
      721 gctttccaat gaatttgtca acgcatagaa tgctaaagtt gctcctagtt acgaacctat
      781 atagaataaa gtttggtcat tttatggaag tagataaaga ttcttttaac gaccaaagtt
      841 tggatttttt aatgcaggca gaaggaatag aaggtgttgc tcagagtttt gaatcagaat
      901 acaatatctc tttagatgaa gaagttgttt gccaattatt tgtgtcttac tttcaaaaaa
      961 tgtttttcat agatgaaagt ctctttatga aatgcgtaaa aaaggatagt tatgttgaaa
     1021 aatcttacca tctattgagt gattttattg atcagatttc agtcaagtat cagattgaaa
     1081 tggagaataa ggataatctg atttggcatc tgcataatac cgcacatctg tatcgtcaag
     1141 agttgtttac tgagtttatt ttatttgatc aaaaagggaa tacaatcagg aactttcaaa
     1201 atatttttcc aaaatttgtt tcagatataa aaaaagagct ttctcactat ttagagactc
     1261 ttgaggtttg ttctagttca atgatggtaa atcatctatc ttataccttc atcactcata
     1321 ccaaacattt ggtgattaat ttgctacaaa atcagcctaa actaaaggtt ttggttatga
     1381 gtaattttga tcagtatcat gcaaaattcg ttgcagagac actttcttat tactgtagca
     1441 ataattttga actggaggtt tggaccgaat tagaattatc aaaggaatct ttagaagatt
     1501 caccttatga tattattatt tccaatttta ttattcctcc tattgaaaat aagagactca
     1561 tctattcaaa taatataaac acggtctcac tcatatactt gttaaatgcc atgatgttta
     1621 ttcgattaga tgagtaacca aaaataacaa aaaaacgcta tttcgcgttt gaactgtacc
     1681 tcaaaagtta gacagaaaaa gtctaatttt tagggtgttt ttgttaagaa aagaccttca
     1741 atcatttaag aaaaatgtac atctagattt atagccctct aaaactcttg ctttttttgt
     1801 agaagatacg aaaaaagcca tgaaaccaag gcttttcctg ttttatgtag atgtttacac
     1861 atgaaaattg aagtattttc aaaagctaat tggagtgatt ttattcatga tgggataaat
     1921 gatctggcca aaaatgattg agaaatagtt gcttaaaaag catttgcatg atactatata
     1981 ttgaaaggag gtgataatat ggtagaacaa agaaaatcaa ttaccatgaa agatgttgct
     2041 ttagaagcag gagttagtgt tggaactgtt tcacgtgtaa ttaataaaga aaaaggcatt
     2101 aaagaagtaa ctttaaggaa agttcaaagg gctataaaaa cattggacta tatccctgat
     2161 aattatgctc gaggtatgaa aaagaataga acagaaacta tcgctttgat tattccgagc
     2221 atatggcatc catttttttc ggagtttgcc tatcatgttg agaaagagtt attaaaatat
     2281 aattataaat tatttatttg taacgctgat agcgattcac aaaatgaaat cgaatatatc
     2341 gaaatgttga aacaaaataa agtggatgga attattggta ttacatattc tgatattgac
     2401 aaatatattt tatctgattt accgtttgta agtatagata gacatttttc ggaaaatgta
     2461 tgctatgtta cttcagcaaa ttacaaagga ggacaaactg cagcagagga actggttaga
     2521 agggataata agcaccttgc ttttattggt tcaattaata tgtatgagaa tgagactata
     2581 ctcagaagta aaggattcag agaaaaagct aaggaattag gagtagatgt ctataatttt
     2641 gaaatgaaag aacctttaat aaatcctgaa gatcagataa gaattttttt gcaatctcat
     2701 aaagaaattg atggtatatt tacaataaat gatatgatgg ctctgagagt tattagtgtt
     2761 atgaaagaac tggggaaaat agcacctgat gattaccaga taattgggtt tgatggttta
     2821 aaaacttctg tcgatcaatc ttatctagtg tctacaatag ttcaagatat tggtatgatg
     2881 gcaaaagaat ctgttgcaat gatactgaaa atgattaagc gagaagagat tctagaaaaa
     2941 cgaatcgtaa ttcccacata tttttgggga gataaaacaa caaaaaaaat ttaaaaagcg
     3001 cttgacaatt aatgaaagcg ctgttataat ataatcaaca aatgaaacgt ttcaaaaaat
     3061 aggctagaag cttgtttaaa aaataaataa aaaatgaaac gtttcaaaaa ggaggaaaat
     3121 gatgcgtaaa ggtacaatgt tatctgttgt tgcggggcta tcgttagcta tacttgcagg
     3181 ttgtagtgga ggaactaact caaaacaagc gagttcttca aatgatatta aagtctgggt
     3241 acaattctct gacgaaacaa atgaaggaaa agcttggcaa aaagttgttg ataactttaa
     3301 tcaatcagga aaaagtaagt acaaggttgt aactgagtat attcctcgta gtggtagtgg
     3361 tggaggatat gaagacaagg ttaatgctgc tattacgact aatagtcttc cagatgttat
     3421 tacccttgat ggaccaaata cggcagctta tgcaaaatct aaagtaatta ctccgctaga
     3481 tgattatcta aaagataata atatggatga tgttttggac agtattaaac aacagggaac
     3541 ttataatggg aaattctatg catttggatt ttctgaatcg aatgttggtg tttattacaa
     3601 taaaaaaatg ttcaaagagg ccggaattgc ggaatcagag cttccaacgc tagaaaagcc
     3661 atggacatgg gacgaattta atacgattgc taaaaaattg aaagatcatt ataacaaacc
     3721 agcaattgat tttcgtatta attcaaacga tgaaatgttg ccatatgctt atatgccgtt
     3781 gatttggtca aataatggtt ctgtcgtaaa cgaagatgga acaaaggcag aaggatactt
     3841 caactccaaa gagagtgtag aagcagttca attcattcaa aatcttgtaa aagaaggcta
     3901 tacaactgtt agtccagtcg aaaaaggttt tgaaacagga gagtatccaa tgcttttgag
     3961 tggttcttgg acgattgctg acatgaatac aaactacaaa gatattgatt ttggtatcct
     4021 tccttaccca gtatctagta agacgaaaaa attagtatcc ccttcaggta gttggcaatt
     4081 agctgtgacg acaaaatctg ataaaaaaga ggccgcatct gaatttgtta aatttgctac
     4141 aaatacagaa tcaagtgaaa ttattagctt ggggaattcg gtccttccaa ttcgtaaatc
     4201 tacaattgaa aatatcaaag ataaagtatc cgaaccaatg cgtttcttga tggaacaaaa
     4261 ttcaaaaaca gctcatgctc gcccagttgt tgtagcatat cctcaggttt ctcgagcttt
     4321 tcaacaagca atgcaagata ttagctatta tgaagaaaat ccaaatgtgc aaaaagtctt
     4381 ggatactcgt acaaaagaaa tgcaaactgc tattgatcag tcactcaaat aatctgtaaa
     4441 aaagaaggtg gaaggaaaat gtttggaact accttcccct ttcttgttaa tagcctagtt
     4501 tgatatatat gattaaagga gatggatatg agtaaagaaa ctgttgtgga tacaaaaaga
     4561 cgtgaaaaaa taaaggataa catattaggt tatagttttt tagctccagc tttaatttta
     4621 ttaggtatct ttttagtaat tccagttgga atggtcattt attacgcttt tacagattat
     4681 tatttgttga caccagatga aagaaaattt gttggacttg aaaattttat tcgattaaca
     4741 aaagatccga ttttcttaaa gagcttcttg aatactttga aatttgttgt ttggattatt
     4801 ccagttcaat tgggagcggc cttaggaatg gctttgattg tcaataaaaa gcgaaaagga
     4861 aatatgtttt ttaaagtggc tttttttgct ccagttgtca tgtccttggt agttatttct
     4921 attctttggc tttatctttt aaatccaaat agtggcttat taaatgctat tttaaataag
     4981 gtaggtattg cttctcaacc tttcttgact agtcctaaac aagctatgta tgcaattgtt
     5041 tttgtttctg cttggcaggg tgcaggttat cagatgcttt tatttttagg aggaatgcag
     5101 aatattccac aagatgtcta tgaagctgct gaattagatg gattctcaaa atgggctcag
     5161 tttcgttata tcacgatgcc cctactaaaa ccaacagccc tgtttgtatt gttaacaact
     5221 ttaatttctg cttttaagct gattgtacaa ccaatggtta tgacgcaagg tgggccatta
     5281 aactcaacaa ttactatggt gtactatatt tatcaacaag gttttactga tcgtcttgta
     5341 ggatattcta gctcaatcgc tttagtattt acaacgttaa ttggtatgat tagcttagta
     5401 caacgtcgcg ttctgaagga ggatgactaa gatgaaacga tttaaaccaa caacaatctt
     5461 agaatatatt ctgttaactt tattggcagg actcttcctt tttcctatgg tttggatggt
     5521 agtttcagct atgaagccag aagcggatgt ttataaaaat ttgactagtt ggcaagcctt
     5581 cttaccaagt ttaaatcccg ctgattggtt taaaccttat caggaagtat ttgagcgctt
     5641 tagtattttt acatatctag ggaacagcat tttttatgct ggaacgtttg ctattggttc
     5701 tattattgtc aatgcactgg ccggtttcgc ttttgcaaaa gtcaattttt caggtaagaa
     5761 aattttattt ggtttcttac ttgctttact tattattcca gtggaaactg tgttaattcc
     5821 acaatttacc attatcaatt ccttaggttt ggtcaataat cgtcttgcag ttattattcc
     5881 aggattggcg agtgtattta atatttactt atttaggaat ttctttattg caattccaga
     5941 agagattctt gagtctgcaa agatggacgg agcaagtatc gttagaattt tctttagaat
     6001 tatgcttcca atgtctaaac ctgcagttgc tacagttggt gttttatcat ttatttcaag
     6061 ctggaatgat tatatctggc cattgatggt tttgacagat tcttctaaat tttcaatgca
     6121 ggttgcaatt acaactatta atacaactca accagtttat atcaatcagg taatggctgt
     6181 attaactatt tcaacgattc cgttgatttt ggtctatgta gtcgctcaga aatatattgt
     6241 tcaaggtctg ggtggttccg gaactggaat aaaataggat atacttatga taaataaaac
     6301 atttacagta gaaaaagcca atcgttttat agcagaaaat aaacatctcg ttaatactca
     6361 atataagcct gaagaacatt tttcagctga gattggttgg atcaatgatc caaatggatt
     6421 tgtttatttt cgtggagaat accatctctt ttatcaattc tatccatatg atagtgtttg
     6481 gggacctatg cactggggac atgctaaaag taaggacttg gtgacttggg agcacttgcc
     6541 agtggcactt gctcctgatc aagattatga ccgaaatggt tgtttctcag gctctgccat
     6601 tgtcaaggat gatcgcctct ggctcatgta cactgggcat atcgaagaaa aaaccggtgt
     6661 ccgccaagtg caaaatatgg cattttcaga cgacgggatt cactttgaaa agattgaaca
     6721 aaatccagtt gcaacaggag cagacttgcc agatgagttg attgctgctg atttccgtga
     6781 tccaaaactc tttgaaaaag atggacgcta ttactccgta gtagctacca aacacaagga
     6841 taatgtgggc tgtatcgttc tactagggtc cgataaccta gtagaatggc agttcgaatc
     6901 catcttttta aaagggagag aacaccaagg ctttatgtgg gaatgcccag attacttcga
     6961 gttagatggg aaagattgcc ttattatgtc acccatgcgt tatcagcgtg agggagactc
     7021 atatcataac atcaactcat cgcttttgtt cacgggtaag gtagattggg gagaaaaacg
     7081 ttttatccca gaatcagttc aagaaatcga tcatggccaa gacttctatg cgcctcaaac
     7141 attgttggac gatcaaaatc gtcgtatcct gattgcttgg atgcagacat gggggcgtac
     7201 ccttccaacc catgaccaag aacacaaatg ggcatgtgcc atgactttac ctagaattct
     7261 aagattggaa gatggcaaac taagacaatt ccctgttaaa aaaggccaat atcaaatcca
     7321 aatagataaa gattgtcatt accacttagg aaatgataca gattatcttg aatttggtta
     7381 tgacagtaat gcgcagcaag tttacattga tcgtagccat cttattcaaa aaattctagg
     7441 tgaagaagaa caggacacta gtcgacggta tgtagatatt gaagctaaag aattggaagt
     7501 tgttctagat aaaaattcca tcgagatttt tgtcaatcaa ggtgaagcaa gcttgactgc
     7561 aacttattac ttaacggtgc cagctgagct atcacgaatt gattaaaaat taagttattt
     7621 ctcctaaaga aaaagttctc tttctaaaat agtggaaaga ggactttttg tgttttgggt
     7681 atataagctt agtttatggt atttgtaaaa ttggtgttgg attatgattt aagctagttt
     7741 tctaaagaat ttgaaaaaaa ttttatttaa gcaaaaaaac cttggttcca aggcttttcc
     7801 tgttgtattt agatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc
     7861 tgctctgcca gctgagctaa ggaggcaaag aaaaagctgt attggtgccg aaacttcacg
     7921 gtttgtattg aacccgcgca attaagcagg tgggcaactc gctctaactg aagctgtttt
     7981 cgtgtgagac ggcctacatg ctgttagaag acttttgttt ccctaataat acaaaaaata
     8041 gtcggtcaac acttaagtgt gaagtcgtac accacagcgt ttctatactt atatgatacc
     8101 actttttcaa aaaaaatcaa gaggaaagtg caattttttg aaaaggattt cagatttttc
     8161 gcaaacgatc gatagcttcc tttctttgag ccaaagcccg ttcatattta ccagtatctt
     8221 ctgcttggaa atagtgatga ttacgaattt tttctggcag atagtcttgc ttgacccaat
     8281 ttccaggata gttgtgtgga tagagatagt cttgggcatt ccccagttcc ttgcttccac
     8341 tgtagtgccc atcacgcagg tgtcgcggaa taggcaagtg ccctgatgtt ttgaggtcag
     8401 caagtgcctt atccatagct acataggctg agttggattt tggagaaagg gccaaatcaa
     8461 tcacgacatt ggcaatgaga atgcgggctt cggggaaacc aatcctttgt gcagcatcca
     8521 gagcagtcac ggtatgaatc tgggcctcag gattggctaa gccgatatct tcataggcga
     8581 taacagtcaa gcgacgagcg agactaggca gatccccagc ctcaatcaag cgggcagtat
     8641 agtggagact ggcatccaca tctgagccac gaatagactt ttgcagggca gatagaacat
     8701 catagtgacc gtctccatcc ttgtccatag tgatgtagct tctctgaaga ctattttcca
     8761 tgatgtctaa ggtgatgtgg cgaatgccct cgtcattctc aggggtagat agaacagcca
     8821 agtccagtga gttaaaggca gagcgaaggt ctccgtttgt agaggttgcg atgaaatcca
     8881 gcgcatcctc atctagttct attggaaaat caaaaccacg ttcagggtta cttagagcta
     8941 tctgcagggc ctctttgacg tcttggttag acagaggttc caactcgaaa atttgaactc
     9001 ggctacgaat ggcaggagtg acagagaaga aaggattttc agtcgttgct ccaatcatga
     9061 tgaccagtcc actttccaag agaggcaaga ggaagtcttg cttggtctta tctagtcgat
     9121 gaatttcgtc tagcaatagg acgagaccac cagaaaattt agcttcttcc gagatttctt
     9181 gcagtcgctt tttactatca actgtcgcat tgaaagttcg aaaggcatac ttggtcgttc
     9241 cagcgatggc agaggcaata ctggttttgc cgattccagg agggccatat agaatcatgg
     9301 aggacaggcg gttggcttcc accatgcggc ggatgatttt tccaggtccg accagatgct
     9361 cctgaccgat gacctggtcg atggttttag ggcgcatgcg aagcgcgaga ttgtctggca
     9421 tagcagtcct ttctaacgtg gatttgagta gaatgactca tctactatat cttactatgt
     9481 ccattctagc ctattagttg tgatatttca atggttttgt aataatcagg gagtgagata
     9541 gaatcttttt tactatttaa tttaatgagg agaggtatca gcatgagaga tttgattttc
     9601 cttaaagctc aaaataggat agttgagcct aaagaagtgg aagtgctgac ttgagaaata
     9661 atattgctga atgtcattgt atgaactata atgaaaagag aggtgataag caatggaaat
     9721 gatggaccaa gtcaggaaat tttgattttt acaaaacaaa ttcgtcattg gattcttagt
     9781 gatcaagtta tttcagggaa aagaaaactt ttcttccggg aagatactcc aaaagagatt
     9841 ttagatttgt acgaaaacat taaatctaaa cttgattttg cttaccaaga agtttattct
     9901 aataatgggt tgaaaaaata tgaaaaatag aataattgat gtttttgaag tagtaaatcg
     9961 catccttgta ataactgttg aaaatcctaa tttcgaagac ttgagagtta atcatactca
    10021 atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt acggtaaggc
    10081 gacgttgacg tggtttgaat ttgattttcg aagagtatca gtttgtaaaa attggagata
    10141 aaaaatatag agtacgcagt ggtcctatga ttcattcaac tccgcctcaa tctgtcttag
    10201 atcgagatac ttttacaatt gactatacag atgatgaatt gctcgataaa gaagcagttt
    10261 ttactactca ttagaaaaat aggtctgaat aaattggttt cccttagaac cacatctagg
    10321 ggcttttatg tataatagaa taataagtat cactccttta caatacgtgt aacacgtgtt
    10381 ataatggtgt tgtcaggagg taaaagcgct atacctatga cacaaaaaga gatggttaaa
    10441 ctccttacgg cccatggttg gataaagact agaggcggta aaggctccca tattaaaatg
    10501 gagaagcaag gggaaagacc tatcacaatc cttcatggtg agctgaataa gtacactgaa
    10561 agagggatag gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt
    10621 agtgaaatgt tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa
    10681 gcgacttatt ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt
    10741 tctgaggctt tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag
    10801 agtgatggag agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat
    10861 ccttttaaag atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct
    10921 atggtatctg ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg
    10981 accataccaa aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact
    11041 ttgacagacg ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt
    11101 aatagtcaat aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat
    11161 ttattagccc tttcgcgggc tttttatatt gatttttatg agaaatgaag aaatcagact
    11221 tttaagaaaa tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata
    11281 aaataatttt gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg
    11341 attaaagagt cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag
    11401 aggaagagtt ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc
    11461 atgcggtaga agtgagtttt ctattggaag cacaaaatgc tgcaggtgtg gagatggtgg
    11521 atgaagacgg agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca
    11581 atcctgctaa gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta
    11641 aaaaaggatt ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg
    11701 aagttgggct agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta
    11761 tggaatggaa tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt
    11821 atccttatcc aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt
    11881 tggtttatgt gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat
    11941 ttgcagagtt ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc
    12001 taagcatgta tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga
    12061 caggctatcg gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca
    12121 ggtttcatct tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa
    12181 aagaggatga aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc
    12241 tcggcttgat attattggcg atagtgtttg gatttttgac aagaagctgg tattttgcag
    12301 ggacttggat ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca
    12361 ccgatggagc aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc
    12421 tggtattgag acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact
    12481 ttgttcaagc agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc
    12541 aaggtgaagt ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat
    12601 tacttgagag gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata
    12661 tcgccttgtt ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca
    12721 aatcgtttct gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa
    12781 aggtgaagaa agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg
    12841 atagtagtcg aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg
    12901 aaaaggaaat gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc
    12961 aagattgccc tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat
    13021 atcccttgtc ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct
    13081 tttgaatgcg ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt
    13141 ctgctttgga gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg
    13201 gttggtcagc taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc
    13261 tatcagctga tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa
    13321 gagagattaa aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct
    13381 aaactgaacc cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc
    13441 ttcagagaat ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa
    13501 catggcaaga gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct
    13561 tgattgagct gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg
    13621 ttgaccgctt cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag
    13681 cctactaccc tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat
    13741 cagaattgac ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg
    13801 aggaagactg ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt
    13861 tgaccatcgt tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc
    13921 tggatcctgg catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg
    13981 ccttggaaca ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg
    14041 ttctctctat tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg
    14101 atgtggcagt tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc
    14161 atgtagcggc aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa
    14221 acatcttggc ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg
    14281 aaggttacct gataatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg
    14341 ctgaatcagc tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg
    14401 tctttaagaa aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt
    14461 gtaaaaggca gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg
    14521 tttcaggtta tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc
    14581 aagcgcttgg cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta
    14641 aatgacaatg tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac
    14701 aagctggagt tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt
    14761 cctgcagact ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa
    14821 ctagaaaaaa ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt
    14881 aaacttttcg agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata
    14941 gtagcctatg aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact
    15001 ggtcttgaaa caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct
    15061 gcagaaatcg aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt
    15121 ttgcgagcag aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta
    15181 gagaaataag aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact
    15241 ctgggactta acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc
    15301 tcgtgaagac atcaaccaat ttagccgtga ctacaagggt aatcttcata cttttgagga
    15361 tttcgagaag gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa
    15421 ctatgctttt atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca
    15481 agctgggatg gaatttgaaa cagatgccag cgtagccttg accttctttg acgatgcctt
    15541 ggtggtagca gacgaggaag tcttggaccg tttgggtgaa ttgcctcact tgacggcagc
    15601 tattcgtcag gccaaaatca aaaaagccca ctatctaggg gctgatgtgg agaaggcctt
    15661 gaccaatctc ggtgaagttt tctacagtcc gcaggacatt tatactaaga tgcgagctgg
    15721 ggattttgaa atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac
    15781 ctatgagaat ttctaccaaa accatgagga tgctgaggtt cgtgagaaat ccttccgttc
    15841 cttctcagag ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt
    15901 caagtctgaa aaactcttgg ctgatatgaa gggatacgac tctgtatttg attatcttct
    15961 agctgaacaa gaagtggacc gtgtcatgtt tgaccgccag attgacctca tcatgaagga
    16021 ctttgcacca gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa
    16081 gatgaccttt gcagactgga aattggactt ggacagcgcc ctgaatcctg aagtgactat
    16141 tgacgatgcc tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca
    16201 ggaagttgct cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga
    16261 ttccggtggt tatgcggcgg acccatatcg cgtacaccct tatgtactca tgagctggac
    16321 aggccgtttg agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat
    16381 cttttcagac aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc
    16441 accgtcaacc ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc
    16501 acgtcaaaaa cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat
    16561 cacccacctc ttggaagccg ccttccagcg taaggtgtat acattgattg aagaagggga
    16621 gacctttgga gcaagcaagc tcaacagcat tatgaaggaa gttttgacag atttttgggg
    16681 cgatgccatt gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta
    16741 tatgggcttg tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct
    16801 tcatcttaaa aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg
    16861 tagcaagaca ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc
    16921 actccgtgat accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc
    16981 tgagttgggg gagtaagggg aatagaaaaa ttttctagaa tgatgtttat gggcttgtta
    17041 agcgtcattc tatttgtctt agttgtagct attttcaaaa atgttgttga aggtcgtgat
    17101 gttaaatttg aacttactgt agaactggta ttgatagtta tttacgtcat tttatatcag
    17161 attgtattta attgagaatt caatattgag tcatttaaga ctgccttttt gaacagttgc
    17221 tagaaatgta gaggtattga ccatgtatca agatttacta agaaaaatag cagaagaaaa
    17281 accaaattat aaccaggaag aaatccagtg gttgtttgat catttgggaa atccttctcc
    17341 agaaattcgt gatgaccttt caaatcaagg cttgcactat ctttcaaaag aaaaggatac
    17401 aacagatttc tcaagtcagt atggttgggt tcatgctttt gcacatggag ccgatttact
    17461 gacagaggtg gtttgtcatc cagactttcc tataaacaga attcatgaag tatttgacat
    17521 acttggccaa ctatttaaaa gaatgtcgat tcgctttaca gatgatgagg attggcgttt
    17581 agcaagagtg atctatgaac ctattttaca agggaagttg gagcaagaac aagtagcttc
    17641 ttggataaaa actgttgatt ttccgataga agaaagggag gatttttaca aattttccaa
    17701 ctttagatcc tgtctggtgg aagtctatgt ccaacttgac cagagaaata gtttacaaga
    17761 tgacctgaaa gaagctatcc agtcttttca atactagaga ttagctaata gttctatgat
    17821 tttcaaaaaa tttccaatca attttcttga aaccctttcc tacttttgat agactagtat
    17881 ctagtttttg aaaaaaggag aaagaaaatg aaaaaatttg ttgctgagtt aatcggtacg
    17941 ttcatgcttg tgttcgttgg gacaggagct gttgtttttg gaaatggtct tgatggcctt
    18001 ggtcaccttg gaatcgcctt tgcctttggt ttggcaatcg tggtggcagc ctactcaatc
    18061 ggaactgttt caggtgctca cttgaacccg gctgtttcga ttgctatgtt tgtaaacaaa
    18121 cgtttgtcat cttcagaact tgtaaactac atccttggtc aggttgttgg agctttcatc
    18181 gcttctggcg cagtcttctt cctcttgggt aattcaggta tgtcaactgc tagtcttggt
    18241 gaaaatgcct tggcaaacgg tgtcactgtc tttggtggtt tcttgtttga agtcatcgca
    18301 actttcttgt ttgtcttggt tatcatgact gtgacttcag aaagcaaggg caatggcgcg
    18361 attgctggtt tggtaatcgg tttgtcattg atggcgatga ttcttgtcgg attgaagatt
    18421 actggacttt cagtaaaccc agctcgtagc ttggcaccag ctgtcttggt aggcggcgca
    18481 gcccttcaac aagtttggat tttcatcctt gcaccaatcg ctggtggagt tcttgcagcc
    18541 cttgttgcaa aaaatttcct tggaacagaa gaataattga aactcaaaaa gccttgctcc
    18601 tcatcttgag gaacagggct ttttcgtatg atactcttcg aaaatctctt caaaccacgt
    18661 cagcttcacc ttgccgtagg tatggttact gacttcgtca gttctatcca caacctcaaa
    18721 acagtgtttt aagctgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct
    18781 gacttcgtca gtttcatcta caacttcaaa acactgcttt gagcaacctg cggctaactt
    18841 cctagtttgc tctttgattt tcattgagta tgagtttagc ggttgtcaat tttctctgga
    18901 taaaggtcgt gttggaagag gcgttgttct gccaagccct catacttagt tccttgctta
    18961 ccgtagttgt agtaggggtc gattgaaatg ccaccgcgcg gagtgaattt tccccagact
    19021 tctaaatagc gagggtctag caagttgacc aagtctttcc cgatggtgtt gatacagttt
    19081 tcgtggaaat ctccgtgatt tcggtagcta aatagatata gtttgaggga ttttgactcg
    19141 acacagagct tgtcaggaat gtaggaaata tgaatcgtcg caaagtctgg ttgagcagtg
    19201 atttgtccca gcagagacat atcgaggata tggtgacgaa tgccctgttc cttagcgatt
    19261 tctctagcaa tttgaatttc gaggtgatga cgttggccgt aggcaaaggt gacagcttcg
    19321 actgtttcat agtgttgcat ggtccagaaa aggcaggttg ttgaatcttg accgccacta
    19381 aagacgacca aggctgattg acgtttcata gtactccttc caaaatggga aatgttcaga
    19441 gcacgcaaaa agctcccatt agggagctaa aaaataccaa atcgaggttt ttttagcgat
    19501 ggcatatccc aaacatcgta atattctact tatatagtaa aatgaaataa gaacaggaca
    19561 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt
    19621 ctagtttcaa tatactatag tctagcatat tttttgaaaa atggcaaagg gcaagaaaaa
    19681 agagaccaaa gaaagtactt ggtctctcgt ttgattagct caattcagca atgatggcct
    19741 tgatttgttc tgctgtgtga acacctgcaa cctgtttgac aacttggccg tcttttttga
    19801 agagaagagt tggaatagac atgattccaa aagcacgagc tgtgtttgga ttttcatcaa
    19861 cgtccatttt aacgattttc aagacatctt ctgaaagttc ttcagacaat ttgtccaaga
    19921 ttggaccttg catacgacat ggaccacacc aagttgccca gaagtctact aagaccaaac
    19981 cgtcttttgt ttcttgttcg aatgttgcat ctgtaattgc ttttgccatt gtatttctcc
    20041 tttttttagt tatattggct taaatcttgt ttcatgagat agaagaagat atctccataa
    20101 gtcccatggt agtccaaatt atgacccttg taagttaatt tttggacagg gtagtagtct
    20161 gcgacgccga taaggcaagc ttgttgcgaa cgttcaaagt cttcataaga ctcgaaagtc
    20221 acagttcttt cgttcttgct ggcatctata taggtaattt caatcatatt taaaactcct
    20281 ttgtttaatg ctaactttat tttactcctt ataaaagaga atgtcaagaa aaatgattgc
    20341 gcacgcaact ttttttaaaa tcatcttaaa tcaagaaatc caaacctgct tccaagcttt
    20401 cttcgacagt cttttgtagc gaggccagtg tcttttgccc atcatttgtc aggcagataa
    20461 aactagagcg tctatcttga tggcaacaca tgcgactgag tagaccgcaa tttttagctt
    20521 ccaagcgagc caccatccta gaaactgcgc tcgggctcag atgaagctta tctggcaggt
    20581 caatctggcg tagagatttt tcttcagcca agtccagata gtagagcagg tagaactctt
    20641 tcaaggtcag actttgctcg ctctgttggg caatggtctc ttccaagaga ctttcaattt
    20701 ctttctgacg ccgattgaag tcaaaccatt tttccaaata ggtcatagtg tctcctttct
    20761 ttttagagtc ataaaataga agaaagtcca ttaacgggca gtctctgcgt cacaagatga
    20821 ttgcgcatgc aataattata ctacttttca agaatgctgg caagctctgt tttttagtgg
    20881 ttttattttt tactgtccat atttttggta aaaatcaact tttacttgga tgaaggtttt
    20941 ggcttcacgt aggagttgaa gaagggtggc gcgggtttca aactcttctc ttgtcttggg
    21001 cagactgcgg ttccggaaga cttccagata actttcaatt tcatctagca aatcagaagc
    21061 aggattggtc tggctcagtt gaccagcaat ttttgaaaag agctgcgcta aaatcaggct
    21121 ttcactggcg gcaaggtgac aagtgttaat ctgttgggcc atgtttctca ggatacgact
    21181 ttgtcgttgt ctcatctcaa agtagtggat atggtagtcg gtctggtgaa agaggtggtc
    21241 agagtgatcc aaatagacca gtctgagggc ttctttcaaa agcgtgtcta attctgctac
    21301 cagctgtgct cggttgcgtc cgtctcctct ggataaatag tatttgaagc gctggaggat
    21361 atcttttaac ttttcttcca ccagcgtgtg gtagtgctgg atttcctctt ctcgtgaagg
    21421 catatagaga ttaacaagca aggcaaatcc tgtaccaata gcaaagagaa ggaattcatt
    21481 gactagaagg tctggagagg ttgactcttg aaccaagaga tggctaacca aaacagtgct
    21541 tggtgtgatg ccaatttccc agcccatctt gtaggctaaa ggaacgtaga aggccagata
    21601 gaggccgaga ctccagatat gaaatccgct caagtgaaaa gctagaacac cgatagccag
    21661 agctagaagc atagaaaaaa gacgattgcg agccagtttt aaagtacttc tacgcgtatc
    21721 agataggctc aagagagcga taattccagc cgaaactgct gacgaaagat tgagaaaata
    21781 agcaagcagg caggcaagac aggtagctaa gatgagcttg gtcgtacgtt ggctaataga
    21841 cataagaatt tcctaataag ttagaataaa agcgtaaaag acaagacatg agcaggcttg
    21901 ccttgatgag ttatttttta cgggttgctg cgtattcggc aacggcggta aagaggacat
    21961 ctgtagaaga gttaagggct gtttcacatg agtcttggat gacaccaatc acaaaaccaa
    22021 ccccaacaat ttgtatggca atatcgttag aaataccgaa aaggctacaa gcaactggga
    22081 taagaaggag ggaacctccg gcaatacctg aagcatcaca ggctgagata gctgctacca
    22141 cactgaggac aaaggctgtg gcaaagtcaa caggaattcc aagagtgtta actgtaacaa
    22201 gggtcaaaac gttaatggta atcgctactc cagccatatt gatagtagaa ccgagtggga
    22261 tagaaacaga ataggtatct gggttgagtc caaggtcatg gcagagtttc atgttgacag
    22321 gaatgttagt cgcagaacta cgagtgaaaa aggctgtcac accgctgaca cggaggcagt
    22381 tccaaactag agggtaagga ttgcgtctca taaagaagaa ggcaatcaaa gggttgacca
    22441 caggggcaac aaaaagcata gtcgttacta atagaaccaa taaaataccg tagttggcaa
    22501 ggcttccgac tcccttgtca gaaatggttt taaaaacaag accaaggatt ccaaatggag
    22561 ccagattgat gatccattcg acaattttag aagtcacgtc agcgatagtt tttagcaatt
    22621 ctttactatt tttactggct tctctcatag cgattccaaa aatgactgcc caagataaga
    22681 ttctaatata gttagcagta agcagggcgt tgactgggtt gtcaaccagt ttgagcaaga
    22741 ggttgctgag gacctgccca atcccatctg gtggtgcaat ttcagtattg gcactattta
    22801 gggtaatttc aatagggacg atgaaacttg ctagtacagc tacaagagca gcggcgaaag
    22861 tccctatcat aggatataca agaaaacaac agttttcata ttgctatctt gtcccttttg
    22921 atgttggaaa gggcattggc aacgagggca aagactagga taggagcaac agcttttaga
    22981 cctccaacga ataaatcccc gagtagccca atccctgaga gattaggaag ggtcagtcct
    23041 aggattcccc acaaagcata ccaatcaaga tacgcttgac aaggcttgcc ttattccaag
    23101 catgaatgat tcttttcata ataatctcct ttttgtgtag tgattatgat tatagtataa
    23161 atgatagaca aaatcaagaa ttttctgtct attttttgaa tatttatgga gaatgagact
    23221 gatgaaaata tggtataatg aaataaagga gttttatatg caaaaattta ttcaggctta
    23281 tattgaaaag ctagatgtga caaccattat cgagaatatt ctaaccaagg tcatttctct
    23341 tttactgctt ttgattgtat tttatattgc taaaaaaatg cttcatacca tggtgcagag
    23401 aattgtcaaa ccttctctaa aaatgtctcg tcatgatgtc ggacgccaaa aaaccatctc
    23461 acgtttacta gaaaatgtgt ttaattatac gctatatttc tttttactct actgcatttt
    23521 gtcgatttta ggtttgccag tttctagttt gctggctgga gctggtattg ctggggtagc
    23581 gattggtatg ggagcccaag gctttctgtc tgatgtcatc aatggctttt tcatcctctt
    23641 tgaacgtcaa ctggatgtgg gagatgaggt cgttctgaca aatggaccga ttactgtatc
    23701 gggtaaggtt gtcagtgtgg gaattcgtac gacacagctt cgtagcgagg agcaagccct
    23761 tcactttgtc cctaaccgaa atatcacagt tgttagcaat ttctcacgca cagactagac
    23821 ctgttatttt aagtaatttg tggtacaata gagggagttt aataaggaga aaagatggtt
    23881 ttagaaaagc agttgggcaa tggttgtacc tggatagacc tagacctagg aaagttgaat
    23941 aaactagaag acctttctga aatttacggt ttggacaagg aaaccattga atacgcactg
    24001 gatagaaacg agcgcgccca catggattac caccgtgaaa gtgggacggt tacctttatc
    24061 tataatgtcc tagacgtaaa aaaggacaag gcctactatg agacttttcc catgaccttt
    24121 attgtcgagc atcgtcgcct gattaccatt agtaatacca agaacgccta tgtcattgaa
    24181 cagatgactc gttatctgga gagccatgac acgctttcga tttataagtt tctctttgcc
    24241 agtctggaaa ttatcagcaa tgcctactat cctgtcattg agcagatgga caagagtagg
    24301 gatgaggtca atgacctctt gcgccagcga actaccaaga aaaacctctt tgccctgtct
    24361 gatttggaga ctggtatggt ttatctgacg gcagctgcca aacaaaatcg gattttgtta
    24421 gagcatattc aaggtcatgc cttgtatcgt agttttgatg agattgagag agaacagttt
    24481 gatgatgcca tgattgaggc tcatcagctg gtatccatga cagacctaat ctctcagatt
    24541 ttacagcagc tttcagcctc ttacaacaat attctaaaca ataatctgaa tgacaatttg
    24601 acaaccttga ctatcatttc agtcttgcta gctgttttgg cagtcgtgac aggctttttc
    24661 ggaatgaatg ttcccttacc tttaacagat gagccccatg cttggctcta tatcagtttg
    24721 gctagtgcag gtttgtggat tgttttatcc ttgttactaa ggaaaattgc gaaaaaaagt
    24781 taagaaaagg agccagaatg gcgattgaaa attatatacc agattttgct gtggaagcag
    24841 tctatgatct gacagtccca agcctgcagg cgcagggaat caaggctgtt ttggtcgatt
    24901 tggataatac cctcattgct tggaacaacc ctgatggaac gccagagatg aagcaatggc
    24961 tacatgacct tcgggacgcg ggtattggca ttatcgtagt gtcaaataac accaaaaaac
    25021 gcgttcaacg agcagttgag aaatttggga ttgattacgt ttactgggcc ttgaagccct
    25081 tcacatttgg tattgaccgt gctatgaagg aattccacta tgacaaaaag gaagtggtca
    25141 tggttggcga ccagctcatg acagatatac gagcagccca ccgtgcaggg attcggtcaa
    25201 ttttagtcaa acccttggtc caacatgact caatcaaaac gcagattaac cgaactcgtg
    25261 agcgtcgtgt tatgagaaaa atcactgaaa agtacggacc gattacatat aaaaaaggaa
    25321 tttaactatg gaagaaattc tctgtattgg ttgtggagca accattcaga cgacagataa
    25381 agctggtctt ggttttaccc cccagtcggc acttgaaaaa ggtttggaga ctggcgaagt
    25441 ctattgccaa cgctgtttcc gtctccgcca ctacaatgaa atcacagatg tccagttgac
    25501 gaacgatgat ttcctcaagc tcttgcacga ggtgggagac agtgatgcct tagtggtcaa
    25561 tgtcattgat atctttgatt ttaatggatc tgtcatccca ggtttaccac gtttcgtctc
    25621 gggcaatgat gtcctcttgg taggaaataa aaaagatatc cttcctaagt cagttaagtc
    25681 tggtaagatt agccagtggc tcatgaaacg tgcccatgaa gaaggtcttc gtccagtcga
    25741 tgtggtccta acttcagcac aaaataaaca tgccattaag gaagtcattg acaagattga
    25801 acactaccgt aagggccgcg atgtctatgt ggtcggtgtg accaacgttg gaaaatcaac
    25861 tctaatcaat gctattatcc aagaaatcac gggtgatcag aatgtcatca ctacttcacg
    25921 cttcccaggt acaaccttgg acaaaataga gattccgctt gacgacggat cttatattta
    25981 cgatacgccg ggaattatcc accgccacca gatggctcac tacttgacgg ccaaaaacct
    26041 caagtatgtc agtcctaaaa aggaaatcaa gcctaagacc tatcagctta atcctgagca
    26101 aaccctattt ttaggtggtt tgggacgctt tgactttata gcaggagaaa agcaaggatt
    26161 tactgctttc tttgataatg aactcaaact ccatcgtagc aagcttgaag gagctagtgc
    26221 tttctacgat aagcacctgg gaactcttct gacaccacca aatagcaagg aaaaagaaga
    26281 tttcccaagg ctagtccagc atgtctttac cattaaagat aagacagacc tagtcatctc
    26341 aggcctaggc tggattcgtg taacaggcat agcaaaagtc gccgtctggg caccagaagg
    26401 cgtcgccgtc gtcacacgaa aagcaattat ttaaaacaaa atcgctgagc gaacaaagtg
    26461 agctcatata gcgatagtta ttgccgtggt gtgattgcca atctgtagat tggcaagggg
    26521 cacaattgag accaaggctc aattgtgagg tcaggaaatc catttttcaa agatgaaatc
    26581 tttggaaaat tagttccgac cgtccctcac cacctaaaat aactatcaaa aaacaaggaa
    26641 gaaaattatg tcattaacat caaaacaacg tgccttcctc aacagccagg cacacaccct
    26701 caaacctatc atccaaatcg ggaaaaatgg actcaacgac caaatcaaaa ccagcgtccg
    26761 tcaagctctt gatgcgcgtg aattaatcaa ggttactctc ttacaaaaca cagatgaaaa
    26821 catccacgaa gtagctgaaa ttttggaaga agaaatcggt gtggatacag tccaaaaaat
    26881 aggacgcatc ttgattttgt ttaagcaatc tagcaagaaa gaaaatcgca agatttctaa
    26941 gaaagtcaaa gaaatctaag accgaaactc caaataactg tttttataga gaaataaagg
    27001 ggactagcct atgacaatcg aactattgac tccctttacc aaggtagagt tggagccaga
    27061 aatcaaggag aaaaaacgca aacaagttgg gattttaggg gggaatttta accctgttca
    27121 caatgcccat ctcattgttg cggatcaagt acggcaacag ttgggactgg atcaagttct
    27181 tctcatgcct gaataccaac ctcctcacgt tgataaaaag gaaaccatcc ctgaacacca
    27241 tcgtctcaag atgcttgagt tggcaattga gggaattgac ggcctagtca ttgaaaccat
    27301 tgagttggag cgcaagggta tttcctacac ctacgacacc atgaagattt tgacagagaa
    27361 gaatccagat acggattatt actttatcat cggtgccgac atggttgact atctgcctaa
    27421 gtggtaccga attgatgaac tggttgacat ggttcagttt gtgggggttc agcgtccacg
    27481 ctacaaggta gggacttcct atccagttat ctgggtggac gtaccgctca tggatatctc
    27541 gtccagcatg gtgcgggact tccttgccca aggtcggaaa cccaactttc tcctacctca
    27601 gccagtgcta gactacatcg agaaggaggg gctctactga tgtcctatca agactatatc
    27661 aactgctccc gtgaggcctt gttggaaaaa atggcagagt ttctacctga gaaacgtcta
    27721 acccattgtc taggtgtgga gcgtgccgct atggaattag ctcagcgctt tggtgtagat
    27781 gttgagaaag caagtctagc aggtcttctt catgactatg ctaaaaagtt gtcaaatcag
    27841 gaatttctag ccttgattga ccgttaccag ctagaccctg acctcaaaaa ctggggcaat
    27901 aatgtctggc atggtatggt cggaatttac aaaattcagg aagatttgga tttgcatgat
    27961 tcagaaatcc tgcgagccat tgaagtccat acagtcggtg ctggtcaaat gacagaccta
    28021 gataaggtca tctacgtcgc agactatatc gagcacaatc gagcctttcc tggagtagat
    28081 gtggcgcgtg agattgcaaa tctatcgctc aataaggcgg tggcctacga aacagctcgt
    28141 accgtggagt atctagctca tcagggattc cccatctatc cccaaaccct tgaaacctat
    28201 aacgcctttg tgcactattt gaaagagaac taaatgaaga cggcttttat aatcattgat
    28261 gttcagaatg ttttagtaga aactgggttc cagacaaaaa gtctattggg aaaaatttct
    28321 tatttacaaa accaggctag aagcaagaat attgaaatta tctatgttca acatattgag
    28381 aactctgaag ctcaaacatc agaagattgg cagttatctg cgcttttaaa tcgaaaacct
    28441 gctgaaaagg tctttcagaa gaagtataac agtattttca aagaaactgg cttaaaagaa
    28501 tacttggata agcaggggat tgaaaaatta gttttatgtg gtatgcagac agaatattgt
    28561 gtggatacct ctgtcaaggt tgcctttgaa tatggctatc agcttattgt tccagaaggt
    28621 gctgtcacaa cctttgatgg ggatgacatt ccagcagaaa cgattaatga attttatgag
    28681 gacatttggg aggagcgctt tgcagatgtt ctagattaca aacatatttt ctaaaaagag
    28741 gattaaatga acgaaaaaga attactagaa ctagtcgtga aagcggctga tgagaaacgt
    28801 gcggaggata tcctcgcact tgatgtacaa gatttgacta gtgtgacgga ctactttgtc
    28861 atcactagct caatgaatag ccgtcagttg gacgctatcg cagctaatat ccgtgaaaaa
    28921 gtagctcaag caggctttaa aggtagccat gtcgaaggcg atgcagctgg aggctgggtc
    28981 ttactggacc ttggtgctgt tgtcgtgcat atcttttcag aagaaatgcg tgcccattat
    29041 aatctagaga agctatggca tgaggcgaat tcagtagata tttcagaagc tcttgcttag
    29101 aagatgaact cagttgtagt caactgggtt tctttgctta ttttagaaaa attgatagaa
    29161 aggtaaaggg ctagtggtgt ttaccatgga gctcttagta tcatgattat ggcgacttat
    29221 gaaacctttg cggcggtcta tgatgcggtc atggacgata gtttatacga caaatggacg
    29281 aatttttctc tgcgtcattt gcctaagacc aaggagagaa agaaactctt ggaattggct
    29341 tgtgggacag gaattcaatc agtgcgcttt tctcaggctg gttttgatgt gactggactt
    29401 gacttgagtg cggatatgtt gaagattgcg gagaagagag caacttcagc caagcaaaag
    29461 attgctttta tagaaggtaa tatgctgaat ttgtccaagg cagggaaata cgattttgtc
    29521 acgtgttatt cggactctat ctgctatatg caggatgagg tggaagtagg ggacgtcttt
    29581 aaggacgtgt acaatgcgct gaatgaagag ggagttttca tctttgacgt gcactcgacc
    29641 taccagacag atgaagtatt ccctggctat tcctaccatg aaaatgcgga agattttgcc
    29701 atgctttggg atacatatga ggacgaagtt cctcactcca tcgtgcatga gctgactttc
    29761 tttatcaagg aggctgacgg ttcctttagt cgccacgatg aagtacatga ggagaggacc
    29821 tatgagatct tgacctatga tatcttgctg gaacaggctg gatttaagtc cttcaaactc
    29881 tatgcagact ttgaggataa ggagccaaca gaaactagca cccgttggtt ttttgtggcg
    29941 cagaagtagg agattagcat gaccatcaca ggtattatcg cggagttcaa tccttttcat
    30001 aatggccata aatacctgct ggatcaggca gagggactga aaattgttgc catgtcaggg
    30061 aatttcatgc agcgtggaga gcctgctatt gtggataagt ggacaagggc ccagatggcg
    30121 ctggaaaatg gcgcagactt ggtagtggaa ttgccctttt tagtcagtgt tcaggcggca
    30181 gattttttcg gtcaaggatc tgtggatatc ttggatcgct tgggcataga tagcctcgct
    30241 tttgggacag aagaagttct agattatcaa aaaatcgctg acttatacac agagaaaggt
    30301 gctgagatgg agaaatttgt gaaaaatctg cctgattccc tttcctatcc ccagaaaacc
    30361 caagctatgt ggaaggaatt tgctggtctt gatttttcag gtaatacccc caatcatgtt
    30421 cttgctctgg cctatgccaa ggcggttgca ggacggaata tcaagctgca tccgattcag
    30481 cgtcaggggg caggttacca ttctgtgaat aaagatgtgg actttgcctc ggcgacagcc
    30541 ctccgtcaac atcagaagga ccaagatttc ttagaacgtt ttatgccttc tgttgcccta
    30601 tttgagcagg ccagtaaggt gatctgggaa gactattttc ccttgctccg ctatcaaatc
    30661 ttgtcaaatc ccgacctaac caccatctat caggtcaatc aagaaatggc tgtgcgcatt
    30721 aaagaagcta ttaaaacagc ccagtctgtg gaagaattgg tcgagttagt gactaccaaa
    30781 cgttacacca aggcgcgtgt cagacgccta ttgacctata ttttgatgca ggctagagaa
    30841 agtgacttgc cagaagccat tcatgtcctt ggatttactg aaaaaggtag gcaacatctc
    30901 aagtctttga aaggtcaggt cagtctagtc agccgaattg gcaaagaacc ttgggatgct
    30961 atgactcaaa aggttgacca gatttaccaa ctaggaaagc caagtatagc agagcaaaat
    31021 tttggcagag tgccaattag aatagaaaca aactaagtct actgaaaggt aggctttttg
    31081 agatttttta cgaataatac tcttcgaaaa tcaaattcaa atcgcgtcaa cgtcgccttg
    31141 ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta
    31201 taaatagata gaaaagaaaa tcttgtacaa gttcctgaca atttctttct tttcgtgtat
    31261 aatagtggaa aagagctaaa acgaggtatg gttatggaag cagtccttta ctcaacattc
    31321 cgaaatcatt taaaggacta catgaagaag gtaaatgatg aatttgagcc tttgacggtg
    31381 gtcaataaaa atccagatga ggacattgta gttctttcaa agagcgaatg ggacagtatt
    31441 caggaaaccc tgagaatcgc ccaaaataag gagttatcag acaaggtttt acgaggaatg
    31501 gctcaagtcc gtgctggaag cactcaggtc catgtgattg aggagtgatg aatgctactc
    31561 aagtttacag aagatgcctg ggcagattat tgctactggc aaaaccaaga taaaaaaaca
    31621 ctaaaaagaa tcaataaatt aatcaaggat attcaacgcg atccatttac aggaatagga
    31681 aaaccagagc cactcaaata tgattaccaa ggagcctggt cacggcgtat tgatgcagaa
    31741 aatcgcttga tttatatgat ggatggagat agcgtggctt tcttgtcctt taaagatcat
    31801 tactaagtct actgtaaagt aggctttttc tcaagtctct actaaactac tatttctaaa
    31861 caacaagttt atttttgcaa atgtgttcca aattccccaa aacatattct attttaggtt
    31921 tgtgaaaatc acttttttat ggtagaatgt aaaagaatgt atgtcattcg gaataacaat
    31981 aaaatgaggt aaaaacatgg aaatcatgtc gcttgcgatt gctgtttttg ccgtcatcat
    32041 tggtttagtc attggatatg tcagcatctc agctaagatg aaatcatctc aggaagctgc
    32101 agagttgatg cttttaaatg ctgaacaaga agcaactaat ttacgtggac aagctgagcg
    32161 tgaagcggat ttacttgtta atgaagccaa acgtgaaagc aagtctctta aaaaagaagc
    32221 actattggag gccaaagaag aagccagaaa ataccgtgaa gaagtggacg ctgaattcaa
    32281 atcagaacgt caagaactca aacaaatcga aagtcgtttg acagagagag ctactagcct
    32341 tgaccgtaag gacgacaatt tgacgagtaa agaacaaaca cttgaacaaa aagaacaaag
    32401 tatttctgat agagcgaaaa accttgatgc gcgtgaagag caattagagg aagtcgaaag
    32461 acaaaaagaa gcagaactag agcgtattgg tgctctgtct caggcagaag cacgagatat
    32521 tatcttggct cagacagagg aaaacttgac cagggagatt gccagtcgca ttcgcgaagc
    32581 tgagcaagag gtcaaggaac gttctgacaa aatggccaag gacatcttgg ttcaagctat
    32641 gcaacgtatc gctggtgaat atgtagcgga gtcaacaaac tcaacggttc atctgccaga
    32701 cgatactatg aagggacgca ttattggtcg tgaaggtcgt aacattcgta cctttgaaag
    32761 tttgacaggg gtcgatgtga ttatcgacga tacaccagaa gtggtgacct tgtcaggatt
    32821 tgatccgatt cgtcgtgaga ttgcccgtat gactatggaa atgttgctca aagatggtcg
    32881 tatacatcca gctcgtatcg aagagttggt tgagaaaaac cgtcaagaga ttgacaataa
    32941 gattcgtgaa tacggtgagg ctgctgccta tgaaattggt gcgccaaacc ttcatccaga
    33001 cttgatgaag attatgggac gtttgcagtt ccgtacttca tatggacaaa atgttttgcg
    33061 ccattcgatt gaggttgcta agttggctgg tatcatggcg agcgaacttg gtgaaaatgc
    33121 ggctcttgcc cgtcgtgctg gattccttca cgatatcggg aaagccattg accatgaggt
    33181 tgaaggtagc cacgttgaaa tcggtatgga attggcccgt aagtacaagg aacccccagt
    33241 tgtggtgaat acgattgcta gtcaccacgg agatgttgaa gctgagagcg tgatagcagt
    33301 tatcgtcgct gcagcagatg ccttgagcgc agcccgtcca ggtgctcgta gtgagtctct
    33361 tgaaagctac atcaagcgtc tccatgattt ggaagaaatt gctaacggct ttgaaggagt
    33421 gcaaactagc tttgcccttc aagcaggacg tgaaattcgt atcatggtca atccaggaaa
    33481 aatcaaggac gacaaagtca caatcttggc tcacaaagtt cgtaagaaaa ttgaaaacaa
    33541 tctcgattat ccaggaaata tcaaggtaac cgtgattcgc gagcttcgtg cagtagatta
    33601 tgctaaataa ataagaaaga gcagttgaaa aattactgct tttttgttac actagataga
    33661 aagactgtaa aggataatct ggctttttgc cattattcta gagaaatgtt atttcacaga
    33721 ttgactaaaa ggagacacaa tggcagaccg aggcttacta atcgtttttt ctggtccttc
    33781 aggggttgga aaaggaacgg ttagaagaga gatttttgag agttctgaaa accaatttca
    33841 atattctgta tcgatgacga cacgcgcaca acgtcctgga gaagtggacg gtgttgacta
    33901 tttcttccgt actcgtgaag aatttgaaga gctgattcgt caaggacaga tgttggaata
    33961 cgcagaatat gtcggcaact actatggaac tcctctgacc tatgtcaatg aaaccttgga
    34021 caagggaatc gatgttttcc ttgaaattga agttcagggt gctcttcagg tcaagaaaaa
    34081 ggttccagat gctgtcttta tcttcctgac accaccagat ttggatgaat tgcaagatcg
    34141 cttggtaggt cgtggaacag atagtgcaga agtgattgcc caacgaatcg aaaaggccaa
    34201 ggaagaaatt gccctcatgc gtgagtatga ttatgcgatt gtcaacgatc aggtgcccct
    34261 agctgctgaa cgtgtcaaat gtgtgattga agcagaacac ttctgtgtgg atcgtgtcat
    34321 tggtcactat caggagatgt taccaaaatc tccaactacc cgataaaatt tagaaaatag
    34381 gtacaagcaa atgatgttaa aaccctctat tgataccttg ctcgacaagg ttccttcaaa
    34441 atattcactc gtaatcttgg aagcaaaacg tgcccacgaa ttggaagcag gtgccccagc
    34501 aactcaaggt tttaagtctg aaaaatcaac tcttcgcgct ttagaagaaa tcgaatcagg
    34561 aaacgttaca attcacccag atccagaagg aaaacgtgaa gcagtgcgtc gccgtatcga
    34621 agaagaaaaa cgccgcaaag aagaagaaga aaagaaaatc aaagagcaaa ttgctaaaga
    34681 aaaagaagat ggtgaaaaaa tttaaggttg gggggactca atcttatttt ttctattgca
    34741 agaatgtact gacaaggagg aggtgagacg atggccctag ctaagattat cgtagatgtg
    34801 cccttgatgc agacggacca gccctatagt tacaggattc cggaggaatt tgagggaatg
    34861 ctggaagttg ggatgcgggt tcatgtgcct tttggtaagg ggaatcgcct gattcaaggg
    34921 attgttcttg gtttggagtc ccaatcagat ggagaagaga tggagcaaga tttaaaagat
    34981 attgcagagg tgctggattt ttctcctgtt ctcacgccag aacaactctg gctggctgag
    35041 gagttacgca aatctgtctt ctcctacaaa atttctatcc tcaaggctat gcttccagga
    35101 tttctgaatt ctagctatga caagattctc tatcctctgg aaggcttgag tcaggaagaa
    35161 cgagtgcgcc tgtttggttc agaagattcg ctagcctttt cttcactaga ccttgccaag
    35221 caagctgaaa tgatgcgttt gactagaaaa ggcctgcttg gtctggaata tcaggcagtc
    35281 gatcaaaaga aggtcaagac ccagtcttgg tatgaggttg accatgctca attagaaggt
    35341 gttgagattt ctacacgtgc caagaaaaag ttggaactga gagattatct gctgtctcat
    35401 ccagagagcg cttccttggc tagcttgtta gagtcctact cgcgagagca agtcaacttc
    35461 tttgtggatc aaggtgctgt taccatagtc caaaaggaag ttcaacgctc ggctgcttat
    35521 tttgaaggaa ttgaagcaag tagacctttg gagttaaatc cagaacaaag acaggcgcgt
    35581 gatgcggttg tgagttctat tggcagttct caacctccct ttctacttca agggattaca
    35641 ggaagtggga agaccgaggt ttacttgcag attatccaag gtgccctgga taagggcaag
    35701 acagcgattt tgctggtacc tgagatttcc ttgactcctc agatgaccga gcgttttata
    35761 gcacgttttg gggacaaggt agccattctt cactcaggat tatccaatgg tgaaaagtat
    35821 gatgaatggc gcaaggtgga gcgtggcgat gcccaagttg ttgttggtgc cagatctgct
    35881 atctttgctc ctctgaaaaa tctgggtgtc atgattattg atgaagagca tgaagcggct
    35941 tataagcagg acagcaatcc ccgttaccat gccagagagg tagctatttt acgggctcag
    36001 tataatcaag caactctggt acttggatct gcaacgccga gcttagagag ccgggcacgt
    36061 gctggcaaag gcgtctatca acacttacgt ctaacccaac gtgccaatcc tttggctaca
    36121 atccctgagg ttcaagtgat tgactttcga gactatatcg gacaaaatga gacgtcaaac
    36181 tttacgcctc ctttgctaga ggctatccaa gaccgtctgg ttaaaaaaga gcaggtggtt
    36241 ctcatgctca atcgccgtgg ttattctagc tttgtcatgt gtcgggagtg tgggacggtg
    36301 gatacttgtc ccaactgcga tatttctctg accttgcata tggataccaa gactatgaac
    36361 tgccattatt gtggtttctc gaaggatatt cctcaggtct gtcctaactg taagagccgc
    36421 agtattcgtt actatgggac gggaactcag aaggcttatg atgagctagc agaactcttt
    36481 ccccaagctc gcattttgag gatggatgtg gatacgactc gaaagaaagg cagtcaccaa
    36541 gccttgcttg accagtttgg gcgaggggaa gcggatattt tacttggtac tcagatgatt
    36601 gcaaagggtt tggattttcc caatgttacc ctagtcggag ttctaaatgc ggatacggcc
    36661 ttgaatctgc ctgatttccg ttcttctgag agaaccttcc agctcttgac tcaggtggca
    36721 ggtcgagcag gtcgggctga aaaagcaggt caagtcttga tacagtccta caattcgcag
    36781 cactatgcta ttcgatttgc caaggatcaa gattacgaag gcttttatgc ctatgaaatg
    36841 ggaatcagac gacaactcgg ctatccacct tactatttca cgattggtat taccctttct
    36901 cacaagaaag aagaagaggt tttcaaacgt gcctatgaag tcatgaacat tttgcggtca
    36961 ggcttgtcag agaccagtcc cattctgggg ccaacgccaa aaccgattgc ccgtacccac
    37021 aacctctatc attaccagat tttaattaaa taccgtttag aagatgagct ggggccgacc
    37081 ctcaaccagg tcttggcctt gactcaagaa cgggaaaata gtgagctccg tctcagcatt
    37141 gaccatgagc cgcagcaatt tttataagaa ggagaagata tgacaaaact aatctttatg
    37201 gggacccccg acttttcagc aacagtctta aaaggacttt tgacagatga ccgttacgaa
    37261 attctagccg ttgtgaccca gccagaccgt gctgttggtc gtaaaaaagt tatccaagaa
    37321 accccagtca agcaggctgc caaggaagca ggactatcta tctaccaacc tgaaaaatta
    37381 tctggaagtc cagagatgga agaacttatg aagctaggag cagatggaat tgtgactgct
    37441 gcttttgggc agtttctccc aagcaaactc cttgatagca tggactttgc tgtcaacgtt
    37501 catgcctccc tccttcctag acaccgtggt ggtgcgccta tccattatgc cttgattcaa
    37561 ggggatgagg aagctggtgt gaccatcatg gaaatggtta aggaaatgga tgcaggagat
    37621 atgatttctc gtcgcagcat tccgatcaca gatgaggaca atgttggcac cttgtttgaa
    37681 aaattggcgc tagttggtcg tgatttgctt ttggacactc tgcctgccta tattgctggt
    37741 gatatcaaac ctgaaccgca ggatacgagt caggttacct tctctccaaa tataaagcca
    37801 gaggaagaaa aactggactg gaacaaaacc aatcgtcaac tctttaacca aattcgtgga
    37861 atgaacccct ggcctgttgc ccatactttc cttaagggcg accgctttaa gatttatgaa
    37921 gccctaccag tagaaggtca gggaaatcca ggtgagattc tctctatcgg caagaaagaa
    37981 ttgattgtcg caacggctga aggggctcta tccctcaaac aagtgcagcc agctggtaag
    38041 cctaagatgg acattgcttc cttcctcaac ggagttggac gtacattgac tgtaggagaa
    38101 cgatttggtg actaaagtag aaacggctag aagtttagct ctagcagtgc tagaggatgt
    38161 ttttgtgaac caagcatact caaatatcgc cttaaataag catctaaagg ggagtcaact
    38221 tttggcagca gacaagggct tagtgaccga gctggtctat ggaacggtag cccgtaaact
    38281 gactctggaa tggtacctat cccactttat cgaagacaga gaccagttag acagctggct
    38341 ctatgtcctt cttctcatga gtgcctacca actccgctat ttggacaaga ttccagatca
    38401 tgctgtggtc aatgaagcag tggaattagc caaactccgt aaaaaaggca gtgaaaaatt
    38461 ggtcaatgcc ctccttcgcc gtatcttgcg tgaaggctgg ccagatattg ctagcatcaa
    38521 gcgaaaaaac aaacgtgact ccattgccta ttctctccca gtttggctag ttgccaaact
    38581 caaggaagaa tacggagagg agagagcaaa agccatcttt gaaagcctgt tagtgcgaaa
    38641 caaagccagt attcgtgtaa cagacctaag tcgaaaagag gaaatccaag ccttgttgga
    38701 ggcgaatgat tcccttttag caaccactgg tctggttaag gagcaggggc attttgcagg
    38761 gcataatttg tttgcggatg gagccattac catccaagac gagtccagtc agctggttgc
    38821 tccgacgctt gatttacaag gtgatgagcg agtgcttgat gcctgtgcgg ctccaggtgg
    38881 gaaaacagcc catatagcct cttatcttac gacaggtcag gttactgctc tggacttgta
    38941 cgaccacaag ttggatttaa ttcaagaaaa tgcccaacgt ctgggagttg aagatcgggt
    39001 tcaaactcaa aaattggatg ccagaaaggt gcatgagttt tttgaccagg attcctttga
    39061 taagattttg gtggatgctc cttgttcagg aatcggtctt ttgcgccgaa aaccagatat
    39121 caaatacaat aaagaaacgg cagatttcgc gtccttgcag gaaattcagt tagaaatatt
    39181 aggtagtgtt tgtcaaatac taggcaaagg tggtataata acttatagca cctgcactat
    39241 cgtctcagag gagaattttc aagtcgttaa ggccttttta gagagtcatc ccgagttcga
    39301 gcaggtaaaa ctagaacatg aatgtaagga tatcatgaaa gacggctgta tcctcattac
    39361 acctgaattg tatggaagtg atggattctt catcagtcaa tttcgcaaga tatcggatta
    39421 ggaaggaact gacacatgga aatttcatta ttaacagatg ttggtcagaa acgaacaaat
    39481 aaccaagact atgtcaacca ctatgtcaat agagctggac gtaccatgat tattttagct
    39541 gatgggatgg gaggtcatcg tgcagggaat atcgctagtg aaatggcggt cacagacctg
    39601 ggtgtagctt gggttgatac ccagatcgat acagtcaatg aagtgcgtga atggttcgcc
    39661 cattacctag aaattgaaaa tcaaaagatt caccagcttg gtcaggatga agcttacaga
    39721 ggcatgggaa ctactttgga agtccttgct attattgata atcaggctat ctatgctcat
    39781 attggtgatt cgcgtatcgg cttgattcgt ggagaagaat accatcagtt gacgagcgat
    39841 cattccttgg ttaatgaatt gctcaaggct ggtcaattga caccagaaga ggcagaagct
    39901 catccgcaaa aaaatattat cacccagtct attgggcaaa aagatgaaat tcagcctgat
    39961 tttgggacag ttatccttga gtcaggtgac tatctcttgc tcaatagtga cggcttgacc
    40021 aacatgattt caggcagtga gattcgtgat attgtaacca gtgatattcc tttagcagat
    40081 aaaacggaga cacttgttcg ttttgctaac aatgcaggag gtttagacaa cattacggtt
    40141 gcccttgttt ctatgaacga ggaggatgca gaatgatcca aatcggcaag atttttgccg
    40201 gacgctatcg gattgtcaaa cagattggtc gaggaggcat ggcggatgtc tacctagcca
    40261 aagacttaat cttagatggg gaagaagtgg cagtgaaggt tctgaggacc aactaccaga
    40321 cggacccgat agctgtagct cgttttcagc gtgaagcgag agctatggca gatctagacc
    40381 atcctcatat cgttcggata acagatattg gcgaggaaga cggtcaacag tatcttgcaa
    40441 tggagtatgt tgctggacta gacctcaaac gctatatcaa ggaacattat cctctttcta
    40501 atgaagaagc agtccgtatc atgggacaaa ttctcttggc tatgcgcttg gcccatactc
    40561 gaggaattgt tcacagggac ttgaaacctc aaaatatcct tttgacacca gatgggacgg
    40621 ccaaggtcac agactttggg attgctgtag cctttgcaga gacaagtctg acccagacta
    40681 actcgatgtt gggctcagtt cattacttgt caccagagca ggcgcgtggt tcgaaggcga
    40741 ctgtgcagag tgatatctat gccatgggga ttattttcta tgagatgttg acaggccata
    40801 tcccttatga cggggatagc gcggtgacca ttgccctcca gcatttccag aaacccctgc
    40861 cgtccgttat tgcagaaaat ccatctgtac ctcaggcttt agaaaatgtt attatcaagg
    40921 caactgctaa aaagttgacc aatcgctacc gctcggtttc agagatgtat gtggacttgt
    40981 ctagtagctt gtcctacaat cgtagaaatg aaagtaagtt aatctttgat gaaacgagca
    41041 aggcagatac caagaccttg ccgaaggttt ctcagagtac cttgacatct attcctaagg
    41101 ttcaagcgca gacagaacac aaatcaatca aaaacccaag ccaggctgtg acagaggaaa
    41161 cttaccaacc acaagcaccg aaaaaacata gatttaagat gcgttacctg attttgttgg
    41221 ccagccttgt attggtggca gcttctctta tttggatact atccagaact cctgcaacca
    41281 ttgccattcc agatgtggca ggtcagacag ttgcagaggc caaggcaacg ctcaaaaaag
    41341 ccaattttga gattggtgag gagaagacag aggctagtga aaaggtggaa gaagggcgga
    41401 ttatccgtac agatcctggc gctggaactg gtcgaaaaga aggaacgaaa atcaatctgg
    41461 ttgtctcatc aggcaaacaa tccttccaaa ttagtaatta tgtcggccgg aaatcttctg
    41521 atgttatcgc ggaattaaaa gagaaaaaag ttccagataa tttgattaaa attgaggaag
    41581 aagagtcgaa tgagagtgag gctggaacgg tcctgaagca aagtctacca gaaggtacga
    41641 cctatgactt gagcaaggca actcaaattg ttttgacagt agctaaaaaa gctacgacga
    41701 ttcaattagg gaactatatt ggacggaact ctacagaagt aatctcagaa ctcaagcaga
    41761 agaaggttcc tgagaatttg attaagatag aggaagaaga gtccagcgaa agcgaaccag
    41821 gaacgattat gaaacaaagt ccaggtgccg gaacgactta tgatgtgagt aaacctactc
    41881 aaattgtctt gacagtagct aaaaaagtta caagtgttgc catgccgagt tacattggtt
    41941 ccagcttgga gtttactaag aacaatttga ttcaaattgt tgggattaag gaagctaata
    42001 tagaagttgt agaagtgacg acagcgcctg caggtagtgt agaaggcatg gttgttgaac
    42061 aaagtcctag agcaggtgaa aaggtagacc taaataagac tagagtcaag atttcaatct
    42121 acaaacctaa aacaacttca gctactcctt aaaagcagat ggataatcaa aatgagtaat
    42181 caatctttgt catgatttca tggcaaagat tttttttgag tccagatttg tgatagaata
    42241 gagggagttg ataaaaggag gaaagcatgg aagaatcaaa agaattaaat gccgtcattg
    42301 atgtgattat gctagcgggg actattctcc ttaaaagtgg ctcagaaatc catcgtgtag
    42361 aagataccat gattcgaatc gcgcattcgc aggggattgt ggattgcaat gtccttgcca
    42421 tgcctgccgc tatctttttc tctattgaaa ataccaatat ttcgcgcatg aagcgcgtga
    42481 cctcctcttc ttataacatc gaaaaagtct gcgatgtgaa ccagatttct cgtcagctag
    42541 ttggggggca gattgactta gaaacagcct ttaagcaatt gacggccttg caagctcaac
    42601 cccttcccta tactaagttg caggtaactc tggctgcgac ctttagtgct cctttctttt
    42661 cagttatgtt tagcggaaat atctacgacg cacttggggc aggagtggcg accttatttg
    42721 gttttgcctt ttccctctat gtggaaaaat ttatccgaat tccctttgtg acagcctttg
    42781 ctggagcctt tgtctttggg ataattgccc agttttgggc tcgctacaca ggttttcctt
    42841 caacggcaga tttgattata gctggtgcgg tcatgccgtt tgtaccaggt attgccttga
    42901 ccaatgcggt ccgtgatatt atgaccaacc acataaactc tggtatgagt aagatgtttg
    42961 aatccctgct cattaccctc gctttagggg caggaacttc tgtcgccttg gtattgatga
    43021 actaatatga cactaacaac ctttttatta caagcagtag caagttttct tgccattatc
    43081 acttttttaa tcgtactcaa tgtgcaacgg tctatgctct tacctggagg gattttgggc
    43141 atgactgtct ggctaatcta tctcttgctc aaggaaccga ccaatgtcat tgtagctacc
    43201 ttcattgcag ccattattgg ttcttgtgtc agccagattt taagtattct ttataagaca
    43261 cctgctgtgg tctttatctt ggccattttg gcaccgctgg ttccaggtta tctctcctac
    43321 cgaacaactg ccttttttgt gacaggggac tataataaag cactggcaag tgcgaccttg
    43381 gttgtcatgt tggctctggt aatctctatt ggaatggcta gcggaacagt gattctcaga
    43441 ctgtatcatt atataaaaac acatcgagta tcgtagactt tacagaaata aaagaatttt
    43501 ctgaaaaatg agataaataa attaacaacg ctttctatat gtgcgagaat accgcactta
    43561 tgaagaaatt acggctgatt ttggtatcca cgaaagcaac ttaatccgtc ggagccaatg
    43621 ggttgaagta actcttgttc aaagtggtgt tacgatttca aaaactcatc ttagtgctga
    43681 gaatacggtg attgtggatg caacagaggt aaaaataaat cgtcctaaaa aaatcaacta
    43741 gccaattatt ctggtaaaat agaaatgtca ttctatggaa cctcaagcga ttgtcacaag
    43801 tcaagggaga attgtttctt tggatatcgc tgtgaactat tgtcatgata tgaagttgtt
    43861 caaaatgagt cgcagaaata tcggacaagc tggtaaaatc ttggttgaca gtggttatca
    43921 agggctcatg aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc
    43981 gctaacagct gaagataaag cctgtaacca tgcgctatct aaggagagaa gcaaggttga
    44041 gaacatcttt gccaaagtaa aaacgtttaa aatgatttca acaacctatc gaaatcatcg
    44101 taaacgcttc ggattacgaa tgaatttgat tgttggtatt atcaatcatg aactaggatt
    44161 ctagttttgc aggaagtcta ctattttcct tattgtctgt aagtctactg accttgttgt
    44221 ttatcccagt catggtttct agttcgggct cagagtttca aagtggatgg caagagcatc
    44281 aattgattgc tgagaaggtt agtaaaacac ttgacaagac atttgataag gatgtcagag
    44341 aaattccgac cagtcagttt tatcaaaaat ttgtagatga gatgggaagg acttactcag
    44401 gaaatttgat cctccaggag ctgataactg tgaatggagc ttataaagct acttatatcg
    44461 atgaactctc tagcaactaa tcattcttta aaatgatgac caataagagg cttgatttgg
    44521 tgaatcaagt cttttttctc tcttttactg ccatttgtga taaaatagta tagaacgatt
    44581 ttttacatga atgataaaac agaggtaaat atgacaatcg gtattgataa gattggtttt
    44641 gcgaccagtc aatatgtctt gaaattacaa gacttagcag aagcgagggg aattgaccct
    44701 gaaaaattaa gtaaaggact cttactcaag gaattgagta ttgcgcccct aactgaggac
    44761 atcgtgacct tggcggccag tgctagtgac tctattttaa ctgagcaaga aagacaagaa
    44821 gttgacatgg tcattgtagc taccgagtca ggaattgacc agagtaaggc tgcggccgtc
    44881 tttgtgcatg gcttgctggg catccagccc tttgctcgta gtttcgagat taaagaagcc
    44941 tgctatgggg cgacagctgc cctccattat gccaaattgc atgtggaaaa ttctccggag
    45001 tccaaggtct tggtcattgc cagtgatatt gccaaatatg gtattgaaac tccgggagaa
    45061 cccactcagg gtgccggaag tgtggctatg ttgattacac aaaatccacg catgatggcc
    45121 tttaataatg acaatgtagc tcagacccgt gacatcatgg atttctggcg accaaattac
    45181 tcgacaactc cttatgtaaa tggtgtctat tctacccaac aatacttgga tagtttgaaa
    45241 acgacttggc ttgaatatca aaaacgctac cagcttactt tggatgattt tgcggctgtt
    45301 tgtttccact tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat catggataag
    45361 agcctgcctc aagagaaaaa agacctctta caaaagcatt ttgaccagtc tattctctac
    45421 agtcaaaagg tggggaatat ctacacaggt tcacttttcc ttggactttt gtctctcttg
    45481 gaaaatacag atagcttgaa agctggggat aaaatcgtcc tttatagtta cggaagtgga
    45541 gctgtggctg agttcttcag tggtgaattg gttgaaggat atgaagctta tttggataaa
    45601 gaccgcttga acaagctcaa ccaacgaact gccctatccg ttgcagacta tgaaaaggtc
    45661 ttttttgagg aagtaaactt ggatgaaaca aactctgccc agtttgctgg ctatgaaaat
    45721 caagattttg ccttggttga aattctcgac caccaacgcc gttatagcaa ggttgaaaaa
    45781 taatgaagat aagttggaat ggattttcta aaaaatcata ccaagagcgc ctcgagctgc
    45841 taaaagctca ggcgctcctt agtcctgaga gacaagctag tctggagaag gatgaacaga
    45901 tgagtgtgac tgtggcagac cagctgagtg agaatgtggt gggaactttt tctctgcctt
    45961 attcgctggt tccggaggta cttgtcaacg gtcaggaata caccgttccc tatgtgacag
    46021 aagaaccctc tgtggttgcg gcggccagct atgccagcaa aatcatcaag cgtgcaggtg
    46081 gttttactgc acaagtccat cagcgccaga tgattgggca ggtagccctt tatcaagttg
    46141 ctaatcctaa actagcgcaa gagaagattg ccagcaagaa agcggagctc ttggagcttg
    46201 ccaatcaagc ctatccttct atcgttaaac gtgggggtgg ggcgcgtgat ctgcatgtcg
    46261 agcagataaa aggcgaacca gactttctcg ttgtttatat tcatgtcgat acccaggaag
    46321 ccatgggtgc caatatgctc aacaccatgc tggaagcctt gaaaccagtc ttagaagaac
    46381 tcagtcaggg acagagtctc atgggaatcc tgtccaacta cgcgaccgat tctctggtga
    46441 ctgcaagctg tcgcatcgcc tttcgctact tgagccgcca aaaggatcaa ggacgagaga
    46501 ttgcggagaa aattgcgttg gctagtcagt ttgcgcaggc tgatccttac cgagctgcta
    46561 ctcataataa aggaattttt aatggtattg atgcgatttt gattgccact ggtaatgact
    46621 ggcgtgccat cgaagctggg gcccatgcct ttgccagtcg agatggacgt tatcaaggtc
    46681 ttagttgctg gacgctggac cttgaaagag aagaattggt cggtgagatg accctgccca
    46741 tgcctgtagc gactaagggt ggctctatcg gcctcaaccc acgtgtagct ctcagtcatg
    46801 atctactagg aaatccttct gccagagaat tagcccagat tatcgtgtcc atcggtcttg
    46861 cccaaaattt tgcagccctc aaagctttgg taagtacggg catccagcaa ggccacatga
    46921 aactacaggc caaatcccta gctctcctag ctggggctag tgaatctgaa gttgctcccc
    46981 tagtagagcg cctcatctca gataaaacct ttaacctaga gacagcccag cgctatctcg
    47041 aaaatttaag atcataaaaa actcagacga atcggtctga gttttcttgt gtttaaatac
    47101 tttttcctgg taatagcgta actggtaaga agtaaccagt tgtggcgact tccttgcctt
    47161 caatcttttg caagagaaga tcaatagtga gacaagcaat ctcttccaaa ggttgcttga
    47221 tagtagccaa ttgagggtag taattttcga taaagtaggt cccatcatag ccgatgacct
    47281 tgagctcttt tgggacagaa atgcccaatt cttgagcgat tttaatgacc agaatagctg
    47341 tcaaatcatc cgaagcaaaa atggcatctg gtttttcccg ggtcaagata ttcttgattt
    47401 ccatttcttt tctgacggga gaaaagtcac tggaaacatt gataatagga gcttttggga
    47461 gtacggatgc aaaaccagcg tggcgcagtc cggttggcga attggaattg tcattccctg
    47521 taatcatgat gatagactgg gcacctgtct tgaccaaggt ttgggcagca agaaccccac
    47581 cagcatagtt gtcagaggag acgacaggga tgtctggcga taggtttcgg tcaaaggaaa
    47641 taatcggcgc tgtcacacga ttgtagtctt cgattcctag gttgtgacta ccagaaatga
    47701 tgccgtccac ctgattggct tccaacattt cgatgtattc gcgttccttc tcagaatcat
    47761 gttcactgtt gcagatgatg gtcttgtaac catttttgaa gagttggtgt tccaatttat
    47821 caatcaattc tgcatagaaa acattggaaa tattggggaa aatcaagccg attaacttag
    47881 ctgattttcc ttgcagacta cgagccaggt tgttgggttt atagcccaat tctctcatgg
    47941 cttcattgac tttttggatg gttttctcag atagataccc ttttttattg ataacccgag
    48001 aaacggtagt aggactgacg cctgcaagtt tggcgacatc agttagtttt gcgaccataa
    48061 tctaattcat agtaagttcc agttgggttt ccagatttga tcaggatacc attttggtcc
    48121 gcatgtggga agacacgacc agaaaatact ttttctcctt tattgatgaa aatttcaaag
    48181 acagagttat cgatgaagat tgtagcagta gtagcctgat tctcgatagg gcaagaacga
    48241 gttgtcccaa attcttgggc atactgttct ccagcctggc tacgatccac tgtcacttga
    48301 ccgtttacaa ggtcaaagtt gattgaaagt cccttacctt ctttatcagc aagtaagaca
    48361 atctcgctct ggctattagc ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg
    48421 gaacggtttg agaaggcttc ttcagaagca cgaaggtcct taatagcagc gactggatac
    48481 tggtagagct tgtcgtcttt gatagtgagt tccttgacca aagagaaggt tccttggtgg
    48541 tcaaaacggt cagatgggta agaaacatct ggcaaaccaa gccagctaac tgctagagca
    48601 cgcccatcag gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta atccatgttt
    48661 tgaagttgag acacatctac cattttggca tttttagggt caaaggaagc cccaatctta
    48721 tacatatttg gaaagatatt atcgtagtct agaactttct tatccaatcc ttgtggacag
    48781 tagagaagga caggctgttc ctctacaaag accagattag gacattccat catgtaggca
    48841 gtacggtcgt tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta gtcgttattg
    48901 acagccttgt agagacggac gaagcctttt ttctccaagt cttgtccgcc gacaatggca
    48961 taatattgac cctgaaagtt aaaaatttgt ggatcgcgga agtggtcagt agagtctgct
    49021 ggctggtcaa tcaagatctt gtcaatcttt gtaatcttac cctccttgtc catcaaagca
    49081 ccgatctggt atgggtgacg gatccagttt ttatcgcgaa catttcctgt ataaaatagg
    49141 aataagttat cgccaaattg catggcagaa ccagagtagg caccgtggct atctaatgga
    49201 gtatctggta aaactttgac tccagtttct ctaaagtgaa tcaaatcatc actttctagc
    49261 tgtgcccaag attttaaacc gtgggctgca ccaaaaggaa aattctggta aaagaggatc
    49321 cacttgccat caaagtaaga aaagccattt gggtcgttga gaagtcctgt ttttggctca
    49381 acatggtaat gagtatgcca tggagattgt gccatatttt cctttatatg ttgaatttct
    49441 tcttgcgtcc aatcttgata aagtctgtaa cgacgctcag ttgtccattc cattcattcc
    49501 tccaaaaatc ttatcacttt taatagtaac tgttttcgat aaaaaatgca agccttttat
    49561 attaaaaaag agaaaaaact gtcaaacgat tatcataaaa taaatacagg aaatcaatca
    49621 aatttttacg aaaatgtgaa agataatgaa ataaaagact ttttaaccaa ggtttcaaat
    49681 ttatttttca aggaattcct gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccac
    49741 taagtggata gaatattttt ctgcaaaacg cttgacatat ttttaaaaca tgataaaata
    49801 atagtcgtaa gggcgaataa aatcgctttc aaacaagaac aaaatgttat ataaggagat
    49861 ttttgcaaat gaacaatcag gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg
    49921 aaaatgtcaa tagtgttgct cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag
    49981 agaaaatcaa taaagaagtg attgagaact tggaaaaagt tcaaggtgct ttctttaact
    50041 cagggcaata ccaaattatc tttggtacag gtacagttaa caaaatgtac gatgaagttg
    50101 ttgtacttgg cttaccaaca tcatctaagg atgacatgaa agcagaagtt gctaaacaag
    50161 ggaactggtt ccaacgtgct atccgtactt tcggtgatgt tttcgttcca atcatcccag
    50221 ttatcgtagc gacaggtctc ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc
    50281 cacttccagg tgactttgca acttacacac aaatcttgac agatacagcc ttcatcatct
    50341 tgccaggttt ggttgtgtgg tcaaccttcc gtgtatttgg tggaaatcct gccgttggta
    50401 tcgttcttgg tatgatgctt gtctctggct cacttccaaa cgcttgggca gttgctcaag
    50461 gtggtgaagt aacagcgatg aacttctttg gtttcatccc tgttgttggt ttgcaaggtt
    50521 ccgttcttcc agccttcatc atcggggttg tcggagctaa atttgaaaaa gctgtccgca
    50581 aggttgttcc agatgtcatt gacctcttgg taacaccatt cgtgacactt ttggtcatgt
    50641 ctatccttgg actctttgtc attggaccag ttttccacgt tgttgaaaac tacatcctta
    50701 ttgctacaaa agcgattctt agcattccat ttggtcttgg tggtttcttg attggtgggg
    50761 ttcaccaatt gatcgtcgtg tcaggtgtgc accacatctt caacttgctt gaagtgcaat
    50821 tacttgctgc tgaccatgct aacccattca acgctatcat cacagctgct atgacagctc
    50881 aaggtgctgc tactgttgcg gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg
    50941 ctttcccggc tgctctttct gccttcctag gtattacaga gcctgctatc ttcggggtga
    51001 acttgcgctt ccgtaaacca ttcttccttt cattgattgc tggtgcaatc ggtggtggat
    51061 tggcttctat ccttggactt gctggtactg gtaatggtat caccatcatc cctggtacaa
    51121 tgctttatgt tggtaacgga caacttccac aataccttct tatggtagct gtatcatttg
    51181 cccttggttt tgctcttact tacatgtttg gttacgaaga tgaagtagac gcaactgcag
    51241 ctgcaaaaca agctgaagtg gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa
    51301 atgaaacact tgtaactcct atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc
    51361 cagtcttctc aagtggagct atgggacaag gtatcgctgt gaaaccaagc caaggcgtgg
    51421 tctatgcacc agctgatgct gaagtttcaa ttgcctttcc aacagggcac gcttttggtt
    51481 tgaaaacaag aaatggtgct gaagttttga ttcacgttgg tattgacact gtatctatga
    51541 acggtgacgg ttttgaagca aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc
    51601 ttggaacatt tgactcaaac aaaatcgctg cagctggact tgatgataca acaatggtta
    51661 tcgttacaaa tacagctgac tacgcttcag tagctccagt cgcaacaggt tcagttgcga
    51721 agggggatgc tgtgatcgaa gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca
    51781 aatgacatgt ttgttcgttt ttattagata gtaagattta cagaggaaaa tctaaaaaat
    51841 agagacattt agactttcga agtatgctat aataaagaaa ataaaaacaa gaggtttatc
    51901 atgacaaaat tatatggaag cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt
    51961 gatgaaaact ttaacgtcgt agaaaaaaca caatttccaa caacaactcc aatcgaaaca
    52021 atcgataaaa ccattgagtt cttctcaaaa ttcgataacc ttgctggtct tgcagttggt
    52081 tcatttgggc cgattgatat tgacaaaaac tcaaaaactt atggctttat cacgacgact
    52141 ccaaaaccaa actgggcaaa tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg
    52201 ccaatgtact tcacaacaga cgtaaacagc tctgcttacg gtgaagtggt tgcccgtaac
    52261 aatgctggtg gtcgtatcga aaacttggtt tactacacaa tcggtacagg tatcggtgca
    52321 ggtgtcctcc aacgtggtga gtttatcggt ggtgtgggtc accctgaaat gggtcattat
    52381 tatgttgcta gacacccaat ggatattgaa aaagagttta agggtgtttg tcctttccat
    52441 aagggatgtc tagaaggtta tgcagctggt ccaagtttgg aagctcgtac aggtgtacgt
    52501 ggggaaacta ttgaattcaa caaccctgtt tgggatgttc aagcctacta tatcgctcaa
    52561 gctgcggtta atgcgacagt gactttccgc ccagacgtga ttgtctttgg tggaggggtc
    52621 atggctcaac aacatatgct ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt
    52681 tacctaccag taccagatgt gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt
    52741 tctgccacac ttgggaactt tgttcttgca aaagaagttt caaaataaag cacaaaatcc
    52801 gcttgggaaa ccaaacggat tttgtggttg aaaacaatat ttttgagcct ttccttaagt
    52861 gattacggac ggtagcgact ttcttcgaaa ttccatacct aaactttgag acactaggct
    52921 caaagtttcc gaatacctga aaccattaga tttcaggtgt ttctatcacg gcgggaaggc
    52981 taggtaagtc ctcgcctcac tatcgaaaaa tatgcatgat ttccatacca aagtatattt
    53041 agtatcaagc tatagttaat ctacgcttta aaaatccact tgggaaacca aacggatttt
    53101 ttacgtgtca aagcatttgc cagaaaaagt caataatata ggtcagaccg taggtataaa
    53161 ccacgagggt aaagggtttg gtcagaatga tgatagtcat gtagcgcttg aaactcatct
    53221 tggtcagggc agccagcata cagagaaagt cagctgggct aatgggccaa atcatcataa
    53281 aaataaagaa gcggtcaaaa cgattgccct tatctagcca gccgatgtac ttgtcgtagg
    53341 tgcgcttgct gacgacagac tggacaaagg cagctccgta taggcgcacc agataaaaga
    53401 taatggcaca gccaatcacg atgccgatat agttgtagat agtcccgatg atgtgcccgt
    53461 agataaagac cccagccacc gaggtcaagg cccctggaat gatagggacg acagtctgta
    53521 aaatctgtaa aaagataaag agaggtggac cccagatgcc tgcctgctgg ataaaggcag
    53581 agagggtttc cttggattgt aaaatcccag cctgataagc ccaaatacag aaaatcaaac
    53641 tcccaacccc accgacaatc gatgagatat tgataactcg ctgcagaagg ggagaaacag
    53701 ctttcatttg tttatcctgt gacatgtaaa ctcctcatag atagtatatt tctactatac
    53761 catattttgg aggagaaagg gggaatgagt cttttttgat aaggaataga aagtaaatag
    53821 cccttcgaga cttagaatag gtctgtcaac taaaggttat atgcattcta ggtttcgaat
    53881 aatcgcaatt ccataaattt aaaagcattc taagtttcga atagcttatc tgagataatt
    53941 ttgaggcatt cgcgctttcg aatagtcatt ttccctaaag tttagatgta ttctgaagct
    54001 agaaagacta aaatctaaaa gtagtaagag tctctctctg atggacgtaa tttatggcta
    54061 gtatgaatcc tttgaattgt tagttaattt taatattaat cagttctgaa ataattacta
    54121 aatatagtta gatggtgaat taattattgc taaatttcaa gttcaagtta gtcatccaga
    54181 agtcttctct gggggacttg tagttcaagc attttttagg atagttgtta atccactttt
    54241 cgatgaatgc gacttccttt gtagtcgttt tcttagttcc ctgaggtaac catctatgaa
    54301 tgaacttgtt gtgattttta ttagatccta tagtggtgtg cataatagat ataatagatt
    54361 gaaactagaa tagtacgcat ctacttctaa aacattgtta gaaatcgatt tgactgtccc
    54421 gatctatttg tcctgttttt atttcatttt actatataat ccttagaaaa tatatgggac
    54481 aagcggttga attccgttcc gtccattagt agataaagga ttactccttc ttgaaatgac
    54541 agatgaactt gtttcttata aaaatgttgt ctgaaactat tcgctttttt ccagaagttt
    54601 tagaggaaga aaactttatg aggaaaaagg agttactcaa ataacaattc aggattaaaa
    54661 atagacagtt gaggagcgga aggtataaat tgagtttgct actgtataat ggatttatca
    54721 ctaatactct tcgaaaatct cttcaaacca cgttagcttc gccttgccgt agatatagtt
    54781 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
    54841 tttatctgca acctcaaagc tgtactttga gcagcctacg gctagcttcc tagttcgctc
    54901 tttgcttttc attgagtata aaagtgctcc aggccatatt ttacacagca atagtcttct
    54961 aaaaatggac aaaaacattg taaaggctat caaaaaggag tataatgagt gcaagaaatt
    55021 tcggaggtga aagatgctag aagtaagaag tctagagaaa agttttggct ccaagcaagt
    55081 tttgtttggt attgactttc aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa
    55141 tggtgctgga aaaacaacga ttttccatag tattttgaaa ttcctagaat atcagggaga
    55201 aatcggtctg gatggtcagg atattcgtca ggagacctat gctcggattg gttatctgcc
    55261 tgaagaacgc agtctcatgc ctaaattgac agttcttgaa caagttcgct acttggcgac
    55321 tctaaaaggc atggatgcca aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt
    55381 gaaagtgaaa ggaaagctga cagataaaat caagagtctg tcaaaaggaa atcagcagaa
    55441 gattcagctc attattactc tgattcatga accagacctg attatcttgg atgagccttt
    55501 tagtggattg gacccagtta atacagaatt gctcaaacaa gtcatttttc aggaaaaaga
    55561 gcgcggagca accattatct tttctgacca tgtcatgacc aatgttgagg aactttgtga
    55621 cgatattctg atgatccgag atggccgtgt ggtcttgcac ggaccagttc aggatgtccg
    55681 caatcaatac gggaaaacgc gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga
    55741 aaatcttcct catgtcaaac aggtgagctt gaccaaacaa ggcagttgga aattgatttt
    55801 ggaggatgag agcgctggaa gggaactctt cccaatcttg actcaaggtc aatatatcgc
    55861 aacatttgac caacaagcgc caactatcga tgaaatcttt aaactagaat caggagtgga
    55921 agtatgagaa atatgtgggt tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg
    55981 agtttcttct ttatggtgat ttcgccgttc ctctttttag gaatctctgt aggaattggg
    56041 catatccaag gttcttctat ggctaaaaat aataaagtgg cagtagtgac aacagtgcca
    56101 tctgtagcag aaggactgaa gaatgtaaat ggtgttaact tcgactataa agacgaagca
    56161 agtgccaaag aagcaattaa agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa
    56221 gatagtgttc taaaggcagt ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt
    56281 gaggttacag gtacactcaa tgaactgcaa aatcagctta atcgttcaac tgcttccttg
    56341 tctcaagagc aggaaaaacg cttagcgcag acaattcaat tcacagaaaa gattgatgaa
    56401 gccaaggaaa ataaaaagtt tattcaaaca attgcagcag gtgccttagg attctttctt
    56461 tatatgattc tgattaccta tgcgggtgta acagctcagg aagttgccag tgaaaaaggc
    56521 accaaaatta tggaagtcgt tttttctagc ataagggcaa gtcactattt ctatgcgcgg
    56581 atgatggctc tgtttctagt gattttaacg catattggga tctatgttgt aggtggtctg
    56641 gctgccgttt tgctctttaa agatttgcca ttcttggctc agtctggtat tttggatcac
    56701 ttgggagatg ctatctcact gaataccttg ctctttattt tgatcagtct tttcatgtac
    56761 gtagtcttgg tagtcttggc agccttccta ggatctatgg tttctcgtcc tgaggactca
    56821 gggaaagcct tgtcgccttt gatgattttg attatgggtg gtttttttgg agtgacagct
    56881 ctaggtgcag ctggtgacaa tctcctcttg aagattggtt cttatattcc ctttatttcg
    56941 accttcttta tgccgtttcg aacgattaat gactatgcgg ggggagcaga agcatggatt
    57001 tcacttgcta ttacagtgat ttttgcggtg gtagcaacag gatttatcgg acgcatgtat
    57061 gctagtctcg ttcttcaaac ggatgattta gggatttgga aaacctttaa acgtgcctta
    57121 tcttataaat agaagagcct tgcgaaagcg aggtttttaa aggtgaaaag ggtggaatca
    57181 cgaacctaat tatgtacaca ttatgtaaac aagttgcttg aaaactcaat tgtatagtga
    57241 actgaatctg gaataggata atattacttc taaaacattc ttacaaattg atttgaattc
    57301 caaaatccca tcgttccgtt cttatttcat tttgcgatat agtgaaagga aataagtcag
    57361 ctcacaaaaa acgcataata tcaaggattt tttgaactgc cccccaaaag ttagattttt
    57421 tctgtctaac ttttgggggg cagttcatat tcaacacttg atactatgcg ttttctaatt
    57481 ttaaagactt tttgcctggt ctcttttgtt ctatgagtat gttacatatc taggtaaaaa
    57541 ttatttaaag caaattaacc ttatttctca agatgtagta ggttccgaga taaaagatag
    57601 ctatgaatat gagttcttca acaatggcta tacctgctcc catatagaaa tggtcattga
    57661 gtcctaccag tgaattgaca tagaaattag aactaagatt gaagaaaagt tcaataaatc
    57721 caatgacgat ttggatacca atgtagactg caacagcgag tgctgtacgg tattcattga
    57781 aaagctgtcc aatggaaata gccaggtaga tgcagaggat tcctgaaatg gtatttagta
    57841 ggaaggatat acctgtaaga aagatctgag ggagatgtgt ttctacaaat gtaatcacat
    57901 aagaaagagg aatccattct ggagctgtta aagccagaat aataacagca cttagagcca
    57961 atacagcggt gctaatcaat gaccagataa aggcaccgat tagtttggct gtgatgatat
    58021 ggtgttcaga aactggcaag gtcaaagtca gatagccttg tcggtcgtag acactacctt
    58081 tgaagcgttt aataatcaag aaaatggttg aaatcgcaag tgtaagcatc aagccaccaa
    58141 agactgtagc tagaaaaagt agcatagtag cctgactttc ttggtaaggt agatttttaa
    58201 agccttgtgt ctgtattccg atgagggcag aaaggactag cacggctgcg tagagggcta
    58261 aataccactt gttaacattt ttaaattcgt agtgaactaa attccaaaac ataaataatc
    58321 tcctttgctt aggccttaaa ttcctgacgg aagagttggt caatggattc acctgactcg
    58381 tagcgaatat catctacatt tccttgacgg acgacttttc cgtcttttag gaagacaatt
    58441 tcatccaaga ttggctcgat atcagaaatc aagtgggtag aaatcaaaac ggtagaagtt
    58501 ggtgagtagt tgttgataat ggtattgagg atataagcac gggctgctgg atccacccca
    58561 ccaatgggtt catccaaaac atagagacga gcatcacggc tcataaccaa aatcagttga
    58621 accttttctt tgtttccttt tgatagtttc ttgagacgac tattttcatc aatgcccagg
    58681 tctgcaagta gatgatgggc gcgttcaaga ttgaaatctt tatagaaggt cttgaagtag
    58741 gttagggctt ctttgacctt catttgctca ttgagatagg tcgtatcagg caaataagct
    58801 acaacggcct tggttgctgg gcttgggtcc atgtcgttga tgaggacacg tccttgatct
    58861 ggttgtaaga ggccattaat tagtttaatc agggttgttt ttcctgagcc gtttggccca
    58921 agaaggccga caatttttcc agctggaatg tcaagagaaa cattttcaag ggctggtgtt
    58981 gctccatatg atttggatac attttcaaat gctagtaatg acataggctt aaactccttt
    59041 aatataatca ctgactacgc ctggtagttc ttctttttca tagccaaaat gggtcatgga
    59101 ggaaacgaag tgttccaatt cttcttctga taattgtttg cgtgactggg cgattagctc
    59161 cttatcctta gtcacaaatc gtccagttgt tcgcttgctg tagacaaatc cttctcgttc
    59221 aaggtctgat aaggctcttt ggatggtatt gggattgaca ccagcctcgc tagctagctc
    59281 cctcacggtt ggaagttgtt gattgggttc cagtgtatgg gaaacaatct gaagcttgat
    59341 tttttccata atctgtaaat agatgggttt tttgttgtca aatgtccagg acatcttggt
    59401 ctcctttctc ttaccctttt gtcttaatta aataatacaa caaaacaaaa aacttgtcaa
    59461 gcaaaaagaa gaattgtttt gggaatcgct taaaaaatgg tataatgaaa agaaaacgat
    59521 aaggagggaa aggatgcgtt gtccaaaatg tggggctacc aagtcaagtg ttatcgatag
    59581 tcgccaagca gaagaaggga acaccattcg tagaagacgt gagtgcgacg aatgccaaca
    59641 ccgttttaca acctacgaac gagtagaaga aagaacctta gtggttgtta aaaaagatgg
    59701 cacacgggaa caattctcca gagataaaat ctttaatggg attatccgct cagcccagaa
    59761 acgtcctgtg tcaagtgatg aaatcaacat ggtagtcaat cgtatcgaac agaaactccg
    59821 tggtcgaaat gaaaatgaaa ttcaaagtga ggacattggt tcactcgtca tggaggagtt
    59881 ggctgaattg gacgagatta cctatgtacg ttttgctagt gtctatcgta gttttaaaga
    59941 tgtcagtgag ttagagagct tgctccaaca aatcacccag tcctctaaaa agaaaaagga
    60001 aagataaatg aagccaattg accgtttttc ttatctaaag aataatcggg tgtcgcaaga
    60061 tacctcatct ctggtacagt gctacctccc gattatcggt caggaggcac tgagccttta
    60121 tctttatacg attagttttt gggataatgg tagaaaggaa tatctttttt caagtatcct
    60181 caatcatctt aactttggaa tggatagact gataaaatca ttgaaaatct tatctgcttt
    60241 taatctcttg actctctatc aaaaggggga tgtttatcag ctagccctcc atgctcctct
    60301 atctagtcaa gacttcttgg ggcatcctgt ttatcgcaga ctcttagaga aaaagattgg
    60361 ggactctgct gtggaggatt tgaaagttga aagtgctgat ggtgaagaaa tacctgtctc
    60421 actcaatcaa gtctttccag aattggcaga actaggcagt caagaagacc ttggtctcaa
    60481 gaagaaagtg gccaatgatt ttgacttgga acattttcgc cagctgatgg ctcgagatgg
    60541 acttcgtttt gcggatgagc agtccgatgt cttaaacctc tttgctattg ccgaggagaa
    60601 gaaatggact tggtttgaaa cctatcaatt ggccaagtca acagctgttt ctcaggttat
    60661 ttcaaccaaa cgcatgcgtg aaaaaattgc tcaaaaacca gtttcctctg actttagtct
    60721 taaggaaaca accattatca aagaagccaa aagtaaaact gccctgcagt tcttggcaga
    60781 aatcaagcaa acacgcaagg gaaccattac ccaaacagaa agagaactct tgcaacagat
    60841 ggctggcttg ggcttgctgg acgaagtcat caatatcatt cttttattga cctttaataa
    60901 ggtcgattcg gcaaatatca atgagaaata tgccatgaag gtagccaatg actatgccta
    60961 tcaaaagatt cattcggcag aaaaggcagt cttgcgcatc cgtgagcgag aacagaaagc
    61021 aaaaacacaa aaacagaatc agactgcccc agcaaaaacc aatattccta aatggagtaa
    61081 tcctgaatat aaaaatacgt catccgctga ggaattagaa gagatggaac gccaaaccct
    61141 agaattatta gcaaaattag ataacggagg tgattagatg gaaagtgtcg gagatgtact
    61201 caaacgtcaa ccaagtcgtt ttcactatca agatttagtt cagaaaatca tgaaggatcc
    61261 tgatgttgcg gcctttgtcc agcaagaatc cctcaatcag gacgagttga accgtagtat
    61321 ttccaagttt aaccaataca tcactgagag agataaattc ctccgaggag atacagatta
    61381 tattgccaaa ggctacaagc ctatattagt catgaaccat ggctatgcgg atgtttctta
    61441 tgaagaaact cctgaactaa tcgcagctga aaaagaagcg gctatcaaga aacgtctcaa
    61501 cttaattaat tttccatcta gcctgaaaaa tgtcagtttt ttagatgttt atcgtgatga
    61561 tgttcagcgc ttaactgttc taaaaagaat gatagaattt gttaacgatt accccaataa
    61621 tttgaaaggt ctttacttgt atggagactt tggtgtgggt aaaagtttca tggtggctgc
    61681 cctagctcat gatttatcag aaaaacgtgg tgtatcatcc actctcctcc actatcctag
    61741 ctttgtcatt gatgtcaaaa atgctatcag tgatggcaat gttaagacct tggtggatga
    61801 gattaagctg tctgatgtcc tgattttaga tgatattggc gccgagcaat caaccgtttg
    61861 ggtgcgtgac gaaatcctgc aggtcattct ccaatatcgg atgcaggaaa atttaccgac
    61921 ctttttcaca tccaacttca actttgaaga tttggagaag cattttgcga aagtgaaaca
    61981 tggaaatgac gaaacctggg aagccagacg ggtcatggaa cgcatccgtt atttggctga
    62041 ggagactcgt ttagaaggag taaaccgtcg atgacagaaa ccattaaatt gatgaaggct
    62101 catacttcag tgcgcaggtt taaagagcaa gaaattcccc aagtagactt aaatgagatt
    62161 ttgacagcag cccagatggc atcatcttgg aagaatttcc aatcctactc tgtgattgtg
    62221 gtacgaagtc aagagaagaa agatgccttg tatgaattgg tacctcaaga agccattcgc
    62281 cagtctgctg ttttccttct ctttgtcgga gatttgaacc gagcagaaaa gggagcccga
    62341 cttcataccg acaccttcca accccaaggt gtggaaggtc tcttgattag ttcggtcgat
    62401 gcagctcttg ctggacaaaa cgccttgttg gcagctgaaa gcttgggcta tggtggtgtg
    62461 attatcggtt tggttcgata caagtctgaa gaagtggcag agctctttaa cctacctgac
    62521 tacacctatt ctgtctttgg gatggcactg ggtgtgccaa atcaacatca tgatatgaaa
    62581 ccgagactgc cactagagaa tgttgtcttt gaggaagaat accaagaaca gtcaactgag
    62641 gcaatccaag cttatgaccg tgttcaggct gactatgctg gggcgcgtgc gaccacaagc
    62701 tggagtcagc gcctagcaga acagtttggt caagctgaac caagctcaac tagaaaaaat
    62761 cttgaacaga agaaattatt gtagaaagtg agaaattatg gccctaccaa ctattgccat
    62821 tgtaggacgt cccaatgttg ggaaatcaac cctatttaat cggatcgctg gtgagcgaat
    62881 ctccattgta gaagatgtcg aaggagtgac acgtgaccgt atttatgcaa cgggtgagtg
    62941 gctcaatcgt tcttttagca tgattgatac aggaggaatt gatgatgtcg atgctccttt
    63001 catggaacaa atcaagcacc aggcagaaat tgccatggaa gaagcagatg ttatcgtctt
    63061 tgtcgtgtcc ggtaaggaag gaattaccga tgcagacgaa tacgtagccc gtaagcttta
    63121 taagacccac aaaccagtta tcctcgcagt taacaaggta gacaaccctg agatgcgaaa
    63181 tgatatatat gatttctatg ctctcggttt gggtgaacca ctgcctatct catctgtcca
    63241 tggtatcggt acaggggatg tactagatgc gattgtggaa aaccttccaa atgaatatga
    63301 agaagaaaat ccagatgtca ttaagtttag cctgattggt cgtccaaacg ttggaaaatc
    63361 aagcttgatc aatgctatct tgggcgaaga ccgtgttatt gctagtcctg ttgctggaac
    63421 aactcgtgat gccattgata cccactttac agatacagat ggtcaagagt ttaccatgat
    63481 tgatacggct ggtatgcgta agtctggtaa ggtttatgaa aatactgaga aatactctgt
    63541 tatgcgtgcc atgcgtgcta ttgaccgttc agatgtggtc ttgatggtca tcaatgcgga
    63601 agaaggcatt cgtgagtacg acaagcgtat cgcaggattt gcccatgaag ctggtaaagg
    63661 gatgattatc gtggtcaaca agtgggatac gcttgaaaaa gataaccaca ctatgaaaaa
    63721 ctgggaagaa gatatccgtg agcagttcca atacctgcct tacgcaccga ttatctttgt
    63781 atccgctttg accaagcaac gtctccacaa acttcctgag atgattaagc aaatcagcga
    63841 aagtcaaaat acacgtattc catcagctgt cttgaacgat gtcatcatgg atgccattgc
    63901 catcaaccca acaccgacag acaaaggaaa acgtctcaag attttctatg cgacccaagt
    63961 ggcaaccaaa ccaccaacct ttgtcatctt tgtcaatgaa gaagaactca tgcacttttc
    64021 ttacctgcgt ttcttggaaa atcaaatccg caaggccttt gtttttgagg gaacaccgat
    64081 tcatctcatc gcaagaaaac gcaaataaaa aagtagaatc tggaatgaca gttccggatt
    64141 tttttgatat aataaaataa tagaaaacgc tatcaaaaga aagagggtga tgtcggtgat
    64201 ggaacatttg tttaaattct tacttttagc accgtacttt tattttgata actggattga
    64261 gaaggccaac agaaatagta agttttttcc aattttttat tatttttact ggttttacat
    64321 ccccttctat tctcttttta gccttgcttg gacagttgtt tcagttctgt ttttcaatac
    64381 cgtcttgaga aatgtgacag atatcaagtt atggggcatt tggtttcttt ttattctgct
    64441 agctattggt atgaattggt taacttattc ctgtttcaaa gaaatgtttc gcttgagaca
    64501 ggaactaggg aagtctaagg gtggaaggca ttgatttata tcggtttcta tttgtaggag
    64561 gtggccttat ggtacctcta aaatcattta ttacacgcta ttccaaggtt tatattggta
    64621 ataacattta atagaacgaa actaaagaaa acaatttaaa agaggaggtt tgtgatggaa
    64681 cacttgttta aaatgataat cttattaccc tgtttttact ttttcagctg gattgacaag
    64741 gataatagag aaagtaaatt tttcccaatt ttttactatt tttactggat ttacatcacc
    64801 ctctatgctc tttttagcct tgcttggaca gttttttcag ttctgttttt caatatcgtc
    64861 ttgagaaatt tgacagatat caagttatgg ggtatttggc tattattact acttatcgct
    64921 tttgctagtg attggttagc ctatgtcttt ttcaaaaaaa tgcttgactt gagacgggaa
    64981 ctagggaagt ctaaaggcgg aaggcattga tttatactct tcgaaaatct cttcaaacca
    65041 cgtcaacgtc gccttggatt atatatgtaa ctgacttcgt cagtcttatc tacaacctca
    65101 aagcagtgct ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
    65161 tattatatta ctttctattt gtaggaggtg gcttatgaag attcctctct taactttggc
    65221 aaggcataaa tttgtttatg tcttgcttac tttgcttttt cttgctttgg tttatcgtga
    65281 cgttttgatg acttatttct tttttgatat tcatgcgccc gatctagcta aattcgatgg
    65341 acaagcaatt aaaaatgact tattaaaatc agcattagat tttcgtattc tccagttcaa
    65401 tctaggtttt tatcaatcat ttattattcc aatcatcatt gttttgctag gttttcaata
    65461 tattgagctg aaaaataaag ttttacgatt gagtattgga agagaagtga gctatcaagg
    65521 gttaaaaaga aagttgactt tgcaagttgc aagtatccct tgtttgatat atttagtgac
    65581 tgtgctgaca attgcaatta taacctattt ccttgggact ttttctcctc ttggatggaa
    65641 ttctctattt tctgatggaa gtggtttaca aagactccta gatggagaga taaaaagcta
    65701 tttgttcttt acttgtgtcc tactaatcgg tattttcatc aatgcaatct attttttaca
    65761 aatagttgat tatgtgggga atgtgactcg ttcggcaatc acctatttga tgtttctttg
    65821 gcttggttct atgctgctct atagtgcctt gccttactat atggttccta tgacgagttt
    65881 gatgcaagct agctatgggg atgtaagttt gatgaaactc tttactcctt atatccttta
    65941 tattgtccct tatatggtgc ttgaaaaata tgaagataat gtttaagaat tttaacaata
    66001 tttggctaaa gagaaagatc gttttactac ttcgtatagt tctgatgatg attttgataa
    66061 actatctatt gtcaacagcg gttcaaaagc aggatgctgt tatctttttc aagagagaat
    66121 tgatttcaat cttttcctat aatgactatt ctgaagcgaa tttagaaatc cccaaactct
    66181 tgttaaacct ttcgcttttc atggtaggat ggctctctgt cattttactt gaaagtgatt
    66241 tggcagacca ttaccatcac ttgattcgct atcaatcaag ctcctttttc gattatacaa
    66301 ggaaacgatt ggttgtcatt tctaaatttt ttactcaaga tttgtttgtc tggtttcttg
    66361 gtttacttcc gctaggaatt catttcaaaa cagtcgcact tttcttttta cttgctcagt
    66421 taatgatgtt gtacttacta ctgtcttatc tgatagcact gattagtgcg ggcgctggtt
    66481 tttctttttt tctctatttt ttggcatttg tgggacaaga atggatgatg gatcatattg
    66541 taacagtgta tttactactc ttaagtttat tagttatgtt gattgttagt cgcttggaag
    66601 agaaatttaa gaaaggataa acgatgagac ttgaaattat aaatggacag aaaatttatg
    66661 ggaaaagacc tattttaaat cagttgaatt tggtgtttca atcaggaaaa atttatggac
    66721 ttaaaggtga taatggatct ggcaagacgg ttcttttaaa gatacttgct ggttatatta
    66781 agcttgacaa aggaaaagtt cttcaagatg gtaaagttta cggggtaaaa aatcattata
    66841 ttcaggatgc aggaatttta attgaaaaag tcgagttttt atctcattta tccctgagag
    66901 aaaatttgga actgttaagg tatttttcat ctaaagttac ggaaaaaaga attgcctatt
    66961 ggattcaata ctatgattta caggaatttg aagacattga ataccgtcat ttatccttag
    67021 gaacaaagca aaaaatggcc ttgattcaag cctttatttc ctctccttct atactctttc
    67081 tcgatgaacc tatgaatgct ttggatgaga agagtgtgag gttaaccaaa caggtcattt
    67141 tatcttacct gaaaaaagaa aatggtctgg ttatcctgac gtcgcacata tcggaagata
    67201 tttcagacct ttgtacagat gtattagttg tcgaaaatgg acatatacaa atgtaaagga
    67261 tatacaatcc taggagatgg cttatggcac atctaaaatc atttattaca cgctattcta
    67321 aggtctatat tggtttagtt ctgttgatct ggattgcttt cttctttctt ccttggggta
    67381 gtccgattct ggggggggag attgacctct tcagcataca gaaagtcttg ctagtttttg
    67441 gcattctgtc cattttgatg gccttgctgt ccaagaaagt cagtctcttt gtttttggat
    67501 tgatctgctg tctttctctt tggattaact tatttatcct atttgctatt ttgccgattc
    67561 ttggcaatta aagtatcata aaagtcagag aggttagctt ggaaactaac ctctttttcc
    67621 ttttcaaaat ggggattctt ccttgaaaat aatcagtaat tgtgctaaaa ttaaaggaac
    67681 attctaaaat attcggaatt taaagtaagg aaaaacatgg ctaatatttt aaaaacaatt
    67741 atcgaaaatg ataaaggaga aatccgtcgt ctggaaaaga tggctgacaa ggttttcaaa
    67801 tacgaagacc aaatggctgc tttgactgac gaccaactaa aagcaaaaac agttgaattt
    67861 aaggaacgtt atcaaaatgg agaatcactg gattcattgc tttacgaagc atttgcggtt
    67921 gtccgtgaag gtgccaaacg tgtcctaggt ctcttccctt ataaggttca ggtcatgggg
    67981 gggattgttc ttcaccatgg tgacgtgcca gagatgcgta caggggaagg gaaaaccttg
    68041 actgcgacca tgccggtata cctcaatgcc ctttcaggta aaggggttca cgtagttacg
    68101 gttaatgaat acctgtcaga acgtgacgcg actgagatgg gtgaattgta ctcttggctt
    68161 ggtttgtcag tagggattaa cttggctacc aaatctccaa tggagaaaaa agaagcctat
    68221 gagtgtgata ttacttactc aactaactca gaaatcggat ttgactacct tcgtgacaac
    68281 atggtcgttc gcgctgaaaa catggtacaa cgtccgctta actatgcctt ggtcgatgag
    68341 gttgactcta tcttgattga cgaggctcgt acacctttga ttgtatcagg tgccaatgcg
    68401 gttgaaacca gtcagttgta tcacatggca gaccactatg taaaatcttt gaacaaagat
    68461 gactacatca tcgatgtgca gtctaagact attggtttgt ctgattcagg gattgacagg
    68521 gctgaaagct acttcaaact tgaaaacctc tatgacatcg aaaacgtggc tttgacccac
    68581 tttatcgata acgcccttcg tgccaactac atcatgcttc tcgatattga ctatgtggtg
    68641 agcgaagagc aagaaatctt gattgtcgac caatttacag gtcgtaccat ggaaggtcgt
    68701 cgttattctg atggattgca ccaagctatt gaagccaaag aaggtgtgcc aatccaggat
    68761 gaaaccaaga catctgcctc aatcacgtac caaaaccttt tccgtatgta caagaaattg
    68821 tctggtatga cgggtacagg taagactgag gaagaagaat tccgtgaaat ctacaacatt
    68881 cgtgttattc caatcccaac aaaccgtcct gttcaacgta ttgaccactc agaccttctt
    68941 tatgcaagta tagaatctaa gtttaaagcg gttgtcgaag acgttaaggc tcgttaccaa
    69001 aagggtcaac ctgtcttggt tggtacagta gcggttgaaa ctagtgacta catttctaag
    69061 aaattggttg cagctggtgt tcctcacgaa gtcttgaatg ccaaaaacca ctatagagaa
    69121 gcccaaatca tcatgaatgc tggtcaacgt ggtgccgtta ccatcgcaac caacatggcg
    69181 ggtcgtggta ccgacatcaa gcttggtgaa ggtgttcgtg aacttggagg actttgtgtt
    69241 attggtacag aacgtcatga aagtcgtcgt atcgataacc agcttcgtgg acgttcaggt
    69301 cgtcaaggag atccaggtga gtcacaattc tacctatctc ttgaagatga tttgatgaaa
    69361 cgttttggtt ctgaacgctt gaagggaatc tttgaacgct tgaacatgtc tgaagaggcg
    69421 attgagtctc gcatgttgac gcgtcaggtt gaagcagctc agaaacgtgt cgaaggaaat
    69481 aactacgata cccgtaaaca agtccttcaa tacgacgatg tcatgcgtga acaacgtgag
    69541 attatctata ctcaacgtta tgatgtcatt actgcagacc gtgacttggc acctgaaatt
    69601 caggcaatga tcaaacgcac gattggtcgt gtcgttgacg gtcatgcgcg tgctaaacaa
    69661 gatgagaaac tagaggcaat tttgaacttc gctaagtata acttgcttcc tgaagattct
    69721 attacgatgg aagacttgtc aggcttgtct gataaggcca tcaaggaaga gcttttccaa
    69781 cgtgccttga aggtttacga tagtcaggtt tcaaaactac gcgatgaaga agcagttaaa
    69841 gaattccaaa aagttttgat tctacgagtg gtggataaca agtggacaga tcatatcgat
    69901 gcccttgatc aattgcgtaa cgcggttgga cttcgtggct atgctcagaa caaccctgtt
    69961 gttgagtatc aggcagaagg tttccgtatg tttaatgata tgattggttc gattgagttt
    70021 gatgtgacac gcttgatgat gaaagcacaa attcatgaac aagaaagacc acaggcagaa
    70081 cgtcatatca gtacaacagc gactcgcaat atcgctgctc accaagcaag tatgccagaa
    70141 gatttggatt tgagccagat tggacgcaat gaactttgcc catgtggttc tggtaagaaa
    70201 tttaaaaact gtcacggtaa aagacaataa aatgagatag tttagaggcg gatatcttgt
    70261 gaaaagtaaa tttttactgg gtatccgttt gctttataag gagatgagtt atggtattta
    70321 cagcaaaaag ctctaaaata aatatagaag aagttcgtgc cttgtcaaaa ttagaaggtc
    70381 aggctttgga gaggaaatca cagcgagatc aagagctaga agccattata cgtggagaag
    70441 accagcgaat tctcttggta atcgggccat gctcatctga caacgaagaa gctgtccttg
    70501 aatacgctaa gcgtttggca gtcctacaag aagaagtggc agatcgtatc tttatggtta
    70561 tgcgtgttta tactgccaaa ccccgtacca acggagatgg ctataagggc ttgattcacc
    70621 agcctaacgc gacagaagcg cctagtctta tcaatggaat caaagccgtt cgccatcttc
    70681 actatcgtgt catcacagaa acagggatga caactgctga tgaaatgctt tatcctgaaa
    70741 accttccgct tgtagatgat ttgatttctt acatggcagt tggtgcccgt tcagttgaag
    70801 accagcaaca ccgctttgtg gcaagtgggg caggattttc tactggtttt aaaaatccaa
    70861 cctctggaaa tctcaatgtc atgtttaatg ggatttatgc tgctcaaaac aaacaaagtt
    70921 tccttttctt aggaaaagaa gtagaaacaa ctgggaaccc gctttcacac gctattcttc
    70981 gtggtgctct taatgagtat ggaaaaaata ttcccaacta ctattatgac aatttaattg
    71041 ataccattgc ccagtatgag aaaatgggct tggaaaatcc ttttatcatc attgatacca
    71101 atcatgacaa ttctggtaag cagtatattg aacagatccg aattgtccgc cagaccttga
    71161 ttaaccgtgc ttggaatgaa aaaattaagc agttcgttcg tggttttatg attgagtctt
    71221 atctggaaga tggtcgacaa aatgagccag aagtatttgg taagtctatc acagaccctt
    71281 gcctgggttg ggataacaca gaagctcttg tcagagaaat ttacaaaacg ttaggagaat
    71341 aagatggcat ttattgaaaa aggtcaagaa atcgatatgg aagtcatcaa ggctgaaacc
    71401 caattgtctg cggaagcctt gagactcaag gaaagccgtg acagggaatt ggcagatatt
    71461 atttcagggg aagatgaccg tattctcttg gtgattggtc cttgctcttc tgataatgaa
    71521 gaggcggtct tggaatatgc tcgccgttta tctgccttgc aaaagaaggt agcggataag
    71581 attttcatgg tcatgcgcgt gtatactgct aagcctcgta ccaatggaga cggctataaa
    71641 ggattggttc accagccaga tacttctaag gctccaagcc tgattaacgg cttgcaggct
    71701 gtgcgccagt tgcactaccg cgtgattaca gagactggtt tgacaacggc agatgagatg
    71761 ctttatccgt caaatctgat cttggtggat gacttggtca gctaccatgc cgttggagct
    71821 cgttctgtgg aagaccagga gcaccgcttt gtggcttctg ggattgatgc accagtaggg
    71881 atgaaaaatc caacctcagg aaatttgggt gttatgttta acgccatcta tgctgctcaa
    71941 aacaagcaaa ccttccttta tcatgggcag gaagttgaga catcaggtaa tcctttggcc
    72001 catgttatcc tccgtggagc agtcaacgag tatggcaatt atatgccgaa ttactactat
    72061 gaaaacctac tccaagccat tgaacgctat gaaaccatgg gacttgaaaa tccttttatc
    72121 ctcattgaca ccaaccatga taactcaggc aagcaatata tggagcagat tcgaattgtt
    72181 cgccagacct tgcagaatcg tgattggaat gagaaaatta aaaagacggt tcgaggattt
    72241 atgattgaat cttacctagc agatggtcgt caaaaccaac cagagatctt tggttgctct
    72301 attactgacc cttgcctagg ttgggaaaat acagaggcct tggtagaaga gatttatgtt
    72361 accttgacaa aataagtgaa aaggatggag ttggggaatc tcaactcctt ttgatgagaa
    72421 tgatagttgg acacggaatt gacatcgaag aattggcttc gatagaaagc gcagttacac
    72481 gacatgaagg atttgctaag cgtgtactga ccgctcagga aatggagcgc ttcaccagtc
    72541 tcaaaggacg caggcaaata gaatatttag ctggtcgctg gtcggctaag gaggcctttt
    72601 ccaaggctat gggaacgggc attagcaagc tcggttttca ggatttggaa gtcttgaaca
    72661 atgaacgtgg ggcgccttat tttagtcagg caccattttc aggaaagatt tggctgtcta
    72721 tcagccacac cgatcagttt gtgatagcca gtgtcatttt ggaggaaaat catgaaagct
    72781 agtccacata gaccaaccaa ggctctgatt catctgggag ctattcgaca aaatattcag
    72841 caaatggggg ctcatatccc tcaaggaacg ctcaagttgg ctgtggtcaa ggccaatgct
    72901 tatggtcatg gagctgttgc cgttgccaag gcaattcaag atgatgttaa tggcttttgc
    72961 gtttccaata tcgatgaagc cattgaactc agacaagctg gactcagcaa gccaatcctc
    73021 attttaggag tttctgaaat cgaagctgtt gctctagcta aagaatatga cttcaccttg
    73081 acagtggctg gactggagtg gattcaagca ctcttagata aggaagtgga cctaactgga
    73141 ttgacagtcc acctcaagat tgattcaggg atgggacgga ttggttttag agaggccagt
    73201 gaggttgagc aggctcaaga tttgctccaa caacacggtg ttcgtgttga aggaatcttt
    73261 acccactttg ctactgctga tgaggaatca gatgactatt ttaatgccca gttagaacgg
    73321 tttaaaacta ttttagctag tatgaaggaa gttccagagc tggttcatgc tagcaattct
    73381 gcaacgactc tttggcatgt agagactatt ttcaatgcgg ttcgtatggg agatgccatg
    73441 tatggcctca atccaagtgg agcggtcttg gatttgcctt atgatttgat accggccttg
    73501 accttggagt ctgctctggt tcatatcaag acagttccag ctggtgcttg catgggctat
    73561 ggagcaactt atcaagcgga tagcgagcaa gtcatcgcga ccgtgccaat cgggtatgca
    73621 gatggatgga caagagacat gcaaaatttc tctgtcttgg tagatggcca agcttgccca
    73681 attgtcggca gggtttcgat ggaccaaatc actattcgat tgcctaagcc ttacccactc
    73741 ggaaccaagg taaccttgat tggctccaat ggggataagg aaatcactgc aactcaggta
    73801 gcgacctacc gcgtaaccat taactatgag gtggtttgcc tcctcagcga ccgtattccg
    73861 agagaatatt attagaaaag aaaggagtgg agcatgaatc tacatcaacc cttgcatgtc
    73921 ttgcctggtg tgggaccaaa gtcagcagaa aaatacgcca aactaggaat tgaaaacttg
    73981 caagatctct tgctctactt tcctttccgt tatgaagact tcaaaaccaa gcaggtgctg
    74041 gagctggaag acggtgagaa ggcagttctt tctggtcagg tagtgactcc tgctagtgtc
    74101 cagtattatg gtttcaagcg caatcgcctg cgttttagtc tcaagcaggg agaggtcgtt
    74161 tttgcggtga atttctttaa ccagccctat ctggctgata aaatagagtt gggagcaacc
    74221 cttgctgtct ttggaaaatg ggaccgcgct aaggctagtc tgactgggat gaaggttctg
    74281 gctcaggtag aagatgacct ccagcctgtc tatcgtctgg ctcagggaat cagtcaggcc
    74341 agtctggtca aggtcatcaa gacggctttt gatcagggac tggacctctt gatagaagaa
    74401 aatctgcccc agtctttact agacaaatac aaactcatgt cccgttgtca ggcagtccga
    74461 gctatgcatt ttccaaagga tttggcagaa tacaagcagg ctcttcgccg tatcaagttt
    74521 gaggaactct tttatttcca aatgcagctg cagacgctca agtctgaaaa tagagttcag
    74581 ggaagtggtc tggttctgga ttggtctcag gaaaaagtga cagcagttaa agcaagtctt
    74641 ccttttgccc tgacccaagc tcaggaaaag agtttgcagg aaattttaac tgatatgaag
    74701 tccgaccacc acatgaatcg tctcctacaa ggagatgtgg ggagtggaaa aacggtagtc
    74761 gctggcttgg ccatgtttgc ggcagtgaca gcaggttatc aggctgccct aatggtacca
    74821 acagaaatcc tcgcagagca acactttgag agtttacaga acctttttcc caatttgaaa
    74881 ctggctctct tgacaggttc cttgaaagct gcagaaaaga gagaagtctt ggagaccatt
    74941 gccaagggtg aggctgattt gattatagga actcacgctc tgatacaaga tggggtggag
    75001 tatgctcgtc ttggtttgat tattatcgat gagcagcacc gttttggtgt agggcaaagg
    75061 cgtattttac gggaaaaagg tgacaatcca gatgtcctca tgatgacggc gactcccatt
    75121 ccacggacgc ttgccatcac agcctttgga gatatggatg tttccattat cgaccagatg
    75181 ccagcaggtc ggaagcctat tgtgacgcgc tggatcaaac atgagcaact acctcaggtc
    75241 ttgacttggt tagaggggga aattcaaaaa ggttcccaag cctatgtcat ctctcctttg
    75301 attgaagaat cagaagctct agatttgaaa aatgccattg ccttatcaga ggagttgacg
    75361 actcattttg caggcaaggc agaggtggct cttctacatg gtaggatgaa gagtgacgaa
    75421 aaagaccaga tcatgcagga tttcaaggag agaaagacgg atattctggt ttcgacgacg
    75481 gttattgagg ttggggtcaa cgttcccaat gcgactgtca tgattatcat ggatgccgat
    75541 cgcttcggtc tcagtcaact tcaccagctt agaggtcgtg tcggtcgggg ggacaagcag
    75601 tcctacgctg ttctcgttgc caatcccaag acggattctg ggaaagaccg catgcgcatc
    75661 atgacagaaa cgaccaatgg atttgtcctt gcggaggaag atttgaaaat gcgtggttct
    75721 ggtgagattt ttggaaccag acagtcagga cttccagagt tccaagtggc tgatattatc
    75781 gaagattttc cgattttaga agaagcaaga aaggttgcta gctacattag ttctatagaa
    75841 gcttggcaag aagatccaga gtggcgcatg attgcccttc atctggaaaa gaaagaacat
    75901 ctggattaag ctttctctaa ggaaaactta agctagtttt taggtttggc tcttatacta
    75961 aagtcatcaa aaagaaacga ggactctcat atgacagtaa cgattaaagt aaattaccaa
    76021 accactttcc aaaagaagga agcaaaaaac tagtataaac agaagagaga gcgaaatgct
    76081 ctttttcgtt tctaaaacta ctttcagccc atcatcctaa aagtaaagaa tctaaattca
    76141 ctttctattt atccttcttt cttgcattga ttacatagat atgctacagt tgtggtaacg
    76201 attacaaaat aaaaggagca tgctatgaaa aatccagctt tgctagaaga aattaagacc
    76261 tatagaggaa gggatgaggt tccggaagac tttgatgctt tctgggatgg ggaagtgaaa
    76321 aatgtttcca cgcttccatc ctaccacttg gaggaaagag atttccacat tcctcaagtc
    76381 aagtgctatg agttaacatt tgaaggaagc aaggaaggaa aggtctatgc acgcattgtt
    76441 cttccaaaga gtgaggagaa ggttccacta atcttccatt ttcatggtta tatgggacgt
    76501 ggctgggact gggccgacat gctgggcttc accgtagctg gttacggtgt tgtttccatg
    76561 gatgtgcggg gccagtcagg ttactcacaa gacggcttgc gttctccttt aggaaatacc
    76621 gtgaaggggc atattatccg tggtgctatg gaaggtcggg accacctctt ttataaggat
    76681 gtttatctgg atatttacca gttggtcgaa attgttgcta gtctgtctca ggttgatgag
    76741 aagcgtcttt ctagctatgg tgcctcacaa ggaggggctc tagctctagt tgcagcagcg
    76801 ctcaatcctc gaattcagaa aacagttgcc atttatccct tcttgtcaga cttcagacgg
    76861 gtgattgaga ttggtaatac tagcgaggct tacgacgaac ttttccgtta tttcaagttt
    76921 cacgacccct tccatgaaac agaggaggaa atcatggcga cccttgccta tatcgatgtc
    76981 aaaaatcttg cccatcgtat ccaaggtgag gttaagatga ttacgggctt ggacgacgat
    77041 gtttgctatc ccattaccca gtttgcgatt tataatcgtc tgacctgcga taaaacctat
    77101 cgtatcatgc ctgagtatgc tcacgaaacc atgaatgtat ttgtcaatga ccaagtctac
    77161 aactggctct gtggaagtga gattcctttt aaatatctaa aataaggagt cgactctaag
    77221 cacaaaatct taaaaattac aaacacgcat agtatcaggg gattaagaaa acttgatact
    77281 atgcgtttta tcatggaaat atagtaaaat gaaacaagaa caggacaaat cgatcaggac
    77341 agtcaaatcg atttctaaca atgttttaga agtagatgtg tactattcta gtttcaatct
    77401 attatattta tagaattttt tgttgctaga tttgtcaaat tgcttaaaat aatttttttc
    77461 agaaagcaaa agccgatacc tatcgagtag ggtagttctt gctatcgtta ggcttgtctg
    77521 taggtgttaa tacttttcaa aaatctcttc aaaccacgtc agcttcgcct tgccgtaggt
    77581 atggttactg acttcgtcag ttctatccac aacctcaaaa c
//
LOCUS       DAVMBH010000004        75217 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVMBH010000004 DAVMBH010000000
VERSION     DAVMBH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75217
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.004"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..2333)
                     /locus_tag="VYP30_000293"
     CDS             complement(<1..2333)
                     /locus_tag="VYP30_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1807349.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTETHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFD"
     gene            complement(2580..2948)
                     /gene="rplL"
                     /locus_tag="VYP30_000294"
     CDS             complement(2580..2948)
                     /gene="rplL"
                     /locus_tag="VYP30_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1807350.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(3024..3524)
                     /locus_tag="VYP30_000295"
     CDS             complement(3024..3524)
                     /locus_tag="VYP30_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1807351.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVAFAVKAVAE
                     SKEDAA"
     misc_feature    complement(3563..3698)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3774..5033)
                     /locus_tag="VYP30_000296"
     CDS             complement(3774..5033)
                     /locus_tag="VYP30_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1807352.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(5290..7038)
                     /locus_tag="VYP30_000297"
     CDS             complement(5290..7038)
                     /locus_tag="VYP30_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807353.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSLVFWQIFLHMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLDIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(7040..8764)
                     /locus_tag="VYP30_000298"
     CDS             complement(7040..8764)
                     /locus_tag="VYP30_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807354.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKLELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQVTSDRVLQV
                     QELTFTYPDAAQPSLRDISFDMIQGQILGIIGGTGSGKSSLIQLILGLYPVNKGRIDL
                     YLDGLSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     ILKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHEKED"
     gene            complement(8822..9760)
                     /gene="msrB"
                     /locus_tag="VYP30_000299"
     CDS             complement(8822..9760)
                     /gene="msrB"
                     /locus_tag="VYP30_000299"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1807355.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(9947..10024)
                     /locus_tag="VYP30_000300"
                     /pseudo
     CDS             complement(9947..10024)
                     /locus_tag="VYP30_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10100..10969)
                     /locus_tag="VYP30_000301"
     CDS             complement(10100..10969)
                     /locus_tag="VYP30_000301"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1807356.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(10971..12257)
                     /locus_tag="VYP30_000302"
     CDS             complement(10971..12257)
                     /locus_tag="VYP30_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1807357.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(12408..13145)
                     /gene="mecA"
                     /locus_tag="VYP30_000303"
     CDS             complement(12408..13145)
                     /gene="mecA"
                     /locus_tag="VYP30_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1807358.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(13345..14379)
                     /locus_tag="VYP30_000304"
     CDS             complement(13345..14379)
                     /locus_tag="VYP30_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1807359.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(14408..15841)
                     /locus_tag="VYP30_000305"
     CDS             complement(14408..15841)
                     /locus_tag="VYP30_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1807360.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRIILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMFTKEN"
     gene            complement(15857..16843)
                     /locus_tag="VYP30_000306"
     CDS             complement(15857..16843)
                     /locus_tag="VYP30_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1807361.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFKAYS
                     QIHRFLKDHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(16845..17948)
                     /locus_tag="VYP30_000307"
     CDS             complement(16845..17948)
                     /locus_tag="VYP30_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1807362.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(17938..18783)
                     /locus_tag="VYP30_000308"
     CDS             complement(17938..18783)
                     /locus_tag="VYP30_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1807363.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(19062..20336)
                     /gene="psr"
                     /locus_tag="VYP30_000309"
     CDS             complement(19062..20336)
                     /gene="psr"
                     /locus_tag="VYP30_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1807364.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLRIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(20333..21181)
                     /gene="pheA"
                     /locus_tag="VYP30_000310"
     CDS             complement(20333..21181)
                     /gene="pheA"
                     /locus_tag="VYP30_000310"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1807365.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(21178..21654)
                     /locus_tag="VYP30_000311"
     CDS             complement(21178..21654)
                     /locus_tag="VYP30_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1807366.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(21647..22930)
                     /gene="aroA"
                     /locus_tag="VYP30_000312"
     CDS             complement(21647..22930)
                     /gene="aroA"
                     /locus_tag="VYP30_000312"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1807367.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(23022..23360)
                     /locus_tag="VYP30_000313"
     CDS             complement(23022..23360)
                     /locus_tag="VYP30_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1807368.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(23371..24474)
                     /locus_tag="VYP30_000314"
     CDS             complement(23371..24474)
                     /locus_tag="VYP30_000314"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1807369.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNARDLERAEHLITENTDYTVVIK"
     gene            complement(24484..25650)
                     /gene="aroC"
                     /locus_tag="VYP30_000315"
     CDS             complement(24484..25650)
                     /gene="aroC"
                     /locus_tag="VYP30_000315"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1807370.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLVELDVEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(25660..26727)
                     /locus_tag="VYP30_000316"
     CDS             complement(25660..26727)
                     /locus_tag="VYP30_000316"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1807371.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(26746..27600)
                     /locus_tag="VYP30_000317"
     CDS             complement(26746..27600)
                     /locus_tag="VYP30_000317"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1807372.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWIGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(27590..28267)
                     /locus_tag="VYP30_000318"
     CDS             complement(27590..28267)
                     /locus_tag="VYP30_000318"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1807373.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(28264..29427)
                     /locus_tag="VYP30_000319"
     CDS             complement(28264..29427)
                     /locus_tag="VYP30_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1807374.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDREVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLNY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASHTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(30112..31746)
                     /locus_tag="VYP30_000320"
     CDS             complement(30112..31746)
                     /locus_tag="VYP30_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807375.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENLDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVKRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(31727..32476)
                     /locus_tag="VYP30_000321"
     CDS             complement(31727..32476)
                     /locus_tag="VYP30_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807376.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            32655..34109
                     /locus_tag="VYP30_000322"
     CDS             32655..34109
                     /locus_tag="VYP30_000322"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1807377.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANKELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(34199..36817)
                     /gene="alaS"
                     /locus_tag="VYP30_000323"
     CDS             complement(34199..36817)
                     /gene="alaS"
                     /locus_tag="VYP30_000323"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1807378.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVDNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAIAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(36839..37324)
                     /locus_tag="VYP30_000324"
     CDS             complement(36839..37324)
                     /locus_tag="VYP30_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1807379.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(37599..37838)
                     /locus_tag="VYP30_000325"
     CDS             complement(37599..37838)
                     /locus_tag="VYP30_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807380.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(38099..39169)
                     /locus_tag="VYP30_000326"
     CDS             complement(38099..39169)
                     /locus_tag="VYP30_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1807381.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(39166..39939)
                     /locus_tag="VYP30_000327"
     CDS             complement(39166..39939)
                     /locus_tag="VYP30_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807382.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(39936..40742)
                     /locus_tag="VYP30_000328"
     CDS             complement(39936..40742)
                     /locus_tag="VYP30_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807383.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(40723..41880)
                     /locus_tag="VYP30_000329"
     CDS             complement(40723..41880)
                     /locus_tag="VYP30_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807384.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(41939..42889)
                     /gene="murB"
                     /locus_tag="VYP30_000330"
     CDS             complement(41939..42889)
                     /gene="murB"
                     /locus_tag="VYP30_000330"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1807385.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(43001..43753)
                     /locus_tag="VYP30_000331"
     CDS             complement(43001..43753)
                     /locus_tag="VYP30_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1807386.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(43763..44494)
                     /gene="budA"
                     /locus_tag="VYP30_000332"
     CDS             complement(43763..44494)
                     /gene="budA"
                     /locus_tag="VYP30_000332"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1807387.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            44636..45907
                     /locus_tag="VYP30_000333"
     CDS             44636..45907
                     /locus_tag="VYP30_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1807388.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(45927..46742)
                     /locus_tag="VYP30_000334"
     CDS             complement(45927..46742)
                     /locus_tag="VYP30_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1807389.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVDAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQVGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKNEGTYQSYLEKAASLTEVEE"
     gene            complement(46899..47552)
                     /gene="phoU"
                     /locus_tag="VYP30_000335"
     CDS             complement(46899..47552)
                     /gene="phoU"
                     /locus_tag="VYP30_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1807390.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(47564..48322)
                     /gene="pstB"
                     /locus_tag="VYP30_000336"
     CDS             complement(47564..48322)
                     /gene="pstB"
                     /locus_tag="VYP30_000336"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1807391.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(48335..49138)
                     /gene="pstB"
                     /locus_tag="VYP30_000337"
     CDS             complement(48335..49138)
                     /gene="pstB"
                     /locus_tag="VYP30_000337"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1807392.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(49149..50033)
                     /gene="pstA"
                     /locus_tag="VYP30_000338"
     CDS             complement(49149..50033)
                     /gene="pstA"
                     /locus_tag="VYP30_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1807393.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(50023..50940)
                     /gene="pstC"
                     /locus_tag="VYP30_000339"
     CDS             complement(50023..50940)
                     /gene="pstC"
                     /locus_tag="VYP30_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1807394.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(50940..51818)
                     /gene="pstS"
                     /locus_tag="VYP30_000340"
     CDS             complement(50940..51818)
                     /gene="pstS"
                     /locus_tag="VYP30_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1807395.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(52392..53696)
                     /locus_tag="VYP30_000341"
     CDS             complement(52392..53696)
                     /locus_tag="VYP30_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1807396.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDVMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(53697..54470)
                     /locus_tag="VYP30_000342"
     CDS             complement(53697..54470)
                     /locus_tag="VYP30_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1807397.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSSTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(54460..54738)
                     /locus_tag="VYP30_000343"
     CDS             complement(54460..54738)
                     /locus_tag="VYP30_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1807398.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(54738..55139)
                     /locus_tag="VYP30_000344"
     CDS             complement(54738..55139)
                     /locus_tag="VYP30_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1807399.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(55349..55966)
                     /locus_tag="VYP30_000345"
     CDS             complement(55349..55966)
                     /locus_tag="VYP30_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1807400.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(55956..56729)
                     /locus_tag="VYP30_000346"
     CDS             complement(55956..56729)
                     /locus_tag="VYP30_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1807401.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(56740..57477)
                     /locus_tag="VYP30_000347"
     CDS             complement(56740..57477)
                     /locus_tag="VYP30_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1807402.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(57482..58612)
                     /locus_tag="VYP30_000348"
     CDS             complement(57482..58612)
                     /locus_tag="VYP30_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1807403.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(58696..59085)
                     /locus_tag="VYP30_000349"
     CDS             complement(58696..59085)
                     /locus_tag="VYP30_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1807404.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIHITEE"
     gene            complement(59101..59484)
                     /locus_tag="VYP30_000350"
     CDS             complement(59101..59484)
                     /locus_tag="VYP30_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1807405.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(59485..60273)
                     /locus_tag="VYP30_000351"
     CDS             complement(59485..60273)
                     /locus_tag="VYP30_000351"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1807406.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(60266..61201)
                     /locus_tag="VYP30_000352"
     CDS             complement(60266..61201)
                     /locus_tag="VYP30_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1807407.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(61331..61507)
                     /locus_tag="VYP30_000353"
     CDS             complement(61331..61507)
                     /locus_tag="VYP30_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1807408.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(61647..62354)
                     /locus_tag="VYP30_000354"
     CDS             complement(61647..62354)
                     /locus_tag="VYP30_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1807409.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            62505..63533
                     /gene="queA"
                     /locus_tag="VYP30_000355"
     CDS             62505..63533
                     /gene="queA"
                     /locus_tag="VYP30_000355"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1807410.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGSHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQRIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(64082..65209)
                     /locus_tag="VYP30_000356"
     CDS             complement(64082..65209)
                     /locus_tag="VYP30_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1807411.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGSIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(65925..66476)
                     /locus_tag="VYP30_000357"
     CDS             complement(65925..66476)
                     /locus_tag="VYP30_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807412.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(66723..67547)
                     /gene="nadE"
                     /locus_tag="VYP30_000358"
     CDS             complement(66723..67547)
                     /gene="nadE"
                     /locus_tag="VYP30_000358"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1807413.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(67544..69004)
                     /locus_tag="VYP30_000359"
     CDS             complement(67544..69004)
                     /locus_tag="VYP30_000359"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1807414.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(69120..69608)
                     /locus_tag="VYP30_000360"
     CDS             complement(69120..69608)
                     /locus_tag="VYP30_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807415.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(69598..69807)
                     /locus_tag="VYP30_000361"
     CDS             complement(69598..69807)
                     /locus_tag="VYP30_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807416.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(70192..70920)
                     /locus_tag="VYP30_000362"
     CDS             complement(70192..70920)
                     /locus_tag="VYP30_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807417.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(70936..71727)
                     /locus_tag="VYP30_000363"
     CDS             complement(70936..71727)
                     /locus_tag="VYP30_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807418.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQEIFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLSVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLSITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(72163..72891)
                     /locus_tag="VYP30_000364"
                     /pseudo
     CDS             complement(72163..72891)
                     /locus_tag="VYP30_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(73151..73462)
                     /locus_tag="VYP30_000365"
     CDS             complement(73151..73462)
                     /locus_tag="VYP30_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807419.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(73477..74763)
                     /locus_tag="VYP30_000366"
     CDS             complement(73477..74763)
                     /locus_tag="VYP30_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1807420.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
BASE COUNT        22488 a        16744 c        13755 g        22230 t
ORIGIN      
        1 tcatcaaaaa caatcggtaa attttctttc acttcggctt tatgcaaagc ataaactatt
       61 ttttctccaa tcatagataa gtttttaatg tcattaaaaa ataatttcct aatatttctc
      121 aaatctccaa agatagtatt acgatgactt tctgaatagg tcaaaatttt tcttctgtaa
      181 tcatatagca ttttctcaat ataaaatcta gtttcacaac tccctatatt atacaaattc
      241 gctaaaagtt ttagtatact tctatgatac tgttttaatt tttcactatc cgggacttta
      301 tagcgcccaa aagtaaattt ctcttcatga gtctctgttc tttcgatttc aattttaaga
      361 aactgcttca aaattgtcac gattaattct tggttataac ttttcgtcaa atcaagatta
      421 gcaagttcag aaatggtatt ttcagctaag gtataatcaa tatattctct ttctgtaacc
      481 aacccgtagt ttgcttcaag aatactataa acctcagaaa ttttattagg atttttatca
      541 aagtacttta acaataattg gagaatttga ctacaatatt ttgtccgtgt agttacaaat
      601 acaatattta aaactgaatc ctcaatagat ccctttttat ccttctgatt aataaaatta
      661 gtctttgtat aaacctgaga ctctatatta tcaattttat ttttaacgtg tgaaattgct
      721 tctaaaggaa gtaatactcc aaattgtatt aaaaactttt ctttaagttc atcactttca
      781 aaattacttt cattgtaata atatgattta actgcatcag aaacgccttc taaatcactc
      841 tctttcctaa taaaattgga acattgattt agtatttgaa caactctttg gtcgtttact
      901 ggatataact catgtaaaat ttctaaaatt gatattttct tgttaattaa aaacttgata
      961 actatataat catctaatga ttgatctgct atctttacaa ttttgtcgtt ataaatatta
     1021 cacaactctc tttcatgaag cttctccact gcactcttaa agtcagtatt tgttatgtca
     1081 gttattttta gtaatttatt gaattcctgg ttctcttcta aactttccag tctaatcttt
     1141 tttaagtaag ataaaataaa tagagtcttt tgttctgcat aaataatgtt gtttttattt
     1201 aaaatttctt catagtaatc ttttaaaata tcaatctcat cattaaaatt agtcaaatcc
     1261 tgagagctag ataactttgc tgcaatgact gcaatacgcg gattgctttt agatatcgtt
     1321 tttatatgtt caatttcttg attggtaaaa tcgtttcgag aaaattgatt gagtaattcc
     1381 ttaaaattat catcttttat aagttctggc tcaatattat tgtacccata aactttaata
     1441 ttattgatta catctttttt agcataatca cgtaccgtaa gaataaaccg aatattacta
     1501 gtcgtgttca gtagcccaag tgtagaaata taattttgtg tagtattaac atcatcaata
     1561 aaaacaatat tttctttgtg taaatttaga ttgcgtttta catcttggta aatatcctga
     1621 ttattgctct tgacacaaat aatgttatat ttatttcgat ccagcaaaga gcaaatttca
     1681 attgctaatc tagttttccc tgttccaggc ttagcagata ttaagaagat tcgtttttca
     1741 cttgatttaa tggtatttat aatttcactt acatctccaa tatagtcatt tgatatagga
     1801 gcattagttt tactctcatc atgaattctt atgaagtcat tgatagacca aacttgctct
     1861 gtagattcac tgattgatag atactctttt gctaaatatt gaaaatctat ctttgtaaga
     1921 tcattagcaa tttcattaat tccaatcaat tctagatgat aaggctcagc cattttttct
     1981 agatcttctt tttgtttaat tgttatattt gaagaagtat gacaacaaat aagtctccca
     2041 actttatctt cagcaatatt ttcctctaaa atttttttct taactgactg aatgtctcct
     2101 tctaatttag atattacaga cttatgggtg ccatacataa tataaacata tttaccattt
     2161 tcgacagcgt aagaatctgg gatcccttta gttgttttat ctgttccttc ctgtgagcct
     2221 aatgaaacaa tattaaaatt gtattttcta cttaggtacg cgtcacctag tttttgaaac
     2281 ttccctccct ctagctcttt aatatgttgc tcaattttat ttcttaaact cattataaaa
     2341 acctttccag ataagtattt caacataatt atatcacact agtcaaaacc ataaggtata
     2401 gtttaattaa caaactcttg tactacgtta atttagagta gtaaaccaat tatacaaaaa
     2461 ttatttattt cctaaacaac tatataaaaa gtttgcccct ttttaaacaa aaagaaaaac
     2521 cgctactcct aagaatagcg gtttaatcat gtttttaagc tactaatgta gttgctctat
     2581 tatttaagag taactgaagc tccagcttct tccaatttag ctttgatttc ttcagcttct
     2641 gcagttgcaa cgccttcttt aacaagtgct ggtgcaccgt caacaagttc tttagcttct
     2701 ttaagaccaa gaccagtgat ttcacgtaca actttgataa cgccaacttt tttgtcgcct
     2761 gcagatgtca attcaacgtc gaatgaatct ttagcagcac cagcatcagc tgcatcagct
     2821 gcagcaacag ctacaggagc agctgcagtt acaccaaatt cttcttcgat agcttttaca
     2881 aggtcgttca attcaaggat tgaagcttct ttaatttcag caataatgtt ttcaatgttc
     2941 aatgccattg ttatttcctc caaataagtt ttaaatttta taatagtttt tttcgtagct
     3001 aggctacgct gtgtagctta agattaagcc gcgtcttctt tgctttctgc aaccgctttg
     3061 actgcaaaag caacgttgcg cactggcgct tgaagtacag aaaggagcat agaaagaagt
     3121 ccttcgcggt ttggaagagt tgcaagtgca agaatctctt ctttagatgc gacagcgcct
     3181 tcgattgcac cacctttaat ttcaagtgct tcagcgtttt tagaaaagtc gttcaagatt
     3241 ttcgctggtg cgataacatc ttcattagaa aatgctactg cagatggtcc aacaaataca
     3301 gatgcaagat cttcaagacc agctttttca gctgcacgac gcaagattga gtttttaata
     3361 actttatact caacttcgct tccacgaagc tcacgacgaa gaactgtatc ttgctcaact
     3421 gtcaaaccac gagcgtctac aacgacgata gatgcagcag ctttcatttt ttcagctact
     3481 acgtcaacta gttccgcttt tttagcaata attgcttcac tcattagtgt gttcacctcc
     3541 gtaattattt tgcttgggga atttttcaaa aagaaaaacg cgcccaaacc tagacacgaa
     3601 agtacaatac gcttcttttt acatgatacg ttttgtcctc ggtaggatat ttatgagtcg
     3661 agctccccta ctgtcttagg cagttttttt aaaccgtata taagtatagc atagtcaaaa
     3721 aaagaatgca agatttttgc aaactttttt taaaattttt cgtaattttt cttttaaagt
     3781 tctactgtca ggacttgacc ttgcttaaca acctgttctc cggcgatata aacatcatct
     3841 acatcactag atttaactgc ataaaccagg tgagacagca tattttcctg aggttggaga
     3901 tgaattttcc cttgtggttg aatgaccaga aaatctgctt gcttgccgac ttccagactt
     3961 cctatctgat tttccattcc aaggacctta gccccttcga ttgtcagtac cttgagagct
     4021 gtttcgattg gaaactggct ggcatcccca cttttcatct tctgaagaag agctgcagtc
     4081 cttccttcct caaacatatc tagattgtta ttggaagcaa ccgagtcagt cgcaattccg
     4141 actgctactc ccgctttttg gagctggata attggagcaa ttcctgatgc cagtttgagg
     4201 ttactgatag gattgtgggc gatagccact tgagaagatg ccaagcgttc aatttctctc
     4261 tcgtttaatt cgaccccgtg agcaaatacg gacggatgat ctaaataacc cagttcttca
     4321 agaaaagcaa gggggcgttt gccgtatcgt ttgaggataa ttcctgactc ctccttggtc
     4381 tccgccacat ggacatggag cggaatattt agctcttttg ccatttccaa actcgcttcc
     4441 agcaagtctc tactgcagct atacggagaa tgaggtgcta ccataacctt gaaatttgga
     4501 tttttatatt ttaagatttc atctatgatg gatcgagttc tgcttatagt ctcagcagtt
     4561 gtttctgtct ctgaagaaaa gagagtcgga gaaaaataac aacgcatctt ggaagttttc
     4621 accacctgat aaatttgctg gatatccaca ccaatgggat tatacatatc gttaaaggtt
     4681 gttgttcctg actggagcat ctctgtcagg gcttctttga ccgcattggt agtcatgtcg
     4741 ggagtaaact cagattctgc tggccaaata tagtcattga gccattcatg gagattgctg
     4801 tcatctcgga tccctctcag acctgtcatt gcagaatggg tgtgacaatt gaccaaacca
     4861 ggcataatcc aagctccctg atagtctata atctgctcag cttgctctaa aaacgctggc
     4921 ttatcttgac cgacatagac gatttgagaa tccttgactg ctaagattcc atcaagataa
     4981 acatggaaat cttgatcaca agtcacgata tttacatgct gaaagacttt cattataggc
     5041 tccttttcta aaagacaagt tgtactctct tcaaaccact tcagattcac tttgccgtag
     5101 gtgtggttac tgacttcgtc agttctatct gcaacctcaa agctgtgctt tgagcaacct
     5161 acggctagct tcctagtttg ctctttgatt ttcattgagt attacagtga acaatttttc
     5221 tagctattgt aacaaaaaag tcactcgaag gcaacttttt tcgtccataa actttcaaaa
     5281 gagaatggct tattcagaac taaaagccgc agctttttgc atttggtaat acttaccctt
     5341 tctatccatg agttcttgat ggttaccata ttcaacaata tcaccatcta ctaagacaag
     5401 aattaaatcc gcatcctgaa tggttgacaa acggtgagca atgatgaaac ttgtgcggcc
     5461 cttcatgagt tttgcaaagg catcctgtac cagcacttct gtccgtgtat caatggaaga
     5521 agttgcctcg tctaagataa gaatctttgg aatatccaga aagactcggg ctatggtcaa
     5581 gagctgagct tggccgacag agagagattc tccagcattt tccaacttgg tatcgtatcc
     5641 ctgtggcaac tgttggatga aaaagtctgc attagctgct ttggcagcag caattacttg
     5701 ctctcgactg gcttcaggat tgccaaaggc aatattatca tgaatggtcc cttgtgtgag
     5761 ccaggtttct tgaagcacca taccaaactg ctgtctcaat gatactcgtg tataatcata
     5821 aatggattgc ccatccagca agatatctcc cgagctaatg ggataaaaac gcataaggag
     5881 attgataaga gttgattttc cagcacctgt cggaccaacg atggctacct tactaccagc
     5941 tggaatatcg atagacaact ccttaatcaa aattttttca ggatggtagc caaaagagac
     6001 atgtttaaag gaaatagctc ccttaacttg gtcactggtc aagacttcct tacctgtttc
     6061 agccacttca gggctatcta aaactccata gatacgctct acgcaagcca gagcactttg
     6121 caactcagct agcactgaag aaatatcgtt aaagggcttg gtgtattgct gaacatagtt
     6181 caaaaaagtc actaaacgac cgacggtcaa ggttgaaccc atcatgatac gataagctcc
     6241 tactccagct aaaagagcat aaatgagtgc atttacaaag cgagtcgaag gattgaccgt
     6301 tgaagaataa aagatggctg actgagaata gcctgagtag ttgtcatgag cctcacgcaa
     6361 tctttggata aattctgttt gagcattgaa ggactggatt atagtctgct ggctaagcga
     6421 ttcttcaatc aactgagtct gaattcccct cgtctctgtt tgcttctgga agagatgata
     6481 ggatctcttg gcaataaagc gtgaaatcac catggacagt ggcgtcaaca gcaagactaa
     6541 gagagtcatg aggagatgaa tttggagcat ggctagaata ctaaccaaaa tcatcaaaac
     6601 accaatgaaa aattggttaa aaatcatggt caagccagct gccaactgtt cgatgtccgt
     6661 ggttacacga ctaaccatct ctccactacc ttgcctatct acaaaggcaa tcggtaaacg
     6721 atggagctta tggatgattc gctctcgcaa gtctctggta taagagaaaa ttaggcgatt
     6781 atagaggaga ggattggccc attgtaccag agtatttcct attacaacca agagcatatg
     6841 gagaaaaatc tgccaaaaaa ctagtgatga accagccact aggacttggt caatgacctg
     6901 cccaatcaga ataggtaggt aaattgataa gccaacttgg gcaatagttc ctagaaaggc
     6961 taggaaaagg aggaaaggat ggcttgctaa atctacggct aaacgtttga gcgtctggtt
     7021 tacagtttgt cgtttcattc tagtcctcct tttcatgttg ggatgcattg atttcacgat
     7081 agacttggct ggatttcatc aagtcatcgt gcttgccaac agctagcaac tcaccttttt
     7141 ccaagaggag aatctggtcc gccatctgga gtgtcgaagt ccgttgagaa atcaagatta
     7201 agctcatatt tggcagattt tcgcggatag ctttcaagat cttggactcg gtaatggtgt
     7261 ccagtgccga ggtcgcatca tctaggatga gaaacggagc ctggcgcaag actgctcgtg
     7321 cgatagacag cctttgtttt tgtccacctg agaaatttcg cccccctgct tcaactagag
     7381 catccaagag tccttcctta tcactgacaa aatccttagc ttgagcaatt tccaaggctt
     7441 gccagagttc ttgatcagtc acttcttgat tgaaacctaa agtcaagttg gaacgaatag
     7501 ttcccttaaa gagttcgacc ttttgtggca cataggcaat ccaagatctc cattgctcca
     7561 aattaagagg actcagtcca tctagataaa ggtcaattct tcccttattt actggataaa
     7621 gtccaagtat gagttgaatc aagcttgatt taccagaacc agtcccccca atgataccaa
     7681 ggatttgtcc ttgaatcata tcaaaggaaa tgtctctcag agaaggctgg gccgcatcag
     7741 gataggtaaa ggtcaattct tggacttgta aaacccgatc actggtaact tgcttttgtt
     7801 ctaattctga atggatatcc tctggagcct caacaaagac ttcctcgatt cgcttggctg
     7861 agatatagga ctggttgagg gaatttatca acatggctag cttgaccaat tccaccaaaa
     7921 tctgtaagag gtaattgata agagcaatga gagcaccttg actgagcact cctccttgaa
     7981 ttgaaatata gccttgccag ataataacga gaagagttcc attgacaatc agataggtca
     8041 gaggtgttaa taaactagac cagaaacctg tcttttcttg taatctagca taaacttggt
     8101 taagggtttg aaaaatctgt aactctagtt tttcttgacc aaaagcacga ataacccgca
     8161 tcccttgcaa ttgctggcgc gtttcctgaa ccagttggtc cgttttcttt ctgagactac
     8221 tgtagagagg attgaccaat cgagataacc ctacaatgac aatggtcaaa atggcaacca
     8281 tgactaagaa ccagaaagtc aactcagctg agattcgata agccataaaa atggcaccaa
     8341 aaacgataat gggcgctcgt aaaaagagac gcaggaattg attgatacca gtctgaatct
     8401 ggtaggtatc cgaagtcaag cgagtgacca aactagaagt tgtcagacgg tctctgctgt
     8461 cctttggcaa ggaaagaata tgacgataaa gatcgtttgt caattcctta gcaaaaccta
     8521 ctgctgcctt tgctgagtaa aattgagcta tcaaggccac taaaacgcca attactgcaa
     8581 agataaggag cagaccaatc tgcatccaga gatgaccttg atctccctga ggtaaagatt
     8641 ggtcaacaat cccagcaatc accatgggaa ccaagagctc aaaaacagct tctaacagct
     8701 tgaacaaggg ggctaaaatt gattccttga tgtagggttt gaagtaagat aataggtgtt
     8761 tcataaatcc cttctattca tattctagaa atgaagaaag tgggaagccc cactctctgt
     8821 tttatttgtt taagtaaggc aatagatagc catatcctgc tttttccatc tcatccttgg
     8881 ccacaaagcg taaagaagca gaattgatac agtaacggag gccgcctaac tcccgcggtc
     8941 catctgtgaa aacatgaccc aagtgagcac tgcctgaacg agaacgaact tcaattcgct
     9001 ccattccatg gctcagatcc ttgtaataat gaatcaactc tttggaaatc ggacggctaa
     9061 aacttggcca accacaacct gaagcaaact tatccttggc aaaaaagagt ggctcacctg
     9121 tcgtaatatc tacataaatc ccctcttcaa aggtttggtc ataggcattg gtaaatggag
     9181 cctctgtagc agcttcttgt gtgacacgat aagactcttc agatagactg gccttcaaca
     9241 cctcttgact aggcttttca tagtttgctg catcaatcaa tggcttatca gcatcggtca
     9301 catcgatatg acagtaacct gaaggattct tcctgagata gtcttggtgg tagtcttcag
     9361 ccagaatgta gtggcgtaat tgctccactt ctactgcaat ctttcgaccc agcatgcgtt
     9421 cctgctcctg caccactgtg tagatagctg gcaaatctgc ttcatcctga taataaatcc
     9481 cagttcgata ttggcgacca cggtcattcc cttgttgatt gatagataga ggatcgataa
     9541 ctcggaaata ataaagtaaa atctctctga gtgacacttc cttctcatcg taaatcactt
     9601 ggaccgtttc tgcatggtct gtttccttga gcaactggta attggtcgtt tcgacttgac
     9661 cattagcgta gccaacactg gtttctagca ctccagaaat gcgtgaaaaa tattcctcta
     9721 ggccccaaaa acaaccacct gctagataaa tttctgccat ctttatttct cctttatcac
     9781 gtttttaact aatactcttc gaaaatctct tcaaaccacg ttagcgtcac cttaccgtat
     9841 atatgttact gacgtcgtca gttctatctg caacctcaaa acactgtctt gagctgactt
     9901 cgtcagttct atctgcaacc tcaaaacagt gtcttgagct gacttcgtca gttctatcca
     9961 caacctcaaa acactgtttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    10021 tcattgagta taaacttctt ttcacaaaaa ggatatgaaa ccctctggtc aagagtttcc
    10081 ccatcctatc ttctattctt tattttgctt ctacacggac accttgggta tcaactctca
    10141 agtcatgcag ttttcctttg aaaggttgct tttccaattc tgccttaatt gttggcatct
    10201 tgtcatgaga agccagaacc ataactgtcg gcccagcacc agaaaggtag gttgcatagg
    10261 ccccattttc tttggtcact tgcttaatca tcgcaaattc tcttaccaaa tcctgacgat
    10321 agcgctcatg gaagaggtct ccctcgattg cttgcccagc ggtcaccatg tctcctgcca
    10381 acaaggcagc aaccgctaca ttggcgatag aacttgcagc aacagcttcc ttataagaca
    10441 attttttagg caagacacta cggctgtcgc gagtacgtaa ttcatagttt ggaatgtaag
    10501 ctagaaaatc acactctgga aagtctgcta cgatagcaga gacttgccct tcaacagaac
    10561 ttgcaataac gagattacca taaatggctg gagccacatt gtcaggatgc ccttcaatct
    10621 tggtcgctaa ctgcaatttt tcatggtctg ataagttgag ttgacccagt tggttggcta
    10681 gttcaatccc agcaacgata accgagctgg aagaacccaa accgcgcgcc aaagggacat
    10741 cactggtcat tttcaagcgt cttggttgca agtctggtac aatttgcaaa gcgattttga
    10801 gcaagagatt acgctcatca tgtggaatcc atttgccaat ctggtgttca atcagccact
    10861 catctcgttc ttcgcagacc tcaatttgaa gatacttggt tacagctaca ccgaccgagt
    10921 caaaacctgg cccgatattg gcactggttg caggtacaat aatcttcatc ttattctcct
    10981 aacaccttga aggtattcaa gaggtcgaat tctgaaacct tcttcaattc agctgagaca
    11041 ttttcaagct gggctttatt aatcttgtgt gtgatgataa cgacacgcgc cttgtcaccc
    11101 tctttgccat cttgaaggat ttgcttaaag gaaatatctt gagcattgaa gatttcagcc
    11161 aacttcaaga cctgaccttt tgagtctaga gccaagattg agaaatagta gtttgctttg
    11221 acatcttcag gatttgccaa gaccaagtca cggctatatt cgttgaagtc tttgccaata
    11281 gtaccatcat tcaaacgacg aacgatacgg acaatatcag ctacaacact tgttgcagtt
    11341 ggtttttgac cagcacctgg tccgtagtac atagactcac caataccgat agattctaca
    11401 aagacagcgt tcattacgcc attcacacta gcaagtgggt gcgctttagg taggaaggtt
    11461 ggagtcactt ctgcagcaat acctgaagaa gtttcctcaa tagaaccaac caatttcact
    11521 acgtaaccaa gctcttgagc tacagctacg tcttctggtg tgatattgcg gattcccttg
    11581 tgggctacat catcaaaggc aatcttcatg ccaaaggcaa attggctcaa aataaccatc
    11641 ttgtaggctg catcaatccc atctacgtca ttcgtcggat cgctttctgc aaatcctaga
    11701 cgttgtgctt ccgcaagagc atcatcgtaa gaccagcctt cttccaccat cttggtcacc
    11761 atgaagttgg aagttccgtt gactactcca agcacgcgcg taattttatc agaagccaag
    11821 gaatttgcta aagtacgaag aattggaatc ccaccagcaa ctgctgcttc gtagtaaagt
    11881 gctaccttgt tagcttgagc gatttctagc aattctgcgc catggacagc taaaaggtcc
    11941 ttgttagcag taacaacgtg ttttccagct tccaaggcac gagtgataaa ggttttagca
    12001 ggctcaatac gccccatcaa ttccactacg atagtaatat cctggtctga taaaatatca
    12061 tccacattgg ttacaaagtt aaagtcattc cctgctgcaa gcaagcgatt tttttcatct
    12121 tcatccttga ccaatacctt agcaactttg atatctgaat gtgctgattg attgattttt
    12181 cctccatttt cctttaggag gaaaggcaca ccacttgcaa cggtaccaaa tcctagtaaa
    12241 gcaattttaa ctgtcatctt tatctcctcg aaattttcta atatagccat tataacagaa
    12301 ttttgtgaaa attcctatta tagtaaatca ctatttcagt ataaaaagaa aaaacgaatc
    12361 agacgattcg ctcttcttaa aatctgaaaa tagctttcca gaaaggatta gccgattttt
    12421 tgcagattga gcactgcatc gtgactcatc aagacttgac catactcttg taagactgag
    12481 cgactgatat cactatcgtc tgcaaactcg cgcatacggg ccaacagcca agctggatat
    12541 gggcttggat gattttcaat atccactaaa atggtcaaat aatagcgctc gttcattttg
    12601 tagagttcag aagtttccat ttcaaaagtc actgtcttgg caaaaactac caagtcagcc
    12661 aacttagcaa aagaaaggat gtagtagatg taaggttctt tcttactctc agcttcttgt
    12721 tcagcctgct cttgctcttc ttccttggct tcaacttgct caagagattg aatggcttcg
    12781 atatcatcct tggttttgtc tgcgatgctt ttttccaggg ttttgataaa ttcatctgga
    12841 gacatttgag ccaattcttc catatctggc aaatccgata agtcttcaaa atctagattt
    12901 tggtcaatct ttgacttggt cacaaagaca tctaccttat caggttttgg agtcacacgg
    12961 aagctcaaca tgcctgtatc cagaaagcta tcaggcatct ctagctcatc caagatagca
    13021 taaaagaact cttctgtttt ttcttgagga acgagaaagt cagcaatctc cattccacga
    13081 tccatcaaat cctctaaaga catcgtgatt tttaaagttg tatcactaat ttgtttcatt
    13141 ttcattgcta gtaacctcat actttcagtt ctatctatta tactagattt ttacgatttt
    13201 atcaaaagaa ggctcctcta tacggataga ttttccctag ggtctttcta taggagactc
    13261 caaaagaaaa tttctgcaga cagatagaaa aagccttcaa aatcagctct tagccgattt
    13321 tgaagacctt atacatcaga atacttataa tttaaaggtt gctacaccaa ggatagaacg
    13381 atttaagttt ctgagaattt gaagactttg ctcaaatttc ttataacgag tcactccgta
    13441 ctcttcaaca agaaggactg tatctctttc caaaagagat gatacatcct gtaaatctac
    13501 aaaatgcatt ccttttaaag cttcttgact ctgtttcaat ttatctagga tagctttatt
    13561 tgagctaacg atggtcaatt cctgtccagt atttttgtat gacaaaacat ctgctaggtt
    13621 agcaattgtt gtaatctctg ttacaaaatc aatttgatac tgagaaaaat cacctactct
    13681 attgattgtt ggattaaaga gataaactaa cacatttccc atcacaacca aaatcacaca
    13741 aaccactcca ataacaacta aacgaagaat cagatttttc acatttaagc caagcgctgt
    13801 ttcaccattt gcgttcaatt ctttagagtt gatggtttcc agtttttcaa ttttcacatt
    13861 tgcataggca tgtttaaatt tctcaatcaa cccatcaatt tttttctcta acaagtcatt
    13921 ggcatcttta cttgatgtca aaattttcac accaacccct gcatcgtcaa tcatatagta
    13981 gacggtcaat tttttccacc aatagtcatt cgttgaattt ttcaaggttg tttctgtcgt
    14041 gtctaattca ctggcaattt ttttcaactc actgggttct acatcattga aaagataagc
    14101 tccattcaaa ttaccatcaa tcaatttccc ataaaaatca ctataaccac caatttgatg
    14161 attcaaaatc gttttggccg actcttttgg aggagtgatt ttatagataa gataagttga
    14221 ataacttgtt gtatctttga cagtgttttt attcctaact gctttaattg taaatggtac
    14281 agcaatgaga gcaaataaag cgatgagagc taaaatattt gcttttcgct ttttataaag
    14341 atttgcaaac aaatcagcta ctgaataatg ttcaaacatg atttttttct cctttgttta
    14401 gtagatacta gttttccttt gtaaacattt ttgctacaaa tataatcaca agaacaattc
    14461 cccagaattg cattgtaaat aaattgaaga aactttctga aaagctgctt cttggcataa
    14521 agaatagatt attcaagatg agtagggata aagcaaatag gattatcctt gagcgatagg
    14581 ctacttgcag catggctata aataatacgc cgagtaagaa actaagcaga aagactccaa
    14641 tcataccata gtcggtatac aactccatga tataactact tccgatacca tgccctttca
    14701 agtattcctt gttcaagaca agataggata gattgtgggc ataactatta ctatcaatag
    14761 ctagttccac actattggtt gtatgttcaa aggcttttcc tccgaaaatg gctcccaaac
    14821 tcccccttgc aaaataatca agaacaggac caaaagtaaa attacggaaa tctcggtaag
    14881 ggaggctact gttaaataga aaacctcgag ccagaacacc aaaactagtc ccttgtttat
    14941 agataaagtc aagtaagata tcccagaaac ctgtatggga aacttggaca ttatcccgta
    15001 cataattgag tactcccatc gctaacatga gaataggaga acctacaaaa atcgctaact
    15061 tttctttaaa cccaatccat tttccttttt cagcttgctc ccgcataaag taataaacaa
    15121 aagcaaataa aatacttaaa ataaagggat ttcgtgtccc aattgccaaa tgaatagtgt
    15181 tagctgcaat aaaggagaca agcactgctg tggcctgcaa tttctttggc ttggttgcca
    15241 gatacataca cattgcatag accgtaaagg tagacaaaat gtaggtaaaa taaggcagtt
    15301 tactttcaaa atttgcatag taggcatagt aggaagtctg caaacgatac aagagccgtt
    15361 caaataaccg aatgaaatag aaaggataag ttagaagaaa aactcctagt gatacaaagc
    15421 gtaaccgctt gatataaacc tcttttagag aatttcctat atttgctact tttattttct
    15481 tcctagctat gaagtaacga gccaggacgc ctcctgttgt caagcccaga atcgaaacca
    15541 tgacaactat aaaggcaaaa cgataggcta ttggatgata ggtatccaaa gcaccatccc
    15601 taaaataatc aatggtcggt cttgatacca gaaatacaaa aatggttaaa tagaaaataa
    15661 aatggattaa gtaatacttg atatcattcc aacaagcaat caagctacta accaacaaga
    15721 acaataaagt agaaagtaag ctaacattat tattattaaa cagatacaca attccactta
    15781 ctagcgtcaa ggcataactg actatggtca aactaaataa taatcgtttc ccatcaatca
    15841 cttggtcacc cccgttctaa tgtaattttt tagatttttc aatatttttc agtaataaga
    15901 atcgatataa ggaaatattt atgaataggg ccaaagcact aattcttctc cccttacgga
    15961 aaattggatt cctagaaata gcaaaggcat ggtcttttaa aaaacgatga atctgagaat
    16021 aggctttaaa ctgtttatac tgatcatcta gcaacatctt atccagaata aagaagtggg
    16081 cataggccaa tctgaaaaaa gcgacctctt tcaagtcagg atagtttttc acaacttcat
    16141 tataaaactt ttggtagata tcaatatagg ctaaatcctt ctctgcatag ggtttggtcg
    16201 taatactatc ccctctatgg aaatagtaat aatagggttt agtattaacc acatacttct
    16261 tggccaactt gattaaatca aaatggtaat aggcatcttc gtaaatcaac cccttaggaa
    16321 aggatagggc agttgcaatc tgtctcttga ttagcttatt gcaaatcgtc ccaggtattt
    16381 tttcacctat gaggtattcc tttagaaatg tttgagaatc acagacaaaa tagtcatcct
    16441 gattggctga ctgtgggctt tcatcattag catagacatt catgacacca cagcttgaaa
    16501 catccgcatc ttcttgaact aattgctcat ataagctctg aatcatttct ggatggatat
    16561 aatcatctga gtcaataaaa atcagataat ccccgtgagc ctgcttcatc ccatcatttc
    16621 gtgcttgcga caatccttcg ttctttttat gaagcactga caccctgtca tcttgttcag
    16681 cgattgaatc acacaagcga ccactttcat ctgttgcacc atcatcaaca agaataattt
    16741 ccagattttg ataggtctgc ttctgaatgg aagctatcga tttttctagg tactgcgcca
    16801 cattatagac tggcacaatc acactaatta atgcagtttc catgctactc ctctaatagt
    16861 ttttctactt gttcgatttg ttttgtaatt gtaaattgtt gaatgaattg gctagcctca
    16921 tcgacatcaa agtttgaggc agaagtcatg taattagtaa tcgcctgagc tgcctcttga
    16981 ttgctctcaa tgatttgtcc aaatcgtcct tcttgggata attcctcagc ccctccaacg
    17041 ttcgtagaga taaaagggag tcccagactc aaggcctcca catacactcc aggaaaacct
    17101 tcttgtttag acatagacaa aagaactttc gtctgagata gatactgata aggatttttt
    17161 tgataaccaa ggaaatgtac atagtcctca atcccatact ctttgactcg ttttttcagt
    17221 tcctcttcca tatcaccagc cccgataaaa tagagatgat agttttttcc ctcttggtgt
    17281 aataatcgta tcacttccac tacacggtca gaacccttat tttcctcaat ccgtccgata
    17341 gtacagatac tttgaggagc aatctcgata tcgatcttct cttgagattt ttctagaata
    17401 gtctgaaaat catatccatt gtagattgtc tgtaatttag aagtataatc tggataaact
    17461 tccttgatag aattgctggt cttttttgaa atccctacaa ttgtattcgc agcatccaac
    17521 tggcttctat gtgattctct tttagagcta tccttaagaa gttcttcaat acttccatga
    17581 atccaagata tcttcttgac ttctcttctt ttagagaaca acagtggtgg attcataatg
    17641 gtaaaagaaa cttcaacatc ataatcatct tttacaagca aacgacgagc cagtcttgga
    17701 aaataaattc tcattctcca caaaaaagct cgtaaccatc tggtttggcg ataatcttga
    17761 agggatttta aaatgcgtac atgctttgga acagattcat atcccttgtc aaagtgctcc
    17821 atttcaagaa tatcaatatc atacttttct ggatccagat ttgaaacaat ggttgataga
    17881 atcttctctg caccacctcc aagagaaaaa gaccacataa aaaataagat ttttttctta
    17941 gccaccatat tctcccttgt attctgtata agacttatcc atatcagcga tgacagcatc
    18001 atgatgcggt acctgcttgt ctgctggtgg aggcgtcata taatccccaa aagcagttct
    18061 gagatagaca tcatagccga ttggaatagg catctctgtt ccttcaaatg gcaagaaaag
    18121 attgtcttca aaagatgtga ttgggtactt gtttctcatg tagccaggac ctgagcataa
    18181 ttctgtaatg ccatcacaat cagccaaatc atacttagtc atttctttct cagctttttt
    18241 ccagatgcga taacagagag attttggagt caaacccagt aaaatgcgac ttccccattt
    18301 catgagagca ccatgctttt ctggaatagt ttgcgcacaa aagagtgaat aaatcaaggc
    18361 ccaacgaacc tgttttttcc gctcagctgg atttttcgga taataatcca aaggcaaaac
    18421 atccaaggcc agaccatgtg gcaaatccaa atcctgctga taaggcttga tacaggtggt
    18481 ttccttgtca cgaatggtaa taaaaagatt acgatcaaca aaatccttgt gactctttga
    18541 caagaaataa cgttcatctg cataacgagg ccataattct gctaatttct cataatcttt
    18601 acgaggcata aaaaagtcta ggtcgtcgtc ccaaggaata aatcccttgt ttcgaagggc
    18661 accaatagcg cctccgccac agagataaca gagcaaatca tgttctttac aaaaggccac
    18721 aaaatattca gccatctcca gactacgagc ctgaattgct tttaaatcag tcatattgtt
    18781 cattattctt tctatcgtat cgtttcatta taccacaaac aaggggtgaa aatctattgc
    18841 agactgtaaa aaatcaaagc ctgactgcta tccaaatagc tatcaaactt tgatttttct
    18901 gtcttatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgcc gtaggtatag
    18961 gtaactgact tcgtcagtct tatctacaac ctcaaaactg tgtttttagc agcctgcggc
    19021 tagcttccta gtttgcactt tgattttcat tgagtattat cttatctcaa gcccatttga
    19081 gcgagcttgg tttgatattt gttttgatca accagcaagc ccaagcctcc ataaacatca
    19141 taggcatcta cccagtcacc cagttctgga atcctcaatt tttcaatacc attttttgct
    19201 ccatccaaaa cagataaacc gtttgttagg aggaaagtat agggtacgtt ggttgaggtc
    19261 atagcaaaaa cctttccaag agcttcagaa ccagtgaaaa gtttagtggg atctttaatt
    19321 tgctctaaaa ttgctgttaa aacttgttgc tgtctttttg tacggccgta atccgcctca
    19381 tcatcatcac ggaaacgagc ataattgagc agggtcgagc cattcatctg ctgttttccg
    19441 actttaatgg tttgggttgg agactcagtc tcggtagcgt ataaatcatc tccgactgta
    19501 gcttctgtta ggggacgccc attcaatgtt gaaaattgag catcaatcgt caccccatca
    19561 gggaaaagcg tgtcaatcgc tgtggcaaag gcctggaaat caaccaaggc gtagtactta
    19621 atgtccaagt caaaattatc tttcaagact tggcgaacca tttctgcccc tttttgcccc
    19681 tcttgttctc ctaactcgta ggctacgttt aacttgttat ctgtctgttt tctaccgtta
    19741 atcacttgac tataaccatc tatatagacc aaattatcac gcatgaaact gactagcttc
    19801 attttcttat ctgagccccc gacatttaat accataatag agtcagttcg tgtctcaaca
    19861 ctgttctggc cgattcgacc atcagtaccc atgattaaaa tattaactcc atctctagtg
    19921 tcctgaccat taaagacttc tacttgagct gcccgggcat cagcagtttt ctttgcgcta
    19981 gcatcttggt aaccacgcaa aaacatgaat accatggcca aagccacaca gaccaaaagt
    20041 gaaaaaatca ccataaaaat tcgtttaaga cggagcttcc gtcttttctt ttttggaggg
    20101 gaagagagtg cttgtgattt ggattgtgag cgactccggt tcgcatagct tggtaagtca
    20161 acctgctctt ctctttcttg ttccaagcta gagctactat ttcccctagc aagagttagc
    20221 ttttcttgca aataggcaaa ctcatttttt tctctctcat tgagatagtg aatatttttt
    20281 agcaaataat cataacgcaa ctgctcatga tgacttaagg gattttcttt actcatcttc
    20341 tctcctttcc atggtctgat attggataaa taggataggc acccagaatt ttatactgga
    20401 ttccaatcgc ttctaattct ttttgggcaa agtggaccaa gtccttatcg gtataatcca
    20461 catcgataat gaaaaagtat tcacccagtg ctgtcttgag tggacgactt tcaatttttg
    20521 tcaagtcaat tcctcgccaa gcaaaggtcg acagggcctt ataaagtgca cctggaaggt
    20581 tgtcaggtaa tgtcaaggcc aaactcatct tttcagtttg tgcttgcaag ggaatactag
    20641 gcttttcagc tcctagaacc cagaaacgtg tgaaattggc ttccatttcc tgaatatcct
    20701 cggcaatcag ttccaatcca tattcttcag cagaacttct aggtgcaact gctgcaaagg
    20761 gctggtctgg atgttcggaa ataaaacggg ccgcataagc tgtactagct gttacctcga
    20821 tttgagcctc tggatattgt tcatcgatga atttctttcc ttgagccaag gcctgtggat
    20881 gtgaaaaaat cttttcaatc ttagtatggc ctggaaccac catcaactgc tgatgaatag
    20941 gctgaacgat ttctgctact gcttggatgt gagcctgatg aaaaagatag tccaaggttt
    21001 catgaacact accctcaata gaattttcaa ctggcaccac agaatagtcc actaatcctt
    21061 gctcataagc cttgatgaca tctgtaatgt tggcaaaagc ctgcaattcc tcatgaggaa
    21121 aagctgtctg cacaacgtgg tgtgaaaatg atcctttggg acctagataa gcaattttca
    21181 tcttagttcc tctataattt cctctgggct tagcttggtc acatccaaaa cccgactagc
    21241 cacttcctca taccaagcct gtctttcttg aaaaatagct actagttctt ccttgctatt
    21301 atttagaaaa agcggtcgct gattgtcctt atcagctgcg atacgttggt agagggtttc
    21361 aaaatctgct ttcaggtaga tgttatctgt attagtcttg agtaagtcac gatttctctg
    21421 agaaataacc actcctcctc cagttgacac gacttggtct gtttgtagta aatcagctag
    21481 gacttctgat tctacctgac gaaaggctgc ttctcccttt tcagcgaaaa aattcgcaat
    21541 ggacatacct aggcgcttct caatcagagc atccatatca aggtaattag ggtccaagcc
    21601 tcttgcaata gtcgattttc cagcccccat aaaccctaat aacaccttag ccatgaatca
    21661 agctctccaa atcatcaaag aaactaggat agctggtatt gatggcttct gcacggtcaa
    21721 gctccacctc tccatctgca accaagaggg ctgcgatagc tgtcatcatg ccgatacggt
    21781 ggtcaccaaa cgtattgact ctagcaccgt gaagagctga tttccctttg ataatcatcc
    21841 catctgccgt aggagtaata tctgctccca tactatttaa ggcgtctgcc acaacctgaa
    21901 tacggtctgt ttccttgacc ttgagctcct cagcatcctt gataactgtt acaccttggg
    21961 cttgagtcgc aagcagggca ataatgggca attcatcaat caatcgtgga atcaaagcgc
    22021 caccaatctc tgttcctttc aagtcagaag actcaacagt caaggtagaa gatttagcga
    22081 ctggatcgat ttcagttatt tccaattttc cacccatggc acgaatgaca tcaataatac
    22141 cggtgcgagt ttcgttgatc cccacattct gcagcactag acgagaattt ggaacaatca
    22201 aacctgcgac taaccaaaag gctgcactgg aaatatctcc tggtacgacc accttctgtc
    22261 ctgtcaattt ttgtggccct tggactgtga ttttcttacc atccacactt aaatgaccac
    22321 caaattgttt caacatatct tcagtatgat tacgggtgca ctctttttcg ataataactg
    22381 actccccctt agcttgtaag gctgcaaaca tcaaggctga cttgacttgg gcagaggcaa
    22441 ttggcaactc ataatgaata ggtcttaggt ttttcgtccc ttttaagcga aggggaggca
    22501 agtctcgttc agtttgccct gaaatgctga cgcccatttt tttcagtgga agggtcacac
    22561 ggtccatagg acgtttggaa agactatcat ctccaaacat ctctacttcg aaatctgcac
    22621 cagcaaggac acctgaaatc aggcgaatcg aggtgccaga atttcccata ttaagggcat
    22681 tttgtggcgc ttttaagcca gccatgccta caccttgaat ggtaataacc ccatctttat
    22741 cctcaatttc aacaccaagg tcacgaaaaa cctgcatggt cgaaagaacg tcttcacctc
    22801 gcagaatatc ataaaccttg gtctcaccct cagccaaact tccaaagata atggaacggt
    22861 ggctgataga cttgtcacct gggacgcgga tactaccatg taaatggcga atgtttgttt
    22921 ttagtttcat actggacctc atacttgcaa tacttttacc tattttatca taaaaagcca
    22981 gaaattcctt aaaaattcct gactttagga tcgttctttt cttatttcag caattctgaa
    23041 actggttcaa aaacaatttt ttcaatgtca gaaaggtaaa tggccaattg ttgttgcttg
    23101 gtaaagaatt ctgacaagag gctatttcct tgaatctgtt taccaaagcc ttccatctta
    23161 gcttggaagg acgcatctgg catttgacct gtctgtgcta gtttttgaat ttcctcttga
    23221 aaggcaagat attctgtaaa gattttgctt gcctcagcat ctgctgcaat cgcatcttta
    23281 gctgctttaa cagccttgta ttctggtaat ccgcgtagac cgcgactgag ttcgtttgca
    23341 ctatcgtaaa tatttgacat gttcttctcc ttatttgatg acgactgtat agtcggtatt
    23401 ttctgttatg agatgctcag ctctttccaa gtctcgagca tttttaaatg aaatttgtag
    23461 gattccgtga atatcctcac gattttcctc gttgatgtgg atgttaacca aggaagttcc
    23521 acgtagcagt tccaaaatcc gcaggatgac atcttcttca tcaggaacgt caacatagag
    23581 gtcgtaagag ctatccacac caccacgctt atggatttcc atggtctggc gttgttcacg
    23641 cgcttggtta aaaaagttcc aaatttgctc ttcatctccc ttactaatgg cctgaccaat
    23701 cacttccaaa cgttccttga aatcctcaat tctatccaga atggtctcgc tattggacaa
    23761 gagaatggag gtccacattc ctggctcgct ttccgcaatt cgggtcatat ctcgaaaacc
    23821 acctgccgca aagcgccttg ccatctcatg ctcttgagca tagaccgcag tctgctccat
    23881 gagactagaa gccaaaatat gaggaaaatg gctaatctga gaagtgacac gatcatgctc
    23941 cttggcatca atctcgataa aacgagcatg aagacctgaa agcagatcct tcatttcctt
    24001 aagcgtgtcc tgacttgtca ggcttgaagg tgtaaagata taataggcat tttcaaaaag
    24061 attgacatct gccgaagcag cccctgtctt gtgactacca gccatgggat gggccccgac
    24121 aaagcgaaca gacttgccag ccaaatactg ctccgccgca tccacaatgg ttgacttggt
    24181 cgaaccagca tctgaaataa taacgccttc tcgcaaatcc aaattggcca actccttaat
    24241 gaaagcaata gtttgtttga ttggcaagct gaggataatg acatctgcca aaggagcaaa
    24301 actagcaaaa tcatccgttg cacggtcaat catgccttct ttcaaggcga tatctctcga
    24361 agcttgacta cgattataac ctaaaatttc ataatctgga tgatcgcgtt tgataccaag
    24421 tgccatagag gctccaatca acccaagacc tgcgatatag attgtttttg ccataggaac
    24481 tccttaatag ttctttgtat agtctcggtg tttggctacc gcttctttta gttcctcaag
    24541 attatctgat gagaattttt cgaggatttc ttgcgccaga accgttgcta caactgcttc
    24601 catgaccatt cctgcagctg gaagagcagt cggatcactt ctctccacgg ttgccttgta
    24661 aggttcgtgg gtttcgatat ccacactcat aagaggttta taaagagtag gaatgggttt
    24721 catgacccca cgaacaacga tgggttgccc attagtcata ccaccttcaa aaccacctag
    24781 attattggta cggcgagtat aaccgtcttc tttagaccag agaatttcat ccataacttg
    24841 gctgccttta cgataaccag cctcaaagcc aagaccaaat tccacccctt taaaggcatt
    24901 gatagagaca acagcttgag ccaatcttgc atccaatttt ctatcccatt ggacatagga
    24961 accaagacca actggaacgc ctccgacgac tgtctccaca accccaccga tggtatcacc
    25021 atcacgtttg atttggtcaa tatagtcctt gatttcctgt tctcgttctt ggttgacaat
    25081 agaaacttca gactgggcag ctctttgctt aatttcagcg actgtcagat tttcaggaac
    25141 atcgatttcc ttgccaccaa agaccacgac atggttggca atctccacat ccagctcaac
    25201 caagaggcgt ttggctactg caccaactgc cacccgcatg gtggtttcac gagctgatga
    25261 acgctccaaa gaatttcgca aatcatcaaa acggtactta atccccccaa ccaaatcggc
    25321 atgacctggg cgaggatgag taattttccg cttgctttta aggcggtctt caatgtcctc
    25381 cgcagacatg atgtccagcc atttctggtg gtccttattg atgacatcca tagtaatagg
    25441 cgcccctgtc gtcttcccgt ggcgaacgcc cgaagtaaag acaacctggt cattctcaat
    25501 cttcatacga ccaccacgac cgtagccacc ctgacggcgt ctaaggtcct cattgatatc
    25561 ctcagctgtc aatggaagtc cagctggaat tccctcaata atagctgtta gacgggggcc
    25621 gtgtgattct cctgcagtta aatatctcat acactctcct tattttacca agtagtcttt
    25681 catctcttcc agagaaactg gatgaatggt cgctgaacca agctctggca ccaagaccaa
    25741 tttcaaggtg ttgccacgcg ctttcttgtc atgagtaaga gcctgataaa gcttgtcaac
    25801 ttcccaattt tcatagtcaa caggcaagcc gaatttctga cacatctctg tgatagattg
    25861 ggtaatgcca gctggcatga ggcctttttc ctcagcaatc ttggaaatct gtaccattcc
    25921 catggcaaca gcctctccat gcatgacctt gccataaccg gcagtcgctt cgatggcatg
    25981 gccaatagtg tggccaaaat tgaggtaaag acgaatacca ttgtccaact catcttcaac
    26041 caccatcttg cgcttcacct gacaagaatg ttcaatcaag gtctctgcat gttccaaaat
    26101 gctctcaaca gaaccattca gtcccgtcaa gagagcccac agttctggat cctcaatcaa
    26161 gccatacttg ataacttcac ccatcccttc aatcaactct ctttttccga gggtttcaag
    26221 aacaagtgga tcaatcagaa ccccatctgg ttgggcaaag gtccccacca tatttttagc
    26281 aaatggtgtg ttaacgcctg tctttccacc gatagaagaa tcaacctgag ctgtcaaact
    26341 agtcggaatc tgaacaaagt gaataccccg catataggta gaggctacaa agccagccag
    26401 gtccccaaca acgccaccac caagagcaac gattccatcg ctacgagtca gaccttgctt
    26461 gactagaaat tcatagactt tctgaacagt agttaaattc tttctttctt caccttctaa
    26521 gaaatcaaaa acagctacct gaaaaccagc atcttctagg ctgagcttga ccttctctgc
    26581 atagagagag gctacatggt tatctgtcac aatgactacc ttttgcggtt gccagagttc
    26641 tcgcaaccac tgaccagcct gggccataca acctttttca atctgaatat cataaggatg
    26701 atgaggaata tcgattctga ttttcatagg agagtctccc tttctttatt ggtatttttc
    26761 tgttaaagac tgccaaatct cttctgtcgg catttccttg cctatccaca gttgaaaagc
    26821 ttctgcagct tgatagagca acattcccag accattgact gctggattgc cctgacttct
    26881 agcccatttc aaaaacggtg tttcaaaggg ttggtatatg atatctgcaa ctaaaagagt
    26941 ttctggtaag actatgtttt caggaacagg agaggattgg ccatccatgc ccacactggt
    27001 ggcattaact agcaaatccg actcggcaat ccttgcttgc agttcagaaa catattctaa
    27061 agcacacaaa tccactttaa agcctgtctg ctcctgtaac ttgtctaggt aaggtcttgt
    27121 tttttccata gaaacggaac gaacaaagac cgaaatctga ctgacgccat ccaaaatagc
    27181 ctgtgccaag attgatttag ccgcaccacc tgcacccagc agggtcatct ttttacctga
    27241 aattgtaaaa gaaggcaagc acttaaaaaa tcccttgcca tctgtattat atccaattaa
    27301 attgccattc tcattgacaa ccgtattaac cgcaccaatc aagcgcgctt catcgcttag
    27361 ctcatccaaa taaggaatca cctgctcctt atagggcatg gacagattga tgccaaacat
    27421 ctggtagcga cgaatattgg ccactgtttc tgccaagtca ctcgcttcaa tctcccaagc
    27481 cacataagca ccgttggtag ctgtcgcctc aaaggctcta ttgtggatga agggagaaat
    27541 agaatgctta ataggattgg caacaactgc agctaaacgt gtatagccat caagcttcat
    27601 ccaaaatctc cctgattttt ttcatgctag ctagagaaat ctgcccaggg gcactaacct
    27661 catccagact ggcaaaagac caactcgaac cagtcacatc cgcagtgata cgagagacct
    27721 tgcccacctt acccatagaa atggtcacat attcctgttc aggattgagg gttttaaagc
    27781 ctcgtgtata gttcatcaag tctaagacat cctgctccgt gtgagccatc accgcaacct
    27841 taacaagttt tggatttagg atcgtcaact ctgacaagat ttccatcatg ttctcaggtg
    27901 tttcttggaa attatggtaa ctcaaaacaa gatttgggaa gtccagcatt tcctcaaaaa
    27961 catccttgta gctatagtac tcaaaatcaa tatagtctgg ttgatagagt tgcgcaactt
    28021 ccttgattag atggatatac tcttctggag aaaggtcgat ttctccacct tcggagcgag
    28081 ttcgtagcgt gaaaaccaac tcacggcctg cgaatttttc aaaaatggct ggagctacct
    28141 gcaaaatcgc ttctttaggc agatagtcgg cacgccattc aatgatgtcg gcatccaggt
    28201 acctcgtggc atccagagcc tgagcctcct ctaaacttct tggcattact gaaacgatta
    28261 atttcattta ctaaccttca tactaatcac cttgaggtaa ttactacttt catctttttt
    28321 attataggca aaatctgctg gaagaccata tttgtttaaa atctggtaac ttcttcctgc
    28381 aaaaccttta tcaatttgtt ctgtaaattt ctgacgggaa acattggcag cattggtact
    28441 ggcaatgata atccctcccg gatttaaaat ctcaagactc tgggaaatca acttgtgata
    28501 atccttggcc acagagaaag tttgtttttt attccgagca aagctaggcg gatctaggac
    28561 aatcacatcg taggtcaagt ctttgcgttt ggcatatttg aaatactcaa agacatccat
    28621 gactataaaa cgatgctcgt ctgtgctgag cccatttgcc tgaaaatgcg cttgagacaa
    28681 ttctcgtgaa cgtttggcta gatcaacaga agttgtatgg ctagctcctc ccatggccgc
    28741 agctactgaa aaagccgctg tgtaggaaaa catattgagt aaggatttac ccatagccaa
    28801 gccgtcaact aaactaccgc gaacctcatg ctggtctagg aaaattcctg tcatcaagcc
    28861 atcattcata aagacttgat acaggacacc attttctaaa acagtgaaaa agtcaggtgc
    28921 ttcttgacca taaacatggg cagattcata gttcaaaccc ttaaagcgga ttttctcata
    28981 agctcctaaa acttcaggga aaacctgtct aaaggcttct gatatagtct gacgaatctg
    29041 ataaacataa gagttatacc aagaaaagac ggcgtagtcg ccataaaggt ccactgtcag
    29101 acccccaaag ccatctccct cttgattaaa gagacgaaag gcagttgtca aatcatcttg
    29161 atagtaggcg tttctctttt ctttggcttt tctaaacaac gtttcaaaga aagcttgatt
    29221 gaaggccacc ttgtctttgc tgataaacca gcccaagccc ttgttttgct gagaaaggta
    29281 ggcagtccca agaaagtttc cttcctgacc ctgcacctct acttcccgat ccttaagatt
    29341 gacattctca agatcactgg cttctagtaa aactagcccc ttagcaagct tcttttcaac
    29401 ccttttgctg actcttattc tattcataac taccattata tcaaactttt agacaattct
    29461 caaaaaagaa actacccttg cttttttact cttcttttaa aaaatggtat actagacttc
    29521 ctgcaaaact aggaaataaa tgtgtaagaa tcacaataaa aaatgctctt ccgtcttgga
    29581 ggagcatttc tttttatcaa cgaaaatcaa atagcaaact atgaaactag cctcaggtta
    29641 accgtgagat tataggtaga gaggttgtat cagcaatatg tgtctgtcaa atttagtgac
    29701 aaaggtagta gaagaaagat gaagaaataa atcagcttca gtaggtatct ggaaaatttg
    29761 attttataga gaagcctttt gttacaaact caatatacta tcaataaata atattataga
    29821 agcaacaata attaaaattt cacctatttg catcattcta tttcgaactc taaatatatg
    29881 ttctatcaaa aatacttgga tcacacacat tataggaatt aacgtttttg aaattgaaaa
    29941 atatcccaat aaataaacta taaacaacaa taatagaact atattatatt tcttattcaa
    30001 aacattcctc cctatatttt tgattaccaa tcttaatcat ttacaactac attctaacaa
    30061 actataaaag cgtttgtcga attgaattta tcaagcaagc aaccaactat ctcatctttt
    30121 ttctatttct gccaatatgc gtgacaggta ataatgatag ccaaaaatag caagagcaag
    30181 caagacgata agagctccta ctcccaagtt gatggcaagg ataggggaga gagactgaac
    30241 caagaatatg ctcccaatta caagggccat caggattgca ctataaataa acaataaaac
    30301 tatggcgact atgccatttg aacgcttcac caggtccgta atgctactcc aattggttga
    30361 cagattttta acgtccttaa agtaatggtg gcaagaaagg atgacactgg caatgatcca
    30421 gactacaaga aggtaaatca tcgaaaggat ggacaagcct agatatagag aaagaccgag
    30481 caaagtcaga attggtaaaa aggactgaac agcatagata atccaaaatt tcactttcac
    30541 ataacgagca aagtcaaagg gtaaactctt cagaaaatca agattttccc tctccaagga
    30601 caaggcaatt gaatgcaggc tggtgatatt gttattgaca actgctataa acactcctac
    30661 aaaaaacaag ggtaaccagt atggaggatg aatgtctgga actatctgag aatctcggat
    30721 tttggaaatc agactgatca tcatgagata aggaaggaaa gcacttgtaa aaagcactgt
    30781 aatcacgcca gtcccctgtc ccaagagggt gaggtggtag cgtaaaacca tacggaaaaa
    30841 gcccttttta gtagttgaaa tcctctcctt gctgcgacgt tcttttttga ccttctcctc
    30901 actgttaagc aggatcacgt cataaaaacg aggaaggacc ttctttttgg tcaggtaaag
    30961 caagaaaaca gttaaagcta tccaagcgag cagacccaat atggcttcta ttgaaaaagg
    31021 ctccactgct attttgtaaa agatatgaag aggataaagg agaaatggaa tgtctctaac
    31081 tttgtcaaca atacttccaa aagtcgactg tagaaagaag acaaatatta aaggtatgag
    31141 aactcctatc ccaatcatca cattcgaaaa aatagactga tactttctga agaccgtagt
    31201 ttgagccaag aaatgcactg ccactaccat cactagagcc acagagacaa ataataaggt
    31261 caaggacagt agcatcaaag gcaaacccag ccatagagaa ggagctagcc taatgtagag
    31321 gactagaaaa taagctagga ttggtacaat tccagttaga gctggcaaaa ggacagacag
    31381 tcctttagca attataatct ctgattcttt aaaggcatag ggcctatagg aggccaggtc
    31441 cttactctca taaaagacat tgtaaaaggc cgttaaagaa gttgaaaagg caatcactag
    31501 taaaatagca accatcgagc taaaataaat aggcatttcc tcaaaaggaa aatgaatggc
    31561 tatattacta aaacagatga gcatcaagag actggaaaaa atgtaagaac ttaggactct
    31621 agcagaaaca tttacttttt tcccaggatt cttagcctgc ttctttcgta gattagccag
    31681 attagcttct tgagatgaat agaggatatt gatatcaact aattttttaa tgaccttgag
    31741 acgcatccgc aacctcctct tttctaccag caagactaag gtagatactt tccaaaaact
    31801 ggtctgggtg gtctttcctc aagttctcta cactaccaca atagatcaaa tgcccctttt
    31861 tcaaaatagc aatccgatca cagacttgct cggctacctc aaggacatga gttgaaaaca
    31921 agaccgtctt gcctttttgt gcatgttcct tcatcatttg cttcaaatca aaggcggcct
    31981 ggggatccaa accagtcaag ggttcgtcca aaacccaaat atcaggagca gacaagagtg
    32041 ccccaatgac aaagactttc tgacgcattc cgtgagaaag agtttcaata acctgatagc
    32101 ggttttcagc aaaatcaaaa acgttcaata gcctagctag actagtctcc aagtcagagc
    32161 tagtcagatc ataggatgaa gcgatcaatt cccaaaattc attggccgtt aagcgtaaaa
    32221 ataagtcagg cgagtctgct acgtagccaa tctttcgttt gatcgccaag cgattttccg
    32281 ataactcctg accgtctacc aaaatacgac cactgctggg tgaaatgata ctgactaggg
    32341 attttatggt ggtcgatttt ccagccccat tatgaccaat caagcccata atctctccat
    32401 tttcaatctg caaattgaga ttactcaagg cctctttatc accatacaac ttactaacat
    32461 tttgaaattc aatcatggga caactcctat ctttatctgt attatacatc gctatactag
    32521 cactttgata caaaaaaatc aatactttat tttaagtagt taaaatagtt tccttctatc
    32581 ttacgcaaac gtttgcgccg agagatactt tatgatagaa taaagaacaa gattgacaag
    32641 taagaggaaa catcatgcaa aatcaaacac tcatgcaata ctttgaatgg tatctgcccc
    32701 acgacggtca acactggacg cgtctggctg aaaatgctcc acacctagct catctgggga
    32761 tcagtcacgt ctggatgcca ccagccttca aggcaaccaa cgaaaaagat gtcggctatg
    32821 gggtctatga cttatttgac ttaggagagt tcaaccaaaa agggactgtc cgcaccaagt
    32881 atggtttcaa agaagactat cttcaagcca ttcaagccct taaagaacag ggaattcaac
    32941 ctatggccga tgtagttctc aaccacaagg ctgctgccga taacagggaa gcctttcagg
    33001 ttatcgaagt tgatcctgta gaccgtacag ttgaacttgg agaacccttc accatcaatg
    33061 gctggactag ttttaccttc gatggtcgcc aagataccta taatggcttc cactggcatt
    33121 ggtaccactt caccggtaca gactacgatg ccaaacgcag taaatctggg atttatctga
    33181 tccaagggga caacaagggc tgggctaaca aggaattggt cgataacgaa aacggaaact
    33241 acgactacct catgtatgcc gacctagact ttaaacatcc tgaagtcatc caaaacatct
    33301 atgactgggc tgattggttc atggaaacga ctggtgtagc tggtttccgt ttggatgccg
    33361 ttaagcatat tgactctttc tttatgcgca acttcatccg cgatatgaag gaaaaatacg
    33421 gtgacgattt ctatgttttt ggtgaatttt ggaacccaga caaggaagcc aatctggact
    33481 atctcgaaaa aacggaagaa cactttgacc ttgtcgatgt tcgtctccac cagaatctct
    33541 ttgaagccag tcaagctggc gcaaactatg accttcgtgg cattttcaca gatagcctgg
    33601 ttgaactcaa gcctgacaag gctgtgactt ttgtcgacaa ccacgatacc caacgaggac
    33661 aagcccttga gtctaccgtt gaagaatggt tcaagccagc agcctatgcc ctcattttgt
    33721 tacgccaaga cggccttcca tgtgtctttt acggagacta ctatgggatt tcaggccagt
    33781 atgctcaaga agatttcaaa gaaatccttg accgcctcct agccatccga aaagacttgg
    33841 cctatggaga acaaaatgac tactttgacc atgctaactg tatcggttgg gtacgttcag
    33901 gtgctgaaaa tcaatcccca atcgcagtcc ttatctcaaa tgaccaagaa aacagcaagt
    33961 caatgtttgt cggtcaagaa tggactaatc aaacctttgt agatttactt ggtaaccacc
    34021 aaggtcaagt tacaattgat gaggaaggtt atggacaatt ccctgtctca gctagatccg
    34081 taagtgtctg ggcagtcaat accatctaat agctcataat aaccaagcta ggtccaagcg
    34141 gatttggctt ttttgtattc acaaaaagac ctacccaaat ggatagatct ttacttgatt
    34201 acaatttacc tgctactgca tccaacaatt cttggatctt agcttggttg cttcctcctg
    34261 ccatggccat gtctggttta ccaccaccac gtccatcgat gattggtgct aattctttga
    34321 caaggtttcc tgcatgaagg tcttttgtct tgcttgctac aaggacattg actttgtcac
    34381 cgatagcggc aactaggaca agaagatcag agtagtcttt ttgtttccag ttatctgcaa
    34441 aagtacgaag ggcaccggca tcggatacag acacttgact agcaatgtaa cgatgaccgt
    34501 tgacttcctt aacatctttg aagatatcgc ctgcggctgc agctgcggct ttttctttca
    34561 actcagcatt ttctttttga agttgacgaa gttgttcttg aagtccttct accttgtgag
    34621 gtacttcctt gacttgaggt gctttcaagg ttgctgcgat agctttaaga gcatcctctt
    34681 gttcacgata ggcttcaaag gcttccttac cagtcactgc caagatacgg cgagttcctg
    34741 aaccgattcc ttcttctttg acaattttga agagaccaat ctcagaagtg ttgtcaacat
    34801 gagtaccacc acaaagttca atagagtagt caccgatagt cacgacacga acttccttgc
    34861 cgtatttctc accaaagagg gccatagctc ccatttcttt agcagtgtca atatccgttt
    34921 caactgtctt cacttcaagt gcttcccaaa ttttctcgtt aacttgctgt tcaatcgcac
    34981 gaagttcctc agcagttact gcttggaagt gggtaaagtc aaagcgaagg aattcaactt
    35041 cgttaagaga tcctgcctgt gttgcgtggt ttccaaggat attgtgaagg gcagcgtgaa
    35101 gcaaatgagt cgcagtgtgg tttttcatga cacggtgacg gcgattgcta tcaattgcca
    35161 aggtatattc ttggttcaag gcaagcggtg caaggacttc aactgtatga agggcttgac
    35221 catttggggc tttctgaaca ttggtcacag tagccacaat cttacctgac tcatccaaga
    35281 tttgtccgta gtcagctacc tgtccaccca tttcagcata aaatgacgtt tccgcaaaga
    35341 taagagaggc agttccttct gaaacagctc ctacttctgc attgtcagca acgatagcta
    35401 ccaatttaga agacaattgg ctagtattgt agttgaagac actttctaca gtgatgtttt
    35461 gaagagtttc attttgcata cccattgagc cacccttgac agctgacgca cgcgcgcgtt
    35521 cttgctgttc tttcatggct gcttcaaaac cttcacggtc tacagtcata ccagcttctt
    35581 cagcgatttc ttcagtcaat tcaactggga acccataagt atcatagagt ttaaagacat
    35641 cttgaccagc aatgacagat tgaccttttt ctttcaagtc tgccacaatg ccttgggcaa
    35701 agtgttgacc tgagtgaagg gtacgggcaa atgattcttc ttcgctctta acgattttct
    35761 caataaagtc acgtttctca agcacttctg ggtagtagct ttccatgatt tttccaacag
    35821 ttggaaccaa tttgtaaagg aaaggctcgt tgatacccaa tttttgacca tgcatagaag
    35881 cacgacggag aagacgacga agaacataac cacgaccttc atttcctgga agggcaccat
    35941 caccgatagc aaatgaaaga gaacgaatgt ggtctgcgat aaccttgaag ctcatgttgt
    36001 cgccatcttg gtcataaacc ttaccagaca atttctcgac ttcacggata atcggcatga
    36061 agaggtccgt ttcaaagttg gtcttagccc cttggataac ggccaccaaa cgctccaaac
    36121 cagcgcccgt atcaatgttc ttatgtggca attccttgta ttcgctacga ggaacagcag
    36181 ggtctgcgtt aaattgtgac aaaacgatgt tccagatttc aatataacgg tcgttttcaa
    36241 tatcttctgc aagcaggcga agaccgatat tttctgggtc aaaggcttcc ccacggtcaa
    36301 agaagatttc tgtatctggt ccagaaggtc ccgcaccgat ttcccagaag ttgtcctcaa
    36361 ttggaatcaa gtgacttgga tccactccca cttcaatcca gcggttgtaa gaatctttat
    36421 cgtctggata gtaggtcatg taaagttttt cagcagggaa atcaaaccat tcagggcttg
    36481 tcaaaagctc ataagcccaa gtgatagctt cgtcacggaa gtaatccccg atagagaagt
    36541 tccccagcat ttcaaacatg gtatggtgac gcgcagtctt ccctacgttt tcgatgtcgt
    36601 tggtacggat agccttttgg gcattggtaa tacgtggatt ttcagggata atggtcccgt
    36661 caaagtattt cttaagggtt gctaccccag agttgatcca caaaagagtt gggtcattta
    36721 caggaaccaa acttactgat ggttctactg agtgaccttt ggtcgcccag aaatcaagcc
    36781 acatttggcg tacttgtgca ctagatagtt gtttcatatt gtctccttat tcacttgttt
    36841 aatgtgattg gctttccagc atttccacat agtcaatcgc gacacagagg gaaatgacta
    36901 ggtctgcata agcgtcttca agaaccgtta cggtataggt agaggtcaga tggaagagtt
    36961 ccttcttaat ttccgcaatc aactgatcgc gatcatccag caatttgaaa ttcaaatccc
    37021 agatattgcc ctcgatacga agacctagat tatcaaactc atacttatct cgccagaagg
    37081 tcaacttctt acgaatgaca aaactcgagc catcccgaag ctgaatctca aaacgaggaa
    37141 gcaaggtcaa gatttcttta ctgatctgac tgacttgttc accagccgca tcatagatgg
    37201 taaaagtttt gggaatctta aaaaatgatc cctccacctg ataggcaatt tctcccctgt
    37261 catccttgat agcgaagcgt tcgcctccaa gacgaaactt ttgtttgaca agaaatgttt
    37321 tcatcaacac ctccaaaaat caaaagacaa gctcatatca cgaagggcga aaaaccgcgg
    37381 taccaccttc attcaatgaa cttgtcattc tcttgttctt atgcaattgt atgattgagt
    37441 agcatgactt cctagcttag atggctcgca gcaccgccat ttctctggac taagacaagt
    37501 gaaaatcaat tctcaacttt cttattataa cgttttttta agcttgcgtc aactggaaat
    37561 gatctccgtt gaattagacc aattccctac atctctgatt actttttcag gatatatttt
    37621 ttcttactgc catttttctt tttatcccaa attttcatat tactaaacac agctactaga
    37681 atatttccaa atataaaggt gcctatcacc caatatatgg actcagttgt taggtattgt
    37741 cgatccaagc catcctttaa atggaatagt atagcagttt ggttaacaat cataaaggtt
    37801 ggccagaaac tttttttgaa aaaagtagac attttcatta tttgttgccg ctttctgtaa
    37861 ggttaatact caataaaaat caaaaagcaa actaggaagc tagcttcaag ctgtacttga
    37921 gtacggcaag gcaacgctga cgtggtttga agagtatagg cttagtatac tactaggcaa
    37981 gcaaataagc aaataaacaa ataaacaact agaatagaaa aagatagggc tctaaaaact
    38041 gacttctatt ccttaaaaac gaaccagctt gactgattcg tcttcttacg tttatctcct
    38101 acttccgata cattttaaac tgtaggaaga ggtcgctata tttccctgtc catttatggt
    38161 caaatttctc ataaacttct aggtgtttca tggtttcaac atcgggatag aaggccttat
    38221 cttcctttgt ttcctctggg agcaattcct tcgctggtag gtttggtgtt gaatagccga
    38281 catactccgc attttggaga gcattttcag gtttcaacat aaagttgata aaggcatagg
    38341 ctgagtcttg atttttaact gttttgggaa tgaccatatt gtcaaaccaa agattgctgg
    38401 cctctgtcgg taccacataa cgtagatttt catttttttc taacatttgg ctggcttcac
    38461 cagagaaggt cacgccgatt gcaacattat tctgaatcat gtagcccttc atctcgtccg
    38521 caacgatagc cttgatattt ggagtcagtt tgtagagctt atccactgtc tcttccaact
    38581 gctgcggatc cttggagttg aggctgtagc cgagggaatt gagtcctagt cccagcacct
    38641 cacgcgcccc atcaaaaagc atgatagaat tcttatactc cagcttccaa aggtcatccc
    38701 aatgctcagg cgcttcatct accatggttt cgttgtagac aattcctaag gttccccaga
    38761 agtaagggat ggagaattta ttacctgggt caaaggactg gttgagaaac tctggtccga
    38821 tattttcgat tccttcaatt tttgaataat caagcggaac caagaggtct tcgtccttca
    38881 tcttgttaat catgtattca cttggaatgg caatatcgta ggtcgttcca ccctgcttta
    38941 tcttagtgta catggcttcg ttggagtcaa aagcctcgta ctgaacttga attcctgttt
    39001 cttctgtaaa ctgagtcaag agttcaggat cgatatagtc tccccagtta tagataacca
    39061 atttttgact atctcgacta ttgattttac tatctaaatg agtcgcaatt ccccacaaga
    39121 caaggataat cgctgcaatt cctgctaaaa atgaatagat ttttttcatg cttgctcctc
    39181 cttctcacga gagataaagt aataacctac aactaggata atactaaaga gaaagactag
    39241 agcagaaagg gcattgattt ctagcgaaat ccccttgcga gcacgagagt aaatctcgac
    39301 tgatagggtt gaaaagccat ttcctgttac aaagaaggtc acggcaaagt catctaacga
    39361 ataggtgaag gccatgaaat aaccagcaat gatagacgga gtcaggtaag gaagcatgat
    39421 ttccttaaac atctgaaatt gactagctcc caagtcatag gccgcatgaa tcatgtcgcc
    39481 attcatttcc ttgagtcgag gcaagaccat caagaccacg ataggaatgg agaaggccac
    39541 atgactagat agaacggtca aaaagccaag tgaaaacttg agttgggtaa agagaatcaa
    39601 gaagctagca ccaatcataa cgtcaggcgc aaccatgagg atattattga gtgatagaaa
    39661 ggcttcttgg tatttcttac gagactggta gatgtaaatg gcaccaaaag tcccgataat
    39721 ggtcgctatc aaggctgata ggaaggccaa gaaaaatgtc tgagccaaaa tcagcatgag
    39781 tctcccatct ccaaacatgg tttcaaagtg agtccagcta aaacctgtaa agctattcat
    39841 atcatcacca gcattaaagg catagccaat caagtaaaag ataggcaggt agaggaccag
    39901 aaagaccagt cccagataaa ggttggcaaa ttttttcatc gttctctcct ttccttagtc
    39961 acccacatgg tgatgaacat ggtcaggatg agaatcacac cgatagttga acccatacca
    40021 tagttgtcat tggttagaaa attctgctca atagccgtcc ccaaggtgat aacgcggttc
    40081 ccaccaatca aacgggtcag catgaagaga ctcaaacttg ggataaagac cgactgaacc
    40141 ccacttcgca caccgttcat agatagaggg aagatgacat gacggaaggt ctcccactta
    40201 gttgcaccaa ggtcgtaact agcattgatg agattattat ccatatcgtc taagacattg
    40261 aaaatcggca aaatcataaa ggggagctcg atgtagcttg cgacaaagat aaaggaaaaa
    40321 tcggtaaaaa gcaactgttg tgaaccaatt ccgataaatt ccaagaattg gttaatagag
    40381 ccattttgac caaaaatccc gataaaagca taggctttaa ggagcaaatt gatccaggta
    40441 ggaaggataa tcagcatgag ccagagttga cggtgcttga gacgggtcaa aaagagggct
    40501 gttggatagc tgataagcaa ggtcacaaag gtcacaatcc ctgcataaag cactgagttg
    40561 aaactcattt tgaggtaggt caagttttgt gacgcaaagt aagatttata attttctaaa
    40621 ctaaactggc cttcaatgtt gaaaaaggat tgtccgaaaa tcaagaccaa gggtgccaat
    40681 acaaagaggg caatccaaag catgtagggc actacaaaga gtttagagct tgttttcttc
    40741 atctctttcc tcctcgatcg cattgatcag acctgcttct tgctcttcga tttccacgta
    40801 ttcttcgata cgagcatcga actcttcttc ggtttcattg agacgcatga tgtggatgtc
    40861 ttctggttca aagtccagac cgatttcctc acccacgatg gccttacggg ttgagtggat
    40921 catccattca tttccaagtt cgtcataggc gataatttca taatgcaccc cacggaagag
    40981 ctgggtatcg accttaactt ggagcttgcc ttcttcagga agggtaatgc gcaagtcctc
    41041 tggacgaata acgacctcaa caggttcatt tggcttcatc ccaccatcaa ccgcttcaaa
    41101 gcgtttgccg ttaaattcga ccaagtagtc ctcaatcatg gtacctggca agatgtttga
    41161 ctccccgata aaggtggcaa caaagtggtt gattggctca tcgtagatgt ccacaggggt
    41221 tccagactgg acaatctcgc catcattcat aacgaaaatc cagtcactca tggcaagagc
    41281 ttcttcctga tcgtgagtga caaagacaaa ggtaatgccc aatcgttgtt gtaattcacg
    41341 caattcgtac tgcatgtctg ttctcaattt caagtccagc gctgataaag gctcgtccaa
    41401 caagaccaca cggggttggt tgatgatagc acgggcgatg gccacacgct gacgttgtcc
    41461 tccagaaagt ttgcggatgg aacgtttttc ataaccttcc aactgaacca tcttgagaac
    41521 ttccgctaca cgctgctcaa tttctttctt atcaatttta cgcaagcgaa gtggaaaggc
    41581 aacattttca aacacattca tatgtgggaa caaggcatag gattggaaga cggtatgtac
    41641 gtcgcgcttg ttggttggaa tatcattgat acgaacaccg tctagcatga tatctcctgt
    41701 cgtcgcatcc agtaaacctg caataatgtt taggatagtt gatttccccg aaccagatgc
    41761 acctagaagg gtgtagaatt tcccttcttc caactcaaag ttgatgtctt tgagaacctt
    41821 ggtgttgctg tcttcaaaaa ctttagagac gtttttgaat tcgataattg gttttttcaa
    41881 ttggcataaa ttccttcttt ttcatagatt aaccgatcgg ggctctgtca ggtccccact
    41941 acctcttgca gggagtaaaa ccacctgcat acatcttcgc taccgatagg ctttcaccca
    42001 agatccggac ttctctttca agcgtaatac ctgagtgttc cttgactttt tcgataaccg
    42061 attggatcaa gtcctcgtag tctttggccg ttccatctgc gacattgatc ataaatcctg
    42121 catgcttttc tgacacttct acgccaccga tacgatagcc tttcaagcca gcttctgaaa
    42181 ttaactgacc tgcaaaatgc ccgactggac gcttaaagac cgagccacaa gatgggtatt
    42241 ccaaaggttg cttgagttca cgtaggtgcg tcaagcggtc catttcctgc ttgataacct
    42301 gatgggttcc tggagctagg gcaaatttaa ctgacaagac aactgcacca gactcctgaa
    42361 tagctgaatg gcggtaacca aaagccaagt ctttagcaga cagggtttcg atttctccat
    42421 ccttggtcaa gaccttacaa gactgcaaga tgtgagcaat ctcgccacca taggcacccg
    42481 cattcataaa gacagcaccg ccaacgcttc ctggaatacc acaagcaaac tcaaagccag
    42541 ttaaactatg acggagggca atgcgagttg tttcaatcaa gttagcccca gcttctgctt
    42601 caatggtata gccatcaaca gaaacgttat tgagcttgtc acacaagatg acaaatccac
    42661 gaatcccacc atcacgaacg atgatattgc ttgcattgcc aagaaccatc caagggatat
    42721 tttcttggtt ggcaaatttc acaacgcgag ccaactcaaa acgatttcgt ggaaagacca
    42781 aataatcagc ctctccacct acttttgtat aactatagct atgcaagggt tccttaaaac
    42841 ggatatcaat tccttctaag atttcaagca ttttttctct tacagacatg tcactcttcc
    42901 ttttacaaaa ttcattccat tataccattt ttagagacat ttgacgacca taaaaatacc
    42961 ttgtttggat tttgcataag aaaaagaggt tccccccttt ttatgatttt ttacaaaaga
    43021 tttccttggt tccataggcg accagaacga gctccagtgc tagaatcact tcaaccaaga
    43081 ctggatttgt caaccagcct acttggaaaa gagatggtgc cagatcaaag aaggcatgca
    43141 agccataggc tgctaggaga taaatccatt tcttctggcg aacagcttgg taaacccaaa
    43201 ctgtcaaaag taattggaaa ccaagcgcca agattcgctc aaaaccaagc aaataaatct
    43261 gccagaccga aagtgactga atggttttta acatattttc agacagtaat tgcataacct
    43321 gtggattctg agtttgaact gccgaaagaa cgatgtaaag attgagtaaa ctaataaggc
    43381 ctagaaaaat caactccaag ccaccatgcc ctaggccata ggccaaggca tctgcctttt
    43441 ccaaacttct ctttttctcc aaccatttga agaaaacaag acgagccgtt tcctcaaaaa
    43501 atgctgccat ggctaggcca tagataatat agataagcgg atgatcttgc aagagggcaa
    43561 tactaccgtc tttttgagga tgcaaaatca agatatgcac cagtttttcc aaaatctgcg
    43621 aagagacaaa gaaagcgact gcacccaagc ccaagacagc tagattaatc tggtatttct
    43681 ttttggcaaa ccaaatgctt cctatcagaa aagctagcaa cagcaacatg gtaataatga
    43741 tatgaatggt cattttcttc tcctattctg ccttttcaat atcttttttc atctcgtcaa
    43801 cattgaactt agcaaacaag tattgacggt cttggactgg gaaacgttgg tccaactggt
    43861 caactgctcc cacctcgata atgccttcct tgatgacaaa atccatgaca tgtccaccga
    43921 aggtcaaatc atctgatatg aagtgcagat ggtagcctgc cacactgacc ccatggaaaa
    43981 tctcaggcgt ccagaaacca acaatagtcc ccgcaacatt gtcacgacta tattccggtt
    44041 gatgggttgc gacatcagca aacttggtat cgggtgttga cttaggaatc atacgcacat
    44101 gcatatgtga aaattccccc cgaatcttga tagagcggaa aagattttcc ccatcataat
    44161 aagactcaat tcgttctttc aattccttgt ctgtcatctc aaagcgctgg cggaaaatga
    44221 cctctgcctg atgcggtacc actgcagcgt aaggaataag ggcatctggt gacacttcca
    44281 caatttctgg ctggtctcct gaccctttgg cctgataagc cttgccatcc aagacaatca
    44341 attccccatc aatggaatcc aaggttccca aaccaaggtc accatgttct agcaattctc
    44401 ctactgtcat agtaccacca taaaggccag ccatcaaggc tccaagagta ttgtattgaa
    44461 ataatttcac tggttcctgc acgttcttat ccattcactt tcttgtctgt tattctataa
    44521 atcttactcc taagtatacc acatttgccc ctagatgtga acgagagaaa cgctctagac
    44581 attgccaaga aggaaaaaaa agggtacaat gtaacaaaat caagggaggt ctggaatgaa
    44641 gaaacaaagc aagtacaaag aggtcgtttc ctatctgaaa aatggtatcg agtctgaacg
    44701 atttccgacg ggtagtcgcc tgccttctat ccgtcaactg agccttgact ttcactgcag
    44761 caaggacacc attcaacgag ccctgctgga attacggcac gaacaatacc tctatgccaa
    44821 gcctcagagt ggctactatg tattagaaca agggcaacat caagacctag aaatcgaggt
    44881 taccgacgaa catgccagtg cctatgacga tttccgactc tgtgtcaatg aaaccttgat
    44941 tggacgagaa aactacctct tcaactacta tgacaatcaa gaaggattag aagacctaag
    45001 acagtccatt cacaaactcc tatttgagca agctctctac tgcaaggcta accaactagt
    45061 actgacttct ggaacccaac aagccttgtt tatcctctct caaatatcct ttcctagaca
    45121 agccaaggaa atcttggtgg aacagccaac ctaccatcgg atgaatcgcc tcttgattgc
    45181 acaggggctg gactatcaaa cgattgaacg aggcattgat gggattgact tggaggagct
    45241 ggaaggccac ttcaaaacag gaaaaattaa atttttctac accattccta gatttcacta
    45301 tcctctggga cattcctatt ctgagcaaga caaacgatct attcttaact tagctgccaa
    45361 gtatgatgtc tatatcgtag aggacgatta tctgggtgat ttggactcca agaagggcca
    45421 aaccttccac tatcttgata cagaggagca tgtcatttat atcaagtcct tctcgaccag
    45481 cctttttcct gcccttcgta ttacagcact cattcttcca aatgctatca aagaagcatt
    45541 tgtggcctac aaaaatatcc tagactacga cagcaacctc attatgcaaa aggccctgtc
    45601 actctatatt gacagtcaat tgtttgaaaa aaatcgtttg gctcgcttga ccaatcatga
    45661 atcttaccaa aaacaaatcg aggaaaggat aactaaaaca ccttgtcccc ttcctcatta
    45721 tcccctacac gatggtttat tgctagacct gagacagtat cctaaaatcg ccagtctcaa
    45781 acacagtcaa ctgggcttgg acttctttga agaggcctat ttaagcacct gtccttatca
    45841 atttgccaag gtgtccctag acaatctgga aaatgtttta aactatttaa aagcagaatt
    45901 ggaatgacat ccaactctgc tttttcttat tcttcaactt cagttagact tgctgctttt
    45961 tcaagatagc tttggtaagt tccttcattc ttaagttttt ggatgacctt gtctaccact
    46021 tctttcaaat catcactatt ttttctaaga gcaacggcat tggcgtcgcc gtccttcatc
    46081 ttcaagctga cagttgcgac agctaagcca gcgtttttag cagcataact aagtgcaaca
    46141 ggctcatcca tatgaacagc atctactttt ccaacctgca attcattgac tgcttcaccc
    46201 atattagtta gggaagttaa ttgagctttt ggcaattgtt ccttgaccat tgattctgga
    46261 acagtccctt tttgggctgc aatattagca ctttctaggc tagttaaatc cttgtatttt
    46321 tccacatcag ccttacgaac caagaaacta atcttgtttt catagtatgg gattgaaaaa
    46381 tcaaagactt cttttctctc gtcagtagca ctaattcctg caactgctag gtcagcctta
    46441 ccagtttgaa gactggtcaa aacattgtca aaactcatgc ttgagatttc caacttaacc
    46501 ccaagttcat cagcgatagc ctgagccatg tcgatgtctg caccgactac ctggttcttt
    46561 ccatcaacca atgattgaaa ttcaaagggt gcatagtcag gactggttgc cacaactaat
    46621 ttcccttttt gtttgatagc atccacagca gactgagaac cattagaacc tgactgacaa
    46681 gctactaaga agaaacttgc aagaaaatta cataaaacaa atatccattt ttttgatttc
    46741 ataaataaac aacctctctg ttaattttgt ataattataa cgatatccaa gttacttgtc
    46801 aagtgttttt taaattttta tctcaaaaat attttttcgt tcaaaaaaag gagccatcag
    46861 ttgatttcaa gctccttttt atacagaatt aaactatttt ataattcgac aatcttacct
    46921 gtttcaaagt agacaaccca ttcacagata tttttagcat agtcaccgat acgctccaag
    46981 taggaaataa cttggaaata atcacgaccc gtaacaatgg cttctggatt tttcttaatc
    47041 tcttcagtcg caaggtcacg gatagtttca aaatagtggt taatttgctc atccatggag
    47101 gccacccggt atgcgtcgtc aacagaacca ttaagataaa gatcaagtgc tgcttcaaca
    47161 acgcttttaa cttcacgtcc cattttttta atttcttcct ctacagctgg gatgcgttct
    47221 tcccccttca tacggatggt tgcctgggca atggctacag cgtgatcccc catacgctcc
    47281 acatctgata cagccttaag gacagtcaag actgtacgca aatcttgaga gactggttgt
    47341 tggagtgcga tcatttcaaa tgatttcttt tccagtttca cttcgtattc atttacttct
    47401 gcatcatctt cgatgacctc ttttgccagg tcacggtcat gcgtgacaaa agcacgtacc
    47461 gtacgattga tttgtgagag cacttcttgt cccatagcgt agaactggtt atgtaatttc
    47521 tctaaatctt cttcaaattg agatcgtaac atctttcatc tccttatcca aattttcctg
    47581 taatatagtc ttccgtttcc ttgtgttggg gatcaaggaa catctgcttg gtatcattaa
    47641 attcaatcaa atctccatct aggaaaaatc ctgtcttatc agagatacgt gaagcttgct
    47701 gcatggaacg ggttaccaga agcatggtgt acttgtcttt tagaccatac aaggtttcct
    47761 caattttacc agctgaaatc ggatccaaag ccgaagttgg ctcatccaag aggatgattt
    47821 taggactagt tgccaagaca cgggccacgc agacacgctg ctgttgacca cctgacaatc
    47881 caatagctga atcatataga cgatccttga cctcatccca gatagaggca ccttgcaagg
    47941 ctttttctac ggcttcatcc agaacctgct tatccttaat tccattgata cgaagcccgt
    48001 agacaacatt ctcatagata gtcataggga aaggattagg ttgttggaaa accattccga
    48061 tttccttacg taattcaacc gtatctgtac gcggactgta gatgttgtga ccattgtaca
    48121 ccacggatcc agttgtggtc acctctggat tgagatctcc catgcggttg agagacttga
    48181 ggagggttga cttccctgat ccagatggac caatcaaggc tgtaatttcc ttaggttgga
    48241 aagataggga aacactattc aaagccttct ttttattata ataaacggac aggtctgata
    48301 cctgtaaaat cgcatctgtc atacggtttc ctttctaacc aaagtgacca gatacatagt
    48361 cattggtgga ctgtagcttg gcattttgga aaatagttgc agtcttgtca tactcaatca
    48421 aatcacccaa gtaaaagaag cctgtatagt cacttgcacg agcagcctgc tgcatattat
    48481 gcgttacaat gatgatggta aagtctttct tgagctcaaa catggtctct tctagttgca
    48541 tggtcgcaat cggatccaag gctgaagctg gctcatccat taagaggata tctggcttaa
    48601 cagagatggc acgagcgata cagagacgtt gttgctgacc acctgataag gtcaaggctg
    48661 acttgtggag atcgtcttta acctgatccc agagggcagc ctgacgaagg gaggtttcta
    48721 cgatttcatc taggacttgc ttatccttaa ctccagcacg ttcatgcgca aaggtaatat
    48781 tacggtaaat tgacttagca aatggattgg ggcgttgaaa aaccattcca atgtgtttac
    48841 gcatttcata aacgttgatt tctggacggt tgacatcaat tccacgatag agaatctgcc
    48901 cagttacttt agcaatatca atagtatcat tcatgcgatt gagactgcgt aagtaggtag
    48961 atttccccga tcccgacgga ccaatcaaag ctgtaatttt atttctttca aattgcatat
    49021 caatcccctt aatggattca tttttaccat agtaaacatg gacatcctta gtagaaaggg
    49081 ctactttttc ttcaggaaag gtaaggatat gcttctcatc ccagttatat gttgacatgg
    49141 cttctccttt aggcagcggt taatttcttg tgtagatagc ttccgaactt acgagctcca
    49201 aagttaaaaa tcaggataaa gatcaggagc acagcggcag aacctgctga tacaatggtt
    49261 ccatctggaa tagtgccttc actattgact ttccagatat ggacagccaa ggtttctgct
    49321 tgacggaaga tagagatggg gctagtcaca ctgaggatat tccagttaga ccagtcaaga
    49381 gctggcgccg attgccctgc tgtatagatc agagctgcag cttcgccaaa gatacgacca
    49441 gatgccaaga cgacacccgt tacaatacct ggaagcgctt ctggaataac aacatgaacc
    49501 actgtctccc agcgagaaat cccaagagcc agaccagcct cacgttgggt atggtgaacg
    49561 tgtttcaaac tatcctctac attacgcgtc atctgaggca agttaaagac tgtcaaggcc
    49621 aaggcacctg aaatgattga aaatccatac tcaaactgga ctacaaagat caagtaacca
    49681 aagagaccca ccaccactga tggtaaagag gacaagattt caatacaagt ccgcacaaag
    49741 ttggtaacag gacctttttt agcatattca gccaagtaaa tcccagctcc catagaaaga
    49801 ggtacagaaa taatcaaggt aatgaccaat aggaaaaagg aattgtaaag ctgaatgcca
    49861 atcccaccac ctgcttgaaa agcagaagac cttccagtca agaaagacca agagatatgg
    49921 ggcaagcccc gaaccaagat atagagaatc aaggaagcca agattgtcac aatgatgcta
    49981 gcaatcgtat agaggacagc tgttgcaagt ttatctaatt tcttagcgcg cataattttt
    50041 ctttcctctt tctttcgtaa tcaatttaat cacactgtta aaaactaaac tcatcaagag
    50101 cagtaccaag gccagtgacc agagaacatt attatttaca gttcccatga cagtgttccc
    50161 aattcccata gttaatatag aagttaaagt tgcagctggt gtggtcaagg aagttgggat
    50221 aacagctgag tttccgacaa ccatctggat agctaaagcc tcaccaaagg cacgcgccat
    50281 cccaaagacc actgcagtga aaataccaga acgggccgcc ttcaagatca cacgccagat
    50341 agtctgccag cgagtggctc ccatagcgaa actggcttca cgataataac gaggaaccgc
    50401 acgcaagcta tccgttgtca taaaggttac ggtcggcaaa atcatgacaa agaggacgga
    50461 aatccctgac aaaatcccaa aaccagtccc accaaagaca ctgcgaacaa agggaacgac
    50521 gacttgcaag ccaataaatc catacactac tgaaggaatc ccaaccagga gttcaatagc
    50581 tggttgcaaa atcttcgccc cttttggtga tacttcggtc ataaaaactg ctgcaccaat
    50641 agcaaagggt gttgcgataa gggctgagag aatggtaacg ataaaggaac ccaaaatcat
    50701 aggaagggca ccaaattctt tactagaagg attccaagtt cctcccaaaa gaaagtcaaa
    50761 gatattcaca ccattgacaa agaaggtcga caagcctttt tgcgctacga aaaccaaaat
    50821 catggccaca aggatgacta tcaaagaaag acaggcaaag gtcaaacctt ttcctaattt
    50881 ctccagacga gaattctttg atggaagcaa cattttctta gctaattctt cttgattcat
    50941 tattgtctcc cttccaacac tgtcacagtt ccggcagcat ctttttcaac cttcatttcc
    51001 ttaatcggaa tatacttcaa tcctttgaca atcccttctt gggtctcatc cgagagaaca
    51061 aaattgagaa attctgcagc caactcattg ggctgcccca atgtatacat atgctcataa
    51121 gaccacaagg gccaattatt gctacttata ttttctggac ttaagtcata gccattcaac
    51181 ttcatgcttt tgaccgaatc atctatatag gtaagagata aataagagat agctcctgga
    51241 ctttttgata cgattgattt taccgctcca tttgaatcct gctcctgact ttgcatggca
    51301 gactgacctt ccataatgac agtatcaaag gtagcacgag agccagagcc ggctgcccga
    51361 ttgataacag agatgggtaa gtccttacca ccaacctctt tccaattggt tacctcacct
    51421 atgaagattt gacgaagttg ctctgtcgtt aggttatcaa catcaacctc cttattgaca
    51481 atcagagcca agccagctac cgcgaccttg tggtcaacaa gagcagaagc atcaattccg
    51541 tctttttcct cagcaaatac atctgagttt cctatatcaa ctgccccaga ctgaacctgg
    51601 gacaagcctg taccagaacc tcccccttgg acattgaccg tttttccaac atgaatcgtg
    51661 ccaaattcat ctgccgctac ttcaaccaag ggttgcaagg cagttgagcc aacagccgtt
    51721 atggattctc cacgatcaat ccagctagca cagcctacta aacaagccgt cagccaaaaa
    51781 gcgataagag acagagcaag cttttttctt tttttcactg tttttctcct cgaaaataat
    51841 tatgaatact gtgaattttt taagtagttc tttatgagtt gacgcatgaa ttcttaccaa
    51901 atttctgcgc aattgattat ttatataata taggctatat tactctttcc taacctcctt
    51961 ttttcatatg tggataaaat ctcttgtcta tcccttccac cattgtcacc cattatagtc
    52021 atttcgtgtc tctttttccc ctttttaatg caagggaaat tactctcctc agatgataat
    52081 ccaaaagcta gaaaggtatc tcaaacctct ctactctccc agactagttt acaactaaaa
    52141 ggaaaagatt ctattttatg agaaatctag tttacaagcg gtaagaacgc taataactaa
    52201 acttcttgta ctctttgaaa atctcttcaa accagtgttt tgagctatct atggctagct
    52261 tcctagtttg ctctttgatt ttcattgagt agtaaaacta catgtaatgg caatcaagat
    52321 atcaagaatc atcctactaa aaaaatccat actttcacta taacatagaa taagatattt
    52381 gactagcatt ttcatttgaa tctgaggcct tttggaaaat aatttttcaa aacatttcca
    52441 gtaacctttg caaagcccaa gccattgcct ttaaccaaaa cttggtacca accatttggc
    52501 agactttctg ccagctgaac gatttctcca gccgcatact tgacaaacgc ttcttggcca
    52561 atttcaaccg actgttcgac ctgactcggt ttcaaggcta aaccaagagc gaaactgggc
    52621 tcaaagcgtt tcttcttaaa agtgcccaga tgcagtccat tgcgagcaat cttgagcttc
    52681 cctaaatctg gcaaaagttc tggcaagaga taaagctggt ctccaaaagt ctgcaagata
    52741 cccggtagat tgaccttcaa atggttttgg gcaaattcct gccacaaggc aacttgttca
    52801 cggctgaggt tactcttact tgccttaaat ttaggagctg gattgttacc cttaaactgt
    52861 agatgggcaa caaactgacc ctctccctta aactgatgag gatacatccg agccgtttct
    52921 ggcaggtcaa taccagctac cattccattg atatgctcta ctggcaacaa gtcaaaatca
    52981 tactcttcca gcaaccaatt gacaatctct tcgttttcct cgggtgccca ggtacaggtc
    53041 gaataaacca gatgaccacc ttcagctaac atggtcactg catcctccag aatttctctt
    53101 tgcaagctag cacattgact cggataatct aagctccaat agtccataac atcaggttgc
    53161 ttacgaaaca ttccttcacc agagcaaggg gcatcaagaa cgattaagtc aaaatagcct
    53221 ttaaagacct tgaccaagcg gtcggcagat tcattggtca ccacgacatt tgtcgctcca
    53281 aaacgctcca tgttttcaac caaaatctta gcccgtttgc ttgaaatttc attggaaaca
    53341 agtagcccct cccctgctag ataggctgcc agttgagttg atttgccccc cggtgcagca
    53401 gccaagtcca agaccttcat accaggactg ggttgggcta cttgagccac catttgagca
    53461 gcaggttctt gcgaataaac taaacctgta gcatgctcag gcgatttccc tgaaaccttc
    53521 ccatagtggc cccaaggggt ttgagtaatg gcatcagaaa aggaaagttg ctcttctttt
    53581 aagggattga cccgaaaggc cgaaaccgct tcctcctcaa aagaggcaag aaaatctctt
    53641 gcctcatctc ctagtatctc tttatatttt tcaacaaatc cttctggaaa ttgcatttaa
    53701 gttcttttcc tttcgtaaat ataggactga atttcctcct gcatctcaag aggcaccatc
    53761 atgaccggct gtctggtttg aaaatcagga gcttcaccaa aaagggtcac aacccgatag
    53821 cccagacttt cccctaaaat actagctgcg gcataatccc atggttgcag ataagtgaga
    53881 taggtcaaca aacgccctga caaaatcttg gcaaaactaa tggccgcact tccatagaca
    53941 cgaacaccaa gaaccgatcg gctcaaatca gccagccccc attcattggt ttccagcata
    54001 ccactattcc ctgcaatgag aaaatctcca agtggtttag ttttaaaagg agctaggggc
    54061 ctatcattta gacaaactgg aaattcccca ccaccgtggt aacaatcccc tttgaccaca
    54121 tcataaatca gaccaaactg tccctgacca ttttcaaaat aagccatcat aacagcaaaa
    54181 tcttcctgct gggctacaaa attattggta ccatcaatgg gatcaatgac ccaaaccttg
    54241 ccctcttgaa ccgaggctcg cagacaacct tcttcagcac aaatcttatc ctcaggataa
    54301 cgggacaaaa tctcaccaac caagagttcc tgaacttctt tgtccagtct ggtcaccaaa
    54361 tctgttgaag aggacttggt ttcaacacgc aagtcttcct gcatatggtc aagaatgtac
    54421 tggcctgctt tcttaacaag ctctttagca aattcaaatt tactttccaa gagaaatctt
    54481 tccttcccct ttttctttgg cagcctgaac tgctcggtaa agtgaatagc cactaaccgt
    54541 ttcaaattct cgtcccaaac gtttctcttc gctcttgctt ggcacgaccg ctttgaatcc
    54601 cttataggag tccagtaact ttttagcctc tactttgcct tcataggcag cttcaacatc
    54661 attaaaaaaa gaaagcactg aagcaagttc ttcagtgctc cacgacaaat ctagtgggta
    54721 actatactgt ttgttcatta actaatacca gctctcattc ttgcttcttt tagttcttgc
    54781 ttacgataac tacgagggag aaaagcacga atctcatctt cattaaaacc gatttgcata
    54841 cgcttggcat caataataat tggacgacgc aaaagactag gatactgctc aatcaaatga
    54901 agcaattccg ataccgaaat actctctaca tcaatattca atttttgaaa aatttttgaa
    54961 cgagttgaaa tgatgtcatc agtaccattt tcggtcaagg aaaggatgtg ttgcaattct
    55021 tttcttgtta aaggactggt cataatattg tgttccacaa agggaacctt atgtttttct
    55081 aaccaggcct tagccttacg acatgatgta cagctcggtg atagaaatag tgtaatcatg
    55141 cttttctctt cttatctata ctttgctact tctattatac aaaaaaataa ggcgcttgac
    55201 tagggatttt tagaaaaaaa gcctattttt tcaagaaaaa taggctgttt gcgaacgatt
    55261 gacacaattg gatttggtta attcactctt aacgatggtt ttaaacgata tatattttta
    55321 tatatgcaaa ttaaaaacat ctttcatttc acttcctacg acttttcaga cacagatacc
    55381 caaagaagct ttcatagagg gcaaaaaaga ggaggaaggc atgaagaaag aaggtctctg
    55441 gcaaaatcat aataacagga tccttggctg gatcaaaaag ccaggtatca tctcccacaa
    55501 agagaatttg atggaaaaga gtaaagaatt ggtcaaaacc aatcaaaact cccccaagtc
    55561 caatcatcac aggtaagact actagagtca ggagactttt tcgataaaga gacaaaaagt
    55621 cctttttcac aatcctattg acaaagacat agaaacttgg cagtgtcact agagctacta
    55681 gctgaaccaa atgaaagaga ttcttgacca ctgcgaaatg gtgcagacca gctgctgacg
    55741 aacgaaaatc aggcatctgt aagacctgac taaaaggatt ggtcagataa ttcatcaaga
    55801 tatgaaaatt gtattgaatg gtttctggtt ttagatagac tcgattcgtt aagtttagcc
    55861 actgaatctc cataggatag aaaatccaag ccagataaat ggtcagaagg attgagaggg
    55921 agaggagaaa gagcatagag ccccaaaagg tcaatttagt tttcatcaaa atcccactcc
    55981 gcaaggctag aaaccacatg tgtcggtgcg attggcaggc cagctacttc ttctgccttg
    56041 gtaaaacctg tcgtcaccaa gagtgttgga atgccattgt caatcccagc ccggatatca
    56101 gtcaaataat tgtccccaac catgattaac tcttcacgtt ccaaacctaa gtgctcaacc
    56161 gccttgtcca taatgatggc atttggtttt ccgatataaa ccggcttcac tcgtgtcgct
    56221 acttcaagca gcgtaatcag tgagccagca cctggcaaaa gaccacgttc cgtcgggatg
    56281 ttgaggtcag gattggttcc gataaaatgg gcaccctttt gaatagcaag agttgctgtg
    56341 gcaaattttt catagtcgac ttgccaatcc agaccaacta ccacgtaggc agggttttcc
    56401 ttgtcttcca cataaccagc cgccttgatg gcttccttga gtcctgcttc tccgacgaca
    56461 tagacggtct tttcaagccc caaatcattc atatagtcga tggttgccaa agtcgctgtg
    56521 tagacagtcg atagaggcgt atcgatatta aaattctgag ccaacatctc cttaacactc
    56581 tctggagtgc gggttgtatt gttggttaca aagagatagg gaatgtcccg cttttgcaat
    56641 tcatgaacaa aagtctctcc agcagggatt cggtctttcc ccttataaat ggttccgtct
    56701 aaatcgatta aatagccttt atatttcatc tatttctccc taaacctttt ttatttcttg
    56761 ccaagtaatg attgcttggg cattgataac cccatcactt gtaatttcat gcttgctttc
    56821 cagtccagtc cgttcaacag ccgatgtaat caccccacct ggtcgaactt ccttgacata
    56881 cttgaggttg attttcttgg gaatatagtg ggtcaaaaaa tccgctccca tgacctcaaa
    56941 aatccagtcc aagtatttac tgttattgac atgaccattc atatccaagt cgtaaaaacg
    57001 aacatggtaa tccttgctga tcggctcttc caaggattca tacttcggtc cacggataag
    57061 ttttttatca aaatcagact ggtaaggagc cacaatctca ggttcaacag catggacttt
    57121 tcgactgtcg cggtccatga gaacaaaggt cgccatcata tggatgagct cctgccccgc
    57181 ttcattataa atagtaaagc gacggtagca aaaaagtcga ttgtagctca aggcttccgt
    57241 ttcgatggta atttcttccg caaaacgagg caaacgaacc acctcaatat catattctgc
    57301 gataatccag accagattat agtcttccaa aatggcctta tcactaactc ccagttcaat
    57361 cgattgcatc cctgaaactt gcagtgacag caaaatcaca tctggaagtt tgatatgacc
    57421 gttcatatca gccatatcaa aaggaatttt cattttcatt tgataagtta agcccatgat
    57481 cctactccaa aataaatcgt tctgctacag tatctcccaa aaagagacct ctctttgtca
    57541 tgcgaacgtg gtcaccctca atctgcatga ggccttgttg aaccaaatct ctgacaattt
    57601 ctccataaag tccagcaaaa gactgtccaa atttttcctc aaatcgcgcc atggaaaccc
    57661 cggatttctt gcggagtccc aagaacattt cttcttccat ttgctccttt tgactcaggt
    57721 gatcttctgt aatacaagca ttgccttcct caaccgcact gagataatga cgaatgggac
    57781 catgattttt atagcgtact ccattgacat aaccagatgc ccctgcacca ataccatagt
    57841 attcagcatt gtcccagtac atgagattat gacgactttc aaaaccgggt ttggagaaat
    57901 tagaaatctc ataatgctca aaacccgctc gctccagctc tgcaatgatg tactcaaaca
    57961 tctccgcttc tagttcctcc ttaggcagag gcaatttccc acgtcgcatc cggttcataa
    58021 agaccgtatg gttttctaaa atcaaactat acaaactcat gtggggaata tccaatccaa
    58081 tggctttagc cacattttcc tttacttgct ccatggtctg accaggcaga gcataaatca
    58141 aatcaatgga gatgttgtca aaaccagcca gtttcaggcg atcgatattt tcataaatat
    58201 ccttctccaa atgactgcgc ccaatctttt tcaacatctt atcatcaaag gtctggacac
    58261 ctagcgaaac acgattgaca gccgaatttt tcaaaacagc tatcttatcc gcatccaaat
    58321 cgcctggatt ggcttcaatg gtcaactctt ccaagacaga caaatccaag tttttagtca
    58381 agccattcag taacacctcc agttgcggag ccgacagggc tgtcggtgtt ccaccaccga
    58441 tataaagggt tgacaacttt tcaatatcat aagaacgaaa ctcttccagc agatgctcta
    58501 aatagctgtc gactggctga tttttgatga agacctttga aaaatcacaa taataacaaa
    58561 tctgggtaca aaatgggatg tgcacatagg ctgacgttgg ttttttctgc atagtaatta
    58621 ttataccaca aagactagat tccagataaa aatcaccatc cccagataca tagtccgtcc
    58681 ggagatggtg atggtttatt cttctgttat atgaatcaca atctcttctg agtcatcaag
    58741 agcttcggct ttttcttgcc attgttcctt gagattattt aattgatttt ttgatgcttc
    58801 tgtcgcttga aaagcatagg atttagcttg agcaagtata ctgtccacag tgatttcacc
    58861 tgactcaacc tgttcttttg ttttcagaac aaaatctgta gcctgctcct taacttctgt
    58921 cagtttttca cagacttgct ccttggcata ctccggatct tctctcaaat catctagaaa
    58981 atcttgagcc tgactgcaaa cttgtttgcc cttatcactt gttaaaaaca aggcaagagc
    59041 tgcacctgaa accgttccta aaaggattga ggataattta cccataagga ttctcctttt
    59101 ttattttttg aaaaatttac ttgcaagacg aagagctgac agacttgcac cagtcttgag
    59161 tgtttttgaa ccagctgatg aagctttctt gctcaagaca cgcgcatggt cattgaggtc
    59221 tgaaacagat agagataaat ctgcaacagc actgaagagt ggatcaatcg tagccacctt
    59281 gacattgata tcatctgcca agacattgac cttagccaac aactcattgg tgtgatgcaa
    59341 ggtcacatcc acatctgaag tcaaggtttt aatcgtcttt tctgtttcat cgatgacacg
    59401 accaagcttt tgtacagtaa tgatcagata gaccaaaaag acaatcaaag ctagggcaac
    59461 aagaatatat gcaacttcta acatttagtt ttcctcctct gtaatatagt aaggggcctt
    59521 ctttcgattt tgataaataa cgatcattat accgagaccg ataaggacaa ctgacagcca
    59581 ttgggacact cgaagtccga agaacatgag actatctgtt cgcatacctt cgatgaccat
    59641 acgaccgaaa ccataccaaa tcaagtaaaa ggccgtgata tgacctcgtc tgagactctt
    59701 ccatttccgt ctaaaaatca gaatcaaggc aaagccaagc agattccata gagactcata
    59761 aaggaaagtc ggttgacggt agctcccctc aatatacatc tggtcacgga taaagccagg
    59821 tagataatcc agattatcca ctgttgcacc ataagcttct tggttaaaga aattacccca
    59881 acgccccaaa ctttgagcaa tcataacgct aggcgccgca atatctagaa aatcccaagt
    59941 attgatgagt ttacggtcag caaagatata gagcacaaga gccccagtta tcaaaccacc
    60001 gtaaatggcc aaaccaccat tccaaatggc aaaaatctct cctaaattct gactatagta
    60061 atcaaatcgg aaaataacat agtagagacg agctcctaaa atagccaagg gaaaggctac
    60121 taagataaaa tctaaaatat cgtctggtat gatcttcttt ctaggtgctt ctttcatggt
    60181 caaataaacc gcaagaatca agcctgtcac aatacataag gcataccaac gaatggctag
    60241 gggtcctagt tgaatagcaa ttggatcaag cattttgcac ctcatttcga gcgatgagac
    60301 ttgtcagtcg ttcgtcgaac aaacgggtcg catcaaagcc catttccttg gcacgataat
    60361 tcatggcagc tgcctcaatc acaacagaga tattacgacc tgttttaact ggaatacgaa
    60421 tacgaggaat ggctacgcca gaaacttcaa gttcctctgc attgtttcca agacgatcaa
    60481 aggtcttatg cgtatcgtaa ttttccaaat agacagcaag ctgaacctgt gaagaatcct
    60541 tgacagcact cgcaccgtag agactcataa catcgataat accaacccca cgaatttcaa
    60601 tcaagtgttt caaaatttca gctggttcac cccagagagt aatctcatcc ttggcaaaga
    60661 tatcgacacg gtcatcggct accaaacggt gaccacgttt gacaagctca agacctgtct
    60721 cactcttacc aattccacta tctccctgaa tcaagacgcc catcccataa atatccatca
    60781 agacaccgtg cacactggta cgttctgcca aacgagaatc cagatagcta gataactctc
    60841 cagataaacg actggtagct gcacggctgg ttaaaatagc aatcttacat tctctagcag
    60901 cctttaacat ctcctctgga accaccaaac cacgggcaac aatgactgct ggtgtctcag
    60961 gtagaaacat ttttttcaaa acttcataac ggctgttgga aggcatgctg atcagataag
    61021 accactcctt catccccaaa agttgaatcc gctctggtgt atagtagtca aaatagcctg
    61081 tcatttcaag accaggtcgc gtaatatccg ctatattgat ttccttttca agcaattctg
    61141 gttcaccata gacaatgtct agtctaagct tttcaatcac ttcttttact aaaaccgaca
    61201 tcatttcctc cttcaaatga gttcttctct ctattatatc aaattgtagg aggaagtttc
    61261 agatttttgc aggctttgga gtatttattt aaaagaaaaa ggactagatt tctctagcct
    61321 ttcatttcaa ttagaatttt ttacgtttac gagctacttc tgatttacgt ttacgtttta
    61381 cagaaggttt ttcatagaat tcacgtttgc gtgtttcttg aagagtacca gctttagtaa
    61441 ccgcacgttt gaaacggcga agtgcgtcgt caagagattc attcttacgt actactgttt
    61501 tagacatttt tttcactccc ttcaagttca atatctattt cattctacac gtaaaaggaa
    61561 taattgtcaa gcaaaaatgc ggtttaattt tgattttttc ttccatttat acaagagttg
    61621 aaagcgttca atagaacatt gcttttttat ttttcgagta agctaagcgc ttcagcatct
    61681 gcgatgatgg ttacatcagg gtgattttgg aggctacttg caggtaggtt ctcagtcact
    61741 gggccagata ctgttccggc aatggcttct gctttcgact caccgtaagc aaaaagaata
    61801 atagacttgg catccaaaat gtttttaatc cccattgaaa tagcttgggt tgggacgtct
    61861 tcaatcttgg caaagaagcg tgcattggct tcgatagtag actggtcaag ttctactaga
    61921 tgcgtttgac tgtcaaatgg agtaccaggc tcattaaagc cgatatgccc attgcgaccg
    61981 attcccaaga tttggaggtc aactggatgg tcagccaaaa tttggttgta gcgttcaact
    62041 tcagcttcag cattgtcctt aacaccacga ggcaagaaac tttctttaaa tggtttttgg
    62101 ttgaacaagt tttcttgcat gaagtaacga taagactgtg gattgtcccc atcaaggccc
    62161 acatactcat caaggttgac actggttaga tttgaaaaat caaggttact ctcaacaatt
    62221 tccttgtaaa attcaagtgg gctacttcct gtcgcaagtc ctagagtttg agctccatta
    62281 gccaattttt ccttcaaaat ctcaaaagca acttttccac cttgaacttg gttttcaact
    62341 ttaataactt tcatcttttc atcctccatt tctgtctata tttattatat ggtatagacc
    62401 aatttttgtc aagtgaaaac gatttaattt ctaaaaaaag agcgtccaaa cttgaaacgt
    62461 gttataatgg ataggattag aacttagaaa gaatgaacag atatatgaat acagctgatt
    62521 ttgatttcca cttgccagag gaattgattg cccaaacgcc ccttgaaaaa cgtgatgcct
    62581 ccaaactcct catcgtcaac cgtgagacag gagaaatgca agataaacac ttccactcta
    62641 ttattgatat gctggaacct ggtgatgccc ttgtcatgaa cgacacccga gttctccctg
    62701 cccgcctcta tggtcaaaaa gtggagacag gaagtcatgt ggaacttctc ctccttaaga
    62761 acactagtgg agacgagtgg gaagttctgg ctaaacctgc caaacgcctc aaggtcggta
    62821 ctcgtatcag ctttggtgat ggccgcctca gcgctgtcgt tacagaagaa ttgacccacg
    62881 ggggacgcat tgtccgcttt gaataccaaa gaattttcct agaagtcttg gaaagtctgg
    62941 gagaaatgcc tctgccacct tatatccacg aaaaattaga tgaccgtgaa cgttatcaaa
    63001 ccgtctacgc caaggaaagc ggctctgctg cagcaccgac tgctggtctt cacttcacca
    63061 aagaactgct ggcagaaatc caagctaagg gtgtccatct agtctatctg actctccatg
    63121 tcggactcgg aacctttaga cctgtttctg tggataatct ggacgaacac gaaatgcact
    63181 cagagttcta tcaactttct gaggaagctg cggccaccct tcgctctgtc aaagaaaatg
    63241 gtggtcgtgt catcgctgtc ggaaccactt ctatccgtac cttggaaact attggttcca
    63301 agtttgatgg gcaaatccaa gcagattctg gttggaccaa tatctttatc aaacctgggt
    63361 atgagtggaa ggtcgtggat gccttctcaa ccaacttcca cctgccaaaa tcaactctgg
    63421 tcatgttggt ttctgccttt gcaggccgtg aattagtctt agatgcctac caccattcca
    63481 tccaagaaca ctaccgcttc ttcagttttg gtgacgccat gtttatttat tgagaaagaa
    63541 tttctctaaa tcttctaata ccaataaatc gctaagatat tatttcaaag aacatctaca
    63601 attgaaactc tagctagctg tagaagacgc ctagtacatt gaaattaaaa tgcaagacac
    63661 atgagtagca ccatatttgt tgctcttatc tgtcctcgca agagactatt atgagttatt
    63721 tcagaatcat tcactacttt gaccctgact ctccttagtc tcaaaatcaa agacttatac
    63781 tcttcaaaaa tctcttcaaa ccgcgtcaac gtcatcttgg attatatatg tgactgactt
    63841 cgtcagttct atctacaacc tcaaagcagt actttgagca acctgcgact agttttctag
    63901 tttgctcttt gattttcatt gagtattaaa caaaaagtga acaaagctga attctaatgt
    63961 acagaagact aggcttgttc acttttttat agtcgctata agatgacctt atctatagct
    64021 ttttatatat aattatatat tcagacatac tattatcaat tttgtcgcag ggaggaatct
    64081 gttaacgcac ccattcacca ttatcattga ctctatagcc atctatactt gtattgaccg
    64141 ctaactcacc cgatgtattt acataatacc atttaccacc aacttggaac cattgattga
    64201 ctttcataga accgttgctg ttgaggtagt accatgaacc attaacttgt acccaacctg
    64261 ttgccatgga accatcagta ttataaaaat accacatacc attttcttgt ttccagcctg
    64321 ttgttggagc aactgcttta gctggttcta ctgctacatc tgttccttgg ttagatgtaa
    64381 cagatacagg atacgaagga atagatgatt gctcaggaac aacaactttt tcaggttctc
    64441 tcgtccctct ccttatacgt ctttttacca tctctttagt aatttgacga gaagtagttt
    64501 cttcaattgt tccatcacgt tcatctacag catagattgt agtaagagta attttaccaa
    64561 tttctcctac ttcttgacct ttatcaagag ttgggtcatc gagatattct gtttcgattg
    64621 gaatttcttg gacaagaact tggggcttgg ttcctttttt aacaactctt gtttgagagt
    64681 cttctttttg acttaaagta ctctcagtta cttgtccact ctttccatct acatcataag
    64741 ttatcgttgt aactgttttc ccattctttc ctagagtaat ctcttgctcc tgtcctgcag
    64801 aaaggtcatt gtctgcttca tatttagtag taaatggaac aagaacttct tcaaccttgc
    64861 ttttagctgg aactttgata actgtatccg tggcttcttt tctatcaaca gtaacctttt
    64921 cggtaacatg accagtctct ggattaacat cgtaggtcct tgtcgtagtt acatagccat
    64981 cctctccatc aattgtaaca ggattttcac tacggtcttt tgtttcatct ttttcataac
    65041 gaattcgcgt acttgaaatt ttcttggtta ctaccttagg tttagtcgct acttttacaa
    65101 taatactccc attgtcagcg tcatcatact ctattccctc ttctttatct ctagtatcat
    65161 ctctgacata ttgaatccca tcagcagcat gaacaaaact tgtattcaga ttcctcctaa
    65221 aaataaagtt agcccgatta ccgcagaacc aaaaatcttt ccgagtttac gtaatgcata
    65281 gcgcttatta gtattagatt ttgccattac atcctacttc tagtatagca tcttttctat
    65341 caaacgttaa acagtatact ttatatatca gatagactta gaatgatata ttgattattg
    65401 aactaacact ttaactatat cgtaatcaat ctcatatata aaggattgca gacatcttat
    65461 ctaaatacat gctaatatat ttagatacaa acattccaac ttgataattt tcactcatct
    65521 ttcatcattc cttatacaac tatgcagtat aaatagaata gttttctcat cagaatgaga
    65581 ctattttaat attagataat ttgatagaaa aaaacataaa taaaattggt tgaatttaat
    65641 tccctaactc gatagaagat tctattttaa atttaacaac agctaggatt acactataaa
    65701 aagcacatta ccacctgttc gactggagaa tctagtcgat tagctccctc ttagttacaa
    65761 gcttaaagcg attttttaac taatactaaa ccagattaaa gaaggaacta gaacatctgt
    65821 cttgtactaa tcaatatgct attttaaaat tgcaaataaa cttggaatgc taattattat
    65881 atttacaata aatagttgac ttcgatagaa acagaaaata gaattcaaca ttcttcccta
    65941 cttataccat aataaataag atccgcaaga tagccttttc tctctacacc attaacaatg
    66001 gtttgtagat aggacattcc agccttttcc atgacacgac ctgaagctgg gttgagactg
    66061 gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa aacaaaagtc caagacagct
    66121 ttcaaggcct ctgtcatcat accatgtccc cagtaagcct tgcctagcac atagccgatt
    66181 tcacagctta aatcagcctc gtctatctta acgatgctga tatctcctat cacttgctct
    66241 gggttttctt ttagacaaat ggcccattta taatagttga gattagtata ggaagcaacc
    66301 caattgcgaa tcgagtttcg agtgatttcg acatcaggat ggggatccca ggtaacatag
    66361 gtcagattct cagcggatga agcccaattt tgaaacatgg cttctgcatc actctccaca
    66421 aatcttctta aaatcaaacg ttctgtctgt aatatttgcg taccgataga tttcatgatg
    66481 ctacctcact tccttatttc tatgctcgta gtaaaaagac tcaactcagt aacagctaga
    66541 aaacgagttt gtcttctaat ttcttgacgc agttgctgca tggtttgaaa tgcgctctag
    66601 caatcttttt caaacctagt catcgttgca ggggtaagac gatgaaatcg aactcttcga
    66661 gttaccgaat ctgcctcatt ttcttatttc taaactcggg gttcaagatc ccccggacct
    66721 ttttactccc aaaagtcatc aaatacggtg atgggtaagt ggcgtttgtg ttggcctttg
    66781 tgccaccagt tttcaatggt cgcttgagct tctgggctga ttgttttgcc ttctaggtaa
    66841 tcgtcaatct ctgcataggt gactccaagt gcgacttcgt cagctaggcc tggtttgtct
    66901 tcttctaggt ctgccgttgg gattttttca taaagggctg gctctgcgcc aagtttctgc
    66961 aagagttgtt ttccttggcg tttattgagg cggtaaagag ggagaatatc cgcaccgccg
    67021 tcaccaaact tggtaaagaa acctgtgata ttttccgcgg cgtggtctgt tccaatgacc
    67081 gctccgctat gggaaccagc aagggcatac tgagcaatca tacggcaacg tgccttgata
    67141 ttccccttgt tgaagtctga aacaggacta cctgtcgctt caactgcagc tgtcatggca
    67201 tcagctgatt ccttgatatt cacaaccaag ctgacatctg gctggatgaa ggctagggct
    67261 ttttgagcat ctgcttcatc agcttgcact ccgtatggca ggcggacagc gataaatttg
    67321 tagctatcgt ctcccgtttc agctcgcagt tcttccatag ctaattgcgc caaacgtcct
    67381 gccaaggttg aatcttgtcc cccagaaatc cctagtacaa aggtttttag gaagggatgt
    67441 tttttcagat atctttttaa gaaatcaata gaacgacgga tttcttcctg ggcatcaatc
    67501 actggtttga cacccagctc ttggataatc gtttcttgca aactcattct tcttctcctt
    67561 caccaagggc ttccttgcgc atcttatcaa tcaagtccat cttatcttgc catacatcac
    67621 gcgccaaatc cactggatag tgctgcggat tgagcacacg cttatactca tcccacaact
    67681 tgtcaaattc cttacgggca taatcctgaa tgtcagtcaa actaggcaag ttgtaaacta
    67741 atataccttc tttgaagata tccaccaaga gaggaacggc atcaaaatta cgaaccgtct
    67801 tcttgatgta tgtataggtc ggatggaaca tcttgatttc tgtcatgtcg ctaatatcca
    67861 caccatcata agtgatgtag tcaccttctg acttgccttt ttcacgactg gtaatgcgcc
    67921 acacctgctt cttacctggc gtcgacactt tttccgcatt attagacagc ttaatcgtat
    67981 tgcgcatctg accagtttca tcttcgattg caacaatctt gtaaaccgcc ccaagagctg
    68041 gctggtcata ggctgtaatc agcttggtac ccacgcccca gacatcaatc ttggcctttt
    68101 gcatcttgag gttgaggata gtattttcgt ccaaatcatt agaagcataa atcttagcct
    68161 ctgtaaatcc agcctcgtcc agttgctgac ggactttctt agaaatgtag gcaatatccc
    68221 cagagtcaat ccgcacaccc ataaagttaa tctgatcacc cagctcacgc gccacctgaa
    68281 tggcagctgg tacaccgatg cgaagggtgt cataggtatc cacaagaaag acacaatttt
    68341 tgtgggtcgc agcgtaagcc ttgaaagctt catagtcatt gccataaacc tgtaccaagg
    68401 catgggcatg ggttcccaaa acaggaatgt caaagagctt acccgcacgc acgttgctgg
    68461 ttccattggc gccaccaatc acagctgcgc gtgttcccca gatggccgca tccatttctt
    68521 gagcccgacg tgtcccaaac tccatcaagg gttcatcttc gataaccgaa cgaatacgag
    68581 ctgccttcgt cgccaccaag gtctggtagt tgacgatgtt caaaagagcc gtttcgacca
    68641 actgacattg ggctagaggt ccttccacct gcacaatcgg ttcattagca aaaaccaaat
    68701 ccccttcttg ggcagaacga acggtcaact ccaacttgaa attgcgaagg taatccaaga
    68761 acgccccatg ataaccaagc gactccaaat aggctatatc actatctgaa aaacgcaagt
    68821 cttcaagata gttcacaatt ctttccaaac ctgcaaaaac cgcatagccg ttcttaaaag
    68881 gctgttggcg gaaatacacc tcaaagaccg ccttcttatt gtgaatccct tggtcaaagt
    68941 aaacctgcat catgttgatc tggtacaagt ccgtgtgcaa tgtcaaacta tcatctggat
    69001 acatactttt cctacttcct tagctagaaa cccatgaaaa ttttcaagaa ctttcatgta
    69061 ttccaataaa ttagtactat tatatcacat tttagctgga ttgagaaaag agtaacaagc
    69121 tattctccac tctccaattc atccatatct tgttcaaatt ttttctgagc ccattcgcca
    69181 tagctcttaa gaccaagatt gccaataaag acccacggaa ggtaaatgac ataagtaatg
    69241 acccaagcag acaggtattt aaaattcaaa ggattgtgct gataaatttc tatgttgaat
    69301 tgataattct gcaacatcaa aagagccgta atagccaagg ttaggaaaaa acaacccaaa
    69361 atcgtaaaat gaaaacgact atagtaggtc actcccagat aacgggcacg attgaaaaag
    69421 taaaatgtcc ctatgatgat aacgattagc agcatattag aattaaaaag gcttggtgct
    69481 aatactgaaa tgatataaga taggagcgac aaagcaatgc agatatagaa actttcagag
    69541 cccgctttat tgaacagttg ttcttctctt tcgtctagta attgataata ataaaatcta
    69601 tttttcatct tcttcctccc aaaatagttg gtctagggtt ttccctaaac atctgcaaat
    69661 agactggcag agcgagagac tgggattgta ttttcccgcc tctatcaaac caatagtctg
    69721 gcgtgtcacc ccgacagcct ctgccagttg accttgtgtt aaatcacgct ctacccgagc
    69781 taattttaat tttaaatttt tagccacctt cgtcctcctt atagttttaa tactcatcta
    69841 ctcttaaaaa atccaaaacc aacacaagct atcagctatt tattataacc ccattaattt
    69901 gcactccagt attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc
    69961 tagtttactc ttttattttt atttagtatt agctttagta ggatctttta aacgagtttt
    70021 tattgcttat atttcttgtt tagtttagtt ggtttcatat cactattata taatgctttt
    70081 ggaaatgagc ctagtataag tcaaaaacgt gttgaatagt gaaagcagga gcataccaag
    70141 atgactgatt ttttactgta ttttaggtat gcaaaataat actaaatgaa actaaaatga
    70201 atacttcttg cttttcttga gagtgaaaaa gtacaataaa atgattgtag tgattagcac
    70261 aagatactga ctaatagaca tcgtatttga agccacaaat acaggtaaag aataaaaagg
    70321 aagaagttca attgctttga taaacaaatc attactagta ttcatcatca tcgtatttaa
    70381 tatattaggg ataaagagta gtaaagctac taaaatacca aataccaagc cacttttcaa
    70441 tttgtataaa tagaaaatgt aagataatag aaaataaaac aggactaaca aaattgtatt
    70501 gactacaata gctactataa aatctaatcc taaatcacct ggaataccca atttacttac
    70561 tatgactagt aacacaatgc cattcaaagc ataaataatg gaaactgaga tggcatatag
    70621 aaaattagac aagacgtaaa tcatccgatt cttctgttga ttataaaaca aacttaccgt
    70681 attgtgggaa aaatctctac taatgactcg attagcatgt ataacagcca ttaacatacc
    70741 gagcatagca taaaagtttg aaatatgctt aataccaagc gatgtccctt gagtctttag
    70801 aataaagaat gtaagcaata tcggcggtat aaacgagata agcaaactga gatatattac
    70861 gcctgatgaa tataaatttc ttatattttc cttaagaaaa ttaaatttat ttaatttcat
    70921 gattataacc ttcctttatt ttgaacgatt tagataaata tctttaagcg tctctttttt
    70981 agtttcaaaa tcaactactt taatagagtt ttcgttaaaa aatttaaaaa gctcactact
    71041 ttgaatattc ccagacatag taatgctcag tccctcttcc tgaacaatat ccccaaattc
    71101 ttgtttggta atgaaaatgt ctctatctgt agctgatgaa aaagctatct caaacaagaa
    71161 attatgacta tcttttccta ctttttgaaa tgtcaaaagc ccgttctcca agaaaagaac
    71221 cctctcacaa atttcttcaa tatcttctaa tttatgactc gatattaaaa ttcccacatt
    71281 ttcatgtaaa gctaaatttt ttagaaccga taaaactatt tgtgatgatt caatatctaa
    71341 accattagtc ggttcatcta aaatcaatat atcaggttcc gtaacgagag ttagaagcaa
    71401 agctaatttt tgttttgtac ccaaagaata ggtctttact tttttattaa tagactgagt
    71461 caaatctaac tcttggatca aacttctaaa tatttcttga ttgtagtcaa caccatataa
    71521 atttgacaaa tattttaaat tctctaaacc tgttttagat aaaaataatt ttggttcttc
    71581 gattaaatac ccaacattat cactgcttat aatattacct gaagtcggtt gattattctg
    71641 aacaagaatt ttcatcaacg tactcttacc aactccattt ctccctgcta gaccaacaat
    71701 ttcacccttg ttaagtgcaa aatttatatc tttgagaatg attgaatgac cataatgctt
    71761 acttacattt ataacttaca ttttttattc ctccattaat attcatggtt tgctctttga
    71821 ttcttattga gtttaaaaag ttgcgcctct ttttaacaac attatatcat atatctaact
    71881 taatgcaata tataaatgtc attttgtaaa attttattaa caaaaaactc tctacaacaa
    71941 aataatagag agttttctgc ttattaattt ttttcaaaat atctaagaca tcacttcttt
    72001 gtttaatttg ataggctttg atacctaagc tccgacttta tcacttaaaa aataaaaaag
    72061 gacagctaat ctcttgcgca tcaagggatt tcgccattct ttaatctcgt ttaagtgttg
    72121 tatatggagc tttgcataat tttttaaaac taaacaacta cattaagcac gaactgtgac
    72181 gctggttcca tcttccttat aaagattgat gagtccttct tttaatgcac gaaccatgtc
    72241 tccagcttga acaggttgag gcaccttaat agtcaatagt tccattggat ttggagcgcg
    72301 gtcgatttta ttgcctttgg catcatgcaa atcttcaata taggtttcaa aatgacggaa
    72361 acctggacca taaaactcaa cttggtcccc ttcgttaatg acgtttcgtt gacgaatagt
    72421 tgctgtttgt gccgcatcat cataagaaac cacttcagcg acaaacttgt actcagggat
    72481 tttacgacga gcaccaaaca actgctcatt ttcagatggt gtaccatagt aaaatcctgt
    72541 agccagttca cgttgggcaa ccttccacat ctcgtccacc aagtcttgtt tgatagcttc
    72601 aaacttttca ggactttcaa gataggcatc cacagccgcc ttgtagcagt tggttactgt
    72661 taatacatag tgaatagact ccatacgtcc ttcgattttt agactgtcca caccattttc
    72721 aatcatatct gagatatggt caatcataga catatcaaca gctgacattg aaaattcttc
    72781 tggaatctca ccctgcaaac tcttacgttc tttcccaaat ggcatatcgt aaaggtcgta
    72841 cttccaacgg catgactgag aacatccacc acggttggca tcacgcatac tctagacgga
    72901 ttgttttgac aattctaacc ttttagactt tgcataataa ctgttaaaca gtcgaaaatt
    72961 accccagttt taacaagtag tcaaaatacc agataaagta aaaaggggct aggaaaaaag
    73021 tctttaaaat cttaaaaacg catagtatca ggtattgaac aatcttgata ttatgcgttt
    73081 tattgtggga agatttactt cattttctct tggaattgag ttttctccta cttcaaaact
    73141 agatgatttg ctatttaaaa tagcgttcct tatgattttg gcaacctgga ttaaagcgag
    73201 aaaaacaaaa gaggcaactt aagctttctt tatattgctt atatgttaat agttttagac
    73261 aaacaccaca taaaataggc ttatcctgta tcaaagataa gggataaggc tcaaaagggt
    73321 gattttctaa tgaatcatga caccgataac aagcataata ctttttacaa tcatagcatt
    73381 gtaaagcaat aatatccagc ttgctatggt aatgaatgca tcttgtttgc ttatccacta
    73441 agaaaccctg tgcctctatc atttcctttt cctttcttaa gctcgaactg tgacgctggt
    73501 tccatcttcc ttataaaaat tgatgagtcc ttcttttaat gcacgaacca tgtctcctga
    73561 ttgaacgggt tgtgggactt taatagtcaa tagttccatt ggatttggag cgcggtcgat
    73621 tttattgcct ttggcatcat gcaaatcttc aatataggtt tcaaaatgac ggaaacctgg
    73681 accataaaac tcaacttggt ccccttcgtt aatgacgttt cgttgacgaa tggttgctgt
    73741 ttgtaccgca tcatcataag aaaccacttc agcgacaaac ttgtactcag gaattttacg
    73801 gcgagcacca aacaactgct cattttcaga tggtataccg tagtagaaac ctgttgccaa
    73861 ttcacgttgg gcaaccttcc acatctcgtc caccaagtct tgtttgatag cttcaaactt
    73921 ttcaggactt tcaagatagg catccacagc cgccttgtag cagttggtta ctgttgatac
    73981 gtagtgaata gacttcatac gtccttcgat ttttagactg tccacaccat tttcaatcat
    74041 atctggaatg tggtcaatca tagacatgtc aacggctgac attgaaaatt cttctggaat
    74101 ctcaccctgc aaactcttac gttctttccc aaatggcata tcgtaaaggt cgtatttcca
    74161 acggcatgac tgagaacatc caccacggtt ggcatcacgc atactcatgt ggtttgaaag
    74221 agtacaacgt ccagagtatg aaatacacat agctccatgg acaaaggctt caatttcaac
    74281 atctgtacgt ttgcggatct cagctaattc ttccattgaa acctcacgcg ctaaaacgac
    74341 acgagtcaag cctagctctt tccagaactc aagggtttca tagttagtgg cactggcttg
    74401 ggtagaaagg tggatttcaa ggcctggtgc ttcagtcgct gcaatcataa tcaaggctgg
    74461 gtcagatacg ataactgctg caatcccgat atcacgcagt ttacggaacc actcaccagc
    74521 accagcttca tttccttcgt gcataaccat attagccgct acatagacct tggcaccata
    74581 cttggccgca aactgcacgc cttcttccat ctgttcgaaa gtaaagtttc ccgcacggct
    74641 acgaagacca taggcctgac caccgataaa aacagcatct gctccatact gaacagctac
    74701 ctttagcttc tctaaagtcc ctgcaggtga taaaacctca ggacgtttta atgtttttgt
    74761 catgatttct cctatttgca atataaaagt ttgacatttt tccttctcat tttatagtaa
    74821 ataaaggata aaatcaagcc tagacggatt gttttgacaa ttctaatctt ttagactttg
    74881 cataataact gttaaacagt cgaaaattat cccagtttta acaagtagtc aaaaagtcta
    74941 gaaaagtaaa aaccagtatc ccaagatact gactcgtaaa aatacataaa ttagtcctta
    75001 gatgactact cccactctgt tgctcctata atggaaaagg attgatacag tctagaatat
    75061 cgctttttta tttattattc tgatataaaa ctgttagaat tgattttttg ttttataccc
    75121 aaatatgaat agagacatag ctaataagtt gaataacata tttggaaaaa tgagaaatag
    75181 caatattact agaattttta gaaacaatca atattta
//
LOCUS       DAVMBH010000005        74615 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVMBH010000005 DAVMBH010000000
VERSION     DAVMBH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.005"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            101..2230
                     /locus_tag="VYP30_000367"
     CDS             101..2230
                     /locus_tag="VYP30_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1807421.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPDRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            2217..2666
                     /locus_tag="VYP30_000368"
     CDS             2217..2666
                     /locus_tag="VYP30_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1807422.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            2725..2997
                     /locus_tag="VYP30_000369"
     CDS             2725..2997
                     /locus_tag="VYP30_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1807423.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(3351..3542)
                     /locus_tag="VYP30_000370"
     CDS             complement(3351..3542)
                     /locus_tag="VYP30_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807424.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            3969..4727
                     /locus_tag="VYP30_000371"
     CDS             3969..4727
                     /locus_tag="VYP30_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807425.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4729..6717
                     /locus_tag="VYP30_000372"
     CDS             4729..6717
                     /locus_tag="VYP30_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807426.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(6760..7404)
                     /locus_tag="VYP30_000373"
     CDS             complement(6760..7404)
                     /locus_tag="VYP30_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1807427.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(7430..8305)
                     /locus_tag="VYP30_000374"
     CDS             complement(7430..8305)
                     /locus_tag="VYP30_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1807428.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNRENASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPDKKQASTNFKPAGQSIEQRSEAINLRLENGYYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHP
                     YASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            9012..10487
                     /locus_tag="VYP30_000375"
     CDS             9012..10487
                     /locus_tag="VYP30_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1807429.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(10453..11168)
                     /locus_tag="VYP30_000376"
                     /pseudo
     CDS             complement(10453..11168)
                     /locus_tag="VYP30_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            11255..11392
                     /locus_tag="VYP30_000377"
     CDS             11255..11392
                     /locus_tag="VYP30_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807430.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            11423..12283
                     /gene="speE"
                     /locus_tag="VYP30_000378"
     CDS             11423..12283
                     /gene="speE"
                     /locus_tag="VYP30_000378"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1807431.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            12280..13539
                     /locus_tag="VYP30_000379"
     CDS             12280..13539
                     /locus_tag="VYP30_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1807432.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLLDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            13539..14666
                     /gene="nspC"
                     /locus_tag="VYP30_000380"
     CDS             13539..14666
                     /gene="nspC"
                     /locus_tag="VYP30_000380"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1807433.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            14663..15748
                     /gene="aguA"
                     /locus_tag="VYP30_000381"
     CDS             14663..15748
                     /gene="aguA"
                     /locus_tag="VYP30_000381"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1807434.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPVVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVAIDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            15758..16633
                     /gene="aguB"
                     /locus_tag="VYP30_000382"
     CDS             15758..16633
                     /gene="aguB"
                     /locus_tag="VYP30_000382"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1807435.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(16814..17623)
                     /locus_tag="VYP30_000383"
     CDS             complement(16814..17623)
                     /locus_tag="VYP30_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1807436.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            17895..18116
                     /locus_tag="VYP30_000384"
     CDS             17895..18116
                     /locus_tag="VYP30_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1807437.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            18170..18841
                     /locus_tag="VYP30_000385"
     CDS             18170..18841
                     /locus_tag="VYP30_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807438.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(18893..19090)
                     /locus_tag="VYP30_000386"
     CDS             complement(18893..19090)
                     /locus_tag="VYP30_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807439.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            19083..19991
                     /locus_tag="VYP30_000387"
     CDS             19083..19991
                     /locus_tag="VYP30_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1807440.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            19988..20449
                     /locus_tag="VYP30_000388"
     CDS             19988..20449
                     /locus_tag="VYP30_000388"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1807441.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            20439..21326
                     /locus_tag="VYP30_000389"
     CDS             20439..21326
                     /locus_tag="VYP30_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1807442.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            21329..23224
                     /gene="cbpE"
                     /locus_tag="VYP30_000390"
                     /gene_synonym="pce"
     CDS             21329..23224
                     /gene="cbpE"
                     /locus_tag="VYP30_000390"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1807443.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHLDTKNSNTKNFIKNLSPEIIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQHINAASKDYDATVFDIRQDGLVNISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     RWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQY
                     KGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWL
                     KKANDWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVP
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            23304..24434
                     /locus_tag="VYP30_000391"
     CDS             23304..24434
                     /locus_tag="VYP30_000391"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1807444.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            24444..25706
                     /locus_tag="VYP30_000392"
     CDS             24444..25706
                     /locus_tag="VYP30_000392"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1807445.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAIA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            25710..26507
                     /gene="proC"
                     /locus_tag="VYP30_000393"
     CDS             25710..26507
                     /gene="proC"
                     /locus_tag="VYP30_000393"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1807446.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            26727..27365
                     /locus_tag="VYP30_000394"
     CDS             26727..27365
                     /locus_tag="VYP30_000394"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1807447.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            27362..28252
                     /locus_tag="VYP30_000395"
     CDS             27362..28252
                     /locus_tag="VYP30_000395"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1807448.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            28292..28609
                     /gene="yabA"
                     /locus_tag="VYP30_000396"
     CDS             28292..28609
                     /gene="yabA"
                     /locus_tag="VYP30_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1807449.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            28612..29481
                     /gene="rsmI"
                     /locus_tag="VYP30_000397"
     CDS             28612..29481
                     /gene="rsmI"
                     /locus_tag="VYP30_000397"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1807450.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQILKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            29708..30226
                     /locus_tag="VYP30_000398"
     CDS             29708..30226
                     /locus_tag="VYP30_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1807451.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            30335..30982
                     /locus_tag="VYP30_000399"
     CDS             30335..30982
                     /locus_tag="VYP30_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1807452.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(30971..31775)
                     /locus_tag="VYP30_000400"
     CDS             complement(join(30971..31405,31407..31775))
                     /locus_tag="VYP30_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1807453.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLTVLKTAYQLKHAKGG
                     RKPKLSLEDLLMTTLQYMREYRTYEEIAADFGIHESNLIHRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANYYGKKKCHAMKAQTIVTSQGRIVSLDITVNY
                     CYDMKLFKMSRRNIGQAGKILADSGYQGLTKIYPQAQTPRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            31770..32024
                     /locus_tag="VYP30_000401"
     CDS             31770..32024
                     /locus_tag="VYP30_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1807454.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            32269..33603
                     /gene="trmFO"
                     /locus_tag="VYP30_000402"
     CDS             32269..33603
                     /gene="trmFO"
                     /locus_tag="VYP30_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1807455.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            33687..34424
                     /locus_tag="VYP30_000403"
     CDS             33687..34424
                     /locus_tag="VYP30_000403"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1807456.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            34433..34990
                     /gene="frr"
                     /locus_tag="VYP30_000404"
     CDS             34433..34990
                     /gene="frr"
                     /locus_tag="VYP30_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1807457.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASELGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            35050..35904
                     /gene="cvfB"
                     /locus_tag="VYP30_000405"
     CDS             35050..35904
                     /gene="cvfB"
                     /locus_tag="VYP30_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1807458.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            35913..36128
                     /locus_tag="VYP30_000406"
     CDS             35913..36128
                     /locus_tag="VYP30_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1807459.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            36214..37182
                     /locus_tag="VYP30_000407"
     CDS             36214..37182
                     /locus_tag="VYP30_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1807460.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(37160..37339)
                     /locus_tag="VYP30_000408"
     CDS             complement(37160..37339)
                     /locus_tag="VYP30_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807461.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            37375..37875
                     /locus_tag="VYP30_000409"
     CDS             37375..37875
                     /locus_tag="VYP30_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807462.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            37878..38138
                     /locus_tag="VYP30_000410"
                     /pseudo
     CDS             37878..38138
                     /locus_tag="VYP30_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(38505..39616)
                     /gene="ald"
                     /locus_tag="VYP30_000411"
                     /pseudo
     CDS             complement(38505..39616)
                     /gene="ald"
                     /locus_tag="VYP30_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            39793..40362
                     /locus_tag="VYP30_000412"
     CDS             39793..40362
                     /locus_tag="VYP30_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807463.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            40430..41080
                     /locus_tag="VYP30_000413"
     CDS             40430..41080
                     /locus_tag="VYP30_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV1807464.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD"
     gene            41064..43304
                     /locus_tag="VYP30_000414"
     CDS             41064..43304
                     /locus_tag="VYP30_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1807465.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            43493..43681
                     /locus_tag="VYP30_000415"
     CDS             43493..43681
                     /locus_tag="VYP30_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807466.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            43714..44301
                     /locus_tag="VYP30_000416"
     CDS             43714..44301
                     /locus_tag="VYP30_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807467.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            44305..45486
                     /locus_tag="VYP30_000417"
     CDS             44305..45486
                     /locus_tag="VYP30_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807468.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEAKLSQMSDTSSEEYQFAKSNLELQKNLLKRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    45646..45777
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            45793..46323
                     /gene="infC"
                     /locus_tag="VYP30_000418"
     CDS             45793..46323
                     /gene="infC"
                     /locus_tag="VYP30_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1807469.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            46356..46556
                     /gene="rpmI"
                     /locus_tag="VYP30_000419"
     CDS             46356..46556
                     /gene="rpmI"
                     /locus_tag="VYP30_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1807470.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            46608..46967
                     /gene="rplT"
                     /locus_tag="VYP30_000420"
     CDS             46608..46967
                     /gene="rplT"
                     /locus_tag="VYP30_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1807471.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            47025..47405
                     /locus_tag="VYP30_000421"
     CDS             47025..47405
                     /locus_tag="VYP30_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1807472.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            47655..48455
                     /locus_tag="VYP30_000422"
     CDS             47655..48455
                     /locus_tag="VYP30_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1807473.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHGRGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            48466..49404
                     /locus_tag="VYP30_000423"
     CDS             48466..49404
                     /locus_tag="VYP30_000423"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1807474.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPVIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            49446..51479
                     /locus_tag="VYP30_000424"
     CDS             49446..51479
                     /locus_tag="VYP30_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEV1807475.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKEKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     YSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNKNAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(51540..53195)
                     /gene="pavA"
                     /locus_tag="VYP30_000425"
     CDS             complement(51540..53195)
                     /gene="pavA"
                     /locus_tag="VYP30_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1807476.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQENKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            53300..53797
                     /gene="ybeY"
                     /locus_tag="VYP30_000426"
     CDS             53300..53797
                     /gene="ybeY"
                     /locus_tag="VYP30_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1807477.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISSDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            53778..54173
                     /locus_tag="VYP30_000427"
     CDS             53778..54173
                     /locus_tag="VYP30_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1807478.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEILNSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            54190..55089
                     /gene="era"
                     /locus_tag="VYP30_000428"
     CDS             54190..55089
                     /gene="era"
                     /locus_tag="VYP30_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1807479.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMLREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            55138..55962
                     /gene="mutM"
                     /locus_tag="VYP30_000429"
     CDS             55138..55962
                     /gene="mutM"
                     /locus_tag="VYP30_000429"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1807480.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQIHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            55962..56567
                     /locus_tag="VYP30_000430"
     CDS             55962..56567
                     /locus_tag="VYP30_000430"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1807481.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            56554..57753
                     /locus_tag="VYP30_000431"
     CDS             56554..57753
                     /locus_tag="VYP30_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV1807482.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            57753..57902
                     /gene="rpmG"
                     /locus_tag="VYP30_000432"
     CDS             57753..57902
                     /gene="rpmG"
                     /locus_tag="VYP30_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1807483.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            57942..58175
                     /gene="secG"
                     /locus_tag="VYP30_000433"
     CDS             57942..58175
                     /gene="secG"
                     /locus_tag="VYP30_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1807484.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            58277..60631
                     /gene="rnr"
                     /locus_tag="VYP30_000434"
     CDS             58277..60631
                     /gene="rnr"
                     /locus_tag="VYP30_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1807485.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTIIQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            60594..61061
                     /gene="smpB"
                     /locus_tag="VYP30_000435"
     CDS             60594..61061
                     /gene="smpB"
                     /locus_tag="VYP30_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1807486.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            61077..61937
                     /gene="tehB"
                     /locus_tag="VYP30_000436"
     CDS             61077..61937
                     /gene="tehB"
                     /locus_tag="VYP30_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1807487.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            62010..62963
                     /gene="coiA"
                     /locus_tag="VYP30_000437"
     CDS             62010..62963
                     /gene="coiA"
                     /locus_tag="VYP30_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1807488.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            62982..64784
                     /gene="pepF"
                     /locus_tag="VYP30_000438"
     CDS             62982..64784
                     /gene="pepF"
                     /locus_tag="VYP30_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1807489.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYVDLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            64786..65499
                     /locus_tag="VYP30_000439"
     CDS             64786..65499
                     /locus_tag="VYP30_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1807490.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            65566..66507
                     /gene="prsA"
                     /locus_tag="VYP30_000440"
     CDS             65566..66507
                     /gene="prsA"
                     /locus_tag="VYP30_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1807491.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(66623..66964)
                     /locus_tag="VYP30_000441"
                     /pseudo
     CDS             complement(66623..66964)
                     /locus_tag="VYP30_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            67345..70040
                     /locus_tag="VYP30_000442"
                     /pseudo
     CDS             67345..70040
                     /locus_tag="VYP30_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            70341..71180
                     /locus_tag="VYP30_000443"
     CDS             70341..71180
                     /locus_tag="VYP30_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1807492.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            71198..73036
                     /locus_tag="VYP30_000444"
     CDS             71198..73036
                     /locus_tag="VYP30_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1807493.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            73049..74464
                     /locus_tag="VYP30_000445"
     CDS             73049..74464
                     /locus_tag="VYP30_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1807494.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT        22553 a        13417 c        16567 g        22078 t
ORIGIN      
        1 ttttgagcag cctgcggcta gcttcctagt ttgctttttg attttcattg agtatgaaaa
       61 ggattggaga aagccttcca gcttgtggta taatagattt atggataaaa aatatgaaaa
      121 aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa gtttgacagc
      181 tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg gtagtctgga
      241 tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc tcaatgaccg
      301 taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg aattggaaga
      361 agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc cttataagga
      421 aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc ttgctcgctt
      481 gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct gtgaaggatt
      541 tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag ccttatcgga
      601 agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta aactcacttc
      661 tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt atgatttttc
      721 agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg gggagaaact
      781 tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct tctttgctac
      841 tcgtttcaag gtgaaaaatg cttatattga tgaagttgtt cagcaatccg ttaagaaaaa
      901 ggtcttgcct gctattgagc gtcgtattcg gacagaatta actgagaaag ctgaagaggg
      961 agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc cactgaaagg
     1021 gcgcgtggtt cttggatttg acccagcctt tcgtacaggt gccaagttag ctgtcgtgga
     1081 tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag catcagctcg
     1141 tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg gtgtagagat
     1201 tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag cggaagttct
     1261 gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt ctgtctattc
     1321 tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac gctctgccat
     1381 ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg atcctaagtc
     1441 aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactatctg agagtctgga
     1501 ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag ctagcccagc
     1561 tcttctttca cacgtagctg gactcaacaa aactatctct gaaaatattg tcaaataccg
     1621 cgaggaagaa ggaaaaatca cttcacgcgc ccaaatcaag aaagttcctc gtctgggagc
     1681 caaggccttt gagcaggctg ctggtttcct tcgtatccct gaaagtagca atatccttga
     1741 taatacagga gttcacccag agaattacac tgccgttaag gaactcttca aacgtttaga
     1801 tattaaagac ctaaacgaag aagcccaaag caaactcaag tccctttcag tcaaggaaat
     1861 ggctcaagag ctagacctcg gtccagaaac ccttaaagat atcattgcag atcttctcaa
     1921 accagatcga gatttccgtg attcctttga cgcacctgtg cttcgccaag atgtcctaga
     1981 tatcaaagac ctagtggtag gtcagaagct agaaggtgtt gtgcgtaacg ttgttgactt
     2041 cggtgccttc gttgatatcg ggattcacga ggacggcttg attcatattt ctcatatgag
     2101 tcgcaagttt atcaaacacc ctagtcaagt ggtggcagtt ggagatttgg tgaccgtttg
     2161 ggtcaagaaa attgatactg aacgtgaaaa agttaatctg tcgctcctcg ctccaaatga
     2221 aactgactga ttatgtcaag caggtttcac tagaagactt cggcagacct tttatccatc
     2281 atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc aaagatgggc
     2341 atctggattt taatcccaag gtttatcaga aactgggtat ggaggttttt aggaaaattg
     2401 tccgacatga actctgtcat tatcaccttt atttccaagg gaagggctat caacacaagg
     2461 atcgggattt taaggaactt ttgaaagcag tggatggatt acggtttgta ccatccttgc
     2521 ccaatagtaa ctctaaacca ctcaagcttt atcgttgtca atcctgccag caaaggtatc
     2581 agcgcaagcg taggattgat accaaacgct atcgctgtgg actttgtcga ggtaaattgc
     2641 ttctgataaa tcagcctgag gactgatgaa agccgagcct ccccgtgata tactatgtct
     2701 aacctagcag aaagaggaaa tatcatgaac agtaaatttt ataaaatgag acgcaatcgc
     2761 atgatttcag gagttctggc aggtctgtca gacaagtgga attttgatgt taccctagtt
     2821 cgtttcttgt ttgctatttt tacagttgca aactttggac ttggcgtgat tatctatatc
     2881 atcctagctt ctatcatgcc taccaaggaa gaaatcgaag cagaaatgta cggaacaggc
     2941 ccacgtaaac gcaaagaagc ccaagccatt gacgacaatg aaggctggtt ttggtgaggt
     3001 tctacagaag atttggaata agcaaaaagc tttaaatcaa tagtctaaac tgcttgattt
     3061 aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa gccagccaca
     3121 ggctgtaatt tagtcggcaa tgtgaagttg acatagtttg cactttgatt tttgaatagt
     3181 attaataata tttcgccagc ttcatccaca aactatagtg gattggaact agaataggac
     3241 acctctactt ctaaaacatt gttagaaatc gatttgacta tcctgatcga tttgtcctgt
     3301 tcttatttca ttttattata aaagcagtaa tttaaactca gttttttaat ctatttttgc
     3361 tgctgagaca atacattttt ggaaaaatgg tggatgctga taacaactga taaccagcaa
     3421 ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc aactaagagc
     3481 tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc tttgtgtttc
     3541 attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa attgaatggt
     3601 atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttc aaagtaagcc
     3661 ttttcacact tatattttac aactttaaaa ataggaaatc aaatcatttt ctaagtaatt
     3721 ttgcttatat ttcacccaat cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta
     3781 ggttatggca agcggtcttt ttttgatgta aactagactc ataaagaaca aaggagtaac
     3841 atcatgaaac aaatcttaca taagaaaact agaaaaccaa gtcacaaaga aattgagcgc
     3901 gttcagctgg gatgcactat gatgcaagct acatttcatt tgatgggata ttaagaaagg
     3961 agattctcat gacactttta gatgtaaaac acgttcaaaa aatttataaa acacgttttc
     4021 agggcaacca agtagaagcc ctcaaggata ttcactttac cgtcgaaaag ggtgactacg
     4081 ttgccatcat gggtgagtct ggttctggta aatcaactct tctcaatatt ctagctatgc
     4141 tggataaacc aagtcgtggt caggtttact tgaatggaac tgacaccgca accattaaaa
     4201 attcacaggc ctctagcttc cgtcgtgaaa agttgggctt tgtcttccaa gactttaact
     4261 tgctagatac tctatctgta aaggacaata tcttgcttcc gcttgtcttg tcaagaagac
     4321 ctattacaga gatgatgaag aaattggtgg tgacagctga gaatctggga ataaaccaat
     4381 tacaagagaa gtacccttac gagatttctg gtggtcagaa acagcgtgta gcagtagccc
     4441 gcgccatcat cacagaacct gaaattctcc ttgcggacga accgacagga gctcttgact
     4501 ccaagtcatc tgcagcctta cttgatgtct ttgatgaaat caatgagcgc ggccaaacca
     4561 ttctcatggt aacccactca acagcagcag ctagcagagc taaacgtgta ctctttatca
     4621 aagacggcat tctttacaat caaatctacc gtggagagaa gacagaacgt cagatgttcc
     4681 aagaaatctc tgataccttg actgtcatgg caagcgaggt gaattagtat gtttcgatta
     4741 accaataagt tagcggtatc gaacttgatt aaaaaccgca aactctacta tccttttgcg
     4801 ctggctgttc tcttggcagt cactgtcacc tatctctttt actctctaac cttcaatcct
     4861 aagattgcgg aaatccgtgg aggaacaacc attcaggcta cacttggatt tggtatgttt
     4921 gtcgtcaccc ttgcgtcagc cattatcgtt ctctatgcca atagttttgt catgaagaac
     4981 cgttccaagg aactaggaat ttatggcatg ttgggcttgg agaagcgtca tcttatcagt
     5041 atgaccttta aggagttagt ggtatttggg attctaactg ttggagcggg tatcggtatt
     5101 ggagccttgt ttgacaagtt aattttcgct ttcctgctca aactaatgaa attgaaggtt
     5161 gagctggttg ctaccttcca gacgaaagtt gtcattacag tgcttgttgt cttcggtttg
     5221 attttcctag gcctcatgtt cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag
     5281 ctctctcgtg agaaagctag tggagagaaa aaaggtcgct tccttcctct ccaaaccatt
     5341 cttggttcca taagtttagg aattggctat tatcttgccc ttacggtaaa agatcctctt
     5401 acagccttaa caaccttctt catagctgtt ttactggtta tctttgggac ttatctcttg
     5461 tttaatgcag ggattaccgt tttcctccaa atcttaaaga aaaataagaa atactattac
     5521 caaccaaata acctcatatc tgtttctaac ttgattttcc gtatgaagaa aaatgcagtt
     5581 ggactagcca ccatcgctat cttgtcaaca atggttttgg taaccatgtc agcagcgaca
     5641 agcattttca attcctcaga aagctttaaa aaagttctaa atcctcatga ttttggggtt
     5701 tcagggcaaa atgttgaaaa agaagacttg gacaaactct tgagccagtt tgcaagtgac
     5761 aaaggttata agattaaaga aaaagaagta tttcgttaca cttactttgc tgttgcgaat
     5821 caagaaggaa ccaagttaac tatttttgaa aaaggacaaa accgtgtcca accaaaaaca
     5881 gttttcatgg tatttgacca aaaagattat gaaaatatga ctggtcaaaa actgtctcta
     5941 tcaggaaatg aggtcggact ctttgcaaag aatgagggag ttaaagaaca gaaagctcta
     6001 actctaaatg atcatcaatt ttctgtaaaa gaagaattta ctaaagattt tattgtcaac
     6061 catgttccaa atcagtttaa tattttgact gctgattaca attaccttgt tgtacctgat
     6121 ttacaagcct ttttggatca attcccagat tcggctatct ataatcagtt ttacggtggt
     6181 atgaatgtaa atgccagtga agcagaacaa ctcaaggtcg ctgaggagta tgaaaaatac
     6241 ttacaaaagt ttaatgctca attaaacact gaaggtaact atgtgtatgg tagcactcta
     6301 gcagatgcta gtgctcagat gagtgccctc tttggtggtg tcttctttat cggtattttc
     6361 ttatccatta tctttatggt cggaaccgtt ctggtcatct actacaaaca aatttctgaa
     6421 ggatatgaag accgtgagcg ctttattatc ttgcagaaag tcggtttaga tcaaaagcaa
     6481 atcaagcaaa ccatcaacaa acaggtttta actgtattct tccttccttt gctctttgcc
     6541 ttcctacatc tagcctttgc ctaccatatg cttagtctga ttttaaaagt gattggtgta
     6601 ctggatacga ctatgatgtt gattgtgacc ttgtctatct gcgctatctt cctcatcgcc
     6661 tatgtgctga ttttcatgat tacttcaaga agttatcgta agattgtcca aatgtaaaaa
     6721 aagatacctc gacttcaaaa tcgaggtatt tcttgttttc taaatgctga aaagttgtcc
     6781 gagcagaaag gtaactccca tagttaagag accaatagca aggttccgaa tcatagctgt
     6841 tttggttggg gcttttccaa gtctagcact tgtgtagcca gtgagaagaa gggctacacc
     6901 gacgataagg acggtagcag ggatgcggta atcacttgga aaaatggtca ctgacagcat
     6961 tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt gccaaggatt
     7021 ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga gtggattttt
     7081 aagaaagatc ttattagtca agagttgggc agaagttttg aattctccat tttggatata
     7141 agaagcatag agggattttt tggctagttc cctatcttgg tctagcaaga gtttttctcg
     7201 cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt ctccaccagc
     7261 cattgaaaag gcaccagcta agatagccgc aaaacctgat aaaaagataa tccagatatt
     7321 gctcgtggca ctggcaactc cgataaccac accagcaatg gaaataattc catcgttagc
     7381 atcaagaaca cccgcacgca ggatatttaa acgacctgca aaatttgaat caatttcgtg
     7441 atttgtttct gacgctaaat ttcaagttca agttagccat ccagaagtct tctctgggtg
     7501 acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
     7561 ctttgggagt cattttcttg gttcccttag gtaaccatct acgaatgagc ctgttgtgat
     7621 tctcattagt tcccctttcc caagaggcat aggggtgcgc ataatagatg tgctcctcag
     7681 aaaatacatc aaacaagcga ttgaattccg ttccattatc tgccgtgatg gaaagaatct
     7741 tgtgttgttt taagatgagt tttagagcct gattgaccac ctcagcactt ttatttggaa
     7801 tcaatcggat gatctgatgt ctactctttc gatccgtcaa gacaagcaag cagtagtttt
     7861 tcgctctcgt aagtagaacc gtatcaatct cataataccc attctccaag cgaagattga
     7921 tagcttcaga ccgctgttcg atggattgac cagcaggttt aaagttggtg ctagcctgtt
     7981 tcttatcagg cgaaaatttt tggttatgat agtggagaat cttttccttt agttccttgg
     8041 tcaagcttga tttcttgacc gagcgcttgc gattgttttc ataagactgt tgagcatagt
     8101 cggcagaata aacctctttg aagcgccctt ttccaagaca ttgtcggact gtcccacgct
     8161 tgatttcagt gtggatagtt tgaggagctt ttccaagtag agaggcattt tctctatttg
     8221 atttcccttc ttttttccat ctttcgatta agcgacggct atcgattgtc aaatgtttgg
     8281 cttttgtagt ataattgtct tgcatctctg tgcctttctt gtgtttgtgg ttgaacaaca
     8341 agtataacac agaggtgttt tcttatacct acaagagcta tcagctagtt gaaccatcta
     8401 atttttagga gggctgggtg gctaacttca ttatagaact ttcatttacg aacatatagt
     8461 aaaatgaaac aagaacagaa caaatcgatc aggacagtaa aatctatttc taacaatgtt
     8521 ttagaagcag aggtgtacta ttctagtttc aatctactat atttttgttt tttatcaaaa
     8581 aatactttac aagttcttaa aaacatgata tagtaataaa gcttagaaaa tgagatgatg
     8641 ttttctagca aatataaacc cgagtaaaaa atgcctacgg acaggcaggg ttgaatgccg
     8701 aagcgtggtt gaaaagccac attattgata gggttaaaag cctactttta taagttgatg
     8761 ttaggacact tgtcctaatt cataaatttt tagtgtggtg aaagcacacg tcatcttgtg
     8821 aaacgatcaa taaagtacgt aatatttgct actagagagt taggaaacat cgggaacaga
     8881 catactcaac agaaaccaaa ataaacacgt cagaagattg cagagcaggt gaaaacctgc
     8941 tcttttttca tgagtcaacc tttagttcct tagttttcat aaggtcctaa aaatattgaa
     9001 aggagtatgt tttgaaagag ttagatcaaa accaagcccc aatttatgag gccttggtga
     9061 agttacgcaa gaaaaggatt gttccctttg atgttccagg tcacaagcgt ggacggggaa
     9121 atccagaact tgtcgaactc ttaggagaaa aatgtgtagg cattgatgtc aattcgatga
     9181 aacccttgga taatttaggc catcctattt cgattattcg tgatgcagag gagctggctg
     9241 cagatgcttt tggagctagc catgcctttc taatgattgg tggaacaact tcatcggtgc
     9301 agactatgat tctggcaacc tgcaaggcag gagataagat tattctgcca cgaaatgtcc
     9361 ataaatctgc tatcaatgcg ttggttctat gtggtgccat tcccatctat atcgagatga
     9421 gtgtagatcc taagattggt atcgctttag gtcttgaaaa tgaccgagta gcacaggcca
     9481 taaaggacca tccagatgct aaggctatcc taatcaacaa tcctacttac tacggcatct
     9541 gttcagacct aaaggggttg acagaaatgg ctcatgaagc tggcatgatg gttttagtag
     9601 atgaagccca cggagcgcat ttgcatttca ctgataaact tccaatttct gctatggatg
     9661 caggggctga tatggcagca gtttccatgc ataagtctgg tgggagtttg acccaaagct
     9721 ccattttact tatcggggag cagatgaatt ctgaatacgt tcgtcagata attaacctga
     9781 cccagtctac atctgcctct tacttgttga tggctagttt ggatatttca cgtcgcaact
     9841 tggcccttcg tggtaaagag tcgtttgagg aagtcattga gctatctgag tatgcccgcc
     9901 gtgaaatcaa tgctatcggt ggctactatg cctactcaaa agagttaata gacggtgttt
     9961 cggtttgcga ttttgacgta actaagctgt cagtttacac tcagggtatt ggcttaacag
    10021 gtatcgaggt ttatgacctc ttgcgagacg aatacgacat tcagatcgag tttggtgata
    10081 tcggcaatat cttggcctat atttccatcg gcgaccgcat ccaagacatc gagcgcttgg
    10141 ttggtgctct ggctgatatt aagagactct attcaagaga tggaaaagat ttgatagcag
    10201 gagaatatat tcagcccgag ttagtgctgt ctccgcaaga agccttctat tcagaaagaa
    10261 aaagtttgac cttagatgag tctgttggac aggtctgtgg agaatttgtc atgtgctatc
    10321 ctccagggat tcctatcttg gctcctggtg aacgtattac acgagaaatt gtagactata
    10381 tccaattcgc caaggaacgt ggttgctccc tccaagggac ggaagatcca gaggtcaatc
    10441 atatcaacgt tattaagaga aagacaaact ataagaaaag tcaatagttt tatctaaact
    10501 atttcttatt tcaatttgat gatttggcga tgattttaga gcacggcaaa aagcccttga
    10561 attagaagcg gtcaatcgct taatttctat cagcttatca aatcctgcct caatcctttt
    10621 ctgaggatta gggtagcgtg tcaagagttg gtaggtatat tctgaatgct ttccaacgat
    10681 tttatccaac tcaggaaaga tgatatcaag acaacgagtg tattgtactt tccaatcaga
    10741 ctgtttttct tgagacgatg aatatgtcta gccagtattt ttaggtctac ttgccgatta
    10801 tcgtgttgaa attgttcacg attggggtca gaaagaagtt taagagcgat gccatgagcg
    10861 tctttcttat ccgttttagt cttgcgaagt gataatgatt tggcaaattc cttgatgagc
    10921 aaaggattgt aggtgtaaac tttatatcct tgttcatgca ggaagttcag tagattaaag
    10981 gcataatgtc cagtatcttc aagagcgatg agacagtctt ggttgagctg tcgaagagac
    11041 agatctaaga gttcaaaacc agctttatta tttgaaaaag tgagtggttt aagaacagtt
    11101 tttccttgaa cattcaaggc tgtaacatcg tgtttatttt tagcgatatc aatgcccaca
    11161 taaagcatgg gagtacctcc agatgtagta tttcaagtct acttggttat ccacgaactt
    11221 tttgccttgt taccttagac gagataaaac gtctatgcgt tatcaaactc attaccaatt
    11281 gaaacaaaag ctgtggttag agcctttcgg aaatcgtcaa gcgattggag gaaatgaact
    11341 aatccacagt ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcgcta
    11401 aatataatat aaggagaaat agatggattt atggttttct gaagttcata ctccagatgt
    11461 caaattgtct ctgagaacag ccaagcaact ttacgctgga aaaagtgaat ggcaggatat
    11521 cgaagtcttg gatacgccag cttttgggaa aatactgatt ttaaatggcc atgtcttgtt
    11581 ctcagatgcg gatgatttcg tctacaatga aatgaccgtt cacgttccca tggctgtcca
    11641 cccaaatcca aagaaagtat tggttattgg gggtggtgac ggcggtgttg cccaagtatt
    11701 aacactctat cctgaactgg aacaaatcga tatcgtggaa ccggatgaga tgttggtcga
    11761 ggtctgtcgt gagtatttcc cagactttgc tgcagggcta gatgatcctc gtgttaccat
    11821 ttactaccaa aatgggctac gctttttgcg aaactgcgaa gatgattacg atattatcat
    11881 caacgatgcg acagatccat ttggccatac ggaaggactc tttaccaagg aattctacgg
    11941 caatagttat cgagctctga aggaagacgg catcatgatt tatcagcatg ggagtccctt
    12001 ctttgacgag gatgagtcgg cctgccgaag catgcaccgc aaggtcaatc aatcctttcc
    12061 aatcagtcgg gtttatcagg cccatattcc aactagccca gctggctatt ggttgtttgg
    12121 atttgcatcg aaaaaatacc accctgtcaa agattttgac aaggaaggtt ggaaaaaacg
    12181 ccagcttttc acagaatact acactgcaaa cttacacgtg ggagccttta tgttgcccaa
    12241 gtatgttgag gacattttag aagaagagga aggaaaaaaa tgagtcgttt actagttatt
    12301 ggttgtgggg gcgttgccca agttgctatt tcaaagattt gtcaagatag cgaaacattt
    12361 acagagatta tgattgctag ccgtaccaag tcaaaatgtg atgacttgaa agctaaactg
    12421 gaaggcaaaa caagtacaaa gattgagaca gctgctcttg atgctgacaa ggttgaagaa
    12481 gtgattgctc tgattgaaag ctacaaacca gaagctgttt tgaatgtagc tctgccttat
    12541 caagatttaa ccattatgga tgcttgtttg gcaacaggtg ttcactatat cgatacagcc
    12601 aactacgaag cagaagacac agaagaccct gagtggcgtg ctatctacga aaaacgttgt
    12661 aaggaacttg gttttacagc ctactttgac tactcatggc agtgggctta tcaagagaaa
    12721 ttcaaagaag caggcttgac tgctcttctt ggttctggtt ttgacccagg tgtaactagt
    12781 gtcttttcag cttatgccct caaacactat tttgatgaaa tccattatat cgacatttta
    12841 gactgtaatg gcggtgacca cggttatcca tttgcaacca actttaatcc agaaattaat
    12901 ctccgtgagg tttctgcgcc gggttcttac tgggaagatg ggaaatgggt cgaagtcgaa
    12961 gctatgtcta tcaagcgtga gtatgatttc cctcaagttg gacaaaaaga tatgtatctc
    13021 cttcaccatg aagaaatcga atcattggcc aagaacattc caggtgtcaa acgcattcgt
    13081 ttctttatga cttttggtca atcttacttg acgcacatga aatgtcttga aaatgttgga
    13141 ctccttcgta cggataccat taactttaac ggccaagaaa ttgttccaat tcaatttttg
    13201 aaagccttgc ttctagatcc tgctagcctt ggcccacgta ctgtaggtaa aaccaatatt
    13261 ggatgtatct ttacaggtgt caaagacggt gtcaaaaaga ctatctatat ctacaatgtc
    13321 tgcgaccatc aggaatgtta cgcagaggtt ggttcgcaag ctatttctta tacgacagga
    13381 gttccagcca tgattgggac aaaattagtc atgaacggaa cttggaaaca agctggagtg
    13441 tataaccttg aggagttaga tccagatcca ttcatggaag ctttgaatga gtatggtttg
    13501 ccatgggttg tggttgaaaa tccacaaatg gtggactaat gaagttagaa caagtaccaa
    13561 caccagccta tgttattgac ttggccaagt tagaagctaa ttgccgcatt ctacaatatg
    13621 tacaagaaga ggccggttgc aaggtcttgc ttgcccagaa ggcatattcc ctctacaaaa
    13681 cttatccctt gattagccag tatctatcag gtacgacagc tagtggactc tatgaggcca
    13741 aattggcaag ggaagaattt cctggtgaag tccatgtatt tgcgcctgct ttcaaggatg
    13801 cagacttgga ggaattgctt gggataacag accatatcgt ctttaactca gagagacagt
    13861 tgcgtaagca tggggctcgt tgtcgagagg ctggtgtcag tgttggtttg cgcctcaacc
    13921 ctcagtgttc aactcaagga gatcacgcgc tctatgaccc ttgtgcacca ggttctcgct
    13981 ttggagttac tatagacaag attccgagtg atttgctaga tttggttgac ggacttcatt
    14041 ttcataccct ttgcgagcag ggagcagatg atttacaaac aactttgaaa gcagtagaag
    14101 aacaatttgg tccctactta catgaggtaa aatggctcaa tatgggtggt ggtcatcata
    14161 ttacaagaga aggttacgat gtggatttgc tgatttcaga aatcaagcgt atccgaaaaa
    14221 cttacaatct tgaaatctat atcgagcctg gtgaagccat tgcgcttaat gcgggttatt
    14281 tagcaactga ggtattagat attgtagaaa acggtatgga aatcttggtt ttagacgcct
    14341 ctgcgacctg ccatatgcct gatgtacttg agatgcccta tcgtccacct ttgagaaatg
    14401 gctttgaggc acaggaaaaa gcccatacct acagactttc ttctaatacc tgtctgactg
    14461 gcgatgtgat tggtgattat agttttgaaa atccagtcca aatcggagac agactttatt
    14521 ttcaagacat ggccatttat tcttttgtca aaaataatac ctttaatggt attggattgc
    14581 caagtctcta tctcatggac gaacagggag actgtagctt actcaaagct tttggctatc
    14641 aagactttaa agggagatta tcatgatgga cagtccaaaa aaattaggct atcacatgcc
    14701 agcagagtac gaaccccatc atggtaccct catgatatgg ccgactcgac caggatcatg
    14761 gccttttcaa ggaaaggctg ctaaaagagc atttactcag atcatcgaga ccatagcaga
    14821 aggggaaaga gtctatcttt tggtggagca ggcctatcta tctgaagccc aatcctatct
    14881 tggagacaag gttgtttatt tagacattcc caccaatgat gcctgggcgc gtgatactgg
    14941 cccaaccatt ctcgtcaatg ataaaggtaa gaaattagcc gtggattggg ccttcaatgc
    15001 ttggggaggc acctatgatg gtctttatca agattatgaa gaggatgacc aagtagccag
    15061 tcgttttgct gaggctttgg aaaggcctgt ctatgatgct aaaccttttg tactggaagg
    15121 aggcgcaatc catagcgatg gtcaaggaac tattctcgta actgaaagtt gcttgcttag
    15181 tcctggtcgc aatcctaact tgactaaaga ggagattgaa aacacattat tagaaagtct
    15241 tggtgctgaa aaagttattt ggcttcctta tggtatttat caggatgaaa ccaatgaaca
    15301 cgtcgataat gttgctgcct ttgttggtcc tgctgagctt gttttggctt ggacagatga
    15361 cgaaaatgat ccccagtatg ccatgtcaaa agcagatctc gaactcttag aacaggaaac
    15421 agatgcaaaa ggttgtcact tcaccattca taaattgcct atccctgtag ttcgacaagt
    15481 tgtgacagaa gaagatttgc caggctacat ctatgaagaa ggagaagaag agcgatacgc
    15541 aggtgaacga ctagcagctt cctacgtaaa cttttatatc gccaacaagg ctgtcttggt
    15601 tccacagttt gaggatgtaa acgaccaagt ggccatagat atcctcagca agtgtttccc
    15661 agaccgtaaa gttgtcggaa taccagccag agatattctc ttaggtggtg gtaatatcca
    15721 ctgtatcacc caacaaattc cagaatagga gaaaaagatg agaaatgtaa gagttgcaac
    15781 cattcagatg caatgcgcta aggatgtggc aacaaatatc caaaccgcag agcgtttagt
    15841 acgtcaggct gctgagcaag gagcccaaat tattctcttg cccgagttgt ttgaacatcc
    15901 ctatttctgt caggaacgtc agtatgacta ctaccagtat gcccaatctg tagcggaaaa
    15961 tactgccatt cagcatttta aggtgattgc taaggaacta caagttgttt taccaatcag
    16021 tttctatgaa aaagatggta atgtcttgta taactctatt gccgtcattg atgcagatgg
    16081 ggaagtgctg ggcgtttatc gaaagaccca cataccagat gaccattatt atcaagaaaa
    16141 attctatttc acgcctggta acactggttt caaggtctgg aatactcgct atgctaagat
    16201 tggtatcggt atctgttggg atcaatggtt ccctgaaaca gcgcgctgtc ttgcattgaa
    16261 tggtgctgaa ttgctctttt atcctacagc tatcggttca gagccaattt tggatacaga
    16321 tagttgtggt cactggcaac gtactatgca agggcacgca gcagcgaata ttgttccagt
    16381 catcgcagcc aatcgttatg gtttagagga ggttactcct agtgaggaaa atggcggaca
    16441 gagttccagt cttgacttct acggttcctc ctttatgacg gatgaaacag gagctattct
    16501 agaacgagct gaaagacaag aagaagctgt tctgttagct acttatgacc tagacaaggg
    16561 agcaagtgaa cgcctaaact ggggcttgtt tcgagataga agaccagaaa tgtatagaca
    16621 aattacagat tagtgtggga gaaatgagag attcattctg ctagactaac ttcttattag
    16681 caactataag atactatggc atctagtaaa tcgattttta tgattcgcta ttcttgtcta
    16741 ttgattagtc cgtattttaa aatattagca aaaaagcaaa tagcagtaac ttctgtctat
    16801 ttgcttttct tttttataga atatatttct caatagcacg cgcaacgccg tcttcttcgt
    16861 tgcttgaggt aacggcatcc gcaagagatt tgacataatc gctggcattt cccattgcaa
    16921 tcccaagccc tgcaaactgg agcatttcga tatcgttatt agcatcgccc atggccataa
    16981 tctctgagga atcaatcttc aaaatctcag ctagtcgtga aagagcagta gcctttgtcg
    17041 ttccaagcgg cattgcttca taaatgacag gctgcgaacg aactccactg aatcgttggc
    17101 aaagctcttc agcaaaacgc tgctcaaaat cgtctgtttg ttcttttgtt cctaaaaaca
    17161 taccttggaa catccgtaac tttccactag tcgcttcttc aagagaaatt tcagtcaggt
    17221 ctgaaaatac tagtttagca tcattttcaa taacttgatt gggtttgcca ccgagaacaa
    17281 aataatgtga ctcgtcaaaa agtgtcaact gaacatcact cttttcagca aggtcataga
    17341 ggtattcgat gtcagctgga ctaagttctt gccagtcaac caagccccag tcgctagtct
    17401 ggtgagttga acaaccgttg ttaacaatca catactcatt ctggaggtcg agtcccagtt
    17461 ttttgtagta ggggaggaca ccgaaaaggg ggcgacccgt acagagaacc agtttgacac
    17521 ctttttcaat ggcttggtga atagcagcga tgtgagcctg tgggatttcc ttggcttcat
    17581 tgaggagggt tccatccata tccaaggcta gtagtttaat cataggtctt ccttctttat
    17641 cttttgctat tattatagca tattttggag aagaaattga tagaaagctt gagactaatt
    17701 gattttatag tttaagatgt tttgatgaca attcatgatt tgaagaggat atttggcaaa
    17761 gatatgctat actatgtttg tcaatgttgc aactagacaa attaaaaaac caacttaata
    17821 taatagtttt tttgtaagta ggtatgagta tcagattact caactaatct gaagaataat
    17881 ggaggaaata tatcatgatt ttaatgacaa aaaatataaa tctaacaaat gaagaattag
    17941 agctgataca aggtggagca gatccatatg gtaaaaatcc taatggtagg tacgattggg
    18001 aaatagaacc agtattaact ctgccggttc atggattttg tcccagaggc acctatgatt
    18061 taggatatat tggaggaggc aatcatcttt gcaaaggaag tgctgcgaga ttttaagtaa
    18121 aatttattag taatatgaag aaacaagtgg agaaagcaga gaatttaata tgaaaaaacg
    18181 ggctattcaa attttactag cattgtcctt aattttttac aaatcaactt ggttttggag
    18241 agttttcaat cacctcgcaa agccctatct accagcaagt cgtgaatttt ttcagattct
    18301 gcttttgatg gagagcggag ttcttttctt agcggtcatc tatctactgg tttttgcagg
    18361 aaagaaaatt tttcatttca agtggcagct gaggtacttc atctaccttt tactgggcta
    18421 catcatttca tatatgtctg acttcctctt ttcgtatttc atatccctgt cttcaaatca
    18481 gatttctttg aatgaaacgg tagaaatgat ggggagacag gagttccctt atttcttgct
    18541 catcgtttgc ttcatcgccc ctattgctga ggaattgatt tatcgaggtg tgcttatgac
    18601 aacctttttc aaaaactcac cttggtacgg agatgttttg ctttctgcta ttattttcgg
    18661 ttatattcat atcaattttg ctttaactcc tcttgctttt ttcatttatg ctagtggagg
    18721 tcttatttta gctctattgt atcgcatgac taaaaatctc tactatccaa tactagttca
    18781 tattctcatc aatatcactg ccttctggga tgtttggtta ctcctatttt caggaagtta
    18841 gcttactaaa aaaatgtcgg aattttccgg cattttcttt tttcacaaat agtcaacgtt
    18901 tttctttccg atactgaagt ggtgtgtagc cacttatttt tttgaattga ttttgaaaat
    18961 aagattggcg tgagaaaggc agatagtgaa gatagttaag aagaatagga tgttcttttt
    19021 tcctttttgg aaaacttcta aaatatggta taatgaaaag ataaagaagt tgggggtaga
    19081 agatgaacat tcaacaatta cgctatgttg tggctattgc caatagtggt acttttcgtg
    19141 aagctgctga aaagatgtat gttagtcagc cgagtctgtc tatttctgtt cgtgatttgg
    19201 aaaaagagtt gggctttaag attttccgtc ggaccagctc agggactttc ttgacccgtc
    19261 gtgggatgga attttatgaa aaagcgcaag aattggttaa aggatttgat atttttcaaa
    19321 atcagtatgc caatcctgaa gaagaaaaag atgaattttc cgttgctagc cagcactatg
    19381 acttcttacc accaactatt acggcctttt cagagcgcta tcctgactat aagaacttcc
    19441 gtatttttga atcaactact gttcaaatat tagatgaagt ggcgcaaggg catagtgaga
    19501 ttgggattat ctacctcaac aatcaaaata aaaaggggat tatgcaacgg gttgaaaagt
    19561 taggtctgga ggtcatcgaa ttgattcctt tccataccca tatttatctc tgtgagggtc
    19621 atcctttagc tcagaaagag gaattagtca tggaggattt agcggattta ccaacggttc
    19681 gtttcactca agagaaagac gagtaccttt attattcaga gaactttgtc gataccagcg
    19741 ctagctcaca gatgtttaat gtgacagacc gtgccacctt gaatggtatt ttggagcgga
    19801 cggacgccta tgcgacaggt tctggatttt tagatagtga cagtgttaat ggcattacag
    19861 ttattcgtct caaggataac ctagataacc gcatggtcta tgttaaacgt gaagaagtgg
    19921 agcttagtca agctgggact ctcttcgtag aagtcatgca agaatatttt gatcaaaaga
    19981 ggaaatcatg aaaaaaagag caatagtggc agtcattgta ctgcttttaa ttgggctgga
    20041 tcagttggtc aaatcctata tcgtccagca gattccactg ggtgaagtgc gctcctggat
    20101 tcccaatttc gttagcttga cctacctgca aaatcgaggt gcagcctttt ctatcttaca
    20161 agatcagcag ctgttattcg ctgtcattac tctggttgtc gtgataggtg ccatttggta
    20221 tttacataaa cacatggagg actcattctg gatggtcttg ggtttgactc taataatcgc
    20281 gggtggtctt ggaaacttta ttgacagggt cagtcagggc tttgttgtgg atatgttcca
    20341 ccttgacttt atcaactttg caattttcaa tgtggcagat agctatctga cggttggagt
    20401 gattatttta ttgattgcaa tgctaaaaga ggaaataaat ggaaattaaa attgaaactg
    20461 gtggtctgcg tttggataag gctttgtcag atttgtcaga attatcacgt agtctcgcga
    20521 atgaacaaat taaatcaggc caggtcttgg tcaatggtca agtcaagaaa gctaaataca
    20581 cagtccaaga gggtgatgtc gtcacttacc atgtgccaga accagaggta ttagagtatg
    20641 tggctgagga tcttccgcta gaaatagtct accaagatga ggatgtggct gtcgttaaca
    20701 aacctcaggg aatggttgtg cacccgagtg ctggtcatac cagtggaacc ctagtaaatg
    20761 ccctcatgta tcatattaag gacttgtcgg gtatcaatgg ggttctgcgt ccagggattg
    20821 ttcaccgtat tgataaggat acgtcaggtc ttctcatgat tgctaaaaac gatgatgcgc
    20881 atctagcact tgcccaagaa ctcaaggata aaaagtctct ccgcaaatat tgggcgattg
    20941 ttcatggaaa tctgcctaat gatcgtggtg taattgaagc gccgattggc cggagtgaaa
    21001 aagaccgtaa gaaacaggct gtaactgcta aagggaagcc tgcagtgacg cgttttcacg
    21061 tcttggaacg ctttggcgat tatagcttag tagagttgca actggagaca gggcgcactc
    21121 atcaaatccg tgtccacatg gcttatatcg gccattcagt cgctggtgat gaggtctatg
    21181 gtcctcgcaa gactttgaaa ggacatggac aatttcttca tgccaagact ttaggtttta
    21241 ctcatccgag aacaggtaag accttggaat ttaaagcaga tatcccagag atttttaagg
    21301 aaaccttgga gagattgaga aagtaagaat gaaaaagaaa ttaactagtt tagcacttgt
    21361 aggcgctttt ttaggtttgt catggtatgg gaatgttcag gctcaagaaa gttcaggaaa
    21421 taaaatccac tttatcaatg ttcaagaagg tggcagtgat gcgattattc ttgaaagcaa
    21481 tggacatttt gccatggtgg atacaggaga agattatgat ttcccagatg gaagtgattc
    21541 tcgctatcca tggagagaag gaattgaaac gtcttataag catgttctaa cagaccgtgt
    21601 ctttcgtcgt ttgaaggaat tgggtgtcca aaaacttgat tttattttgg tgacccatac
    21661 ccacagtgat catattggaa atgttgatga attactgtct acctatccag ttgaccgagt
    21721 ctatcttaaa aaatatagtg ataatcgtat tactaattct gaacgtctat gggataatct
    21781 gtacggttat gataaggttt tacagactgc ttcagaaaaa ggtgtttcag ttattcaaaa
    21841 tatcacacaa ggggatgctc attttcagtt tggggacatg gatattgagc tctataacta
    21901 tgaaaatgaa accgattcat cgggtgaatt aaagaaaatt tgggatgata attccaattc
    21961 cttgattagt gtggtaaaag tcaatggcaa gaaaatttac cttgggggcg acttagataa
    22021 tgttcatgga gcagaagaca agtatggtcc tctcattgga aaagttgatt tgatgaagtt
    22081 taatcatcat ttagatacaa aaaattctaa tacaaaaaat tttataaaaa atttgtctcc
    22141 tgagataatt gttcaaactt cctcctcacc aattggttcg tatgatagcg gtcaagaaat
    22201 aaatagggaa tatattagtt ggcttgaatc aatgggaatt caacatataa atgcagccag
    22261 caaagactat gatgcaacag tttttgatat tcgacaagac ggtttagtaa acatttcaac
    22321 ttcctacaag ccgattccaa gttttcaagc tggttggcat aagagttcat atggaaactg
    22381 gtggtatcaa gcgcctgatt ctacaggaga atatgctgtc ggttggaatg aaattaaggg
    22441 tgaatggtat tactttaacc aaacgggtat cttattacag aatcaatgga aaaaatggaa
    22501 caatcgttgg ttctatttga cagactctgg tgttgctgct aaaaattgga agaaaatcgc
    22561 tggaatctgg tattatttta acaaagaaaa ccagatggaa attggttgga ttcaagataa
    22621 agagcagtgg tattatttgg atgttgatgg ctctatgaag acaggttggc ttcaatataa
    22681 ggggcaatgg tattactttg ctccatcagg ggaaatgaaa acgggctggg taaaagataa
    22741 agaagcctgg tactatatgg attctactgg tatcatgaag acaggtgaga tagaagttgc
    22801 tggacatcat tactatctag aagaatcagg agctatgaag caaggctggc ttaaaaaggc
    22861 aaatgattgg tatttctaca agacagatgg ttcacgagct ataggttgga ttaaagacaa
    22921 ggataaatgg tacttcttga aagaaaatgg tcaattactt gtgaatggta agacaccaga
    22981 aggctatact gtggattcaa gtggtgcctg gttagtggat gttccgatcg agaaatctgc
    23041 tacaattaaa actacaagtc attcagaaat aaaagaatcc aaagaagtag tgaaaaagga
    23101 tcttgaaaat aaagaaacga gtcaacatga aagtgttaca aattcttcaa ctagtcaaga
    23161 tttgacatcc tcaacttcac aaagctctga aacgagtgta aacaaatcgg aatcagaaca
    23221 gtagtagaaa agaaggtttt agggccttct ttttcctatc aactcttttc tatttcctgt
    23281 tattcatgtt ataatggata aatatgaata atcggagtga gactatgaaa tacaaacgga
    23341 ttgtctttaa ggtgggtact tcttctctga caaatgagga tggaagttta tcacgtagta
    23401 aggtaaagga tattacccag cagttggcta tgctgcacga ggctggtcat gagttgattt
    23461 tggtgtcttc aggtgccatt gcggctggtt ttggagcctt aggatttaaa aagcgtccga
    23521 ctaaaattgc tgataaacag gcttcagcag cggtagggca ggggcttttg ttggaagaat
    23581 atacaaccaa tcttctcttg cgtcaaatcg tttctgcaca aatcttgctg acccaagatg
    23641 actttgtgga taagcgtcgt tataaaaatg cccatcaggc tttgtcggtt ttgctcaacc
    23701 gtggggcaat tcctatcatc aatgagaatg atagtgtcgt tattgatgag gtcaaggttg
    23761 gggacaatga cactctaagt gcccaagtag cggcgatggt ccaagcagac cttttggttc
    23821 tcttgacaga tgtggacggt ctctatactg gaaatcctaa ttcagatcca agagccaaac
    23881 gcttggagag aatcgagacc atcaatcgtg agattattga tatggctggt ggagctggtt
    23941 cgtcaaacgg aactgggggt atgttaacca aaatcaaggc tgcaactatc gcgacggaat
    24001 caggagttcc tgtttatatc tgctcatcct tgaaatcaga ttccatgatt gaggcggcag
    24061 aggagaccga ggatggttct tactttgttg ctcaagagaa ggggcttcgt acccagaaac
    24121 aatggcttgc cttctatgct cagagtcaag gttctatttg ggttgataaa ggggctgcgg
    24181 aagctctctc tcaacatgga aagagtcttc tcttatctgg tatcgttgaa gcagaaggag
    24241 tcttttctta cggtgatatc gtgacagtat ttgacaagga aagtggaaaa tcacttggaa
    24301 aaggacgcgt gcaatttgga gcatctgctt tggaggatat gttgcgttct caaaaagcca
    24361 agggtgtctt gatttaccgt gacgactgga tttccattac tcctgaaatc caactacttt
    24421 ttacagaatt ttagaggtaa actatggtga gtagacaaga acaatttgaa caggtacagg
    24481 ctgttaaaaa atcgattaac acagctagtg aagaagtgaa aaaccaagcc ttgctagcca
    24541 tggctgatca cttagtggct gctactgagg aaattttagc ggctaatgcc ctcgatatgg
    24601 cagcggctaa ggggaaaatc tcagatgtga tgttggatcg tctttatttg gatgcagatc
    24661 gtatagaagc gatggcaaga ggaattcgtg aagtggttgc cttaccagat ccaatcggtg
    24721 aagttttaga aacaagtcag cttgaaaatg gtttggttat cacaaaaaaa cgtgtagcta
    24781 tgggtgtcat cggtattatc tatgaaagcc gtccaaatgt gacgtctgat gcggctgctt
    24841 tgactcttaa gagtggaaat gcggttgttc ttcgtagtgg taaggatgcc tatcaaacaa
    24901 cccatgccat tgtcacagcc ttgaagaagg gcttggagac gactactatt catccaaatg
    24961 tgattcaact ggtggaggat actagccgtg aaagtagcta tgctatgatg aaggccaagg
    25021 gctatctaga ccttctcatt cctcgtggag gagctggctt gatcaatgca gtggttgaga
    25081 atgcgattgt acctgttatc gagacaggga ctgggattgt ccatgtctat gtggataagg
    25141 atgcagacga agacaaggcg ctgtctatca ttaacaatgc taaaaccagt cgtccttctg
    25201 tttgtaatgc catggaggtt ctgctggttc atgaagacaa ggcagcaagc ttccttcctc
    25261 gcttggagca agtgttggtt gcagatcgaa aagaagctgg gttggaacca attcaattcc
    25321 gcctagatag caaagcaagc cagtttgttt caggtcaagc tgctcaagca caagactttg
    25381 ataccgagtt tttagactat attctagctg ttaaggttgt gagcagttta gaagaagcga
    25441 ttgcgcatat tgaatcccac agtacccatc attcggatgc cattgtgacg gaaaatgctg
    25501 aagctgcagc atactttaca gatcaagtgg actctgcagc ggtgtatgtt aatgcctcaa
    25561 ctcgtttcac agatggagga caatttggtc ttggttgtga aatggggatt tctactcaga
    25621 aattgcacgc gcgtggtccc atgggcttga aggaattgac tagctacaag tatgtggtca
    25681 ctggtgatgg acagataagg gagtaagaga tgaagattgg atttatcggt ttggggaata
    25741 tgggtgctag tttagccaag tctgtcttgc aggctagacc gtcagatgag attctccttg
    25801 ccaatcgtag tcaagtcaag gtggatgctt tcatcgctaa cttcggtggt cagacttcta
    25861 acaatgaaga aatattcgaa gaagcagatg tgatttttct aggtgttaag cctgctcagt
    25921 tttctgaact gctttctcaa taccagacca tccttgaaaa aagagaaagt cttcttttga
    25981 tttcgatggc agctggattg accttagaaa aactagcaag tcttatccca agccaacacc
    26041 gaattattcg tatgatgcct aatacccctg cttctatcgg gcaaggagtg attagttatg
    26101 ccttgtctcc taattgcagg gctgaggaca gtgagatctt ttgtcagctt ttagccaagg
    26161 ctggtctctt ggttgaatta ggagaaagct taatcaatgc agcgacaggt cttgcaggtt
    26221 gtggaccagc ctttgtctat ctctttattg aggccttggc agatgcaggt gttcagacgg
    26281 gattaccacg agaaacagcc ttgaaaatgg cagcccaaac tgtggtagga gctgggcaat
    26341 tggtcctaga aagccagcaa catcctggag ttttgaaaga tcaagtttgt agtccaggcg
    26401 gttcgactat tgctggcgta gcaagcttag aagcgcatgc ttttcgaggc acagtcatgg
    26461 aggcagttca tcaagcctat aaacgaacac aagaactagg taaataagag gtagctttga
    26521 ctgcctcttt tatggtggtt gatactcttc gaaaatcaaa ttcaaactgc gtcagcttca
    26581 ccttgccgta ctcaagtaca gcctgcggct agcttcctag tttgctcttt gattttcatt
    26641 gagtatgaaa tgagaagaca aaaagattgt cacaaacccc tatttttttg atagaataga
    26701 agtagtaaaa aagaaatgag ttagacatgt caaaaggatt tttagtctct cttgagggac
    26761 cagagggagc aggcaagacc agtgttttag aggctctgct accaatttta gaggaaaaag
    26821 gagtagaggt gttgacgacc cgtgaacctg gcggagtctt gattggggag aagattcggg
    26881 aagtgatttt ggatccaagt catactcaga tggatgctaa aacagagcta cttctctata
    26941 ttgccagtcg cagacagcat ttggtggaaa aagttcttcc agcccttgaa gctggcaagt
    27001 tggtcatcat ggatcgtttt atcgatagtt ctgttgccta tcagggattt ggtcgtggct
    27061 tagatattga agccattgac tggctcaatc agtttgcgac agatggcctc aaacccgatt
    27121 tgacactcta ttttgacatc gaggtggaag aagggctggc tcgtattgct gctaatagtg
    27181 accgcgaggt taatcgtttg gatttggaag ggttggactt gcataaaaaa gttcgtcaag
    27241 gctacctttc tcttctggat aaagagggaa atcgcattgt caagattgat gctagtctcc
    27301 ctttggagca agttgtggaa actaccaagg ctgtcttgtt tgacggaatg ggcttggcca
    27361 aatgaaacaa gatcaactaa aggcttggca accagctcag tttgaccgtt ttgtccgtat
    27421 cttagaacaa gaccagctca atcacgccta tctcttttca ggtttctttg gaagcttgga
    27481 aatagcgcaa tttttagcta agagcctctt ttgtacggat aaagttggcg tcttaccatg
    27541 tgagaaatgc cgaagttgca agctgattga acagggagaa tttcccgatg tcaccttgat
    27601 taagccagtc aatcaggtca tcaagacaga acgcattagg gaattggtgg gacagttttc
    27661 tcaagcaggg attgaaagcc agcaacaggt ctttattatc gagcaagcgg ataaaatgca
    27721 tcccaacgca gccaattctc tgctcaaggt catcgaagaa ccccagagtg aagtttatat
    27781 tttcttcttg actagcgatg aggaaaagat gttaccgaca atccgaagtc ggactcagat
    27841 cttccacttt aaaaagcaag aagaaaaact tatcttactc ttagaacaaa tgggacttgt
    27901 taagaaaaaa gcgactcttt tagctaagtt tagtcaatcg cgagctgaag cagaaaagtt
    27961 ggctaatcag gcaagttttt ggaccttggt cgatgaaagt gaacgcctgc tgacttggtt
    28021 agtagctaag aaaaaagaaa gttatctaca ggttgccaaa ttagccaact tggcagatga
    28081 taaggaaaaa caggatcagg ttttacggat tcttgaagtt ctctgcgggc aagacctctt
    28141 gcaggtaaga gtaagagtga ttctacaaga tttactagaa gctagaaaaa tgtggcaagc
    28201 taatgtcagc tttcaaaatg ccatggaata tctggtcttg aaagaaatat aaactcaaaa
    28261 atgaatgata aagaaaggaa agggctgttt tatggacaaa aaagaattat ttgacgcgct
    28321 ggatgatttt tcccaacaat tattggtaac cttagccgat gtggaagcca tcaagaaaaa
    28381 tctcaagagc ttggtagaag aaaatacagc tcttcgcttg gaaaatagta agttgcgaga
    28441 acgcttgggt gaggtggaag cagacgctcc cgtcaaggcc aagcatgttc gcgaaagtgt
    28501 ccgtcgtatt taccgtgatg gatttcacgt atgtaatgat ttttatggac aacgtcgaga
    28561 gcaggacgaa gaatgtatgt tctgtgatga gttgttatac agggagtaag catgcaaatt
    28621 caaaaaagtt ttaaggggca gtctccctat ggcaagctgt atctagtggc aacgccgatt
    28681 ggcaatctag atgatatgac ttttcgtgct atccagatct tgaaagaagt ggactggatt
    28741 gctgctgagg atacgcgcaa tacaggtctt ttgctcaagc attttgacat ttccaccaag
    28801 cagatcagtt ttcatgagca caatgccaag gaaaaaattc ctgatttgat tggtttcttg
    28861 aaagcagggc aaagtattgc tcaggtctct gatgccggtt tgcctagcat ttcagaccct
    28921 ggtcatgatt tggttaaggc agctattgag gaagaaattg cagttgtgac agttccaggt
    28981 gcctctgcag gaatttctgc cttgattgcc agtggtttag cgccgcagcc acatatcttt
    29041 tacggctttt tgccgagaaa atcaggccag caaaagcaat ttttcgactc gaaaaaagac
    29101 tatcctgaaa ctcagatttt ttatgaatca cctcatcgtg tagcagacac gttggaaaat
    29161 atgttagaag tctacggtga ccgctccgtt gtcttggtca gggaattgac caaaatctat
    29221 gaagaatacc aacgaggtac tatctctgag ttattagaaa gcattgctga aacgccactc
    29281 aagggcgaat gtcttctcat tgttgagggt gccagtcagg gtgtggagga aaaggacgag
    29341 gaagacttgt tcgtagaaat tcaaacccgc atccagcaag gtgtgaagaa aaaccaagct
    29401 atcaaggaag tcgctaagat ttaccagtgg aataaaagtc agctctacgc tgcctaccac
    29461 gactgggaag aaaaacaata aagggagaca ggatgtaata attctgtctg tttctgttta
    29521 acttaattag tgatgataat ataaagatgt atcacttggt atagaagctt tggtattaag
    29581 ttttttatta agcccatacg gaataccgat ggttggagca gcagttatag cgttcttaga
    29641 aggtataaat agaaaaataa ggtcatttta aatcaaagga ttgataaatc agaaagaagg
    29701 tgattttttg cgaacatacg aaaataaaga agaactaaaa gctgagatag agaaaacatt
    29761 tgagaaatat attttagaat ttgataatat tccagaaaat ttaaaagata agagagctga
    29821 tgaagttgac agaactccag cagaaaacct tgcttatcag gttggttgga ccaacttggt
    29881 tcttaaatgg gaagaagatg aaagaaaggg gcttcaagta aaaacaccat cggataaatt
    29941 taaatggaat caacttggtg aattatatca gtggttcaca gatacctacg ctcatttatc
    30001 tctgcaagag ttgaaagcaa aattaaatga aaatattaat tctatctctg caatgattga
    30061 ttcgttgagt gaggaagaat tatttgaacc gcatatgaga aagtgggctg atgaagcgac
    30121 taaaacagcg acttgggaag tgtataagtt tattcatgta aatacggttg caccttttgg
    30181 aactttcaga actaaaatca gaaaatggaa gaagatagta ttataaatta tatttttaac
    30241 tttaaaaaat ttcataaaaa tggttaccaa aggcgataga agaaaaacta tcgtcttttt
    30301 ctttgcaaat ttttaagaag ggaggtgatc ttgcatggac tttgaatatt tttataacag
    30361 agaagcggaa agatttaact tcttaaaagt accggagata ttagttgata gagaagaatt
    30421 tcggggctta tcagcagaag caattatcct ttattccata cttcttaaac agacaggaat
    30481 gtcatttaag aataactgga tagacaagga aggcagagta tttatctatt ttactgtcga
    30541 agaaattatg aaaagaagaa atatctcaaa gccaactgcc ataaaaacat tagatgagct
    30601 tgatgtaaaa aaaggaatag gactgatcga aagagtaagg cttggacttg gtaagccgaa
    30661 catcatttat gttaaagact ttatgagtat atttcaggta aaagaaaatg acttacagaa
    30721 gtcaaaaaac ttaacttcag aagtaaaaga ttttaacctc agaagtaaag aaaatgaact
    30781 tcaagaggtt aagaaccttg actctaacta tatagagaat aataagagta agtatagtaa
    30841 gagagaatat agttttggtg aaaacggact tggaacattt caaaatgtgt ttttagctgc
    30901 tgaagatata tcggatttac aaatcataat gaactcacag cttgagaatt acattagact
    30961 tcctgcaaaa ctagaatcct agttcatgat tgataatacc agcaatcaaa ttcattcgta
    31021 atccgaagcg tttacgatga tttcgatagg ttgttgaaaa cattttaaac gtttttactt
    31081 tggcaaagat gttctcaacc ttgcttctct ccttagatag cgcatggtta caggctttat
    31141 cttcaactgt tagcggtttg agtttgctgg atttacgtgg agtttgtgct tgaggatata
    31201 tcttcgtgag tccttgataa ccactgtcag ccaagatttt accagcttgt ccgatatttc
    31261 tgcgactcat tttgaacaac ttcatatcat aacaatagtt cacagtgata tccaaagaaa
    31321 caattctccc ttgacttgtg acaatcgttt gagccttcat agcgtggcat ttctttttac
    31381 cataataatt cgctaattgt ttttttaggg cgattgattt ttacttccgt cgcatcaatc
    31441 attaccgtgt cctcagaact gagaggagtt cttgaaatcg taaaaccact ttgaacaaga
    31501 gttacttcaa cccattggct ccgatggatt aagttgcttt cgtgaatacc aaaatcagcc
    31561 gcaatttctt cataagtgcg gtattctcgc atatattgaa gagtggtcat aagaaggtct
    31621 tctaggctta atttaggttt tcgtccacct tttgcatgtt taagttgata agctgttttt
    31681 aatacagtta acatctcttc aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt
    31741 gcatcagtta gttgtttact tgcttcatca ttcatagaac tactatacca tattttgttt
    31801 cgcaggaagt ctattggaaa gtaagaaata ttgaagctga ggctattaga agaaattgtg
    31861 agcgtggtgc tattttttca ggtaaaataa aatatcacga agattcacag tttaaaggag
    31921 atcactatgt tgaatgttat gctgttttag ataatacggt tatagcaaga gatagaataa
    31981 cagtccctat cgatccgtta tgtggaaaag attttataga gtagcatata attgattctt
    32041 aactggaata ctcactatct ctttacatca agaaaatgac taaacaggga agtttgcctt
    32101 cttccctttt tttgttatac tagtagaaga aaaaatagaa agatttgtgg gagtgaaaaa
    32161 gtcctgtgga ctttttcagc ctgagccaag aaactcgaaa gctcgtaagt ctgattggct
    32221 ttttcaatgt gaatcttaac ttcatactcc caaagaggta ttagtgtcgt gtctcaatct
    32281 tatatcaatg ttatcggtgc tggtttggca ggttctgaag cagcctacca aatcgcagag
    32341 cgtggtattc cagttaaact ttatgaaatg cgtggtgtca agtcaacacc tcagcacaaa
    32401 acagacaatt ttgctgagtt ggtttgttcc aattccttgc gtggagatgc tttgacaaat
    32461 gctgttggcc tccttaagga agaaatgcgt cgcttgggtt ctgtgatttt ggaatctgct
    32521 gaggctacac gtgttcctgc aggtggtgcc cttgcagtgg accgtgatgg tttctctcaa
    32581 atggtgaccg aaaaagttgc caaccacccc ttgattgaag tggttcgtga tgaaattaca
    32641 gaattgccga cagatgttat tacggttatc gctactggtc ctttgacaag tgatgccttg
    32701 gctgaaaaga ttcatgccct taatgacggt gatggttttt atttctacga tgcggcagcg
    32761 cctattatcg atgtcaacac tatcgatatg agcaaggtct acctcaaatc acgttatgat
    32821 aagggagaag cggcctacct caatgcccct atgaccaagc aagaatttat ggatttccat
    32881 gaagctttgg tcaatgcaga agaagcaccg cttaattctt ttgaaaaaga aaagtacttt
    32941 gaaggatgta tgcctatcga agtcatggcc aaacgtggca ttaaaaccat gctttatggt
    33001 cctatgaaac cagttggtct tgagtatccg gacgactaca caggacctcg tgatggagaa
    33061 tttaaaacac cttatgcggt tgtccagctc cgtcaggata atgcagctgg tagcctatac
    33121 aatattgttg gtttccagac ccacctcaaa tggggagaac aaaagcgtgt cttccaaatg
    33181 attccgggtc ttgaaaatgc ggagtttgtc cgttatggtg tcatgcatcg caattcttac
    33241 atggattcac caaatcttct tgagcagact taccgttcca agaaacaacc aaatctcttc
    33301 tttgctggtc agatgacggg ggtggaaggc tatgttgagt cggcggcttc gggcttagtt
    33361 gcgggaatta acgcagctcg tctcttcaag gaagaaagcg aggttatttt ccccgagacg
    33421 acagcgattg gaagcttagc tcattacatt acccatgccg acagcaaaca tttccaacca
    33481 atgaatgtca attttgggat catcaaggag ttggaaggcg agcgtatccg tgataagaag
    33541 gctcgttatg aaaaaattgc agagcgtgcc cttgccgact tagaggaatt tttgactgtc
    33601 taattttttt gaaagaattg ctcatgatac tataaaaatc ttagaaattg tgataaaata
    33661 ggtaggatga aagaaggaga gtgaaaatgg cgaatcccaa gtataaacgt attttaatca
    33721 agttatcagg tgaagccctt gccggtgaac gtggcgtagg gattgatatc caaacagttc
    33781 aaacaatcgc aaaagagatt caagaagttc atagcttagg tatcgaaatt gcccttgtta
    33841 ttggtggagg aaatctttgg cgtggagaac ctgcagcaga agcaggtatg gaccgtgttc
    33901 aggcagatta cactggaatg cttgggactg ttatgaatgc tcttgtgatg gcagattcat
    33961 tgcaacaagt tggggttgat acgcgtgtac aaacagctat tgctatgcaa caagtggcag
    34021 agccttatgt ccgtggacgt gcccttcgtc accttgaaaa aggccgtatc gttatctttg
    34081 gtgctggaat tggttcacca tacttctcga cagatacaac agcggccctt cgtgcagctg
    34141 aaatcgaagc agatgccatc ctcatggcta aaaatggcgt cgatggtgtg tacaatgccg
    34201 atcctaagaa ggacaagaca gccgttaagt ttgaagaatt gacccaccgt gatgttatca
    34261 acaaaggtct tcgtatcatg gactcaacag cctcaaccct ctcaatggac aacgacattg
    34321 acttggttgt cttcaacatg aaccaatcag gcaacatcaa acgtgtcgta tttggtgaaa
    34381 atatcggaac aacagtttca aataatatcg aagaaaagga ataagaaaga atatggctaa
    34441 cgtaattatt gaaaaagcta aagagagaat gacccaatct caccaatcac ttgctcgtga
    34501 atttggtggt atccgtgctg gtcgtgccaa tgcaagcttg cttgaccgtg tacatgtaga
    34561 atactatgga gtcgaaactc ctcttaacca aatcgcttca attacgattc cagaagcgcg
    34621 tgttttgttg gtaacaccat ttgacaagtc ttcattgaaa gacatcgaac gtgccttgaa
    34681 cgcttctgaa cttggtatca caccggctaa tgacggttct gtgattcgct tggttatccc
    34741 agctcttaca gaagaaactc gtcgtgacct tgctaaagaa gtgaagaagg tcggcgaaaa
    34801 tgctaaagtg gctgtccgca atatccgtcg cgatgctatg gacgaagcta agaaacaaga
    34861 aaaagcaaaa gaaatcactg aagacgaatt gaagactctt gaaaaagata ttcaaaaagt
    34921 aacagacgat gctgttaaac acatcgacga catgactgct aacaaagaga aagaactttt
    34981 ggaagtctaa aaataaacag aaaaactcag ttggcattgc tggctgagtt ttattcgaaa
    35041 gaaggaaata tgaatacaaa tcttgcaagt tttatcgttg gactgatcat cgatgaaaat
    35101 gaccgttttt actttgtgca aaaggatggt caaacctatg ctcttgctaa ggaagaaggt
    35161 caacatacag taggggatac ggtcaaaggt tttgcataca cggatatgaa gcaaaaactc
    35221 cgcctgacaa ccttagaagt gactgccact caggaccaat ttggttgggg acgtgtcaca
    35281 gaggttcgta aggatttggg tgtctttgtg gatacaggcc ttcctgacaa ggaaatcgtt
    35341 gtgtcactcg atattctccc tgagctcaag gaactctggc ctaagaaggg cgaccaactc
    35401 tacatccgtc ttgaagtgga taagaaagac cgtatctggg gcctcttggc ttatcaagaa
    35461 gacttccaac gtcttgctcg tcctgcctac aacaacatgc agaaccaaaa ctggccagcc
    35521 attgtttacc gtctcaagct gtcaggaact tttgtttacc taccagaaaa taatatgctt
    35581 ggttttattc atcctagcga gcgttacgca gagccacgtt tggggcaagt attagatgcg
    35641 cgcgttattg gtttccgtga agtggaccgc actctgaacc tctccctcaa accacgctcc
    35701 tttgaaatgt tggaaaacga tgctcagatg attttgactt atttggaaag taatggcggt
    35761 ttcatgacct taaatgataa gtcatctcca gacgacatca aggcaacctt tggcatttct
    35821 aaaggtcagt tcaagaaagc tttaggtggt cttatgaagg ctggtaaaat caagcaggac
    35881 cagtttggga cagagttgat ttagggaggc ttatgagaaa atcattttac acttggctca
    35941 tgaccgagcg caatcctaaa agtaacagtc ccaaagcaat tttggcagac ctcgcttttg
    36001 aagaggcagc ttttccaaaa catacagatg attttgatga ggtcagtcgc tttttggagg
    36061 agcatgccag tttctctttt aacctaggag attttgacag catttggcag gaatatctag
    36121 aacactagca tttattcatt gggtttgggc tagtaatttc tccatccctc tgctataata
    36181 aaaagaaata aaaggattag agaggttctt tatttgaagg aacattcaat agacattcaa
    36241 ctgagtcatc cagatgacct gtttcatctt tttggttcca atgaacgcca tcttcgtttg
    36301 atggaagaag agcttgatgt tgtgattcat gctcgtacgg agattgtcca ggttttggga
    36361 gaagagtctg cctgtgagga agcccgtcaa gttattcagg ctttgatggt cttggtaaat
    36421 cgtgggatga ccgttggtac gccagatgta gtcactgcga ttagcatggt caaaaatgat
    36481 gaaattgaca agtttgtcgc cctttacgaa gaagaaatta tcaaagataa tactgggaaa
    36541 cctatccgtg tcaaaacact agggcaaaag ctttatgtgg acagtgtcaa acagcatgat
    36601 gtgacctttg gaattgggcc agcaggtaca gggaagacct tccttgcagt gaccttggca
    36661 gtgactgccc ttaaacgtgg gcaagtcaag cgaattatcc taactcgtcc agcggtggaa
    36721 gcgggagaga gtcttggatt tcttccgggt gatcttaagg agaaggtgga tccttacctt
    36781 cgtcctgttt acgatgcctt gtatcaaatt cttgggaaag accaaacgac tcgtctcatg
    36841 gagcgtgaaa ttatcgaaat tgcgcccctt gcctatatgc gtggccggac cttggatgat
    36901 gcctttgtca ttctcgatga ggcgcaaaac acgaccatca tgcagatgaa gatgttcttg
    36961 acgcgtttag gctttcattc taagatgatt gtcaatggag atatcagtca gattgacctg
    37021 ccacgtaatg tcaagtccgg tttgattgat gctcaagaga aactcaagaa catccatcag
    37081 attgactttg ttcatttttc agccaaggat gtggttcgcc atccagttgt cgctcagatt
    37141 atccgagcct atgaatattc tactgaagtt gcacacgact gattttgagg aagttcgcct
    37201 gcaaaagaat atacttttga gagaggaaaa tccagttgta taggctaaag gttttatcca
    37261 aaggtctgag acaacgatta ggcacgatgg aaagaacttt tatgtggctg atgacgatca
    37321 gtgcatcttc ctgtgtcata atcacagggc acaagaaagt aggaatttga aaagatgatt
    37381 gaccaactat ctaagtatta cagttgtagg atactaactg aaaaggatat tccaagtatt
    37441 ttatctttat atgaaagtaa tcctctgtat tttcagcatt gtccaccaga accaaatttt
    37501 gcaactgtaa aagaggacat gctttgtcta cctgaaggta aagctaaggc tgataagttt
    37561 tttgttggat tttggaatgg atctgacctt gtggctgtta tggattttgt ctatgcatat
    37621 cctgatgagg agactgtttt tattggtttg tttatggttg atcaagccta tcagaggaaa
    37681 gggattggta gtcatattgt gacagaagca ctagcttatt ttgctaagaa ctttcgaaag
    37741 gcacgtttgg cttatgttaa gggaaatccg caatctcagc atttttggga aaagcagggc
    37801 tttaaatcaa ttggatgcga ggttaagcaa gaactctata cggttgttat cgctgaacag
    37861 agcctagaag attagaaatg gcatcaagta agaactattt ggaatttgtt ttggaacaat
    37921 tatcaggatt agatgatgtg acttaccgtt ccatgatggg ggagtatatt ctttacttcc
    37981 gcggcaagat tattggcggc atttatgacg atcgcttttt agttaaaccc gtgcaagcag
    38041 tcttagataa gattgaccaa tcttcttttg agtttccata caaaggtgcc aaagaaatga
    38101 tttgagtgga agaacttgat aataagatgt ttctataaga cctgatttta gctatgtata
    38161 accaactgcc aacgcccaaa cctaaaaaga aaaagcaagg gtgaacgaag taaaaaagaa
    38221 gtctgctaag gccctgtctt tgcacgggta aaattttata tataaaaaga agctgggact
    38281 aaagagctca gcttcctttg gtttatataa ttgtcattac aagacgaagt ggttgggcga
    38341 aactctgttg actttattca atttagagtt tcttatgcac aattgagtct ggaacgaaag
    38401 tctccagttg caaagtatac agtacaataa accaacgatg taatagctga tgacacaaag
    38461 cacagtgggt aggacttgcg aagtcaccct tttcttttta aaatttatac taaatcattg
    38521 atatcagtgt agtcacgatt aagtccttga gcaactggta ggttagtcaa gtaaccttga
    38581 taagtagtca caccttgacg caagccttca tcttcagaga ttgcttgtgc gaatcctttg
    38641 ccagccaaag cttcgatata aggaagagtg acattggtta gggcgatggt tgaagtgcgg
    38701 gcaaccgcac cagggatatt ggcaacggca tagtggagaa caccgtgttt ttcatagacg
    38761 ggttcatcgt gcgttgtcac acggtcagct gtttcgataa ggccaccttg gtcaacagca
    38821 acgtcaacga tacagagcct ggacgcattt gtttgaccat ctcatctgtc accaattccg
    38881 gtgcttttgc accagggatg agaatggctc caatcaccac atcagcatct ctcacacttg
    38941 cttcaatgtt gaatgaatta gacataagag tttgaatttg acttccaaag acttcttcta
    39001 gaactgagag acgcttggca ctaatatcta aaatagtcac ttgagcacca agaccaaggg
    39061 cgatgcgggc agcatgtgta ccgacgacac catcaccgat gatagttact tttccttttg
    39121 gaacacctgg tacaccacca agtagaacac cagagccacc agcttgctta gtaaggaagt
    39181 gagctccgat ttgaacagcc atacgacctg caacctcact cataggaacg aggagcggta
    39241 gttgtccttg attgtcacga acagtttcat aggcaattcc tgttgttttt gctgctaaca
    39301 tagcatctgc taattctgga gcagcggcca tgtgcaagta ggtgaagaga agaagatcgt
    39361 cgcgcaagta accgtattca gaacttaaag gttcttttac tttcacaacc aactctgctg
    39421 cccaagcttc accagcagta gcgacaatct cagctccttg cttttgatag tcagcatcag
    39481 taaagccaga accgagacca gcatttgttt cgataaggac acgatgacca cgactaacta
    39541 agctatgaac acctgcaggt gtgagggcga cacggttttc gttattttta atttcttttg
    39601 ggattccgat taacattgag ataacctacc tttcaattga cggtcttgtt ttggttgtca
    39661 cattccagtt cataaatcaa aaatgtgacg gtttcattgt atatgaaacc gcttcaaaaa
    39721 tcaagaaaaa cttgtcatcc caattttttt atgctagact agtgaaaatc aagctctaat
    39781 ggagggaaaa gtatggaatc aatttttgta aaacttgccc agtatccgtc tatagaaacg
    39841 gagcgtttat tgcttagacc tgtaactttg gatgatgcgg aagcaatgtt tgactatgcc
    39901 tcggacaagg gtaatacacg ttacactttt ccaaccaatc aaagcttgga agaaaccaag
    39961 aataacattg ctcagttcta tttggctaat cccttgggac gttggggaat agaactaaaa
    40021 agcaatggtc agtttattgg aaccattgac ttgcacaaga ttgattctgt tcttaagaag
    40081 gcagctattg gctacattat caataaaaag tattggaatc aaggattaac gacagaagcc
    40141 aatcgtgctg tgattgagct agcttttgag aagataggga tgaataagtt gactgccctt
    40201 cacgataagg acaatcctgc gtcaggaaag gtcatggaga aatcaggcat gcgtttttcc
    40261 catgcagaac catatgcttg tatggaccag catgaaaaag gccgaatcgt gacaagagtt
    40321 cattatgtct tgaccaagga agactatttt gcaaataaat aagcagttga aaagaaattt
    40381 ttcgactgtt ttttcttcct cttacgaata atctaagaga ggagaaaata tggaagcaat
    40441 tatcgagaaa atcaaagagt ataaaatcat cgtcatctgt actggtctgg gcttgcttgt
    40501 aggaggattt ttcctgctaa aaccagctcc acaaacacct gtcaaagaga cgaatttgca
    40561 ggctgaagtt gcagctgttt ccaaggactc atcgaccgaa aaggaagtga agaaggaaga
    40621 aaaggaagaa ccccttgaac aagatctaat cacagtagat gtcaaaggtg ctgtcaaatc
    40681 gccagggatt tatgacttgc ctgtaggtag tcgagtcaat gatgctgttc agaaggctgg
    40741 tggcttgaca gagcaagcag acagcaagtc gctcaatcta gctcagaaag ttagtgatga
    40801 ggctctggtt tacgttccta ctaagggaga agaagcagtt agtcaacaga ctggttcggg
    40861 gacagcttct tcaacaagca aggaaaagaa ggtcaatctc aacaaggcca gtctggaaga
    40921 actcaagcag gtcaaaggac tgggaggaaa acgtgctcag gatattatcg accatcgtga
    40981 aacaaatggc aagttcaagt cagtagacga actcaagaca gtctctggca ttggtgctaa
    41041 gaccatagaa aagctaaaag actatgttac agtggattaa gaacatcccc attcccctaa
    41101 tttacctgag ttttttgtta ctttggtttt attacgctat tttctcagca tcctatcttg
    41161 ctttgttggg ctttgttttt ctgctagtct gtctctttat ccaatttccg tggaaatctg
    41221 ctggtaaagt tctaataatt tgcggaatct ttggattttg gtttgttttt caaaattggc
    41281 aacagagtca agcgagtcaa aatctggcgg attctgttga aagggtacgg attttacctg
    41341 atactattaa ggttaatggt gatagtctat cctttcgtgg caagtctaac ggtcgtgctt
    41401 tccaagtcta ttataaactc cagtccgagg aggagaaaga agcctttcaa gctttaaccg
    41461 acctgcatga gataggacta gaagggaagc tttcggagcc agaagggcag agaaattttg
    41521 gtggctttaa ttaccaagcc tatctgaaga ctcagggaat ttaccagact ctcaatatca
    41581 aaacaatcca gtcacttcaa aagattggca gttgggatat aggagaaaac ttgtccagtt
    41641 tacgtcgaaa ggctgtggtt tggattaaga cgcactttcc agaccctatg cgcaattaca
    41701 tgacaggact cttgctggga catctggaca ccgactttga ggagatgaat gagctttatt
    41761 ccagtctagg aattatccac ctctttgccc tatctggtat gcaggtaggt tttttcatga
    41821 atggatttaa gaaacttctc ttgcgattgg gcttgaccca agaaaagttg aaatggctga
    41881 cttatccctt ttcccttatc tatgcgggac taactggatt ttcagcatcg gttattcgca
    41941 gtctcttgca aaagctactg gctcaacatg gggttaaggg cttggataat tttgccttga
    42001 cggtgcttgt cctctttatt gtcatgccaa actttttctt gacagcagga ggagtcttgt
    42061 cctgcgctta tgcttttatc ctgaccatga ccagcaaaga aggggagggg ctcaaggctg
    42121 ttactagtga aagtctagtc atctccttgg gcatattgcc cattctatcc ttctattttg
    42181 cggaatttca accttggtct atccttttga cctttgtctt ttcctttcta tttgacttga
    42241 ccttcttacc gctcttgtct attttatttg tcctttcctt tctctatcca gtcattcagc
    42301 tgaactttat ctttgaatgg ttggagggca ttattcgctt ggtgtcacag gtgacaagta
    42361 gacctctggt ctttggacaa cccaatgcat ggtttttaat cctattgtta atttccttgg
    42421 ctttggtcta tgatttgaga aaaaacatta aaaagctaac ggtattgtgc ttattgatta
    42481 cagggctctt tctcctgacc aagcatccac tggaaaatga aatcaccatg ctggatgtgg
    42541 ggcaaggaga aagtattttc ctacgggatg taactgggaa aaccattctc atagatgtag
    42601 gtggtaaggc agaatcttat aagaaaatcg aaaaatggca agaaaagatg acgaccagca
    42661 atgcccagcg aaccttgatt ccctatctca aaagtcgagg agtagctaag attgaccagc
    42721 taattttgac taacacggac aaggagaatg ttggagattt gtcagaggtg accaaggctt
    42781 tccatgtagg ggagattcta gtatcaaaag acagtctgaa acagaaggaa tttgtggcag
    42841 aactacaggc gactcaaaca aaggtgcgta gtatgacagt aggggagaac ttgcccattt
    42901 ttggaagtca gttagaagtt ctatctccaa ggaaaatggg agatggagga cacgatgata
    42961 ccctagttct gtatgggaaa ttcttggata agcaatttct cttcacggga aatttggagg
    43021 agaaaggaga gaaggacttg ctgaagcact atccagactt gaaagtaaat gttttgaaag
    43081 ctagccaaca tggcaataaa aaatcatcaa gtccagcctt tctagaaaaa ctcaaaccag
    43141 agcttactct tatctcagtt ggaaagagca atcgaatgaa actcccccat caggaaacat
    43201 tgacacgact ggaaggtatc aatagcaaag tttatcgaac tgaccagcaa ggagctatac
    43261 gttttaaggg gttggatagt tggaaaatcg aaagtgttcg ataggaagga taaatgttgt
    43321 agattagtga aataaactaa aaatttgttg cataataatg ataaaaatgg tataatgaaa
    43381 acgtattcaa tattgaggat ataaaatcat taaaaatcat taaaaattag caaaaatcgt
    43441 ttaattagtt agtttataat ctattggtct tcttcagtcc agtgtatctg ctgtgacagt
    43501 cactaaaagt tacaagtatg attggaatac ggtttgggaa tatagtacca actatcacga
    43561 ccatcagtat gcttggattc cgtcatggtc tcgttatgac agctattctg agtataaagt
    43621 tggcggaggc tggaactacg gtcgttatga ggtcataaac tattacagcg gaggctatta
    43681 attcttaaag agtgagaaaa aggagggcta gatatgttgc agcttactca tgtgacctta
    43741 aaaacgcgac aagtcatctt gcaagatgtg gatttcacct ttaaaaaggg tagggtttat
    43801 ggtcttcttg ctatcaatgg ctctggaaag acgaccctat tccgtgccat tagcaattta
    43861 attcccataa gtagtggaaa tatcgcagcc cctccttctt tattttatta tgagagtatt
    43921 gaatggctgg atggaaactt aagtgggatg gactaccttc gtcttatcaa aaacatctgg
    43981 aagtcaggtc tgaacttgag ggatgaaatc gcctattggg aaatgtctga ctatatcagt
    44041 cttcccattc gcaagtattc cttaggcatg aagcaacgct tggtgattgc catgtatttc
    44101 ctcagtcagg ccaaatgctg gctcatggat gagattacaa atggcttaga tgagtattat
    44161 cgacagaagt tttttgatag gctagcacaa atcgatagac aagaacagct ggttctttta
    44221 agttcccact ataaggaaga gttggttgat gtctgcgata gagtagtaac cattcatcag
    44281 gggcagatag aagaggttta gtttatgaaa gatgttagtc tatttttatt gaaaaaagtt
    44341 ttcaaaagcc gcttaaactg gattatctta gctttatttg tatctgtact cggtgttact
    44401 ttttatttta atagtcagac tgcaaactca gtcagcttgg agagagagtt ggaaactcgt
    44461 cttgtagacc gtgagagagt catcaatgaa tatgaagcga aactttccca aatgtctgac
    44521 accagctcgg aggaatacca gtttgctaaa agtaatttag aattgcaaaa aaatcttttg
    44581 aagcgaaaga cagaaattct gactttatta aaagaagggc gctggaaaga ggcctactat
    44641 ctgcagtggc aagatgaaga gaagaattat gaatttgtat caaatgaccc gactgctagc
    44701 tctggcttaa aaatgggggt tgaccgcgaa cggaagattt accaagccct gtatcccttg
    44761 aacataaaag cacatacttt ggagtttccg acccacggga ttgatcagat tgtctggatt
    44821 ttagaggtta tcatcccaag cttgtttgtg gttgcgatta tttttatgct aacacaacta
    44881 tttgcagaaa gatatcaaaa tcatctggac acagctcact tatatcctgt ttcaaaagtg
    44941 acatttgcaa tatcctctct tggagttgga gtgggatatg taactgtgct gtttatcgga
    45001 atctgtggct tttcttttct agtgggaagt ctgataagtg gttttggaca gttagattat
    45061 ccctacccaa tttatagctt agtgaatcaa gaagtaacta ttgggaaaat acaagatgta
    45121 ttatttcctg gcttgctctt agctttctta gcctttatcg tcattgtgga agttgtgtac
    45181 ttgattgctt actttttcaa gcaaaaaatg cctgtcctct ttctttcact cattgggatt
    45241 gttggcttat tgtttggcat ccaaaccatt cagcctcttc aaaggattgc acatctgatt
    45301 ccctttactt acttgcgttc agtggagatt ttatctggaa gattatctaa gcagattgat
    45361 aatgtcgatc taaattggag catggggatg gtcttacttc cttgcctgat tatccttttg
    45421 ttagtgggga ttctatttat cgaaagatgg ggaagttcac gtaaaaagga agtttttaaa
    45481 gtttagtttt cctataggga agctaaagaa aaactaacat agggagagaa tcaacttggt
    45541 tctctctttt tgattcgaaa accaaaccaa aatacaaaca caaacttttc aaaaaataac
    45601 tttttatctt gacaagagct agaaaacttg gtatcatata aaagttgaga aaagcagaag
    45661 tgagagcttc tcgccttgtg acattaagtt gcctggccct acggatgaaa agtttcgaag
    45721 aaacgctatc ataacgtgcg ggcttgtata tttacgagtc cgctattgtt tttctctaat
    45781 aaaacaaaag aggtgaaaac catagcaaag caagacttat tcatcaatga tgagattcgt
    45841 gtacgtgaag ttcgcttgat tggtcttgag ggagaacagc taggcatcaa gccactcagt
    45901 gaagcgcaag ctttggctga taacgctaat gttgacctag tattgattca accccaagcc
    45961 aaaccgcctg ttgcaaaaat tatggactac ggtaagttca aatttgagta ccagaagaag
    46021 caaaaagaac aacgtaaaaa acaaagcgtt gttactgtga aagaagttcg tctaagtcca
    46081 acaattgaca agggtgactt tgatacaaaa cttcgtaatg cacgtaagtt ccttgaaaaa
    46141 ggaaataaag ttaaggtatc tattcgcttt aagggtcgta tgattaccca taaagagatt
    46201 ggtgcaaaag ttttagccga gtttgctgaa gcaactcaag atattgccat catcgaacaa
    46261 cgtgctaaaa tggatggacg tcaaatgttc atgcaattgg cgccagcgac tgacaaaaaa
    46321 taattgtcag aaagttaaat aaaggagaaa aaatcatgcc aaaacaaaaa acacaccgcg
    46381 catcagctaa acgtttcaaa cgtacaggtt ctggtggact taaacgtttc cgtgcttaca
    46441 cttctcaccg tttccacgga aaaactaaga aacaacgtcg tcatcttcgt aaagcatcta
    46501 tggtgcattc aggagattac aaacgtatca aagcaatgct tactcgcttg aaataatagc
    46561 ttgactgtaa gtaaacaatt ctaggaaata tttggaggaa ataaaacatg gcacgtgtta
    46621 aaggtggcgt tgtatcacgc aaacgtcgta aacgtattct taaattagca aaaggttact
    46681 atggagctaa acacatcttg ttccgtactg caaaagaaca agtaatgaac tcttactact
    46741 atgcataccg tgaccgtcgt cagaaaaaac gtgacttccg caaattgtgg atcactcgta
    46801 tcaatgcggc agctcgtatg aacggacttt catactcaca attgatgcat ggtttgaaat
    46861 tggctgagat cgaagttaac cgtaaaatgc ttgctgactt ggctgttaac gatgcagtag
    46921 ctttcacagc tcttgcagat gcagctaaag caaaacttgg taaataacaa ctgatgagac
    46981 tggaacagga ttgtccagtc tttttaaaaa taaaggagaa aagtatggct tcaaaaatgc
    47041 tacacacttg cttacgagta gaaaatcttg aaaaatcaat tgcattctat caagatgctt
    47101 ttggttttaa agaattgcgt cgcagagatt ttccagacca tgccttcacg attgtctatc
    47161 taggtcttga gggtgatgat tatgagttgg agttgactta taactacgat cacggtccgt
    47221 atgtggttgg tgatgggttt gcccatatcg ccctcagtac acctgatctt gaggcacttc
    47281 atcaagaaca cagtgcaaaa ggctatgaag tgactgagcc aaatggtcta ccaggaacta
    47341 caccaaacta ttactttgtc aaagaccctg atggatataa ggtcgaagtc attcgtgaaa
    47401 aataatttcg tgcaagttaa gtagaatatt cgttttctac ttgacttttt ttagctgaaa
    47461 gagtatacta ataaaaattc aacctttaag gggagtccag agagactcac aaggtgtcag
    47521 ataaaagaat agtgcaattt tctagaggag actttttgag tgtgctctct tgtgttgtac
    47581 gattttaact gaggccttgc actagcaagg tcttttcttt atctggtccc cttaaaattt
    47641 aaggaggaaa agttatgaat cccacatgta agaagcgttt gggtgtcatt cggttggaaa
    47701 ccatgaaggt ggttgcacaa gaggaaatcg cgccagcaat ctttgaatta gttctagaag
    47761 gagaaatggt tgaagccatg cgagcaggcc aatttcttca tctgcgtgta ccggacgatg
    47821 cccatctctt acgtcgtcct atttcaattt cgtctattga caaggcaaac aagcagtgtc
    47881 acctcattta tcggattgag ggagctggga ctgcaatttt ttcaacctta agtcagggag
    47941 acactcttga tgtgatgggg cctcagggaa atggttttga cttgtctgac cttgatgagc
    48001 agaatcaggt tctccttgtt ggtggtggga ttggtgttcc acccttgctt gaggtggcca
    48061 aggaattgca tggacgtgga gtgaaagtag tgacagtcct cggttttgct aataaggatg
    48121 ctgttatttt gaaaacggaa ttggctcagt atggtcaggt ctttgtaacg acagatgatg
    48181 gttcttatgg catcaaggga aatgtttccg ttgttatcaa tgatttagat agtcagtttg
    48241 atgctgttta ctcgtgtggg gctccaggaa tgatgaagta tatcaatcaa acctttgatg
    48301 atcacccaag agcctattta tctctggaat ctcgtatggc ttgtgggatg ggagcttgct
    48361 atgcctgtgt tctaaaagta ccagaaagcg agacggtcag ccaacgcgtc tgtgaagatg
    48421 gtcctgtttt ccgcacagga acagttgtat tataaggaga aaattatgac tacaaatcga
    48481 ttacaagtgt ctctacctgg tttggatttg aaaaatccga ttattccagc atcaggctgt
    48541 tttggctttg gacaagagta tgccaagtac tatgatttag accttttagg ttctattatg
    48601 atcaaggcga caacccttga accacgtttt gggaatccaa ctccaagagt ggcagagacg
    48661 cctgctggta tgctcaatgc aattggcttg caaaatcctg gtttagaggt tgttttggct
    48721 gaaaagctac cttggctgga aagagaatat ccaaatcttc ctattattgc caatgtagct
    48781 ggtttttcaa aacaagagta tgcagctgtt tctcatggga tttccaaggc aactaatgta
    48841 aaagctatcg agctcaatat ttcttgtccc aatgttgacc actgtaatca tggacttttg
    48901 attggtcaag atccagattt ggcttatgat gtggtgaaag cagctgtgga agcctcagaa
    48961 gtgccagttt atgtcaaatt aaccccgagt gtgaccgata tcgttactgt cgcaaaagct
    49021 gcagaagatg cgggagcaag tggcttgacc atgatcaata ctctggttgg aatgcgcttt
    49081 gacctcaaaa ccagaaaacc aatcttggcc aatggaacag gtggaatgtc aggtccagca
    49141 gtctttccag tagccctcaa actcatccgc caagtagccc aaacaacaga cctgcctatc
    49201 attggaatgg ggggagtgga ttcggctgaa gctgccctag aaatgtatct ggctggggca
    49261 tctgctatcg gagttggaac agctaacttt accaatcctt atgcctgtcc tgtcatcatc
    49321 gaaaatttac caaaagtcat ggataaatac ggtattagca gtctggaaga actccgtcag
    49381 gaagtaaaag agtctctgag gtaaactgca atcaatctgt tcttgatttt ttattagttt
    49441 gtaatatgaa tttaggagaa ttttggtaca ataaaataaa taagaacaga ggaagaaggt
    49501 taatgaagaa agtaagattt atttttttag ctctgctatt tttcttagct agtccagagg
    49561 gtgcaatggc tagtgatggt acttggcaag gaaaacagta tctgaaagaa gatggcagtc
    49621 aagcagcgaa tgagtgggtt tttgatactc attatcaatc ttggttctat ataaaagcag
    49681 atgctaacta tgctgaaaat gaatggctaa agcaaggtga cgactatttt tacctcaaat
    49741 ctggtggcta tatggccaaa tcagaatggg tagaagacaa gggagccttt tattatcttg
    49801 accaagatgg aaagatgaaa agaaatgctt gggtaggaac ttcctatgtt ggtgcaacag
    49861 gtgccaaagt aatagaagac tgggtctatg attctcaata cgatgcttgg ttttatatca
    49921 aagcagatgg acagcacgca gagaaagaat ggctccaaat taaagagaag gactattatt
    49981 tcaaatccgg tggttatcta ctgacaagtc agtggattaa tcaagcttat gtgaatgcta
    50041 gtggtgccaa agtacagcaa ggttggcttt ttgacaaaca ataccaatct tggttttaca
    50101 tcaaagaaaa tggaaactat gctgataaag aatggatttt cgagaatggt cactattatt
    50161 atctaaaatc cggtggctac atggcagcca atgaatggat ttgggataag gaatcttggt
    50221 tttacctcaa gtttgatggg aaaatagctg aaaaagaatg ggtctacgat tcttatagtc
    50281 aagcttggta ctacttcaaa tccggtggtt acatgacagc caatgaatgg atttgggata
    50341 aggaatcttg gttttatctc aaatctgatg ggaaaatagc tgaaaaagaa tgggtctacg
    50401 attctcatag tcaagcttgg tactacttca aatctggtgg ttacatgaca gccaatgaat
    50461 ggatttggga taaggaatct tggttttacc tcaagtctga tggcaaaatg gctgaaaaag
    50521 aatgggtcta cgattctcat agtcaagcct ggtactactt caaatctggt ggctacatgg
    50581 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
    50641 aagctacaaa taaaaatgct gcttactatc aagtagtgcc tgtcacagcc aatgtttatg
    50701 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
    50761 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
    50821 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
    50881 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
    50941 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
    51001 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
    51061 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
    51121 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgccctttat ctccttgccc
    51181 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
    51241 ttggcattac agcctatgat acgacccctt acctttctgc caagacattt gatgatgtgg
    51301 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
    51361 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
    51421 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa actaggtggc aaagattagt
    51481 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
    51541 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
    51601 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
    51661 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
    51721 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
    51781 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
    51841 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
    51901 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
    51961 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
    52021 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
    52081 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
    52141 ggagtcagag ccttatcaag cgcaatcatg ataggttggt tggtatagta gttgtctagg
    52201 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
    52261 tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt tttcctgttt tttgagtttg
    52321 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
    52381 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
    52441 aaaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
    52501 ggcttgtttt cttgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
    52561 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
    52621 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
    52681 ttgagagatt ctgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
    52741 ctattttgtg aaaaaccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
    52801 accagtagaa tattactgtg tttccccata atttcaataa tcaaggtagc ctggatatgg
    52861 tctccaatct cgtttttatt ggaaactgta atttccacaa tacggtcatt ttccacttgc
    52921 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
    52981 ggttgagctg gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg
    53041 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
    53101 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
    53161 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
    53221 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
    53281 aaagagaaaa gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
    53341 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gcccaaaaat taggaaaaga
    53401 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcatgaac ttaatctgga
    53461 gtaccgtaac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
    53521 aattgccttt gacgaagagg atttgcttga aaattcagaa ttggcagaga tgatgtctga
    53581 gtttgatgcc tatattgggg aattgttcat ctctagcgat aaggctcatg agcaggccga
    53641 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
    53701 tattaacggc tatgatcact acactccgga agaagaagcg gagatgttcg gtttacaaga
    53761 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgact
    53821 tgatatccag tttagaattt gctttgacag gtatttttac tgctatcaag gaagaacgca
    53881 atatgcgaaa acacgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg
    53941 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtagta gcctttgaga
    54001 ttctcaactc tgctattgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
    54061 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
    54121 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
    54181 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
    54241 aagtcaactt ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
    54301 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
    54361 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
    54421 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
    54481 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
    54541 ttggtggtga ataaaatcga taaggttcat ccagaccagc tcttgtctca gattgatgac
    54601 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
    54661 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
    54721 tctgatcaaa tcacagacca tccagaacgt ttcttggttt cagaaatgct tcgcgagaaa
    54781 gtcttgcacc taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
    54841 aaacgagacg aagagacaga caaggttcac atccgtgcaa ctatcatggt cgagcgcgat
    54901 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
    54961 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
    55021 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
    55081 gaatactaag tagaggtagg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
    55141 cctgaattac ctgaggttga aaccgtttgt cgtggcttag aaaaattgat tataggaaag
    55201 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
    55261 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
    55321 ttttatctga cagacaaggt cttgatttcc catttgcgga tggagggcaa gtatttttac
    55381 tatccagacc aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
    55441 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
    55501 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
    55561 gatttacagg tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
    55621 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
    55681 gctcagattc atccagctag accttcccag actttgacag cagaagaagc gactgccatt
    55741 catgaccaga ccattgctgt tttgggccag gctgttgaaa aaggtggctc caccattcgg
    55801 acttatacca atgcctttgg ggaagatgga agcatgcagg actttcatca ggtctatgat
    55861 aagactggtc aagaatgtgt acgctgtggt accatcattg agaaaattca actaggcgga
    55921 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
    55981 tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
    56041 ttcaagcagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
    56101 ttgaggctct agtacagcac tttgggcaag aaatcattct tgaaaacgga gaactcaatc
    56161 gccctctcct agctagtctc atcttttcaa atcctgaaga gcaaaaatgg tctaatcaaa
    56221 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
    56281 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
    56341 ctgagacttg gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg
    56401 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
    56461 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
    56521 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
    56581 ctgcgtattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
    56641 tttatgccca tcttcgtgga aaatctaggt gtagggagtc agcaagtcgc tttttatgca
    56701 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
    56761 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
    56821 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
    56881 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
    56941 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
    57001 actggtccct ttattggtgg ctttatcgca gaattatttg gcattcgtac agttttctta
    57061 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
    57121 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
    57181 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
    57241 tcgatcggcc ctattttggc tctttatgta cgcgacttag ggcagacaga gaatcttctt
    57301 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gtatgatgag tgcaggagtc
    57361 atgggcaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat
    57421 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
    57481 cgtttcctct ttggcttggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
    57541 aaaatgactc ccaaagccgg catttcgagg gtctttgcct tcaatcaggt attcttttat
    57601 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
    57661 gctgtctttt atgcgacaag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
    57721 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct
    57781 cctcttgtga cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
    57841 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
    57901 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
    57961 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
    58021 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgc agtaaagctc
    58081 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
    58141 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
    58201 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
    58261 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
    58321 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
    58381 gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt cgctttgaag aagatggcag
    58441 tctgaccttg gaagccaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
    58501 taaaaatggt tttggttttg tcagcctaga aggggaagag gacgaccttt ttgtagggaa
    58561 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
    58621 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
    58681 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag cctaagtatg ctggctatat
    58741 tcgttcaaaa aatcagaaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaagtt
    58801 agaaggaaca gaagttctca aggtctttat cgataaatac ccaagcaaga aacatgattt
    58861 ctttgtcgcg agtgttctcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct
    58921 tgaggtcttg gaatcaatgg acattgtatc cgagtttcca gaagctgttg ttaaggaagc
    58981 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
    59041 tgaaattacc tttactattg acggtgcgga tgccaaggac ttggacgatg cagtgcatat
    59101 caaggctctg aaaaatggca atctggagct tggagttcac atcgcagatg tttcttatta
    59161 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
    59221 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
    59281 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
    59341 ggtcaactat accattatac aaacagttat caagaccagt tttcgtatga cctatagcga
    59401 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtacc
    59461 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
    59521 agccctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
    59581 tgatatcgtt cttcggcagc gtggtattgc cgagcggatg attgagtctt ttatgttgat
    59641 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat
    59701 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
    59761 cttgcgcatt tatggaactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg
    59821 tgctgttgag ggagaacctt atgcagatgt attgtccatg atgcttcttc gctctatgca
    59881 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
    59941 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
    60001 ttacggccgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
    60061 ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa
    60121 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
    60181 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
    60241 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
    60301 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
    60361 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
    60421 gaaacagtct agtcatagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
    60481 agacaagaga aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa
    60541 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    60601 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    60661 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    60721 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagtaatg
    60781 ttcatatcgc gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    60841 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    60901 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    60961 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    61021 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    61081 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagctg
    61141 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    61201 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    61261 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    61321 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    61381 acaataccaa tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    61441 aagctttgga tttaggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    61501 ttgatgtgac ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg
    61561 agcaggaaga tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac
    61621 aagagtatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    61681 cagctattat tcaaaatatg caggagaaaa ccagtgttgg tggttacaac cttatcgttt
    61741 gtgccatgga cacggaggat tatccttgct cggttaactt cccattcacc tttaaagaag
    61801 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    61861 atttgcatcg tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag
    61921 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    61981 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    62041 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    62101 gccagctcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    62161 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    62221 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    62281 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    62341 tgcctcagaa agtccttaaa gagcgaagtg agggctatcg tagtcagggt taccaagtac
    62401 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    62461 ttctttattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    62521 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    62581 aggaattttc ctatggtcaa ggtagtttat tggaaatatt gcgtcttccc tataagagac
    62641 aaaaaatatc tcattttaca gtttctgagg acaaggacat ctgtcgctat atccggcaac
    62701 aactttatta tcaaaatctc ttttggatga aagaacaagc agaagcctat caaaagggag
    62761 aaaatatcct gacttatgga ctgaaagaat ggtatccaca aattcgacca atagtgggca
    62821 aatttttcca gattgaacaa gacttgacta gctattatca gcacttttat acctattacc
    62881 aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc agccttttat cagcaatatt
    62941 tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct aatggtatta caaagaaatg
    63001 aaataaatga aaaagataca tgggatctat caacgatcta cccaactgac caggcttggg
    63061 aagaagcctt aaaagattta acagaacaat tggagacagt agcccagtat gaaggccatc
    63121 tcttggatag tgcggataac ctactagaaa tcactgaatt ttctcttgaa atggaacgcc
    63181 agatagagaa gctttacgtt tatgctcata tgaagaatga ccaggataca cgtgaagcta
    63241 agtatcaaga gtactatgcc aaggccatga cactctacag ccagttagac caagcctttt
    63301 cattctatga gcctgaattt atggagatta gcgaaaagca gtatgctgac tttttagaag
    63361 ctcaaccaaa gctgcaggtt tatcaacact attttgacaa gctcttgcaa ggcaaggatc
    63421 acgttctttc acaacgtgaa gaagaattat tggctggagc tggagaaatc tttggttcag
    63481 caagtgaaac cttcgctatc ttggacaatg cggatattgt gttcccttat gtcctagacg
    63541 atgatggtaa agaagttcag ctatctcatg ggatttacac acgtttgatg gagtctaaaa
    63601 aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc gacttacgaa caattccaac
    63661 acacctatgc caaaaccttg caaaccaatg ttaaggtgca aaattaccgt gctaaagttc
    63721 gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt
    63781 atgacaattt ggtagcagca gttcgcaagc atttgccact cttacatcgc tatcttgagc
    63841 ttcgttcaaa aatcttgggg atttcagatc tcaagatgta cgatgtctac acaccgcttt
    63901 catctgttga atacagtttt acctaccaag aagccttgaa aaaagcagaa gatgctttgg
    63961 cagtcttggg tgaggattac ttgagccgtg tcaaacgtgc cttcagcgag cgttggattg
    64021 atgtttacga aaatcaaggc aagcgttcag gtgcctactc tggtggttct tacgatacca
    64081 atgcctttat gcttctcaac tggcaggaca atctggacaa tctctttact cttgttcatg
    64141 aaacaggtca cagtatgcat tcaagctata ctcgtgaaac tcagccttat gtttacggag
    64201 attactctat ctttttggct gagattgcct caactaccaa tgaaaatatc ttgacggaga
    64261 aattattgga agaagtggaa gacgacgcaa cacgctttgc tattctcaat aacttcctag
    64321 atggtttccg tggaacagtt ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc
    64381 accaagcaga tcaaaatggg gaggtcttga caagcgattt cctaaataaa ctctacgtag
    64441 acttgaacca agagtattat ggtttgagta aggaagacaa tcctgaaatc caatacgagt
    64501 gggctcgcat tccacacttc tactataact actatgtata tcaatattca actggatttg
    64561 cggccgcctc agccttggct gaaaaaattg tccatggtag tcaagaagac cgtgaccgct
    64621 atatcgacta cctcaaggca ggtaagtcgg actatccact taatgtcatg agaaaagctg
    64681 gtgttgatat ggagaaggaa gactacctca acgatgcctt tgcagtcttt gaacgccgtt
    64741 taaatgagtt tgaagccctt gttgaaaaat taggattggc ataaaatggt tgaatcgtat
    64801 agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg
    64861 atgcgtcagc gtcaaaagca ggtcacaggt tccttgaaag aattggaaga ctttgcccgc
    64921 aaggaaaata ttcctattat tccccatgaa acggttgctt atttccgttt tcttatggaa
    64981 accatgcagc ctaaaaatat tctggaaatt gggacggcta tcggtttttc agctctcttg
    65041 atggctgaac atgcgccaaa tgctaagatt acaactattg atcgtaatcc agaaatgatt
    65101 ggttttgcca aggaaaattt tgcccagttt gacagtcgca agcaaatcac tctcctagag
    65161 ggagatgcgg tggatgtctt atctacactg acagagtctt atgatttcgt ctttatggat
    65221 tctgccaagt ctaaatacat cgtctttctg ccagaaatcc tcaaacattt ggaagttggt
    65281 ggtgtggttg tcttggatga tatttttcaa ggtggtgatg ttgccaagga tattatggaa
    65341 gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa aattatttga tgcaacctta
    65401 gacaatccag aactcaccgc aacattagtg cctttaggag atggtattct catgcttcgt
    65461 aaaaatgtag cagatgttca actgtctgaa agcgaatgat tttcagaaaa atttaagaaa
    65521 aaatagtaaa atagatagag taacacttat ctcaaaggag tagacatgaa gaaaaaatta
    65581 ttggcaggtg ccatcacact attatcagta gcaactttag cagcttgttc gaaagggtca
    65641 gaaggggcag accttatcag catgaaaggg gatgtcatca cagaacatca attttatgag
    65701 caagtgaaaa acaacccttc agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt
    65761 tttgaaaaac aatatggctc agagcttgat gataaagagg ttgatgatac tattgccgaa
    65821 gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt cacaagcagg tatgactctt
    65881 gaaacacgta aagctcaaat tcgtacaagt aaattagttg agttggcagt taagaaggta
    65941 gcagaagctg aattgacaga tgaagcctat aagaaagcct ttgatgagta cactccagat
    66001 gtaacggctc aaatcatccg tcttaataat gaagataagg ccaaagaagt tctcgaaaaa
    66061 gccaaggcag aaggtgctga ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa
    66121 acaaaagaaa atggtggaga aattaccttt gattctgctt caacagaagt acctgagcaa
    66181 gtcaaaaaag ccgctttcgc tttagatgtg gatggtgttt ctgatgtgat tacagcaact
    66241 ggcacacaag cctacagtag ccaatattac attgtaaaac tcactaagaa aacagaaaaa
    66301 tcatctaata ttgatgacta caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa
    66361 aatgattcaa catttgttca aagcattatc ggaaaagaat tgcaagcagc caatatcaag
    66421 gttaaggacc aagccttcca aaatatcttt acccaatata tcggtggtgg agattcaagc
    66481 tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga gtcagggaaa aaactcgact
    66541 tcaggaaaaa atgaagcaaa cattcccaca ataaaacgca tagtacaagg tttgtactga
    66601 ccccaaaagt tagacaatta atttatctga aggatttagt tctgtattgc acagggctaa
    66661 gtccttttag ttttacctta attctcttat tgttgtaata atcaatatag tctataatgg
    66721 cttgttccaa ttgattaagt gatttaaatg ttttctcata gccataaaac atttcggatt
    66781 ttaaaatgcc aaagaaagat tccatcctac cgttgtcttg gctgtttcct ttgcgtgaca
    66841 tagatgcttg aattccctta ctctctagga agcgatgata agaatcgtgt tgatattgcc
    66901 agccttggtc actatggaga atcgtattct cgtagtgctt ctctttgaat gcctgttcca
    66961 acattaacga tcaatcaatt taatcatgta cctaatatta gaattgttta tcccaaattt
    67021 atttgaaagc ttctctaagc tatatccttg ttttctaagt tcatagatct gaactttatc
    67081 atcataagtt aatttcataa taaaaacacc ccaaaagtta gattttttct gtctaacttt
    67141 tggggtgtag ttcatgtaca cctgatatga tgcgtttttt gaattttata gactgctcgt
    67201 ttaaactcta tttacctcgt acattccgga gcgagacgga atattagcca catacaaaat
    67261 gagtactatt aggattttat tttcgtgtac aatttcagct attcttgtta taatcagcct
    67321 ataggaatca aggaggggac tcttatggct gtttttgtgt ctttggatgg aattgtggta
    67381 gaagtacttg atgtcttttc ttcttttaat ggggatagtg agtttttctt gtgtaaacgt
    67441 cttaaagaca agagtcagtt tgttatggaa cgctctcagt tcgaggagat gttccaactt
    67501 caaagtagtc gcttgacgac gcaagaaaaa ttacaattgt ttacctccgt gtttgctgga
    67561 cgttatgatg tttatgctaa gaattttatc aatgaacaag ggaaaattca gtattttcct
    67621 tcctatgatt atggttggaa gcagttgcca cctgaaaaac ggagtttcca gacattgacg
    67681 aactccgttt tgaaatctca ttttcgtggg gaggcagcta tcggtatctt tcctatgcac
    67741 ttagatgata gctgttattt tttggtactg gatttggatg aaggagattg gaaagaagct
    67801 ggtttaacca ttcgaagaat agcaagggaa cgccagatgg aagcccattt agagatttct
    67861 cgttcgggtt acggactcca tatttggttc ttctttgagg aagcgattct gagtcgaaag
    67921 gctcgcctgt ttggaaagaa actattagaa ttggctatgc aggaaagtat gcaactgtcc
    67981 tttgattctt ttgatggcat gtttccaaat caggatgttc ttcctaaagg tggatttgat
    68041 aatttaattt cccttccttt tcaaggagaa gcttatcatc aagggcgaac ggtctttgtg
    68101 gatgaacatt ttcagcctta tgaagatcaa tggaggtatc tacaagaaat tcagaggatt
    68161 tcaactgcta aagtggcact gttaatccaa gaggagttag gcaagcaaga attggataag
    68221 gagttgaagg tcgttttatc caatatgatc caacttgaaa aatcgtctgt gacatccaag
    68281 gcactttttt tcttgaaaaa tatggcttcc ttttctaatc ccgaatttta tagtagattg
    68341 aaactagaat agtatacctc tgcttctaaa acattgttag aaatcgattt gactttcctg
    68401 atcgatttgt cctgttatta tttcatttta ttatatttaa agcaggctat gcgacagcca
    68461 acctatcaaa ttcctgagcg aatgtattta tttggagaat ccgattatta tttatggctg
    68521 ccaagaggct tgttatatcc attgcaagat aaatttaagc aggtagttgt ggaggatagg
    68581 agaaaagtac aaaggtctat tagagtagca tttaagggag agcttacttt ggagcaagaa
    68641 ttagccctgt cagatatgaa ttctaaagaa aatggtttac ttcatgcggg acaggttttg
    68701 gaaagatcgt tttaggtgct gctcttatct ctgaacgtaa gacaaaaacc attatcctag
    68761 ttcataatag acaactctta gaccaatgac tggatcgttt aaagtgtttt ttgactttcg
    68821 aagaggcaga agctacccgt tatacaccat caggtcgtga aagggtaata ggctatgtcg
    68881 ggcagtacgg tggggctaag aaatgactga gtaaactggt tgatgttgtt atgattcaat
    68941 ctctatttaa gttggaaaat agtcaaagtc ttttggatga gtatgagatg atgattgtgg
    69001 atgagtgtca tcatatctct gccttgatgt ttgaaaaagt tgttgctcag tttagaggga
    69061 agtatcttta cggtttgacg gctacgcctg agcgtaagaa tggtcatgaa cctattgttt
    69121 ttcagagaaa ttgaaaagac caaagcaagt aattttatac agctcagtga ttggattgct
    69181 acagactcag cgaggaatca gttgattctc aaggatattc tagcccaagt ggcagaagga
    69241 cggaatatct tggttttagt taatcgaatt caacagatag atgtctttga aaagttattg
    69301 aaagagaaag aggttgatga ctgttacatt attagcggaa aaaccaaagt ccgagaaaga
    69361 gaacgagttt actggagacg ttagaacagt tagataaagg gtttgttttg ttgtctactg
    69421 gaaaatacat tggcgaaggt tttgacttac ctcagttgga cacgcttatc ttggcagcac
    69481 ccttttcttg gaaaaataat ttgattcagt actcaggtcg gattcataga aactacaagg
    69541 ataagtcttt ggtgcggatt ttcgattatg tggatattca tgttccttat ttagaaaaga
    69601 tgtttcagaa acgacaagta gcttatcgaa agatggatta tcgtgccatt gagggtgagg
    69661 agaaacaatt cgtttatgtt gatagtagat atgagaaggt gttgagagag gacttagcag
    69721 gggaaagaca ggaatgtctg cttattttac cttatgtgca ccagacaaaa ctgatgaatt
    69781 ttctaaaaga atttaggatt agtcaaattg agatatgtat accagagacg gttgcaaata
    69841 aagcatggct agaccagttg aagagccaga aaattaaagt gtcttttact caatcaaaaa
    69901 tagtaacgcc tattcttttg gtgaataaga ctattgtttg gtatggtgca atgccattat
    69961 tagggaaggt agatgagatg accatattac gtttggaatc agctagtata gtttctgaac
    70021 tagtggcagg tttacgatag agaaaatttt taaaaatttc tatgtatgat tttcatttct
    70081 ttagtgagac tgttgccatt atcacattcg aatcacacaa aataaaaaaa tttttataag
    70141 tacttgacaa atagattgaa atatcataaa ataaaaacgg ttacagagtt attaattatt
    70201 taagcttcat gtcaccatta aaaattgaaa taaaaggatg ttatcactaa tacaagtgag
    70261 caggaaccta tttaatcaca tcagaagaag tttcttgatg ttttttaagt aggttccttt
    70321 tattttaaaa gggaaatttt atgatcataa aacgaatact aaaccacaat gccgtaattg
    70381 cgcaaagtaa aaaagatatc gatattcttc tttttggaag gggaatagct tttggaagaa
    70441 aaattggaga taaagtaaat ccaattgata ttgagaaaag tttttttctc aaaaatagag
    70501 ataatatgac ccgttttaca gagatgttta ttaacgttcc tttggagttg gtgtacatca
    70561 ccgaaaaaat aattaatcta ggtaaaataa cattaggtaa taattttgat gagattatct
    70621 atataaatct aacggatcat atttcttcga gtatagaacg ttataaagaa ggagttatta
    70681 tttcgaatcc cctacgctgg gaaatatcga aatattataa agaagaattt gagcttggga
    70741 aaagggcttt acaaataata aaaaaagagt taggtattga acttccaatt gacgaagctg
    70801 cattcatagc gctacatttt gttaatgcta atttagaaaa taattttcaa gagtcgtata
    70861 aaatcactga aataattatg ggaattgaga aaatcattca agatttctat tgtactgagt
    70921 ttaaccaaga ttctattgat tattatagat tcataactca tataaaatta tttgcccatc
    70981 gcttggttga aaatacaact tattgtgacg atgatgatga agacttgtta gcattaatga
    71041 aaaataaata tcctagagaa tatgaatgtg gtgaacaggt ggcaatgttt atacaaactg
    71101 agtacaatta tttgctgact tctagtgaat tagtttattt gatggctcat attcgtcgct
    71161 taacaaaaaa tttagattaa tagaatagga gaataccatg agttataaag ataaggtaca
    71221 aaaaatcctc gatgtaattg gaggtgaaaa aaatgtcaat agagttaccc attgtgtaac
    71281 acgtttaaga ttagaattaa aagatgaaaa tttagtcaat gatgatgatg tgaagaagat
    71341 accaggtgta ataggtatta tgaaaaagaa tggacaatat caaattatac ttggtaatga
    71401 tgtagctaat tattataaag aattcgttaa acttggcaat tttgaatccg attcagttgt
    71461 tcaagggcac aaagggaata ttttagaaag aatcattgag tatatcgctg gttccatgac
    71521 tccaatcatt ccagcaatgt tagggggagg tatgctgaaa gtcttggtaa ttattttacc
    71581 aatgcttggt atattgcaat cagattctca gactattgct tttttgacat tttttgggga
    71641 tgctccatat tatttcttac cgctgttatt agcttattct gcatcacaaa aattaaaagt
    71701 aacatctaca ttagctatgt ctgtagcagg tgtacttctc catccaaatt ttgttcaaat
    71761 ggtgcaatca gggaatcctc ttagtttatt tggtgtacct gtgataccag ctagttatgg
    71821 ttcgtcagtc gttccaattc ttattatggt ttggttgatg aaatatattg aaaaaatgat
    71881 tgctaaatta acaccagctg ttactaagag ttttttgcaa cctacgctag tattattagt
    71941 atcaagctgt attgccttag ttgtagtcgg gcctattgga gtaattgttg gtgaaggatt
    72001 atcaaatcta gttgggcaaa tgtatgatgt agctggatgg cttacattag ctattcttgg
    72061 tgctattatg ccatttattg ttatgactgg aatgcattgg gcttttgcac ctattttttt
    72121 ggcggcatct attgctactc cagacgtatt aattcttcca gcaatgttag ggtcaaactt
    72181 agctcaaggg gctgcttcga tggctgttgc attaaagagt aaaaataata atacaaaaca
    72241 aattgctttt gcagcaggtt tctcagcctt acttgcaggg attaccgaac ctgcattata
    72301 tggtgtgact ttaaaatata aaaaaccgct ttatgcagct atgattggtg gtggattagc
    72361 gggattattt gcaggtctta ctagtgttaa agcgtatcta tttgctgtcc catctttgat
    72421 agcgttgcct caatttattt attctgatgt accatcaaat attgtaaatg ctttaattgt
    72481 ggcggttatt tcggttgtta ttacctttgt attagcttat atatttggaa tcgatgaaga
    72541 agagagttct agcaatttag aagttaaagc tggagtttca aataaaaaaa tgatattttc
    72601 tcctatatca ggagaaatca ttccgttaag cgatgtccag gataaaacat tttcagataa
    72661 actaattgga gacggagtag cgattattcc aagtgaaggt aaggtttatg caccatttga
    72721 tgggaaaatt acaaatattt ttccgactaa gcacgcaatt ggattgaaga gtgatgaggg
    72781 tgttgagtta ctaattcata ttggattaga tactgttgag ctaaaaggtc aaggttttat
    72841 tagtcatgta gaagaaggag acagagtttt caaaaatcag ttgatttttg aaatggactt
    72901 gaatttaatc aagactaaag gctacgaaac agttacacca gtaattgtaa cgaataccaa
    72961 tgattttcta gatgtattag tattacctaa taatcagaca atcgagcatt ctaaggaatt
    73021 actggtaata ttataatgga ggaaagttat gaccattttt ccagatgatt ttctttgggg
    73081 tggagctgtt gcagctaatc aagtagaggg agcatataat gaagatggta agggcttatc
    73141 agttcaggat gtgttaccca aaggtggatt aggagaagca acagaaaatc ctacagaaga
    73201 taacttaaaa ttgataggta ttgattttta tcataaatat aaggaagata tatccttgtt
    73261 ttctgaaatg ggctttaatg tttttcgtac ttctattgca tggagtagaa tttttccaaa
    73321 aggagatgag gaagaaccta acgaagctgg gttgaaatat tatgatgaat tgtttgatga
    73381 actacatgct cacgggatag aaccacttgt aactctttca cactatgaga ctccattata
    73441 tttagcaaga aaatatcatg gatggattga taggagaatg attcattttt atgaaaaatt
    73501 tgctcgaaca gttttagaaa ggtataaaga taaagttaaa tattggctta catttaacga
    73561 agtaaactct gttttggaat taccgtttac tagtggagga atagatatac ctaaggagaa
    73621 tctttcgaaa caagaattat atcaagctat acatcatgaa ttagtcgcct cgagtttggt
    73681 tacaaaaatt gctcgtgaga ttaattcaga gtttaaggtg gggtgtatgg tattagctat
    73741 gccagcttat ccaatgactc caaatccaaa agatgtatgg gcgactcatg agtatgagaa
    73801 tctaaattat ctattttcag atgtgcatgt tagaggttat tatccgaatt atgcaaaaag
    73861 atattttaag gaaaatgaca ttaacataga gtttgcagct gaagatgcag agttattaaa
    73921 aaattatact gtagattttt tatcctttag ctattacatg agtgtgactc aatctgctct
    73981 tccaacacag tataattcag gagaagggaa tattattggt ggtttagtaa atccttattt
    74041 agagtcttct gagtggggat ggcaaattga tccaattgga ctacgtataa ttttaaatag
    74101 atattatgac cgttatcaaa ttccattatt tatagtggaa aacggattag gtgctaaaga
    74161 tcaactaata aaagatgaat ttaataactt aacagtccaa gatgattata gaattcagta
    74221 tatgaaagaa catttattgc aagtagctga agctctacaa gatggtgtgg aaattatggg
    74281 ctatacgtct tggggatgta ttgactgcgt ttctatgtcc actgcacagc tttctaagag
    74341 gtacggtctc atttatgttg atcgaaatga tgatggaaat ggcacattca atcgatataa
    74401 gaaaatgtcc tttacttggt ataaaggagt gattgaatca aatggagaat ccttattcaa
    74461 atagtttttt attgatgact agctattatc acggttaagg tggcatttca ttaaatatgg
    74521 aataaagaag tttggaagac attaaattct aaacttcttt attttatagg ggagtgtcaa
    74581 ttaatttaat tttgttacaa aaattataaa tagtt
//
LOCUS       DAVMBH010000006        71590 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVMBH010000006 DAVMBH010000000
VERSION     DAVMBH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 71590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.006"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            119..2011
                     /gene="pepO"
                     /locus_tag="VYP30_000446"
     CDS             119..2011
                     /gene="pepO"
                     /locus_tag="VYP30_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1807495.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2134..2763)
                     /locus_tag="VYP30_000447"
     CDS             complement(2134..2763)
                     /locus_tag="VYP30_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1807496.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(3103..3345)
                     /locus_tag="VYP30_000448"
     CDS             complement(3103..3345)
                     /locus_tag="VYP30_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807497.1"
                     /translation="MMRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            3756..5978
                     /locus_tag="VYP30_000449"
     CDS             3756..5978
                     /locus_tag="VYP30_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1807498.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6008..6451
                     /locus_tag="VYP30_000450"
     CDS             6008..6451
                     /locus_tag="VYP30_000450"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1807499.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6490..6904)
                     /locus_tag="VYP30_000451"
                     /pseudo
     CDS             complement(6490..6904)
                     /locus_tag="VYP30_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6923..7336)
                     /locus_tag="VYP30_000452"
     CDS             complement(6923..7336)
                     /locus_tag="VYP30_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807500.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7438..8115)
                     /locus_tag="VYP30_000453"
     CDS             complement(7438..8115)
                     /locus_tag="VYP30_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1807501.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTLLFGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYEGKMDLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            complement(8314..8964)
                     /locus_tag="VYP30_000454"
     CDS             complement(8314..8964)
                     /locus_tag="VYP30_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1807502.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     NFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            9076..9918
                     /locus_tag="VYP30_000455"
     CDS             9076..9918
                     /locus_tag="VYP30_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1807503.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9994..10431
                     /locus_tag="VYP30_000456"
     CDS             9994..10431
                     /locus_tag="VYP30_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1807504.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10499..10801
                     /locus_tag="VYP30_000457"
     CDS             10499..10801
                     /locus_tag="VYP30_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807505.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10892..11965)
                     /locus_tag="VYP30_000458"
     CDS             complement(10892..11965)
                     /locus_tag="VYP30_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1807506.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVNLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            12121..12798
                     /locus_tag="VYP30_000459"
     CDS             12121..12798
                     /locus_tag="VYP30_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1807507.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12791..13765
                     /locus_tag="VYP30_000460"
     CDS             12791..13765
                     /locus_tag="VYP30_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1807508.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13814..15757)
                     /gene="thrS"
                     /locus_tag="VYP30_000461"
     CDS             complement(13814..15757)
                     /gene="thrS"
                     /locus_tag="VYP30_000461"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1807509.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15815..15991)
                     /locus_tag="VYP30_000462"
     CDS             complement(15815..15991)
                     /locus_tag="VYP30_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1807510.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            complement(15998..16138)
                     /locus_tag="VYP30_000463"
     CDS             complement(15998..16138)
                     /locus_tag="VYP30_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1807511.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            17008..17637
                     /locus_tag="VYP30_000464"
     CDS             17008..17637
                     /locus_tag="VYP30_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1807512.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKEHISLLEK"
     gene            17778..18047
                     /gene="rpsO"
                     /locus_tag="VYP30_000465"
     CDS             17778..18047
                     /gene="rpsO"
                     /locus_tag="VYP30_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1807513.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18862..19476
                     /locus_tag="VYP30_000466"
     CDS             18862..19476
                     /locus_tag="VYP30_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1807514.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19768..20517)
                     /locus_tag="VYP30_000467"
     CDS             complement(19768..20517)
                     /locus_tag="VYP30_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1807515.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20650..22986
                     /locus_tag="VYP30_000468"
     CDS             20650..22986
                     /locus_tag="VYP30_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1807516.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23088..23765
                     /locus_tag="VYP30_000469"
     CDS             23088..23765
                     /locus_tag="VYP30_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1807517.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAERILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23752..24549
                     /locus_tag="VYP30_000470"
     CDS             23752..24549
                     /locus_tag="VYP30_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1807518.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSCGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQEDDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIATLLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24566..25669
                     /locus_tag="VYP30_000471"
     CDS             24566..25669
                     /locus_tag="VYP30_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1807519.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVAVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25970..26989
                     /gene="galE"
                     /locus_tag="VYP30_000472"
     CDS             25970..26989
                     /gene="galE"
                     /locus_tag="VYP30_000472"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1807520.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26991..27956
                     /locus_tag="VYP30_000473"
     CDS             26991..27956
                     /locus_tag="VYP30_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1807521.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(28007..28213)
                     /locus_tag="VYP30_000474"
     CDS             complement(28007..28213)
                     /locus_tag="VYP30_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1807522.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28265..28741
                     /locus_tag="VYP30_000475"
     CDS             28265..28741
                     /locus_tag="VYP30_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1807523.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28750..29421
                     /locus_tag="VYP30_000476"
     CDS             28750..29421
                     /locus_tag="VYP30_000476"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1807524.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29552..29890
                     /locus_tag="VYP30_000477"
     CDS             29552..29890
                     /locus_tag="VYP30_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1807525.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29893..30522
                     /locus_tag="VYP30_000478"
     CDS             29893..30522
                     /locus_tag="VYP30_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1807526.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30763..31914
                     /locus_tag="VYP30_000479"
     CDS             30763..31914
                     /locus_tag="VYP30_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1807527.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32226..32975
                     /gene="truA"
                     /locus_tag="VYP30_000480"
     CDS             32226..32975
                     /gene="truA"
                     /locus_tag="VYP30_000480"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1807528.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            32965..33738
                     /locus_tag="VYP30_000481"
     CDS             32965..33738
                     /locus_tag="VYP30_000481"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1807529.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33716..34177
                     /locus_tag="VYP30_000482"
     CDS             33716..34177
                     /locus_tag="VYP30_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1807530.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34404..35741
                     /locus_tag="VYP30_000483"
                     /pseudo
     CDS             34404..35741
                     /locus_tag="VYP30_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(35869..36072)
                     /locus_tag="VYP30_000484"
     CDS             complement(35869..36072)
                     /locus_tag="VYP30_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807531.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(36065..37147)
                     /locus_tag="VYP30_000485"
     CDS             complement(36065..37147)
                     /locus_tag="VYP30_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1807532.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(37273..38055)
                     /locus_tag="VYP30_000486"
     CDS             complement(37273..38055)
                     /locus_tag="VYP30_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1807533.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(38055..39398)
                     /locus_tag="VYP30_000487"
     CDS             complement(38055..39398)
                     /locus_tag="VYP30_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1807534.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILEAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(39497..40813)
                     /locus_tag="VYP30_000488"
     CDS             complement(39497..40813)
                     /locus_tag="VYP30_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1807535.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            41006..42232
                     /locus_tag="VYP30_000489"
     CDS             41006..42232
                     /locus_tag="VYP30_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1807536.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            42431..44005
                     /locus_tag="VYP30_000490"
     CDS             42431..44005
                     /locus_tag="VYP30_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1807537.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            44270..45058
                     /gene="codY"
                     /locus_tag="VYP30_000491"
     CDS             44270..45058
                     /gene="codY"
                     /locus_tag="VYP30_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1807538.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            45058..45633
                     /locus_tag="VYP30_000492"
     CDS             45058..45633
                     /locus_tag="VYP30_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1807539.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            45714..45799
                     /locus_tag="VYP30_000493"
     tRNA            45714..45799
                     /locus_tag="VYP30_000493"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45748..45750,aa:Leu,seq:aag)
     gene            46072..47202
                     /gene="ugpC"
                     /locus_tag="VYP30_000494"
     CDS             46072..47202
                     /gene="ugpC"
                     /locus_tag="VYP30_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1807540.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(47349..47495)
                     /locus_tag="VYP30_000495"
     CDS             complement(47349..47495)
                     /locus_tag="VYP30_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807541.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            47703..48461
                     /locus_tag="VYP30_000496"
     CDS             47703..48461
                     /locus_tag="VYP30_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1807542.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            48549..49061
                     /locus_tag="VYP30_000497"
     CDS             48549..49061
                     /locus_tag="VYP30_000497"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1807543.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKTTIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            49243..50187
                     /locus_tag="VYP30_000498"
     CDS             49243..50187
                     /locus_tag="VYP30_000498"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1807544.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYRYL"
     gene            50196..50873
                     /locus_tag="VYP30_000499"
     CDS             50196..50873
                     /locus_tag="VYP30_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1807545.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEISPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            50971..51729
                     /locus_tag="VYP30_000500"
     CDS             50971..51729
                     /locus_tag="VYP30_000500"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1807546.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            51767..53271
                     /gene="lytC"
                     /locus_tag="VYP30_000501"
                     /pseudo
     CDS             51767..53271
                     /gene="lytC"
                     /locus_tag="VYP30_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            53767..54285
                     /locus_tag="VYP30_000502"
     CDS             53767..54285
                     /locus_tag="VYP30_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1807547.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            54415..54921
                     /locus_tag="VYP30_000503"
     CDS             54415..54921
                     /locus_tag="VYP30_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1807548.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            54921..55091
                     /locus_tag="VYP30_000504"
     CDS             54921..55091
                     /locus_tag="VYP30_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807549.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            55123..56355
                     /gene="clpX"
                     /locus_tag="VYP30_000505"
     CDS             55123..56355
                     /gene="clpX"
                     /locus_tag="VYP30_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1807550.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            56364..56951
                     /locus_tag="VYP30_000506"
     CDS             56364..56951
                     /locus_tag="VYP30_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1807551.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            56962..57342
                     /locus_tag="VYP30_000507"
     CDS             56962..57342
                     /locus_tag="VYP30_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1807552.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            57394..58284
                     /gene="rapZ"
                     /locus_tag="VYP30_000508"
     CDS             57394..58284
                     /gene="rapZ"
                     /locus_tag="VYP30_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1807553.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            58281..59258
                     /locus_tag="VYP30_000509"
     CDS             58281..59258
                     /locus_tag="VYP30_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1807554.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIHPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            59255..60166
                     /gene="whiA"
                     /locus_tag="VYP30_000510"
     CDS             59255..60166
                     /gene="whiA"
                     /locus_tag="VYP30_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1807555.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(60200..61165)
                     /locus_tag="VYP30_000511"
     CDS             complement(60200..61165)
                     /locus_tag="VYP30_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1807556.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            61301..62158
                     /locus_tag="VYP30_000512"
     CDS             61301..62158
                     /locus_tag="VYP30_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1807557.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYTSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            62145..62924
                     /locus_tag="VYP30_000513"
     CDS             62145..62924
                     /locus_tag="VYP30_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1807558.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            62948..64300
                     /locus_tag="VYP30_000514"
     CDS             62948..64300
                     /locus_tag="VYP30_000514"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1807559.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLT
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            64374..64748
                     /locus_tag="VYP30_000515"
     CDS             64374..64748
                     /locus_tag="VYP30_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1807560.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            64750..65598
                     /locus_tag="VYP30_000516"
     CDS             64750..65598
                     /locus_tag="VYP30_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1807561.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVENVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            65875..66642
                     /locus_tag="VYP30_000517"
     CDS             65875..66642
                     /locus_tag="VYP30_000517"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1807562.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVFDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            66654..67838
                     /locus_tag="VYP30_000518"
     CDS             66654..67838
                     /locus_tag="VYP30_000518"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1807563.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQNKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            67835..69706
                     /locus_tag="VYP30_000519"
     CDS             67835..69706
                     /locus_tag="VYP30_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1807564.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKREVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(69849..71033)
                     /gene="mntE"
                     /locus_tag="VYP30_000520"
     CDS             complement(69849..71033)
                     /gene="mntE"
                     /locus_tag="VYP30_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1807565.1"
                     /translation="MKQSISNLKLAERGAIISISTYLLLSAAKLATGHLLHSSSLVAD
                     GFNNISDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFLVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEDRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKETYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            71203..>71590
                     /locus_tag="VYP30_000521"
     CDS             71203..>71590
                     /locus_tag="VYP30_000521"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807566.1"
                     /translation="MKNEKITAFSFSLFLGIITWFTLATSVRKGLPLLDASIFEYFGY
                     AMSHGQRMYLDLFDHKGPVIFLINYLGYSIGASLGIKILYLVSLIVFFYIGYYISRLF
                     TGIRNSCVVLVITFIIFESFFEGGWGL"
BASE COUNT        20972 a        13310 c        16343 g        20965 t
ORIGIN      
        1 ttttatcatg gaaaggtttt ttataatagc taaaaaataa tagttaaatg gttattaatt
       61 gcattcccta gtgatttttg ttaagataaa tgcaaataca aatgaaagcg agaacaagat
      121 gacacgttat caagatgatt tttatgatgc tatcaatgga gaatggcaac agacagctga
      181 aatcccagca gataagtctc aaacaggagg ttttgttgat ttagaccagg aaattgaaga
      241 cctgatgctg gcgacaacag acaagtggtt agcaggtgaa gaagtgcctg aggatgctat
      301 cttggaaaac tttgtcaaat accaccgcct agttcgtgat tttgacaaga gagaagctga
      361 cggtatcaca cctgtcttac cactccttaa agaattccaa gaattggaga cttttgcgga
      421 ttttacagct aaactagcag agtttgagct tgcaggaaaa ccaaacttcc ttccttttgg
      481 tgtatcgcca gactttatgg atgctagaat caatgttcta tgggctagcg ctccaagcac
      541 aatcttgcca gatacgacct actatgcaga agaacatcct cagcgcgaag aactcttgac
      601 tctttggaaa gaaagcagcg caaatctcct caaggcttat gatttctctg atgaagaaat
      661 tgaagacttg ctagaaaaaa gacttgaatt ggaccgccga gttgcggcag tggtgctctc
      721 taatgaagaa agttcagaat atgctaaact ctatcatcca tattcttacg aagatttcaa
      781 gaaattcgcg cctgccctac ctttggatga cttcttcaaa gcagttattg ggcaattacc
      841 agacaaggtt attgtagacg aggaacgttt ctggcaagca gcagagcaat tctacagtga
      901 ggaagcctgg tctctcctta aagcaacctt gattttgagt gttgtcaatc tttcaaccag
      961 ctatttaaca gaggatatcc gtgttttgtc tggtgcctac agccgtgccc tttctggagt
     1021 tccagaggca aaagataagg tcaaagcagc ttatcatcta gcacaggaac ctttcaagca
     1081 agccctgggg ctttggtacg cccgtgagaa gttctctcca gaagccaagg cggatgtgga
     1141 gaaaaaagtg gcaaccatga ttgatgtcta taaggagcgt ctgcttaaga atgactggct
     1201 cactccagaa acctgtaaac aggctatcgt gaagctcaat gtgatcaaac cttatattgg
     1261 ctatccagaa gaattgcctg cacgttacaa ggataaggta gtgaatgaaa ctgccagtct
     1321 ttttgagaat gctctagcct ttgcgcgtgt ggaaatcaag cacagttgga gtaagtggaa
     1381 ccagcctgta gactataagg aatggggcat gcctgctcat atggtcaatg cctactacaa
     1441 tcctcagaag aacctgattg tctttccagc ggccatttta caggcgcctt tctatgactt
     1501 gcatcagtca tcttctgcta actacggtgg tattggggca gtgattgccc atgaaatttc
     1561 ccacgccttt gatactaacg gggcttcctt tgacgaaaat ggtagcctca aggattggtg
     1621 gacagagagc gactatgctg ccttcaagga gaaaacacaa aaagtcattg accaatttga
     1681 tggacaggat tcttatggag caaccattaa cggtaaattg actgtatcag aaaacgtggc
     1741 tgacttggga ggaatcgcag cagcgcttga agcagctaag agagaagcag acttctcagc
     1801 agaagagttc ttctacaact tcggtcgcat ctggcgcatg aaaggtcgac cagaatttat
     1861 gaaacttttg gctagcgtcg atgtgcacgc accagccaaa ctccgtgtca atgtgcaagt
     1921 accaaacttc gacgatttct ttacaaccta tgatgtcaaa gaaggagacg gaatgtggcg
     1981 ttcaccagag gagcgcgtga ttatttggta atacaaaaaa tctagtcatc agaaaaaagg
     2041 catccaatca cgtgtgaaaa ccttgatagg atgccttttg taatagaaag atttgctgga
     2101 tagtttactt aaatttcgat tgtcatcatc ttgctagaaa aagggattga aggccttttc
     2161 gtgagcgata gtagtagctg gaccatgtcc tggatagaca tcgtagtttg gtagggtgaa
     2221 gagttgggtc tggatactat gaaggagttg ctccatgcta ccagtcggaa ggtcggtccg
     2281 tccgatagtt tcgcggaata gagcatctcc cgtcaagact aggtgagcat caggaaagac
     2341 tagggaaaca ccaccgatag agtgccctgg ggtcggtaga accttaaaac gaaattcctc
     2401 tagttggtat tcttcgtgaa agacaaaggt gtgttctgca ggttttgtga ccacatctgc
     2461 catatcatcg tggcgaggga gaccggagag attatcgaca ggagtgtaga gccagctggc
     2521 ttcgctctct gcgatataga caggaggatt gccaaacgtc tcgcgaacca agtccagact
     2581 catgatatgg tcataatggg cgtgggtcaa gagaatagca cagatcggtt tgttgatctt
     2641 ctcgattgtc tgacgaatgg cttcccaatg actaccagga tcgacgacga tgaggtgctt
     2701 ttcgccttct agataatagg tattttcata ggcaacagga ttcacggttt tatggatttt
     2761 catactagct ccaatctcaa agaatgtact aatactcttc gaaaatctct tcaaaccgcg
     2821 tcaactttat ctgcaacctc aaagcagtgc tttgaacagc ctgcggctag ctttctagtt
     2881 tgctctttga ttttcattga gtataaatta agtatagcac agttagggag aataggtaag
     2941 gatttaaaat gaacttaaaa accagcatga ctagatgaag acaggctggt tatcaattta
     3001 tcaatattgg aaaggtgtca attgcccttc ataggttgca taaactccgt cattagcttg
     3061 tttgatagac gtgatgttta gagtgctacc gtagttggct tctcatttgt cgctatattc
     3121 actataagtt atcctactgg gcaggttctg gtcgttagca tagtattgaa cgagtttttt
     3181 atagctttgc tggctgaata ggaacaggca gcaaactcct aacattagga gagcaaagat
     3241 agaaatagca gttttttcat aggtattctc cttataaact aaaggataga agaaagtatc
     3301 ttgaggattt ttatactctt caaaaatctc ttcaaaccgc atcaacgtcg ccttgccgta
     3361 tatatgtgac tgactttgtc agtcttatct acaacctcaa agcagtgctt tgaacagcct
     3421 gcggctagtt tcctagtttg ctcttggatt ttcattgagt attaattcca aaatccagtc
     3481 aaggtaccag tgtatgtgat acgagttcca ccgtttatct ttcgtatctt caatggaatt
     3541 ggggaagtca gaaagtcttt gggttacaat atggtttccg ttcttctatc tctccttcta
     3601 tcacctaagt ttaaaatcta acttcgtagt atattatgga ccaataattc agaattatca
     3661 agcaattttg aattattttt ttcttattct gttccaatct agttttcata ttcttaaaaa
     3721 agtgataaaa tggtaggaag aattggagag tagagatgcc gaaagaagtg aatttaacag
     3781 gcgaagaagt tgtcgcttta accaaagaat atttaacgga agaggatgtt cattttgtcc
     3841 ataaggcctt ggtctatgct gttgaatgcc acagtggtca atatcgcaaa tcaggcgagc
     3901 cttatatcat tcaccctatc caagtggcag gtattttagc taagctaaag ctggatgctg
     3961 taacagtagc ttgtggattc ttgcatgatg tggtggaaga tacagatgcg accttggacg
     4021 atttggaaag agagtttggt cctgatgtgc gggtgattgt tgacggagtt accaagcttg
     4081 gcaaggtcga gtacaaatca atcgaggagc aattagcgga aaatcatcgc aagatgctca
     4141 tggccatgtc tgaggacatc cgcgttattt tggtcaaact gtctgaccgc ttgcacaata
     4201 tgcggaccct gaaacatctt cgaaaagaca agcaggagcg tatttccaaa gaaaccatgg
     4261 aaatctatgc cccacttgcc catcgtttgg ggatttccag tgtcaaatgg gaattagaag
     4321 acttgtcttt ccgttatctc aatccaacgg agttttacaa gattacccat atgatgaagg
     4381 aaaagcgcag ggagcgtgag gccttggtgg atgaggtagt cacaaaatta gaggagtata
     4441 cgacagaacg tcacttgaaa gggaagattt atggtcgtcc caagcatatt tactcaattt
     4501 tccgcaaaat gcaggacaag agaaaacggt ttgaggaaat ctatgatctg attgctattc
     4561 gttgtatttt agatacccaa agtgatgttt atgccatgct tggttacgtg catgaatttt
     4621 ggaaaccgat gccaggtcgc ttcaaagact atatcgccaa ccgcaaggcc aatggttatc
     4681 agtctatcca tacgactgtt tatggaccaa aagggccgat tgaattccag attcgaacca
     4741 aggaaatgca cgaggtggct gagtacgggg ttgcggctca ctgggcttat aagaaaggta
     4801 taaaggggca agttaacagc aaggaatcag ctattggaat gaactggatc aaggagatga
     4861 tggagctcca agaccaggct gatgatgcta aggaatttgt ggactctgtt aaggaaaact
     4921 atttggctga ggagatttac gtttttaccc cagatggagc tgtccgttcc cttcccaaag
     4981 attcaggacc gattgatttt gcctacgaaa tccataccaa ggtcggtgaa aaagcaactg
     5041 gtgccaaggt caatggccgc atggttccac tgacaaccaa gttaaagaca ggggatcagg
     5101 ttgaaattat cgccaacccg aactcctttg gacctagccg tgactggctc aatatggtca
     5161 agactagcaa ggcgcgcaat aagattcgcc agttctttaa aaaccaagat aaggaattgt
     5221 ctgtcaacaa gggtcgtgag atgctgatgg ctcagttcca agaaaatggc tatgtggcaa
     5281 ataaatttat ggacaagcgc cacatggatc aagttctgca aaagaccagt tacaagacag
     5341 aagactccct ctttgcggcc attggttttg gggaaatcgg tgcgattacc gtctttaacc
     5401 gtctgactga aaaggaacgc cgtgaggaag agcgtgccaa ggccaaggct gaggcagagg
     5461 agcttgtcaa aggtggcgag gtcaaggttg aaaataaaga aactctcaag gtcaagcatg
     5521 aggggggagt ggttattgaa ggtgcttctg gtctcctagt gcggattgct aagtgttgta
     5581 accccgtgcc tggtgacgat attgttggct acattaccaa gggtcgtggt gtggctattc
     5641 accgtgtgga ctgtatgaac ctgcgtgccc aagaaaacta cgagcaacgt ctccttgatg
     5701 tggaatggga agaccagtac tctagctcaa ataaggagta tatggcccat atcgatatct
     5761 acggtctcaa ccgtacagga ctgttgaacg atgtactgca agttctttca aatacaacca
     5821 agaatatttc aacggtcaat gcccaaccaa ccaaggatat gaagtttgct aatatccatg
     5881 tgtccttcgg tattgccaac ctctctacac tgactacggt tgtcgataaa attaagagtg
     5941 tgccagaagt ttactctgtc aaacggacca acggctagtt gtcctagctc ttactagaaa
     6001 ggctattatg aaaatcatta tccaacgggt taaaaaagcc caagtgagta tagaaggcca
     6061 gattcaggga aaaatcaatc agggactttt attgctagtt ggtgttggac cagaggacca
     6121 agaggaagat ttggactatg ctgtgagaaa actggtcaat atgcggattt tttcagacgc
     6181 agaaggcaag atgaacctgt ctgtcaaaga tattgaagga gaaatcctct ctatttctca
     6241 gtttaccctc tttgcggata ctaagaaagg caatcgtcca gcctttacag gggcagctaa
     6301 acctgatatg gcatcagact tctatgatgc tttcaatcaa aaattagcgc aagaagtgcc
     6361 cgttcagaca ggtatctttg gagcagatat gcaggttgag ctggttaata acggacctgt
     6421 taccattatc ctagatacta aaaagagata agaaagacca agcccagtcg gcttggtctt
     6481 tctcatcgat cataaaatac tccaaaaaga aatcggttct tgatatgctt gggggaagtc
     6541 tcttttcagg ctttggcaga tgcgatagga agggatgaga tgtcctagga tgaggagagt
     6601 tccctgaagg aaaagtggaa tatcacttaa agacaccaag gagagaatca tcaggctatc
     6661 ccataggaga atttgtaaag caaaacgcca gaatctcggc ctaatctggg aatagagttg
     6721 actaaagtgg tcacaaagtt ggtttgaaag ataggtcaat agcacaggat gaaagaaaat
     6781 gagccaacca ctataaatca aaatccagtc ccaagtaagc ccccctttta aatgtcaaaa
     6841 atgccagcat gattccatca atgacaagga gttgaatggt tttgatgaag atgatttttt
     6901 tcatgctaaa acctcctttt ccttagagac actcccataa agagatgtgt ttgtcgtaaa
     6961 agtctggata gttttctctt aggtagtcag ctgtcatata ataaaaagta gaatggcaag
     7021 cagtgataat tgacataaga gatgaaaaac gctgagaact aatgaaggct aagagaacaa
     7081 aaaatagaaa atcaatggtg agaaccccta aatagtagaa gcgaatcttt ttattgattt
     7141 gaggataaat ctcagcgaat tgatgtttga gtcggacgat caagagaaat agcaggagtc
     7201 cttgagcaag gaagaaaatt aaaccagaga gcaagagcca ctcaaaagat gtctcgagtc
     7261 tagtgataaa aaatgcaaat agtagcaaat caataactgc aattgctata aaatggattc
     7321 tatagagttt tttcatgaca agaccttcct cttttatcta acttcattct actccaaaag
     7381 aatgggagtt acaactaaaa tgataaaaat agcagaaggg agattctctt aagttggcta
     7441 gtattcttta tttgagtttc cttctatgta tctaacttct tcatcattcc agacaaataa
     7501 agctccgatt gcattgagga tataaaagat gtatttaccg atattggcga agtttccttg
     7561 aataccagct tttgtcagct gaacgaaatt gtaaatcaac caaaagcccc actgagttgt
     7621 tagtttcaat gcattcaaag cattggcaat gagggacagt gcaaaggcaa tagttgttac
     7681 gtaggcaagg agatccatct tgccctcata tccgatatag ttggtcacaa aggcaaagag
     7741 gaaggcgatg atggaaatga tgatggccgc caattttacc tgtttttggc tcatttggtt
     7801 gggtctgcct tcttgcgaag cttcccactt ctttatagca aaggtataaa tgaggaaggt
     7861 gacgggatag gtaatgatgg ccgccttatt tccaaggata taatcaatag caccgaacaa
     7921 aagggtatta acaataccaa agtaatttcc ccatttgctt aatttccccg tgaaacgagt
     7981 ggacaacatg gaaatcccaa cgttggttac ggaaatcaat ccaaagggta caagagctgt
     8041 ccatgatccc cagtctacaa atttatcgag gcgtgagttg agataaccag atgcaatcgc
     8101 aatcccaacg accaaagcaa ccccgaagag gtcaaatcat ttagatgtag caaaaatttt
     8161 tagtgatttt ttcataggtt aaactacctt tctttttttc aaatattctc ccattttttt
     8221 tcaaatattc taccaccaaa tgaaagtaaa ataaaatgat agaaataaaa ccctgaaaat
     8281 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
     8341 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
     8401 gctgaagcca tcaaactgct tgacttggag ctggtcaccg atgtgaagtg agtgcttgtc
     8461 cagataatgg agaatgtcaa aattatcgtg cacccgagtc aggcggtagg cgccagcttc
     8521 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
     8581 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
     8641 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
     8701 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
     8761 tagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgaggtt
     8821 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
     8881 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
     8941 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
     9001 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
     9061 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
     9121 gccttggagg ctgttttggc agatgctcgg cagataggag tggatgaata ctggcttttg
     9181 ggagatattc tcatgccagg gacaggacgt agaaggattt tggacttgtt ggatcaacta
     9241 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     9301 gaattggaca gtactcgccc cagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     9361 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     9421 cagtttgggg atttgacggt gggaattagc catcatctgc ctgataagaa ctgggggcga
     9481 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     9541 gatattgctg tttatggaca tattcaccag cagttgcttc gttacgggac tggtgggcaa
     9601 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     9661 gacttgcggg cccagtatat gattttggag tttgatgaca aaggcctggt agatatggac
     9721 ttccgacggg tagactacga tgtggcagcg gaattgcagc tggctaaaga cctgagactt
     9781 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     9841 gaatttttga gagaattggc tcagaaagag ggctgcgatc gggagttaga cgactggttg
     9901 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     9961 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
    10021 gcgactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
    10081 tttctggctg ctagtgtcgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
    10141 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
    10201 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
    10261 caactcttca gttttcatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
    10321 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcaa
    10381 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
    10441 atgccctctt ttttctttgg ataattatga taaaatgtag ctattaaagg agtaagaaat
    10501 gtatctcgtt ataggaattg tattagcctt tatagtgtca ttttggaagg ataatagaag
    10561 tttgtggaat ccagtattat ttttattatc cctcatttca agttattttt atctatccta
    10621 ccttttttat aaaaatggat acgagaatgt tcagttagct ttttatgtat ttgcctttgt
    10681 cttacttcct tttttgcttt ttctaagtgg catcttttta atctataatg gggtcatttt
    10741 gttgaagcga gagggacgtt ccaagcccca ttatctctca atgctctttg atttttattg
    10801 actattagat tctatttaaa aagatttaga atgcacatga aagtatgtat tctaggtctt
    10861 ttgttttgta tacatttaat tttcaagagt attatctatt tttccatgcc tggtaacgag
    10921 tatcaatcaa taactgggta aggcgaccca aggtttctct ttcttctgga gtgagggatt
    10981 gagcttggac aaagagatga tgaatgtatt caagcgcctt taaggaagcc aagtcattga
    11041 tagagctaat accagcctca agaatagtgc caaagaagag gtcgaagtag agctgaagtt
    11101 cttcgtcagg gactgtggcc acccattctt taaaggttgt gtctacttgc tggctatcac
    11161 tgttggtctt atccagttgg acgaagtgct tgtcctcaat ctgccaacta aaggtatcgt
    11221 gctgggcgat gccacccagg gcagtactct gaacgatgat ttggtgagca ggaatttcca
    11281 gcatcatacc gataatggaa ccttgtggaa tgaatatctt gcttctatcc attatccttt
    11341 gataacccgc agtctgtgtc aattcttgat ggagaccagg tgcatcaaat gtataaactg
    11401 ctgtgatctg attttgcaaa ctttgctcaa tttggctagc agcatagata gcgagatttc
    11461 ctcccttgga atgcccagcc agaataactt tttgcttagg atgatgggca aaaaagttct
    11521 ttaaatagcg aagggcgtgc ttttgagcag gaatttcctt catataggtc aggtggaaat
    11581 cttccttcca gccaatgata ctgtcatctg tcccacgaaa gacaatcaga taggtatcga
    11641 ggttgacacg ataagtcata gccgcaaatt gcttttgcag ttcagggtcg atgtcgttga
    11701 taaaatggga gagtttgcaa tttttgaagc gcttgtgttg agccaattta tctaataatt
    11761 gaaggcgatt tttgctagta agcatggtgg gctctcttgg aacctgaggt gctagatcta
    11821 aaagacgttg aggaagtgtg gagaccagat tatcaaagga gaggtaggtg atttctatta
    11881 aggttagaat gtctaactca ttcaagggaa ggtcgtaata agaatcatat gcgacatctt
    11941 tcagatagtc aaaaatattg gccataagag ctcctttctt tttatttatc ttagcaaatt
    12001 tccctcaaat tagctagtag cattgcctgt ttgtactggc taaaaacagg ctatttcaaa
    12061 ttcagtttca gaccatctgg catggaaaaa tctgttataa taatggaaaa ggagaagcgc
    12121 atgcacaaga ttttattagt ggaagatgat caggtcattc gtcaacaggt tgggaaaatg
    12181 ctctctgaat ggggatttga agtggtcctg gtagaagact ttatggaagt tttgagtcta
    12241 tttgttcagt cggaacctca tctggtcctc atggatattg gtttgccctt gtttaatggt
    12301 tatcactggt gtcaggaaat ccgcaagatt tccaaggtac ctatcatgtt tctttcttcg
    12361 agagaccagg ctatggatat tgtcatggca atcaatatgg gggcggatga ctttgtgacc
    12421 aagccttttg accagcaggt tcttttagct aaggttcagg gcttgttgcg tcgttcctat
    12481 gagtttgggc gtgatgagag tttgctggaa tatgctggtg ttatcctcaa taccaaatcc
    12541 atggatttac attatcaagg gcaagtcttg aatttgacca agaacgaatt ccagatttta
    12601 cgcgtgttat ttgagcatgc aggcaacatc gtagcacgtg acgacctgat gcgggaactt
    12661 tggaacagtg actttttcat tgatgataat accctctctg tcaatgtggc tcgtttgcgt
    12721 aaaaagttgg aggagcaggg attggtagga tttatcgaga ccaagaaagg aatagggtac
    12781 ggattgaagc atgcttgatt ggaaacaatt ttttctagcc tatctacgct cccgtagtcg
    12841 tctttttatc tatctgcttt ctttggcatt tcttgtctta ctctttcagt ttttatttgc
    12901 cagtctagga atttacttcc tctacttttt cttcttgtgt tgctttgtaa ccatcttatt
    12961 tttcacttgg gacatattgg tggaaacgca ggtctatcgc caggaacttc tctatggaga
    13021 gagggaagcc aagtctcctt tggaaatagc tttagcagaa aaattagaag cgcgtgagat
    13081 ggaactctat cagcagaggt caaaagcaga aagaaaactg acggatttgc tggattacta
    13141 taccttgtgg gtccatcaga taaagacccc cattgcagcc agtcaactct tagttgcaga
    13201 agtggtcgac cgccaactga agcagcagct agaacaggaa attttcaaaa tcgactccta
    13261 taccaaccta gttttacagt acctgcgttt agaaagtttc catgatgatt tgctcttaaa
    13321 gcaggttcaa attgaggact tggtcaagga aataattcgt aaatatgctc ttttctttat
    13381 tcaaaaaggc ttaaatgtca atctacatga ccttgataaa gaaatcgtga cggataaaaa
    13441 gtggctgcta gtggttattg agcaaatcat ctcaaacagt ctcaagtaca ccaaggaagg
    13501 tggtctggag atttatatgg atgaccaaga gctttgtatc aaagatacgg gaatcgggat
    13561 aaaaaacagt gatgtcctcc gagtatttga acgtggcttt tcaggataca atggccgttt
    13621 gacccagcag tcctctggac ttggccttta tctatctaag aaaatttctg aagaactggg
    13681 gcaccagatt cgtatcgagt ctgaggtcgg aaaaggaacg acagtgcgga ttcagtttgc
    13741 tcaagtgaac ttagtccttg agtaaaaata gatgagaaaa agcctccaga ttggaggctt
    13801 ttatgctaga ctcttatttc tcaacgcgtg atttgttggc gatatcagct aggatagctt
    13861 gaacaaaatt atcaactgag acagtttgtg tttctttttg gccgtagcga cgaacgttga
    13921 ctgtttcgtc ttccatttct ttgtctccaa caattaattg gtaaggaatc ttgctggttt
    13981 gtgaagcacg gatcttgaac tgcatttttt cattgcgctc atctacgtct gcacggacac
    14041 cgcggtcacg gagtttcttg gccacttccc aagcgtagtc cacgtgtttt tcgttagata
    14101 ctgggatgag ggttacttgg tgtggtgcca gccatgttgg gaaggccccc ttgtagttct
    14161 caatcaagat agctgtgaag cgttccatag ttgagataac cccacggtgg atcatgactg
    14221 gacggtgatc ttcgccatca gctccgatgt atttgaggtc gaagcgttct ggcaacaaga
    14281 aatcaagttg gatagtagaa agggtttctt cttttccaag ggcagtttta atctggatat
    14341 ccaattttgg tccgtagaag gctgcttcac cttcggcttc aaagtagtcc acgcccattt
    14401 catcaagagc tgcacgaagc atggtttggg cattttccca catctcatcg ttatcaaagt
    14461 acttatgagt atcttgaggg tcacgaagag agaggcggaa gcggtagtca gtcaagttga
    14521 agtcttcata aacatcgata atcaactgaa gggcacgttg gaattcttct tggatttgtt
    14581 ctggagtaac gaataggtga ccgtcgttga gtgacatttc acgtacacgt tgaaggccag
    14641 tgagggcacc agatttttcg taacggtgca tcataccgat ttcagcgata cggattggca
    14701 attcacggta agagtgaaca tggtgtttga aaacttggat gtggtgcgga cagttcattg
    14761 gacgaaggac aaattcttcc ccgtcaccca tgtccatggt tgggaacatg tcttcttggt
    14821 aatgatccca gtgaccagaa gtcttgtaaa gctcaacaga agcaagtggt ggagtgtaga
    14881 cgtgttggta gccagaagcc aactctttgt ttacgatgta gcgttccaat tcacgacgga
    14941 tagtcgcacc atttggtaac cagaatggca aaccttgtcc cacttcttgt gaaatcataa
    15001 agaggtcaag ctctttacca agtttacggt ggtcacgttc cttagcttct tcacgcattt
    15061 gaaggtagtt tttcaagtct ttcttgtcaa accaagctgt accatagata cgttgcatca
    15121 tagcgttgtc gctgtttcca cgccagtacg caccagctac atggagaagg tggaagattt
    15181 ggatacgacc tgttgatgga acatgaggtc cacggcagag gtctacatat tcaccctgac
    15241 gatagatagt caaaccgcct tcgtcttctg agtgttcttc aatcaattcc aacttgtaag
    15301 ggtcattttt gaagatttca cgtgcctcgt ctttagtcac ttcttcacga atagatggga
    15361 agttttcttt gacgattttt tgcatttctt cttcgatacg aggaaggtct tcgttagaga
    15421 tttgaccagc tgtgttgtca gtatcgtagt agaaaccatc ttcgatggct ggaccaactc
    15481 ccaagtgaat gtctgggaaa agacgacgag ctgcttgggc gaacaagtga gctgctgagt
    15541 gacgcaagat tggaagggca tcttcgtgat caggtgtcac aatttcgatg cttccatctt
    15601 cagtgatagc gcgagtagtg tcgatgagtt tgccgttgaa tttaccagcc aaggcttttt
    15661 tagctaggga attgctgata gattgggcaa tttcaaaagt tgttacgcca gattcgaatt
    15721 cacgaacagc gccatctggg aaagtaatgt taatcatgat gttctccttt tttattattt
    15781 catagtttct aagcattgat tttttatcag cagactactt ccgagtccta acgttcaatt
    15841 gcttttcttt atcagagagg aagttttcca tttccgtcag aatgtctata tccaaacgtt
    15901 gagaaagttc taatagccac cagatatttt ctgaaagttt ttgttccagt gtgtagggtg
    15961 tttcatcata gtagcgtcct tgctttgtca tcaccagtca ttggaaattt ccaatatcat
    16021 tagataaagc caagaggtct tcttctaccg tccacttgaa atcatgatgc ttaacttcca
    16081 gttcgtgata agcttgtcgg attgcccaac tgcgctccac taattcttgc aactccataa
    16141 ttagtatcct aataaaaaaa tgcgacatcc tcgaaaggac gtcgcaacgt ggttccacct
    16201 tcatttatgt acctcaaaag agagggacac ctctgatcgg ctctaacgtg gccaccgttt
    16261 tatgttttca taaaaaactc aagagtagta tcagtttaga cttcctatgc gtttccagca
    16321 accacgcact ctctagtaga aagggactaa gtgacttgtc tctatggatt attatagcat
    16381 gattgtgaga tttttcaagg attttgtgaa agttttttgt ttttcatttt ttgtagaata
    16441 tgcttgatgc taataccaga atccatgccg accagagcaa ctgtttcata gattagcaag
    16501 taaattagta taaactcacc aaaggttatg atagtaaagt aaaagagcag tccgttacca
    16561 actaaccatc aaagtgagaa acggaaacgg tagctataga gtaacgatat aatcaagatt
    16621 accagaggtg taaagaagag aagattgttt atatagagtt ccttgagtgt aagggggtca
    16681 gaaacaacta gtaagaacaa ctcataaagt ggtcaataaa agaataatat gaccagatag
    16741 taggggagat gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa
    16801 cttagatctc ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac
    16861 aaagaagatt tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat
    16921 aataattaag caagactatt gacattgatt attaagagtg tcacaattat tgtaactaaa
    16981 ataattacaa caagagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa
    17041 gcggggaaag caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt
    17101 cgttctgaaa acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca
    17161 aaagatgatc ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat
    17221 acgctaccgc tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag
    17281 acacgttttc tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca
    17341 cgacttttag atacgtctga ttttcctgaa gaatttaagt cactagcaaa agatcaagcg
    17401 gatgaattgg atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct
    17461 gtagatttta ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt
    17521 actactaatg aaaaaggaat aagccagatt agttatgcag attatgctat tggattggta
    17581 gatgaacttg aaaaaggtca tcatataaaa gaacatatct ctttacttga aaaataataa
    17641 ctatgagagt attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta
    17701 aagacaaata acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa
    17761 taaaaaggag aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat
    17821 atgcacgtca cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg
    17881 aaatcaacca ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg
    17941 gattgatgaa aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg
    18001 ttaaccgtta ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa
    18061 tgctgtcaaa agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga
    18121 gattttatct tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataatga
    18181 agctactcta aattgggtag cttttttgcg ttgtcacctt acctcgctat actcaagtat
    18241 aatctttggt tacggttcct agcactgtaa ggtaaaataa accagctttt ctcccttcgg
    18301 ggagattttt tttgtttcac tgaaagtttc gtacgatctt cgcctcgtcg cctagtctat
    18361 aaacgattta tctagcaaga atcatgatgc taagggcgtc aaaaatccgt atgaaaatag
    18421 ggaaatgaca cagtgttcga tgagcacaag gagtttcatc tttttcacta ggattttagc
    18481 ccgggctcaa atcagctctc tgacttcaga gggctttttt attgaggttt tatcggtaac
    18541 aattttggag actacaaaaa cctcaaacgg tatcagctaa ttacaccata aaggtgcgca
    18601 gttactcggc ttttcaagcc gagtagctgt atgcaagccc cctagaagag cccactcttt
    18661 acaaagtaaa gtatagtatg ttatacttta catggaagta gtcactgaat tccagttaga
    18721 aattactttg taactacgtt ttgaggagga gtaaaatgct ttcctacgtt cgacattacc
    18781 cactagcgat agctaaatta atgtgtctgt gctctcctaa aatctgctga tttattactg
    18841 actaatacag gagttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt
    18901 tccaccagta tcgattattt aattatttta attattttat ttgcacagct atcacagaat
    18961 aaacagaaat ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg
    19021 agtttagttg ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt
    19081 ggtttaatcc ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa
    19141 gaagaggaag aaattattga aagattagaa caaagcaagg caaatcaact gttttggaca
    19201 gttacattgc tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt
    19261 gcttcgttag attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt
    19321 atcttttgcg agattagtcg ggtgttatcc tctattccgt taatattcga gacaattgaa
    19381 aaatacgagc gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat
    19441 gaaaatggca cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt
    19501 agcccgagct caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga
    19561 caatcttaaa gttactctat tgtagagtgg cttttgattt gattaggaga ttcttataaa
    19621 tatagtaaaa tgaaataaga ataggacaaa tcgatcagga cagtcaaatc gatttctaaa
    19681 aatgttttag aagtagaggt gtactattct agttccaatc tactatataa atgaaaacct
    19741 tagctgtttg gccaaggttc atttcttcta tgcaagttct tctcttttct tatctgggtt
    19801 ccagatgaag cttgcgataa agctaaagat gatggttagg atagcgagga taatagcaag
    19861 gatgagggca gggatgcgga taaaccacca gagtggattt ggttttttat cattgtgcca
    19921 ttgtttcgtt tcttcgtcca gacgttggaa ttctgtttga atacgattgg cgactgtttc
    19981 aatgccttca tcattcattt tcttgatatc tgagatatcg attggatttc caaagttcat
    20041 atcgacacgt tcacggctaa tcaagccctt caaagtcatg ggaccggtgt aggtaaccgg
    20101 catgatacgg accttggcca ttttggcaat cagtgctgcg ccccccttga catcgtttga
    20161 gtggcggcta ccacttggaa acatgatgag agagcggtca ctttttttga gaacgttgat
    20221 aggatatttg atggctgagg cgctgggatt ttcacggtcg atgggaaagg cgccacacat
    20281 acgaatccac caaccaaaga tacggttggt aaagagttct ttttttgcca taaagatgaa
    20341 ctgttttggc ttggtcgcaa aggccatata aacaggatcc caccaggtac ggtgaggcgc
    20401 aactaaaata taattttcat cttgattagg aattttatca gtattatgat agtgagcatt
    20461 gccattgatg gaccataaga gcaatacaac taatccacgc aaataagtat aaaacatgcg
    20521 atctccttcg attgttttct tgttattatt ataccttatc aaaggagggc tggcaaactt
    20581 ttcccttgac tagatacata tttaggatga aattagaatt ctgttaaaaa aaatgatata
    20641 atagaattta tggataaaaa taagattatg ggattaaccc aaagagaagt caaggaaaga
    20701 caggctgagg gtttggtcaa tgactttacc gcatcagcca gtaccagcac ttggcaaatc
    20761 gttaaacgaa atgtctttac cctttttaac gctttgaact tagccattgc tttggctctt
    20821 gcctttgtgc aggcttggag caatctggtc ttctttgctg ttatctgctt taacgctttt
    20881 tctgggattg tgaccgagct acgagccaaa cacatggtgg acaagctcaa tctcatgacc
    20941 aaggaaaagg tcaaaaccat ccgtgatggt caggaagttg ctcttaatcc tgaagaatta
    21001 gtgctaggag atgtcattcg tttgtctgca ggagagcaga ttcctagtga tgccttggtt
    21061 ttggaaggct ttgcggaagt caatgaagcc atgttaacgg gagaaagtga tttggtgcaa
    21121 aaggaagttg acggcttact tttgtcagga agtttcctag ccagtgggtc agttttatct
    21181 caagttcacc atgtcggtgc agacaactat gctgccaaac tcatgcttga ggctaagacc
    21241 gttaaaccca tcaactcccg tatcatgaaa tcgctggaca agttggctgg ttttactggg
    21301 aagattatca ttccctttgg tctggctctc ttgctggaag ccttgctttt aaaaggcctg
    21361 cctctcaagt catccgttgt aaactcgtcg acagctcttt tgggaatgtt gcctaaggga
    21421 attgcccttt tgaccattac ttcgctcttg actgcagtga ttaagttggg cttgaaaaag
    21481 gtcttggtgc aggagatgta ctctgttgag accttggcgc gcgtggatat gctctgtctg
    21541 gacaagacgg gcaccatcac ccaaggaaag atgcaggtgg aggctgttct tccactgacg
    21601 gaaacttacg gtgaagaggc tattgccagc atcttgacta gctacatggc ccatagtgag
    21661 gataagaatc caactgccca agccattcgc cagcgttttg tgggagatgt tgcttatcct
    21721 atgatttcca atcttccctt ctccagcgac cgcaagtggg gggctatgga gttagaaggc
    21781 ttggggacag ttttcttagg ggcacctgag atgttgctgg attctgaagt cccagaagcc
    21841 agggaggcct tggagagagg atcacgtgtc ttggtcttag ctctcagtca ggagaaatta
    21901 gaccatcaca aaccacagaa accatctgat attcaggctc tagccttgct ggaaatcttg
    21961 gaccccattc gagagggagc agcagagacg ctggactatc tccgttctca ggaggtggga
    22021 ctcaagatta tctctggtga caatccagtt acggtgtcca gcattgccca gaaggctggt
    22081 tttgcggact atcacagcta tgtagattgc tcaaaaatca ccgatgagga attgatggcc
    22141 atggcggagg agacagctat tttcggacgt gtttcccctc atcaaaagaa actcatcatc
    22201 caaacgttga aaaaagcggg tcatacaacg gctatgacag gggacggggt taatgatatc
    22261 ttggcccttc gtgaggcgga ttgttctatc gtgatggcgg agggagatcc agcaacccgt
    22321 cagattgcca atctggttct cttgaactca gactttaatg atgttcctga gattctcttc
    22381 gagggtcgtc gcgtggtcaa taacattgcc cacatcgccc cgattttctt gataaagacc
    22441 atctattcct tcctgttagc agtcatctgt attgccagtg ctttactagg tcggtcagag
    22501 tggattttga ttttcccctt cattccgatc cagattacca tgattgacca gtttgtggaa
    22561 ggtttcccac cattcgtttt gacttttgag cgaaatatca aacctgtcga gccaaacttc
    22621 ctcagaagat ccatgcttcg tgccctacca agtgccctca tggtcgtgtt tagcgttctt
    22681 tttgtgaaaa tctttggaac gagtcaaggt tggtctgagt tagaaatctc aactctcctc
    22741 tattatctct tggggtcaat tggtttctta tccgtattta gagcctgcat gccattcact
    22801 ctatggcgag tcctcttgat tgtctggtca gtaggaggct tcctagccac agctctcttc
    22861 ccaagaatcc aaaaactgct tgaaatttca accttgacag aacaaacgtt gcctgtttat
    22921 ggtgtcatga tgttggtctt tacagtgatt ttcatcctga ctagtcgcta tcaagctaga
    22981 aaataaagaa agactgcaat ctgtggattg cagttttttt aggtacaaga ttgccagccg
    23041 aaatgtggta taataagagg taatagagtt ttggaaagtg agagaagatg atttcaaaga
    23101 gattagaatt ggtagcttcc tttgtgtcac agggggctat tttactagat gtgggaagtg
    23161 accatgctta tctgcctatc gagttggttg agagaggcca aatcaaaagc gctattgcag
    23221 gtgaggtggt ggaaggtccc tatcagtctg cggttaaaaa tgttgaggct cacggcctaa
    23281 aggagaaaat ccaagtccgt ttagccaatg gcttggcagc ttttgaagag actgatcaag
    23341 tgtctgtcat taccattgct ggcatgggtg gtcgtttgat tgctaggatt ttagaagaag
    23401 gtttggggaa gttagctaat gtagagcgtt tgatcctcca gcccaataat cgtgaagacg
    23461 acttgcgtat ctggctacag gatcatggat tccagattgt agcagaaaga atcttagaag
    23521 aagctggaaa gttttatgag attttggtgg tggaagcagg acaaatgaag ctatcagcca
    23581 gtgatgttcg ctttggtccc ttcttgtcca aagaagtcag tccagtattt gtccaaaaat
    23641 ggcaaaaaga agctgagaag ctagagttcg ccctcggaca aatcccagaa aaaaatctgg
    23701 aagaacgtca agttctagta gataagattc aagctatcaa ggaggtgctc catgttagca
    23761 agtgaagtga tccaagctta tgaagccttt tgccctcagg aattttctat ggagggagac
    23821 agctgtggtc tgcaaattgg cactttagac aagggtatcc aaagggtcat ggttgccctc
    23881 gatattcgtg aagagacggt ggctgaagcc attgaaaagg gtgtagactt gattatcgtc
    23941 aagcacgcgc ctatctttcg tcctatcaag gacttgcttg ccagccgtcc gcaaaatcag
    24001 atttacatcg acctgattaa gcatgacatc gcagtttatg tcagccatac caatattgat
    24061 atcgttgaaa atgggctcaa tgactggttt tgtcagatgc taggaatcga ggagacgact
    24121 tatctgcagg aaacaggtcc agaacgtgga attggacgta ttgggaatat tcagcctcag
    24181 acattttggg aattggccca acaggtcaag caagtctttg acctagatag ccttcgaatg
    24241 gtgcattatc aagaggatga tttgcagaag cctatttcaa gagtagcaat ttgtggtgga
    24301 agcggacagt ctttctataa ggatgctttg gcaaaggggg cagatgtcta tatcactggt
    24361 gatatctact accatactgc tcaggatatg ctgtctgatg gcttgttagc attggatcca
    24421 ggtcactata tcgaagtgct ttttgtggaa aaaatcgcaa cactccttac tcaatggaaa
    24481 gagaaaaaag gctgggaact agagatttta cctagtcaag catcgaccaa tcctttccgt
    24541 catatctagt tagaaagtga agacaatgaa aaaagttgcc attattggag caggaattgt
    24601 gggagcaaca gctgcctact acctctcgag agaaagtgac ctagaggtgg ccgtttttga
    24661 ccatgagcaa ggtcaagcca ccaaggccgc agcaggaatt atcagtcctt ggttttccaa
    24721 acgccgtaat aaagcctggt acaagatggc gcgcttgggg gctgattttt atgtggattt
    24781 attagctgat ttagagaaat caggacaaga aatcgacttt taccagcgtt cgggagtctt
    24841 tctcttgaaa aaggatgaat ccaatttgga agaactttat caactggccc tccagcgcag
    24901 agaagaatct cccttgatag ggcaattagc cattctgaac caagcctcag ctaatgaatt
    24961 attccctggt ttgcagggat ttgaccgcct gctctatgct tctggtggag cgagagtaga
    25021 tggccaactt ttagtgactc gtttgctgga agtcagtcat gtcaagctgg tcaaagaaaa
    25081 agtgactctg acaccgttag catcaggcta ccagattggt gaagaggagt ttgagcaggt
    25141 tattttggcg acgggagctt ggttggggga catgttagag cctttaggtt atgaagtgga
    25201 tgtccgtcct caaaaaggac aactacgaga ttatcagctt gcccaagaca tggaagatta
    25261 ccctgttgtc atgccagaag gggagtggga tttgattccc tttgcaggtg ggaaattatc
    25321 cttgggcgct acccatgaaa atgacatggg atttgatttg acggtagatg aacccttgct
    25381 ccaacaaatg gaggaggcgg ccttgcctca ttacccagtt ttagctagag tgacttcaag
    25441 ggctgagcgt gtgggaatcc gtgcctatac cagtgatttc tctcccttct ttgggcaggt
    25501 gccagaattg gcaggtgtct atgcagccag tggactaggt tcatcaggcc tcacaactgg
    25561 tcctatcatt ggttaccatc tagcccaact gatccaagac aaggagttga ccttggaccc
    25621 tgaaaactac ccaattgaaa actatgtcaa acgagtaaaa agcgaataat actcaatgaa
    25681 aatcaaagaa caaactaggt aactagccgc gggttactca aagcactgct ttgaggttgt
    25741 ggatagaact gacgaagtca gctcaaaaca ctgttttgag gttgtagata gaactgacga
    25801 agtcagtaac catacccatg gcaaggcgac gttgacgtgg tttgaattgg attttcgaag
    25861 agtataagca ttttactgaa attttatcag gtagtttagg atggcaaatg acattccctg
    25921 tcaaaaatgg taaaataaga aaaaataatc tgagaatcga ggaaaaaaga tgcaagaaaa
    25981 gattttggta actggtggtg ccggttttat tggaacccac actgttattg aattgatcca
    26041 agcaggccat caagttgttg tggtggataa tcttgtcaat agcaatcgta agagtttaga
    26101 agttgttgaa agaatcacag gagttgagat tcctttctat gaggcagata ttcgtgacac
    26161 agataccctc agagatattt tcaagcagga agaaccgact ggtgtcattc actttgctgg
    26221 tttgaaggct gttggcgaat caacacgtat ccctcttgcc tactatgaca acaatatcgc
    26281 tggaactgtc agccttttga aagccatgga agaaaacaac tgtaaaaaca tcatcttcag
    26341 ttcttctgcg acagtttacg gggatccgca cacagtgccc atcttggaag atttcccact
    26401 ttcagtgacc aacccatacg gtcgtactaa gctcatgcta gaggaaattt tgactgatat
    26461 ttacaaagca gactcagaat ggaatgttgt cttgcttcgt tactttaacc caatcggagc
    26521 ccatgagagt ggtgatttgg gagaaaatcc aaacggtatt ccaaacaatc tcttgccata
    26581 tgtgactcaa gtagccgttg gaaaattaga gcaagtgcaa gtgtttggag acgattacga
    26641 tacggaagat ggaacaggtg ttcgtgacta tatccacgtt gtcgatttgg ctaagggtca
    26701 cgttgcagct ttgaaaaaaa tccaaaaagg ttcaggacta aacgtttata accttggaac
    26761 tggtaaaggt tactcagttc ttgaaattat ccaaaacatg gaaaaagcgg tgggccgtcc
    26821 tattccttac cgcatcgtag aacgtcgccc aggtgatatc gctgcctgct actcagaccc
    26881 ggcaaaagct aaagcagaac tcggttggga agcagaactc gacatcaccc aaatgtgtga
    26941 agacgcatgg cgttggcaaa gcaagcatcc aaatggattt gaagactaag atgatgattt
    27001 caatcatcgt cccttgttta aacgaagagg aagtacttcc tcttttttat caggctctgg
    27061 aagctttact tccagatttg gaaacagaaa tcgagtatgt ctttgtcgat gatggatcaa
    27121 gtgatgggac cttggaactc ttaaaggcct atcgggagca aaatccggca gtccattata
    27181 tttctttctc tcgaaatttt ggcaaagaag cagcccttta tgcaggcttg caatatgcga
    27241 caggagattt ggtggtggtg atggatgcag acctccaaga tcctcctagt atgttgtttg
    27301 agatgaaaaa tgtactagac aaaaatgtag acttggactg cgttgggaca cggagaacta
    27361 gtcgggaggg agaacccttc tttcgcagtt tctgtgctgt tctcttttat cgcctcatgc
    27421 aaaaaatcag cccagtagct ctgccgtcgg gtgtccgtga ttttcgtatg atgagaaggt
    27481 ctgtggtcga tgccatttta agcttgactg agtccaatcg tttttctaag ggactctttg
    27541 cctgggtcgg ctttaaaacc cactatctgg actatccaaa tgtcgaaagg caggctggca
    27601 agaccagttg gagttttagg caactctttt tttactccat tgaagggatt gttaattttt
    27661 cagatttccc tttgactata gcctttgtag ctggtctcct atcttgtttt ctttctctgc
    27721 tgatgacctt ttttgttgtg gttcggaccc tcattttggg caatccgaca tctggttgga
    27781 cctctctgat ggctgttatt ctctttcttg gaggcattca actcttgacc attgggattc
    27841 tcggtaagta tatcagtaag atttatttag agactaaaaa aagaccactt tatcttatca
    27901 aagaaaaaag tgaccttcct gattttacag aaaaaaataa agtgaaaaga ctataatttt
    27961 acatggaaat gtgctaaact agagggagtg gattatcgcc attgatttag gcttcctggt
    28021 ttccaatcag ggcgcgagtt gggcaatttt taacagcctc taagacatcc tgactaggag
    28081 aaatttcttt ttccagttgg tcagggtcat cgtaaaaacg cacgattcca ttatcgtggt
    28141 aatcaaataa atcagaataa gtttggcaaa gcccacaggc gatacatcgt tcaggtataa
    28201 gtgtgatttt catgttcata tttatattgt aataagaaaa gtaaaaaaaa acaaggagta
    28261 aggtatggca aaagaaccgt ggcaagaaga tatctatgat caagaagaat caagagcaga
    28321 gcgtcggcat cgaaaccacg gaggggcgga taggatggct aatcgtattt tgacgatcct
    28381 agctagtatt ttctttgtaa ttgtggtggt gatggtcatc gttctcatct atctatcatc
    28441 gggggggagt aatcgcacag cagccttaaa agactttcat gattctgatg caagtgtagt
    28501 acaaatctca tcttcaagca gttctcagcc tgagcagagt tcagagccag aatctacttc
    28561 tagtagttca gaagaagctg ctaatcctga aggaacgatt aaagttctcg caggagaagg
    28621 ggaagcagct attgccgctc gtgcaggaat ctccattgct cagttagagg ccttgaatcc
    28681 tgggcacatg gctacaggat cttggtttgc taatccaggt gatgttataa aaataaaata
    28741 ggagccgata tgaaaacaat tcaaattgct attgatggtc ctgcttccag cggtaagagt
    28801 acggtcgcaa agattattgc taaggatttt ggattcacct accttgatac aggagctatg
    28861 tatcgtgcag cgacctatat ggctcttaag aaccaattag gagttgaaga agtcgaagcc
    28921 cttctagcct tgttggacca gcatccaatc agctttggac gttcagaaac tggagaccag
    28981 cttgtttttg taggagatgt ggatattacc catcctatcc gtgaaaatga agtgaccaat
    29041 catgtttctg ctattgcagc aattcctgaa gtgcgtgaga aactggtttc tctccaacaa
    29101 gaaattgccc agcaaggcgg gattgttatg gatggtcgcg atattggaac tgttgtattg
    29161 ccgcaagcag aattgaaaat tttcctagta gcttctgttg atgagagagc agagcgtcgt
    29221 tacaaggaaa atattgccaa gggaattgaa acagaccttg aaaccctaaa aaaggaaatt
    29281 gctgcgcgtg actacaagga tagtcatcgt gagacttctc ctctcaaaca agcagaggat
    29341 gctgtctacc ttgatacaac tggtttgaac attcaagaag tagttgaaaa aatcaaagca
    29401 gaagctgaaa aaagaatgta aatgtagaaa agccgataga ttgatatcgg tttttttcta
    29461 aatttgtcaa aatgctgatt ttagggtata atagttgctg ttcgagaaat tttgattttc
    29521 aaagaatagt gaatgatgat aaggagaaac catgaacaat ttaccaaatt gtccaaaatg
    29581 taactcagag tatgtctacg aagacggtgc cctactggtt tgcccagagt gtgctcatga
    29641 gtggaatcct gctgaagttg cagaagtaga agaaggtctt gtcgctatcg atgccaacgg
    29701 aaataaattg actgatggtg atacagtaac tctcatcaag gacttgaaag taaaaggtgc
    29761 gccaaaagat ttgaaacaag ggacgcgcgt gaaaaatatc cgcatcgtag aaggcgacca
    29821 caatatcgac tgtaagattg atggttttgg tgccatgaaa cttaaatcag agtttgtgag
    29881 gaagatttaa gcatgtcaaa acactataaa cttgtatttt atagccgtat cttcttgttt
    29941 ctagcggctt ttacgggagt ttatcttgaa attactaggc atggtggttt tgggatgctt
    30001 ctctattaca cggttctgtc caaccttttg gtaactattt ttacccttta tcttctaaag
    30061 gttatgagcc gtgtaggtga aaattggcaa aggccaagtc tcttgcgctt aaaaggtggg
    30121 gtcaccatga gtatcatgat tacctgtgtg atttaccatt tcctcttggc gcccattgcg
    30181 actaatttct ataccctaga aaatttcctt tgccactata tcgttcccat ctggttttta
    30241 gcggataccc tcttttttga caaacagggt caatacaaga tttgggatcc agcagtgtgg
    30301 accattttac cctttctgta tatgatgttt gctcttttta atggcttggt tctaaaactc
    30361 aatattccaa atgccaagga taatcctttc ccttacttct ttttgaatgt gaacaagggt
    30421 tggaatgttg tgtttaagtg gtgtctgatt atctttgttg cctatatggt agcaggattt
    30481 attttctact ttatcaagca aatcaagaga aagtcatcct aatactcttc gaaaatctct
    30541 tcaaaccacg tcagtttcca tctgcaacct caaaacactg ttttgagcag cctgcggcta
    30601 gcttcctagt ttgctctttg attttcattg agtataagat acaagggatt cattttcgaa
    30661 tttaagaagg agtctacaaa ccaatgaggc ttcttctttt cttgcttatt tgataactat
    30721 caaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    30781 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    30841 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    30901 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    30961 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31021 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31081 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31141 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31201 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31261 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31321 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31381 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    31441 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    31501 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    31561 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    31621 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    31681 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    31741 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccattcgtt
    31801 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    31861 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    31921 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    31981 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttc ctaatagagt
    32041 tgttcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32101 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcaagagt ataagatttt
    32161 tatacccata caatatttgt tttaggtcct tgtttacaga ctaatttctt gataaaatag
    32221 aggttatgac gagatataaa gcaactattt cctatgatgg ttatgccttt gctggctttc
    32281 agcgccagcc tcatgcgcgt agcgttcagg aagaaattga aaaaaccttg accagattaa
    32341 ataaagggca aaccattact gttcacggtg ctggtaggac agatagtggg gttcatgccc
    32401 tgggacaggt cattcatttt gacctgcctt atcagatgga tgaggagaaa ctccgttttg
    32461 ccttggatac ccagtctcct gaagatattg atgtgatttc gattgagctt gtggcagctg
    32521 attttcattg ccgttatgcc aagcatagca agacctatga gtttattgtg gatagaggac
    32581 gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt tccctaccca ctcgatgtgg
    32641 aacgaatgca gattgcaatc aaaaagctag agggaaccca tgattttacc ggttttacag
    32701 cctctgggac tagtgtagag gataaggttc gcaccatcac agaagctagt ttaatagtcg
    32761 atgagacagg acaatttttg acctttacct tttcaggaaa tggtttcttg tataaacaga
    32821 ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa ccgcatgcca gtagagcaga
    32881 ttgatctcat cttggagaag aaggacaggc aacttgcagg tcccactgca gcaccaaatg
    32941 gtttgtattt aaaggagatt cgttatgaag aataatcgta ttttagcact ttctggaaat
    33001 gatattttta gtggtggtgg actgtcagct gatttggcta cctatacctt gaacggcttg
    33061 catgggtttg tagcagtgac ttgtttgaca gccttgacag aaaaaggatt tgaagtcttt
    33121 ccaactgatg ataccatttt tcaacatgaa ttagatagct tgcgtgatgt ggaatttggg
    33181 ggaattaaga ttggtcttct ccctactgtc agtgtggctg agaaggcctt ggactttatc
    33241 aaacaacgcc caggagtacc tgtggtgttg gatcctgtct tggtctgcaa ggaaacgcat
    33301 gatgtagctg tcagtgagct ctgccaagag ttgattcgct ttttccctta tgtcagtgtg
    33361 attacgccta atctcccaga agcagaatta ttatccggtc aggaaattaa aaccttggaa
    33421 gacatgaaaa ctgcagcgca gaaattgcat gatttaggag cgccagcagt cattatcaag
    33481 ggaggcaatc gtcttagtca ggacaaggct gtggatgtct tttatgatgg acagaccttt
    33541 actatcctag aaaatccagt tatccaaggc caaaatgctg gtgcaggttg tacctttgcc
    33601 tctagcattg ccagtcactt gattaaaggt gataaacttt tgccagcagt agaaagctct
    33661 aaggctttcg tttatcgtgc tattgcacaa gcagatcagt atggagtaag acaatatgaa
    33721 gcaaacaaaa acaactaaaa tcgcccttgt atccctatta accgcccttt ctgtggttct
    33781 aggttatttc ttaaaaatcc caacacctac aggaattcta actcttttag atgctggtgt
    33841 cttctttgcg gccttttact ttggtagtcg tgaaggagcg gtagtcggag gactagcaag
    33901 tttcttgatt gacctcttat caggctaccc tcagtggatg ttctttagct tggtcaacca
    33961 tggcttgcag ggatttttcg caggatttaa aggaaaaagt cagtggttag gccttatttt
    34021 agcaactatt gccatggtag gaggctacgc cttgggttct actttgatga atggctgggc
    34081 agcagccctc ccagaaattc taccaaattt catgcaaaat atggtaggga tgattgtagg
    34141 atttattctt agtcaaagta tcaagaagat taagtaatac tcttcgaaaa tctcttcaaa
    34201 ccacgtcagc ttccatctgc aacctcaaaa cactgttttg agcagcctga ggctagcttt
    34261 ctagtttgca ctttgatttt cattgagtat aaagaggttg agtaaaaagt atttcaaata
    34321 agaaaaacgc atagtatcag gtgttgaatg aactgccccc caaaagttag acagaaaaaa
    34381 tctaactttt ggggtgtttt attatgaaac taacttatga tgataaagtt cagatctatg
    34441 aacttagaaa acaaggatat agcttagaga agctttcaaa taaatttggg ataaataatt
    34501 ctaatcttag gtacatgatt aaattgatta atcgttacgg aatagagttc gtcaaaaaag
    34561 gaaaaaatcg ttactattct cctgatttaa aacaagaaat gattaatcaa gtctgacatg
    34621 aaggctggac taaagataga gtttctcttg aatacggtct cccaagtcgt acgatacttc
    34681 ttaactggct agcacaatac aggaaaaacg ggtatactat tgttgagaaa acaagaggga
    34741 gagtacctaa aatgggacgt aagccaaaaa cgagacctga agagaggaca gaattagaat
    34801 atcttcaagc agaaaatgag tacctgagag cggagaatgc catcctaaaa aagttaagag
    34861 aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc aagaattaat
    34921 gactgagttt tcgttagttc ttcttctaaa atccattaaa ctagctcgtt ggacctacta
    34981 ctatcacttg aaacagctag acaaaataga taaggaccaa gagcttaaag ctgaaattca
    35041 atccattttt atcgaacaca agggaaatta tacttatcgc cgggttcatt tagaactaag
    35101 aaatcgtggt tatctggtaa atcataaaag agttcaaggc ttgatgaaag tactcaattt
    35161 acaagctaaa atgcgacaga aacgaaaata aaggagacgt tggtaagaag acagagaatc
    35221 tcattcaagg ccaatttgaa ggctctaaaa caatggaaaa gtgctacaca gatgtgacag
    35281 aatttgccat tccagcaagt actcaaaagc tttacttatc accagtttta gatggcttta
    35341 atagcgaaat tatcgcctat aatctttcaa cttcacccaa cttagaacaa gtacaaacaa
    35401 tgttggaaca ggcattcaca gagaagcact acgagaatac gattctccat agtgaccaag
    35461 gctggcaata ccaacacgat tcttatcatc ggttcctaga gagtaaggga attcaagcat
    35521 ccatgtcacg caagggaaac agcccagaca atggtatgat ggagtccttc tttgggattc
    35581 tgaaatcgga aatgttttac ggttatgaga agtcgtttca gtcgcttaag caattggaac
    35641 aagccattat agactatatt gattattaca acaacaagag aattaaggta aaactaaaag
    35701 gacttagccc tgtgcaatac agaactaaat ccttcggata aattaattgt ctaacttttt
    35761 ggggggcagt tcattctaca cccactatta tgcgttttat tgtgggaaga ttttcctcat
    35821 tttctagtga aattgaactt tttctaacat cttttgatag atgacttctt aatcaattat
    35881 catttccatt gttgtttctt ggggtttcat cccttgtctt tgataaaagc ggagagcacc
    35941 ctcgttatca ttccagacac ttagggttag attattgcag ccaatttctt tagcataata
    36001 gcagaaaaat gacaataaaa tagcccctag atattttgaa aggaaagcat aggggctata
    36061 tagtttaatc aaaataaagc aaatctttgc tggtgcttgt aaagaggtcg aagccatcct
    36121 tggtaacaac accgcagtct tcaatacgaa caccgacttt accagggata tagatacctg
    36181 gttcaacaga gaagcacatg ccttcttcga tgaccatgtc gtttccttcc atgatagatg
    36241 ggaattcatg gacatccata ccgataccat gcccgagacg gtggttgaag tactcaccat
    36301 aaccagcttt ttcgatgacc tcacgggcag cgcggtccac ttcatgagca gtcacacctg
    36361 gcttgataaa gtcaagagca gcttgttggg cttcaagagt caagttgtaa atatctttct
    36421 tgaattggtc tggtttgccg acagcgactg tacgagtcat atctgacgca tagccattga
    36481 ccagaacacc caggtcaaag aggagaagag catcattttc aaccttatta gctgctggaa
    36541 tgccgtgtgg attcgcagca ttatcaccag tcaagaccat ggtatcaaag ctcatttcat
    36601 aaccttcacg tttcatggca aagtcgattt gtgcgatgat atctgtctca gtcttatcaa
    36661 gagaaatatt gtcaaaacca acatgaacag ccttgtcagc ataaagacct gcaaccatca
    36721 ttttttgcac ttcatcagct gatttgatga ggcgcatgcg ttggatacga ggagtgaggt
    36781 tgtcaaactc agcagtctca aaaactgttt tcaaaccatg gtatttggtc aagatgagat
    36841 tgtcaaactc aacagcgaca cgtttgaagt caagttgtgg aagagcatgt ttgatttttt
    36901 gccatggatt ttcagaatcg acatagccca ctactgggaa ggaaacggtg ctacttgcac
    36961 gttctacttc aagagctggg acaaagagga gaggttcctg atccgctagg acaaagagga
    37021 acatttggcg ttcatgggga tcactgtaaa aaccagtgag gtaattgatt gtgacggggt
    37081 cagatacgac agcgacgtct agtttttctg attcaagata tgttaggatt tgttgtaatt
    37141 tagacatatg ctaccttctt tctacccctc tattttggca aaaaatgaga gaaaatgcaa
    37201 gggagaaggg taaaagaaaa gacaaaaaac tccgacaaga taacggagtt ctttgatatc
    37261 attttccttt gtttaagaaa agtcagcctt gcttttgacg tcactgtact cttcagcgat
    37321 ttcttggctg aggatatcct cataggcagg gagttggata tcctgaccat atttcttctt
    37381 gagggcagta gtaactaggc gataagccag attggcatta cgagagagga taggcccgtg
    37441 gaagtaggaa ccaaagacat tcttataatg aaccccttca ccgacctttt cttcgttgtt
    37501 tccatttcca tagacaacct gtcccagcgg tttttggtca tcagagagga aggtacggcc
    37561 ttggtgattt tcaaatccat agtaggtttc atcgaaatct tcattgtgaa tcttgatgtc
    37621 accgataaaa cggttattgg tctggttgag cgtgtagtgt cccatgaccc ctagcccttc
    37681 gatacgtttt cctgaagctt caacataata ttgacccaat agttggaaac caccgcagat
    37741 agccagaact acaccgtcgt tttggatgta gttgtcaatg ctctcttttt tagcaggtag
    37801 gtcgtctgca atgatacttt gttcaaagtc ttgaccacca ccgaaaaagg cgatgtcgta
    37861 gtgattttca tcaaagtcat catggagaga aacgatgtca acggtcacat gggctcccag
    37921 tttttcagcc acatacttga gcatgaggat gtttccattg tccccgtagg tattcatgag
    37981 atttccgtag aggtgggcaa tgttgagctg ataggggtaa ttgccatctt ttgaggaaag
    38041 tgaagtataa accattagtt catctccttt ctaacaatct gacgactagc cagcagttca
    38101 cgaaattcca gcatggcagt ataagttgcc agaatatagg catgcttgca gtcttgattc
    38161 tcaatggtct tgagaacttg ctccagatta ctcgtttcag tgattttctc agctggatag
    38221 ccagtcactc ggaggcgacg agcgatttca gaatgacgaa caccaccagc gttgatttca
    38281 ggaatgtcca tgtcagtgat ttgttcaaag tctgcatccc agatccagct agtgtcaatt
    38341 ccatctgcat agttggcatt aaggaggaca gataggctaa atggataagg tgctagtttg
    38401 atcatttcga tagcttgggt tgcaccgact ggatttttaa tcaagacaag ggtacattcc
    38461 ttgtcaccga tatgaaaggt ttcttggcgt ccaaagacag cacggctctt gtcaaatccc
    38521 tgtttgatga gttgcgaatc ggcacctagg aaacgggcga tggccacagc agctagggcg
    38581 ttatagatat tatagagccc gccgatttgg ataccgtatt cttggccgtc tatgacaaag
    38641 cgagagcgat tgttggtcaa ctcaaccagt tttgtcaaac gatagtcgag atcaggacgt
    38701 ttgcatccac aaccttcaca gatataggca cccaagtttg cataggtatt atgctcatat
    38761 ttgaggatgc cttggcagtc aggacagaga atcccttcgg tattgtagtg agccagttgg
    38821 gctggtcctt tttccaagtc aaaaccaaaa tactctatag ggtttggaat agttggcttg
    38881 tagaaaagtg gactgtctcc gttaaggaga acagtagcag ttggaacttt ccgaatggct
    38941 tccaatatca tgttataggt agtatagatt tcaccgaaac ggtccatctg gtcacggaag
    39001 atattagtaa tgacaaaaag actaggctgg atatagtcac agatacgaga tagactggct
    39061 tcgtcaattt cgaggacggc aatatttttc ccagtttttg aagatttggc tgttaggaag
    39121 gttgttgcaa tccctgtaat catgttggca ccgcttgggt tggttagaac ttgaccataa
    39181 acctctttta aaatgccgac agtgagggca gttgtcaggg tttttccatt tgttccagtg
    39241 acaacgacaa tctcgtagtt cttagctagg ttttgtaaaa tatctttatc aaattgaagg
    39301 gcgactttac ctgggagcgt acttccacgg ccaagacggc ttaaaatgaa gtgggaagaa
    39361 cgcccagcaa gaaggcccaa agtagttttt aagttcatgt ttctattata tcataaaaga
    39421 ggagaaagac agatttgaga ttccgcagaa gtaaaaacag cccaaagagg gctgttcgat
    39481 acgattaaat ctcaacttaa atcgcaaaca agtcattcaa gttctcagcc aaggttgggt
    39541 gagtgaagat ttgttttgtg aagtaagtgt aaggaatctt gttgtccata gcaacagtga
    39601 tgatgttgat gatttcttga gaaccttctg agaagatgct tgctccaaga atttcttttg
    39661 tttcagtatt gacaacagct ttgaaggcac cgcgaaggtc tccatttacg tgaccacgag
    39721 gcattgctgc aacggggatt tccttaacag cgtatggaag tttcaaatca gctgcttggc
    39781 tttcagtcaa accaacttgt gaaagtgcag gtgtgatgaa catagtattt ggcacattga
    39841 gacggtcttc aagtgtgtag ctgccatctc cagcaaggta gctgtaaaca acacggaagt
    39901 catcaagtga aatgtaagta aattgaaggc caccgttgac atctccaact gcaaagacac
    39961 caggaacgtt tgtttgacag tgtttgtcta ctttaatagc accacgttca gttagttcaa
    40021 tatctgtatt ttcaagttga agtggttcta catttggttt gcgtccagtt gcgtagagaa
    40081 gggcgtcgaa acggtaagtt tcgtcttcag ttacgacaag cacttggtca ccatcgtttt
    40141 tgatttcagt agtatggata ttttgaagca attcaatgcc atcttcttcc atgtattgtt
    40201 tagcaagagc tgcgatggaa ggttctgcac gaggtaggaa tgtatccaag gcatctagga
    40261 ctgtgacctt gcttccaagt ttgttgtaaa ggccggcaaa ttcaagaccg atatttccgc
    40321 caccaaggat tccaagtttt tcaggtaatt tgtccaagct ttggatacct gttgagtcaa
    40381 agatgttttt gcttgtagca agtccaggga ttggcaagac gtttgaaaca gcaccagtgt
    40441 tgatgacgat tgtttcagca gtcagttctt tcttttcatc accagcttgg atttcgatga
    40501 ctttatttga aaggaagtga gcttccgcat caaagatatc tacgcctgta ccagcaacag
    40561 tcgcatagtt tttaccgttg aggcgaccag tgatcgtgtt tttagtagca atgacttctt
    40621 caaaagacaa gtccttttca gcagcaacta gcaaggtttt agttgggata caaccaatgt
    40681 tgatacaagt tccaccgtac atagccttgc tgcgttcaac gagggcaact tttttgccag
    40741 ctgaagccaa tttacctgct agtgttttac cagctttacc aaatccaata acaattaaat
    40801 cgtatgttaa catttatctt cctcctattc gaatttcatt ctagcacaag aaaaaaactt
    40861 ttgcacaatt ctgctacgga aaagacagaa aaagataaaa acgctttcca gacaaaaaac
    40921 tagtaatttt ttgacaagct tgataaacta aaatcctatc tatttttata taagatagaa
    40981 taaatgttcg aaaataggag gttttatgaa atcgaatcgt tatattattg cctttgctgg
    41041 ggtcatttta cacttaatgc tgggttcgac ttatgcttgg agtgtttatc gtaaccctat
    41101 tattgaaaaa acgggatggg atcaggcttc tgttgccttc gcctttagtc tagcaatctt
    41161 ttgtttgggt ttatcggctg catttatggg gcgtttggta gaaaaatttg gtccgaaagt
    41221 catggggagt ctatctgctt ttctatacgc aggtggaaat atcttaacag gatttgcaat
    41281 agaccgtcag gaactgtggt tgttgtatct agcttatggc attttaggtg ggcttggttt
    41341 gggagcaggc tatattaccc ctgtgtcaac gattataaaa tggtttcctg ataaacgtgg
    41401 tctcgcaaca ggtttagcga ttatggggtt tggttttgct tctttattga ctagtcccat
    41461 agcgcaacac cttatcgcag gggtagggat tgtagaaact ttttatattt taggagcaag
    41521 ttactttatt atcatgctcc tagcttcaca attcattaag cgtccaaatg agcaagagct
    41581 tgcaatttta tcttcttcag ggaaagaaaa aacagcctct ttgacgcaag gaatggctgc
    41641 aaatcaggct ctaaaaagca atcggtttta tatgctttgg attattttct ttatcaacat
    41701 agcttgtggt ttaggcttaa tttcagcggc atcgccaatg gcacaggaga tggctggctt
    41761 gtctacaagt catgcagcag taatggtggg tgttttgggg attttcaatg gatttggtcg
    41821 cttgctctgg gcgagtttgt ctgactatat cggtcgccct ctaaccttta gtatattact
    41881 gcttgtcaat cttttctttt ctctctcact ttggctcttt acagattccg ttttatttgt
    41941 agttgctatg tctattttga tgacttgcta tggagctggt ttttctttga ttccagctta
    42001 tctcagtgat atttttggaa ccaaggaatt ggccgctctg catggttata ttttaacagc
    42061 ttgggcaatg gctggtttag cgggacctat tttattagca gagacttata aaatggctca
    42121 ttcgtacaca caaaccttgt tcgtttttct cattttatac agtatcgcct tggctttgtc
    42181 ttattatcta ggtcgttcaa tcaaaaaaga aagtcaaaaa ccgcttacat gattttctgt
    42241 agaaatgggg ctatcttttg ctctggtctt gtgttatact agataggttg caaagaaaac
    42301 agtacttttc ttttgtggaa aagaagcaac acgattttat atctagttat atgaaaatac
    42361 gtcataaaaa gaaaagtata aactaagccc tatagggtgg cttcgcacca cctttagaaa
    42421 gaagaataac gtgaaattta atgaattaaa cttgtctgct gatttgctag cagaaattga
    42481 aaaagctggt tttgtagaag ctagtcctat ccaagaacaa actattcctt tggcccttga
    42541 aggcaaggat gttatcggtc aagctcagac tggtacagga aaaactgcag cctttggctt
    42601 gcctaccctt gaaaaaatcc gtacagaaga agcgactatc caagctttgg tcatcgctcc
    42661 aactcgtgaa ctagctgtcc aaagtcaaga agaactcttc cgctttggtc gtagtaaggg
    42721 agtcaaagtc cgttcagtat atggcggatc aagcattgaa aaacaaatta aggctcttaa
    42781 atctggtgcc catatcgtgg tgggaactcc aggtcgcctc ttggacttga ttaaacgcaa
    42841 ggccttgaaa ttacaagaca ttgaaaccct tatccttgac gaagcggatg aaatgcttaa
    42901 catgggcttc cttgaagaca tcgaagccat tatttcccgt gtacctgaga accgtcaaac
    42961 tttgcttttc tcagcaacta tgccagatgc catcaaacgt atcggtgttc agtttatgaa
    43021 agcccctgaa catgtcaaga ttgcggctaa ggaattgaca acagaattgg ttgaccagta
    43081 ctatatccgt gttaaggaac aagaaaaatt tgacaccatg actcgtctca tggatgtggc
    43141 acaaccagaa ctcgctattg tatttggtcg taccaaacgc cgtgtggatg aattgactcg
    43201 tggtttgaaa attcgtggct tccgtgcaga aggaattcat ggcgacctag accaaaacaa
    43261 acgtcttcgt gtccttcgtg actttaaaaa tggcaatctt gatgttttgg ttgcgacaga
    43321 cgttgcagcg cgtggtttgg atatttcagg tgtgacccat gtctacaact acgatattcc
    43381 acaagatcct gagagttatg ttcaccgtat cggtcgtaca ggtcgtgctg gtaagtcagg
    43441 tcaatctatt acttttgttg ctccaaacga aatgggttac cttcaaatca ttgaaaactt
    43501 gactaagaaa cgcatgaaag gtctcaaacc tgcaagtgta gaagaatcct tccaatcaaa
    43561 aaaacaggta gctctcaaga aaatcgaacg tgattttgca gatgaaacca ttcgtgccaa
    43621 ctttgagaaa tttggtaagg atgctcgcaa attggctgct gagtttactc cagaagaatt
    43681 ggcaatgtat atcttgagtc tgacagtcca agacccagat agccttccag aagtggagat
    43741 tgcacgtgaa aaaccactac cgtttaaacc atcaggtaat ggtttcggtg gtaaagctaa
    43801 gggaggtcgt ggaggccgtc gtggggacga ccgtcgagag cgtgatcgcc gtggcaatgg
    43861 tcgccgtgat gagttcaaaa aaggaagtcg tggcaacgat cgttttgata aggaaaaacg
    43921 ttaccgtaag gataataaaa aaccacgcaa tactttaaac gaaaagcaaa caggctttgt
    43981 tattcgtaac aaaggtgata aataagaaaa agcggttcaa aatgaatcgc ttttttatat
    44041 aaggagaccg aatgtgaaaa agacaaataa aattattata ttatctttta taatattatg
    44101 atacacaaaa ataggcaact tgtcaataga aaaggaacaa tttaattaaa aatattctgg
    44161 tttttaatta aattgtaagt caatgcaagt caataaggaa ttttcagata attattgaaa
    44221 aagagacgtt tttatgttat aatgatagcg attaaattcg aggtgaaaaa tggcacattt
    44281 attagaaaaa actagaaaaa ttacatcaat tttgaaacgc tcagaggagc agttgcagga
    44341 tgagcttcct tacaacgcta ttacgcgtca gttagcggat attattcatt gcaatgcctg
    44401 cattatcaat agtaagggac gtctgcttgg ctattttatg cgttataaaa caaatacaga
    44461 tcgcgtagag caattcttcc aaactaagat tttcccagat gactacgttc aaggggctaa
    44521 tatgatttac gaaacagaag caaacttacc tgttgagcat gatatgagta ttttccctgt
    44581 tgagagtaga gatgattttc cagatggctt gacgactatt gcaccgattc atgtatcggg
    44641 gattcgcctt ggttctttga ttatttggcg taatgataaa aaattcgaag atgaggactt
    44701 ggttcttgtt gagattgcca gtaccgttgt tgggattcag cttcttaact tccaacgtga
    44761 agaagatgag aaaaatattc gtcgtcgtac tgctgtcacc atggcggtca ataccctttc
    44821 ttactccgaa ctccgtgctg tttcagcaat tttaggggaa ttaaatggaa atgaagggaa
    44881 gttgactgcg tcagtgattg cagatcgtat cggaatcact cgctctgtga ttgtcaatgc
    44941 tcttcgtaaa cttgagtctg cggggattat tgaaagtcgc tcacttggaa tgaagggaac
    45001 ctatcttaag gtcttgattt cagatatttt tgaagaagtg aagaaaagag attactaatg
    45061 acaaaggctt taatttcgat tgattataca gaagattttg ttgctgatag tgggaaacta
    45121 acagcaggtg ctccagctca ggcgatttcg gatgccatca gcaaggtaac tcgattagct
    45181 tttgaacgag gagattatat cttctttact attgatgctc atgaagaaaa cgattgtttc
    45241 catccggaaa gtaagttatt tcctcctcat aatctgattg ggacgagtgg acggaattta
    45301 tatggagatt tggggatctt ttatcaagag catggttcag acagtcgtgt cttttggatg
    45361 gataaacgcc attactcagc tttttcaggg actgacctag atattcgttt gagagagcgt
    45421 agagtgtcta ccgttatctt aacaggtgtc ttgacggata tctgtgtcct acatacagct
    45481 atagatgcct ataatctagg atatgacatc gagattgtta aaccagctgt tgcttccatc
    45541 tggcctgaaa atcatcaatt tgccctaggt catttcaaaa atacactcgg agctaagtta
    45601 gtagatgaaa atctaaatga actttctgag taacctggtt ggtgaaaatg aaaaaatttg
    45661 aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc gacgcgggga
    45721 tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg tcgtgagggt
    45781 tcaagtccct ctctccgcat aggaaaagag ctagctcttt tgtatttctc taaaaaatta
    45841 gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg gaaaactgat ccttgtttct
    45901 gcttttgtca tagaagaata ataaagatta tcttcttcaa attctccgat attctctaaa
    45961 gttttgtgca agttgcacag aactttttta tttttttggt catcttgcca tagaaatata
    46021 aagcgttttc atctataata taattatcaa aagataaaag gagttcacct catggtagaa
    46081 ttgaatctta aaaatattta caaaaaatat ccaaacagcg aacactattc agttgaagat
    46141 ttcaacttga acatcaaaga taaagaattt atcgttttcg taggaccttc aggatgtggt
    46201 aaatcaacta cactccgtat gattgctggt cttgaagaca ttacagaagg tactgcatct
    46261 atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc gtgatatcgc catggtattc
    46321 caaaactacg ctctttaccc acacatgact gtttatgaca acatggcttt cggtttgaaa
    46381 ttgcgtaaat acagcaaaga agacattaac aaacgtgttc aagaagcagc tgaaatactt
    46441 ggattgaaag aattcttgga acgtaaacca gctgaccttt caggtggtca acgtcaacgt
    46501 gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat tcttgatgga cgaacctttg
    46561 tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg aaatcgctaa aattcaccgt
    46621 cgtatcggag ctacaactat ctatgtaact cacgaccaaa cagaagcgat gacacttgca
    46681 gaccgtatcg ttattatgtc agctactaag aaccctgctg gtacaggtac tatcggacgt
    46741 gtagaacaaa tcggtactcc tcaagaagtt tacaaaaatc cagttaacaa atttgttgca
    46801 ggattcatcg gaagcccagc tatgaatttc atcaacgtga aattggttgg tagcgaaatt
    46861 gtttctgacg gtttccgttt gaaagtgcca gaaggagcat tgaaagttct tcgtgaaaaa
    46921 ggctacgaag gaaaagaatt gatctttggt atccgtccag aagacgtgaa tgcagaacct
    46981 gctttccttg aaacattccc agactgtgtt gtaaaagcga ctatctctgt atcagaactg
    47041 cttggttcag aatctcacct ttactgccaa gttggtaaag acgagtttgt tgcaaaagtt
    47101 gatgctcgtg actacttgca aacaggtgca acagttgagc ttggatttga cttgaacaaa
    47161 gcacacttct tcgatgtaga aactgaaaaa acaatctact aaaataaata aaattcaaag
    47221 cactacaaga aaagatatct ctttatcaat tgtagtggag agatatcagt taatctaggg
    47281 agagaaacaa aatgcttctc tcctttttgc tagggaagtc atattatgca tctatattgt
    47341 gatgctcttt aatactcttc gaaaatctct tcaaaccacg tcaacgtcgc cttgccgtac
    47401 gtatgattac tgatttcgtc agttttatct gcaacctcaa agatgtactt tgagcagctt
    47461 acggctagtt tcctagtttg ctctttgatt tccattgagt attatttgtg ggtaccatct
    47521 acaagtgaag ctatatgcgt aaactacgtg agcaattgaa ttcgaactag agaggtaata
    47581 ataaatttat gctatagtta tggtgacttg tatgcttttg attctagttt atcaaataat
    47641 agattagaat tgtcagataa tatcattttg tgttataatg aagaaaaaac agaggtgttc
    47701 aaatgtcaga agcaggtcat aagtttttag caaaattggg gaaaaaacgc ttacgtccag
    47761 gtggaaagcg tgccacagat tggttaattg cagaaggagg attttcaaaa gaaaagagaa
    47821 tactagaggt tgcgtgtaat aggggaacta cagcaattga gttggcacag cgttttggtt
    47881 gcaagataac tgctgttgat atggatgctc aagctttaga agtggctaaa aaatctgctg
    47941 gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc aaatgcaatg aaacttcctt
    48001 atcaagatgc tagttttgat attgttataa atgaagctat gctgactatg caagccgatc
    48061 aagctaagaa aaaatgtgta atggaatatc taagggtatt aaaacctgga ggtcttctct
    48121 tgacacatga tgtacttctt aaggaagcta aagagtctat cagacaggaa ttatcacaag
    48181 caattcatgt aaatgtaggt cctttaactc aagatggttg ggaacaggtg atgatagaat
    48241 caggttattg tgatgtgaaa gcattgactg gtgaaatgac attaatgaaa ttatcgggta
    48301 tgatttatga cgaaggtttg ctaggaactt tgaaaatttg tgtaaatgct tgtaaaaagg
    48361 agaatagaaa gcagttttta actatgtata aaatgtttgc taagaataaa cagaaattgg
    48421 gctttattgc gatggctagt tataaatcgt caaaacgtta gataattatt gaagttaact
    48481 tttccttttt tctttcttaa aaaatatgct ataatagaga gtaaaaaact ttgaaagaaa
    48541 gaaaaaagat gaatttaaaa gattacattg caacaattga aaattatcca aaggaaggca
    48601 ttaccttccg tgatattagt cctttgatgg ctgatggaaa tgcttatagc tacgctgttc
    48661 gtgaaatcgt tcagtatgct actgacaaga aagtcgacat gatcgtggga cctgaagctc
    48721 gtggatttat cgtgggttgt ccagttgcct ttgagttggg aattggtttt gcgcctgttc
    48781 gtaagccagg taaattgcca cgcgaagtta tttctgctga ctatgaaaaa gagtacggtg
    48841 tcgatacctt gactatgcac gcggatgcca ttaagccagg tcaacgtgtt cttattgtag
    48901 atgacctttt ggcgacaggt ggaactgtta agacaactat cgagatgatt gaaaaacttg
    48961 gtggtgttat ggcaggttgt gccttccttg ttgaattgga tgaattgaac ggccgtgaaa
    49021 aaattggtga ctacgattac aaagttctta tgcattatta atgaaaacag tccctagggc
    49081 tgttttctct acactaggat ataaaaatag actataacta gttagagaaa aactataatt
    49141 gaaaactata tcttcttaca gtataataaa aggactaagt gtttgagatt tgtcttcaaa
    49201 catatgcaat tattcctgaa agagtacagt taggagaggg ttatgccgat tcgaattgat
    49261 aaaaaattgc cagctgttga gattttacgg acagagaata tctttgtcat ggatgatcaa
    49321 cgtgctgccc accaagatat ccgtcctttg aagattttaa ttttaaatct catgccacag
    49381 aaaatggtca cagagaccca gttgttgcgc cacttggcta atacacccct acaactggat
    49441 attgattttc tctatatgga gagccaccgt tctaaaacaa ctcgttcaga gcacatggag
    49501 accttctata aaacttttcc tgaagtcaag gatgagtatt ttgatgggat gatcatcacg
    49561 ggtgctccag ttgagcattt accatttgag gaagtggact attgggagga atttagacag
    49621 atgcttgagt ggtctaagac tcatgtctat tcgacccttc atatctgttg gggggctcag
    49681 gctgggcttt atctgcgcta tggtgtagaa aaataccaga tggacagtaa gctatcaggt
    49741 atttatcctc aggacaccct aaaagagggt caccttctat ttagaggctt tgatgatagc
    49801 tatgtatccc ctcattcacg gcacacggag atttctaagg aagaggtctt aaacaagacc
    49861 aatctcgaga ttttatcaga aggacctcag gttggggttt ctattttggc cagtcgtgat
    49921 ttacgagaaa tttatagttt tggtcatttg gagtatgacc gtgatacctt ggcaaaagag
    49981 tattttcgag atcgtgatgc aggtttcgac ccacatattc cagaaaatta ctttaaagat
    50041 gatgatgtta atcaggtacc ttgtctttgt tggtcttcat ctgcagccct ctttttcagt
    50101 aattgggtaa accatgcggt ctatcaggag acgccttttg actggagaaa gatagaagat
    50161 gatgcatctg catataggta tttataagag gaattatgac atatttagac gcttttaaat
    50221 caggtacctt ggttttaccg agtgccctgc tcttgcattt taaggaactc tttccttcta
    50281 gcgacgattt tctggtttgg caatttttct atttgcaaaa tacgacaggc ttagaagaaa
    50341 tatcgccaag ccagattgct gaaaggattg gcaaggaaat ttcggatgtc aaccagtcca
    50401 tttctaatct gacggaaagg ggactgctcc agtatcgtac tatcgaatta aatggcgaaa
    50461 ttgaattgct ctttgatgct agtttggcct tggaacgttt ggatgacctg tttggagcag
    50521 ttcattcaag ttcagaccag ctaacaccac aaaaccagct caaggatttg gtggaaacct
    50581 tccagcagga gttgggacga ttgttgacgc cttttgagat tgaggatttg accaagacac
    50641 taaaggaaga tggaaccagt gctgacttga ttaaggaggc tcttcgtgaa gctgttttga
    50701 acggaaaacc aaactggaag tacattcagg cgattttgag aaactggcgc catgaaggaa
    50761 tcaagagtgt ggctcaaatt gaggccaaga gagcagaaag agaagcaagc aatcctcagt
    50821 tgacacaggt atctgcagat ttcataaatg ccatggatct ctggaaggat taatccatgc
    50881 aagtaggctt gaaatccgag taagatttgc aagctgtgta taattgtgat agaataaata
    50941 gaaaataaat tgaaaaaaga ggtatgtgaa atgtcacgta aaccatttat cgctggtaac
    51001 tggaaaatga acaaaaatcc agaagaagct aaagcattcg ttgaagcagt tgcatcaaaa
    51061 cttccttcat cagatcttgt tgaagcaggt atcgctgctc cagctcttga tttgacaact
    51121 gttcttgctg ttgcaaaagg ctcaaacctt aaagttgctg ctcaaaactg ctactttgaa
    51181 aatgcaggtg ctttcactgg tgaaactagc ccacaagttt tgaaagaaat cggtactgat
    51241 tacgttgtta tcggtcactc agaacgccgt gactacttcc atgaaactga cgaagatatc
    51301 aacaaaaaag caaaagcaat ctttgcgaac ggtatgcttc caatcatctg ttgtggtgaa
    51361 tcacttgaaa cttacgaagc tggtaaagct gctgaattcg taggtgctca agtatctgct
    51421 gcattggctg gattgactgc tgaacaagtt gctgcctcag ttatcgctta tgagccaatc
    51481 tgggctatcg gtactggtaa atcagcttca caagacgatg cacaaaaaat gtgtaaagtt
    51541 gttcgtgacg ttgtagctgc tgactttggt caagaagtcg cagacaaagt tcgtgttcaa
    51601 tacggtggtt ctgttaaacc tgaaaatgtt gcttcataca tggcttgccc agacgttgac
    51661 ggtgcccttg taggtggtgc gtcacttgaa gctgaaagct tcttggcttt gcttgacttt
    51721 gtaaaataat cagtaagtag caaaagctag gtggaacagc attcagatgt ctgttacatt
    51781 ttttatagga gagaaagatt gaaaacaaaa attggattag caagtatctg tttactaggc
    51841 ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag caaaaacttc gcaggataca
    51901 acgacagctt caagtagttc agagcaaaat cagtcttcta ataaaacgca aacgagcgca
    51961 gaagtacaga ctaatgctgc tgcccactgg gatggggatt attatgtaaa ggatgatggt
    52021 tctaaagctc aaagtgaatg gatttttgac aactactata aggcttggtt ttatattaat
    52081 tcagatggtc gttactcgca gaatgaatgg catggaaatt actacctgaa atcaggtgga
    52141 tatatggccc aaaacgagtg gatctatgac agtaattaca agagttggtt ttatctcaag
    52201 tcagatgggg cttatgctca tcaagaatgg caattgattg gaaataagtg gtactacttc
    52261 aagaagtggg gttacatggc taaaagccaa tggcaaggaa gttatttctt gaatggtcaa
    52321 ggagctatga tgcaaaatga atggctctat gatccagcct attctgctta tttttatcta
    52381 aaatccgatg gaacttatgc taaccaagag tggcaaaaag tgggcggcaa atggtactat
    52441 ttcaagaagt ggggctatat ggctcggaat gagtggcaag gcaactacta tttgactgga
    52501 agtggtgcta tggcgactga cgaagtgatt atggatggtg ctcgctatat ctttgcggcc
    52561 tctggtgagc tcaaagaaaa gaaagatttg aatgtcggct gggttcacag agatggtaaa
    52621 cgctatttct ttaataatag agaagaacaa gtgggaaccg aacatgctaa gaaaatcatt
    52681 gatattagtg agcacaatgg tcgtatcaat gattggaaaa aggttattga tgagaacgag
    52741 gtggatggtg tcattgttcg tctaggttat agcggtaaag aagacaagga attggcgcat
    52801 aacattaagg agttaaaccg tctgggaatt ccttatggtg tctatctcta tacctatgct
    52861 gaaaatgaga ccgatgctga gaatgacgct aaacagacca ttgaacttat aaagaaatac
    52921 aatatgaacc tgtcttaccc tatctattat gatgttgaga actgggaata tgtaaataag
    52981 agcaagagag ctccaagtga tacagacact tgggttaaaa tcatcaacaa gtacatggac
    53041 acgatgaagc aggcgggtta tcaaaatgtg tatgtctata gctatcgtag tttattacag
    53101 acgcgtttaa aacacccaga tattttaaaa catgtaaact gggtagcggc ctatacgaat
    53161 gctttagaat gggaaaaccc ttattattca ggagaaaaag gttggcaata tacctcttct
    53221 gaatacatga aaggaatcca agggcgcgta gatgtcagcg tttggtatta agcgatgatt
    53281 tgaaagaggg atgtgatagt agcaccctct ttttctttgt tttatgatag ttcatcctcg
    53341 agtaaattca agatcttgct cggaaatgaa gcttatatag tagattgaat atagacaaat
    53401 accttgtgat tggtaaaaca ttttagaaat tcatttacct ttcctaatcg acttggtttc
    53461 atcttatttc aatctattat agtattgggg aatttcttca aaccacatca gcttggtcag
    53521 ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg ggtttagttt cctagtttgc
    53581 tgatggattt ccattgacta taagcatcca accctctttt tgtcttctaa agaattctta
    53641 aattatcagt ctattgcaac ttttctcata taagttcttt gtcttgctat ttgttttcct
    53701 tagtagtata ctaaggtagt aatcattaag aagtggttac aaaaaataat gaatgaggta
    53761 aagaaaatgg tagaattgaa aaaagaagca gtaaaagacg taacatcatt gacaaaagca
    53821 gcgccagtag cattggcaaa aacaaaggaa gtcttgaacc aagctgttgc tgatttgtat
    53881 gtagctcacg ttgctttgca ccaagtgcac tggtatatgc atggtcgtgg tttccttgta
    53941 tggcatccaa aaatggatga gtacatggaa gctcttgacg gtcaattgga tgaaatcagc
    54001 gaacgcttga ttacactcgg tggaagccca ttctctacat tgacagagtt ccttcaaaat
    54061 agtgaaatcg aagaagaagc tggtgaatac cgtaatgttg aagaaagctt ggaacgtgtt
    54121 cttgttatct accgttactt gtcagaactt ttccaaaaag gtttggatgt cactgatgaa
    54181 gaaggtgacg atgtgacaaa cggtatcttt gcaggcgcta aaactgaaac agataaaaca
    54241 atttggatgc ttgcagccga acttggacaa gcacctggtt tgtaagaaat aaggaaacat
    54301 agataaatct gtaggaaatt tcttacagat tttttctatt ttgtaagcta ttccaaacca
    54361 gtcttttttt gagttttttg ataaaatagt actatcagtg aaaaggatgg aagcatgact
    54421 aagaaaatcg tagctatttg ggcccaggat gaagagggtg tgattggtaa ggaaaatcgt
    54481 ctgccttggc atttgccagc agaattgcag cactttaaag aaacaactct gaatcatgct
    54541 atcttgatgg ggcgtgtgac ctttgatggg atggggcgtc gcttgcttcc aaaacgggaa
    54601 accctgattt tgacgcgtaa tccggaagaa aagatagatg gggttgctac ttttcaggac
    54661 gtccagtctg ttcttgactg gtatcaggat caagaaaaga atctctacat tatcggtggg
    54721 aagcaaattt ttcaggcttt tgaaccttac cttgatgaag tgattgtcac tcacattcat
    54781 gctcgggtgg aaggagatac ctatttccct gaagagcttg acttgtctct ttttgagaca
    54841 gtttcaagca aattttacgc caaagatgag aagaatcctt atgattttac catccaatac
    54901 cgcaagagaa aggaagtcta atggaacgga gtttatttgg tctattcacg gcttttctgt
    54961 gtttcatctg ctttctggca ggagcacagg cttttcgtaa aaagcgttac gggctttcta
    55021 tcctcctttg gttaaatgcc tttaccaatc tggtcaatag tattcatgct ttttacatga
    55081 ccttatttta gatagaatga cagtatagaa tggaaggaaa tcatgtctac aaatagaaaa
    55141 aatgatatga tggtttattg ctcattttgt ggcaaaaacc aagaagaagt acaaaaaata
    55201 attgctggca acaatgcttt tatttgtaat gaatgcgtgg agttagctca ggaaatcatt
    55261 cgagaagaat tggttgagga agtcttggca gacttgtctg aggtgccaaa accaattgaa
    55321 ctcctccata tcttgaacca ctatgtaatt ggtcaagatc gtgccaagcg tgccttggca
    55381 gtggcggttt ataaccacta caaacgcatc aatttccacg atacacgcga agagtcagaa
    55441 gatgtggatt tgcagaagtc aaacattttg atgattggcc caactggttc agggaaaact
    55501 ttccttgccc agaccttggc taagagcttg aatgtgcctt ttgctattgc ggatgcgaca
    55561 gctctgacgg aggctggtta tgtgggtgag gacgtggaaa atatcctcct caaactcttg
    55621 caggttgctg actttaacat cgaacgtgca gagcgtggca ttatctatgt ggatgaaatt
    55681 gacaagattg ccaagaagag tgagaatgtg tctatcacac gtgatgtttc tggtgaaggg
    55741 gtgcaacaag cccttctcaa gattattgag ggaactgttg ctagcgtgcc gcctcaaggt
    55801 ggacgcaaac atccacaaca agagatgatt caagtggata caaaaaatat cctcttcatc
    55861 gtgggtggtg cttttgatgg tattgaagaa attgtcaaac aacgtctggg tgaaaaagtc
    55921 atcggatttg gtcaaaacaa taaggcgatt gacgaaaaca gctcatacat gcaagaaatc
    55981 atcgctgaag acattcaaaa atttggtatt atccctgagt tgattggacg cttgcctgtt
    56041 tttgcggctc ttgagcaatt gaccgttgat gacttggttc gcatcttgaa agagccaaga
    56101 aatgccttgg tgaaacaata ccaaaccttg ctttcttatg atgatgttga gttggaattt
    56161 gacgacgaag cccttcaaga gattgctaat aaagcaatcg aacggaagac aggggcgcgt
    56221 ggacttcgct ccatcatcga agaaaccatg ctagatgtca tgtttgaggt gccgagtcag
    56281 gaaaatgtga aattggttcg catcactaaa gaaactgtcg atggaacgga taaaccgatc
    56341 ctagaaacag cctagaggtg actatggaac ttaatacaca caatgctgaa atcttgctca
    56401 gtgcagctaa taagtcccac tatccgcagg atgaactgcc agagattgcc ctagcagggc
    56461 gttcaaatgt tggtaaatcc agctttatca acactatgtt gaaccgtaag aatctcgccc
    56521 gtacatcagg aaaacctggt aaaacccagc tcctgaactt ttttaacatt gatgacaaga
    56581 tgcgctttgt ggatgtgcct ggttatggct atgctcgtgt ttctaaaaag gaacgtgaaa
    56641 agtgggggtg catgattgag gagtacttaa cgactcggga aaatctccgt gcggttgtca
    56701 gtctagttga ccttcgtcat gacccgtcag cagatgatgt gcagatgtac gaatttctca
    56761 agtattatga gattccagtc atcattgtgg cgaccaaggc ggacaagatt cctcgtggta
    56821 aatggaacaa gcatgaatca gcaatcaaaa agaaattaaa ctttgaccca agtgacgatt
    56881 tcatcctctt ttcatctgtc agcaaggcag ggatggatga ggcttgggat gcaatcttag
    56941 aaaaattgtg aggaaaagaa aatggcaaaa acaattcata cagataaggc cccaaaggct
    57001 atcggaccct atgttcaagg aaaaatcgtt ggcaaccttt tgtttgctag cggtcaagtt
    57061 cccctatccc ctgaaactgg ggaaattgta ggagagaata tccaagaaca gacagagcaa
    57121 gtcttgaaaa acatcggtgc tattttggca gaagcaggaa cagactttga ccatgttgtc
    57181 aaaacaactt gcttcttgag cgatatgaac gactttgttc cttttaatga ggtttaccaa
    57241 acggccttca aagaggaatt cccagctcgt tcagctgtgg aggtagctcg tcttcctcgt
    57301 gatgtaaaag tcgaaattga agtcatcgca gagattggat aagctagttg aagtttggtg
    57361 ttgccaaact tcttttgata taaggagaaa aagatgacaa agaaacaact tcacttggtg
    57421 attgtgacag ggatgagtgg cgcagggaaa actgtagcca ttcagtcctt cgaggatcta
    57481 ggttatttca ccattgataa tatgccgcca gctctcttgc ctaagttttt gcagctggtt
    57541 gaaattaagg aagacaatcc taagttggcc ttggtagtgg atatgcgtag ccgttctttc
    57601 ttttcagaga ttcaagctgt tttggatgag ttggaaaatc aagatggttt ggatttcaaa
    57661 atcctctttt tggatgcggc tgataaggaa ttggtcgctc gttacaagga aaccagacgg
    57721 agtcacccac tagcagcaga cggtcgtatt ttagatggaa tcaagttgga acgtgaactc
    57781 ttggcacctt tgaaaaatat gagccaaaat gtggtggata cgactgaact cactccacgt
    57841 gagctgcgca aaacccttgc agagcagttt tcagaccaag aacaagccca gtctttccgt
    57901 atcgaagtca tgtctttcgg atttaagtat ggaatcccga ttgatgcgga cttggtcttt
    57961 gatgtccgtt tcttgccaaa tccctattat ctaccagaac tgagaaacca aacgggtgtg
    58021 gatgaacctg tttatgatta tgtcatgaac catcctgagt cagaagactt ttatcaacat
    58081 ttattggcct tgattgagcc gattctgcca agttaccaaa aggaaggtaa gtccgttttg
    58141 accattgcca tgggatgtac gggtggacaa caccgtagtg tggcatttgc taaacgcttg
    58201 gcgcaggact tatccaagaa ttggtctgtt aatgaagggc atcgcgacaa agaccgcaga
    58261 aaggaaacgg taaaccgttc atgagaaaac caaagataac ggtgattggt ggagggactg
    58321 gaattcccgt cattctaaaa agtctgcggg aaaaagatgt ggaaatcgca gctatcgtga
    58381 cggtggcaga tgatggtggt tcttcaggtg aactccgaaa aaatatgcaa cagttgacac
    58441 cgccaggtga tcttcgtaat gtccttgtgg ccatgtcgga tatgcctaag ttttatgaga
    58501 aggtctttca gtatcggttc tctgaggatg ccggagcctt tgctggccat ccattgggaa
    58561 atctcatcat tgctggcttg tcagaaatgc agggttcaac ctataatgcc atgcagttat
    58621 tgagcaaatt tttccataca acagggaaaa ttcatccttc cagtgaccat cctttgaccc
    58681 ttcatgcagt ctttcaggat gggacagaag tggctggaga gagtcatatt gtagaccatc
    58741 gaggcataat tgacaatgtc tatgtgacca atgccctaaa cgatgatacg cctctggcca
    58801 gccgtcgagt agtgcagacc atccttgaaa gtgacatgat tgtcctaggg ccaggttccc
    58861 tctttacctc tattttgccc aatatcgtga ttaaggaaat tgggcgggct cttttggaaa
    58921 ccaaggcaga aattgcctat gtctgcaata tcatgaccca acgtggggag acggaacact
    58981 ttacagatag cgaccacgtg gaagtcttgc atcgtcacct tggtcgccct tttatcgaca
    59041 ctgtcttggt gaatattgaa aaagtgcctc aggaatacat gaattccaac cgttttgatg
    59101 aatacttagt gcaagtggaa cacgattttg taggtctttg taagcaagtt tcgcgcgtga
    59161 tttcatctaa cttccttcgt ctggaaaatg gcggtgcctt ccacgatgga gatttgattg
    59221 tggacgagtt gatgcgcatt atacaggtga aaaaatgagt ttcacagtag cagtaaaaga
    59281 agaaatcctg ggccaacacc atctgagctg gcatgaatta tctgccatta tcaaaatgtc
    59341 tggtagcatc ggtctctcga cttcgggctt gactttgtca gttgtgacag aaaatgccaa
    59401 actggcccgt cacctctatg agtcctttct ccatttctat gaaatcaaat ctgaaattcg
    59461 tcaccaccaa cggagcaatc ttcgcaagaa tcgcgtctat accgttttta cagatgaaaa
    59521 ggtgcaggat ttgttaagtg atttgcactt ggcagactct ttctttggcc tggaaacagg
    59581 tattgatgag gcgattttat cggatgagga agcaggtcgt gcctatctct gtggcgcttt
    59641 cttggcaaat gggagcattc gtgaccctga gtcaggcaag taccagttgg aaatcagttc
    59701 tgtttatctg gaccacgcgc aaggaattgc ctcccttctc caacagtttt tactggatgc
    59761 caaggtgctt gagcgcaaga agggggctgt gacctatctc cagcgagcag aagacattat
    59821 ggacttcttg atagtaatag gagccatgca ggcacgtgat gattttgagc gggttaagat
    59881 tttgcgagaa acccgtaacg acctcaatcg ggctaataat gccgagacag ctaatatcgc
    59941 tcggacagtt tctgccagca tgaagaccat taacaatatc agtaaaatca aagatatcat
    60001 gggcttagaa aatttgccag tagatttgca ggaagtggcg caactgagga ttcagcaccc
    60061 agactactct atccagcagt tagcagatag tctcagcacc cctctgacca aaagtggtgt
    60121 caatcacaga ctcagaaaaa tcaataagat agcggatgaa ttataaaacc acgaatccta
    60181 tgtgactcgt ggttcttttt tataaactgg tagagtgttt tggttgtact ttttgttcag
    60241 ggtcaatgta gttgatagcg ttgttgacag cagttggagc ttctccgagg cctgtcgcaa
    60301 tcagatcaat ttttccgtca tagtagcagc agtcaccgat agcatagata cctgcttggc
    60361 tggattcctg tttgctgttg acgataatct tgtgacggtt gaggtcgagc ccccagtttt
    60421 taaggttacc gacagaagat ttgaaaccat agttgacaaa gaggtggtct agatcaatgg
    60481 tttcagtttc atcagatttg acttttgtga tttcaagttt atcaagtgtt tttccatttc
    60541 caaggagttg gctaggggcg aatggtgtct tgatggttac agatgattct tgcaaggctt
    60601 gaacactgtg ttccaaggca cggaaattat ctctgcggtg aacaagggta gttggtgcga
    60661 ttttttcaaa agccaaagcc caatccacag ccgagtctcc cccaccaaga atcgtcactt
    60721 tcttaccagc gtattgctga atgttagaaa cgtggtagtg gatattttca tagccctcaa
    60781 ccccttcaag ttccagcgga cgtggtttga aggcaccgcc acccatagcg atgataactg
    60841 ttttagtcag gtgacttcct ttagaagttg tgatggcaaa ttcttcttgt ttgtcaatct
    60901 caagaaccgt ttcattgaga tgaatagggg tatcaaatcc atttagctgt tcaatcaagc
    60961 ggttagtcaa ctcttctcca gtcaggtttg ggaagcctgg tacgtctagg atttcctttt
    61021 cagggtagag aatagcaggt tgtccaccta gctggggaag agagtcgatg atttgaacct
    61081 tggcttggcg taggtgggca taaaaggctg caaaaagccc gacaggacca ccacccacaa
    61141 tggtaatatc atagagttga gacatagttt ctcctttgtt ttttctagtc agtttatttt
    61201 atcatatttt tgttcaatgt aaaatggact aggataggga aaaaaatgcc agaaaatggt
    61261 ataataggac gaaagtgttt tgatagggag gatatcaggg atgaattttc aacaattatc
    61321 caatctgcaa tattggacca gtttgtttgc aagtccatgg acgatagcta tcaatctgat
    61381 tgatattttg attgttgctt atattttata ccattttaca aaagctattg caggaaccaa
    61441 gattatgatt ttggtacgtg gagttttggt gtttatttta gctcaaatcc ttgcaaatat
    61501 gattggtttg actacgattt cttggttaat caatcaaatt attacttatg gggttattgc
    61561 ggcggttgtt atcttctctc cagagattcg gactggtttg gaacgtttgg gaagagcgac
    61621 agatttcttt tccaatgccc ctattagtgc tgaggaacag atgattcgtg cctttgttaa
    61681 gtctgttgaa tacatgagtc ctcgtaaaat cggggccttg gttgctattc agcgtgtacg
    61741 taccttgcag gagtatactt cgacaggaat tcccttggat gctaagattt ctgcagaact
    61801 tctcattaac atttttattc ccaacactcc cctacatgat ggtgcggtga ttatcaaaga
    61861 agaacgtatc gctgtgacgt ctgcctatct gcccttgaca aaaaacacag ggatttccaa
    61921 ggaatttggg accagacacc gggcggctat cggtttatca gaagtctcag atgccttgac
    61981 ttttgtcgta tcagaggaaa cgggaggaat ttcgataacc tataatggaa ggtttaagca
    62041 caacctaaca cttgatgaat ttgaaacaga attacgtgaa atcttacttc caaaagagga
    62101 agtgggtctt agttttaaag aacgattgct aggaggatgg aaacatgaaa aaaaatagtt
    62161 tatatatcat atcctcactc ttttttgctt gtgtcttatt tgtctatgct acggcgacga
    62221 attttcaaaa cagtaccagt gctaggcagg taaaaacgga aacctatact aatacagtaa
    62281 caaatgtccc tattgacata cgctataata gtgataagta ttttattagc ggttttgctt
    62341 cagaagtatc agtggtcttg actggtgcaa atcgcctatc gctagctagt gaaatgcaag
    62401 aaagtacacg taaattcaag gttactgctg acctaacaga tgccggtgtt ggaacgattg
    62461 aagttccttt gagcattgaa gatttaccca atgggctgac cgctgtggcg actccgcaaa
    62521 aaattacagt caagattggt aagaaggctc agaaggataa ggtaaagatt gtaccagaga
    62581 ttgaccctag tcaaattgat agtcgggtac aaattgaaaa tgtcatggtg tcagataaag
    62641 aagtgtctat tacgagtgac caagagacat tggatagaat tgataagatt atcgctgtct
    62701 tgccaactag cgaacgcata acaggtaatt acagtggttc agtacctttg caggcaatcg
    62761 atcgcaatgg tgttgtctta ccggcagtta tcactccgtt tgatacaata atgaaggtga
    62821 ctacaaaacc agtagcacca agttcaagca catcaaattc aagtacaagc agttcatcgg
    62881 agacatcttc gtcaacgaaa gcaactagtt caaaaacgaa ttaaaaatag aaaaggattt
    62941 tataacaatg ggtaaatatt ttgggactga tggagtccgt ggagaagcta acctagaact
    63001 aacaccagaa ttagccttta aactaggacg ttttggaggc tatgttctta gtcaacatga
    63061 aacggaagcg ccgaaagtct ttgtaggacg tgacacacgt atttcagggg aaatgctgga
    63121 atcggccttg gtggcaggtc tcctttcagt agggattcac gtatacaaac ttggtgtcct
    63181 tgcaacacca gcagtagctt acttggttga aactgaagga gcaagtgccg gtgtcatgat
    63241 ttctgctagc cacaacccag cccttgataa cggaatcaag ttctttggcg gtgatggctt
    63301 caaactagat gatgaaaaag aagcagaaat tgaagccttg ctagatgctg aggaagacac
    63361 tcttcctcgt ccaagtgcag aaggcttagg aattttggta gattatccag aaggcttgcg
    63421 taagtatgaa ggataccttg tttcaactgg aactcctctt gatggaatga aggttgcctt
    63481 ggatacagct aatggagcag cttctaccag tgcccgtcaa atctttgcag accttggtgc
    63541 ccaattgacg gttatcgggg aaacaccaga cggtcttaac atcaacctta atgttggttc
    63601 aacacatcca gaagcccttc aagaagtggt caaagaaagt gggtcagcta ttggtttggc
    63661 ctttgatgga gacagtgacc gcttgattgc tgttgatgag aatggtgaca tcgtcgatgg
    63721 tgacaagatt atgtacatca tcggaaaata cctttctgaa aaaggacaat tgactcaaaa
    63781 tacaattgtg acaactgtta tgtctaacct tggtttccac aaggccttga atcgcgaagg
    63841 tattaacaag gcagttactg cagttggtga ccgctacgtt gttgaagaaa tgagaaaatc
    63901 aggttacaac cttggtggtg aacagtctgg tcacgttatc ttgatggatt acaataccac
    63961 aggtgatggt caattatcag cagttcaatt gactaaaatc atgaaggaaa ctggtaagag
    64021 cttatcagag ttggcggcag aagtaacgat ttatccacaa aaattagtta atatccgagt
    64081 ggaaaacgtc atgaaggaaa aggccatgga agtgccagct atcaaggcca tcatcgagaa
    64141 gatggaagaa gaaatggcgg ggaacggccg tatccttgtt cgtccaagtg gaacagaacc
    64201 cctcttgcgt gttatggcag aagcgcctac aacagaagaa gtagactact atgttgatac
    64261 catcacagat gtagttcgtg ctgaaattgg gattgactaa atcctagaaa actagatgaa
    64321 aataaaaaat tatggtacaa tagcttataa tattgtagcc gatggagaaa gacatgaatc
    64381 ttaaacgtga acaagaattt gttagtcagt atcattttga tgcgcgtaat tttgaatggg
    64441 aaaatgaaaa tggagctcct gaaaccaagg tggatgtgaa tttccaattg ctccaacatg
    64501 accaagaaaa tcaagtgact tccttgattg tcatcttgag ctttatgatt gtatttgata
    64561 agtttgtcat tagtggaaca atctcacaag taaatcatat cgatggccgt attgtcaatg
    64621 aaccaagtga attgaaccaa gaagaggtgg aaaccttggc tcgtccatgt ttgaacatgc
    64681 tcaatcgttt gacttacgaa gtgactgaaa ttgcattaga cttaccagga attaatttgg
    64741 agttctaata tgaaattagc tgttttcaca gattcctctg cttatctcag tgcagagatc
    64801 ttgcaaagag aagacttgtt tgtcttggat attcctgtca atattgatgg tgaggaatat
    64861 gtcgaaggca tcaatctgtc tgctgaggaa ttttaccaaa aaatggctca ggcttctgaa
    64921 ttgcctaaga ccagtcaacc aagtattgcc aagttagatg aaatcttaac ttcgctcaaa
    64981 gaacaaggct atacacatgc cttggggctt ttcctatctt ctggaatttc aggtttttac
    65041 caaaatatcc agtatatggt cgatgactat gagggcttaa ccattgcttt cccagacact
    65101 ttgattacaa gtgctcccct aggcatcatg gttgaaaacg tctttaattg gcgtgatcag
    65161 ggcgatgatt ttgccagcat tcaggataag ctagccattc aaatcagccg tacgtcagcc
    65221 tttatcatgg tagatgactt ggatcatttg gtaaaaggtg gacgcctttc aaatggggct
    65281 gccattttgg gcaatttgct tagcattaag ccaatccttt attttaacga tcaaggtgtg
    65341 attgaagttt acgaaaaagt tcgtactgaa aagaaggcca ccaagcgctt aattgaaatt
    65401 atcaaggaaa caacggcttc aggtcaatac cgggtcattg tcattcatgg gaatgctcct
    65461 gaaaaggctg aagaattgcg tcagcacttg cttgattttg gcttgggttc ggatgtttca
    65521 cttgctacat ttggtagtgt cattggaacg cacctaggag caggaagtat tgctctgggt
    65581 tatattccag tgatttagtt ggcgcttcta ggctagttaa gatgccttgt atcttagaaa
    65641 ttgaacacgg actacctgcc tcttgaaaaa agatgcctgt cttgcctttc gtggaaagtc
    65701 agtgccattc cctatttttc agaggcagct aaggtccttt gtatcttgat aattgaacac
    65761 gcctggaacc ctgtgtgaaa aagatagttc ttccaagaag tagacacttc ttgattggaa
    65821 ttcctatttt cactttgtgt tcttacggac tttgtatctt agacaggagt agagatgagt
    65881 attcgagtaa ttattgccgg ttttaaggga aagatgggcc aggctgcttg tcagatggta
    65941 ttgactgatc cagacttgga cttggtagca gtttttgatc cttttgagtc tgagtcagaa
    66001 tggcagggta ttcctgtttt caaggataag gctgatttag ctggttttga agcggatgtc
    66061 tgggtagatt ttactactcc agctgttgcc tacgaaaata cacgttttgc tcttgaaaat
    66121 ggctttgctc cagtagttgg aacgactggt ttcacgagtg aagaaattgc agagttaaaa
    66181 gaattttctc gtgcccaaga cttgggtggc ctgattgccc ctaactttgc cttgggtgct
    66241 gtcttactca tgcaatttgc gacgcaggct gccaaatatt tcccaaatgt ggagattatt
    66301 gagctccatc atgacaagaa aaaggatgct ccgagtggaa cagccattaa aacagctgag
    66361 ttgatggcag aggttcgaga gtccattcag caaggcgcag cagatgagga agagctgatt
    66421 gctggtgctc gtggtgctga ctttgatggt atgcgcatcc actcagttcg tttgccaggc
    66481 ttggtagctc atcaagaagt catctttggc aatcagggag aagggttgac cctccgtcat
    66541 gactcctatg atcgcatctc cttcatgaca ggagtcaatt tgggaattaa agaagttgtc
    66601 aagcgtcatg agcttgtcta tggattagaa cacttattat gagattaacg caaatgcctt
    66661 ctgaatttca gaaggcttta ccagtattag aaaaaattaa agaagcaggc tttgaggctt
    66721 attttgttgg gggctctgtt cgagatgccc ttctccatag ccctatccac gatgtggata
    66781 ttgcgacgtc ttcttatcca gaagagacca agcagatttt tccgcgaaca gccgatatcg
    66841 gaatcgagca tggaaccgtc ttggtcttag atggggatga ggagtatgag gtaacaacct
    66901 ttcggacaga ggatgtctat gtggactatc gcagacccag tgcggtttcc tttgtgcgct
    66961 cgctagaaga agacctcaaa cgccgtgatt tcacagtcaa cgcctttgcc ttggatgaga
    67021 caggagaaat cgttgacttg ttccatggtt tagaagattt ggaaaagcaa gtcttgcgag
    67081 cagttggagt ggctagtgag cgtttcaacg aagatgcttt acggattatg cgtggtttcc
    67141 gttttcaggc tagtcttggt tttgcacttg agccagaaac atttaaagct atgaagacct
    67201 tgacgccgct tttggagaaa atttctgtag agcgtacctt cgtcgagttt gataaactct
    67261 tgctggctcc attttggaga aggggcttgg cttccatgat tgagagtcaa gcttatgact
    67321 atctccctga tatggcatct agccagaaca agctcaacag actgtttgat ttggagactg
    67381 attttacttt tgaatcctct gaacaagcct gggcggcttt actatgggct ttggagattg
    67441 aaaatgcgca gtcatttttg aaatcttgga agacctcacg ccagtttgcc aagcaagttc
    67501 aggatttgct gattattttg gctctgcgtg aaaatggaga attgagcaag cgagattgtt
    67561 atcgctttga catagatttg cttttacagg ctgaaaatct tcgtcaagct cgaggaaaag
    67621 aagtcaaccc acaagccatc acagaaaaat accaaagctt gactatccat gacaagaaag
    67681 agattcagat taatggcgat attttgatca aggaatatgg ctatcagcca ggcccagact
    67741 tgggagagat tttaacagag attgagtttg ccattgtcga tggagaattg gagaataatc
    67801 gtgaagccat ccatgcttac ctgagggaga aaaaatgagt gattttatcg ttgaaaaact
    67861 aagtaaatcc gttggtgaca agaccgtttt tagggatatt tcctttatta tccatgactt
    67921 agacagaatt ggtttaatcg gtgtcaatgg gactggcaag accacccttt tggacgtcct
    67981 ttctggtgtt tctggctttg atggggatgt cagtcctttt tcagctaaaa atgattacca
    68041 gattggttac ttgactcagg atcctgattt tgatgataga aagacagttt tggatacggt
    68101 tctatctagt gaactcaagg aaatccagct cattcgtgag tatgaattga ttatgctcga
    68161 ctatagtgag gacaagcagg cgcgtttgga acgtgtcatg gcagagatgg actctctcca
    68221 agcttgggaa attgagagtc aggtcaagac cgttcttagc aaattgggca ttcaagactt
    68281 atctactcct gttggggaat tgtcaggtgg tctgagaaga cgggtacagt tggcacaagt
    68341 cttacttggc aaccacgacc tcttgctttt ggatgagccg accaaccatc tggatattgc
    68401 gattattgag tggctgaccc tctttttgaa aaattctaag aagaccgtcc tttttatcac
    68461 tcacgatcgt tatttcttag acgctttgtc aacacggatt ttcgagttgg agcgagcagg
    68521 cttgacagaa tatcagggca attaccagga ctatgttcgc cttaaggcag aacaggacga
    68581 gcgcgatgca gctctacttc ataaaaaaga acaactctac aaacaagaac tggcctggat
    68641 gcgcagacaa ccgcaggcac gtgcgaccaa gcaacaagct cgtatcaatc gtttccatga
    68701 tctgaaaagg gaagtttcag gcagtagtgc tgagacagac ttgactatga actttgaaac
    68761 cagtcggatt gggaagaaag tcatcgagtt tcaggatgtt tcctttgcct atgaaaataa
    68821 gcccattttg caagatttta atctcttggt gcaggccaaa gaccgtatcg gaatcgttgg
    68881 ggacaatggt gttggaaaat caaccctact taacctgatt gcaggaagtc ttgagccgac
    68941 agcaggacaa gttgtgattg gggaaactgt tcgcatcgcc tatttctctc agcaaattga
    69001 gggtttggat gaaagcaaga gagttatcaa ttacttgcag gaagtggcag aagaggtcaa
    69061 gaccagtggt ggttctacga cttccatcgc tgagttgctg gagcaattcc tcttcccacg
    69121 ttcgacgcat gggaccttga ttgagaaatt gtcagggggt gagaaaaaac gtctttatct
    69181 cctcaaactg cttttggaaa aaccaaatgt tcttctttta gacgagccaa ccaatgacct
    69241 agatattgca actttgacag tcttagagaa tttcttgcaa ggttttgcag gtcccgtttt
    69301 aacagtcagt cacgaccgct atttcttgga taaggtagcg accaagattc tcgcttttga
    69361 ggatggcaag attcgtcctt tctttggtca ttacaccgac tatcttgatg aaaaagcttt
    69421 tgaaacagat atggccaatc aagtgcaaaa ggccgaaaag gaaaaagtgg tcaaggttcg
    69481 agaagacaag aaacgcatga cctaccaaga aaagcaggag tgggcaagta ttgaaggtga
    69541 tattgaaacc ttggaaaaac gtatcgctgc tattgaagag gaaatgcagg ctaacggctc
    69601 tgactttggt aagctggcta ctctccaaaa agaattggat gagaaaaatg aagcactcct
    69661 tgaaaaatac gaacgctatg agtatctcag tgaatttgat agttaagact attcgaaaat
    69721 caaagtgcaa actatgtcgg cttcacattg ccgactcaag tacagcctgt ggccggcttc
    69781 ctagtttgca ctttgacttt tattgagtat aaaagaatag aaaaatccca tctcatgaac
    69841 ggatttctct attctttttt tgtttcttga tgaaagatat tttgccaggt ttcgtggcga
    69901 cgccagatac tggtatggat gataccatct aactcatagc agatgagttt ggttttttga
    69961 ctgatggaag taatttgaat gtccttgata gcagaattta actctttttt ggtcttataa
    70021 gtctctttat ccatctgctc tccatcttgg cgaatataga caaaatcatc agtcaagagt
    70081 tcttctagtt ggtttccttg gtcaatcaat tgttcacgca taagcaattt tttatagaca
    70141 ttgtctaaaa tttcatcctc agggataggt gctggttcga tatggacatc ggtatcaaag
    70201 acgccaaaac gatcctccag catagactcg acctgatccg cgatttcatg gctttcaaaa
    70261 acagacaagt caggattcat ctctagtgta atatccaggt agatgttgct accgtaggtg
    70321 cgacctcttt gcgatttgac cttgctgatt ttgggaattt ccatgatagc cttttggtag
    70381 tcctcgagca ggcggtcgtc aaagccatct gaaagactaa aggaagactc gatgaagata
    70441 tcataggcag tcttcaagat aaagaaagtg atgatgatag caaccagttt atccacaatc
    70501 ggataattga aactactagc taggatggca atggcggttc caagtgaggt aacagcgtca
    70561 gaaagattgt ccttagcagc tgccttcagc gccttggagt tggatttctt actgaggcga
    70621 gtattgtaga gataaactag aaacataatc gctgcagata taattcctag agttgcaccc
    70681 agaggatcaa tgaccgtttc ttcacgactg agaatcttct gaatggtatc cctcagcaca
    70741 tcaaagccaa cataaaacat gatgatggaa gtgattaagc tagccaaatc ttcaatcttc
    70801 caatggccaa aacggtggtc ccggtctgca ggttggcgcg ccattcgaat gccaatcaag
    70861 agggccacat ttccaatgat gtccgagatg ttgttaaaac catcggccac caaactggat
    70921 gaatgaagaa gatggccagt agccaatttt gctgctgata agagtagata ggtagaaata
    70981 ctgataatgg ccccacgctc agctaacttg agatttgaga tagattgctt cattcaactt
    71041 cctttctagt cacatagcat tctaccatta tactggtttt caagagaaaa ttcaaataac
    71101 taagaagaga ttagaaattg atctcataaa tacttttgtt ttaattagaa aaatatgata
    71161 gacttaataa tggaagaata aattgaaaaa agaggtaata atatgaaaaa tgagaaaata
    71221 actgctttca gtttctcatt atttttagga atcataactt ggtttacatt ggcgacaagt
    71281 gttcgtaaag gtttaccctt attagacgca agtatatttg aatattttgg atatgcaatg
    71341 agtcatggac agagaatgta tttagattta tttgatcata agggaccggt gattttcttg
    71401 attaactatt tgggatatag tatcggagct tctttaggaa ttaaaatatt ataccttgtt
    71461 agtctgatag tttttttcta cattggatat tatatttcga gactttttac aggtataaga
    71521 aattcatgtg ttgttcttgt gattactttt ataatttttg aatctttttt tgaaggcgga
    71581 tggggtttag
//
LOCUS       DAVMBH010000007        55111 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVMBH010000007 DAVMBH010000000
VERSION     DAVMBH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.007"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            129..443
                     /gene="trxA"
                     /locus_tag="VYP30_000522"
     CDS             129..443
                     /gene="trxA"
                     /locus_tag="VYP30_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1807567.1"
                     /translation="MTTQLTTETFAKAIQDGVSLIDFGAQWCPPCRMMEPVVEELSKD
                     FDGKATIAQVDVDQSQDLANLFGIRSIPTMVIFKDGKPVDALVGVHPKQTLMEKIQAQ
                     LS"
     gene            452..1372
                     /gene="trxB"
                     /locus_tag="VYP30_000523"
     CDS             452..1372
                     /gene="trxB"
                     /locus_tag="VYP30_000523"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1807568.1"
                     /translation="MYDTIIVGSGPAGYTAGIYLSRAGLKNRLITGYSEGGQLTTTTL
                     VENYPGFENGIEGNKLVQTMRRQAEQFGTEMTFGFVQKIEGESSPFKVHLDNGEIIDT
                     KAVIIATGSSAKYLGIEGEEEAVGKGVSACATCDAFFYKEREVLVVGGGDVAMEEALY
                     LTRFASKVTVVHRRNELRASDIMVKRAQANDKIHWMLNYTPVKVASNLMGMTGLDVRN
                     NETGDIEHIQADGLFVAIGHQPNTDFLDGKLALDDKGYIQTQAGTAKTSVAGIFAAGD
                     VQDPKYQQAITAAGSGAIAALDTLAYIDNL"
     gene            1369..1638
                     /locus_tag="VYP30_000524"
     CDS             1369..1638
                     /locus_tag="VYP30_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807569.1"
                     /translation="MMDSVTSSIELEELLDEHQNLALLVSGNQCSLSSLGQKELIDTA
                     EREHLVLYQADIFQVPRLISLFGIQPTLTSLLVFKKGQLVDRKEV"
     gene            1639..1818
                     /locus_tag="VYP30_000525"
     CDS             1639..1818
                     /locus_tag="VYP30_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003156488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEV1807570.1"
                     /translation="MARKALIQRKKKAYPVQEYSRCLACGRPHSVYRKFKLCRICLRQ
                     QAYQGVIPGLKKASW"
     gene            1842..2492
                     /locus_tag="VYP30_000526"
     CDS             1842..2492
                     /locus_tag="VYP30_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HEV1807571.1"
                     /translation="MEISYWSDIACPFCYIGASRMKRAMAAVGLNPEDLTMKAYQLNP
                     NAPLETSETMLTEFATSHGMTTEQVKAQFAHMESMGNEEGLRIDMAGIIPTNTFSAHR
                     LIKWSQKYLDKKDHQNFITALYYLYFEEHANIADHSVLLAVISEFDLPQEEAAQVLAG
                     DAFADEVKRDILEAHQSGVQGAPFFVLNNKYGISGAQPYEYMLATLKKIQAEEGAQ"
     gene            2494..2670
                     /locus_tag="VYP30_000527"
     CDS             2494..2670
                     /locus_tag="VYP30_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807572.1"
                     /translation="MIDTPFQLLDSNSEETGLVCGIDGCSIDPSTQPLENTYQPLEKS
                     KKAVIGRTEWKNKE"
     gene            2652..3215
                     /locus_tag="VYP30_000528"
     CDS             2652..3215
                     /locus_tag="VYP30_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HEV1807573.1"
                     /translation="MEKQRVEALSDAILAIIVTIMALELQLPEELTVAGLRSMLPMLF
                     IYITSFLQIMAVWLYYHELYKLVDHVSFHLFGANSFWLLTASFVPLATRGIGQNSANF
                     AFLLFYLIVLALWDVSWIIMTAMVIKTSQRQLSAEEKKIPYRWALLYGLQLVIILLVG
                     YLFPNFIPFAPLLMIINVIYGFLSNKS"
     gene            complement(3365..3583)
                     /locus_tag="VYP30_000529"
                     /pseudo
     CDS             complement(3365..3583)
                     /locus_tag="VYP30_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3764..5230
                     /locus_tag="VYP30_000530"
     CDS             3764..5230
                     /locus_tag="VYP30_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002937371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807574.1"
                     /translation="MFSKLSDHDFKKGVFRTKFSQLVTPLGKESDWAHSKGPEYLWIG
                     LALQYGNRIEQMERVMLALTNLSKALDLEKILPLPAMSLILNLDIDEKKIFVESLNSA
                     FDLSIFSPLSIILPDSEEVLSKNFYSKSHSFNQRLDILVKVLNEVSDQYSQLSTDVRY
                     FLLYYKMLQGKIQFVESQLHMVDGLSKYPYLDISDPEMRIIRPQIRSMEVALSMSEDM
                     NYPYSKRFWNNISQLTDCEVYSIVMDRSNTIDLNKIKDTVFSTLKYYRDMLQSIEPFN
                     EKLYVLTSILTYSYKRLLELMNHGLQYTISGRSIVRSCIENYVMTKYLIAEEEKHKNI
                     WEEYQYYGIGGYKLISERYIENQPELTNSHINFEYLNLLVSEFQNKEFIDMDTRYFGK
                     GNIRQKFEQVEEDDLYKYHYDYDSQFEHGLWGAIRESSILKCNSAGHQFHGIPDIDDI
                     QKLPDVSHDLVMVLTKHLSVIKEVFPIPSEQIEGDSLC"
     gene            5224..6294
                     /locus_tag="VYP30_000531"
     CDS             5224..6294
                     /locus_tag="VYP30_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807575.1"
                     /translation="MLDRLRQSQNEYLELLKRVRWDLDLENVAYHLDKIRNFWFRKQK
                     LLEMCSQYLFNNSNTYFYTAVSKFNVDNSDKNIIFALGNYQIFDDPILSYLEVMEKGN
                     TVHQIERYFKKLKEKIVESIDDLIVLLEKEIPNFYVLPLRFSSSTINKEKVDIRPFIE
                     NFFIEGIDFNNLHKYENIDTVVVHEYLSQILLFDYDDPTQAIKDRLKQYRIEYSDIVP
                     QDMNDTELFQFIVYGYFSQAMDIFLTSYSFNISPFFSSLTTYINYNVFLLNIVHNSKK
                     EKLEHFLKMSRLTLPIWFEYDKKGVELSISEIRERAKNINFSDRIREIYNALDDFNTK
                     EQLITEVENCVHLLINYEGRGC"
     gene            6817..7025
                     /locus_tag="VYP30_000532"
                     /pseudo
     CDS             6817..7025
                     /locus_tag="VYP30_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7181..7519
                     /locus_tag="VYP30_000533"
     CDS             7181..7519
                     /locus_tag="VYP30_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEV1807576.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            7709..9145
                     /locus_tag="VYP30_000534"
     CDS             7709..9145
                     /locus_tag="VYP30_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1807577.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            9197..9436
                     /locus_tag="VYP30_000535"
     CDS             9197..9436
                     /locus_tag="VYP30_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEV1807578.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            9566..9880
                     /locus_tag="VYP30_000536"
     CDS             9566..9880
                     /locus_tag="VYP30_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEV1807579.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            9998..11977
                     /locus_tag="VYP30_000537"
     CDS             9998..11977
                     /locus_tag="VYP30_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1807580.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVEGLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            11987..12301
                     /locus_tag="VYP30_000538"
     CDS             11987..12301
                     /locus_tag="VYP30_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEV1807581.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            12332..12838
                     /locus_tag="VYP30_000539"
     CDS             12332..12838
                     /locus_tag="VYP30_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807582.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
     gene            12918..14264
                     /gene="celB"
                     /locus_tag="VYP30_000540"
     CDS             12918..14264
                     /gene="celB"
                     /locus_tag="VYP30_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEV1807583.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFRSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            14643..14819
                     /locus_tag="VYP30_000541"
     CDS             14643..14819
                     /locus_tag="VYP30_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807584.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            15221..17434
                     /locus_tag="VYP30_000542"
     CDS             15221..17434
                     /locus_tag="VYP30_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HEV1807585.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNMSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(17656..18132)
                     /locus_tag="VYP30_000543"
     CDS             complement(17656..18132)
                     /locus_tag="VYP30_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1807586.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRSKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            18355..21558
                     /locus_tag="VYP30_000544"
     CDS             18355..21558
                     /locus_tag="VYP30_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1807587.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            21938..22314
                     /gene="tnpA"
                     /locus_tag="VYP30_000545"
                     /pseudo
     CDS             21938..22314
                     /gene="tnpA"
                     /locus_tag="VYP30_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(22701..23330)
                     /locus_tag="VYP30_000546"
     CDS             complement(22701..23330)
                     /locus_tag="VYP30_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1807588.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNKKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSALSPAYISAIKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(23340..24341)
                     /locus_tag="VYP30_000547"
     CDS             complement(23340..24341)
                     /locus_tag="VYP30_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1807589.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(24372..25013)
                     /locus_tag="VYP30_000548"
     CDS             complement(24372..25013)
                     /locus_tag="VYP30_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1807590.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(25032..25847)
                     /locus_tag="VYP30_000549"
     CDS             complement(25032..25847)
                     /locus_tag="VYP30_000549"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1807591.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLIGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            26117..26551
                     /locus_tag="VYP30_000550"
     CDS             26117..26551
                     /locus_tag="VYP30_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1807592.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            26563..27753
                     /locus_tag="VYP30_000551"
     CDS             26563..27753
                     /locus_tag="VYP30_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV1807593.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            27764..28255
                     /locus_tag="VYP30_000552"
     CDS             27764..28255
                     /locus_tag="VYP30_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1807594.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            28270..29049
                     /locus_tag="VYP30_000553"
     CDS             28270..29049
                     /locus_tag="VYP30_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1807595.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            29036..29854
                     /locus_tag="VYP30_000554"
     CDS             29036..29854
                     /locus_tag="VYP30_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1807596.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            29854..30147
                     /locus_tag="VYP30_000555"
     CDS             29854..30147
                     /locus_tag="VYP30_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1807597.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            30169..32070
                     /locus_tag="VYP30_000556"
     CDS             30169..32070
                     /locus_tag="VYP30_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1807598.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSENIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            32130..33131
                     /locus_tag="VYP30_000557"
     CDS             32130..33131
                     /locus_tag="VYP30_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1807599.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(33241..33576)
                     /locus_tag="VYP30_000558"
     CDS             complement(33241..33576)
                     /locus_tag="VYP30_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807600.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(33587..33829)
                     /locus_tag="VYP30_000559"
     CDS             complement(33587..33829)
                     /locus_tag="VYP30_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807601.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(33840..34382)
                     /locus_tag="VYP30_000560"
     CDS             complement(33840..34382)
                     /locus_tag="VYP30_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1807602.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(34398..34592)
                     /locus_tag="VYP30_000561"
     CDS             complement(34398..34592)
                     /locus_tag="VYP30_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807603.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEDDF"
     gene            34758..35708
                     /gene="rsmH"
                     /locus_tag="VYP30_000562"
     CDS             34758..35708
                     /gene="rsmH"
                     /locus_tag="VYP30_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1807604.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            35720..36037
                     /gene="ftsL"
                     /locus_tag="VYP30_000563"
     CDS             35720..36037
                     /gene="ftsL"
                     /locus_tag="VYP30_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1807605.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            36041..38293
                     /gene="pbpX"
                     /locus_tag="VYP30_000564"
     CDS             36041..38293
                     /gene="pbpX"
                     /locus_tag="VYP30_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1807606.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            38295..39275
                     /locus_tag="VYP30_000565"
     CDS             38295..39275
                     /locus_tag="VYP30_000565"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1807607.1"
                     /translation="MFISISAGIVTFLLTLVEIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            39884..41989
                     /locus_tag="VYP30_000566"
     CDS             39884..41989
                     /locus_tag="VYP30_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1807608.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRRLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMIG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(42286..42768)
                     /locus_tag="VYP30_000567"
     CDS             complement(42286..42768)
                     /locus_tag="VYP30_000567"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1807609.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(42863..44347)
                     /locus_tag="VYP30_000568"
     CDS             complement(42863..44347)
                     /locus_tag="VYP30_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1807610.1"
                     /translation="MKKQAFSSEQYLNLQRDHILDRINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNRIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTILDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLDINVTFDPYYQYDRLYRK"
     gene            44500..46110
                     /locus_tag="VYP30_000569"
     CDS             44500..46110
                     /locus_tag="VYP30_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1807611.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNEDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            complement(46188..47022)
                     /locus_tag="VYP30_000570"
                     /pseudo
     CDS             complement(46188..47022)
                     /locus_tag="VYP30_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(46970..48355)
                     /locus_tag="VYP30_000571"
                     /pseudo
     CDS             complement(46970..48355)
                     /locus_tag="VYP30_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            48532..49977
                     /locus_tag="VYP30_000572"
     CDS             48532..49977
                     /locus_tag="VYP30_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1807612.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            49979..50710
                     /locus_tag="VYP30_000573"
     CDS             49979..50710
                     /locus_tag="VYP30_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1807613.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            50719..51411
                     /locus_tag="VYP30_000574"
     CDS             50719..51411
                     /locus_tag="VYP30_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1807614.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            51421..52119
                     /locus_tag="VYP30_000575"
     CDS             51421..52119
                     /locus_tag="VYP30_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1807615.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYGSYRKQKK"
     gene            52134..53495
                     /locus_tag="VYP30_000576"
     CDS             52134..53495
                     /locus_tag="VYP30_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1807616.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            53527..54705
                     /locus_tag="VYP30_000577"
     CDS             53527..54705
                     /locus_tag="VYP30_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1807617.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
BASE COUNT        17224 a         9226 c        11831 g        16830 t
ORIGIN      
        1 gaaactaagt gatacaaatt ggatttttag aagggctaag ttaacctttt tgaaattcat
       61 tcttttattc ttatgctatt caattatatg attgaataga agcgatttat tttagatagg
      121 agttttttat gacgacacaa ctaacaaccg aaacgtttgc gaaagctatc caagatgggg
      181 tgagtcttat cgattttggg gcgcaatggt gcccaccttg tcggatgatg gaaccggtag
      241 tggaagaact ttcaaaggac tttgacggaa aagcaacgat tgctcaggtg gatgtggacc
      301 aatcacaaga tctggccaat ctctttggca ttcgttctat cccaacaatg gtgattttta
      361 aagatggcaa acccgttgat gctcttgttg gtgttcatcc taaacaaaca ttgatggaaa
      421 aaatccaagc acagttatca tgaggtgatt tatgtatgat acaattattg taggttcagg
      481 acctgcaggg tacacagctg gcatttattt aagtcgagct ggtttgaaaa atcgattgat
      541 cacaggctat tctgagggtg gtcaattaac caccacaacc ctcgtagaaa attatccagg
      601 ttttgaaaac gggattgaag gcaataaatt agtccaaaca atgcgccgcc aagcagaaca
      661 gtttggcacc gaaatgactt ttggatttgt tcaaaaaatt gaaggcgaat cgtctccttt
      721 caaggtacat ctggataatg gtgaaatcat tgataccaag gccgttatta tcgcaacagg
      781 ctctagcgct aaatacctag ggattgaagg cgaagaagag gctgtcggaa aaggtgtcag
      841 cgcttgtgcg acctgtgatg ctttcttcta taaagagcgt gaagtccttg tagttggcgg
      901 gggtgatgtc gctatggaag aagccctcta tttgacacgc tttgcatcga aagtgaccgt
      961 tgtccaccgc cgcaatgagt tacgcgcatc tgatattatg gtcaaacggg ctcaggcaaa
     1021 tgataaaatt cattggatgt taaattatac gcctgtcaaa gttgcatcta atctgatggg
     1081 aatgactggt ttggatgttc gtaataatga aacaggtgat attgagcaca ttcaggctga
     1141 cggtctcttt gtggctattg gtcatcagcc aaacaccgat tttcttgatg ggaaattagc
     1201 attggatgat aaaggttata ttcaaacaca ggcaggaaca gcaaagacct ctgttgcagg
     1261 tatttttgca gctggtgatg tgcaagatcc aaaatatcaa caagccatta ctgcagcggg
     1321 gagcggtgct attgctgccc tagatacatt ggcctatatt gataacctat gatggattca
     1381 gtcacgtcta gtatcgaatt agaagaactg ttagacgaac atcaaaatct agctcttctt
     1441 gtttcaggaa atcaatgcag tctatcgtct cttggacaaa aagaactcat agacacggct
     1501 gaacgagagc atttggtgct ttaccaagca gatatttttc aagtgccccg tctcatttct
     1561 ttatttggca ttcagcctac cctgacgagt ttattagtat ttaaaaaggg tcaattggtt
     1621 gataggaaag aggtttaaat ggcaagaaaa gctttgatac aaaggaaaaa gaaggcctac
     1681 ccggttcaag aatactcacg ctgtttggca tgcggccgcc cgcattcggt ctaccgcaag
     1741 tttaaacttt gtcggatttg tttacgccag caagcttacc aaggtgtcat tcctgggttg
     1801 aaaaaagctt cttggtagtg gaaagaaagg aaggaaaaaa tatggaaatt agttactggt
     1861 cagatattgc ctgtccattt tgttacattg gtgctagtcg gatgaagcgt gctatggcag
     1921 ctgttggttt aaacccggaa gatttgacaa tgaaagctta ccagctaaat cccaatgcgc
     1981 ctttagaaac aagtgaaacc atgctcacag agtttgctac cagtcacggt atgaccactg
     2041 agcaagttaa agctcagttt gcgcacatgg aaagcatggg aaatgaagaa gggcttcgta
     2101 ttgatatggc ggggattatc ccaaccaaca ctttttcagc tcaccgtctt attaaatggt
     2161 cgcagaagta tttagataaa aaagatcatc aaaatttcat tacggccttg tactatcttt
     2221 actttgaaga acatgccaat attgcggatc attctgtgtt actagctgtt atcagtgagt
     2281 tcgatctacc acaagaagag gcagcgcagg ttcttgctgg agatgcgttt gctgacgagg
     2341 tcaaacgcga tatcttagaa gcccaccaat caggcgttca aggtgcacct ttctttgttc
     2401 tgaacaataa gtatggcatt tcaggtgccc agccttatga atacatgtta gcgacattaa
     2461 aaaaaattca agcagaggaa ggagcacaat aaaatgatag ataccccttt tcaactacta
     2521 gacagcaatt cagaagagac aggtttagtt tgtgggattg atggctgtag catagatccc
     2581 tcaacacagc cgttagaaaa tacctatcag ccattagaaa aaagtaaaaa agcagtcatt
     2641 gggaggacag aatggaaaaa caaagagtag aagccttgtc agatgctata ttggccatta
     2701 ttgttacaat tatggctttg gagttacagt tacctgagga attgactgta gcaggactta
     2761 gaagcatgct acctatgctt tttatctaca ttactagttt tttgcaaatc atggcagtct
     2821 ggctatatta tcatgaactc tacaaattag tagatcatgt cagctttcat ttatttggag
     2881 ccaatagttt ttggctttta acagctagtt ttgttccctt agcgactcga gggattggac
     2941 agaattccgc taattttgcc tttctcctgt tttacctcat cgttcttgcc ctttgggatg
     3001 tatcttggat aatcatgaca gcaatggtga tcaagacgag tcaaagacag ttatcagctg
     3061 aagaaaaaaa gataccttat cggtgggcac tattatatgg attgcagcta gtgatcatat
     3121 tattagttgg ttatcttttt ccaaatttca ttccttttgc tccgctactg atgattatta
     3181 atgttatcta tggtttttta agcaacaaat cttgaaaaat actaaaaata atggctaact
     3241 agcatcggtt ataaaaacta ggtcttaaga aagctcgtaa agcatcacaa tttagtaaac
     3301 gttaaaactt atttatattt attgaaagca tttcgtatca aaaatacggg atgctttttc
     3361 tgttcacccc aaatatttga accttgaact tccgtgaata ggttccatta cgactattac
     3421 cagaattata gactacttta tcgtaaggtt catactctaa aagggctgat aattctgctt
     3481 taagcaggtc gttcatagct gtttcaagag cagaacgaaa aaattcattg atatctcgtt
     3541 ttttgactag gaagttaaga aattctgtgg taaactgtgt catagaagta aatctctttc
     3601 tagtaatgtt tcgcaactct actataacgg atttattcct ttttgtgttt acacaactta
     3661 ttttacacta cctggtcgaa taacattaga aacgaatgtc ttttatgttc gaggtatagc
     3721 acaatagtgg gaatacaggt agtattgtac tgagaggtat cttatgttta gtaaactaag
     3781 tgaccatgac tttaaaaaag gagtctttag aacaaagttc agtcaattag taactccatt
     3841 aggaaaagaa tctgactggg ctcattcaaa aggtccagaa tatctttgga ttggattagc
     3901 tctgcaatat ggaaatcgaa tagagcaaat ggaaagagtg atgttagctc tgactaattt
     3961 atcaaaagca ttagatttag aaaaaatctt gcctttaccg gcaatgagtt taatacttaa
     4021 tttagatatc gatgagaaga aaatttttgt tgaatcacta aattctgctt tcgacttatc
     4081 aatattttct ccgctttcaa taattttgcc tgatagcgaa gaggttttga gtaaaaattt
     4141 ttacagcaag agtcactctt ttaatcaaag actagatata cttgttaaag tactaaatga
     4201 agtatctgac caatatagtc aattatcgac ggatgtaaga tattttttac tgtattacaa
     4261 gatgttacag ggaaaaattc aatttgtaga atcgcagtta cacatggtag acggattaag
     4321 taagtaccct tacttagata tatcagatcc agaaatgaga attattcgtc ctcagattcg
     4381 ctcaatggag gtagctttat caatgtccga agatatgaat tatccttata gtaaaagatt
     4441 ttggaataat attagccagc taactgattg tgaggtatat tcaattgtta tggatagaag
     4501 taatactata gatttgaata agataaaaga tacagtattt tcgacattaa aatattacag
     4561 agatatgctt caaagtatag agccttttaa cgagaagctc tatgttttga ctagtatcct
     4621 aacctattct tataagcggt tactagaatt aatgaatcat ggtttgcaat atacgatttc
     4681 aggtcgttcc atagtaaggt cgtgcattga aaactatgtg atgacaaaat atttaattgc
     4741 cgaagaagaa aaacacaaaa atatttggga agaatatcaa tattatggta ttggtggata
     4801 taaactgatt tcagaacgct atatagaaaa tcaacctgaa ttaacaaact ctcatattaa
     4861 ttttgaatat ctgaatttac tagtatctga atttcaaaat aaagaattta tagatatgga
     4921 tactagatat ttcggaaaag ggaatataag acaaaagttt gaacaagttg aggaagatga
     4981 tttatataaa tatcactatg attatgattc tcaatttgaa catggacttt ggggagcgat
     5041 tagagaaagc tcaattttga aatgcaactc tgctggacac caattccacg gtattcccga
     5101 tatagacgat attcaaaaat tacccgatgt tagtcatgat ctggtgatgg ttttaacaaa
     5161 gcatctatca gtgattaaag aagtgtttcc tattccaagt gagcaaatag aaggtgatag
     5221 tttatgctag atagactaag acaatcacaa aatgaatatt tagagttact gaagagagtt
     5281 agatgggact tggacttaga gaatgtagct tatcatttag ataaaattag aaatttttgg
     5341 tttagaaaac aaaaattatt agagatgtgt agccaatatc tctttaataa ttcgaacaca
     5401 tatttttata cagcagtttc taaatttaat gtagataact cagataagaa catcatcttt
     5461 gcattaggga attatcaaat atttgacgat ccaatactat cctatttaga agtaatggaa
     5521 aaaggaaata cagtacatca aatagaaaga tacttcaaaa aattaaaaga aaaaattgta
     5581 gagtcaatag atgatttgat agttttatta gaaaaagaga ttccaaattt ttacgtatta
     5641 ccactaagat tttctagttc aactatcaac aaagaaaaag ttgatatcag accgtttatt
     5701 gaaaacttct ttatagaagg cattgatttt aataatttac acaagtacga gaatatagat
     5761 actgtggtcg tacatgaata cttatcgcag atattactct ttgattatga tgatcctaca
     5821 caagcgataa aagaccgttt aaaacaatat cgaattgagt actcagatat agtcccacaa
     5881 gatatgaatg atacagaact tttccaattt attgtctatg gctatttcag tcaagctatg
     5941 gatatttttc tgacttccta ctctttcaat atttccccat tcttttctag cttaactaca
     6001 tacataaatt ataatgtttt cttattaaat atcgtgcaca attcgaaaaa agaaaaacta
     6061 gaacatttct taaaaatgtc aagattaacc ttacccattt ggtttgaata cgataaaaaa
     6121 ggagttgagc taagtatttc tgaaatacgt gaaagagcaa aaaatataaa cttttcagat
     6181 cgtataagag agatttataa tgctctcgat gatttcaaca ccaaagagca gttgattact
     6241 gaggttgaga attgtgtaca tttattgata aattatgaag gtagaggttg ctagtaatgt
     6301 tgtttctcaa taacataagc tccgaaaact aaaaaaatga taaccctttg ataacctctc
     6361 gatttttaaa agggttatat atgtaaagat cgaggattta tctcttaaaa ttacttgatt
     6421 ttagtgataa tttaccataa atatcataat gtagaaaaaa ccaggtctta agaaagctcg
     6481 taaagcatca caatttagta aacgttaatt cgaaagaatt actatactta tacagagcac
     6541 ctttcggggt gttctttttt atactttctt actaaattgg tgcaattgac acagttgttg
     6601 cgactttagt cgcttacaaa tgtggctgca acctgacaag gtcagttgcc tcaaaacgtt
     6661 aatcaatacg attatatcaa cgtttcaaag cactcaaaag tttaccttat ttttatagta
     6721 atgtgaaata agaataggac aaaccgagga taatcaaatc gaattctaac aatgttttag
     6781 aagtagaggt gtactattct agtttcaatc tactatatta tggataatgc aagattccat
     6841 agaatgggta agttagaact cttgtgtgaa gagtttgggt ataaacttta acctcttcct
     6901 ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
     6961 aaaaaggtat tacaagttgc aatacctttt atgaggctct tttgtcttgt tctagtttca
     7021 attgactata aatcgctata agaaaaaatc attttattgg tataaagaag tgattgaaag
     7081 taatggcaaa acgttagata attagttcat aaaaaacaag tttagatcct catctaaact
     7141 tgttttttta aaattgaagg atgattttgg aggatataag atgacattga ctattcatgt
     7201 atattataaa ggtgatggag atagtgcaat aaagtttgca agagaaatgc ttgatagtgg
     7261 ccttgttgaa gaaattagaa atcaaaaagg taacttgaaa tacgaatatt ttttaccaat
     7321 tgaaaaagag ggaactattc tccttattga tcagtggata aatcaagaaa ctttagataa
     7381 acattatcaa tcaaagacaa tgcagaaaat cttagattta agaaaaaaat atcacttgca
     7441 gatgcaagtt gaacgttata tagaagatga ttctgggatg ccagaaagcg ataagtcgtt
     7501 tatagacaca gggaattaga attattgtga gagtttttgt agtttgaaag tattgaaaat
     7561 cgtaaagata tcattacgag aatacaagaa gatattgttc tatttccatt aaaaattact
     7621 tctttcctta acaataagga aaaagaatac gttttcattt tttggtttga ggtttataat
     7681 aagagtatca aagtcaggag gaaaaaagat gactactttt aaagatagat ttttatgggg
     7741 tggtgctgtt gctgctcatc aacttgaagg cggatggcaa gaaggtggca aaggaattag
     7801 tgttgctgat gttatgactg ctggtcgtca tggagtagct cgtgaaatta cttcgggagt
     7861 tttagagggt aaatattatc caaatcatga ggcgatagat ttttatcatc gttataaaga
     7921 agacatagca ctttttgctg aaatgggatt caagtgcttc cgtacctcta ttgcatggac
     7981 acgtatcttt ccaaaaggtg atgagttaga gccgaatgaa gaaggattac agttttatga
     8041 taatcttttt gatgaatgct taaagaatgg tattgaacct gtcatcactc tatctcattt
     8101 tgaaatgcct tatcacttag tgaccgaata tggtggttgg aaaaatagga aattgattga
     8161 tttctttgct cgttttgcag aagtcgtatt taaacgttac aaagataagg ttaaatattg
     8221 gatgactttc aatgaaatca ataatcaagc gaattatcag gaagattttg caccatttac
     8281 taactcaggt attgtatatg aggaaggtga taatagagaa gcaattatgt atcaagcagc
     8341 acattacgaa ctagttgctt ctgcacgagc tgtaaaaatt ggtcatgaga ttaatccaga
     8401 ttttcaaata ggttgtatga ttgcgatgtg tccaatttat ccagctactt gcaatcctaa
     8461 ggatatctta atggcaatga aagctatgca gaagcgttat tattttgctg atgtgcatgt
     8521 tttaggtaaa tatcctgagc atattttcaa gtattgggaa cgaaaaggta tttcagttga
     8581 ttttactgac caggataaag aagatttact tggtgggact gtagattaca ttggtttcag
     8641 ttactatatg tcctttgcta tagactctca tcgtgaaaat aatccttatt ttgattatct
     8701 tgaaacagaa gatttagtga aaaataatta tgttaaggct tctgaatggg agtggcaaat
     8761 tgatccagaa ggtttacgtt atgcgttaaa ttggtttaca gaccactatc acttaccact
     8821 ctttattgtt gaaaatggtt ttggagctat agatcaagtt gcagcagatg gtatggtaca
     8881 tgatgattat agaattgaat atctaggtgc ccatattcgt gaaatgaaaa aggctgtagt
     8941 tgaagatggt gttgatttaa tgggttatac tccatgggga tgtattgatt tggtttcagc
     9001 tggtaccggt gaaatgcgga aacgttatgg ctttatttat gtagataaag atgacaatgg
     9061 gaagggaagt tataatcgtt ccccgaaaaa atcttttggc tggtataagg aagttatttc
     9121 atctaacggt gaatcagtag aatagtataa acaaactgag attattctca gtttgtttag
     9181 catattgagg tgacatatga ttggaagtat tgcagcaatt ttaacaacat ttgcattttt
     9241 accacaagtt tttcgtgtag ttaagacaaa ggacacagga tctattgctc taggtatgta
     9301 tgttatgcag gttattggta ttgcattgtg gcttgctcat ggtattcgta taggagactt
     9361 gcctttgatt ttagcaaata gtgtttcatt tctactctca ggaataattt tattttataa
     9421 attgaagtat aaataatttt tttccatatc atttaggaaa atgagggaat tgtcattgga
     9481 aacgctttat tttataataa aaatagataa caaataagcc aacttagcac agctttgatt
     9541 ggatttaaga aaaggagaaa atattatggc aaaagcttta attatttgtg cagcaggaat
     9601 gtcttcatca cttatggcac agaaaacaac agagtttcta aaaggaaaag ggaaagatat
     9661 tgtagttgat gctattagtg ctactgaagg agggaaagct atcgcagcag cagcttttga
     9721 tttgtatctt gtcagccctc aaacaaaaat gtactttaag caatttgaag aggctggttc
     9781 taaagcagga aaaccagttg tacaaatacc tcctcaagca tatattccta ttccaatggg
     9841 aattgaaaaa atggctaatt tgattcttga gaatatttga tgaacacatg aaatgtcaat
     9901 aaatatttag gttaagataa attgttttga gtttgatata aactgattta agtgtataat
     9961 atgcttcaat atatgaaaac atacgtttta ggagggaatg aatgtgttaa acattaaaga
    10021 gaaagatatc cttcaatttt taataaaaaa taaggaacgt tttgttacaa gcaaagaact
    10081 ggcagaatat ttatcctgtt cagatagaac tgtccgtaat gtactgaaat taattgagaa
    10141 gacaatgatt attcaaggag tccggttgat ttcaaaacaa ggtcaagggt atcaaatatt
    10201 ttttgagaat caaggcgctt accaggagtt tagacaaact tatgaactgg aagaagacta
    10261 tacgaaaact gcggtttcaa aaggtgatga tcgtttagta tttatcttaa ataaattatt
    10321 atttgagcaa gttccagttc tttttgatga tttagctgat gaactttacg ttagtcgttc
    10381 aacattatct catgatttca gaaagatacg agtgatgtta tcagagtata atttgtccat
    10441 tgagagtagg gcgaataaag gagtttatgt ctcaggcgag gaacgtgata aacgacgttt
    10501 tatcataaat tatttcctag agaatcaatt ttttaaaaca atacattgct atgtaaaatt
    10561 taactttttt gatcaaactg ttccattaga agaatttgct agaattgttt tggatgaatg
    10621 ccaagaggcc aacctaaaac tatctgattt tgtactacag aatttagtag ttcacatagc
    10681 attgtctgtg attcgtttaa aatccggatt tgaaataaaa aatatagact gtcagatgac
    10741 tgatgatgca atagagagaa aggttgccca aagaattctt tctaaagtaa gagaagtaac
    10801 aaatcaggaa tttccagttc aggaaataga ctacattact ttgcatttgt tagctaagag
    10861 tcaacaatgt caaaaaaatc agaagaatat ttctgaagaa gttttaaaaa aatctttatt
    10921 taaaacattt cagaatttag gattagatga tatgtataac ttttcttcag atttccaact
    10981 aattgaagga ttgataactc atctaatgac actacaagta cgtttagaaa gccggattac
    11041 cttaaataac cctttggtag atgaaattaa acagaattat agtgatatat tctttatgac
    11101 tagagaaatt cttgcaaata tggacaagtt cttggagtgg acaatatcag atgatgaagt
    11161 agcatatgta agtcttcact ttttagctgc tatggaacgt agcaaagaga gtactaagtt
    11221 taatattctt gctatttgtg caacaggatt tggtgcagcc caaatgttaa gaaatcgttt
    11281 ggaaacggag tttgggaagc gagtagaagt tgttgatgta ataggctatt atgaattgaa
    11341 tcaagaaaaa cttaaaggaa tagattttat agtgtcagct gttgatttat caaatctata
    11401 ttttcaaatc ccagttttta aagttagtgt gtttcttaag agtgatgaga tggaaatgat
    11461 tagaaaagct atggatcaga tgcaagtttc tagttatgta caatcatcaa agattaacaa
    11521 atttgaaaac aacggcttta gacagtattt tagtaaagaa aattttttaa tatgtactga
    11581 atcagacaag gtaaatttac ttgaaaagat ggttgagggt ttatctgttg gtgaatcaaa
    11641 tgagtttgaa caatctttac tttatggaat taaacagcgc gaagaattaa gttcagttgt
    11701 tttttctgaa aaaattgcag ttccgcatcc tattcagccc tttggtacag agggaaaggt
    11761 ttcggttgca atctgtaaag attcgttact ctgggataat caaagttcac atgtccagct
    11821 agtatttctt ctatctccat caatatatgg gaacgaaggt ttggcaactg tgactaaaaa
    11881 gatagtctct ctgacagaga atgatgaatt gcaaaatcag ctaatatctt gcaataactt
    11941 tgaagatttt attaacatat ttgagaagat aaaataggag gttcatatga atcaagagga
    12001 actgcaggtt gcagcatttg aaattatcct gcattcggga aatgcaaggt cagaaataca
    12061 tgaagcattt gcaaaaatga gagaaggtag ttttgatgat gcagaaagta aattaaatca
    12121 atcaaatgag ataattcttg aagcgcatca tgcacaaacc aaactcttgc aagaatacgc
    12181 aagtggagtg gaaattaaaa ttgaaattat catggtacat gctcaagatc atttaatgac
    12241 cactatgaca ttattagaag tagcaaagga aatgttagct ctttataaga aagttaacta
    12301 aatatgtgtt gttatataag gaggaaatga tatggataaa aaagaacgac aaaaaattga
    12361 acaacaacgt cgagagatgg ctctaactaa tacttttttt aatcgatatc ttcttctacg
    12421 ttattcaata gcactcttct tttttgggaa tatttattgg cttttgaatc agtttattaa
    12481 tccctcgcct attattattt tccccattat gctcatagta ttttctattt tagcaactat
    12541 tgaacaattt aaactttatg gaaataggaa agaaaagttg ggaataacac taatgtttgt
    12601 tagaatacaa atgcttattt caataggatt acttgtttta acttggacaa gttggtttaa
    12661 gaatcttttt ccgatttttg aaaataacca agtagcacgt ttatttgttt ttgtagttct
    12721 tctattaggt ttagttctga gtttgttaga cattagaaga attaaaaaaa tttataaacg
    12781 aacagataag gtttatcaac aatttgtcca attggaaaag aactcactta gtttataatc
    12841 ctgatctagt ataatttgta tttgaaacta gtctttagaa agtaaaaatt attatgtttt
    12901 attaaggagg tctatttatg gatcaacaaa acgggttgtt tggttttctt gaaaaccatg
    12961 ttatgggacc aatgggcaaa cttgctcagt ttaaagtagt acgtgctatc acggctgcag
    13021 gtatggctgc tgtaccattt actattgtag gatcaatgtt tttggtattc agtattttgc
    13081 cacaagcttt ctcattttgg ccaattgtgg cagatatttt ctctgcttca tttgataaat
    13141 tcagatcact ttacatggtt gcaaactatg cgactatggg ttctctatct ctttatttcg
    13201 ttctatcact tgcatatgaa ttgacaaaaa tttatgcaga ggaagaagaa ctcaatatga
    13261 atcctcttaa tggtgccttg cttgccttga tggcttttgt catgacagta ccgcaaatca
    13321 tttttgatgg tggaatgatg aagactgtga caagtctaaa agaaggtgca gtaattgcag
    13381 atggatgggc aatgggaaat ggagtcgcac gttttgggac aacagggatt tttaccgcaa
    13441 tcattatggc aattgtgact gttcttattt atcgtatgtg tgttaaacat aattgggtta
    13501 ttaaaatgcc tgaagctgtt ccagaaggag tttctcgtgg atttaccgct ttggttccgg
    13561 gatttgttgt tgcatttgtt gttatcttta tcaacggtct tcttgtagca atgggaacag
    13621 atatttttaa agtcattgca attccatttg gttttgtatc caatctgact aattcgtgga
    13681 ttggtttaat gattatttat ctattgactc aactactttg gattgtaggt atccacggtg
    13741 cgaacattgt ttttgcattt gttagtccaa ttgctcttgc caacatggct gaaaatgctg
    13801 ctggcgggca cttcgctgtt gcaggtgaat tttctaatat gtttgtaatt gcaggtggtt
    13861 ctggtgcaac tttaggacta tgtttatata ttgcttttgc ctctaaatct gaacagctta
    13921 aagcaatagg acgagcatct gtagttccag ccttatttaa tattaatgaa ccattaattt
    13981 ttggattacc tattatctat aatccagcct tggctatacc atttatttta gcaccaatgg
    14041 ttactgctac tatttattac gtagcgaatt ctctaaactt tattaagcca attatcgcac
    14101 aggttccatg gccaactcca gtagggattg gagctttctt agggacagca gatcttcgag
    14161 ctgtattagt tgctctagta tgtgcatttg cagcattcct agtctatctt ccattcatcc
    14221 gtgtatatga tcaaaaattg gtgaaagaag agcaaggtat ctaataagta aaaaagtata
    14281 ctcgatgata gaatccatat agtttaaata atgagcgtta acattagcag tgaagaggtc
    14341 tttttaagat attcttctct gttttttcat attttttcgc tatgtagggt atgaagcaaa
    14401 atagaaagta gttcgaatag ttgataaaca gggaactgct gttatttaaa aaaacaataa
    14461 agtaaagtat gttatcgtag aatacgatac aatagtaaaa aagcaaaaag aatgcgtttt
    14521 atatttgggt ttgaggttta taaaatagga taagcgtgct gaaaacttag atatgacaaa
    14581 caaaataaaa tttttaaaag ctacagagaa acatggtata atgtatctaa aggaggtagc
    14641 atatgtcctt agatatagat aaagaaaaga tgacaatcat gggaatagct tttgaaaacc
    14701 gatccgtttt taagagtgtt tggtatgctt taagtacaaa tatgattgaa ggatggcgac
    14761 ctacggttag tgatgttgaa aaattacgag atgaagctct tgctctgggg atgacttaat
    14821 gaagcgcaac tgttacgagt cttatgacta tgttgatccg gataatttat ataccgatcc
    14881 gggttcttca gttctaagaa ataagcagga aggaaaaaag cacgtgagct tgaatatcgt
    14941 atgattgcta gtaagagttt gaaattattt atcaatccta tcttagttaa tagtttaaaa
    15001 gtagtttgtt tcacaactgc ataagcttag aaaagttgaa aagtgataac tctttaataa
    15061 actcttggtt tgttaaaaga tattttgtcc actacatttt tttcaattga ctattatttg
    15121 tcatagatat aacagataga acattgcatt cagaataatg aaaaacgcat caaaaatggt
    15181 gcgttctgtt tttatgctac cataaaagga ggaaaacaaa ttgaaaattt ttaagggaga
    15241 gttttatcga atctctgtat taacagacaa gctagtaagg ttagaatact ctcaaactgg
    15301 aagttttgag gatagaacga cacaacttat ctataataga gattttggcc aaatttcgtt
    15361 agattatatc gagacatcaa acgtactaga tattatgacg gactattttc atctgcactt
    15421 taataaagga gaatttaacg ccgaaaattt atttatagaa ttaaaaggaa attttgccgt
    15481 atatggtagt cgctggtatt ttggtgaatc tattgaaacg ttaaaaggaa cagctcggac
    15541 tctggataag gcagatggag caatctcgtt agaagatgga attattagcc gaaatggtat
    15601 agccttattg gatgattctc aaggatttat ttgggatgaa caatctggtt atattgagag
    15661 agaaaatcaa attgacctgt atttctttgc ctatgggcat gattatagag gagcaatcag
    15721 agacttttac catttgactg gttcaacacc cttgttgcca agatatgctt taggcaattg
    15781 gtggagtaga tattggcctt atacgtcgga tgaatacttg gatttaatag acagatttga
    15841 aacagagaaa attccattat ctatcggtgt gttagatatg gattggcata taactgacat
    15901 tccagctcgt tttggaagtg gctggacagg atatagttgg aatagaaact taataccaaa
    15961 tccagaacag ttattgcaac aacttcatga tagaaagtta aaactctcct taaatgtcca
    16021 tcctgctgat gggatacggg cttatgaaga agcttatcct caaatcgcaa aacgattggg
    16081 gttaaatgta gaactagaag aacctgctat ttttgatttt tttaatccct cttttaggga
    16141 agcctacttt aaagatgttc attatgagct agaaaagcag ggagtagatt tttggtggat
    16201 tgactggcaa caggggacac aaggcatgct agatccactt tggcttttaa accattatca
    16261 ctatcaggat agttgtaaaa atgcagaagg tggtttgatt ttatcaagat atgcaggtcc
    16321 tggtagtcac cgctaccctg ttggtttttc aggggatact attattagtt ggaattcctt
    16381 aagatttcaa ccctatttta cagcgacagc atctaatatc ggttatagtt ggtggagtca
    16441 tgatatcggt ggacatatgt tgggggatta tgacgaagag ctacaaacta gatggctaca
    16501 gtttggtgtt tttagtccga ttactcgatt acatagttct agaagtcctt ttaatagtaa
    16561 agaaccttgg ttcttttcag aaacaacatc taagattatg aagaaatacc ttcgtttgag
    16621 acatcagatg attccctatc tatataccat gaatgtacag acacatgagg aaggtgcccc
    16681 attaatcagt ccaatctatt atttctatcc agagaatgat gagagctata atgttccaaa
    16741 ccaatacttt tttggaacag aactgatggt ggctcccatt gtagaaaaga tggatttgac
    16801 attccaatct gcaaaagtag atgtatggtt ccctgaaggt gaatggtatg acttcttttc
    16861 agagaaaaaa tacacaggtg gtgtgaagtt aagtgtttat agggacatct cgactacgcc
    16921 tgtgtttgca aaaagtggtg caatcattcc cttggttggt tctgagatag gtatgggtgt
    16981 tgatttacct gaggttgtag attggtatgt attcccaggg aaacaacatt tttttgaaat
    17041 gcttgaagat caaaatggtc aaagatataa aacaagatta tcaatcgatt gggaaatggg
    17101 aatggtagag ttagcattac aaggagattc tagtatcgtt ccaagcaata gaaaacatag
    17161 aattcatttt aaaggaacga atatgtctat aattgaattg ccaaataaga atgatacagc
    17221 taaatttgaa tggaaagata ataaaaggac atctttaaat gacgaagttt ttagactact
    17281 aaagacagct tctcttccat atgaattaaa agatagattg ttaaatcaat tcatcaatgc
    17341 gaaaaactct catgacttaa tgaatatctt gcatcatcag gataaggaat tgagagggcg
    17401 tttgttggaa atgatattta ctagccaaaa ctaattgaaa taattagaaa gtcatttgtt
    17461 tagtgtatat gaagattctg tatggtattc gttatcactg gtcacattga aaatgtgaaa
    17521 taagcaccta caacatagac tttacaacac ttcatgtttc atatcatggg gtgtttttct
    17581 atttaagtca aagcccatca aaaaatctca ctattcatca ggttaaagga aacctaatca
    17641 tagtgagatt gtgaattata gtagagtttg tatcgcctct tcaatttgtt ttgggtctgt
    17701 ttttgaagaa aagcgttcaa agacttgccc atcacgacca atgagaaact tagcgaaatt
    17761 ccattcgatt cgttttccta gtgggccaga tttatggtct tttaaccaga catagagagg
    17821 gtctgcttcc ttaccgttga ccttaatctt ggcaaaacgt gggaaggtgg tttgaaaatg
    17881 taggctacag aaggcgttga tttcctctgc gctgccgggt gcttgtccca taaactgatt
    17941 gcaagggaaa tccaatattt cgaagccctg atcttgatag cgttcataga gttcttgaag
    18001 tccctggtac tggggcgtta aaccacatcc agtagcagtg ttgacaatca agagaacttt
    18061 gctacgatag ctatccaagg gagttgcttg gttgttttgg ttcaaaacgg aaaaatcata
    18121 aagtgaagtc atgagggcct cttttctttt tctacattgt aacagttttt acttttttcg
    18181 tcgagtcgga tggaagatat tgttgaagaa taagccctca atatgataga aatcgtttac
    18241 aaataacttt aaaaatggta tgatttaact aaaccggttt acttagttgc tataaatctc
    18301 taatttgaga tttagttcct attgatttta caatatgttt attggagtgt atacatgcaa
    18361 acaaaaacaa agaagctcat tgtgagtttg tcttcacttg ttttatcagg atttttatta
    18421 aaccattata tgacagttgg agcggaagaa acgactacga ataccattca gcaaagccag
    18481 aaggaagttc agtatcagca aagggataca aaaaatttag ttgaaaatgg tgattttggt
    18541 cagacggagg acggaagcag ttcgtggaca ggaagcaaag ctcaggggtg gtcagcttgg
    18601 gtagaccaga agaatagttc tgcagatgcc tcaactcgag tcattgaggc taaggatggg
    18661 gctatcacta tctcaagcca tgagaaatta agggcagcgc ttcaccgtat ggttcctatt
    18721 gaagttaaga aaaagtataa actgcgtttc aagattaaaa cagataataa aatcgggatt
    18781 gccaaagttc gtatcattga ggaaagtggt aaggacaagc gattgtggaa ttctgcaacg
    18841 acgtcaggaa caaaggactg gcagaccatt gaagcagact atagcccgac tttagatgtt
    18901 gataaaatca agctggagtt attctatgaa acaggaactg ggactgtttc ctttaaggat
    18961 attgagctgg tagaggtagc agcccagctt tctgaggatt ctcaaacaga taaacagctt
    19021 gaggaaaaga ttgatttacc aattggaaaa aaacatgttt tttctcttgc ggactatact
    19081 tataaggtag aaaatcctga cgttgcttca gtcaaaaatg gaattttaga acctcttaag
    19141 gaagggacaa ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa gattcctttg
    19201 aagattctag cctctgttaa ggatacatac acagaccgtt tggatgactg gaatggcatc
    19261 atcgctggga atcaatacta tgattctaaa aatgaacaga tggccaaatt aaaccaggaa
    19321 ttggaaggaa aggtagctga tagcctatcc agtatttcaa gtcaggcgga ccgcacctat
    19381 ttgtgggaaa aattttcaaa ttataaaacg tctgcaaatc tgactgccac ttatcggaaa
    19441 ttggaggaga tggccaagca agtgaccaat ccttcttctc gttattatca agatgaaact
    19501 gtcgttcgaa cagtcaggga ttccatggaa tggatgcata aacatgtcta caatagtgaa
    19561 aagagcattg ttgggaactg gtgggattat gaaatcggta cacctcgtgc catcaacaat
    19621 accttgtctc tgatgaaaga atacttctct gatgaggaaa ttaaaaaata tacagatgtg
    19681 attgaaaaat ttgtaccaga tcccgaacat ttccgaaaga cgactgataa cccatttaag
    19741 gctctaggtg gaaacttagt tgatatggga agagtaaaag taatagctgg tttactgcgt
    19801 aaggatgatc aagaaatttc ttctaccatt cgctcgattg agcaagtgtt caagttggta
    19861 gaccaaggtg aaggttttta tcaagatgga tcctatatcg accataccaa tgttgcctat
    19921 acgggtgctt atgggaatgt tttgattgat ggcctgtctc aactgttgcc agtcattcaa
    19981 aagaccaaga atccaatcga taaagataaa atgcaaacca tgtaccactg gattgataaa
    20041 tcgtttgctc ctttgctggt gaatggagag ctgatggata tgagtcgtgg acgctcgatc
    20101 agtcgtgcaa atagcgaggg gcacgtggcc gcagtagaag tactaagagg gattcaccga
    20161 atagcggata tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt gaagaccatt
    20221 gttcaatcgg atagttatta tgatgtcttt aagaatttga agacttataa ggatatcagt
    20281 ttgatgcaat ccttgttaag tgatgcagga gtcgcaagtg ttccaagaac aagttaccta
    20341 tctgccttta acaagatgga taaaacagcc atgtacaatg cagagaaagg gtttggattt
    20401 ggcttgtcac tcttttccag tcgtaccttg aattacgaac acatgaacaa ggaaaataaa
    20461 cgtggttggt atacgagtga tgggatgttc tatctttaca atggcgattt gagtcactat
    20521 agcgatggct actggccaac agttaatcca tataagatgc ctggtacaac agagacggat
    20581 gctaagagag cggatagcga tacaggtaaa gttttaccgt ctgctttcgt tggaacgagc
    20641 aaactagatg atgccaatgc gacagcaacc atggatttca ccaactggaa tcaaacattg
    20701 actgctcata agagctggtt tatgctaaag gataagatcg cctttttagg aagcaatatc
    20761 caaaacactt caacagatac tgctgcaact acaattgacc agagaaaact ggaatcaagt
    20821 aatccatata aagtctatgt caatgataaa gaagcctccc ttacagaaca agaaaaggat
    20881 tatcctgaaa cccaaagtgt ctttttagaa tcatccgatt cgaaaaagaa tattggttac
    20941 tttttcttta agaagagttc aatcagtatg agtaaggctt tgcaaaaggg agcctggaag
    21001 gatatcaatg aaggacagtc agacaaggaa gttgaaaatg aatttcttac gattagtcag
    21061 gctcataagc aaaatggaga ttcttatggc tatatgctca tccctaacgt gggtcgtgcc
    21121 accttcaatc aaatgataaa agagttagaa agtagcctca tcgaaaataa cgaaaccctt
    21181 cagtctgttt atgatgccaa acaaggagtt tggggcattg tgaaatatga tgattctgtc
    21241 tctactattt ccaaccaatt ccaagttttg aaacgtggag tctataccat tcgaaaagaa
    21301 ggggatgaat ataagattgc ctactataat cctgaaaccc aggaatcagc tccagatcag
    21361 gaagtcttta aaaagctaga gcaagcagct cagccacaag tacagaattc aaaagaaaag
    21421 gaaaaatctg aagaggaaaa gaaccattcg gatcaaaaga atctccctca gacaggagaa
    21481 ggtcagtcaa tcttggcaag tctagggttc ttgctacttg gggcgtttta tttattccgt
    21541 agaggaaaga acaactaatt tgttcatcat ctagatgaat tacatgaaac tgtggaaaat
    21601 agaaaaaatc cgaagaaggc caaatatctt cggatttttc ttttaaaaaa ggataagttg
    21661 atacttatcc tttttacttc attatgtgac tatagcgttt tgaaactaga ataggacatc
    21721 ataactgcta aaagatttct ataaattcat ttgattttcc taatcaattt attcgtatcc
    21781 tatttcactc tactatatta gtccgtctcg cacctcacgg agcgagacaa aacaaccacc
    21841 cgctatgcgg gtgcgcgtcg aaggttatac caaaaaaact ccaaacgcga tacaataaag
    21901 gtgttcaatc cacttgtaaa gcgaaaggag aaaaaatatg gcacaaaagg ctcatagttt
    21961 atctcacaca aagtggaggt gttctatcac attgtgttca cccctaagta tagacgaaaa
    22021 gtcatctata atcaatatag aagtagttta ggcgaaatat ttcatcgctt gtgtagttat
    22081 aaaggtgttg aaatgatcga gggtcactta atgccagacc atgtacacat gttagtcagt
    22141 attccactaa ggctaagtgt ttcgagtttc atgggttatt taaaaggaaa aagtgcactc
    22201 atgatgtttg acaaacacgc caatctcaag tacaagtttg ggaatcggca tttctgggtg
    22261 gaaggttatt atgtaagtac agtagagctt aataaagcca caattaagaa atatagtcaa
    22321 gattaaagaa attatccagt ggatgatttc ttcatgagta tgaaaatttg agaacgagta
    22381 aagcatgata tatagtaaaa tgaaataaga acagaacaaa tcgatcagga cagtcaaatc
    22441 gatttttaac aatgttttag aagtagaggt gtactattcc agtttcaatc tactatagca
    22501 ctagataaat tgagtgtaaa agaatatgag gatcccttta gggatagtgg taagtaatac
    22561 caaagtctct taaagaggca agtgacgagt caagagcaat aaggcttgaa caacgtgaaa
    22621 gccagcgtct ttaggcgctg gctggtaatt tgggcttata gctctgggat aaaccacccg
    22681 tttgacgggt ggttatgatt ttatctgagt gtaacatact gttgggcaat ctcgctgatg
    22741 cggtcaaagt tgccttggga agcgagttta ttgagttcgc caccaattcc aacggcgtct
    22801 gcaccagcag cgaaccattg agggatgttg tttagaccga ctcctccggt taccattacg
    22861 gaaacttgtg ggatcggtgc cttgattgca gagatatatg ctggactgag agcactacct
    22921 gggaagagtt tgatgatttc actaccggct tcaagtgcag tcgtgatctc tgtgagggta
    22981 atacagcctg gaatgtacgg tgtgctgtag agattgcaca ttttcgcagt ttcagcatgg
    23041 aaagatggag aaacaacgta atttgctccg gctagaatgg catctctagc agttacggca
    23101 tcaagcacag tacctgcacc gatacaaaca ctctgatcgt cctgatacaa gtctacaagt
    23161 tctttgatga tttgtcctgc atactgattg gtataggcga tttcaatagc tttgataccg
    23221 cccttgatac aagcaatcga ggcttgtagt ccttcttcct ttttatttcc tcgaatgaca
    23281 gcgacaattt tctgtttttt tagttcaata atcgtatctg atttggtcat gtaattctcc
    23341 taacgaatga tatcttgtgc atttgccagt aaattttcaa tactagttgc ggaagtggag
    23401 agatggtctc ctggaagagt gcatttgaga gttgcgctcg caactgcaaa gtcaatggta
    23461 gtttttaggg aggaatgatg gagtagttgg taaagggcac cagatataaa ggcatccccg
    23521 ctaccaattc gttgatagac tgcagttttt agttggacag actcttcaaa tagttcttct
    23581 agagcatagg cttgatagac atttttgtct tgctcatcac tagagcggag ggtatggaaa
    23641 atggccttga aaccataggc ttcttttaaa agtcgcatgc gattttccac ctcttctagg
    23701 ctagcactgt ctcttggaaa catctctaga ttttggtcat caatcatgag aggatcaata
    23761 ccgaagcaat agtcagtaaa acgtgcaaac ttagaaaatt catacttggc ttctaggact
    23821 gaaatcatct ttgttctcag attgagatcc attgaaacga caattcctcg gcgcttggct
    23881 tcttccaaga gtaggagaag gatcgcacgg acctcttgac cgatagctac ggtgattcca
    23941 ctaaaatgaa aatggctaat cccctgaaag agagaatcca tatctagcat gtttggccga
    24001 atctggctga tactcgtatg cttacgatcg tagaaaactt cactttgacg acaaccaaag
    24061 ccgttctcca aatagtagag gccgattcga tcgccaagcc gacagattga actggtatcg
    24121 atttggtgct gtttcaagaa tgtgagaaaa cgatctccaa tctcgttggc agggagtgcg
    24181 gtaaagactt tcgttgagat acccagagct tgcaaattac aagcgatgtt aatttctgat
    24241 ccgccaaaat aagtcgaact ggcaacatga tctccgatac tggtggcatc taatggtgag
    24301 attcgaatta atggttcgcc aaacagtaat attttcgtca tccattagtt cctttctggt
    24361 ttagaatagc tttacttggc taatacttct ttcaaataag cagcgacttc atcatcttgg
    24421 cagttttcaa agaagtattc ttggaagtat ttgccagata tggtgtcttt gaggaagtct
    24481 tggtcgattg ttttaaggat ggtcatcaaa tcattgtggg tgatttgttt cacctcgttt
    24541 aagatacgag cgttgcgttg ttcagggatt acacgttctc ttgggtagcc accgcccatt
    24601 tcttcagcaa ataagcgttc aaacatcaat ttgagggtca gttctgcccc ccagccaaat
    24661 cctttggcat aagggataga caaggcgtta ccaccattga tttgagaata aaggtaagcg
    24721 tcagttgggt ccactgctag accacagaca acaccaggga agctgtttaa agcaagcata
    24781 gcccctacac ccgtaccaca gccggtaaca acaaagtcaa ctgcctttgt atttaaaagg
    24841 atggcagcca ttagtccgtt ctgcacataa gttaattgac tttctccttc ttctccacgc
    24901 ataccatagt taaataattg gtagtctttt ttatctgtcg cttcttttag actatcgtaa
    24961 ataatgtgat tcttgctagc ttgactattt tcattgatta atgcgatttt cataagatct
    25021 tctttctatt tttactcagg ttgttttccg atgtaggcta agataccgcc atctacatat
    25081 aggatgtggc cattgacaaa attgctggca tcactagcga gaaagacagc agggcctatc
    25141 aaatcttcag gatttcccca acgtgcagca ggtgtttttg caatgatgaa ctggtcaaat
    25201 gggtggcgag aaccatcttc ttgcaactca cgaagaggtg ctgtttgagg agtggcaata
    25261 taacccggtc caattccgtt acattggata ttggctccac cgtattcaga cgcaatgttg
    25321 cgggtcaaca ttttcaagcc ccctttagca gcagcataag cgctaactgt ttcacgtccc
    25381 agttcgctca tcatcgaaca aatattgata atctttccat gccctttctt tatcatagaa
    25441 ggaataactg cctttgaaac gataaatggt gcgtttaagt caatatcgat gaccttacgg
    25501 aaatcagcgg cgctcatttc gcacattgga actcggcgga taataccagc gttattaacg
    25561 aggatgtcaa tgacaccaac ctcttgttcg atttgcttga ccatggcttg gataccgtcc
    25621 tcgtctgtca cgtcacagac atatccatgg gcttcgatgc caacttcacg ataagcttca
    25681 atccctttat tgaccagatc ttgattgata tcgttaaaga caatagtagc gccggcttca
    25741 gcgtaggatt tggcaatagc aaatccaatt ccataagaag cgccggtgat gagagcaatt
    25801 tttcctttta aagaaaactg ctcaattgag aatgatgtat ttgtcatttg atacttcctt
    25861 tcaaatttgt taagacttct ctataaccaa attatattct agtaaaccgg ttttgtcaat
    25921 aaataaatat ttttatttat aaaaagattt attttcctta aaaatggaat attttgaaat
    25981 ttctgtctat taaaatgatt aaaaagataa tgaaagcgct aatattttaa aaaaaaacta
    26041 ttgacaagat aaaaataaag gattacaatg gggaatataa agtaaaccgg taaacctaaa
    26101 caagaaagga gaaaagatga aaattgtact tgtagggcat ggacattttg ctacagggat
    26161 ttatagttct ttacaattga ttgcaggcaa tcaagaaaat gtggaggcaa ttgactttgt
    26221 ggaaggaatg tcagcagatg aactcaagca aaaaatctta cttgcaattt caaatgaaga
    26281 agaagtttta atcctaagtg atctcttggg aggatcgcca ttcaaggttt cttctaccat
    26341 aatgggagaa aatccagcca aaacaatgaa tgttctctcg ggtttgaact tagccatgtt
    26401 aatggaagca gtctttgcta gaatggctca tagctttgat gaggttgtta ataaatcagt
    26461 agtggcggcc cagggcggag tcgtaaatgg taaagaattg ttttcaacgg atgcagagga
    26521 agaggaagaa gatttcgaat cgggtattta aagggtaaaa gaatgataaa aaaggttacg
    26581 attgaaaaaa taaaatcgcc tgagcgcttc ttagaagtac cacttctgac gaaagaagaa
    26641 gtcggccagg caatcgataa ggttattcgg cagttagaac tcaaccttga ctatttcaag
    26701 gaagatttcc cgacgccagc tacctttgat aatgtctatc caatcatgga taacacggaa
    26761 tggaccaatg gtttctggac aggagaactg tggttggctt atgaatacag tcaacaggat
    26821 gcatttaaaa acatcgctca taaaaatgtt ctttcttttc tggatcgtgt caataagaga
    26881 gtagaattgg atcaccatga tctcggcttc ttgtacacac cgtcttgtat ggctgaatat
    26941 aagataaatg gagatggaga ggctagagaa gcaaccttga aagctgcaga taagttgatt
    27001 gaacgctatc aagaaaaagg tggttttatt caagcttggg gagacttggg caagaaagag
    27061 cattaccgtt tgattattga ctgcttgctc aatatccaac tcttattctt tgcttatcaa
    27121 gaaacaggcg atcaaaaata ctacgatatt gcagaaagcc atttctatgc ttcagctaat
    27181 aatgtaatcc gtgatgacgc ttcgtccttc cacaccttct attttgatcc tgagacaggt
    27241 caacccttta aaggtgtaac gagacaaggg tatagtgatg attcatgctg ggcacgtggt
    27301 caatcatggg gagtctatgg tattcctttg acttatcgtc acttaaaaga cgagtcctgc
    27361 tttgacttgt ttaagggtgt gaccaattat ttcttgaatc gtctgccaaa agatcatgtg
    27421 tcctattggg atttgatttt taatgatggt agtgatcaat cacgagattc ttcagcaaca
    27481 gctatcgccg tctgtgggat tcatgaaatg ctaaaacatc tcccagaggt ggatgctgac
    27541 aaagatattt ataaacatgc tatgcatgcc atgcttcgtt ccttgatcga acattatgca
    27601 aatgatcaat ttacccctgg tgggacaagt ctcctccacg gtgtgtactc atggcattca
    27661 ggtaaaggag tggatgaagg caatatctgg ggtgactact attacctaga agcccttatc
    27721 cgtttctaca aagactggaa cctatattgg taggaggaga aatatgacaa tgccaaatat
    27781 tattatgacc cgtatcgatg aacggttgat tcatggacaa ggacaacttt gggtaaaata
    27841 cctaggttgt aatacggtca ttgttgccaa tgacgaagta agcacggaca agatgcaaca
    27901 aactctgatg aaaacagttg tgccagactc agttgccatg cgtttcttcc ctttgcaaaa
    27961 ggtgattgat atcattcaca aggctaatcc tgctcaaacg atctttatcg ttgtaaagga
    28021 tgtgaaggac gctttaacct tggtagaagg tggtgtccct atcaaagaaa tcaatattgg
    28081 gaacattcac aatgctactg gtaaagagca agtgacacgc tccatcttcc tgggtgaaga
    28141 ggacaaggca gccctcaagg aattaagcca aactcatcaa gtaacattta atacgaaaac
    28201 aactccaaca ggaaatgatg gagctgttca agtcaacatt atggactata tttaaaagag
    28261 gagatcgtta tgtcgattaa tgtatttcaa gcgattttaa ttggattatg gacagctttc
    28321 tgttttagtg gaatgctatt aggaatttac accaatagat gtattgttct gtcatttggt
    28381 gtcggaatta ttctaggtga tctgcctact gctcttgcaa tgggagctat tggtgaattg
    28441 gcttatatgg gattcggtgt tggtgctgga ggtactgttc caccaaaccc aatcggacct
    28501 ggtatctttg gtaccttgat ggctatcact agtgctggta aagtcagtcc agaagcggct
    28561 cttgccctct ctactccgat tgctgtggcg attcaattct tacaaacttt cgcctacact
    28621 gtacgtgctg gtgcgcctga aacggcgatg aagcacttga aaaaccataa tttgaagaaa
    28681 ttcaagttca ctctaaatgc aacaatttgg ttgtttgcct ttattggatt taccttgggt
    28741 tgcttgggtg ccctttcaat ggataccttg ttgaaactcg tagactacat tccaccggta
    28801 ttgcttacag gtttgacagt tgctggtaaa atgctcccag ctatcggttt tgcgatgatc
    28861 ttgtcagtga tggctaagaa agagttgatt ccctttgtct tgttgggata tgtttgtgca
    28921 gcttatctaa acatcccaac aattggtatt gcaattgtag gtactatctt tgctttgatt
    28981 gaattttata acaagccaaa aacagcggat catgtggtag aggaggaagc acacgatgac
    29041 tggatctaac aaattaacaa aacgtgatta tcttaaaacg tctttgcggg cattcttttg
    29101 tcaaaatgga tttaactata gtaactatca agggttggga tatgccaatg tgatgtatcc
    29161 tgctttgaaa aaacactatg gagagaatca ggaaggtttc taccaagcct tggaagaaaa
    29221 ctgtgaattc tataatacca acccacactt cctgcctttt attaccagct tgcatcttgt
    29281 aatgttggaa aatggccgtc cggcaaaaga aacacgtagc atcaagatgg ccttgatggg
    29341 accattagca ggtattgggg attctctctc tcaattctgt ttagctccat tgttctcaac
    29401 catcgcagct tcgtttgctc aagaaggctt ggttgtcggt ccaatcttgt tcttccttgc
    29461 gatgaatacg attttaacag cgattaaatt gtcaactggt ctgtatggat acaaactagg
    29521 aacgactgtg attgataaac taagcgagca gatggcaacg atttctcgta ttgccaatat
    29581 tattggtgta accgtaattg ctggtttggc agcgacatct gttaagatta tggtaccgat
    29641 cacctttgct gcaggggaag ttaaagcaga cgctaaacaa agtatcgtaa gtattcaggg
    29701 aatgcttgat aaggttgctc cagctcttct accagcccta tttacacttt tagtttacta
    29761 cttgatcaaa gaaaagaaat ggacaacata taaactcgtt attttaacag ttatcatcgg
    29821 aattatcgga agctggctta agattatagc ttaatggata caacattgtt ttatggaata
    29881 gtgattgtct tggcagtgag tcccctttta ctgtcaagct ttcattctat tcgtcagcaa
    29941 aagttgcttc gcaaacagat ggagcaacga caagagtatt tagcttcttt aacatctggt
    30001 gatgaagtgt tgttattgtc tggaattcat ggaaaaatca tttctatcca agatgacttg
    30061 gtctccttgc agattgcaaa aggtgtggtc atctatgtag aaaaggaaag tgtaatggga
    30121 aagacaaaag aactgctttt taagtagttc tttttctggt aatagataat gaaagaagaa
    30181 agaagacaat tttttgaaag aatcgatgga aaccaatgtc gtgattatat cttgtcccac
    30241 tgttcaaaag actatgagaa agtcaagagt tcccttgaac gcttgatgga caatcgtttt
    30301 atgtttgata gtccttggga tatggagcct tgttcaaaaa tccatcaaat ccagccgatg
    30361 gtatgggatc aagtatttga agatgatcca gaatgggctt atatgctcaa tcgacaagaa
    30421 tatctcttgc agtttatgat agggtatgtg gtagaaggag ataaggacta tattcaaaag
    30481 tgcaagttct ttctatttga ttggattgag caggtgagag aattttctcc tcaatccttg
    30541 atgactagaa ccttggatac gggtattcgt tcctttactt ggttgaaact actcttgctc
    30601 ctcttgaaat ttgacttgct agaggagaaa gaactagaga aaattttggt cagtctagaa
    30661 aagcagattg actttatgaa aagccactat cgcgccaagt acacccttag taactggggg
    30721 attttacaaa caattccgat gcttgctatc tatcatttct tttcagataa gatggaccta
    30781 gaagaagctt accattttgc ttcagaggag ttgaaacagc aaattgagac acagatttta
    30841 ggagatggaa gccagtttga acagtcgatt ctctatcatg tagaggttta taaagccttg
    30901 ctggatttgt gtctcttgct tccagacttg caagatagtt accaagagtt gctggaaaag
    30961 atggcgacct atattcaaat gatgacaggc ttagatggac ggactttggc ttttggtgat
    31021 agcgattcta cagaaacgac agaaatgttg agcctgtctg ctgtggtttt gaacaaggaa
    31081 gatcttctta acggtctgga tgttaaagtc gatttgctta gcctcttgtt cctggggcga
    31141 gaaaaggtca agcgactgca ggaatttgaa aagagagctt ggcagcctaa gttcatgagc
    31201 tttgaagact ctggacatgt ctgcattaag gatgaacatc gttatctatt tttcaaaaat
    31261 ggtccgctag gaagtgccca tagccatagt gacgagaata gtttttgctt acagtatcaa
    31321 ggccaaccta ttttcataga tgctgggcgt tattcttatc gggagatata tgaacgttat
    31381 ctcttaaaga gtgcttggag tcattcgacc tgtattgtag atgggaaagc tccggaaaga
    31441 atcacgggat cctgggaata tgaatactat cctcactccc tgttttgtca ccataaagaa
    31501 agggagggaa tgcattatat tgaaggggct tattggtcag cagaacctga tttgccttat
    31561 cttcacagga gaaaaatcct catgctagta gaggatgtct ggctcttggt ggatgacatc
    31621 aggtgtcaag gtcagcatga ggcgttgact cagtttatcc ttgacaagga tgtgacctat
    31681 caagatggga aaatcaatca gttgagacta tggagtgaag ttgattttga tttggaagat
    31741 accatcattt ctcctaaata caatgagctt gaaagaagta gcaaactcac caagcgccaa
    31801 ttctttgaga atcagatgct ggattatacc atcattgcgc atgagagttt tgaaatcatc
    31861 cgtcattctg tctaccagac agatgatcgt gaagtggaaa atgctctggc ttttgaagtg
    31921 aaaaatgatg aaacagacaa gctgattctg ttattaagcg agaatattgg tgtaggtgaa
    31981 aaattgtgcc tcgttgacgg aacaaaaatg cgtggaaaat gtctagtata tgataaaata
    32041 aatgagagaa tgattcgctt gcagtgctag aaataggcat tttgaatagt gaatatgtta
    32101 taataagtat tagtaggagg tgttttagat tggagaagaa actgaccata aaagacattg
    32161 cggaaatggc tcagacctcg aaaacaaccg tgtcatttta cctaaacggg aaatatgaaa
    32221 aaatgtccca agagacacgt gaaaagattg aaaaagttat tcatgaaaca aattacaaac
    32281 cgagcattgt tgcgcgtagc ttaaactcca aacgaacaaa attaatcggt gttttgatcg
    32341 gtgatattac caacagtttc tcaaaccaaa ttgttaaggg aattgaggat atcgccagcc
    32401 agaatggcta ccaggtaatg ataggaaata gtaattacag ccaagagagt gaggaccggt
    32461 atattgaaag catgcttctc ttgggagtag acggctttat tattcagccg acctctaatt
    32521 tccgaaaata ttctcgtatc atcgatgaga aaaagaagaa aatggtcttt tttgatagtc
    32581 agctctatga acaccggact agctgggtta aaaccaataa ctatgatgcc gtttatgaca
    32641 tgacccagtc ctgtatcgaa aaaggttatg agcattttct cttgattaca gcggatacga
    32701 gtcgtttgag tactcggatt gagcgggcaa gtggttttgt ggatgcttta acagatgcta
    32761 atatgcgcca cgccagtcta accattgaag ataagcatac gaatttggaa caaattaagg
    32821 aatttttaca aaaagaaatc gatcccgatg aaaaaactct ggtatttatc cctaactgtt
    32881 gggccctacc tctagtcttt accgttatca aagagttgaa ttataacttg ccacaagttg
    32941 ggttgattgg ttttgacaat acggagtgga cttgcttttc ttctccaagt gtttcgacgc
    33001 tggttcagcc ctcctttgag gaaggacaac aggctacaaa gattttgatt gaccagattg
    33061 aaggtcgcaa tcaagaagaa aggcaacaag tcttggattg tagtgtgaat tggaaagagt
    33121 cgactttcta aaatgaagga aaatgacttg caatctctgt taagaaataa aataatccca
    33181 cctagaacaa gctaggtggg attatttgcc tataaaatga gaaattatgg gagcaagctc
    33241 ctaaatcaac tgtttttgat ctacttcttt aactacttga taaaagttat agaagtaggc
    33301 caaacttgaa atgatggtta cgactaggaa tattgaaaat ttccattgga cagggttggt
    33361 taaaagttgt ggaaaggata tgaggagaaa gaagagggct gcgttgagga caggtatccg
    33421 ttttgattgt attttctcaa gtcctttatt gagcgcagga agaaagagga gtaggagtag
    33481 taaaactgta tgagaaatag ctcctgaagt aagggcgaag aaaaggaaaa tactgataaa
    33541 aacatgaatg atcagtagtc tagctagtga tttcataagg cacctcctaa tcctggtctt
    33601 ttttagctct tgcaatacga agtgagtcga caatatgtat catcactccg aaaaagaaag
    33661 ctcccagtat agttttaaaa atatgttttg tatttagaag agaactgata aaatttggat
    33721 tttcacttgt tagggtatca atgagtggaa ttataaaaaa tatcactgtt ccataaatcg
    33781 aacctgcttt cagaccagga taacgtaact gtttcttttc ttttttcatg agtttcctcc
    33841 taatcctcat cttgattttt cttagttttt gcaatgcgac gggagatgag gaactgtatg
    33901 ctcgctccga agaaaataga accgagaata cttgatacac catttcttat agtgagaaga
    33961 gaatgaaaat agtcctgacc ttcatctatg agtatactga gaagaggagt tataaaaaac
    34021 atccatagac caaagaacaa acctgctttc agaccagggt agtgtagttg cttgctttct
    34081 ttctcattca gcatatctgg ttcaatgact gtgatgcctg tttttttcat ttggtaggtg
    34141 acatagccag aagcgatgag ggcaatcact aaaatcagag gaggatagat tagagccact
    34201 tcttgagggt atttataggc cagaaggagt ggaataatat ttccgaaaat catcagataa
    34261 aagaggacga taaagacttg gttcccaata ctatcggcct cacgccgttt gtattcgtca
    34321 aggggaccag aaataccgta tgtgcgtttg atcagttttt cagtgaaggt ttcttttttc
    34381 atgagtttgc ttctttttta aaaatcatcc tcccaaaaga gactgttgag gtcagtttgg
    34441 aggctgcggg cgagattgag acagagttcc aaggttggat tgtacttgtc gttttcaatc
    34501 atattgatag tctgtctcga gacaccgata tccttggcga gttcgagctg ggaaataccc
    34561 aattccttgc gaaattcttt cacacgattc atctggtctc ctttctgatt tatgtcgtat
    34621 atatttgact atattatagt cttttaaaca taaagtgtca agtatttttg acatattttt
    34681 tgaagaaata gtagtctcct tgtcctattt gtctgacaag tgcaagctgg tcggatttgt
    34741 ggtaaaatag ataagatatg acaaaagaat ttcatcatgt aacggtctta ctccacgaaa
    34801 cgattgatat gcttgacgta aagcctgacg gtatctacgt tgatgcgact ttgggcggag
    34861 caggccatag cgagtattta ttaagtaaat taagtgaaaa aggccatctc tatgcctttg
    34921 accaggatca gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac attgagaagg
    34981 gaatggtgac ctttatcaag gataacttcc gtcatttaca ggcacgtttg cgtgaagctg
    35041 gtgttcagga aattgatgga atttgttatg acttgggagt gtctagtcct caattggacc
    35101 agcgtgagcg tggtttttct tataaaaagg atgcgccact ggacatgcgg atgaatcagg
    35161 atgctagtct gacagcctat gaagtggtta atcattatga ctatcatgat ttggttcgta
    35221 ttttcttcaa atacggtgag gataaattct ctaaacagat tgcgcgtaag attgagcaag
    35281 cgcgtgaagt gaagccgatt gagacaacga ctgagttagc agagattatc aagttggtca
    35341 aacctgccaa ggaactcaag aagaaggggc atcctgctaa gcagattttc caggctattc
    35401 gaattgaagt caatgatgaa ctgggagcgg cagatgagtc catccagcag gctatggata
    35461 tgttggctct ggatggtaga atttcagtga ttacctttca ttccttagaa gaccgcttga
    35521 ccaagcaatt gttcaaggaa gcttcaacag ttgaagttcc aaaaggcttg cctttcatcc
    35581 cagatgatct caagcccaag atggaattgg tgtcccgtaa gccaatcttg ccaagtgcgg
    35641 aagagttaga agccaataac cgctcgcact cagccaagtt gcgcgtggcc agaaaaattc
    35701 acaagtaaga gggaaaaaga tggcagaaaa aatggaaaaa acaggtcaaa tactacagat
    35761 gcaacttaaa cggttttcgc gtgtggaaaa agctttttac ttttccattg ctgtaaccac
    35821 tcttattgta gccattagta ttatttttat gcagaccaag ctcttgcaag tgcagaatga
    35881 tttgacaaaa atcaatgcgc agatagagga aaagaaaacc gaattggacg atgccaagca
    35941 agaggtcaat gaactattac gtgcagaacg tttgaaagaa attgccaatt cacacgattt
    36001 gcaattaaac aatgaaaata ttagaatagc ggagtaagat atgaagtgga caaaaagagt
    36061 aatccgttat gcgaccaaaa atcggaaatc gccggctgaa aacagacgca gagttggaaa
    36121 aagtctgagt ttattatctg tctttgtttt tgccattttt ttagtcaatt ttgcggtcat
    36181 tattgggaca ggcactcgct ttggaacaga tttagcgaag gaagctaaga aggttcatca
    36241 aaccacccgt acagttcctg ccaaacgtgg gactatttat gaccgaaatg gagtcccgat
    36301 tgctgaggat gcaacctcct ataatgtcta tgcggtcatt gatgagaact ataagtcagc
    36361 aacgggtaag attctttacg tagaaaaaac acaatttaac aaggttgcag aggtctttca
    36421 taagtatctg gacatggaag aatcctatgt aagagagcaa ctctcgcaac ctaatctcaa
    36481 gcaagtttcc tttggagcaa agggaaatgg gattacctat gccaatatga tgtctatcaa
    36541 aaaagaattg gaagctgcag aggtcaaggg gattgatttt acaaccagtc ccaatcgtag
    36601 ttacccaaat ggacaatttg cttctagttt tatcggtcta gctcagctcc atgaaaatga
    36661 agatggaagc aagagcttgc tgggaacctc tggaatggag agttccttga acagtattct
    36721 tgcagggaca gacggcatta ttacctatga aaaggatcgt ctgggtaata ttgtacccgg
    36781 aacagaacaa gtttcccaac gaacgatgga cggtaaggat gtttatacaa ccatttccag
    36841 ccccctccag tcctttatgg aaacccagat ggatgctttt caagagaagg taaaaggaaa
    36901 gtacatgaca gcgactttgg tcagtgctaa aacaggggaa attctggcaa caacgcaacg
    36961 accgaccttt gatgcagata caaaagaagg cattacagag gactttgttt ggcgtgatat
    37021 cctttaccaa agtaactatg agccaggttc cactatgaaa gtgatgatgt tggctgctgc
    37081 tattgataat aatacctttc caggaggaga agtctttaat agtagtgagt taaaaattgc
    37141 agatgccacg attcgagatt gggacgttaa tgaaggattg actggtggca gaatgatgac
    37201 tttttctcaa ggttttgcac actcaagtaa cgttgggatg accctccttg agcaaaagat
    37261 gggagatgct acctggcttg attatcttaa tcgttttaaa tttggagttc cgacccgttt
    37321 cggtttgacg gatgagtatg ctggtcagct tcctgcggat aatattgtca acattgcgca
    37381 aagctcattt ggacaaggga tttcagtgac ccagacacaa atgattcgtg cctttacagc
    37441 tattgctaat gacggtgtca tgctggagcc taaatttatt agtgccattt atgatccaaa
    37501 tgatcaaact gctcggaaat ctcaaaaaga aattgtggga aatcctgttt ctaaagatgc
    37561 agctagtcta actcggacta acatggtttt ggtagggacg gatccggttt atggaaccat
    37621 gtataaccac agcacaggca agccaactgt aactgttcct gggcaaaatg tagccctcaa
    37681 gtctggtacg gctcagattg ctgacgagaa aaatggtggt tatctagtcg gggtaaccga
    37741 ctatattttc tcggctgtat cgatgagtcc ggctgaaaat cctgatttta tcttgtatgt
    37801 gacggtccaa caacctgaac attattcagg tattcagttg ggagaatttg ccaatcctat
    37861 cttggagcgg gcttcagcta tgaaagactc tctcaatctt caaacaacag ctaaagcttt
    37921 ggagcaagta agtcaacaaa gtccttatcc tatgcctagt gtcaaggata tttcacctgg
    37981 tgatttagca gaagaattgc gtcgaaatct tgtacaaccc atcgttgtgg gaacaggaac
    38041 gaagattaaa aacagttctg ctgaagaagg gaagaatctt gccccgaatc agcaagtcct
    38101 tatcttatct gataaagcag aggaggttcc agatatgtat ggttggacaa aggagactgc
    38161 tgagaccctt gctaagtggc tcaatataga acttgaattt caaggctcgg gctctactgt
    38221 gcagaagcaa gatgttcgtg ctaacacagc tatcaaggac attaaaaaaa ttacattaac
    38281 tttaggagac taatatgttt atttccatca gtgctggaat tgtgacattt ttactaactt
    38341 tagtagaaat tccggccttt atccaatttt atagaaaggc gcaaattaca ggccagcaga
    38401 tgcatgagga tgtcaaacag catcaggcaa aagctgggac tcctacaatg ggaggtttgg
    38461 ttttcttgat tacttctgtt ttggttgctt tctttttcgc cctatttagt agccaattca
    38521 gcaataatgt gggaatgatt ttgttcatct tggtcttgta tggcttggtc ggatttttag
    38581 atgactttct caaggtcttt cgtaaaatca atgaggggct taatcctaag caaaaattag
    38641 ctcttcagct tctaggtgga gttatcttct atcttttcta tgagcgcggt ggcgatatcc
    38701 tgtctgtctt tggttatcca gttcatttgg gatttttcta tattttcttc gctcttttct
    38761 ggctagtcgg tttttcaaac gcagtaaact tgacagacgg tgttgacggt ttagctagta
    38821 tttccgttgt gattagtttg tctgcctatg gagttattgc ctatgtgcaa ggtcagatgg
    38881 atattcttct agtgattctt gccatgattg gtggtttgct cggtttcttc atatttaacc
    38941 ataagcctgc caaggtcttt atgggtgatg tgggaagttt ggccctaggt gggatgctgg
    39001 cagctatctc tatggctctc caccaagaat ggactctctt gattatcgga attgtgtatg
    39061 tttttgaaac aacttctgtt atgatgcaag tcagttattt caaactgaca ggtggtaaac
    39121 gtattttccg tatgacgcct gtacatcacc attttgagct tgggggattg tctggtaaag
    39181 gaaatccttg gagcgagtgg aaggttgact tcttcttttg gggagtggga cttctagcaa
    39241 gtctcctgac cctcgcaatt ttatatttga tgtaagaatg gcaccctgat gtttcagggt
    39301 gtttttgtgt ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct aactttaggc
    39361 tgctcaaaac atagtagttt gaaactagaa tagtacacat ctacttctaa aatattgtta
    39421 gaaatcgatt tgactgtcct gatcgacttg tcctgttctt atttcatttt actatacagt
    39481 tttgagatgg ttgatagaac tgacgaagtc agctcaaaac acggttttga ggttgtagat
    39541 aaggagaagc tgatgtggtt tgaagaggtt ttcgaagagt gtaaaaaaat attggtcagt
    39601 taaagtcaaa actattgacc ttttctgacc aatgtagtat attatgaacg taaggtaaat
    39661 gaaagcctta ctagaacact tatttaaagt aaaatagaaa gaggtgggtc tatgtttcat
    39721 ctagaaatct tcagaagtaa agatggtcta ctcctgcttg aaaaagaaaa accagaaata
    39781 gtacgtaggg tagcggttta gctagtctaa attttttaaa acaaaggtca aagatagtca
    39841 atatcagtaa tcataactaa gtaaacaaaa agaggtaaag aatatgaata acaactttaa
    39901 taattttaat aacatggatg atttatttaa ccaattgatg ggtggtatgc gaggatatag
    39961 ttctgaaaat cgccgttact taattaatgg acgcgaagtc acacctgagg aatttgctca
    40021 ctatcgtgcg actggtcaat taccaggaaa tgcagaaact gatgtgcaaa tgccacaaca
    40081 ggcatcaggt atgaaacaag acggtgtcct tgcaaaacta ggtcgaaact taacagcaga
    40141 agcgcgtgag ggcaagttgg atcctgttat cggacgaaac aaggaaattc aagaaacatc
    40201 tgaaatcctc tcacgccgca ccaagaacaa tcctgttttg gtcggagatg caggtgttgg
    40261 taagacagca gttgtcgaag gtctagcgca agccattgtg aacggagatg ttcctgctgc
    40321 tatcaagaac aaggaaatta tttctattga tatctcaggt cttgaggctg gtactcaata
    40381 ccgtggtagc tttgaagaaa atgtccaaaa cttagtcaat gaagtgaaag aagcagggaa
    40441 tattatcctc ttctttgatg aaattcacca aattcttggt gctggtagca ctggtggaga
    40501 cagtggttct aaagggcttg cggatattct caagccagct ctctctcgtg gagaattgac
    40561 agtgattggg gcaacaactc aagacgaata ccgtaacacc atcttgaaga atgctgctct
    40621 tgctcgtcgt ttcaacgaag tgaaggtcaa tgctccttca gcagagaata cttttaaaat
    40681 tcttcaaggc attcgtgacc tctatcaaca acaccacaat gtcatcttgc cagacgaagt
    40741 cttgaaagca gcggtggatt attctgttca atacattcct caacgtagat tgccagataa
    40801 ggctattgac cttgtcgatg taacggctgc tcacttggcg gctcaacatc cagtaacaga
    40861 tgtgcatgct gttgaacgag aaatcgaaac ggaaaaagac aagcaagaaa aagcagttga
    40921 agcagaagat tttgaagcag ctctaaacta taaaacacgc attgcagaat tggaaaggaa
    40981 aatcgaaaac cacacagaag atatgaaagt gactgcaagt gtcaatgatg tggctgaatc
    41041 cgtggaacga atgataggta tcccagtatc gcaaatggga gcttcagata tcgaacgttt
    41101 gaaagatatg gctcatcgct tgcaagacaa ggtgattggt caagataagg ccgtagaagc
    41161 tgtagctcgt gctatccgtc gtaaccgtgc tggttttgat gaaggaaatc gcccaatcgg
    41221 cagcttcctc tttgtagggt ctactggggt tggtaagacg gagcttgcta agcaattggc
    41281 actcgatatg tttggaaccc aggatgcgat tatccgtttg gatatgtctg aatacagtga
    41341 ccgcacagct gtttctaagc taattggtac aacagcaggc tatgtgggtt atgatgacaa
    41401 tagcaatacc ttaacagaac gtgttcgtcg caatccatac tctatcattc tcttggatga
    41461 aattgaaaag gctgaccctc aagttattac ccttctcctc caagttctag atgatggtcg
    41521 tttgacagat ggtcaaggaa atacagtaaa cttcaagaac actgtcatta ttgcgacctc
    41581 aaatgctgga tttggctatg aagccaactt gacagaagat gcggataaac cagaattgat
    41641 ggaccgtttg aaacccttct tccgtccaga attcctcaac cgctttaatg cagtcatcga
    41701 attctcacac ttgactaagg aagacctttc taagattgta gatttgatgt tggctgaagt
    41761 taaccaaacc ttggctaaga aagacattga cttggtagtc agtcaagcgg ctaaagatta
    41821 tatcacagaa gaaggttacg acgaagtcat gggagttcgt cctctccgtc gagtggttga
    41881 acaagaaatt cgtgataagg tgacagactt ccacttggat catttagatg ctaaacatct
    41941 ggaagcagat atggaagatg gcgttttggt tattcgtgag aaagcctaag atagaatttt
    42001 gaggataaaa aagaaggagc cagctgaaaa aaaactggtt ccttttgagg tacgacgggc
    42061 atgtcgtata gtagaagtgt attattctag tttcaattta ctatagtagc tcagaagtcg
    42121 gtacttaaac gtgctatatc aaaaccagtc cttgaaaaac gtggactggt ttcgtgtttg
    42181 gattattacc ttgaacgaca tgcgttaaaa gttagttgaa ccgccgtatg ccgaacggca
    42241 cgtacggtgg tgtgagaggg gctagagatt atcccctact cgattttaaa tcacatgacg
    42301 ttcaaaggca tcatctgaaa tcccttgttc caagatgagt tttgcccatt ctttagcaga
    42361 gaagaggctg tggtccttgt agtttccgca agattcgatg gttgtccctg ggacatcttc
    42421 ccaagtagta gtttcagcga tttccttgag cgaatccttg ataacagctg cgattttagc
    42481 actggtgtga cgtccccaca taatcatgtg gaagcctgtg cggcaaccaa atggtgaaca
    42541 gtcaatcatg ccgtcaatgc gggtacggat gagtttggct aagaggtgct cgatagtgtg
    42601 aaggccggcg gtagggatag agtcttcgtt tggttgcacc aagcgaatat cataattgga
    42661 gatgatgtct ccttttggtc ctgtttcttc cccaatcaag cgaacatagg gtgctttgac
    42721 aatggtgtgg tcaagttcaa aactttcgac aataacttct tttgacatgg taaatccttt
    42781 cagttttctt ctctcattat atcataaagg ttgctcctga gacagagaga aaacctctcc
    42841 gaggctggag aggttgaaat ctttacttac gatataagcg gtcgtattgg tagtatgggt
    42901 caaaggttac gttgatatcc agtttacgaa ggacattctt gtcttcatca gtcaagatga
    42961 tggttgagtg ggcttcgctt cctttgaggt tgccgagttc ttccatagcg cgggcagcat
    43021 caggattttc tgtagctgtg atagcaagtg caatcaggat ttcatttgaa tgaaggcgtg
    43081 gattgcggct accgagatga tcgattttaa gaccttggat tggcttaaca acttcaggtt
    43141 cgattagttt tacttcttta gcgatgtcag ctgatttttt gatggcgttg atcaaggcag
    43201 cggctgtagg accaaagagt tctgagttct taccagtgac gatttcccca tttggcaatt
    43261 caaaggctag ggctggtcca ccagtttctt ctgctttttg gcgcgcaacg acagcaacct
    43321 tacggtctgc aggtgtgata ccgaggtcgt tcatgagcaa ctcaattttc ttgacggcag
    43381 cttcgccaac tttttcagct ttgaagtcaa gaattgtttg atagtaacgg cggatgattt
    43441 cttgtttaga agcttcgaca gcggcctcgt catctgtaat agcgaaacca accatgttga
    43501 cacccatatc tgtcggtgaa gcgtatggtg attttccgag aatacgttcc aacatgcgtt
    43561 tgagcactgg gaagatttcg atatcacggt tgtagttgac agtggtttct ccataggttt
    43621 gaagatggaa ggggtcaatc atgttgacat catcaaggtc agctgtggca gcttcataag
    43681 ccaagttaac tggatgatga aggggaagat tccaaacagg gaaggtttca aatttagcgt
    43741 agccagactt gatgccattg atttggtcgt ggtacatatt ggacatacac gttgccaatt
    43801 ttccagaacc gggtccagga gcggttacga caatcaagtt gcgactggtt ttgatgtagt
    43861 cgtttttgcc catgccttct ggggaaatga tgtgatccat atccgtcgga tatcctttga
    43921 ttggataatg aagataagaa tcaattctgt ttttctcaag ttggttgcgg aaggcatctg
    43981 cagcgagttg gccagcgtat tgtgtaatga caacggaacc aacaaaaatc cctaattcat
    44041 tgaatttgtc aatcaaacga agaacttctt ggtcataaga aatgcctaag tcgccacgtg
    44101 ctttggaatg ttcaatgttg ctagcattaa tggcaatcac aacctcaact tgctctttca
    44161 attcttgcaa gagcttgatt ttgttgtcag gttcataacc aggaaggaca cgagcagcgt
    44221 ggaaatcttc taacattttg ccaccaaact ctaggtaaag cttgccgtca aattggttaa
    44281 tgcgatctaa gatgtggtcg cgttgtagat ttaaatattg ttcagaacta aaagcttgtt
    44341 ttttcatttt tttacctctg gactctatta taataaaaaa ttggaagtta ggaaactacg
    44401 gagctaaaaa agaaattaaa aagattaagc aaacgcttgc acaaaatttt aaaaagtgct
    44461 attatagact atagattatg aaaataatga ggtaagaaga tgcaagaaaa atggtggcat
    44521 aatgccgtag tctatcaagt ctatccaaag agttttatgg atagtaatga agatggaatt
    44581 ggcgatttgc caggaattac cagtaagttg gactatctag ccaagctagg aatcacagca
    44641 atttggcttt ctcccgttta tgacagccct atggatgata atggctacga tattgctgat
    44701 tatcaagcga ttgcggctat ttttggaacc atggaggaca tggatcagct gattgcagaa
    44761 gctaagaagc gtgatatccg tatcatcatg gacttggtgg tcaatcatac ctcggatgag
    44821 catgcttggt ttgtcgaagc ctgtgaaaat actgacagcc ctgagcgaga ctactatatc
    44881 tggcgcgatg aacccaatga cctagattct atctttagtg ggtctgcttg ggaatacgat
    44941 gaaaagtcag gtcaatacta tctccacttt ttcagcaaga aacagccgga tctcaactgg
    45001 gaaaatgaaa aacttcgcca gaaaatttat gagatgatga acttctggat tgataaaggt
    45061 attggtggtt tccgtatgga tgttattgac atgattggca aaattcctga cgagaaggta
    45121 gtcaataatg gtcctatgct ccatccctat ctcaaggaaa tgaatcaggc gacctttgga
    45181 gataaggagc tcttgacagt aggggagact tggggagcaa cgccagagat tgccaagctc
    45241 tactctgatc caaaggggca agaattgtct atggtcttcc agtttgaaca tatcggtctt
    45301 cagtatcagg aaggtcagcc taaatggcac tatcaaaaag agctgaatat tgctaagtta
    45361 aaagaaatct tcaacaaatg gcagacagag ttaggagttg aggacggctg gaattccctc
    45421 ttctggaaca accatgacct ccctcgtatt gtctcaatct ggggaaatga ccaagaatac
    45481 cgtgaaaaat ctgccaaagc ctttgcgatt ttgcttcatc tcatgagagg gactccttat
    45541 atctaccaag gtgaggagat tgggatgacc aactatccgt ttgaaacact ggatcaagta
    45601 gaagatattg aatctctcaa ctatgcgcgt gaggctcttg aaaaaggtgt tccgattgaa
    45661 gaaatcatgg acagtatccg tgttattgga cgtgacaatg cccgtacccc tatgcaatgg
    45721 gacgagagca aaaacgctgg tttctcaaca ggtcaacctt ggttggcggt taatccaaac
    45781 tacgaagaaa tcaacgttca agaagcactg gcaaactcag attctatttt ctatacctat
    45841 cagaaactca tccagattcg taaggaaaac agctggttga ttcgagctga ttttaaatta
    45901 ctcgatacgg ctgataaggt ctttgcttat atccgtaagg acggtgaccg tcgcttccta
    45961 gtcgtggcta atttatccaa tgataaacaa aacttttcag tagatggaaa agttagatct
    46021 gtcttgattg aaaacactgc ggctaaagaa gtacttgaaa aacaggtctt gactccatgg
    46081 gatgctttct gtgtggaaat gactgactag aatgagcaag agcctgggac aaaatagttc
    46141 tcgaccacaa aaaagctaga gatttccaat tgtggaactc tagcttttta attttgagtc
    46201 attctcttat tgtattttag gaggttattg gccataagta ccaatcccat gtcaattctc
    46261 acttgacgct tgcccctcag attacatctc ttgtaaccca aacaagcctt tatctgccca
    46321 aagacaggtt ccacatcaat cttgcgttga gcgaaaatct gtctaccttg gggagataaa
    46381 agcgcctgac attctttagc tttcaagttt tgatagcctt cgttcatata cagtcccctt
    46441 ttgaggggct gattcaggtt cgtcgacgta gtaaaccttg atttcttgtt gaaagtctgt
    46501 ctgtgttttc tgatgtttgg tatggtgaaa acgataatac tagccatcag gatgtgtata
    46561 gctatcctcc ttgtcattat agtgccaatt cgctaagttt ttagctgact gtttatagcc
    46621 tctcttctgt tccttatcaa acatggcata tttaatcaga tggtttacct ccttttcatc
    46681 taaacgaagg aggttctctt cacttccata tccagcatct gcgacaactg tcttcaagtc
    46741 atgcggatag gtttcaagga atggcagaag agtcttggta tctgtcggat ttgaaaagac
    46801 atcatagtga agaacaaatt ggttttccgt agcgatttga agattataag cagccttggg
    46861 ttgactattt ttcatatgtt cttccttcat ccgcataaaa gtggcatctg gatcggtttt
    46921 ggaaaaactg ttaggccctt gaaatgtctc ctgatagttc tcatattttt cagcacgtac
    46981 tgaaaaatcc tcctttaaac tcttcataat cctttttatt tttatgaaga tattgtttga
    47041 aagatgtgag tttccacgga tgggtttgtg gagggatata cttgcgtctt tctttttttg
    47101 ttctggttct tgttcaaggt ttttcgaata gagttcatga tttagtagct cctttgtgtg
    47161 atagattttg tcagcgatat tgaggtagat gtcaccatca aatgctttta taactaatgc
    47221 ttttgtcttt ctgatgaaat agacttcttt tccttgctcg gtagggatat agcaacgatt
    47281 ttggaatcgg atatggtgtc cactatcgac gactctctcc cgccagttta gctagaatga
    47341 gatttcgttc agagggctta ggagcctcct caaagacaga gagttttgtc ttgtttccaa
    47401 actgttcatt aaaggtttgg atataggaag gcagaaaggt attggcttct tccaaggtat
    47461 gaatcttgtt tcgttccagt tcgataggca agagagattg tagtatctga ttgagtcttt
    47521 cgactctccc tttagcttga gggatagagg ttgtctcaag gagaattccc agttggtgac
    47581 aggcgtatcc aaattgtgta tgggtgtcgt cctccatttt cttagagttg gaggcttgat
    47641 aggtaaaaac agttctctta tctgttttga tttgaacagg aatgccgtgg ttggctaaga
    47701 tttgttcgag gacatgatag taagcattca aggtctcttg tttgtcaaaa taagcgccta
    47761 ggatattgcc agaagcatca tcaatggcta ggtgtaagtt agaggtttct gctccaaacc
    47821 aggcatgagg gctggcatcc atttggatga gttctccagc aaatttcttt ctgggtctac
    47881 taggatgtac ctttttaggg tcttccagga agttttcagc cgtcggtaag attggattgt
    47941 ctaggggttg cttggggttc agtttagctt gctttcttac tctcttcttt gtctttctat
    48001 gggacttagg cgacaggata tttttcttat agagtatttt tctaacagta gtatcagaga
    48061 gctgaattcc ttcttcttca gctagcaatt cacagaaatg acggacattt ggtttatatg
    48121 tttcatagga gaggtatttc tttaggatac gttctttgat ttcatcaggg attgcatgtt
    48181 ttggttttcg atttctgttt ccgtgtctga aggcttcttt tcctttctgt tgataggcta
    48241 gtagcagacg attgatttgc ctttcagaaa gattgagctc gacacaggct cgtttctttg
    48301 ttttctttcc ttgggctata gcttttatca caagatattt tttcgtttca ttcatattca
    48361 gttggatcct ttacatatga ctattctacc aaatgggaca tttttacgtt cgatttacta
    48421 aagacattat cacattcgaa ttacacaaga tgcagatagt gaaaaaaagg tgtagacatt
    48481 accgtaaaaa agtgatacaa ttgtaagatg ttcaatgtat aggtgttaat catgagtaga
    48541 cgttttaaaa aatcaggttc acagaaagtg aagcgaagtg ttaatatagt tttgttgact
    48601 atttatttat tgttagtttg ttttttattg ttcttaatct ttaagtacaa tatccttgct
    48661 tttagatatt ttaatctagt ggtaactgcg ttagtcctac tagttgcctt ggtagggcta
    48721 ctcttgatta tctataaaaa agctgaaaag tttactattt ttctgttggt gttctctatc
    48781 cttgtcagct ctgtgtcgct ctttgcagta cagcagtttg ttggactgac caatcgttta
    48841 aatgcgactt ctaattactc agaatattca atcagtgtcg ctgttttagc agatagtgat
    48901 atcgaaaatg ttacgcaact gacgagtgtg acagcaccga ctgggactga taatgaaaat
    48961 attcaaaaac tactagctga tatcaaatca agtcagaata tcgatttgac ggtcaatcaa
    49021 agttcgtctt acttggcagc ttacaagagt ttgattgcag gagagactaa ggccattgtc
    49081 ttaaatagtg tctttgaaaa tatcatcgaa tcggagtatc cagattacgc atcgaagata
    49141 aaaaagattt ataccaaggg attcactaaa aaagtagaag ctcctaagac gtctaagaat
    49201 cagtctttca atatctatgt tagtggaatt gatacttatg gtccgattag ttcggtgtcg
    49261 cgttcagatg tcaatatcct gatgactgtc aatcgagata ccaagaaaat tctcttgacc
    49321 acaacgccac gtgatgctta tgtaccaatc gcagatggtg ggaataatca aaaagataaa
    49381 ttgacccatg cgggcatcta tggagttgat tcgtccattc acaccttaga aaatctctat
    49441 ggagtggata tccattacta tgtccgtttg aacttcactt ctttcttgaa attgatcgat
    49501 ttgttgggtg gggtagatgt ttataatgac caagatttca catctctaca cgggaagttc
    49561 catttcccag ttggaaatgt ccacttagat tctgagcagg ctctgggatt tgttcgtgag
    49621 cgctattccc tagcggatgg tgatcatgac cgcgggcgca atcaacaaaa ggtgattgcg
    49681 gctatccttc aaaaattaac ttcgagcgaa gcgctgaaaa attatagtat gatcattgat
    49741 agcttgcaag attctatcca aacaaacatg ccccttgaga ccatgataaa cttggtcaat
    49801 gctcagttag aaagtggtgg aacgtacaaa gtaaattcgc aagacttgaa gggtagggga
    49861 cggacggatc ttccttccta tgcgatgcca gatagtaacc tctatatgat ggaaattaac
    49921 gacagtagcc ttgcatctgt caaaactgct attcaggatg tgttggaggg cagatgaaat
    49981 gattgatatt cattcgcaca ttgtctttga tgtagatgat ggtcccaagt caagagagga
    50041 aagtaaggct ctcttgacag aagcctacag gcagggggtg cgaaccattg tctctacctc
    50101 tcaccgtcgc aagggcatgt ttgaaactcc agaagagaag atagcagaaa actttcttca
    50161 ggttcgggaa atagctaagg aagtcgcgag tgacttggtc attgcttatg gggccgaaat
    50221 ttactacaca ccagatgttt tgggtaagct ggaaaaaaat cggattccga ccctcaataa
    50281 tagtcgttat gccttgatag agtttagtat gaacacccct tatcgcgata ttcatagtgc
    50341 cttgattaaa atattgatgt tgggaattac tccagtcatt gcccacatcg agcgctatga
    50401 tgctcttgaa aataatgaaa aacgcgttcg agagctgatt aatatgggct gttacacgca
    50461 agtaaatagt tcacatgtcc tcaaatccaa actttttgga gaaccttata aattcatgaa
    50521 aaaaagagct cagtatttct tggagcgtga tttggttcat gtgattgcaa gtgatatgca
    50581 taatgtggac agcagacctc cccatatggc agaagcatat gaccttgttt cccaaaaata
    50641 cggagaaacg aaggctcagg acctttttat agacaatcct cgaaaaattg taatggatca
    50701 actaatttag gagaaataat gaaagaacaa aacacgatag aaatcgatgt atttcaatta
    50761 cttaaaacct tgtggaaaca caagctaatc attttattag tggcacttgt gacaggggcg
    50821 ggagcttttg catatagcat ttttattgtt aagccagaat atacaagcac cacgcgtatt
    50881 tacgtagtca atcgtaatca agaaaataag ccgggactga cgaatcagga cttgcaggca
    50941 ggaacttatc tggtaaaaga ctaccacgaa attatccttt cgcaagatgt attggaaaag
    51001 gtagcgacaa atttgaaatt ggatattcca gtaaaaacgt taactagcaa agtgcaagtg
    51061 actgtaccag ccgacactcg tatcgtctca atctctgtca aggataaaca accagaggaa
    51121 gccagtcgca ttgctaattc tatacgagaa gttgctgcag aaaagatcat cgctgtaacg
    51181 cgagtatctg atgtaacgac gcttgaagaa gcgcgaccag ctacgactcc ctcttctcca
    51241 aatgttcgac gcaacacctt agttggtttt cttggagccg ccgccgtaac agtaattact
    51301 gttcttttga ttgagttgtt cgatacccgt gtaaaacgtc ctgaagaagt tgaagatgta
    51361 ctgcaaatgc cacttctagg agtcgttcca gattttaata aaatgaaata ggaggaagtt
    51421 atgccaacgt tagaaatctc acaggcgaaa ttagaacttg cgaaaaagac agaggaatat
    51481 tataatgctt tgtgcacgaa cctacagtta agtggagatg atttgaaagt attttctatc
    51541 agttctgtga aagcaggaga aggaaaaaca acgacttcca ccaatatcgc ttgggctttt
    51601 gcgcatgcag gttacaaaac gctgctgatt gatgcagaca tgcgtaactc cgttatgtca
    51661 ggtgtcttta aatcaaggga aaggattact gggctaacag aatttctatc agggacaaca
    51721 gacctgtcac aggggctttg cgataccaat gttgagaatc tctttgtgat tcaggctggc
    51781 tctgtgtcac caaatccgat agcccttctt caaagtaaga atttcagtac aatgcttgga
    51841 accttgcgta aatattttga ctatatcgtc gtagacactg ctcctatcgg tatcgtgatt
    51901 gatgcggcta tcattatgca gaaatgtgat gcttctattt tagtgacgaa ggcaggtgaa
    51961 acaaaacgac gggaacttca aaaagcgaaa gaacagttgg aacaaactgg gaagtcgtgt
    52021 ttaggagttg tgttgaataa attcgatact tcagtagaca aatacggttt ttatgggagt
    52081 tatgggagtt atgggagtta caggaaacag aaaaaatagg ttgagggata gagatgaatg
    52141 aaaaactagc aaagtcttca gtagctatag tccagagttt tcttgttatt ttattgactt
    52201 atctacttag cgctgtgaga gaaacagaga ttgtttcaac aacagctatt gtactttata
    52261 tcctccacta ttttgtcttt tatatcagtg attatggacg gaatttcttt aaaaggagat
    52321 atttgattga acttgtccag acattgaaat atatcctatt ctttgcgcta gcgattagta
    52381 tttctaattt tttcttagag gatcgattta gtatttccag acgaggcatg atttacttcc
    52441 tcctattaca tgttttctta gtctatatgc taaacctatt tatcaagtgg tattggaagc
    52501 gggcttatcc caactttaaa ggaagtaaga aggttttcct acttacagca acttctcatg
    52561 tcgaaaaggt actggataga ctaatagaat cagatgatgt tgttggggag ttggtagccg
    52621 tcagtgtttt agataaacca gattttcagc atgatgattt aaaggttgta gcagaggggg
    52681 agatcgtaaa ctttgcgact cgtgaggtgg tcgatgaagt ctttatcaat cttccaagtg
    52741 aaaaatacaa tattggagag cttgtctctc agtttgaaac gatgggaatt gatgtaacag
    52801 tcaatctaaa tgctttcgat tgggcacgta acaagcaaat ttgtgagatg gcaggactaa
    52861 atgttgtgac tttttctaca acattttata agactagcca tgtgattgct aagcgggtta
    52921 ttgatattat cggttccctg gtaggtttga tactatgtgg tctagtcagt attgtgctgg
    52981 ttcctttgat tcgaaaggat gggggctctg ctatttttgc tcagacgcgt ataggaaaaa
    53041 atggccgcca tttcactttt tacaagtttc gctctatgtg tgtagatgct gaggataaaa
    53101 agagagaact catggaacaa aataccatgc agggtggaat gtttaaggtg gacgatgatc
    53161 ctcgtatcac gaaaattggt cattttatac ggaagacgag cttggacgag ctaccacagt
    53221 tttataatgt tctaaaggga gatatgagtt tggtaggtac acgaccacca acagtggacg
    53281 agtatgaaca ctatacccca gaacaaaaac gtcggctaag ttttaaacct ggtataacag
    53341 gcttatggca ggtcagtgga cgaagtgaaa tcaaaaattt cgatgaagtt gtcaaattag
    53401 atgtggtcta tattgatggt tggacaatct ggaaagatat tgaaatttta ttgaagacag
    53461 ttaaagttgt attgatgaag gatggagcga aatagtttgc ttttgtttca gactattagg
    53521 agaaaaatga agaagtcagt ttatatcatt ggttcaaaag ggattcccgc taagtatggg
    53581 ggctttgaaa cctttgttga gaaattaaca gaatatcaaa aagatggtaa catccaatac
    53641 tatgttgcct gcatgcgcga aaattctgca aaatcaggat ttacagcaga tacatttgag
    53701 tacaatgatg ctatttgtta caacattgat gtgcctaata ttggtcctgc tagagccatt
    53761 gcttatgata ttgctgctgt gaataaagcg attgaaatag ctaagaaaaa caaagatgaa
    53821 gctcctattt tttacattct agcttgtcgt atcgggcctt ttatagctag acttaagaaa
    53881 aagattcaag ctatcggagg tactctgttt gtcaatccag atggacatga gtggcttcgg
    53941 gctaaatgga gcctgccggt tcgaaagtat tggaaatttt cggaacagtt gatggtcaaa
    54001 tatgcagatt tattggtctg tgatagcaaa aatattgaaa aatatatcca gaatgactat
    54061 aagcaatatc aaccaaagac gacttatatt gcttacggga cggatacaag tccgtctatc
    54121 ctgaaatccg aagatctaaa aattcgtagt tggtatcagg aaaaaggact tagcgaaaat
    54181 ggctattatc tagtggtggg acgattcgtc cctgaaaaca actacgaaac catgattcgt
    54241 gaatttatca aatctaagtc caagaaggac tttgtcctca tcacaaatgt ggagcagaat
    54301 aaattttacg accagttgtt acaggagact ggttttgaca aagatcctag ggttaaattt
    54361 gtaggtactg tctatgacca agaattgctt aagtacattc gtgaaaatgc ttttgcctat
    54421 ttccatgggc atgaggttgg agggaccaac ccttctctac tagaagctct agcatccaca
    54481 aaactgaatt tgttgctaga tgttggtttt aaccgtgagg ttggtgaaga cggggctatt
    54541 tattggagaa aagataatct tcataaggtt attgaagaga gtgaacaaaa aacaatagaa
    54601 gaaataaaag aaatagatat tctatctaca gagcaggtag aaaaaagatt tacttgggat
    54661 tttattgtta atgaatatga aaatttattt ttactaggga aataattatc taagttacaa
    54721 ggattttatt tgaggaagct ttgatggaag ttcatcactt tcttagacaa ttatctaaat
    54781 aacttatgtt attcatgaag tttttaaaat gatagatatt ctcccttttt gcaaagatac
    54841 taaaattata gagaggaaat atgcccagta gttgatagtg tttttgggta gggttaaacg
    54901 acatagtttt aagacaaact ggtggagatt taagaaataa gtagttctta ttaaatcaaa
    54961 aacgtgttct tattctatat tgtcatttag tcaaaggtat caagtatgac tattaaaatt
    55021 aattatatgt tttttgtttg tctctctttt ttcggtatag ttttaagtag ttcacaggta
    55081 atagtgaatc tgggtttgtc cagtatagtt c
//
LOCUS       DAVMBH010000008        53805 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVMBH010000008 DAVMBH010000000
VERSION     DAVMBH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 53805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.008"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(154..963)
                     /locus_tag="VYP30_000578"
     CDS             complement(154..963)
                     /locus_tag="VYP30_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1807618.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGIGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(965..1768)
                     /locus_tag="VYP30_000579"
     CDS             complement(965..1768)
                     /locus_tag="VYP30_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1807619.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1778..3265)
                     /gene="tacF"
                     /locus_tag="VYP30_000580"
     CDS             complement(1778..3265)
                     /gene="tacF"
                     /locus_tag="VYP30_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1807620.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3601..4308
                     /locus_tag="VYP30_000581"
     CDS             3601..4308
                     /locus_tag="VYP30_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1807621.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKNIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4313..5335
                     /locus_tag="VYP30_000582"
     CDS             4313..5335
                     /locus_tag="VYP30_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1807622.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5352..6221
                     /gene="licA"
                     /locus_tag="VYP30_000583"
     CDS             5352..6221
                     /gene="licA"
                     /locus_tag="VYP30_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1807623.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6211..7089
                     /locus_tag="VYP30_000584"
     CDS             6211..7089
                     /locus_tag="VYP30_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1807624.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7101..7790
                     /locus_tag="VYP30_000585"
     CDS             7101..7790
                     /locus_tag="VYP30_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1807625.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7876..8724
                     /gene="dprA"
                     /locus_tag="VYP30_000586"
     CDS             7876..8724
                     /gene="dprA"
                     /locus_tag="VYP30_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1807626.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYEPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9607..10650
                     /locus_tag="VYP30_000587"
     CDS             9607..10650
                     /locus_tag="VYP30_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1807627.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10817..12904
                     /gene="topA"
                     /locus_tag="VYP30_000588"
     CDS             10817..12904
                     /gene="topA"
                     /locus_tag="VYP30_000588"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1807628.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13125..13484
                     /locus_tag="VYP30_000589"
     CDS             13125..13484
                     /locus_tag="VYP30_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1807629.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13577..14209
                     /locus_tag="VYP30_000590"
     CDS             13577..14209
                     /locus_tag="VYP30_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1807630.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14253..14909
                     /locus_tag="VYP30_000591"
     CDS             14253..14909
                     /locus_tag="VYP30_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1807631.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14928..15962
                     /locus_tag="VYP30_000592"
     CDS             14928..15962
                     /locus_tag="VYP30_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1807632.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTTPGEYGAIFKYLIENVKTDRQII
                     CSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIHQDGVLKNPLTYEIITPELVGVKIPLGKLSGRHAF
                     VEKLRELALDFTEEDIKPLFAKFKALADKKQEITDADTRALVAGTMVENPEGFHFDDL
                     QLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIFNAIDKFFNQSVRLVSYTIDA
                     VTDGIDAQDRVLVTVENRDIETIFNAAGLDFDVLKASAIAYINANTFVQKENAGEMGC
                     SVSYHDMPSV"
     gene            15974..17011
                     /gene="leuB"
                     /locus_tag="VYP30_000593"
     CDS             15974..17011
                     /gene="leuB"
                     /locus_tag="VYP30_000593"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV1807633.1"
                     /translation="MAKKIVALVGDGIGPEIMEAGLEVLETLAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLVAIGSPQYDGVAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDTERIKRAVETSLAAGILTRDIGGQAST
                     KEMMEAIIARL"
     gene            17008..17277
                     /locus_tag="VYP30_000594"
     CDS             17008..17277
                     /locus_tag="VYP30_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1807634.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17281..17640
                     /locus_tag="VYP30_000595"
     CDS             17281..17640
                     /locus_tag="VYP30_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1807635.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17802..18426
                     /locus_tag="VYP30_000596"
                     /pseudo
     CDS             17802..18426
                     /locus_tag="VYP30_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007122522.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            18589..20272
                     /locus_tag="VYP30_000597"
                     /pseudo
     CDS             18589..20272
                     /locus_tag="VYP30_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042409.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            20447..21433
                     /locus_tag="VYP30_000598"
     CDS             20447..21433
                     /locus_tag="VYP30_000598"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1807636.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEVGRISFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            21497..21568
                     /locus_tag="VYP30_000599"
     tRNA            21497..21568
                     /locus_tag="VYP30_000599"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21530..21532,aa:Arg,seq:ccg)
     gene            21751..22449
                     /locus_tag="VYP30_000600"
     CDS             21751..22449
                     /locus_tag="VYP30_000600"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1807637.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            22440..25979
                     /gene="smc"
                     /locus_tag="VYP30_000601"
     CDS             22440..25979
                     /gene="smc"
                     /locus_tag="VYP30_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1807638.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            25976..26770
                     /locus_tag="VYP30_000602"
     CDS             25976..26770
                     /locus_tag="VYP30_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1807639.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            26770..27588
                     /locus_tag="VYP30_000603"
     CDS             26770..27588
                     /locus_tag="VYP30_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1807640.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            27592..28869
                     /gene="ftsY"
                     /locus_tag="VYP30_000604"
     CDS             27592..28869
                     /gene="ftsY"
                     /locus_tag="VYP30_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1807641.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(28915..30402)
                     /locus_tag="VYP30_000605"
     CDS             complement(28915..30402)
                     /locus_tag="VYP30_000605"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1807642.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(30551..31291)
                     /locus_tag="VYP30_000606"
     CDS             complement(30551..31291)
                     /locus_tag="VYP30_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1807643.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(31291..33456)
                     /locus_tag="VYP30_000607"
     CDS             complement(31291..33456)
                     /locus_tag="VYP30_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1807644.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            33629..34582
                     /locus_tag="VYP30_000608"
     CDS             33629..34582
                     /locus_tag="VYP30_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807645.1"
                     /translation="MKNKRIFKDFQASKMNLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            34659..36647
                     /gene="uvrB"
                     /locus_tag="VYP30_000609"
     CDS             34659..36647
                     /gene="uvrB"
                     /locus_tag="VYP30_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1807646.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            36657..37220
                     /locus_tag="VYP30_000610"
     CDS             36657..37220
                     /locus_tag="VYP30_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807647.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            37186..37674
                     /locus_tag="VYP30_000611"
     CDS             37186..37674
                     /locus_tag="VYP30_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807648.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            37748..38215
                     /locus_tag="VYP30_000612"
     CDS             37748..38215
                     /locus_tag="VYP30_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1807649.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(38212..38727)
                     /locus_tag="VYP30_000613"
     CDS             complement(38212..38727)
                     /locus_tag="VYP30_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1807650.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(38739..39266)
                     /locus_tag="VYP30_000614"
     CDS             complement(38739..39266)
                     /locus_tag="VYP30_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1807651.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(39544..40107)
                     /locus_tag="VYP30_000615"
     CDS             complement(39544..40107)
                     /locus_tag="VYP30_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1807652.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(40091..40642)
                     /gene="coaC"
                     /locus_tag="VYP30_000616"
     CDS             complement(40091..40642)
                     /gene="coaC"
                     /locus_tag="VYP30_000616"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1807653.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(40654..41343)
                     /gene="coaB"
                     /locus_tag="VYP30_000617"
     CDS             complement(40654..41343)
                     /gene="coaB"
                     /locus_tag="VYP30_000617"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1807654.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            41573..43243
                     /locus_tag="VYP30_000618"
     CDS             41573..43243
                     /locus_tag="VYP30_000618"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1807655.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWERVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            43571..44746
                     /gene="mutY"
                     /locus_tag="VYP30_000619"
     CDS             43571..44746
                     /gene="mutY"
                     /locus_tag="VYP30_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1807656.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            44801..45505
                     /locus_tag="VYP30_000620"
     CDS             44801..45505
                     /locus_tag="VYP30_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1807657.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            45498..46847
                     /gene="vicK"
                     /locus_tag="VYP30_000621"
     CDS             45498..46847
                     /gene="vicK"
                     /locus_tag="VYP30_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1807658.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            46849..47658
                     /locus_tag="VYP30_000622"
     CDS             46849..47658
                     /locus_tag="VYP30_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1807659.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            47749..47991
                     /locus_tag="VYP30_000623"
     CDS             47749..47991
                     /locus_tag="VYP30_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1807660.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            47993..48247
                     /locus_tag="VYP30_000624"
     CDS             47993..48247
                     /locus_tag="VYP30_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1807661.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            48294..48989
                     /locus_tag="VYP30_000625"
     CDS             48294..48989
                     /locus_tag="VYP30_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HEV1807662.1"
                     /translation="MKKKWLFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(49338..50324)
                     /locus_tag="VYP30_000626"
     CDS             complement(49338..50324)
                     /locus_tag="VYP30_000626"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1807663.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            50518..52986
                     /gene="gyrA"
                     /locus_tag="VYP30_000627"
     CDS             50518..52986
                     /gene="gyrA"
                     /locus_tag="VYP30_000627"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1807664.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            52986..53729
                     /gene="srtA"
                     /locus_tag="VYP30_000628"
     CDS             52986..53729
                     /gene="srtA"
                     /locus_tag="VYP30_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1807665.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT        16669 a         9379 c        11784 g        15973 t
ORIGIN      
        1 aaaaaagtct ttaaaattat aaaacgcatc atatcaagtt ttttcaaaaa ccttgatatg
       61 atgcgtttta ttgtgggaat atgtatttca ttttctacta aaattatgtt tttgaataac
      121 ctctatctta gtagtttgta taatccccct caatcagttt ttgcgataag ctttaatgct
      181 atgactatac cactcttgca tttcttttga tggtggtgtc atataatcgc catacatctg
      241 ggttaaaaat tggtcatatt ttttgggaac aggcaacata cggccctcaa actcagttaa
      301 aatcagttct ttaaaggtat caactgggaa gatttctttc atcccttcct taccgatccc
      361 aattcctcct tcatattgag gagtgttggt tacagcattt ttgactagtt gatcaatttt
      421 cttgtaaaag tagcgaggat tgacaaatcg gagagcgtac cagctacata atctaagaaa
      481 atcttttagt ttgctatcac cgtgaactgc tcgtgatttt ttgatataag ctagttgacg
      541 aagagccaca tacttatagc tcttgtcgac aatactcaag tctgtaaatc gatcaattgg
      601 gaagacatcg atgaaaaggc tggtatcatg acgcttgtac ttaacatggt cttctataac
      661 agtagaagtg tccaaaatcg atgcgaaatt atggaagtac caagaagatg tatcgtagga
      721 aagaaccttg tagcgagggt gattttcttc ttcaataatc ttcagtaaac gctcataatc
      781 ctcacgataa agggaaatat caatatcatc atcccaagga atcatacctt tgtggcggat
      841 ggctccaagc atggttccat aactgagaaa ataaggaata tcatgtttct tacaagtctc
      901 atcaatatag tccagcaggg ctagttgaat ttctttaatt tctttttttt ctaaatattg
      961 catcctaatc ctccaattta taagcgtgaa attcatgact gtagaagcgt ttttcttctg
     1021 gtggtagggt catataatct ccataaaatt gtgtcaaaat agtatcaaat ttttcaggtg
     1081 caggaaggct taaattctca aagggtaaat cgattgtttt atcaaaggta ccacttggga
     1141 agacttcctt ttccttaaat tttgaaggga taaaagccat atattgccca ttttcacgac
     1201 tatatttttg aatttctttc tcgattttat ttgcaaaata acgaggagaa accggtcgaa
     1261 ggagtaacca gaaggctgtt cgtatccaat cttttaaaag gctatcctta tagacaatat
     1321 ttttatgttt actgaaagac agcagtttga agctttccag tttataacaa gtatcaatga
     1381 ccttaggatc atcaaagcga tctataggga aaatatcgat aaagatacca gactcatagg
     1441 tttttgtatt tcgagtatca ataattttag tcgtactgtc ggttatcttg ataaagttgt
     1501 taaagtagtt cttatcagtt tctaaggata ggagcttata cttgcttttt tccttttgaa
     1561 aaatgttaat aaatcgttgg tagtcttctc taggcatgga taaatcaata tcgtcgtccc
     1621 aagggataaa gccctcatgt cgaaccgccc caatcagagt gccgtagtta ataatatagt
     1681 tgatattgtg ctttttacag agagtatcaa tataattcaa aatttctaat tcaatttgtt
     1741 tggcatcttc aacggttagt tgtttcattt taaactccta agatttttta aatttatttt
     1801 ttaaggctag gacatggttt aaaaattcat agaaaatgct atcttttgtg aagacaagta
     1861 gactaatata agagatagct gatagcaaga caatcaaacc agtattaatc aaaaatggca
     1921 aattaatgac catatccaca ggatacacga aattaatcag gaaataaatt gctacaaagg
     1981 aaagtgaaaa gagagagtat cgaacagtat agctaaagat atgtcccaag tggatgagtt
     2041 gttttctatg gatgaaaatg atatagaaaa caagtagaga agcctctgat aacatagttg
     2101 tcagtaagta gtattcggga gccacgatat ggttgaaaaa gaggagacta ttcaagccca
     2161 aattgagtag cccagcaaag actgtataga ctgtgatacg tttttcatag ccattggtaa
     2221 agagaatttg ggaaccaaga atggtatcta aggccagaat aatcgtacga aaagcgaaga
     2281 gagaggtcaa gatgccgcct ccgatatatt tttcactacc gtaaagtagg atggcatttg
     2341 gtcctaaaac catgagtcca aaactcagtg gaatgataaa gaagttaaag attcgactac
     2401 ctctattaac cagagaaaca taggcttctt tgtctccttt ccccagatag taactgagac
     2461 gaggcacact cactccaatt gcacctgtta caaccccagc tataacggtc acaattcgct
     2521 gagctatggt atagtaacta acgttgacat caatccctgt tttaacgagg aagaggcgat
     2581 ctaaaaaagt gaagagcata ttggcattgg caaagactaa catggctgtc agagggagaa
     2641 agagtggttt aaaatcactt aggtgaatct taacaagttt gatgtctctt ttaatccaaa
     2701 aataactaat caggtagtta atcagcgtcg ataaactcat cacaagtgta tagacaacaa
     2761 tatcgtgttc atttttaaca aataagaaaa tagagaccag catcaggata cggatgaagg
     2821 cagttttgta aaagagaaaa ctgtaatttt ccagagcttc attgacccat tcgattgaaa
     2881 aaatctgggc aatgagttga atccccataa caaggtagac ctttttgacg attggattat
     2941 cagtaaagaa gagaggatag gctaggatat agacagcagt ggtcaaaatc gtacaagcga
     3001 tgcacaaata aaaaagacta gaaaaggttc tgttaagatc ttttttgtta tccttgacat
     3061 tactgatagc ccttaaaccg tagttataga caccataagt tgcaaagggc aagaaaaatg
     3121 acaaaatagt gtcgactgag ttgaagtaac catagtcagt tcggtccaag acacgcgcga
     3181 cataggttcc agttaggatg ggaaaaataa tattcaagac acgaattccc atgtaagata
     3241 gagcatttaa ttttatactt ttcattcaat ttacctcgtt tttcattata tcataaagtt
     3301 agctaataag aaatgaaggg cagtaagtca agtaatcact ttgaagtttc aaatcttaag
     3361 ttttaagttt tctttaagga aagtatatta ttctgaagga ctctaaaatt tcgcagccat
     3421 ttattagtaa ttgctacaga attcctagtc attactagaa atggactagt ttcttggaat
     3481 aatagaactg cataattctc ctattctaga aggggaggac cagtatttct tttatgatag
     3541 gactagattg tggtataata gagagaataa gtttttttag taagacaaag gagaaaatag
     3601 atgatttatg caggaattct tgccggtgga actggcacac gcatggggat cagtaacttg
     3661 ccaaaacaat ttttagagct aggtgatcga cctattttga ttcatacaat tgaaaaattt
     3721 gtcttggagc caagtattga aaaaattgta gttggtgttc atggagactg ggtttctcat
     3781 gcagaagatc ttgtagataa atatcttcct ctttataagg aacgtatcat cattacaaag
     3841 ggtggtgctg accgcaatac aagtattaag aacatcattg aagccattga tgcttatcgt
     3901 ccgcttactc cagaggatat cgttgttacc cacgattctg ttcgtccatt tattacactt
     3961 cgcatgattc aggacaatat ccaacttgcc caaaatcatg acgcagtgga cacagtggta
     4021 gaagcggttg atactatcgt tgaaagtacc aatggtcaat ttattacaga tattccaaat
     4081 cgtgctcacc tttatcaagg acaaacacct caaacattcc gttgcaagga cttcatggac
     4141 ctttatggat ctctttctga tgaagagaag gaaatcttga cagatgcatg taaaatcttt
     4201 gtgatcaaag gaaaagatgt ggctttggcc aaaggtgaat actcaaatct gaagattaca
     4261 accgtaacag atttgaagat tgcaaaaagt atgattgaga aagactagta aaatgattaa
     4321 tcaaatttat caactaacta agcctaagtt tatcaatgtc aaatatcagg aagaggctat
     4381 tgaccaagag aatcatatcc ttatccgtcc caactacatg gctgtctgtc atgcggatca
     4441 gcgttactat cagggaaaac gtgatcccaa gattttgaat aaaaagcttc caatggcaat
     4501 gattcacgag tcatgtggaa ccgtcatttc tgacccgacc ggaacctacg aggttggtca
     4561 aaaagttgtc atgattccca atcagtctcc tatgcagagt gatgaagaat tctatgaaaa
     4621 ctacatgaca gggacccatt tcttgtctag tggatttgat ggctttatga gagagtttgt
     4681 ttctctccct aaagatcgtg tggtggctta tgatgctatt gaagatacgg ttgcagccat
     4741 tacagagttt gtcagtgtgg gcatgcacgc tatgaatcgt ctattgactc ttgctcatag
     4801 caagcgggag cggatcgccg ttattggaga tggaagttta gcttttgtgg ttgccaatat
     4861 tatcaactat actttgccag aagcagagat tgtggttatt ggtcgtcatt gggaaaagtt
     4921 ggaactcttc tcatttgcca aagaatgcta tattacggat aatattcctg aagatttggc
     4981 ctttgaccat gcttttgaat gttgtggtgg tgatggtact ggaccagcta ttaatgactt
     5041 gattcgctac attcgtcctc agggaacgat tctcatgatg ggagttagcg aatataaagt
     5101 caatctcaat actcgcgatg ccttagaaaa gggcttgatt ttggttgggt catctcgttc
     5161 tggtcgcatt gattttgaaa atgctatcca aatgatggaa gtcaagaaat ttgccaatcg
     5221 tcttaaaaat atcctttatc tagaagaacc tgtaagagaa attaaagata ttcatcgtgt
     5281 ctttgcaacc gatttaaaca cagcctttaa aacagtgttt aagtgggaag tataagtact
     5341 ggaggttaat tgtggagaaa atcattaaag aaaaaatttc ttccttactt agtcaagaag
     5401 aggaagtcct cagtgttgaa caactgggtg gaatgaccaa tcaaaactat ttggccaaaa
     5461 caacaaataa gcaatacatt gttaaattct ttggtaaagg gacagaaaag cttatcaatc
     5521 gacaagatga aaagtacaat cttgaactac taaaggattt aggcttagat gtaaaaaatt
     5581 atctttttga tattgaagct ggtatcaaag taaatgagta tatcgaatct gcgattacgc
     5641 ttgattcaac gtcaatcaag accaagttcg acaaaattac tccaatatta caaactattc
     5701 atacgtctgc taaggaatta agaggagaat ttgctccttt tgaagaaatc aaaaaatacg
     5761 aatccttgat tgaagaacaa attccttatg ccaactatga atctgttaga aatgcagtct
     5821 tctccttaga gaaaagactg gctgacttag gtgttgacag aaaatcttgt catatcgatt
     5881 tggtgcctga aaactttatc gaatcacctc aaggacgact ttatttgatt gactgggaat
     5941 attcatcaat gaatgatcca atgtgggatt tggctgccct ctttttagag tctgaattca
     6001 cttcccaaga ggaagaaact ttcttatctc actatgagag tgaccaaaca ccggtttctc
     6061 atgaaaagat tgctatttat aaaattttac aagatactat ttggagtcta tggactgtct
     6121 ataaggaaga gcaaggtgaa gattttggtg actatggtgt gaatcgttac caaagagcta
     6181 ttaaaggttt ggcttcttat ggaggttcag atgaaaagta aaaacggagt tccttttggc
     6241 cttctctcag gtattttctg gggcttgggt ctaacggtta gtgcttatat cttttcgatt
     6301 tttacagatt tgtcaccctt tgtggtggct gcaactcatg attttttgag catctttatc
     6361 ttactagctt ttctcttggt aaaagaaggg aaagttcgcc tctcaatttt cttaaatatt
     6421 cgcaatgtca gtgttatcat aggagccttg ctagcaggcc ctatcggtat gcaggccaat
     6481 ctttatgcag ttaagtatat cggaagttct ttagcttcat ctgtatcggc tatttaccct
     6541 gcgatttcag ttctattggc tttcttcttt ttgaagcaca agatttcgaa aaatactgta
     6601 tttgggattg tcttgattat tggagggatt attgcccaga cctataaggt tgaacaggtt
     6661 aattctttct acattgggat tctttgtgct ttggtttgtg ctattgcatg gggaagtgag
     6721 agtgttctta gctcttttgc catggaaagc gaattgagtg aaatcgaagc cctcttaatc
     6781 cgtcaagtaa cttcgttctt gtcctatctt gtgattgtgc tcttctctca tcagtcattt
     6841 gttgcagtag ccaatggaca attgctaggt ctcatgattg tctttgtagc ctttgatatg
     6901 atttcctatt tggcttatta tatcgctatc aatcgcttgc aaccagccaa ggctacaggc
     6961 ttgaacgtga gctatgtagt atggactgtc ttgttcgcag ctcttttctt gggaacatca
     7021 ttagatatgc tgaccattat gacgtcactt gtcgtcattg ctggagttta tattattatt
     7081 aaagaataaa ggagattcgt gtgaaagcca ttatcttagc agcgggattg ggaactcgct
     7141 tgcgtcctat gactgaaaat acccctaaag ccttggttca ggttaatcaa aaacctttga
     7201 ttgaatacca aattgagttt ctcaaagaaa aaggaatcaa tgacatcatc atcatcgttg
     7261 gttatcttaa agaacaattc gattatttaa aagaaaaata cggtgttcgc ctcgttttca
     7321 atgataaata cgctgactac aataactttt actctctcta tcttgtaaaa gaagaattgg
     7381 ccaacagcta tgttattgat gctgacaatt atctctttaa aaatatgttc cgcaatgatt
     7441 tgacacgttc gacttatttt agtgtttatc gtgaagattg taccaacgaa tggttcttgg
     7501 tctatggaga tgactacaag gttcaagaca ttattgttga tagcaaggca ggtcgcatcc
     7561 ttagtggtgt atccttctgg gatgctccaa ctgcagaaaa gattgtcagc tttatcgaca
     7621 aggcttatgc aagtggtgaa tttgttgatc tctactggga caatatggtt aaggataata
     7681 tcaaagagct agatgtctat gttgaagaat tagaaggcaa tagcatttat gagatcgata
     7741 gtgtccaaga ctatcgtaaa ttagaagaaa ttcttaaaaa cgaaaattaa agattccaac
     7801 atctgacaaa atagtcggat gttttttgat tttttacgaa tagatagatg agtagaaaaa
     7861 gaaatggagt tatttatgaa aatcacaaac tatgaaatct ataagttaaa aaaatcaggt
     7921 ttgaccaatc aacagatttt gaaagtgcta gaatacggtg aaaatgttga tcaggagctt
     7981 ttgttgggtg atattgcaga tatctcaggt tgccgtaatc cagccgtttt tatggaacgt
     8041 tattttcaga tagacgatgc gcatttgtcg aaagagtttc aaaaatttcc atctttctct
     8101 attttagatg actgttatcc ttgggatttg agtgaaatat atgatgcgcc tgtactttta
     8161 ttttacaagg gaaatcttga cctcctgaaa ttcccgaagg tagcggtcgt gggcagtcgt
     8221 gcttgtagca aacagggagc taagtcagtt gaaaaagtca ttcaaggctt ggaaaatgaa
     8281 ctggttattg tcagtggtct ggccaagggc attgacacag cagctcatat ggcagctctt
     8341 cagaatggcg gaaaaaccat tgcagtgatt ggaacaggac tggatgtgtt ttatcctaaa
     8401 gccaacaaac gcttgcaaga ctacatcggc aatgaccatc tggctctaag tgaatatgaa
     8461 cctggcgaac aacctctgaa atttcatttt cctgcccgta atcgcatcat tgctggactt
     8521 tgtcgtggtg tgattgtagc agaggctaag atgcgttcag gtagtctcat tacctgtgag
     8581 cgagcaatgg aagaaggacg cgatgtcttt gctattcctg gtagcatttt agatggacta
     8641 tcagacggtt gccatcattt gattcaagaa ggagcaaaat tggtcaccag tgggcaagat
     8701 gttcttgcgg aatttgaatt ttaaaaatga cctaagctag aattctaaga aaaaatcaat
     8761 tttaagagaa aatgaaccca acatttccat aataaaacgc atattagcaa gtttttaaca
     8821 cttgataata tgcgtttttt ctaagtggat tagtagagta gaggattttt tcatataata
     8881 ctcttcgaaa atctcttcaa actacgtcag cttccatctg caacctcaaa acagtatttt
     8941 gagctgactt cgtcagtctt atctacaacc tcaaagcagt gctttgagca acctgtggct
     9001 agcttcctag tttgcgcttt gattttcatt gagtataagg gaaagtatag tgaattgaaa
     9061 taagatgtga acaactctat caggaaagtc aaattaattt atagaaatat tttagcagcc
     9121 aaggtgcact gttatagatt caatacacta taatttagtg taattgagaa aggagaaatg
     9181 attgtgattg atgttggcta ggttatgttc aatgattcct accgtctcaa atcttgtcag
     9241 taaggaaaaa taaattcttc aaaagtagag attacaaggc ttgtttaaga aagaattcaa
     9301 agaccttgac aaataaaaat aaaatggtta ttataagaaa tggtctaaaa tagatgatga
     9361 tacttttcga aaatcttttt acgtcagctc agctttgcct tgctgtgttt tgagcaagct
     9421 acggttagct tccgagtttg attttcattt actagaaatg aaactgatga gagatatcag
     9481 tagacatttg agtcaggata ttatggaaaa tgataaaaag agctcgtgag attggcatat
     9541 cagactacta aagtattgag tttgttagga ttttagcgac tagttagctg ggaaaggaag
     9601 atatttgtga caaataataa actgtattcg ttgatagaat ttagaaataa aatatatgaa
     9661 gaattagaac tttccagaag tgatttagcg attttactat gtgccatgct tatcgcctct
     9721 atcggattaa atatggattc gactcccgtg attattggag ccatgttaat ctctcctttg
     9781 atgacaccta ttctgggagt ggggctctct ctagctatat ttgattttaa attgttaaga
     9841 aaatctttta aaatattagc tattcaaatt cttgccagtc taatagcttc aacactttat
     9901 ttttatcttt ctcccatttc gtatgctagt tcggagattg ttgctagaac ctctccgact
     9961 atttgggatg ttctcattgc ttttgtagga gggatagcag gtattattgg tgctaggaaa
    10021 aaagagacca ataatattgt tcctggtgtt gctattgcaa ccgccttgat gcctcctctt
    10081 tgtacagtag gttatgctat tgcttctgct aatctaaaat ttatcatagg ctcctcttac
    10141 ctattcctca tcaattgtag ctttattgtc attgcgactt atataggtgt taggttgatg
    10201 atggttaaga aacattattt taaagataat gaagaagact ctaaaatgcg taggattttg
    10261 cttctagttg ctgttttgct gatgattccg agtttcatct ctgcaacgac tttagtgaga
    10321 gaaacgttga aaaaagagtc ccttaagaaa tttatatcag agcagtttca ggggtataat
    10381 attttgaaaa aaacctattc taaaaagact cataccctaa agctaaccat ttcaggaaat
    10441 tatttgacag aagaagaact cgatatgatt tcaagtaaga gaggtgacta tggtttaagt
    10501 gatgtttctg ttcaagtttc acaattgtct gattcagaac aacttagtaa ggaagagctg
    10561 gtggagtatt tcttccagta tatcaaggat aaggaagcaa aagaaaagga gaaagccaat
    10621 aaatttgata cagagtctga ggagcaataa tttcttgaga atagctggtt tctctcgtga
    10681 gtcttctatg tatatcaaag gaagactgag gttttaagta taaaactttt cttctattat
    10741 agtagctaag tcttgacagg gttcaaaaaa tggtttacac tttataaagt ttattacttt
    10801 gaaaaggtgt gatactgtgg ctacggcaac aaaaaagaaa aaatcaacag ttaaaaaaaa
    10861 tctagtcatc gtggagtcgc ctgctaaggc caagacgatt gaaaaatatc taggcagaaa
    10921 ctacaaggtt ttagccagtg tcgggcatat ccgtgatttg aagaaatcca gtatgtccgt
    10981 cgatattgaa aataattatg aaccgcaata tatcaatatc cgaggaaaag gccctcttat
    11041 caatgacttg aaaaaagaag ctaaaaaagc taataaagtt tttctcgcga gtgacccgga
    11101 ccgtgaagga gaagcgattt cttggcattt ggcccatatt ctcaacttgg atgaaaatga
    11161 tgccaaccgt gtggtcttca atgaaatcac caaggatgca gtcaaaaatg cttttaaaga
    11221 acctcgtaag atcgatatgg acttggtcga tgcccaacaa gctcgtcgga tcttggatcg
    11281 cttggtaggg tattcgattt cgcctatttt gtggaagaag gtcaagaagg gcttgtcagc
    11341 aggtcgcgtt cagtccattg cccttaaact catcattgac cgtgaaaatg aaatcaatgc
    11401 cttccagcca gaagaatact ggacagttga tgctgtcttt aaaaagggaa ccaaacaatt
    11461 tcatgcttcc ttctatggag tagatggtaa aaagatgaaa ctgaccagca atgacgaagt
    11521 caaggaagtc ttgtctcgtc tgactagtaa agacttttca gtagatcagg tggataagaa
    11581 agagcgcaag cgcaatgctc ctttacccta taccacttca tctatgcaga tggatgctgc
    11641 caataaaatc aatttccgta ctcgaaaaac catgatggtt gcccaacagc tctatgaagg
    11701 aattaatatt ggttctggtg ttcaaggttt gattacctat atgcgtaccg attcgactcg
    11761 tatcagtcct gtagcgcaaa atgaggcggc aagcttcatt acggatcgtt ttggtagcaa
    11821 gtattctaag cacggtagca aggtcaaaaa cgcatcaggt gctcaggatg cccatgaggc
    11881 tattcgtccg tcaagtgtct ttaatacacc agaaagcatc gctaagtatc tggacaagga
    11941 tcagctcaag ctatataccc ttatctggaa tcgttttgtg gctagccaga tgacagcggc
    12001 cgtttttgat accatggctg ttaaattgtc tcaaaatgga gttcaatttg ctgccaatgg
    12061 tagtcaggtt aagtttgatg gttatcttgc catttataat gattctgaca agaataagat
    12121 gttaccggac atggttgttg gagatgtggt caaacaggtc aatagcaaac cagagcaaca
    12181 tttcacccaa ccgcctgccc gttattctga agcaacactg attaaaacct tagaggaaaa
    12241 tggggttgga cgtccatcaa cctatgcgcc aaccattgaa accattcaga aacgttatta
    12301 tgttcgcctg gcagccaaac gttttgaacc gacagagttg ggagaaattg tcaataagct
    12361 catcgttgaa tatttcccag atatcgtaaa cgtgaccttc acagctgaaa tggaaggtaa
    12421 actggatgat gtcgaagttg gaaaagagca gtggcgacgg gtcattgatg ctttttacaa
    12481 accattctct aaagaagttg ccaaggctga agaagaaatg gaaaaaatcc agattaagga
    12541 tgaaccagct ggatttgact gtgaagtgtg tggcagtcca atggtcatta aacttggtcg
    12601 ttttggtaaa ttctacgctt gtagcaattt cccagattgc cgtcataccc aagcaatagt
    12661 gaaagagatt ggtgttgagt gtccaagctg tcatcaggga caaattattg agcgaaaaac
    12721 caagcgtaat cgcctattct atggttgcaa tcgctatcca gaatgtgaat ttacctcttg
    12781 ggacaagcct gttggtcgtg actgtccaaa atgtggcaac ttcctcatgg agaaaaaagt
    12841 ccgtggtggt ggcaagcagg ttgtttgtag caaaggcgac tacgaggaag aaaagattaa
    12901 ataagaggag gggcccgaaa gtaaatttca ggctcctttt ggttagaact tgacaaaata
    12961 catcatttta tgcgaaacta gaagaagatt attttatact caatgagaat caaagagcaa
    13021 attagaaagc tagtcgcagg ttgctcaaag cactactttg aggttgaaga tggaagctga
    13081 cctggtttga agagattttc gaagagtatt aactaggaga agttatgcgt cttatctatc
    13141 tgataattgg ttttttatca ctggccttgg ctattgttgg ggttgtttta cccttgttgc
    13201 cgacaacgcc tttccttttg ttgtctattg cttgtttctc cagaagttcc aagcgtttcg
    13261 aagactggct ttatcatacc aagctctatc aaacatatgt agctgatttt cgcgagacta
    13321 agtctattac gcgtgaacga aagaaaaaaa tcatcgtctc tatctacgtc ttgatgggaa
    13381 tttctattta ttttgcacct cttttaccag tcaaaatcgg tctgggtgct ttgaccatct
    13441 ttattactta ttatctcttc aaggtcattc cagacaaaga atagttaaaa cagtagttat
    13501 ttgccttgat aaaattgaaa gcatattcat aacaatatga tataataaat ttgaagtaat
    13561 attcaaggag aatcaaatga tttacgaatt ttgtgctgaa aatgtgactt tacttgaaaa
    13621 agcgatgcag gctggagctc gtcggattga actctgtgat aatctagcag ttggtgggac
    13681 aacacccagc tatggagtga ctaaggcagc ggttgaactg gcagctaact acgatacaac
    13741 catcatgacc atgattcggc cacgtggtgg tgactttgtc tataatgact tagaaattgc
    13801 tatcatgcta gaagacattc gtttgactgc tcaggctgga agtcaagggg ttgtatttgg
    13861 agctttaact gctgataaaa agttggataa gcctaatctg gaaaagttaa ttgctgcatc
    13921 aaaaggaatg gaaattgtct ttcacatggc ctttgatgaa ctaagtgatg aagatcaacc
    13981 ggaagctatt gactggctca gtcaagccgg tgtcactcgt atcctaactc gtgctggtgt
    14041 gtctggcgac tccttagaaa aacgttttgt tcactatcac agaattttgg agtacgctaa
    14101 aggtaaaatt gaaattctac caggtggggg gattgacctt gaaaaccgtc aaacctttat
    14161 cgaccaggtg ggggtaacac aattgcatgg tactaaggtt gttttttaaa aaatagaaag
    14221 gaactgctag ctttgggtag cagttttcac ttatgtttga aatttttaaa tcctatcaat
    14281 ttaatcaaga aaaggctcat gattatggtt ttatagaaaa tagcgaagtc tggacatata
    14341 gttgccagat tttgcaaggt gactttgtca tgactgtgtc catcactgct gataatgtga
    14401 actttcaagt ctttgaccaa gaaactggtg acctctatcc tcacgttcat atggaaagca
    14461 tgaggggaag ttttgtcgga aatgtccgtg aggcttgtct ggagattctt taccagattc
    14521 ggaaggcttg ttttgatgtg caagatttta tctgtcatca gactaagcgt atcatgactc
    14581 aagttcagga aaagtatgga aaccagttgg agtatctgtg ggaaaaatcg cctgatacag
    14641 ctgtattgcg ccatgaaggc aatcaaaagt ggtatgccgt cttgatgaaa atctcttgga
    14701 ataagctgga aaagggaaga gaaggacaag tggaagcagt caacctcaag catgaccaag
    14761 tagctaattt actttcacaa aaggggattt atccagcctt tcatatgagc aagcgctact
    14821 ggattagtgt gtcccttgat gatactttat cagatgaaga agtactggaa ttgatagaaa
    14881 aaagttggaa cttaacctct aaaaaatgaa atattttaat aattttcatg aactttcaat
    14941 tagctaaata ttctttactg aagaaatttt cagaaaatat agaatttacc acaccagggg
    15001 aatatggtgc catcttcaaa tacctgattg agaatgtcaa gacggatcgt cagatcatct
    15061 gttcgcctca ctgtcatgat gacctcggaa tggcagtggc aaatagcctt gctgctgtca
    15121 agaatggtgc aggacgtgtt gaagggacta tcaatggtat tagggagcga gctggaaatg
    15181 ctgctttgga agaaattgca gtggctctca atattcgcca agattactac caagtagaaa
    15241 ccagtattgt cctaaatgag accatcaata cgtcagaaat ggtttctcgt ttctctggta
    15301 ttcaccaaga tggagtcctt aaaaatcctc tcacttatga gatcatcaca cctgaattgg
    15361 ttggtgttaa gattccgctt ggaaaattat ctggtcgcca tgcttttgtt gagaaactga
    15421 gagaattggc cctagatttt acagaagagg atatcaaacc actctttgct aagttcaagg
    15481 cactggccga taagaagcaa gaaatcacag atgcagatac tcgagctttg gtagctggaa
    15541 ccatggttga aaatccagaa ggcttccact ttgatgattt acaacttcaa actcatgcag
    15601 ataatgacat tgaagcgctc gttagcctag ccaatatgga tggtgagaaa gtcgaattta
    15661 atgcgacagg gcaaggttcc gttgaagcaa tctttaacgc tatcgataag ttctttaacc
    15721 aatctgttcg tttggtgtcc tacactatcg atgcagtaac agatggaatc gatgcccagg
    15781 atcgggtttt ggtcactgtt gaaaacagag atatagaaac catctttaat gcagcagggc
    15841 ttgattttga tgtgttgaag gcttctgcta ttgcctatat aaacgctaat acctttgttc
    15901 aaaaagagaa tgcaggtgag atgggatgca gtgtttctta ccatgatatg cctagtgtgt
    15961 aaaggagaag gctatggcaa agaaaatagt agctctagta ggagacggaa ttggcccaga
    16021 aatcatggag gctggtttag aagttctgga gactctagct gaaaaaacag gttttgacta
    16081 tgagattgac agacgaccgt tcggaggtgc agatattgat gcagcaggac ctcccttacc
    16141 tgatgaaacc cttaaggcaa gtagggaagc agatgctatc ctactagtag ctatcggtag
    16201 tcctcagtat gatggagtag cggttcgccc tgaacaaggc ctgatggctc tccgtaagga
    16261 actcaatctt tacgctaata ttcgtcctgt aaaaatcttt gacagtctca agtatttgtc
    16321 accactcaaa ccggaacgaa tttctggtgt agactttgtc gtggtgcgtg aattgacagg
    16381 cgagatttac tttggagatc atattcttga agagcgcaaa gcgcgtgata tcaacgacta
    16441 tagctatgag gaagtggagc ggattattcg caaagccttt gaaattgcaa gaaatcgcag
    16501 aaaaatcgtt actagtatcg ataagcaaaa tgttctagcg acctcaaaac tctggcggaa
    16561 agtagctgag gaagtcgcac aggatttccc agatgtaacc ttggaacacc agctggtaga
    16621 ctcagctgct atgcttatga ttaccaatcc tgctaagttt gatgttattg taacggagaa
    16681 tctttttgga gatattttat ctgatgaatc aagcgtctta tctggtacac ttggggttat
    16741 gccatcagcc agtcattctg aaaatggacc aagtctctat gaacctattc acggttcagc
    16801 acctgatatt gcaggtcaag gaattgccaa tcctatttcc atgattttat cagttgtcat
    16861 gatgttgaga gatagtttcg gacgttatga ggatacagag cgtatcaaac gtgctgttga
    16921 gacaagtctg gcggcaggaa ttttaacgag agatatagga ggtcaggctt caacaaagga
    16981 aatgatggaa gctattattg caaggttatg aagttagacg aaaaaattac tctagtcctt
    17041 ttgatttgga atgtcatcat tttcttgatt tatggcattg acaaattcaa ggcaagaaga
    17101 agagcttggc gcatccaaga gaaaatctta ctcattttag cccttacttg tggtggtttt
    17161 ggggcctggt tagctggaat cacttttcac cacaagactc gaaaatggta ctttaaaaca
    17221 gtttggtttc ttgggatggt gaccacacta gtagccttat attttatttg gaggtaatgg
    17281 atggcagggt cttcgaggga acacgctgct tgggctctag cgaactatgg ttttaaggtc
    17341 gtgattgcag gaactttcgg tgacattcat tacaataatg aactcaataa tggcctgttg
    17401 ccaatcgttc agcctagaga ggttagagag aaattagccc agctaaaacc aaccgaccat
    17461 gtaactgtgg acttggaaca acaaaaaatc atctcaccag ttgaagaatt caccttcgag
    17521 atagatagcg agtggaaaca taaactccta aatagtttgg atgatatcgg tattaccttg
    17581 cagtatgaag agttgattgc tgcttatgaa aaacaacgac cagcctactg gcaggattag
    17641 aaaaaataga aaaggaaata tagtaaactg aaataagatg taaacaaatg aattggagct
    17701 taacatccat ttccagcaat tttttagaaa ctacagtgga ctattctgga ttcaacacat
    17761 tataaaatta tgacaaaaca cattcacaag aaggctacga cattttaaaa ggtgagggcg
    17821 gatgtatcgc ttgccctact aaagttggtt acattatcat gaccagcaac aaggcagaac
    17881 ttgagcgtaa gttcgcagcc aaagaacgta agcgtaacaa accaggtgtt gttctctgcg
    17941 gtagcatgga tgaacttcgc gctttagcgc aactcaaccc agaaattgaa gcattctact
    18001 aaaaacattg ggatgaagat attcttcttg gttgtatcct tccttggaaa ccagaagcct
    18061 ctgaaaaact caaagcatac ggggatggcc gtgaagaact tatgactgat gtacgtggta
    18121 ctagctgttt tgttatcaag tttggaaaag caggtgaaca attggctgcc aagctttggg
    18181 aagaaggtaa aatggtctac gcctcatctg cttcaatgac aaaacgattg aaactcgcta
    18241 tgagagcaag gtgtaatggt gtctatggtc gataaggatg gcaaactcat cccagaacaa
    18301 ggaggagcac gttcaacctc accagcacca gttgtgatcc gtaaagggct tgacattgat
    18361 aaaatcatga tgcacctgtc agatactttt aactcatggg actaccgtca ggttgagtat
    18421 tattaggata gagaagaagt ctagtgttaa ggacattaca gctcataata ctaggctttt
    18481 ttatagaaat tcttttcttt ttctatagga tatggtattc tatgtagaaa atatatgtta
    18541 ataagtaatg ccaatattta aacatcatta gtaaaaggag ttagattgat gaataaaaga
    18601 aaagttagtt tagaagattt ttataaatgg tatagtctaa ataaagaaga gttattaaat
    18661 aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag aagagtttct ccaggaatgg
    18721 cctttggata ggattttaac aatgtcaatc gatgaatatg taataggaaa gggacagcaa
    18781 aataagtctt tatgctacgc tcttgagaag ggaaaataca aaaatctatt tcttggaatt
    18841 tctggtggct cagcttcaaa atttggtatt tattggaata aaaaaacaaa caaatataaa
    18901 gatcaagcta ataatgagat ttcagagttg gatcagcgat tttcaaaatt aaaatcagat
    18961 ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg aaaatcctat ttttgatatg
    19021 aaaagatcaa caaatgaatt tattggtcgt tctgctatgg tgacaaaatt actttgtatc
    19081 tattctgagg gagatccttt ctttggtgta aatattaata gtcagaaaga attttggaac
    19141 cactttgttt ctcagacaaa tcaaggtgga ccttatctgc aaaatcataa aataattgaa
    19201 ctggtgtcca aaacttatcc tgagttggag ccatcgaaat taggaactat gctttttgag
    19261 tattctaagc tttttatgga aaataaagga agacaatagt acaatggatt catcaaacaa
    19321 ttttcgtcat caattaactc aatctctatt aaagtctcca aaccttatcc ttcgtggtgc
    19381 tcctggcaca ggaaagactt atcttgctaa agaaattgcc aaagaattaa cggatggcaa
    19441 cgaagatcaa atcggatttg tacaatttca cccatcatat gattatacgg attttgtaga
    19501 aggtttaaga ccagtatcaa atggggatgg agctattgag tttaggctac aggacggtat
    19561 ttttaaagat ttttgtcaga aagcaaaaga aacccaattg attggaggac aagataattt
    19621 tgatgaggct tgggattctt acttagaata tataaatgtt gctgaagaaa aagaatatat
    19681 aacaaaaaca tcttacttat ctgttaatag tagacaaaat ttgtcagtaa attatgatag
    19741 tggtgttcca ggatggtcac tacctagcaa atatgtttac gagttgtata aagataaaaa
    19801 ttataataag caagaatact acaaaagtgg tggaaaaact gtcctagaaa cattgagaaa
    19861 gagatttggt ttgaaagact atgtttcccc aacagaaatt gatactgata agaaattcgt
    19921 cttcatcatc gatgaaatca atcgtgggga gatttctaag atttttggcg aactcttttt
    19981 ctctatcgac cctggctatc gtggtgaaaa aggaatcaac cgtgaggact tattccagct
    20041 gatttcctat tcttatattt taaaagctga gaaggctgga ctgatttttc ctagtatgga
    20101 gcagtcagta aatagtgaaa taggaaaagt agctggctat ggagctcaat tgaagaagtg
    20161 gtctattcga atccctcaga atgcctcatt ctatagtaca ttttgtaaaa tgatggaaaa
    20221 ttcagaagaa aattttaaag cgattattga tgaagaagtg gggagaaaat aatttcccct
    20281 ctttctttta tttttaacac aagtaaaacc cgaacgatat attttaattc ataaaataat
    20341 ttgacaaaaa ctgtactttg atttataata aattaaggaa acgtcggaaa aggcgtagtg
    20401 atgcaagagc ataggtaggt cattacaaaa gaaacgagac atcgatatgt taaatgaatt
    20461 tccaattttt gattacgaag atattcaatt gattccaaat aaatgtgtca ttaaaagccg
    20521 tgcagaagcg gatacaagtg tcactttagg aaatcacacc tttaaactac ctgttgtgcc
    20581 agcgaatatg cagacgattt tggatgaaaa tgtagcagag caactggcta aaggtggtta
    20641 cttctacatt atgcaccgtt ttgatgaggt aggacgcatt tcttttatta aacgaatgca
    20701 cgatcaaggg ctcattgctt ctatctctgt cggtgttaag gattatgagt atgattttgt
    20761 tagccagctc aaggctgatg ctcctgagta tatcactatt gatattgctc atggtcatgc
    20821 ggatagcgtg atttctatga ttcaacacat caagaaagaa ttgccagata cctttgtcat
    20881 tgctggaaat gtgggaacac cagaagctgt gcgtgaattg gaaaatgctg gtgcagatgc
    20941 tactaaggtc ggaatcggtc ctggtaaggt ttgtatcacc aaggttaaga ctggttttgg
    21001 tacaggtggt tggcagttgg ctgctctacg ctggtgtgcc aaggctgcgc gtaaaccgat
    21061 tatcgctgat ggaggaattc gtactcacgg tgatattgcc aagtctatcc gcttcggtgc
    21121 tagcatgatc atgattggtt ccctctttgc aggacatatt gaaagtccag ggaaaacgat
    21181 tgaagtcgat ggtgaacagt tcaaagaata ttatggttca gcctcacaat atcaaaaagg
    21241 tgcttacaaa aatgtggaag gcaaacgtat cttgcttcct gctaaaggtc atctgcaaga
    21301 cactttaact gagatggaac aagaccttca aagtgctatt tcttatgcag gtggacgtca
    21361 ggttgctgac cttaaacacg ttgattatgt gatcgtgaaa aactccatct ggaatgggga
    21421 tgcttcccac taagacgggg tctttgacca aaaaacttgt tattagagca aatttctgtt
    21481 ataataaaac aagtttccac ccttagtgta atggatatca cgtaagattc cggttcttga
    21541 gatgggggtt cgattccctc agggtggatg taaacattct aaaaagcctt taatagggct
    21601 tttttcttta cactgctcta aatttactgc taaaactgag aatctctgtc taaagaattt
    21661 ccaaatgctt tccagtcccg ttttagagtg actcaggggg ctttttttga tataataaaa
    21721 aggactgtta tcagttagaa agaggttggt atgaaagaat tacaaactgt actaaagaac
    21781 cattttgcaa tcgaatttac agacaaaaag ttactggaaa ctgcctttac tcatacgagt
    21841 tatgccaatg agcaccgcct cttaaaaatt tcacataatg aacgcttgga atttttagga
    21901 gacgctgttc tacagttatt gatttcagaa tatctgtata aaaaatatcc taaaaagcct
    21961 gaaggtgacc tatcaaaact ccgtgctatg attgtccgtg aggagagttt agctggtttt
    22021 gcgcgtgatt gccagtttga ccagtttatc aagttgggta aaggggaaga aaaatctggt
    22081 ggtcgcaatc gtgacaccat tcttggtgat gcctttgaag cctttcttgg tgcccttctt
    22141 ttggataagg atgtggccaa ggtcaaggaa tttatctatc aagtcatgat tcctaaggtt
    22201 gaagcaggcg aatttgagat gattacagac tataaaaccc atctccaaga gttacttcag
    22261 gtcaatggtg atgtggctat tcgttatcag gtgatttctg aaacagggcc tgctcacgat
    22321 aaggtctttg atgtagaagt tcttgttgaa ggtaagagta tcggtcaagg ccaaggtcgt
    22381 tctaagaaat tagcagagca ggaagctgcc aaaaatgccg ttgagaaggg gctggattca
    22441 tgtatttaaa ggaaatcgaa attcaggggt tcaagtcttt tgctgataag accaaggtcg
    22501 tttttgacca aggtgtgacg gcagttgttg gacccaatgg atctggaaag tccaatatta
    22561 cagaaagtct gcgttgggct ttgggggagt ctagtgtcaa gagtctccgt gggggcaaga
    22621 tgccggatgt catctttgct ggaacagaaa gtcgcaaacc gctcaattat gcttctgtag
    22681 ttgtgactct ggataatcat gacggattta tcaaggatgc aggtcaagaa atcagggtgg
    22741 aacgccatat ctatcgtagt ggagatagcg aatacaagat tgacggcaag aaagtccgtc
    22801 tgcgtgatat tcatgacctc ttcttggata ctggattggg acgagattcc ttctctatta
    22861 tttcccaagg gaaggttgag gagattttta attccaagcc tgaggaacga cgagctattt
    22921 ttgaagaagc tgctggagtt ttaaaataca agactcgcag aaaagaaacc gagagtaaac
    22981 tgcagcaaac tcaggataat ctggaccgct tagaggacat tatctacgag ttggataatc
    23041 aaatcaagcc tcttgagaag caagctgaga atgcccgtaa gtttttagac ttggaaggac
    23101 aacgtaaggc tatttattta gacgttctgg ttgctcaaat caaggaaaat aaggctgaac
    23161 tagagtcgac agaagaagag ttggctcagg ttcaagaact cttgatgagt tattaccaaa
    23221 agcgtgaaaa attagaagaa gaaaatcaaa ctcttaaaaa gcaacgccaa gatttacagg
    23281 ctgaaatggc caaagaccaa ggcagtttga tggatttgac cagtctgatt agtgacttag
    23341 agagaaaatt agccctatcg aaactggaat ctgagcaagt agccctcaat caacaggaag
    23401 cacaagcccg tttggctact ttggaggata agagaagttc actcagccaa gaaaaatctg
    23461 ataaagaaag ctctttagcc ctcttggaag aaaatctagt ccaaaataat caaaaactca
    23521 atcgattaga ggctgaattg ctagcttttt cagatgatcc tgatcagatg attgagctct
    23581 tacgtgaacg ctttgtggcc cttttacaag aagaagcaga tgtctcaaac caactgaccc
    23641 gtattgagaa tgagttggaa aatagtcatc agctttctca aaaacaagca gatcaactag
    23701 aaaagctgaa agaacagttg gctacagcta aagagaaggc tggtcagcaa aaggctgagc
    23761 ttgaaactgc caaggagcag gttcagaaat tattggccga ctatcaagtc tgtgctaagg
    23821 agcaagagga gcagaaaact tcctatcaag ctcaacaaag tcaactcttt gaccgtctgg
    23881 atagtctcaa aaacaagcag gctagagcgc aaagtttgga aaatatcctg agaaatcata
    23941 gtaactttta tgcaggtgtt aagagtgttc tccaagagaa agatcgtcta ggtgggatta
    24001 ttggagcagt tagtgagcac ctgacctttg atatgcatta tcaaactgcc ctagaaattg
    24061 cgcttggagc gagtagtcag cacattattg tagaagatga gaatgcggca accaaagcca
    24121 ttgatttact caaacgaaac agatctggtc gtgcaacctt ccttcctttg accactatca
    24181 aggctcgtac gatttctagt cagaaccaag atactattgc tgcaagtcca ggatttctgg
    24241 gcatggcaga tgagctggtt actttcgata ctagactgga agccattttc aagaatttgc
    24301 tagctacaac ggccattttt gataccgtgg agcatgcgcg tgcagcagcg cgccaggttc
    24361 gttatcaggt tcgtatggtg acattggacg gaacagagct gcgcacaggt ggttcttatg
    24421 caggtggagc taatcgccag aataacagta ttttcatcaa gccagaactg gagcaattac
    24481 aaaaagaaat tgctgaagaa gaagcaagtt tgcgttcaga tgaagtgagt ttgaagaact
    24541 tgcaagatga gctagctaga ttgacagaaa gattagaagc catcaaatct cagggagagc
    24601 aggctcgtat tcaggagcaa ggcttgtccc tcgcctatca gcagaccagt cagcaagttg
    24661 aagagctaga aactctttgg aaactccaag aagaggaatt aaatcgtctt tctgagggag
    24721 aatggcaagc ggataaggaa aaatgccaag agcgccttac tacaatcact agtgaaaaga
    24781 ataatctgga agctgagatt gaagagatta agtctaataa aaacgccatc caagaacgtt
    24841 atcaaaactt gcaggaagag ctagctcaag ctcgtctact taagacagaa ctgcaagggc
    24901 aaaaacgtta tgaagttgct gatattgaac gcttaggtaa ggaactagat aatcttgata
    24961 ttgagcaaga agaaattcag cgccttcttc aagaaaaggt tgacaatctt gagaaagttg
    25021 atacggattt gctcagtcaa caggctgatg aagccaaaac tcaaaaaaca aatctccaac
    25081 aaggtttgat tcgcaagcag tttgagttgg atgatattga gggtcaactg gatgatattg
    25141 ctagtcattt ggatcaggct cgccagcaga atgaagagtg gattcgcaag caaactcgtg
    25201 ctgaagccaa gaaagaaaag gttagcgagc gcttgcgcca tctacaaaat caattaacag
    25261 accagtacca gattagctat actgaagcac tagaaaaagc gcatgagttg gaaaatctca
    25321 atctggcaga gcaagaggtg caggatttag agaaggctat tcgctcactg ggacctgtca
    25381 atttagacgc tattgaacag tacgaagaag ttcacaaccg tctggatttc ctaaatagcc
    25441 aacgtgatga tattttgtct gcgaaaaacc tgcttcttga aaccatcaca gagatgaatg
    25501 atgaggtcaa ggaacgcttt aaatcaacct ttgaggccat tcgtgagtcc tttaaagtga
    25561 ccttcaagca gatgtttggt ggaggtcagg cagacttgat attgactgag ggcgaccttt
    25621 taacagctgg tgtggagatt tctgttcaac ctccaggtaa gaaaatccag tcgcttaacc
    25681 tcatgagtgg tggtgaaaaa gctctatcgg ctcttgcctt gcttttctcc attattcgtg
    25741 tcaagaccat tccttttgtc atcttggatg aggtagaggc tgcgctagac gaagccaatg
    25801 ttaaacgttt cggggattat ctcaaccgct ttgataagga cagtcaattt attgtcgtaa
    25861 cccaccgtaa ggggaccatg gcagcggccg attctatcta tggagtgacc atgcaagaat
    25921 cgggtgtttc aaagattgtt tcagttaagt taaaagattt agaaagtatt gaaggatgac
    25981 aattaaacta gtagcaacgg atatggacgg aaccttccta gatgggaatg gacgctttga
    26041 tatggatcgt ctcaagtctc tcttggcttc ctacaaggaa aaagggattt actttgcggt
    26101 ggcttcgggt cggggatttc tgtctctgga aaaattattt gctggtgttc gtgatgacat
    26161 tattttcatc gcggaaaatg gcagtttggt agagtatcaa ggtcaggact tgtatgaagc
    26221 gactatgtct cgtgactttt atctggcaac ttttgaaaag ctgaaaacgt caccttatgt
    26281 agatatcaat aaactgctct tgacgggtaa gaagggttca tatgttctag atacggttga
    26341 tgagacctat ttgaaagtga gtcagcatta taatgaaaat atccaaaaag tagcgagttt
    26401 ggaagatatc acagatgaca ttttcaaatt tacaaccaac ttcacagaag aaacgctgga
    26461 agctggtgaa gcttgggtca atgataatgt ccctggtgtc aaggctatga caactggctt
    26521 tgaatctatt gatattgttc tggactatgt cgataagggt gtagctattg ttgaattagc
    26581 taaaaaactt ggtatcacaa tggatcaggt catggctttt ggagacaatc ttaatgactt
    26641 acatatgatg caggttgtgg gacatcctgt agctcctgaa aatgcacgac ctgaaatttt
    26701 agaattagca aagactgtga ttggtcacca taaggaacgg tcggttatag cttatatgga
    26761 gggcttataa tggcagatat aaaattgatt gcattggact tggacgggac cttgctgact
    26821 actgataaaa ggctgacgga tcgtaccaag gaaaccttga aagctgcgcg tgatcgtggt
    26881 atcaaggtcg tattgacaac tggtcgtccc ttaaaagcca tggatttctt tctccatgag
    26941 ttagggactg acggtcagga agatgagtat accattactt ttaatggtgg attagttcag
    27001 aaaaatacag gagaaatcct tgataaaaca gtcttttcat atgatgatgt ggcacgtttg
    27061 tatgaagaaa cagagaaatt atcactgcct ctcgatgcca tctcagaagg aacagtttat
    27121 caaatccaat cggaccaaga aagtctttat gccaaattca atccagcttt gacctttgtt
    27181 ccagtggact ttgaagactt atctagtcaa atgacctaca acaaatgcgt gactgccttt
    27241 gctcaagaac ccttggatgc agccattcag aagatttctc cagaattgtt tgaccaatat
    27301 gaaatcttta aatcacgtga aatgttgcta gaatggtcac caaagaatgt tcataaagca
    27361 acaggtttgg caaaactaat cagccatctt ggaatcgacc aaagtcaagt gatggcttgt
    27421 ggtgacgagg ccaatgacct ctctatgatt gaatgggcag gtcttggtgt tgctatgcaa
    27481 aacgctgttc ctgaagtaaa ggcagccgca aatgtagtga cgccgatgac caacgatgag
    27541 gaagctgtcg cctgggctat cgaagaatat gtgctaaagg agaactaaga tatgggattg
    27601 tttgaccgtc tattcggaaa aaaagaagaa cctaaaatcg aagaagttgt aaaagaagct
    27661 ctggaaaatc ttgatttgtc tgaagatgtt gatcctacct tcacagaagt tgaggaagtt
    27721 tctcaggaag aagcagaggt tgaaattgtt gaacaagctg tgttccaaga agaggaaatc
    27781 caagacacag ttgaagaaag tctggattta gagccagtta tagaagtttc tcaaaaagaa
    27841 gtcaaagaat ttccacactc agaagaaggg aatactgagt ttctagagac tgtagaagaa
    27901 aataattctg aaattcttga agcagaaagg cctcaaacag aagaaactgt tcaggaaaaa
    27961 tatgaccgca gtcttaagaa aactcgcaca ggtttcggtg cccgcttgaa tgccttcttt
    28021 gctaacttcc gctctgttga cgaagaattt ttcgaggaac tggaagaact gttgattatg
    28081 agtgatgttg gtgtccaagt cgcttctaac ttaacggagg aactacgtta cgaagccaag
    28141 cttgaaaatg ccaagaaacc tgatgcactt cgtcgtgtca tcattgagaa attggttgag
    28201 ctttatgaaa aggatggtag ctacgatgaa agcatccact tccaagataa cttgacagtt
    28261 atgctctttg ttggtgtgaa tggtgttggg aaaacaactt ctatcggaaa actagctcac
    28321 cgctacaaac gagctggtaa gaaggtcatg ctggttgcag cagatacctt ccgtgcgggt
    28381 gcagtagctc agctagctga atggggccga cgagtagatg ttccagtagt aactggacct
    28441 gaaaaagctg atccagccag cgtggtcttt gatggtatgg aacgtgccgt ggctgaaggt
    28501 atcgatattc tcatgattga tactgctggt cgtctgcaaa ataaggataa ccttatggct
    28561 gagttggaaa agattggtcg tattatcaaa cgtgttgtgc cagaagcacc acatgaaacc
    28621 ttcttggcac ttgatgcatc aacaggtcaa aatgccctag tacaggccaa agaattttcg
    28681 aaaatcacac ctttaacggg aattgttttg actaagattg atggaactgc tcgaggaggt
    28741 gtggttctag ccattcgtga agaactcaat attcctgtaa aattgattgg ttttggtgaa
    28801 aaaatcgatg atattggaga gtttaactca gaaaacttca tgaaaggtct cttggaaggt
    28861 ttaatctaat cagaagcaaa aatcctgcaa ggcataaact tgcaggaaat ttttttattc
    28921 taagcgacca tcttgacgat aggcgatatc tggttgccaa gtccatttgg caccgaattt
    28981 ttcaagtagg tcaaagctgg cttgaggtcc catgcttcca gctttatagt catgaagtgg
    29041 ggcaccattt tcatcccaga gctcttcaat acggtcaatc aacttccatg atgcaccaac
    29101 ttcatcccag tggctaaagt tagttgagtt gttatttagg acatcataaa tcaatttctc
    29161 gtatggttct ggagaagcac cagttgcagt cgcatctgta cggtaatcaa gtgagttagg
    29221 agccaagtta aattcttctc ctacttgctt cccatttagg ctaagagaga agccttctgt
    29281 tggttgaata tagatggtca aaatatttgg agcaagtggt tctccaaaga tagaatccat
    29341 ttgtttaaag acgatgttga catgagttcc tttttcagtc agtcgtttac ctgtacggaa
    29401 aaagaaagga acactacgga atcgatcgct gtctacaaag aaggcaccag atgtaaaggt
    29461 ttcagttgtt gattctggat tcacatttgg ctcgctacga taagagatgt atttcatgcc
    29521 atcaatctta ccagagcggt attgcccacg gataaagtgt tctttgagtt cttcatcagt
    29581 tggatgatag aggtttttaa agaccttaat cttttcagca cgaatctcgt cttttgtgaa
    29641 gcttgctggt ttgtccatgg cgaggagcga aagaagttgt agagtgtggt tttggaccat
    29701 gtcacggagg gcaccggatt ggtcatagta gccaccacgt tcttctacac ccaagcgctc
    29761 cgcaaaggta atttgaacat tgtcgataaa atccttgttc caaacgtttt caaaaatcaa
    29821 gtttgcaaag cgaactgcaa agatgctttg gatcatttcc ttaccaagat aatggtcgat
    29881 acggaaaatt tgttcttcgt caaatgttgc taggagttcg tcattcaact tgcttgcagt
    29941 tgcgtaatct gtaccaaatg gtttttcaac gatcaagcgc tcaaaacctt tgccatcgac
    30001 aatgttttca gatttgaggt gtttggcaat ggttccaaag aactgaggtg ccatagacaa
    30061 gaagaagagc ttattgtgtt cagcttggta tttttcatta agctcagctt gtaattgacg
    30121 caaagcaata taatgttccg aatcattgac atcatggctt tgatagtaga agtggctagc
    30181 aaattcttgg gcttgctcgg tactatctgc caaatcaagg atggactcga caactacaga
    30241 ttcaaaatat tccttactcc aaggtctacg ggcagttcca ataacggcaa agtgcttgga
    30301 aagattgccg gatttatata gtctaaaaag ggaagggtag agcttgcgtt tagccaggtc
    30361 tccactcgca ccgaaaattg taacaataac cttagatgac atctagctac ctaatttcta
    30421 tttttattcc tagtcttgct aggtatgagg aaacctcatt tcataaactt aattctaaca
    30481 taattttccg aaaaatcaaa aattccaata cgaagtagaa aaactgcaag gaaatcctta
    30541 cagtttgagt ttagacgttt aagaccttat ctaagaactc tttcagacga gggtgttgtg
    30601 ggttatcaaa gatttggtca ggtgttccgt cttcaaggaa ctcgccatct gcagtaaaga
    30661 taacgcggtt ggcaacctga cgagcaaatc ccatctcatg ggttacgata atcatggtca
    30721 taccttgctc agccaattcc ttcataacgt taagtacgtc tccaaccatc tcagggtcaa
    30781 gggcagaagt tggttcatcg aagagcatga tgtctggatt cattgctagg ccacgagcga
    30841 tggccacacg ttgtttttga ccacctgata ggctatctgg attggcatta gctttatctg
    30901 ctagtccaac cttttcaagc aactccattc ccaattcctc agcttcttcc ttagtcatca
    30961 acttgtgctc aataggagca aaggtgatgt tgtccaatac agacatatga gggaagaggt
    31021 tgaagtgttg gaataccatg ccgatatttt cacggacgtg gtcaacattg gttgtttttt
    31081 cagttaaatc atagccgttc acagtgatgt gaccgctagt gacttcttct aaaagattga
    31141 ggctacggag gaaagttgac ttaccagaac ctgaaggacc gatgatacaa acaacatctc
    31201 cttcatagaa cttagtcgta attcctttta ggacttcatt ttttccatag tgcttgtgta
    31261 aatcatttac atcaattttt aattttgcca ttaacgaatc ctcttttcta agcgtttcgc
    31321 tagtctagtc aaaagtgtga taattacaag atagaagata gcaaggattg catacatctt
    31381 gaaactttgg tagttacgag caatgataat cttaccagtt tggaagagtt caaccaaacc
    31441 gatagcagat acgatagttg tatctttaag agcgataacg aattggttga caaagtttgg
    31501 caacatcaat ttagttgctt gtggcaagat aatcttacgc atggtttttc cataagagat
    31561 acccaagctt cggctggctt ccatttggcc aactggaacg gcctgaatac caccacgaac
    31621 gatttcagcg atataagcag ccgcattgag tgagagggca atggttccag ctacaaagtc
    31681 gttaattggg ctttgttggc ctgtgataga ctcgatgaag tttggaattc cccagaagat
    31741 gaaggctgca agaatcatca atggaatacc acgaataacg tcaacgaaaa tctcagagat
    31801 gacgcgaaga gatttgtatg ggctaacgct aaacataccg aagataattc cgatgacaat
    31861 ggcaatagca aatgagataa gagctagagc aagagtgata ccaagaccgc taaggagttg
    31921 tttgtagttg ttttgaagca agccccagag cgttgtttcg tcaacagtac ttgttgaagc
    31981 agttgaagat tcgctagcta ggtatttgtc aagaatcttt tggaattcac cgtttgcttt
    32041 aaggtttgca agtccgttgt tgaacatttc aatcagttct ggatttgctc cttttttaac
    32101 ggcaaaggct gtttcaccga ttggagttcc agagattgga gttttcaatt tttgaccttg
    32161 gctgatagaa tatttgagaa caggttcatc atccataacg gcatcaatgg caccagtgtt
    32221 taaactgtca tacattgaag aaccatcagc aaaggttttg attttgtaac cgtatttgct
    32281 ttgattttct gttaggaagg tttgagaagc agttccgttt ttaacaccga ctgtctttcc
    32341 ttttagatct tcataagaag caatattgct tgattctttg acaccaagaa tggtattagc
    32401 agtgtagtat gattctgaga agtcaaaagt tgccttacga gcatctgtga cagacatccc
    32461 agcaatgata ccatcggctt gaccagcttg gacagcactg atagcagcat caaaaccagg
    32521 gttggtgatt tcaatttcaa aaccttggtc tttagcgatt gccttaatca attccatatc
    32581 aataccagtg tattggttgc ttgaattttg gaaaacaaaa ggtgcaaaag aagaatcgct
    32641 ggcaatgata tatttagcct taacaggaat agcttttaat cctgcgagag tagttgtagt
    32701 tggcactgct gaagatgatg aagcagtcca tttcttgata attttatcaa gactaccatc
    32761 ttttttcatt tcagccaagg cttggttaaa ttcagtaacc aggtgctcgt atttacttcc
    32821 ttttttcaca ccgaaagcaa aacttcctac agcttcacca tccatttcaa tatggagatc
    32881 ttgaccttgg ttaatggcat attcgataac aggtttgtca tccatcatgg catcgatggc
    32941 accagcactc aagctgttgt tcattaaatc accagtgtca aatgttttaa tagtaaagcc
    33001 gtatttatct ttgattgttt caaggaaacg ttgagcggca gttccgtttt taacaccaac
    33061 ggttttgcca gttaattggt cgtacttgct aattttgtgt gactttgtag tagcaatgac
    33121 aacttttgta tcatagtaag tatcagacat ggtgaagact ttttcacgtt ctttagtctt
    33181 tgtcatccct gccatgatag cgtcggcttg cccagcttga accgcattga ctgctgcgtc
    33241 aaatccagga taggacatct gaatgttcca gcctttaatc tcagcgactt tgttaataat
    33301 gtcaacatca attcctttat aagtttgatc tgaatcttta aactcaaaag gtgcataggc
    33361 ggtatcagaa acaatcttaa tcgtttctgc tttggcaata cctaatgaga aaattgggaa
    33421 taaaattagc aaaaatgcta gaaatttttt cttcattttt agtctccttt tccgaatatt
    33481 ctctcattat atcagaaaaa gtaaaaaaag gcaaattgtt atatttttcg tgtcagaaaa
    33541 tataacattg atttttcctt ttctttcttg aattgctatt aaaaagtgct ataataatag
    33601 tatatataga agaaaagagg acggggatat gaagaacaaa agaatattta aagacttcca
    33661 agcttcaaaa atgaatttaa acatttacac aagccccttg ttagcctttg tttttgtctt
    33721 cataggagag tttgtggctt atactttata tggtattagt ttgttagctc tcatcggact
    33781 tgctagaaat tttggagagg ctggtcaaaa tcttgcaagc tacttgcaga ccttgcatca
    33841 gagcttgacg gataaaacaa gtgactttcg tttaatttta ggattactgg cctttggttt
    33901 tattcttaac actgtgttca gatggacaag aaaagttgag aaaagaccta ttcgaacctt
    33961 gggattttat agagagaatt tcctcagcaa tcttctgaaa ggatttagtc taggcctggc
    34021 actttttctt ctgaccttgt taggtttagt ggtcttaggt caatatcgtt tggaatccat
    34081 tcacttgaat ccttattctc ttgcctttgt cgtctttact atcccatttt ggattttaca
    34141 ggggacagca gaagaagtgg tggcccgtgc ttggctactt cctcaattgg cctcaagaac
    34201 caatctaaaa ctagctattc ttatatctag cctgttcttt accctgcttc atatgggcaa
    34261 ttctggcctc acccctctat ctctagtaaa tctcttttta ttcggagttg ccatggctct
    34321 ttaccttctc aaaactgata cagtttgggg tgttgcaggt attcatggtg cttggaattt
    34381 tgctcagggt aatctctttg ggattttagt tagtggtcaa ccgtcaggaa cgtctctgat
    34441 gaccttttta ccacaaggca atcaagattg gctatcaggt ggttcttttg gcatagaagg
    34501 ttccattatg acaagtctgg tattactact gctgattgtc tatcttgcta ataaattaaa
    34561 gaaagaaaat gaaaggatgt gacttcggtc cgtccttttc ttcgtgaaaa tactataagt
    34621 atgctaaaat aggaatagca catggagaga ggattcttat gatcaatcac attacagata
    34681 atcaatttaa actagtatca aaatatcaac catcaggaga tcaaccccaa gctatcgagc
    34741 agttggtgga taacattgag gggggagaaa aagctcagat tctgatgggg gcgactggaa
    34801 cagggaagac ctatactatg agtcaggtca tttctaaagt caataaacca actctggtta
    34861 ttgcccacaa taaaactctg gctggtcagc tctatgggga gtttaaggaa tttttccctg
    34921 aaaatgcagt tgagtatttc gtatcctact atgattatta ccagccagag gcctatgtcc
    34981 cttctagcga tacctatatt gagaaggata gttctgtcaa tgacgagatt gacaagcttc
    35041 gccactcagc tacctcagcc cttttggagc gtaatgatgt tattgtcgtg gcctcagtct
    35101 cttgtatcta tggtttgggt tcgcccaagg aatacgctga tagtgtcgtt agtctccgtc
    35161 ctggtctaga gatttctcgt gataaactct tgaatgactt ggtcgatatt cagtttgaac
    35221 gtaatgatat tgatttccaa cgcggaagat ttcgtgttcg tggggatgtg gtagagattt
    35281 tcccagcttc ccgagatgaa catgcctttc gagtagaatt ttttggagac gaaattgacc
    35341 gtattcgtga agttgaggct ctgacaggtc aggtgttggg agaagtggat catttagcga
    35401 ttttcccagc gacacacttt gtgaccaatg acgaccacat ggaagttgcc attgcaaaga
    35461 ttcaggccga gttggaggag cagttagctg tctttgaaaa ggaaggtaaa ctgcttgaag
    35521 cccagcgttt gaaacagcgg acagagtatg atatcgaaat gttgcgtgag atgggctata
    35581 ccaatggggt tgaaaattat tctcgccaca tggatggacg gagcgaagga gagcctcctt
    35641 atacgcttct cgacttcttc ccagatgatt tcttgattat gattgacgag agtcatatga
    35701 ccatagggca aatcaagggc atgtacaatg gagaccgttc gcgtaaagaa atgctggtta
    35761 attatggttt ccgtttgccg tctgctttgg acaatcgtcc tctccgtcgg gaggagtttg
    35821 agagtcacgt tcatcagatt gtttacgttt cagcgacacc tggtgactat gaaaatgaac
    35881 agaccgagac agtgattgag caaatcattc gtccaacggg actcttggat ccagaggtgg
    35941 aagtccgtcc gactatggga cagattgatg acctcttggg tgaaatcaat gcccgcgttg
    36001 aaaaaaatga gcgtaccttt atcacaactt tgaccaagaa aatggcagag gacttgaccg
    36061 actacttcaa ggaaatgggt atcaaggtca agtacatgca ctcggatatc aagaccttgg
    36121 aacggacgga gattatccgt gacctgcgct tgggtgtctt tgatgtcttg gtcggaatta
    36181 acctgctccg tgaaggaatt gacgttcctg aagtgagcct cgtagctatt ctcgatgctg
    36241 acaaggaagg tttccttcgc aacgaacgtg gactcatcca gactattgga cgtgctgctc
    36301 gtaacagtga aggccatgtc atcatgtatg cagacacggt tacccagtct atgcaacgtg
    36361 ctatcgatga aactgcccgc cgtcggaaaa ttcagatggc ctataatgaa gagcatggta
    36421 tcgtaccaca gacaatcaag aaagaaatcc gtgacctgat tgccgtgacc aaggcagttg
    36481 ctaaggaaga ggacaaggaa gtcgacatca atagcctcaa caaacaagag cgtaaagaac
    36541 tcgtcaagaa actagaaaaa caaatgcaag aagccgtcga agtgcttgac tttgaactgg
    36601 cggctcagat ccgtgatatg atgttggaag tcaaggcctt ggattagggg aatagtatga
    36661 tttatttaag aaagttaaag agagaagatt tgatgtcttt atgggaaatg gcttattcac
    36721 aacttaatcc agtttggaaa cagtatgatg ctccctatta tgatgattat cagtattttt
    36781 caaattttaa agaattcgaa ctacaaaaat cagaatccat tttaagcaac tcaaatcgcc
    36841 ttggtatttt tgttgatgat aaactagttg ggactgtttc gcgttattgg gtatgtaaac
    36901 aaacaagatg gatggaattg ggaattggta tttatgataa aaaattctgg aacactggta
    36961 ttgggaaagt tgctatgttg cagtggatag ataggacgtt tcaggattac ttggagttgg
    37021 agcatctggg tttgacaact tggtcaggga atcttggtat gatgaaactt gctgaaaaat
    37081 taagaatgaa aaaagaagct catattccaa aagttcgtta ttatcaaggt aaatattttg
    37141 atagtattaa atatggtatt ttgagagaag actgggagaa aataaatgac ggttattatc
    37201 aaatcaatgg aaactcctaa agagatagaa ggtaaatccc ttgttcactg gcaaatgtgg
    37261 agagaggctt atgatgacct tttgcctgca gaatttcagg agacaatgac attagaaaga
    37321 tgtcgactct ttagtcaaaa gtatccagaa aatacattga ttgcgatagg tgatctgaag
    37381 gtagttggtt ttatcagtta tggtaacttt cgtgatgaga ctatgcaagc tggtgaaatt
    37441 attgctttat atgttttaaa agactattat ggaaaaggta tcgcacaaaa gttaatgaaa
    37501 gcagctttga ctgctcttaa tcatttttct gaaattttct tatgggtatt gaaagataac
    37561 aagcgcgcca ttgctttcta tcaaaaaatg ggttttactt ttgatggaca agaaaaaata
    37621 cttgaacttg gaaagcctat aaaggaaaaa cgaatggtgt tctattctaa ataattttaa
    37681 aaaagtaaaa gataatatct ctggtagtaa gtctgaaaat ttaataaatt agaaagcgag
    37741 taaatttatg tcccgttccc aattaacaat tttaacaaat atctgtctga ttgaagacct
    37801 cgaaactcag cgcgtggtga tgcagtatcg cgcccctgaa aacaatcgct ggtctggtta
    37861 tgcctttcct ggaggtcatg tagaaaatga tgaggctttt gcggagtctg tcattcgtga
    37921 aatctacgaa gaaacagggt tgactatcca aaatcctcaa cttgtcggca ttaaaaattg
    37981 gccactagat acaggtgggc gctatattgt catttgttat aaggcgactg agttctctgg
    38041 tacccttcaa tcttcagaag agggagaagt ttcttgggtg caaaaagacc agattccaaa
    38101 cttaaatctg gcctatgata tgctaccatt gatggaaatg atggaagctc ccgacaagtc
    38161 agagtttttc taccctcgcc gtacagaaga cgattgggaa aagaaaatct tctagtcttt
    38221 tactaaataa cctagctgat ccaaggcctc ctcgatatag tggaggtctt gttgtgtttc
    38281 ggcttcgact aggtggtaat ggatgccatc tgtcaattca gatagaggtc taaagtcaga
    38341 atgctcgact tgttctagaa aatgttgcac atctctgcga caagacagtt taagcaaggt
    38401 ttcaatttct ccataaacgg gatggtcaat caaggtattc tggacatgcc caccattatc
    38461 gacaatagca aggagttcct gaccgatttc ttcaacttca tgtttcactt tgaaaagttt
    38521 gtgaacataa ggattggtat caatttgctt atagatgtag ccacgattgg tggataggat
    38581 aggagcgcca tcggctctca aaattgcaat gtcctgcaca atgacctgac gtgtgacatg
    38641 aaaatgttcc gccaaacttt ggccattaag ggctttagga gcttctttca agagttggag
    38701 cagggcttgt ttgcgatctt ttgtcatagc ttttcctttt aacggcgttt tcgaagcact
    38761 ttatagacag ctagtgctaa tgtatagtct accatactat gaataattgt gccaaatcca
    38821 actagtacaa atagaacata gaacatattt tctacattgg tacccgaagt tgcgtaaaaa
    38881 aggacacagg ctaatacttc agcaagggca tgaacaacag ccaaaacaaa attgaaaacc
    38941 caggaagatt ttggtttatc tagggtatcg gggaattttt gtaggtaaag agctcctaaa
    39001 gcaccaaaag atatatggga aaaagcccga aaaacgataa ccatgggata gccagccatc
    39061 aaaaatccaa aactagaggc taggatgaca aaaactgcca tcaagggcga caagaacatg
    39121 gctataaaaa tagcgatgtg gctccccaaa gtataggaag caggtggaat gacaatcttg
    39181 aaaggcataa caattggaat caaaatcgca atagccgtta aaagggctgt cattgtcata
    39241 aattgtgtct ttttccgtgt attcacaaga atctcctttt taactgcata tacactagta
    39301 tggtacaata aaccagacaa taaagcaaga atttacttgg gtttatagat cattttttag
    39361 ttaaaagtta tagtagatgg aaactagaat agtccacctc tacttctaaa acattgttag
    39421 cgatttgact gtcctgatcg atttgtcctg ttcttatttc gttttactat agtaaagatt
    39481 tcattaaaaa gaaactgtat agagcaaaat ctccaccttc aggtttgaaa gcggagattg
    39541 tttttatttt ttcaaggttt gtagtcgtgg aacaatggct agggttagaa ttgcagaaat
    39601 gaccaattca gcaattgaat ttgttgagat aacggttgcc agaagaagtt ggatatttcc
    39661 attataaaca tttccaaata ggaagaagat tcctccaagg acaaagatag tatttgtcaa
    39721 ggaaccaagg gctccagcta aaatcagacc agtcttgttt ttcatcagtt tatagactaa
    39781 gtaaggagtt aaaccaatca aaatacgtgg gacgatggca atgatagctg agtagatgtt
    39841 tccgtttggt acgaagggag agaagaggta gcttgtcggt agaatcgtaa tcgtgttaac
    39901 cgtcaagcta agtaatccca tcaaaaatcc aagtgtaacc ccaactcgtg gaccataaat
    39961 aatgctggca ataatgacag gaatatgaac aatggtcggt ttgattggaa atggaaaaag
    40021 gttaaagata agtgagctca gaaagtgtat cacgagcatg gtagcaaaaa agatagcaat
    40081 gggtgcaata ttagagcgtt ttttcatcga tagtttcctt tattctttct aaaataattg
    40141 tgaggtcagc taaagctcct cgtccgtggt ctccacaagc tagtagggat tccttaggag
    40201 caatcagctg atagccgtag gtttctaatg ttttcagatt attctgagtt actggatggt
    40261 catacatttt tgtattcata gcaggagcta ttagtttggg aatatgactt ggtagggcta
    40321 gagctgtact ggttaccatg ttgtccgcaa atccgtgagc tagttttgca atagtgttag
    40381 cagttgcagg taccacgata aataaatctg ctttttttcc aagttcgata tgattgacct
    40441 gatcaggata gggttccttc atgacatcca agtggacagg attctgtgag agtacctgta
    40501 gtgtcaaagg ttggataaac tctgtagcag cctgagtcat taagacagtg acttgatggc
    40561 cttgtttttt tagagaactg actaaatctg ccgacttata agaggcgatt gaacccgtta
    40621 cagccaagag aatgtttgcc atagttttcc tttctaagaa tgataggctt gaattttttc
    40681 aaggaggagt tctgcaattt cttctttagt ctggactgtt tgaagctgat ttttctcaac
    40741 aaatatagct cggtgctgat ctgctgaaat ttgagtcagg tcattcgcga tgattaaatc
    40801 tgcttgattc ttgataagac tttttcgtgc aatgtcaacc agatgatctt cggtaacatc
    40861 aaccagcagt ttgaaaccaa tcagatgaat agtgggattc cattccttga ctagggatat
    40921 gattttgggt gtctttttaa ggaacaaaac ctgaacctca tcagttgaag aaatcttggc
    40981 ctgatgattc tgcttgctta aaaattcttt tagattggag ctagcctgaa cttcctcaag
    41041 ccctgtcata taaacaggag tgtagtcaga aacagccatt gagtggatca agacctgata
    41101 atcctgaaca cgttcttgca tttctattag aaggtccttg gtattggtaa tttctcgaat
    41161 acttaggtta ggatgaggct ctggcttcag agctcgtttt gtcgtaatta aacaaacttc
    41221 atgccctgca gaaagcaaag tctctgtgat aattttcccc aagtgacctg tagaatggtt
    41281 agtgatagag cggacgctat cgatagcttc actggtaccg cccgatgtaa ctaaaatttt
    41341 catagcacta ttgtacacaa aaataagcgg taagtaaaat gaaagtgata aatttttggt
    41401 aaaaacgaag atttactata gtttcaaact ataaagccat ataaaattta agaaaggact
    41461 ctaaaagcct taaaaacaga gatatttacg aacgtttaga gagttttagg atgttaaaaa
    41521 tcttgttttg tgatataatg aattatcata taagaggtta gaggaatttt gaatgaaaac
    41581 agatattgaa atcgcacaga gtattgagtt gaagccaatt gttgatgttg tagagaaact
    41641 tggtatttct tatgacgatt tggagttgta cggaaagtac aaggctaaac tcagctttga
    41701 taaaattcgt gcagttgaga gcaatccagt cggtaaattg atcttggtta ctgccatcaa
    41761 cccaacacct gcaggtgaag gaaagtcgac gcttaccatt ggtcttgcgg atgccttgaa
    41821 caagattggc aagaaaacca tgattgctat ccgcgaaccg tctcttggtc cagtcatggg
    41881 gatcaagggt ggtgctgctg gtggtgggta tgcacaagtt ctgccaatgg aagacatcaa
    41941 cctccacttt actggagata tgcatgctat tacaactgcc aacaatgccc tttctgcctt
    42001 gattgacaac cacttgcacc aagggaatga gctggaaatt gatcaacgtc gtatcctctg
    42061 ggaacgcgtt gtggacttga acgaccgtgc gctccgccat gtgactgttg gtcttggtgg
    42121 tcctctaaac ggtattccac gtgaggatgg ttttgatatt acagttgctt cagaaatcat
    42181 ggcaattctt tgcttggcaa cggacatcga ggacttgaaa cgtcgtttgg cgaatatcgt
    42241 tattggttat cgctatgacc gtacgcctgt ttctgtaggt gatttgcagg ttgagggtgc
    42301 cttggctttg attttgaagg atgctattaa gccaaacttg gttcagacaa tttacggtac
    42361 acctgccttt gtacacggtg gtccatttgc caatatcgct catggctgta actctgtttt
    42421 ggcgacgaca acagcccttc acttggctga ttacactgtt actgaagctg gttttggtgc
    42481 ggaccttggt gctgagaaat tccttgatat caagacacca aacttgccaa catctccaga
    42541 tgcagttgtc attgtcgcaa cccttcgtgc ccttaagatg aatggtggtg tggctaaaga
    42601 cgctctgact gaagaaaatg tagaggcagt tcgtgcaggt tttgctaact tgaaacgcca
    42661 cgttgaaaat atccgtaagt tcggtattcc agcagttgta gctattaacg aatttgtatc
    42721 tgatacagaa gctgaaattg cagtcttaaa agaactctgt gcctcaatcg atgtaccagt
    42781 tgaattggct agtgtctggg ctgatggagc agaaggtgga gtagcacttg ccgaaacagt
    42841 tgttaagaca attgctgaaa atccagctaa ctataaacgt ttgtacgata atgccctttc
    42901 tgtccaagaa aagattgaaa aaattgtcac tgaaatctat cgtggtagca aagtgaactt
    42961 tgagaagaaa gctcaaacac aaattgctca aatcgttcaa aacggttggg acaaattgcc
    43021 aatctgtatg gctaaaactc aatacagttt ctcagacaat ccaaatgcgc ttggagcacc
    43081 agaaaacttt gaaattacca ttcgtgaatt ggtaccaaaa ttaggtgcag gcttcatcgt
    43141 tgccttaact ggtgatgtta tgaccatgcc aggtcttcca aaacgtccag cagctctcaa
    43201 catggatgtt gaaagcgatg gaactgtact aggcttgttc tagtggattg aaattgactt
    43261 taagtgagtt tggaaataat atccaagctc attttttctc agactgcaag cagttcatca
    43321 ataagattta tactcttcga aaatctcttc aaactacgtc agcttcacct tgccgtaggt
    43381 atatgatact gactctgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg
    43441 cggctagctt cctagtttgc tctttgattt tcattgagta taagtagata gaaaagttat
    43501 atactatcta ttgaaaatat tataaatcag atacaaagac aggtgaaacc ttctgtgtta
    43561 tactagagat atgttagatt tgaaagaata cggtatcgtc atgtggccgg aggagaaagt
    43621 catttctttc cgtgagaaac ttctcgcttg gtatgatgaa aacaaaagag atttgccttg
    43681 gaggagaagt aaaaatcctt atcacatctg ggtatctgaa atcatgcttc agcagaccag
    43741 ggtggataca gttatccctt actacgaaag attcctggac tggtttccaa ctgtcgaaag
    43801 tctggcaact gcgcctgagg agagtttact gaaagcttgg gagggcttgg gctattattc
    43861 tcgagttcgc aatatgcagg ctgcagccca gcagattatg actgactttg gtggccaatt
    43921 tccaaatacc tatgaaggaa tttccagctt gaaagggatt ggaccttaca cagcaggagc
    43981 catttccagt attgctttta acttgcctga gccagctgta gatggtaatg tcatgcgggt
    44041 cttggcgcgt ctgtttgaag tcaaccacga tattgggatt ccaagtaatc gaaaaatttt
    44101 tcaggcaatg atggagatct tgattaatcc ggatcgtccg ggtgatttta atcaagcctt
    44161 gatggactta gggtctgata ttgagtctcc tgtaaatccc agacctgaag aaagcccagt
    44221 caaggacttt agtgcggcat atcagaatgg aaccatggac cgttatccaa ttaaatctcc
    44281 taagaaaaag ccggttccta tttatcttaa agccttagtt gtgaaaaatt ctcaaggaca
    44341 atttttactt gaaaaaaatg aaagcgaaaa gctcttggca ggtttttggc atttcccctt
    44401 tatagaagtt gataactttt cgcaagaaga gcagtttgac ctctttcatc aggttgcgga
    44461 agaaagtgtg aactttggcc ccagtccaga agagagtttc cagcaggact atgacctaga
    44521 tgttgattgg cttgatgttt gttttgatac agtccagcat gtttttagtc atcgaaaatg
    44581 gcatgtacag attgtagcag gtcaggtgag tgacttccat gatttttcag atagggaagt
    44641 tcgttggctt tcaccagaag aattcaagaa ttacccactt gccaaacccc aacaaaaaat
    44701 ctggcaggct tatgcacaag ccaacttaga cagtagccaa gactagctat tgtgtcttct
    44761 gactattttt tggtataata gtagagaaaa aggtgaacat atgaaaaaaa tactaattgt
    44821 agatgatgag aaaccaatct cggatattat caagtttaat atgaccaagg aaggttacga
    44881 agttgtaact gcttttaatg gtcgtgaagc gctagagcaa tttgaagcag agcaaccaga
    44941 tattattatt ctggatttga tgcttccaga aattgatggt ttagaagttg ctaagaccat
    45001 tcgtaagaca agcagtgtgc ccattcttat gctttcagcc aaagatagtg aatttgataa
    45061 ggttatcggt ttggaacttg gggcagatga ctatgtaacg aaacccttct ccaatcgtga
    45121 gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa cctatgccag tagatggtca
    45181 ggaagcagat agtaaacctc aacctatcca aattggggat ttagaaattg ttccagacgc
    45241 ctacgtggct aaaaaatatg gcgaagaact agacttaacc catcgtgaat ttgagctttt
    45301 gtatcattta gcatcgcata caggtcaagt catcacgcgc gaacacttgc ttgagactgt
    45361 ctggggttat gactattttg gtgatgtccg tacagttgat gtgactgtac gacgtctgcg
    45421 tgagaagatt gaagatacgc ccagccgacc agagtatatc ttgacgcgcc gtggtgtagg
    45481 gtattacatg agaaataatg cttgatttac tgaaacaaac catttttacc agagatttta
    45541 tctttatcct gattttgtta ggtttcatcc ttgttgtgac cctcttatta ctggaaaata
    45601 gacgtgataa tattcagttg aagcaaatca atcaaaaggt taaagatttg attgcaggag
    45661 attattccaa ggttcttgat atgcaaggtg ggtctgaaat caccaatatt accaataatt
    45721 tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa tctagaacaa gagagtaaga
    45781 ggctaaatag tattctgttt tatatgacag atggggttct tgcgaccaac cgtcggggtc
    45841 agattatcat gattaacgat acagccaaga agcaactggg gttggttaag gaagatgttc
    45901 tgaatagaag cattttggaa ttgctcaaga tagaagaaaa ctatgaattg cgtgatttga
    45961 ttacccaaag tccagaattg ttgctagatt cccaagatat caatggcgaa tatttgaacc
    46021 ttcgagttcg ctttgccttg atacgtcgag agtctggctt tatttcaggt ttggtggctg
    46081 ttttgcatga tacgacggag caggagaagg aagaacgcga acgaagactc tttgtttcca
    46141 atgttagcca tgagttacgg actcctctga ctagcgtaaa atcctatctt gaagccttgg
    46201 atgagggggc tttgtgtgaa actgtagcac cagactttat caaggtttct cttgatgaga
    46261 ccaaccgtat gatgcgcatg gtgacggatc tcctccatct ttcacgtatt gataatgcta
    46321 ccagtcacct agatgtggaa ctgattaact tcactgcttt tattaccttt atcctcaatc
    46381 gttttgacaa gatgaaagga caggaaaagg agaaaaaata tgagttggtg agagattatc
    46441 ccatcaattc tatctggatg gaaattgata cagataagat gacgcaggtt gtcgacaata
    46501 ttttaaataa tgctattaag tattcgccag atgggggtaa aatcactgtc agaatgaaga
    46561 caactgaaga ccagatgatt ttatccattt ctgaccacgg tttggggatt cctaagcagg
    46621 atttaccacg tatctttgac cgtttctatc gtgtggatcg tgctagaagt cgtgcacaag
    46681 gtggtacagg tctaggactg tctatcgcta aagaaattat caaacaacat aagggcttta
    46741 tttgggccaa gagtgaatac ggcaagggtt caacctttac cattgtgctc ccttatgata
    46801 aggatgcagt gaaagaagaa gtatgggagg atgaagtaga agactagaat gagtgaaata
    46861 ggctttaaat acagtatttt agcgtcgggt tccagtggaa attcttttta tctggaaacc
    46921 tcaaaaaaga agcttttagt agatgcaggc ttgtctggca agaaaattac cagtctgcta
    46981 gctgaaatta accgtaagcc agaagacctg gatgccatct tgattaccca tgagcattca
    47041 gatcatatcc atggagtagg cgttttggct cgcaagtatg gtatggatct ttatgccaat
    47101 gaaaagacct ggcaagctat ggaaaatagt aaatatcttg gcaaggtgga ttcttcgcaa
    47161 aagcatattt ttgaaatggg taaaaccaaa acctttggag atatcgacat cgagagtttt
    47221 ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct ttatgaagga tgataagagt
    47281 tttgtccttt tgacagatac aggttatgtc agtgaccgta tggcgggcat tgtcgaaaat
    47341 gcggatggct atcttatcga ggccaaccat gatgtagaga ttttgcgatc aggttcttac
    47401 gcttggcgac tcaaacaacg aatcctatct gaccttggtc acctttctaa cgaggacggt
    47461 gctgaagcta tgattcggac gctaggaaat cgtactaaga agatttacct tgggcattta
    47521 tctaaggaaa ataatatcaa ggaactggct catatgacca tggtcaatca gctggctcaa
    47581 gctgatctgg gagtcggagt agactttaag gtttatgata cctcaccaga taccgcaaca
    47641 ccattgacag agatatagaa agaacgctga gaaggtgttc tttttatatt gactgaacac
    47701 ctaaaaagta atacaatggt gttaccatta aaaaagggag cacaaaagat gactactatt
    47761 acattaaaag tttctgaagc tgataaaaca tttatgaaag caatggctaa gtttgaagga
    47821 gtttcccttt cggaacttat tcgcaccaaa actcttgaag ccctagaaga tgaatacgat
    47881 gctcgtgtgg cagatttagc ctatcaagag tatttagaag acttggaaaa aggagttgaa
    47941 cccattactt gggaagaaat gatgcatgat ttaggcttga aggatgaata atttgtataa
    48001 attagttcca acaagacgtt ttatcaagca attgaaaaaa ttggaccgtt atacgcagaa
    48061 gctaattaca aactatttac aaaccaatgt tttggaaggt ccaagacgac acggaaaggc
    48121 tttggttggt aatcgcgttg gtcaatggcg ctatagaatt ggtaattatc gagttatcgt
    48181 acaaattgta gatgatgaat tagtcgttgc tactctagaa gttggtcatc ggagagatat
    48241 ttattgaatt aaagctgagt aataacaata tagaaagtaa ggagagtaaa aatttgaaga
    48301 aaaaatggtt atttgcagat tattatgata caacaattat tttacttgct ttaatctctg
    48361 ttattctggt attacttgga tttgctgaga tgactgattt ggacaatccg ccttatagta
    48421 ttattgattt agtaatctgg ggtgtttttg taattgatta tagttggcgc ttttttatta
    48481 ctaaaagaaa atggcgcttt attcttgaaa atatttttga tttattgacc attctccctt
    48541 taaatgctat ttttacagtg tttcgattag gacgtatctt ccgcttagca aggctgacaa
    48601 aattactgaa actgactcgt ttacttagaa taattggact tacaggtaaa ctagaaagaa
    48661 aaattagtag attcttacga acaaatggat tgatttatat cttgtatgtt aatatcttta
    48721 ttgttctagt agggagttcg attttatccg ttgttgaaga aaaatccttc tcagatagtc
    48781 tttggtgggc tcttgtgaca gtaactactg ttggttatgg tgatattgtt ccagtttccc
    48841 tttttgggaa atggctagca gttttactga tgcttgtcgg tattggaaca atagggatgc
    48901 taacaagtgc tttgacgaac ttttttgtaa aggataatcc agatgaacag ataaaacttg
    48961 ataaactcaa agacgaatta tcgagctaaa gaatattaat agagaaacaa tctgaaaaaa
    49021 tcgaagaact acattgaatg ataaaagact tagttgaaaa aatatcataa aggtgagaca
    49081 aaataaaact tgattcgagg agaaatcaag taagttttga cacaatagaa cgcatattat
    49141 caggtataaa aacttgatac tatgcgtttt atagagaaat aaaataaaat ctgaacaaat
    49201 caattaggaa tttaaagcat tttataacaa cgttttagag taatggggtg ctatttcaac
    49261 ttcaacctac tataatacag aaaaaaatac agaaaaaaac aactccctga tgattcaagg
    49321 agttgtctat agttaaatta gtttttagaa gcttcttgga attctggatt tttccatgct
    49381 tcgtcaataa tagcttgcaa ttctttagca gatgcttgca ttttttgagt ttctgcatcg
    49441 ttcaatggaa tgtttactgg acgaacgata ccatgtgcac caacaacagc tggttgaccg
    49501 ataaagacat tctcaactcc gtattgacct tcttggaata ctgaaagtgg aagtactgcg
    49561 ttttcatcgt caaggattgc tttagtgata cgagcaaggg ctactgcgat accgtagtat
    49621 gttgcacctt ttttgttgat gattgtgtag gctgcatcac gaacaccttc gaacaattca
    49681 atcaattcag cttcttgaac attttgagtg tctttaagga attcttcaag gtttacacca
    49741 gcgatgttag cgtgtgacca aacagcgaac tcagagtcac cgtgttcacc catgatgtag
    49801 gcgtgcactg aacgagcatc cacatccaat ttttcagcaa gtgcttgacg gaaacgagct
    49861 gagtcaagtg aagtacctga accgataacg cgttctttag ggaaaccaga gaatttccaa
    49921 gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa ggaagatacc tttgaaacca
    49981 gattcaacaa cttgagttac gattgatttg ttgatagcaa ggtttttacc tacaaggtca
    50041 agacgagttt cacctggttt ttgaggtgca cctgcagtga tcacaacaag gtcagcgtct
    50101 gcacagtcag agtattgagc tgcatagatt tttttaggtg aagtgaaggc aagggcgtga
    50161 ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt gtggaatttc gataattcca
    50221 agctcttgtg caattccttg gttaacaagt gcaaaagcgt aagatgaacc tacagcacca
    50281 tcaccgacaa ggataacttt tttgtgttgt ttagttgaag tcattgtttt aaacatctcc
    50341 ttaattttat taggggattt tccctagaca acttcattct atcactttta aaaaactttg
    50401 tcacgaatat gccttatagt tctcgatgta aacgttttag tggtttagag gctgaaatag
    50461 atgggaattt atggtataat gttgttactt actaattgtg aaatgaggca tttattaatg
    50521 caggataaaa atttagtgaa tgtcaatctg acaaaggaga tgaaggcaag ttttatcgac
    50581 tacgccatga gtgttatcgt agcgcgagct cttcctgatg ttcgagatgg cttaaaacct
    50641 gttcaccgtc gcattctcta cggaatgaat gaattgggtg tgaccccaga caaaccccat
    50701 aaaaaatctg ctcgtattac aggggatgtc atgggtaaat atcacccaca cggggattcc
    50761 tctatttatg aagccatggt ccgtatggct caatggtgga gctaccgtta catgcttgta
    50821 gatggtcatg ggaattttgg ttccatggat ggagatagtg ctgccgctca acgttatacc
    50881 gaggcacgta tgagcaagat tgctctggaa atgcttcgtg atatcaacaa aaatacagtt
    50941 gatttcgttg ataactatga tgccaatgaa cgggaaccct tggtcttgcc agcgcgtttt
    51001 ccaaaccttt tggttaatgg agcaactggt atcgcggttg ggatggcaac caatattcca
    51061 cctcataatc tgggtgaaac cattgatgca gtgaagttgg tcatggataa tcctgaagtg
    51121 actaccaagg acttgatgga agtcttgcct ggaccagatt ttccaactgg tgctcttgtc
    51181 atggggaaat caggtatcca taaggcttat gaaacaggta aaggttcgat tgtcctacgt
    51241 tctcgtacag agattgaaac gactaagact ggtcgtgagc gtatcgttgt aacagaattt
    51301 ccttacatgg tcaataaaac caaggtgcat gagcatattg ttcgcttggt tcaggaaaaa
    51361 cgcattgagg gtatcacagc agtacgtgat gagtcaaacc gtgaaggtgt tcgatttgtt
    51421 attgaagtca agcgcgacgc ctcagccaat gttattctca ataacctctt caaaatgacc
    51481 caaatgcaaa ccaattttgg attcaatatg ctcgctatcc aaaatggtat accgaaaatt
    51541 ttgtctcttc gtcagatttt ggatgcttat attgagcacc aaaaagaagt ggttgttcgt
    51601 cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc atatcttaga aggtctcttg
    51661 attgcgctag accatatcga cgaagtgatt cgtatcatcc gtgctagtga aacggatgcg
    51721 gaagctcaag ctgagttgat gagcaagttt aagctttctg aacgtcaaag tcaagctatc
    51781 cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg ataagattca atctgagtat
    51841 gatgacctct tggctctgat tgcggattta gcagatattc ttgctaagcc tgaacgtgtt
    51901 tctcaaatta tcaaagacga attggatgaa gttaaacgta aattttctga taaacgccgt
    51961 acagagttga tggttggaca gatcttgagt ctcgaggatg aggacttgat tgaagaatcg
    52021 gatgtcttga ttaccctttc taacagaggc tacattaagc gtttggatca ggacgagttc
    52081 actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg gagtgaaaga tgatgacttt
    52141 gttcgtgagt tagtgtcaac tagcacccat gatcatctgc tcttcttcac aaacaaggga
    52201 cgtgtctatc gtcttaaagg ttatgaaatt cctgagtatg gtcggactgc caaagggcta
    52261 ccagtagtca atctcttgaa attggatgaa gatgaaagta ttcagacggt tatcaatgtt
    52321 gagtctgatc gcagtgatga tgcttatctc ttctttacaa cccgtcacgg tattgtgaag
    52381 agaactagtg ttaaggagtt tgccaatatt cgtcaaaatg gtctcaaagc gctgaattta
    52441 aaggatgaag atgagttaat caatgtcttg ttgacagaag gagatatgga tattatcatt
    52501 ggtaccaagt ttggttatgc agttcgcttt aatcaatcag ccgttcgtgg tatgagccgt
    52561 atcgccactg gtgtgaaagg tgttaacctt cgtgaaggag acacagttgt tggtgccagc
    52621 ttgattactg atcaagatga ggttcttatt atcacagaaa aaggatatgg taagcgtaca
    52681 gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg gaatgcagac agctaaaatt
    52741 accgaaaaaa atggcttgct ggccggtctt atgactgttc aaggggatga ggatttgatg
    52801 attatcactg atacaggtgt catgattcga accaatcttg ccaatatttc acaaacagga
    52861 cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag atgctcagat agtgactttc
    52921 acaacggttg cggtggcaga aaaagaagaa gttgggacag aaaacgaaac agaaggtgaa
    52981 gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg aaaaaatctg ctgacaaata
    53041 tcctagcagg atttctgata ttactgtcac tggctttgat ttttaatact caaattcgaa
    53101 atattttcat agtctggaat accaataagt atcaagttag ccaggtatca aaagaaaaat
    53161 tagaagaaaa tcaggataca gaaggcaatt ttgactttga ttctgtcaaa gctatctctt
    53221 cggaagctgt tctaacttct caatgggatg ctcaaaaatt accagttatt gggggaattg
    53281 caattcctga attggaaatg aatttgccga tttttaaagg acttgataat gttaatctct
    53341 tctacggagc tggtacaatg aaacgcgagc aagtaatggg agaaggaaat tatagtctag
    53401 ctagtcacca tatctttggt gttgataatg ctaataaaat gttattttct cctttagata
    53461 atgctaaaaa tggcatgaag atttatctaa ccgataaaaa taaagtttat acttatgaaa
    53521 tacgtgaagt caaacgtgtg acaccggatc gtgttgatga agttgatgat agagatgggg
    53581 tcaatgaaat cacattagta acctgtgaag accttgctgc tacagaacgt attattgtca
    53641 aaggtgattt gaaagaaaca aaagattatt cacaaacatc tgatgaaatt ctaacagctt
    53701 tcaatcaacc atataaacaa ttttattaat acaaatcagt gaaatcatgg atttcactga
    53761 ttttttaaga ttttcataaa aatatagtaa aatgaaataa gaata
//
LOCUS       DAVMBH010000009        46772 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVMBH010000009 DAVMBH010000000
VERSION     DAVMBH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.009"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(1..297)
                     /locus_tag="VYP30_000629"
     CDS             complement(1..297)
                     /locus_tag="VYP30_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807666.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VYP30_000630"
     CDS             complement(281..2440)
                     /gene="pfbA"
                     /locus_tag="VYP30_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1807667.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3570..4796)
                     /locus_tag="VYP30_000631"
     CDS             complement(3570..4796)
                     /locus_tag="VYP30_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1807668.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4839..5531)
                     /locus_tag="VYP30_000632"
     CDS             complement(4839..5531)
                     /locus_tag="VYP30_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1807669.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5704..7455)
                     /locus_tag="VYP30_000633"
     CDS             complement(5704..7455)
                     /locus_tag="VYP30_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807670.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7445..9190)
                     /locus_tag="VYP30_000634"
     CDS             complement(7445..9190)
                     /locus_tag="VYP30_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1807671.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLFLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9396..9692)
                     /locus_tag="VYP30_000635"
     CDS             complement(9396..9692)
                     /locus_tag="VYP30_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1807672.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     SVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9711..9848)
                     /locus_tag="VYP30_000636"
     CDS             complement(9711..9848)
                     /locus_tag="VYP30_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807673.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNIA
                     P"
     gene            complement(9845..10300)
                     /locus_tag="VYP30_000637"
                     /pseudo
     CDS             complement(9845..10300)
                     /locus_tag="VYP30_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10434..11261
                     /gene="xth"
                     /locus_tag="VYP30_000638"
     CDS             10434..11261
                     /gene="xth"
                     /locus_tag="VYP30_000638"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1807674.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAKLDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11273..11416
                     /locus_tag="VYP30_000639"
     CDS             11273..11416
                     /locus_tag="VYP30_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1807675.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11527..11655
                     /locus_tag="VYP30_000640"
     CDS             11527..11655
                     /locus_tag="VYP30_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1807676.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHEFAVLDPNGYFLRFSE"
     regulatory      12038..12133
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12533..13114
                     /locus_tag="VYP30_000641"
     CDS             12533..13114
                     /locus_tag="VYP30_000641"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1807677.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13114..14376
                     /locus_tag="VYP30_000642"
     CDS             13114..14376
                     /locus_tag="VYP30_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1807678.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14427..14888)
                     /locus_tag="VYP30_000643"
     CDS             complement(14427..14888)
                     /locus_tag="VYP30_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV1807679.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14885..15649)
                     /locus_tag="VYP30_000644"
     CDS             complement(14885..15649)
                     /locus_tag="VYP30_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HEV1807680.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15830..16234)
                     /locus_tag="VYP30_000645"
     CDS             complement(15830..16234)
                     /locus_tag="VYP30_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1807681.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16304..17785)
                     /locus_tag="VYP30_000646"
     CDS             complement(16304..17785)
                     /locus_tag="VYP30_000646"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1807682.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(17804..18982)
                     /locus_tag="VYP30_000647"
     CDS             complement(17804..18982)
                     /locus_tag="VYP30_000647"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1807683.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKREDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19146..20153
                     /gene="galR"
                     /locus_tag="VYP30_000648"
     CDS             19146..20153
                     /gene="galR"
                     /locus_tag="VYP30_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1807684.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLNQ
                     E"
     gene            complement(20200..21237)
                     /locus_tag="VYP30_000649"
     CDS             complement(20200..21237)
                     /locus_tag="VYP30_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1807685.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRSCVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21238..21591)
                     /locus_tag="VYP30_000650"
     CDS             complement(21238..21591)
                     /locus_tag="VYP30_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1807686.1"
                     /translation="MNIKSASDLLGISADTIRYYERIGLVPPITRTATGIRDFQVQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21835..22725)
                     /locus_tag="VYP30_000651"
     CDS             complement(21835..22725)
                     /locus_tag="VYP30_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1807687.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVIAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLNNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22858..23394
                     /locus_tag="VYP30_000652"
     CDS             22858..23394
                     /locus_tag="VYP30_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1807688.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTENYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23561..24367)
                     /locus_tag="VYP30_000653"
     CDS             complement(23561..24367)
                     /locus_tag="VYP30_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1807689.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24712..26232)
                     /locus_tag="VYP30_000654"
     CDS             complement(24712..26232)
                     /locus_tag="VYP30_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1807690.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26225..26953)
                     /locus_tag="VYP30_000655"
     CDS             complement(26225..26953)
                     /locus_tag="VYP30_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807691.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQALTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            complement(26968..27732)
                     /locus_tag="VYP30_000656"
     CDS             complement(26968..27732)
                     /locus_tag="VYP30_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1807692.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27736..28179)
                     /locus_tag="VYP30_000657"
     CDS             complement(27736..28179)
                     /locus_tag="VYP30_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1807693.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28861..29157)
                     /locus_tag="VYP30_000658"
     CDS             complement(28861..29157)
                     /locus_tag="VYP30_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1807694.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKIL"
     gene            complement(29179..30243)
                     /gene="pepA"
                     /locus_tag="VYP30_000659"
     CDS             complement(29179..30243)
                     /gene="pepA"
                     /locus_tag="VYP30_000659"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1807695.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPEMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30644..31345
                     /gene="galE"
                     /locus_tag="VYP30_000660"
     CDS             30644..31345
                     /gene="galE"
                     /locus_tag="VYP30_000660"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1807696.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVG
                     SRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTVSLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31768..32727
                     /locus_tag="VYP30_000661"
     CDS             31768..32727
                     /locus_tag="VYP30_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807697.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32717..33673
                     /locus_tag="VYP30_000662"
     CDS             32717..33673
                     /locus_tag="VYP30_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1807698.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            33670..34422
                     /locus_tag="VYP30_000663"
     CDS             33670..34422
                     /locus_tag="VYP30_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1807699.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34518..35483
                     /locus_tag="VYP30_000664"
     CDS             34518..35483
                     /locus_tag="VYP30_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1807700.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35708..35950)
                     /gene="yidD"
                     /locus_tag="VYP30_000665"
     CDS             complement(35708..35950)
                     /gene="yidD"
                     /locus_tag="VYP30_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1807701.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFDLTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35950..36672)
                     /locus_tag="VYP30_000666"
     CDS             complement(35950..36672)
                     /locus_tag="VYP30_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1807702.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36659..37228)
                     /locus_tag="VYP30_000667"
     CDS             complement(36659..37228)
                     /locus_tag="VYP30_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1807703.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37247..37975)
                     /locus_tag="VYP30_000668"
     CDS             complement(37247..37975)
                     /locus_tag="VYP30_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1807704.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37975..38715)
                     /gene="xerD"
                     /locus_tag="VYP30_000669"
     CDS             complement(37975..38715)
                     /gene="xerD"
                     /locus_tag="VYP30_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1807705.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISVQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38706..39167)
                     /locus_tag="VYP30_000670"
     CDS             complement(38706..39167)
                     /locus_tag="VYP30_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1807706.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39164..39685)
                     /locus_tag="VYP30_000671"
     CDS             complement(39164..39685)
                     /locus_tag="VYP30_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1807707.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39661..40632)
                     /locus_tag="VYP30_000672"
     CDS             complement(39661..40632)
                     /locus_tag="VYP30_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1807708.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40629..41423)
                     /gene="racE"
                     /locus_tag="VYP30_000673"
     CDS             complement(40629..41423)
                     /gene="racE"
                     /locus_tag="VYP30_000673"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1807709.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41630..41878)
                     /locus_tag="VYP30_000674"
     CDS             complement(41630..41878)
                     /locus_tag="VYP30_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1807710.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42020..43645)
                     /gene="treC"
                     /locus_tag="VYP30_000675"
     CDS             complement(42020..43645)
                     /gene="treC"
                     /locus_tag="VYP30_000675"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1807711.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43823..45790)
                     /gene="treP"
                     /locus_tag="VYP30_000676"
     CDS             complement(43823..45790)
                     /gene="treP"
                     /locus_tag="VYP30_000676"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1807712.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            45975..46685
                     /gene="treR"
                     /locus_tag="VYP30_000677"
     CDS             45975..46685
                     /gene="treR"
                     /locus_tag="VYP30_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1807713.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13687 a        10643 c         8747 g        13695 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctcc gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttacca ccgaatatac
      841 tattctctga cactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc ggcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc tactgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aaccattagt ggttgaatta gaggcaatca tttcagcaga acgattctga ttaacagttg
     2221 gtgaattatc taaatcatta gtaattgcat tagaagactc ttttgtagcc atcggtgaag
     2281 aactagtaac aacttcatcc gataaaatac cttggcttcc caaaattgaa attgccaata
     2341 gtaccgagca agtccccacc tttaatttac gaatactgaa tacctcatta ggaacaaaat
     2401 atttcatcag aacctccaat ttttttacta tttttaacaa ttgattatta cttttcttaa
     2461 aatagataga atgacaccgc tgtcattatc tttatcatat attttccaaa ttgaattgtc
     2521 aaggaataac acaagaaaat attaaaattt atactcttcg gaaatctctt caaactaggt
     2581 cagtgccgcc ttgccctaag tctaggttac tgacttggtc agttctatag tagactgaaa
     2641 ctataatagt acacctctac ttctaaaaca ttgttagaaa tcgatttaac tgtcccgatc
     2701 aatttgtcct attcttattt cattttacta tatctacaac ctcaaagcag ggttttgagc
     2761 tatctatggc caacttccta gtttgctctt tagccttcca ttcaaaagtg atgctatctt
     2821 tcttagcttg aatataaaat atcccattta ctatatttaa atttattgat atgttgtaaa
     2881 ttataaatga aagaacaaat accttgtcat acaagcattc gccagggata tttacctgaa
     2941 tatcgctcat atggcggatt gaaactaaaa cactacaata tatttcttaa atagaccttc
     3001 tataaaagct agatttaacc tcgataaaaa tagatgcagt gcttctaaaa tactggaata
     3061 gggcatatag gtaatcgtag acaagtgttt tatagattgt ctcgcaggag atctaatgat
     3121 gtatagcaag catcactaaa catatgggat attcgtatta ttataatatc aacatgctat
     3181 aaattctatc atgcaaaaga atgactagaa catgaaagac aggcacaaaa ctttgaacaa
     3241 tattctgaaa acaaaaaaag acgcgagttt ccacaatctc actcatggaa actcacgtct
     3301 ttcaaaaaat agggtgaatt gaaaactaga acaagacact agattttcta aatgatgtct
     3361 agtaaggatt ctaaatgcta caccaaattg ctcacatctt atttcaaacc acgggactcc
     3421 cacaagaaag gaaaatccta taaaaattcc ctctctgagg agaaagaggc ctcaactaca
     3481 ggtgtaaact attatcaatt gaaaacaaca gtttttacac tcaattagac tttttaggga
     3541 caggatcact ttcgcttgac tgtagtttgt catttttttg ataaagttag cactttttca
     3601 gaaactgttt tgaaagtctc aatgatatag tctacttctt catcgcttaa tttagtatga
     3661 agagggaggg taatttcatt ctcaaagaag gcataggcct taggatagtt cgtcatatca
     3721 aatccaagat tcttataggc tgtcaagaga ggaagcggtt tgtagtgaac attacttgca
     3781 attcctgctt tagccaattc ttggatgatg aggttgcgtt cttctaggct tgctccttct
     3841 acacgggtga tgtagaggtg gcgtgaagat tcgacagttt cagtcttgtg tgccaaagga
     3901 tggatgcgag aacctgcaaa accactatca tagcggtcca caatgtcctt acggcgttgc
     3961 aacaaacttg gatagcggtc caattgtacc aaaccaagtg aagccatgat atcggtcatg
     4021 ttgcacttat aggctggtgt aacgatatcg tattcccatg accccagttg catcttggca
     4081 agagcatcct tagtttgccc gtgaagggaa aggatttgga attccttgta catctcttcg
     4141 tcatcaatca ctggattggc tttccaagtc gcacttccac cttctgccgt tgtaaagttc
     4201 ttaacggcat ggaatgagaa ggaagtaaaa tcagcgatag aaccagaagg ttgtccttta
     4261 taagtagatc ccaaagcgtg ggcactatca gagacaatga caatacggtt aaaggccttt
     4321 tgccacttgc ttgaagcggt aaagaagtca cgttttttct ccacgacttg gaacaaacgg
     4381 tcataatcgc aaacaatccc tgcgagctct actgggataa tcaccttagt tttctcagtg
     4441 atagcttgct caagcaggtc atagtccatc tcaaacgtat ctgcttggat atccaccatg
     4501 acaggggttg ctcccacgtg cgtaatgaca ctacatgaag ccgtataggt catggctgga
     4561 acgatgactt catcaccagg tcccacttcc aaaacgcgta aaatcaactc cagagcggct
     4621 gtcgcagagt tgagacaaac agtcttaggt gtctgtgtgt aaagagacaa gcggcgctcc
     4681 agttcttttg ttttaggacc tgttgtgatc caaccagaac gcagggtatc cgctacttca
     4741 gcaatttctg cttctgtgat atcaggcggt gaaaatggaa tattgtaatt tggcattgat
     4801 ttgctccttt tatctgtact cattttctta tgactacttt attttagtac ctcaaacacg
     4861 gtttgaaaca tgattttgat gtccccaaag aaactaaact ctcggagata ggcgaggtta
     4921 tagcgcatct tttcaggaag aacatgctcc acataggcct gatcaactga cagacctttc
     4981 tccgtcattt gactgatgat ggtgtcctca tccttgtagt tgatgctggc tggagaggta
     5041 attcctgctt gcaagagcaa ggttgccatc atttcagggc tatactgctc tgtataacgt
     5101 ggcacttcag gtcgtgtacc gacaaaggac atctcacctt taaggacatt gaccaactga
     5161 ggcagttcgt ccaaacggac acgtcggatg aaatttccaa ccttggtaat acggctatcg
     5221 ttagcagaag tcaccagact tcctttttta tccgcatccg tcaccatggt acggaacttc
     5281 caaatcttga accgacggtt gtactgggtc acacgctctt gcttgtaaat cactggccct
     5341 ttgctatcca acttgatcca aatgctcaag atgagaaaga tgggagaagt tagaaccagt
     5401 aagaccaagg ccaaaaccca gtccaagcaa cgcttgaaaa tcagcgaacc cttcctttta
     5461 gagacaagct ggtagtaaga ctcaacctcg cttgatttca tttccacagg caagtcttcc
     5521 catttcagca tgctgttctc ctttgttttt attatactat ttgtcaacat ttttcattat
     5581 accacaaaat ggaaaaggcg gtgaaagaaa tctgtaattt gaaggatttc cttctagtac
     5641 tcaatgaaaa tcaaagtaca gctttgagat tgcagataaa gctgacatgg tttaaagaga
     5701 ttttcaaaga gtataggcca tggcccctgc ctgcaaacta tacatcttgt gataggttcc
     5761 tcccagagtc aagagttcct catgggttcc actctcgata atgcgtccct tatccaagac
     5821 atagatgcag ttggcgtctt gaatagtaga aaggcggtga gcgatagcaa tagttgttcg
     5881 gccctgtctc atcttcgcca gagaagcttg aaccaaactt tctgtttcag agtcaatatt
     5941 ggctgtcgct tcatccaaaa tcaggatttt aggctggctg gcgactgttc tagcaaaggc
     6001 aagaagctgg cgctgcccag tagagaagct cgaaccacgc tcggaaacag gggagtcgta
     6061 cccctgagga agttcttgaa taaaggaatc tgcatccaca aaggctgccg cagcctgaac
     6121 ctgctcatca ctgatttctt ggtacatggc gatattggac ttaatagttc catgatagag
     6181 gaagggttcc tgtaaaacca aaccgatgtt ttttctcagc tcttcttgac tgaaatccct
     6241 gatatccaca tcatccaaga gaactctccc tgactggaat tcataaaagc gcatgaggac
     6301 attgataata gacgatttcc ctgaacctgt atgacctaca aaggcaatgg tttcaccctt
     6361 attaacagag aaagaaatgt catccagaat cggatgttta ccgtcatacg agaaacacac
     6421 atgttcaaaa cggatattgc cttctttgac tttggcttgc ccattttctt gaaggggctc
     6481 ataggtcctc tcatcgatta aggcaaagac acggcctgca gaaaccatag acgtttgcag
     6541 tgttgaaaag ttttgcgtca cctcaatcaa agggtcaaag aggcggttga tgtactggat
     6601 aaaagcatac atggtcccgg ccgttatccc gatagaaaga ccacgatagc caaaataggt
     6661 catcaagaca gcataaccta gaagtttcaa caaactcatg gcaggtctca aaaagagggc
     6721 atccaaggct acagaacggt tggcataggc caagtgctct tggttgattt catcaaattc
     6781 tgcctgcagg cgcttctctt gattaaaagc ctgaataatc ctgattccct cgatattctc
     6841 tgccagctta ctattgatat ctgacaagag acttctggtt ttctcgatga ttttcactga
     6901 cttttttcga tagagattga ccaaaaggaa aatcaagggg agaaagagca agactaatgc
     6961 tgtcaaacga aaatccagca ccaacatggt ataaagggtt gtcagaaaga taaaaactgc
     7021 tgagataaag ctggataaaa tcccagaaaa catatcacta atcgtctcgg tatcgttggt
     7081 caaacgagaa acgatagaac ctgctggcgt cttgtcaaag taagacatgc ccagtttctc
     7141 catattggca aaggcatccc gacgaatatc cctaacaata ctgtaagaca cgcgcgcaaa
     7201 gagaagattg ccgacatact gaactacagt ttgtaggatg tagagaccat agtagaccag
     7261 caaaacggtc acggctagtt ggttaagatt gctgagatac tggtcgataa agtgggaagc
     7321 cacaagggga atgacacttt taatgaccgt cgtcgctagg agaaaactga gtgccaaaaa
     7381 ggtaaggagt ccataaggct tgagatagga catcaagcgc ttcaatacag tccattgttc
     7441 ttgtttattc tgcatcttct tctcccttca tttccagctg ctgagactgg taggtttggg
     7501 cataccagcc atccaaagct agcaagtctt cgtgcctgcc tcgttcgata atttgaccat
     7561 tttgcaggac taaaatcaaa tctgcatgga caactgcact caggcgatgg gcagtgataa
     7621 tggttgtctt gtcctttcgc gtctccttga ggttgtcgat aatcgcatac tctgtcttgg
     7681 catctacggc ggataaggaa tcatccaaaa tcaagatatc agggtctaaa atcatagccc
     7741 gactcatagc caaccgttgc ttttgaccac cagaaagact gactcctttt tcaccaatca
     7801 gcgtatcaaa tccttgaggc atgtctacaa tatcttggta aactcgggct agcttagtag
     7861 cttcctcgac cgctgaaagg ggcaagttag gattgccaaa gcggatattg tctaggattg
     7921 aagtcgcaaa aagaaactgg tcctgaggaa catagcccat gagactgcga aggtctgtca
     7981 gacgatagtc ccgaatatcg tgaccgttta gataaatggc acccttatcc acatcgtatt
     8041 cacgcaagaa gagcttgatt aaggacgttt tcccagagcc tgtctgccca accaagccca
     8101 gtgtttgccc ttttgccaaa ctaaagtgaa tatccgtcag tgtttcctca ttttcaaaag
     8161 caaagctgtc aatggcatac tccaaacgcc cattttcaat accatccaga ggaaactcag
     8221 ggtcttgtac aggagattcc tgagacaaaa gattttcaat ccgctggtaa gaaaccttcc
     8281 ctcgctgagt agtattaaag aggaagccga tggccataag aggccagacc agcatatcca
     8341 aatagctgat aaaggtgact agattaccaa ctgtaatctg cccttcctga accatcaagg
     8401 agccaaccaa aagcgttaaa acataggacg aaccaacaaa caagagaacc atagggtcaa
     8461 agagactatc atatttcatg gtttgcaggt tcttttggaa ggttaattca ttgactgcct
     8521 gaaaagactt caactcgtct gcctgataac cgaaagactt ggtcactttg atacctgata
     8581 cggactcctg taccttgtta ttgagttcag aaaaagcagc ttgggattcg ccaaaggcct
     8641 tatgagtctt tctccctagg cgactagtcg cataggccat gaaaggtagg gggagaatgg
     8701 caacaagagt catctgccat gagatgctaa agagcatggt caacaaagtc accagagccg
     8761 tgatagaggc atccaccgca gacatgacac cgccacctgc taaacgagtc aaggcattga
     8821 tatcattggt tgcgtgtgcc atcagatcac ccgtccgata ggtttgataa aaggctgacg
     8881 acatttttgt gaaatgctta aacaagcgag accgcatgat ctgtcccaag caataagagg
     8941 tcccaaggat atacatacgc cacacatagc gcaaatagta cataccaaag gctgcaagta
     9001 gcaagtaaaa taggctaaga aggaggtcct gctgggttaa ttgccccgat gtgatggcat
     9061 caataacccg ccccataacc ataggaggaa tgagattgag gacggaaacc aagaccaggg
     9121 ccacaattcc gactagataa cggcgttttt ctaacttgaa aaaccaccaa agtttttgaa
     9181 taatggacat aaaatccctt tctgattgca aatggaaacc tgaggccaat actcaatgaa
     9241 aatcaaagag caaactagga aactagccgc aggctgctca aagcactgct ttgaggttgt
     9301 agatagaact gacgaagtca gtaacctaca tacggcaagg cgacgttgac gcggtttgaa
     9361 gagattttcg aagagtacaa gaccccaggt ttttcttatt cataagttac gactgtaaca
     9421 gcacccttgt catattcagc aataaagata ttggctacat tgtcatgccc ttgtttactg
     9481 aggttatcaa gcaaccactc ttcgctacga ccaatcgatt ccaagacatc tacttgaatc
     9541 acaccgtcag tcacaactga atacttagga ttttcatctc ccatttgcac aacgatgagt
     9601 tgcccatttt gctcttgcac agctcgtttg acttgcttca tctggaaaat cccttggcta
     9661 cgaagtttga gggctacatc cgatgcagac aaaccaactg aacgacaggt ttatggggca
     9721 atattcccat ttttgataag gagagttggc ttaccatcaa tcaaacgttt cacaaagtga
     9781 acattgttgt tgagccattt gagagtcaag accagtttga ttaaaatttc gatataatta
     9841 agtgtcattt attcacatcc accagttcaa ttgcgtctgt cttatacaat tcgactttct
     9901 ctaacaggta cttgtctggc tcacttccgt ttagggcacg ataatagcga tctcccacct
     9961 tgataagtgc gccatctgtg tttgtggaag tattaacata gacttctgac ttgtctactc
    10021 ccaaatcttt ggaaacaacc tcgatgaaat gaagtgaagt ttgaaattta ttgttagaaa
    10081 cttgattgtt ttgataagtc gtgatgctga ccaaaagcag agctaaataa ggccagagct
    10141 gaaatcatga ccaactcacg aaattcggtt ccctttttat catggtatgc cttaaaagca
    10201 aaaaaactgt cacagctaat agaacaatcc caaagccaac catgatacca ttttgctgac
    10261 cgatttggct gagtacatag tcataagagt agaatttcat gtattttcac tccctttcat
    10321 aaaatcattc ttaattataa acgaaagaga gtaatttttc aaactatacg ttggggaaat
    10381 agatcttttt ttggtataat aaaatctata atctgaatga aaaaggtaac tttatgaaac
    10441 ttatctcatg gaatattgat tccctaaacg ctgccctaac tagtgactca gctcgtgcca
    10501 aattgtccca agaagtccta caaaccttgg tcgctgaaaa tgctgatatc attgctatcc
    10561 aagaaaccaa gctttctgcc aaaggaccta caaagaaaca cgtggaaatt ttagaagaac
    10621 tcttcccagg ctacgaaaac acgtggcgtt cttcccaaga gcctgcccgt aaaggctatg
    10681 ctggaaccat gttcctttat aagaaagaac ttacacctac tatcagcttc ccagaaatcg
    10741 gtgccccttc taccatggac ttggaaggtc gtatcatcac tctagaattt gatgcatttt
    10801 tcgtaaccca agtttacact ccaaacgctg gtgacggtct caaacgcttg gaagaacgcc
    10861 aagtctggga tgccaaatat gctgagtatt tggctaaact agacaaagaa aaaccagtcc
    10921 ttgcgaccgg tgactacaac gtagcccaca atgaaatcga ccttgcaaat cctgctagca
    10981 accgccgttc acctggattt actgacgagg aacgtgctgg atttaccaac cttttggcaa
    11041 ctggatttac agacaccttc cgccatgttc atggcgatgt tcctgaacgc tacacttggt
    11101 gggcacaacg cagcaaaact tctaaaatca acaatacagg ctggagaatc gactactggc
    11161 tcacaagtaa ccgtatcgct gacaaggtca ctaaatctga tatgattgac tcaggtgctc
    11221 gccaagacca tacaccgatt gtcttggaaa ttgacttgta aggattttct atatggacta
    11281 caatgcggtc attcccgagt tgcttgtatc gaatatcgaa cagtcccggt ccttctactg
    11341 tggtttactg ggttttagga ttgaatacca acgtccagaa gaaaactttc tctttctctt
    11401 gaagagtgtc aactaatgtt agaggaggga acaaaggatc aactagctga actgacctat
    11461 ccctttggtc gtggagtcaa tctctccttt ggcataaagg atgtttcaaa actctattaa
    11521 agagtgatga aggcaaacta tcctatttat cgtcccttga ccaagagaaa gtttcgtgtc
    11581 agtgatccct atatctatcc tcatgaattt gcagttttgg atccaaatgg ctatttttta
    11641 agatttagcg agtagaataa taaaaattgg gaaaagtctt taaagttaga aaaaggcata
    11701 ttgtcaggtg tctaaaaact tgatagtatg ccttttatga tggaaaaatc ttctaatact
    11761 attcgaaaat ctcttcaagc cacatcaacg tcgccttacc gtaggtatat gatactgact
    11821 ctgtcaattc tatccacaac ctcaaaacag tgatttgagg ttgtggatag cttcctagtt
    11881 tgctctttga ttttcattta gtataaatgt tagcttacaa cggagttttt gttcaccccc
    11941 tcttctgttt gttcgttttt taaaccaaaa cactaacaaa atagttgatt tataaagtta
    12001 tttagtgtaa aataaaaaca ttggctcaag cctatttaaa attgaatatc gttttacttg
    12061 tttatgtcgt gaattggcac gacgtttcta caaggtgccg gaacacctaa caataagtaa
    12121 gtcagcagtg agatatggcc gtttttgcca tgtctattta ggggacttac ttagagatta
    12181 agtaggtctt ttttgaatat ttttaatatt tcccttaatt agtgcggacg ggaggtgaaa
    12241 ttatcctgtg aataatttca ggaatccagg gaatttcatc cctaattttt gagcccctag
    12301 ctctttcatt tctaggctta ggctaaaata gttccccgaa ctattttact ctcaaaaatc
    12361 ccgtcataga caataacaag attattgtct atgataccac tacaacggga aatatttgat
    12421 aagactcgct tcgctcgtaa tagttttatc aaatatatag tattagcaaa agggatcact
    12481 atagaaacat ttaaacaaca agtaaattag cttttagact ttaggaggtc ttatgaaatt
    12541 attagaagag cgcatcctca aggatgggca tatcttgggt gataacatcc tcaaggtaga
    12601 ttccttttta acccaccaag ttgactttag cttgatgcga gagattggta aggtttttgc
    12661 ggaaaaattt gctgctgccg gcattaccaa ggtcgtaacc attgaagcgt cgggtattgc
    12721 cccagccgtt tttacagctg aagccttaaa cgttcccatg attttcgcca aaaaagctaa
    12781 gaacatcacc atgaacgaag gcatcttaac tgctcaagtc tactccttta ccaagcaggt
    12841 gaccagcacc gtttctatcg ctggaaaatt cctctcacca gaggacaagg ttttgattat
    12901 cgacgatttc cttgctaatg gccaagctgc taaaggcttg attcaaatca tcgaacaggc
    12961 cggtgccaca gtccaagcta tcggtatcgt gattgagaaa tccttccaag atggccgtga
    13021 tttgcttgaa aaagcaggct accctgtcct atcacttgct cgtttggatc gttttgaaaa
    13081 tggtcaggtc gtatttaagg aggcagatct ctaatgcaaa ctcaagaaaa acactcgcaa
    13141 gcagccgttc ttggcttgca gcacttacta gccatgtact caggatctat cctggttccc
    13201 atcatgattg cgacagccct tggctattca gctgagcagt tgacctacct gatttctaca
    13261 gatatcttca tgtgtggggt ggcaaccttc ctccaactcc aactcaacaa atactttggg
    13321 attggactcc cagtcgttct tggagttgca ttccagtcgg tcgctccctt gattatgatt
    13381 gggcaaagcc atggtagtgg cgctatgttt ggtgccctta tcgcatctgg gatttacgtg
    13441 gttcttgttt caggcatctt ctcaaaagtg gccaatctct tcccctctat cgtaacagga
    13501 tctgttatta ccacgattgg tttaaccttg atccctgtcg ctattggaaa tatgggaaat
    13561 aacgttccag agccaactgg tcaaagtctc ttgctttcag ctattactgt tctgattatc
    13621 ctcttgatca acatctttac caaaggattt atcaagtcta tctctatttt gattggtctg
    13681 gttgttggaa ctgccattgc tgctactatg ggcttggtgg acttctctcc tgttgcggta
    13741 gctccacttg tccatgtccc aactccactc tactttggga tgccaacctt tgaaatctca
    13801 tctattgtca tgatgtgtat catcgcaacg gtgtctatgg ttgagtcaac tggtgtttat
    13861 ctagccttgt ctgatatcac aaaagatcca atcgacagca cgcgccttcg caacggttac
    13921 cgcgcagaag gtttggcggt acttctcgga ggaatcttta acaccttccc ttacaccgga
    13981 ttttcacaaa acgttggttt ggttaaattg tcaggcatca aaaaacgcct gccaatctac
    14041 tacgcagctg gtttcctggt tctccttgga ctgcttccta agtttggtgc ccttgcccaa
    14101 atcattccaa gctccgtcct cggcggtgcc atgctggtga tgtttggttt tgtatctatt
    14161 caagggatgc aaatcctcgc ccgagttgac tttgctaaca atgaacacaa cttccttatc
    14221 gcagctgttt caatcgctgc aggtgtcggt ctcaacaaca gtaatctctt tgtcagcatg
    14281 ccgacagcct tccaaatgtt cttctcaaac ggaatcgtcg tagccagcct actcgctatt
    14341 gtcctcaatg ccgtattaaa tcataaaaag aaataagaaa aagaggtgcg agcctctttt
    14401 ttgtgtgaca aaataaaaac atctacctat tcatatatgc tagtgtcata gtcctgaaaa
    14461 tcatctgcat caagaacaat ttcacaactc ttatactttt ctcttacaag tcgttcggct
    14521 tcatctggat tttcagcctc tatacttact aaacgtgata aagtttctgt aatttctact
    14581 gtatactttt tcagttttag attgctttcc aataattcac ctattaacaa taatctatga
    14641 taggagctat gtagccactc tggcaattta tctcctactt cccacccata tttttccttc
    14701 atcaaagcta gttgtttttc gtcaccaaat ttcatatttt cagataacca tctcacacaa
    14761 tcgggatctg ataaggtaca gacgattaaa cttaggttat cgtaacggct ttcagtttca
    14821 taatcaggcc agatgacttt taagaaatca tacacctctt ctgatgcaac aagttgtttc
    14881 gttttcataa tttccgatac tttcctctac ctttaaattc tattatttct ttgtctctta
    14941 atatttgaag ctgttgccta atcttttctt tgatatgatt gttcttaaca aagatatttt
    15001 ttaggtcact ttcaaaacga tacatatctt caagggtaaa ttctgaaccc tctatcttat
    15061 ctatacaatt tagaatttct attgtccaac ctcttgatga cagagagctc ttccttaaaa
    15121 ataaaccttg cttaaattct tttgtaactt tttctggatc tctaacttgt ccatcttgca
    15181 caagaaatat ccttccttta gaaggtactt gtgataaatc aatgttacaa ccaatccaac
    15241 ctgctcgtct agcagttggt gcaagtggtt ttctttgaat aatcgatttc ggtgtaacaa
    15301 attgcttcgg aaggacaaga aagttattta cctcaaaatt ttttgtgtaa gttaaaaaaa
    15361 agaaattagg attattatct gcctgcacac gcttcatcat cgttgcataa gcaccatcat
    15421 tgattgttga tgaaaaattt ccttttttgc tctttagttc aaactcctca ctacaatgat
    15481 tacagtaaaa atctgctaca ggccgattat tttcaaaatg atttaaggga ttgttcccac
    15541 aattagggca ataagactga cgataaaccc aatcctccgt taagatacgt gccttttggc
    15601 tattactttt ataggtttct actaattcta aattaaagtg taattccatt taaaaattcc
    15661 tcactaatat gagaactcac tcgatataag caattaaaat ctactataac tagtatacca
    15721 catatatgta cctattacat ttgtatttca tcactctctt ttatatttcc ttctaacata
    15781 tctcataaat taaaaatgag tgagataaat ttatcccact cacctttctt tatatactta
    15841 cccgtctttc ctcagacctt tggcctgtga caaacatggt aaaggttgcc ttacagacat
    15901 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    15961 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    16021 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    16081 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gatgagttca
    16141 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    16201 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    16261 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    16321 cgacctgttc cacaaagcgc ataaaggctg tctgcccttg ttctgtctgc ttgtagactc
    16381 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    16441 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    16501 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tctacttctt
    16561 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    16621 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    16681 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    16741 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    16801 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    16861 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    16921 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    16981 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    17041 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    17101 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    17161 catagggcga atactggaaa ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    17221 ggttggtgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    17281 gacactgagg ataattacta gcttgcacca acttggctgc cgcaatctct ttcggatcct
    17341 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    17401 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttctga ctgagttgat
    17461 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    17521 cctgactcgg acaaggagtc accaagtcca tcaattcagt accaaggatt tcacgcgcag
    17581 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    17641 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    17701 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    17761 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    17821 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    17881 gtttgcctac agcttcctta aaggcctcaa cagtatcttt ttgaaccaag gcaatggcac
    17941 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    18001 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    18061 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    18121 ctttaagggt acgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    18181 ctttaatcaa atagctatat tggtcaacgg cccactcgtc caattcaccc agggtctgaa
    18241 tatccaaggc aacttgcaat tcttccactg ctttttcaca ctcagcacga cgttcattgt
    18301 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    18361 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    18421 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    18481 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    18541 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    18601 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    18661 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    18721 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    18781 gtaaaacttg gtcttcacgc ttgcgagctg caccataagt tcccaaggaa atagcagctg
    18841 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    18901 aaaagaaggt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    18961 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    19021 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    19081 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    19141 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    19201 cccgtgttct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    19261 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    19321 ccaagcaaaa gattgccatt attcaatggg tcagcgaaca aggggagcta gacgacctct
    19381 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tacgatatct
    19441 tgcgctattt taatgaccac ccttttaccc taagcgagga agtgattggg attctctgca
    19501 tcggaaagtt tagtcgagct cagatttctg cctttgaaga ataccaaaag cctcttgtat
    19561 ttctagacag cgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    19621 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    19681 caggccttga agaaacaact gaccaagaag aaatcattga ggataagcgg ctggaaaatt
    19741 tcagaaacta cagtcaagca aaaggaatct atcatgatga actgatcttt caaggaaact
    19801 ttactgccca gtctggctat gacttgatga aggaagccat tcagaacttg ggagaccaac
    19861 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    19921 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    19981 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    20041 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcggaaaatc cctagcctga
    20101 ccatgctggg aaccaaactg acgttaagag aaagtactct aaatcaagaa taggataaca
    20161 taaaaaacga ataggagttt tagaactcct attcgttttt tattcgatta caatcataga
    20221 cttaatggtc ttacgttcat ccatatcttt gtaggcttgg tcgatatctt ccagtttata
    20281 acttgaagta aagacgcgac ctggattgat atcaccatca aggacggctt ttagtaaaaa
    20341 ttgcttatcg tatgttgtag cagaagctgc cccacctgct acagagatat tttgcataaa
    20401 tgtcgaacca agagcacgat tattatagtg tgggactcct acaaagccca tacgccctcc
    20461 attatgaaga acacctagcg cctgttctat agcagcctcc gtaccaacac attcaagtgc
    20521 tgcatctgct cctccaccga ggatttcacg cacctttgta attccttctt gaccacgttc
    20581 tgcaacaaca gctgtcgcac ctgactccat agccatcttt tgacggtctt catgacggct
    20641 cataaggata atttgtgatg ctccacgcat cttagccgcg atgacagcac attgaccaac
    20701 agccccatca ccaataacaa caaccttgtc ccctttttga acatttgcaa cacgcgccgc
    20761 atgatagcct gtcggcatga catctgcaag agtcaaaagg gacttgagca tcccttctgt
    20821 atagtcagaa ggttgaccag ggattttaac cagcgcccag tttgcatagt ggaagcgaat
    20881 atattctgcc tgaaaatcac cccccaaatt attgccaata tgattgtcgc aagaaccgtc
    20941 aaatccagca agacaggcat cacactcacc acatccatgt gtaaaaggga caatcacaaa
    21001 atcacctggt ttcaccgtcg taatggcttc cccagcttct tcaacaatcc caatcgcttc
    21061 gtgtccacta tttttgtgtc cagctttcgt ttctggatta cggtacctcc ataaatctga
    21121 accacaaacg cacgaacgaa ccacacgaat aatcacatca tccgcttcta ttatttgcgg
    21181 acgttcaatg ctagcaagtc caacctgacc tgcctttgta tatactgctg atttcattta
    21241 aaattttcct tccttataaa gtttaatttt gagatttaaa cgatttaaag ctgtctgtag
    21301 ctgagacaag cgctcctcta atttttgctt ttcctcttct aaaataccaa gcctctcctc
    21361 tctcgtttca tctccctttt ggtagagcga catatagtca actaaactat ctacagagac
    21421 acccgccgaa cgaaaacact taataaattc cagcgcttcg atatcctgaa cttgaaaatc
    21481 acgaatccca gtagcagtac gagtaatcgg tggcacaaga ccaatccgtt cataataccg
    21541 aatcgtatcc gctgaaattc ccaacaaatc actggcggat ttaatattca cacgctaacc
    21601 tcctctcatt tcattcactg aattcacgct attctaactc acttatctta ttatataact
    21661 ttgagttgac tccaagtcaa gcattttgta tctaatcgaa aaatttttat cattaacaat
    21721 catatatctg gagtttatac aatgctcttc tcttaccaat ttttgaaata tttaaataat
    21781 aaagaaatta ctctattcca aataagatag tacccaagta tttttcactt ttttctaatg
    21841 ttgatgctca taactccgtt ccaagtcaca cacctttcgc ttatgggttt ggtgagtttc
    21901 taggtcagca tcaatttcaa tggtaatatt ttgaaaacca caatctttta ggaaaattcg
    21961 aatagactct ttacaagttt ccatatgttc catttctttt agacaaacat ggacaatggc
    22021 atttttttcc aaagcatcca tagtccagag attaagctga ttaaggctgg ccacattgtt
    22081 caatcgctcc aggccactct ttacttgctt gatatcaaga ccttctggca cagcatccaa
    22141 gaaaatcttg agtgtagacc aaaaacgtga aagggctttt gaaagaataa agaaagaaat
    22201 gacaagggac aaaagaggat ctaggatata ccagtccgta aatcgaagaa caatcgccat
    22261 caggataaca gctacccacc ctagcgtatc ttccagaaaa tgcagactca gaatagactc
    22321 attctttgtc tttcccttac caaccaccag actcgctaac agattgatag taatcgcaat
    22381 aattcctaac cagagaatcc cctcatcatt gactggttgc ggatgcaaaa tcttcgtgac
    22441 attttccaaa atgactagaa cagagcccgt tacgagaatc acagctatta ccaaggctcc
    22501 tagcaggcta aaccgcttat agcccaaggt gtactgattg tcttcttcac gattggagat
    22561 tgtttctaga aaagctgata ttccaattgc aatcgcatct cccaagtcat gcacagagtc
    22621 agcaagaaca gcgctagaac caaatactcc acctgcaata aactcaacaa tggcataagt
    22681 caaatttaag aaaaaagcca cccaaacagc atattttgcc ttcatatttc tcattccttt
    22741 gttataatag atttatgaac accttgttca ttatcattat ccactaaaac tcaaagaaag
    22801 gatagaagca aaacgtcagc tttattcagt tctgaacaat ttgccttaag tgtccatatg
    22861 actaacattg accgccgtat cagcaaaacc aaaaaagcca tctatcaagc ttttatacaa
    22921 cttttgaatg ctaagggcta cgaggccact actgttcagg atatcattga tctcgcagat
    22981 gtgggacgat ccacctttta ctgtcactat gagagtaagg agcttcttct ggaccagctc
    23041 tgccgctacc tcttccatca tctttttgaa agagagcaag ccatttcaac cgagaattac
    23101 ctcgcccacc tctttctcca ttttcataaa aaccaagacc atatcaccag tctgctattt
    23161 tccaaaaatg actacttcct ccgtcaactc cataaagagc tagaacacca tgtctattcc
    23221 gtgctagctg ataatttaaa agaagcccac cctaatctgc ctacttctta cctccaacac
    23281 ttggtcatgt ccaactttat cgagacattg acctggtggc tcaaaaaagg tcaagatttc
    23341 acagaccagg aagttgtcca attttatcta gaccttctca ttcctaaaaa ttgaatatag
    23401 agtaaagctt cagttgtctt atttctaggt tactgagttt tttatctttt caacaacaaa
    23461 agaggacccg ccgatcctct ttttcatact ataaatcctt gattatcaac tatatctgtt
    23521 ttaatcgaaa tctcaaaaca gcactttcaa acatcttttc ctagttaagt aaatcagtat
    23581 tctgcttagc tgccttgctc cattgatacc aaccaactag actgttaatg agataaatta
    23641 gatatttccc ttgaatttgc aggctttctc cccaccagag atagattgaa aaaacattgg
    23701 tagccgccca gaatatccac tgttcacggt aaacagctgt catgaggatt tgccctaccc
    23761 cattggttgc atctgtgatt gaatcacgat agggacgatt ggcaccaata gactgataaa
    23821 tgaagccaaa ggccaaccac caaagcacac taatggaaag atactttgtc cagcccttgc
    23881 cgtccagttt acgcgcgaca aactcctgct tttccttctt aaactgtgcc tgataaatcc
    23941 aaactagaag tccaattggc tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat
    24001 aaaagccttt ctgtagggcc aaaataaggt aaataacaga gttaatcaag ccaaaaagat
    24061 aattacttgc tcgaccttcc gatacaaaga ttacacagat aatccctgtc aagctacaaa
    24121 tcatcccaat ccagtcaaca atacgatgtt cgtaaaccaa ctccagccag agaggaaaac
    24181 ttcctaaaac cagcaaataa atccactggg caaaactacg atgggcaaag aggtcatccc
    24241 agatagcctt catagttcct gaaaatccta aatcagccat agccgcaacc atacgacggt
    24301 aaccacctga catttcacct agggttgttt tgatattttc aattttcttt tgcaaataag
    24361 tatgcatcat ttctcctttt gtttttaaag agccgtgtct ggatagactt tcggacgcaa
    24421 cgctctatta gataatgaac tgcctataca caagatttct aaccttagtc gacatgagct
    24481 gaaacctctt atttgttaag tagttcacaa aatattatac acctatttta tgaatagtca
    24541 actgtcttta cagtaaaatt ttagaaaatc atgaaaattt tctctttctt tccattttaa
    24601 gtgacattca gtcattctca catcaaaaaa gcccagacga aattgtctga gcattctttt
    24661 atctagtcgt ttaaggaagt tgagttcagt atgtttaaag tctctgtccc atcatttctt
    24721 caacaaacct tgttcttgga gaaactcctt ggctacttgc tttgctgact tgccttcaac
    24781 accgacttgg tagttgagct ggctcatctg gctttctgta atcttaccag ccaatgtatt
    24841 aagaactctt tccaactctg ggtgtttctt gagaagagct tctttcatga gtggagcccc
    24901 ttgataaggt gggaagagtt gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa
    24961 ttccgcatca gtcgaatagg catccgtgat ttgaatatcc cctgactgaa ttgcctgata
    25021 acgaagagct ggctgcatag tcgccacatt gagattgaga ccatacattg attgcaagcc
    25081 cttatttcca tcttcacggt cgttaaactc aagcgtaaag cctgccttca gctgcccttc
    25141 cacttttttc aaatccgaaa tggtcttcaa gccatattct tgagcaatct ttttcggaac
    25201 agctacagca taggtatttt gataagacat aggtttgaga taggctagat gatcctgctt
    25261 ggcaatacca tcacgcgcca cttgataaac ctgctctggc tcatgactca ccttgggtga
    25321 tggttgaagc aaactttcag tcaccgtacc ggtaaattca ggataaatgt caatatcacc
    25381 ttttttcaga gcttcataaa ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt
    25441 catgctggta ttttcttcaa tcagcaattt atacatatta gccaaaattt ctggttctgg
    25501 gcctattttc ccagcaataa tcaagttttc cttctctttt tgagccaaaa gggctggact
    25561 ataagacaga cccagtaata aagccatcaa ggcaaaacca gagaaaatcg tccgcaattt
    25621 cgctttttcc attactttta gtaggaagtt aaaggcaata gctagcactg cagaagaaag
    25681 ggccccaatc aaaatcaaac tggcattatt acggtcaatt cccaacagga taaaggaacc
    25741 cagtccccct gccccaatca aggtcgccaa ggtagccgta ccgataatca agaccgctgc
    25801 cgtccgaatt ccagacatga taacaggcat ggcaagtgga atttcaaact tcttgagacg
    25861 ctcccatctg gtcatcccaa aggcaatccc agcctcttga agactcggat caattccctt
    25921 cagcccagta atagtatttt gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa
    25981 tgccggtaaa gtcccaattc ccatcaaggg aataaagagt cccaacaagg ccagagacgg
    26041 gatggtctgg aaaatccctg caatctgtaa gacccaatcc gccaacttct catgatagcg
    26101 aagataaaca gccaagggaa tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa
    26161 ctgcaaatgt tgagataggg ctgtcaacca atcaccaaaa cgatcctgaa aagttgcaat
    26221 taaattagtc atgaatacta cctccaaaca agtctgcaac aaagtctgtt gcaggagctt
    26281 ttaaaatagt ctcaggattc gacacctgac gaatctctcc atcctgcaag acagcaatac
    26341 gatctgccaa ctttaaggct tcatccgtat catgagtcac aaaaatcgtt gtcatcccaa
    26401 actctttatg taattctttt gtcagagcct gcaactgctt gcgagaaata gcatccaagg
    26461 ctgaaaaggg ttcatccatg aggagaatct tgggctgacc aatcatagct cggacaatac
    26521 cgacccgttg ctgttctcca ccagatagct cacttggaag tcgatgccca tactcagcta
    26581 ctggtaaacc aaccttagcc aaaagctctt ctgttttttg agcaatttct tccttagtcc
    26641 aacccttcat ttcaggaatg agagcaatat tttcctcaac tgttagattg ggaaagagag
    26701 caatagcctg taaaacataa ccagtagaaa gacgaagttc acgctcatca tagtctttga
    26761 tgcgcttccc atccatataa atatttccat cagttggttc caaaagacgg ttaatcatct
    26821 tgagcatggt cgtcttacct gacccagaag gccctactaa aaccataaat tccccatcct
    26881 caatctgtaa gttgacatct ctcaagacat ccttttctgt gtagcgcagt gctacatttt
    26941 tgtattcaat cattctttgt cctcaattta aaacttccct cgattagtca agtcttctac
    27001 cttaggcatg acttccttat tatcccaatg ctccacaatt ttcccgttct ctaaacggaa
    27061 gatatcgtac tgggcataag caacgccatc aatctgagtc tgaccatagc taaccacata
    27121 gtttccttgt cctaagagtt ggaaaacaaa gtcaaaagtg acactatatt cagccacata
    27181 atttttataa gcagcacttc cttgtccaat atcatgatta tgctgaatca aatcgtctgc
    27241 cacataatca ctccactgct ctagctcccc attttggaaa atttctgtca agaaacggcg
    27301 aaccagcttt ttattttctg ctttcttgtc caaatccttg atttcaaaat ctccaaaaat
    27361 ttgatctagt tggtcatttt caggtgttcg atagtagtca atgacatccc aatgctcaac
    27421 aatacgacca ttctcatccg cacggaaagt atccgtcgtc acccattgag cttctccacc
    27481 attcagatat tgatgaacat gaacaaagac cagattgcca tcctcaatgg tgcggacaat
    27541 cttaatctga cgctctggat gacgctcaaa gaaatctgca aagaaggctg caaatccttc
    27601 tttcccgtca ggaacacctg tcgaatgttg gatataggta tcccctacag actgggcttg
    27661 agcctcagca actcgtccgt cttgaatggc atggatgtat aggttgtgag catttttcac
    27721 ttgttgtgac atattctaaa cctcatttcc cttctctttc agattcgcca aaattctttc
    27781 ttgaaaacct tcaaattggt gaatttcttc ctctgaaaat cctttgtaaa agatagtatc
    27841 caatttctga ctgacacgat gccccacttc tttctgggac ttgcctaact ccgttaaaac
    27901 taaatacttc ttacgcttgt cttttccaca cggactaaca attacaagct tttgttcctc
    27961 tagctttttt atcatagtcg tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc
    28021 tgtcgcagtt gcgcagccag tttcactatt ccataaaacc gctaaaatct tgccctgttc
    28081 acccctataa agagcctcag gatcttgact cagtaacttt tgaaaaatcc gcccattcaa
    28141 caaacgaata tgatgggcta gcaaatgact atctttcata acacctccaa tttatgtcga
    28201 tatcgaaatg aataaaataa ttgtaacact catcgttcta actgtcaact atttcgattt
    28261 ggaaataatt tttgataatt atccacacca ccatactccg aatcaactaa cttttaacga
    28321 gagtttctaa attccttcgt cctccagtct acaaaagcct tccatccgta ctatcctata
    28381 ttttatgagg ggacacattt ttcctatcag accatttatt ttaaagatag aagtaaatca
    28441 taattgcttc catctgttct tttatagtat attgaagttg aactagggca ctgtatcttc
    28501 taaaacattg ataaaaagcg atttgaattt cccaatcaat ttgttcgtat ttatagcatt
    28561 ttgaaattgg aataggacac catgactgct aaaagatttc tataaattca tttgattttc
    28621 ctaatcaatt tgttcatatc ttatttcatc ccgctataat ttcaccttgc cctatctttt
    28681 tcgtagcacc cttcaaacag cctatcccct accgtttgac gattcctcac ttcgctccac
    28741 ttccattaca gaagtttctt cactactatg gtctcggctg acttctcatg attccttgtt
    28801 actactattt gaacgctcac gagataggtc ttacaaaaaa tgctttgatc cacaatggaa
    28861 tcaaagtatt ttaaagagtt cctcatacat aagcgcagaa gtcgcagttc ctctgtactt
    28921 ggcttcttct cttttgataa agcgagccaa gttgagcaac tcaggtgctg gatgtttggg
    28981 atttaggagc aattcacgat tgaccaggcc tgagagacga actgcctgca attgctcatt
    29041 tgtagtaggc agttttttag cagtctctag gagagcagca actaaatctt cactcaaatc
    29101 atgtcgagca tgattgtaaa gatcttttat aaggctttct aggtttggtt ctaccatccc
    29161 taccacctcc cttatggttt aataatgttt aatcaaatca accgttgaac gatccaattt
    29221 cttcaccaag gcttgtaaga aagcttgcgc ttctaggaag tcatccattg catagagggt
    29281 ttggtgagaa tggatataac gagcgcagac accgatagtt gttgatggga caccaccatt
    29341 tttcagatga gctgcacctg catctgttcc gcctttacca cagtagtatt ggtacttgat
    29401 gccagcttct tcagccgttg tcaaaaggaa atccttcatc tctgggagaa gcaagtgacc
    29461 tggatcatag aaacgaatca aggttccatc tccaatcttg ccttgaccac cgtagacatc
    29521 acctgctggt gagcaatcaa ctgcgaggaa gacttctggg tcaaacttgg ttgtagaggt
    29581 atgagcgcca cgcagaccaa cttcttcttg gacgttagaa cccagataga gttcattgcc
    29641 gagtttttga cctgataaag cttcagctag ctcgcttacc atgaggacac cgtagcggtt
    29701 atcccaagct tttgagatga tatttttttc attggctgtc aaaattgcag aactatctgg
    29761 tacgatggta tcaccaggac ggatgccaaa actttctgcc tcatccttgt ccgcaaaacc
    29821 accatcaaaa acgatatcgg caatggctgg catggttggt cccccctttc cacgagtcaa
    29881 atgcggagga acagaacctg aaatcacagg aatttcatga ccatcacgag tcaagagttt
    29941 gaaacgttgg ctgctaacca ccatggggtt ccagccaccg atttctacga cacggaaggt
    30001 accatctggc ttgatttcgc tgaccataaa accaacttcg tccatatgag aagcgaccaa
    30061 gacgcgcggt gcatccacag cttctgaatg tttgatacca aaaataccac ccaagccatc
    30121 tgtcaccact tcatccacat gcggtgtcaa cttttcacga agataagcac ggacaggcgc
    30181 ttcatgacct gagactgcag caagttctgt tacttcttta atttttgaaa ataatgttgt
    30241 catttcagtt ccttctttct ttcatccatt ttaccacttt ttataggaga aggatagtgg
    30301 gaaggtggat ttctaagtta gtatcttagt cctgctctat cttagaaaag gatagtattc
    30361 tcttgcatgt agtgcaaaat ctagtaaaca ttccaaaatt aactcgaata tttatttcca
    30421 aacaaaaaaa caatacacca tcaaagttgt ttaggttttt catgaaattt acagaaaata
    30481 gttgacttcc ctttcttctt tctttaaata tatagttggt tgagtttgga atagtacgct
    30541 gtagctgcta aaacatttct agaaattaat ttgactttcc taatagagtt gttcatatct
    30601 tatttcaatt tactatagta caaaactaga aaaggaaaaa atcatgacca aaacaattct
    30661 tgttacaggt gggactagct acattggctc ccataccgtt aaagctcttt taaatgctgg
    30721 ttataaggtg catgtcctcg ataatctctc cacaggaaat cgagcggctg tgggtagtcg
    30781 tgctagcttt aaagaactgg atgtttatga tgctagcgcc ttaaaggctt acttagaaga
    30841 aaatcagatt gatgctgtcc tccattatgc aggtgaaatt gttgtgagcg aaagtattga
    30901 aaatccaagt aaatacttca ctgccaacgt tgctggtatg gaccaagttc tcaaagtctt
    30961 atctgaagtt ggcattcaaa aaatcatgtt ctcttcgact gtttctctct atggaaataa
    31021 ctgtattgac aagccggtga ctgaagatac cctgctcgac cctgtcaacc cttatgcaga
    31081 gacaaaactg atgggcgaac gaatgattta ctggatggcc aatcgctacg actggaaata
    31141 tgttattttc cgttacttta atgttgctgg ggctgaaatg gatgcttcaa acggtctgcg
    31201 tgtgaaaaat ccaactcaca tcattccaaa tatcaacaag accgcattgg gacaaaatga
    31261 tagcttaaaa atatttggag atgactacga tacacgtgac ggttcatgta ttcgagatta
    31321 catttatgtc ttggaccttg cataggctca tgttaaagga atgaactacc tatttcaaga
    31381 agacagttct tctcaaatct ttaacttagg aactaaaaaa ggctatacta tcaaagaaat
    31441 ctttaaaact gctgaagaat tactaaatta aaaaatccca cacgagattg ttgctcgacg
    31501 tgctagtgac ccagccagtg tcctagcaga tgcttcaaaa gctaaacaat atcttgattg
    31561 gacggctagc tactccctcg aagatattat tttatcagat taaggtaaaa acattttaga
    31621 ataggataac aaaggagaaa gtcttgttgc tctctccttg ttgtatttat taaattgtca
    31681 gaaattttat tgacagatta gaaaaataat gttacattta tatccgcagg tatctttcga
    31741 taccaaatct acatgaaagg acggggtatg aaactttctc attatttaat tggcttactt
    31801 ctactcctag tctttctctc tattagcatt gggaccagtg atttttcatg gggaaagcta
    31861 tttgatttcg accagcagac ctggctcctc tttcaagagt cccgtctccc aagaactatc
    31921 agtattctcc tgactgcctc tagtatgagt atggcaggcc ttctcatgca gactattacc
    31981 caaaatcagt ttgctgcacc gagtacagtt ggaacgactg aagccgccaa actgggaatg
    32041 gtgctgagcc tttttgtctt tccatcggct agtctgaccc aaaagatgct cttcgctttt
    32101 gtttcatcca tcgtattcac cctcttcttc ctagccttta tgaccatttt tactgtaaag
    32161 gaaaggtgga tgttgcctct gattgggatc atctatagcg ggattatcgg ctcagtcaca
    32221 gaagttatcg cctatcgttt caatctggtt cagagtatga ctgcctggac ccagggctcc
    32281 ttctccatga ttcagaccca tcagtatgag tggctcttct taggcctcat catcctgata
    32341 accgtttgga aattatccca aaccttcacc atcatgaatc tagggaaaga aaccagcgag
    32401 agtttgggga tttcctactc cctacttgaa aaactggccc tctttctggt ggcgctaacg
    32461 acaagcgtca ccatgattac cgtgggtggc ttaccatttc tcggagttat cgttcccaat
    32521 cttgttcgca agcgctatgg agataatcta agtcaaacca aactcatggt cgcactggtt
    32581 ggtgccaatc tagttctggc ttgcgatatc ctatcccgag ttctgattag accctatgag
    32641 ttgtctgtca gtctcttgct aggaatcatc ggtagtctcg tctttatcct acttctctgg
    32701 agagggggac gaaaagatgc agactaaaag caaacatacc aagctcttct ggattctcat
    32761 tattcttgcc atcggagctt gtcttctcta cttttggccc atcactcact tgtcagcctt
    32821 tgcttggaag ttgcgttccc aaaagatcat cgtttatctc ttggtagcca tcgcgactgg
    32881 gatttcgacc attagttttc aaaccctgac ggaaaatcgc ttcctgacgc ctagtatttt
    32941 gggaattgaa tccttctacg tcctactaca aaccctacta ctggtttttg aaagcaagtt
    33001 tcttcaactt ggcaaatccc ctatcttaga attcctagtc ttacttcttg tccagtccct
    33061 cttctttctc gccttacaag gttacttgaa gacactgatg aagcaagacc tggtcttcat
    33121 cctgctgatc tgtctagcgc tcagaagtct ctttcgaaat atcagcacct tccttcaagt
    33181 cctaatggat ccaaacgaat acgataaact gcaaaatagt ctttttgcct cctttcaaca
    33241 tctcaacact tccatcctag ccatcggttc tctgatcatc ctcgctttga caatcttttt
    33301 ctttcgaaaa gcagtcgttc tagatgtctt gcacctgcaa agagaaacgg ctcagatatt
    33361 gggactcgat gttgaaaaag aacagaaaga gctcctctgg ggaatcgtgc ttttgacctc
    33421 aacggccact gccttggtag gacctatggc cttcttcggc tttatgctgg ccaacctcac
    33481 ctacctgatt gtcaaagact atcagcacaa gttactcttt atagtggcca ttctggttgg
    33541 atttattagc ttaaccttgg ggcaagcctt gattgaacga gtctttgcac tggaaattcg
    33601 tatcagtatg atcattgaga gtgtgggtgg cttcttattc tttatcttac tatataggag
    33661 gtctcgtcag tgaaactgga aaacattgac aaatccattc aaaaacagga tattttgcaa
    33721 ggcatttcgc ttgaagtcag tcctcaaaaa ctgacagcct ttattggtcc aaatggtgct
    33781 ggaaaatcga ctctcctctc catcatgagc agactaacca agaaagatca gggagttctc
    33841 agtatcaaag gacgtgaaat cgagagctgg aattcgcaag aactggccca agaactaacc
    33901 atcctaaaac agaaaatcaa ttaccaagcc aaattgactg ttgaagaact ggtcagtttt
    33961 ggacgttttc cctacagccg aggtcgactt agatcagaag actgggaaaa aatccgagaa
    34021 actctgaact atttggaact gaccaactta aaagaccgct acatcaatag cctgtcaggg
    34081 gggcaactcc agcgcgtctt tatcgctatg gtactggccc aggatacgga ctttatcttg
    34141 ctggacgaac cactcaacaa tctcgatatc aagcaaagcg tcagcatgat gcagattctt
    34201 cgacgactgg tggaggaact cggcaagacc attatcatcg tcctccacga tatcaacatg
    34261 gccagtcagt atgcagatga aattgtcgcc ttcaaggacg gccaggtctt tagcaaggga
    34321 agaaccgatc aaatcatgca ggctgacctg ctcagtcaac tttatgagat tcccatcacg
    34381 ctagctgata tcaataacaa aaagatctgt atctatagct agtaacataa aagctcaagt
    34441 tagagaacct tcagtctctt agtcaataag attaagagac tccctaaatc gttatcacat
    34501 tttaaaaagg agaaattatg aaaacatccc ttaaacttta tttcactgcc ctagtggcca
    34561 gcttcttgct cctacttggt gcatgtagta caaactcaag cactagtcag acagagacca
    34621 gtagctctgc tccaacagag ataaccatta aaagttcact ggacgaggtc aaactttcca
    34681 aagttcctga aaagattgtg acctttgacc tcggcgctgc agatactatt cgcgctttag
    34741 gatttgaaaa aaatatcgtc ggaatgccta caaaaactgt tccgacttat ctaaaagacc
    34801 tagtgggaac tgtcaaaaat gttggttcta tgaaagaacc tgatttagaa gctatcgccg
    34861 cccttgagcc tgatttgatt atcgcttcac cacgtacaca aaaattcgta gacaaattca
    34921 aagaaatcgc cccaaccgtt ctcttccaag caagcaagga tgactactgg acttctacca
    34981 aggctaatat cgaatcctta gcaagtgcct tcggcgaaac tagtacacaa aaagccaagg
    35041 aagaattggc caagctagac aagagcatcc aagaagtcgc tactaaaaat gaaagctctg
    35101 acaaaaaagc ccttgcgatc ctccttaatg aaggaaaaat ggcagccttt ggtgccaaat
    35161 ctcgtttctc tttcttgtac caaaccttga aattcaaacc aactgataca aaatttgaag
    35221 actcacgcca cggacaagaa gtcagctttg aaagtgtcaa agaaatcaac cctgacatcc
    35281 tctttgtcat caaccgtacc cttgccatcg gtggggacaa ctctagcaac gacggtgtcc
    35341 tagaaaatgc ccttatcgct gaaacacctg ctgctaaaaa tggtaagatt atccaactaa
    35401 caccagacct ctggtatcta agcggaggcg gacttgaatc aacaaaactc atgattgaag
    35461 acatacaaaa agctttgaaa taagccactt caaactcaat ttaatactca atgaaaatca
    35521 aagagcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgag gttgcagatg
    35581 aaagctgacg cggtttgaag ggattttcga agagtataaa attttgacat tctaaaacgc
    35641 atcctatcaa gttcactcaa acctgatagg atgcgttttt atcattttga aatctattta
    35701 ccccacctca ttccccttct tgatttcgtt taagggaaaa gtggtctgga acggggtcct
    35761 tacctgtttt cgaccaggga tgacaacgta aaatccgagc caagcccatc aatactccct
    35821 taaaaccatg tttttcaata gcctgaatca tgtagttgga acaagtcaga tcaaagcgac
    35881 aagagggtgg aaagactggt gagataaaac gttggtaaaa gcgcacaggc gctattaaaa
    35941 ttcgtttcat tatttcttag ttacagccat ggtgtgtagt tggctgattt cttttttatt
    36001 aagacgacgg gattctcctg gacggagtcc tgtcaagtct aggtgtccga aacgagtccg
    36061 agacaactta tctacttgga gaccaacagc ttcaaacatc tttttaacct gatggttacg
    36121 cccttcatgg atggtcaact gcaccacaga gcgatttttg actgggtcca ctttgagaat
    36181 ttcataaaca gctggcttgg ttttcttacc atcaatctca agaccacggg tcaaggggcg
    36241 aagattgtcc ttattggcca cacctttaac acgcgcgaca taaaccttgt caatctcatt
    36301 acgagggtga atcatctcgt ctgtaaagtc cccatcatta gtcaaaatca agacacctga
    36361 tgtatcccag tccaaacgac ccacagggta aatacgttct ttgacattgg gcaagaggtc
    36421 gacaaccgtc ttgcgaccct tatcatctgt cacactggaa atcacaccgc gtggtttgtt
    36481 aagcagatag tagacctttt cttcgttgta gataggttga ccttcaactt cgaccttgtc
    36541 gcctgacttg atagtggttg ctagttcacg caccacttgg ccgttaaccg tcaccaaacc
    36601 ttgcttgatc agctcttctg cttttctcct actggccaca cctgcgtggg caatatactt
    36661 attgattctc atcttcttct atcctttcac caaataattg gctttcttgg gcttgaatct
    36721 caagctcatc aatcactggt aattcttcta aatggtttat ccccatgtaa tctaggaaat
    36781 aatccgtagt cacatagagg ttggggcgcc ccaatacttc ctttttcccg tcttccttta
    36841 tcaggtcaaa agcctgcaac tttgccaagg ctccactcga gttaacccca cggatggcat
    36901 caatttctat ccgcgtaatc ggctgtttgt aggcaataat ggacaaggtc tcaagggcag
    36961 cccgagacaa gctctggttg ataggcgcct tagagtattc cttcaaaatc tctgcaaatt
    37021 gaggcttggt caccaatcta taagcaccac ttgtctcaat caaagccaaa ctggaatctg
    37081 ggtccttttc atacttctgg gctaattttc ctaaactttg ctggatgcct gtcggtggca
    37141 gagagaggag ttcagctaac tggcggaccc gaatcccatc ttcacccgct acaaacaaga
    37201 gcgcttctat ttttgctaaa gtactcatct ttcctctcta tcaagtctag ctttgaggca
    37261 cttgactttc ttccttcttt tccatgagat agatatctcc aaaactctcc tcttgcacga
    37321 ggatcagctc ctgggttttg attaactcta gggttgccaa aaagagggtg atgacctctt
    37381 ggacattctg ggcttccttg aacaaatcct gcaagcgcaa ttgatctcgt ccaatcaagg
    37441 actctttcac gataatcatc atgtcctcaa tcttatactc atcccgcaag atcgtcgtgt
    37501 gattttgtgc aaactcctct tttttcttgg ctaggatatt tgaaaaagcc aaaaagaggt
    37561 caatggtcgt cttgtcatgc acaagctccg catcttcgta aatcaactct gtcggcgctt
    37621 tggaataata ctgggcccgt tcttggtgct tggcttccaa gtgctcaccc aagagcttga
    37681 acttgcgata ttcttcgatt tgagagagga ggtcctgctc caggtcatcc cccaagtctg
    37741 tcacttctgc taccttcgga aggagtttac gactcttaat cagcatgagc tgactagcca
    37801 tgaccatgta ctcacccgtc acttccagac gcatggcctg cagggttgag acataggcta
    37861 gatactgttc gatgacttcc gtaatgggca catcgtagat atccatctgg tacttagaaa
    37921 ccagatgcaa gagcaagtcc aggggtcctt caaaatcttt taatttaata tccattatct
    37981 atatttttct aaggtcagga ctgtttttaa tcctaatttt tttgcaattt cgtacaaatc
    38041 gaccttgttt tctatttgtc ttagaataaa ctgttcacgt aagacttgag ctgataagga
    38101 tggaaaacct ttctccttga caaaagattc taactgacga aaggcccact gacgagaata
    38161 gggtttctct cctctttcaa aaagataggt ctgccccatc aagggttcca attctgaaag
    38221 caaggccgtg ggaatggtga caatcctctg ttgggaagcc ttgctgattc gcaacacctg
    38281 aaaatccaga ttgatgtccg caaccttgat ggctaaaatc tcactgggca agagccccat
    38341 ttctaggatt aagagcgcta gcaagcggcc ctctggatgg tcgctttcct gccaaaaaga
    38401 gtctaggtat agaatctctg gcttttccgt cttcttttca gcttgtttgg ctaattccaa
    38461 gcggtaaaag ctgtccacct ctcctttttg atagagaaag tatagaaatt ggttacaggc
    38521 cgaaatcttt cgcttctgga cgctgatttt tagattggct agctgggctt ggtaaatctt
    38581 gagactggtc tcagaaatcc gctcacctac catgtctaaa aattgctcca aatcatactt
    38641 ataggactgc ttggaattga cagacaagcc ctgcttttcc tctaaaaagg ctgaaatcct
    38701 gtctctcatt ggcatcgaat ctcatattcc ttactaaagt catgcaagag ggcattaacg
    38761 gccttgagga tggacttgcg cgtaataatc ccttggaaaa taccctctgc atccacaacc
    38821 ggtaagaagg actcatctac tagcttgtgc aagacctccg taatggtgaa atcaggcgaa
    38881 acaaccgcta cgtccgtttt tgtcatatga acgatatccg tatccgccat gatttcttgg
    38941 ctcaagtcat gctccatctg ataagccata atatctctga gtccaatcgt cccaacaaac
    39001 tgtttttcat ctgtcacaac gggaacacgg gtataggtca tctgactgag caagagggtc
    39061 gcatgatccg cattgtgggt atcaatcaac acagctagat ttttagcagg ggtcaaaaaa
    39121 gtttcctcct gccccaacaa gaaagtctca aactccttgg caatcatcgg ctaaactcct
    39181 tggacaaacc tggatacacc tcgtgatctc gtgtcaaaaa gtccactttg aagtaactat
    39241 catcaatctc cacacgagca tagagacatt ctctgatggt acctcgtggt tgactgatag
    39301 aacctggatt tagaaagagg atcttgcctt ccaaccaagc acttggcaca tgcaagtgac
    39361 catagaggca gatagcggcc tcttcctcct gagcccagta gtccaacttt tgaaagttga
    39421 aattgatgtc aaacaagtga ccatgagttt ggataatctt ggtcgaacca agctcagtca
    39481 ccagacgttc tgggtagccg gcgtagaagt ccatgttccc tttaacaacg cggatgccct
    39541 cccaaagtgg agaatccgga cgtagttcag aatcgccgtt atgaaaaacg gcatcgactt
    39601 tgcccacata gcgatcacgg acttcttcca caatcaagct atcgccatgg gaatcgctca
    39661 ttacaatgat ggtttgcttt gccatgatgg aaatacctcc aaaagtttct taacggctaa
    39721 ggcacggtga gattgactat ttttttcttc cagggttaat tcagctgatg actcacctgt
    39781 ttctcctaca aggaagaggg gatcatagcc aaagccattt tcacccttag gttcaaagtt
    39841 aatataacct gaccagtctg cttcaacaac taaactttcc ttatttgggc tggctacgac
    39901 tagggttgtg tggaactgag ccgagcggtc cttgagttca aagaccatgg ccaattcgtg
    39961 caagagtttg gcattatttt cacggtcagt tgctcccaca cctgcgaaac gagctgacca
    40021 gacgcctggt aagccaccaa ggacatcgac tttgagacca gaatcatctg ccaaaaccat
    40081 cttgcccgtt aattgagaaa tggtttctgc cttaaggcgg gcattttctt caaaggtcat
    40141 acctgtttct gctacttcag gcaggtcagg gtagtcatta agattttcca catcgtagcc
    40201 taacttatca aagatagctc ggaattcctt ggttttacct tcgttacgag tcgcaatcaa
    40261 caaggtttct ctgaccttgc ttgtctcaaa gaaatcatga acattgaccc cttctttagg
    40321 caattctaca tacaagagtt gcccattttc aaccaagagc agggccccat gacgttgaat
    40381 aacttccaag tttcgtccca tttcttgatt aagcatgtct accacaaagg agaacaaacg
    40441 gtaggtagaa ccatagcgta aaacagtaac tgaaagcggg aaaccatact cttcatctcc
    40501 aaatattttg gagaattcaa acagaggaaa atctgtctta tagtcgctca aactgttaac
    40561 gccaccaaaa atactataag acccaacata ccagtcctgg tcatccttat attcataaat
    40621 tttatttgtc ataattctac atgctccaca tgaatctctt tttccagcca ttcttcacca
    40681 atttgtgcaa aactttggct actggctgtt gtgtaaaaac ggtgatggag tggtccagca
    40741 tcgcgaccac gattgatttc aaaataattg agtaagactg agatatcccg tacgcactct
    40801 gccccactat cgatgagctg aacctttggc cccatcacat tttggataat agggcgaagg
    40861 agtggataat gagtacagcc caaaatcagg ctatccacct ttccaaccaa gggacgcagg
    40921 gtttcataga ccaccttctt ggtaacactg gttgacaggg cacctgactc aaccaaggga
    40981 gcaaacttgg gacaggccaa gctctccacc tgtaagtcgg gatccagatc atggattttc
    41041 tgacggtata tgtctgattg taccgtcatg ggcgttccaa tcactccgat tttcccacct
    41101 tgactggact tgatggctgc cgaagctcct ggcaaaatta cacccaagac aggaatatct
    41161 agttgagcct tgatttcttc ccagacgacc gcagtcgcag tgttacaagc aatgacaatc
    41221 attttgacat ccttggtcaa gagaaagttg accagctgcc aagtatattc acgaatttgc
    41281 tcagcaggac gggggccata gggcgcccgc gccgaatctc caatatagac gatttcttca
    41341 tggggaagct ggcgcatgag ctcgcgcaca acggtcaagc ccccgacacc cgaatccaaa
    41401 aaaccaattg gtcgattatc catacagtct tctttctagt cttttttctg attgatcgtt
    41461 cattatgatt ccttgtactg aacgaactga ccgacagctt gatagaatgt caactacctc
    41521 tctcttaatc ataatcaaat atcaatagaa tgcaaggaaa aagtctcatc cctaaaccat
    41581 aaccaacata gtgagaagtc tggaactttc atcccagact tttccttatt tattttttct
    41641 ttttattgtt agcaagggct gccttttgtt ggcggatgat ttggtggtaa acttgttgta
    41701 ccttagcttc gcttggtttt tgaccatttg cactcaaaag agtacgaact gcttcagcat
    41761 tcaaacgtgg gttgtcagca aattcttttt cgatttgctt acgaaccaag tacattcctc
    41821 caagagctcc tcctagaaaa gctagcacaa tcaatacaat tgctaaaagt aaatccatca
    41881 tttttctcct gtttcttttt gagtcccttt cattatacca caaactagcc accctgacca
    41941 gtttgttcta cactttcaag gatggaatag acagcaaaaa gaaccctgct tttctgaaaa
    42001 agaggtctcc ttgctaagtt taatttacat aaatagccag tgtttgatag ggttttagta
    42061 gaattttctc agacacttct gcatcttcat agtttgaaat caaaatctgt ccattttggt
    42121 agactgctgg caagtcgatt tccacttctt tagcataaaa gttattgagc actagtaact
    42181 tttgatcctc aaactggcgt tcaaaagcgt agacttgttt gctatcttca aaggctggtt
    42241 tgtaacttcc ttctgaaatg attggcattt ccttacgcag tcgaatcaag tcttgataga
    42301 aggtaaaaat cggaccctgg atttcatttt ctacattgat gtctttatag gatttaccag
    42361 ctttcaacca aggagtgcct gttgaaaatc ctgcattttc cgaagcatcc cactgcatgg
    42421 gaatgcgtga attatcacgc gacttagctt gaataatctg gaaggcttct tgctgactct
    42481 ttccttcttc taggagcatc tgataggcat taagcgattc gacatccacg taatcagcca
    42541 tagaatcata gtctgggtca atcatcccga tttcctcacc catgtagata taaggtgtcc
    42601 cacgtgacag gtgaatgctg gctgctagca tagtggctcc ttccttgcgg aagttttgaa
    42661 tatcgacaaa acggttcaag gcacgtggtt gatcgtgatt gttccaaaag agggcactcc
    42721 aaccgtcttt atcactcatt tccttacccc aactatggta aagactcttc aactcttcaa
    42781 aatcaaaggg agccaaggtc cacttttgtc catccttata gtccaccttg aggtgatgaa
    42841 aattaaaggt catggataat tcctgacgat caggcgacga atagaggaca cagttttcca
    42901 tggtggtaga agacatttcc ccaactgtca taaagctatc gtcagatcca aaagtggctt
    42961 ggttcatcat acgcaaatag ttatgaacga tgggtttgtc tgtataagct ggcttccctt
    43021 cattttcagg acagtccact gaaacctcgt ccttaccgat caaattgatc acatcaaatc
    43081 gaaaaccttt gacacccttg tcgcgccaga aattaacaac cttgaaaagc tccttacgga
    43141 cattgggatt gcgccagtta aggtcagcct gggtctcatc aaataggtga agatagtatt
    43201 tcccagtatc cccgaaaggc gcccatgcag aaccaccaaa cttagactgc caatctgttg
    43261 gttggtcttg gatgaagaaa aagtcttgat aatacttatc accagctagg gctttctgaa
    43321 accattcatg ctctgtcgaa caatgattaa gtaccatgtc cagcataaag tcaatcttgt
    43381 gctctttacc gacacacacc atttcctcaa aatcagccat atcaccaaaa agaggatcca
    43441 ctgccatata atctgaaata tcgtaaccat tatcccgttg agggcttgga tagaatggat
    43501 tgagccagac catatccaca cctagtttgg ctaaataggg aattttttcg ataatcccac
    43561 ggaaatcccc aataccgttt tcagtggtgt ctttgtaaga ttttggatag atttgataga
    43621 ctacttttcc tttatcaagt gtcatctgtt tctccttttc tgataaaagg gaggaagcag
    43681 tcttccgtcc ctatttgtgc tatttcaatt atactcaatg aaaatcaaag aacaaactag
    43741 gaagctagcc acaggttgct caaaacacta ttttgaggtt gcagatagag ctgacgtggt
    43801 ttgaagagat tttcgaagag tattagattc gtgtagcgac catgagagat gctccagctt
    43861 ggatcgttgt cggataagtt ccagtaatag tcgctgtata agcatcttgg ttggtgatga
    43921 taacaggagt ttctgtcacc agacctgcag ccttaatgac atccatatca aaacgaatca
    43981 gttgctggcc aactataacg tgatctcctt ggactacaag actttcaaaa cctttgccat
    44041 caagacctac tgtatccata ccgatgtgga tgagcaattc aactccctcg tcagagacaa
    44101 tgccgatggc atgcttggta gggaaaagaa ccgtcactgt tccattaact ggagaggtca
    44161 actcaccttg gcttggttca atgaccagac cttgccccat gacacctgat gcaaaaacag
    44221 gatccgtcgc ttgactcaat tctttcactt ggccagttag tgggctgata atttctaccg
    44281 aagtaagttc tactggttca tggctcacaa attctgcttc ttcttgagca acgaattctg
    44341 cctgcaagtt cgtatcgccc tctatttttg tgaagagacc agccttgcga aagaagaaag
    44401 tcaagagcat tggaacaaca atcgcaacta gcatagttcc tgcaaatggc agcatgtatt
    44461 gaggttgaat agagagaata cctggcaaac caccgatacc aatagaagcc gcagttacat
    44521 taaaagtaac ggataacatg cctgcaaggg ctgaaccagt catcccagca acaaatggat
    44581 aaatatattt tacgttaacc ccaaaaagag ctggttctgt aacaccgaga taggctgaaa
    44641 tggttgcagg aagtgaaacc tgagcctcac gctcatcatg gcgatgcatg aaataatagg
    44701 caaacacggc tgagccttga gcaatattag aaagagcaat cataggccag agggcagtgc
    44761 caccagcatc cgcaatcaat tgtgtatcaa tggcattggt catgtggtgc agacctgtga
    44821 tgacaaatgg agcgtagagg gcaccaaaaa ttgcaccgaa gagccatttt acaggacccg
    44881 ttaaacctgc caatacaact gatgaaagtc cttgtccaat tgtccaaccg attggcccca
    44941 agacagtatg agccaaaatc aaggctggaa tcaatgacaa aaaaggtaca aaaatcatgg
    45001 aaatgacttc tgggatatgt ttgcgccaaa aaatttcaag ataagacaga ctcaaacctg
    45061 caagcaaggc tgggataact tgggcttggt aaccaatacg attaacagta aaataaccaa
    45121 aattccaaac ccagtttgct gcgatatcag ctgctggcgt tgaagcaacc gcataggcat
    45181 tgagcaactg aggcgatacc aaacagattc cgagaacaat tcccaaaatt tggctggttc
    45241 ccatcttacg agaaacagac caagtaatcc ctactggtaa gaactggaag atagcttcac
    45301 caggcaacca gaggaagtga ttgacacctg cccaaaactg agaggattct gtgatggtct
    45361 tgccatccaa catcgaccaa tggacacctt ccaagacatt acggaaaccg aggatcaatc
    45421 ctccgactat caaggctgga ataatcggag taaaaatctc cgccagagtg gtcataacac
    45481 gttggaccac gttttgatta ctcttagctg cagacttggc tgcttctttg gaaacaccct
    45541 caatacctga aacggctgta aaatcattat aaaagatggg cacgtcattt ccaatgatta
    45601 cctgaaattg acctgcattt gtaaaagttc ctttaacagc tggaattgac tcgatagctt
    45661 taacattagc cttcttatca tctcctaaaa caaagcgcat ccgtgtcgca cagtgagtta
    45721 cggcagtcac attttctttg cctccaattg cctgaagcag atctttggct tcttgttcaa
    45781 attttcccat ttgattctcc ttatacttgt caaagcaagt ttgatttgat aagtatattg
    45841 taaacgatac caaacttgtc tgcaacttgt ttggtataaa aagggtgttt ttttgtaaat
    45901 tttctagcac ttgtatggta aaatagatac aggtgttcat taaactagac taaaaaccta
    45961 tttaagcagg caaaatgaag aaataccaac aattatttaa gcaaatccaa gaaaccattc
    46021 aaaacgagac ttacgctgtc ggagatttcc ttcctagcga gcacgacctt atggagcaat
    46081 atcaagtgag tcgtgatacc gtccgaaagg ccctgtctct cctccaagag gaaggattga
    46141 tcaaaaagat aagagggcaa ggttctcaag tcgtcaaaga agaaaccgtc aatttccctg
    46201 tatccaacct aaccagctac caagaactag ttaaagaact tggactgcgc tctaaaacca
    46261 acgtggtcag tctggacaag attattattg ataaaaaatc ctcactgata accggtttcc
    46321 cagagtttcg gatggtttgg aaggtggtcc gccagcgtgt ggtggatgat ctggtatccg
    46381 ttctggatac ggactatctg gatatggaac taattccaaa tctcactcgc caaattgctg
    46441 agcagtctat ctattcttat atagaaaatg gcctcaaact ccttattgat tatgctcaga
    46501 aggaaatcac cattgaccac tcaagcgacc gagacaagat tctcatggac attggcaaag
    46561 acccttatgt cgtttcgatt aaatcaaaag tctatctcca agacggacgc caatttcagt
    46621 ttaccgaaag tcgccataag ttagagaaat ttagatttgt agattttgca aaacgcaaga
    46681 aataaaagac tgagacacca gatctcagcc tttttcggct ctataatatt tgtagtgggt
    46741 aaccccccta tggatattat ggagcctatt tt
//
LOCUS       DAVMBH010000010        46445 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVMBH010000010 DAVMBH010000000
VERSION     DAVMBH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.010"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(491..2218)
                     /gene="ezrA"
                     /locus_tag="VYP30_000678"
     CDS             complement(491..2218)
                     /gene="ezrA"
                     /locus_tag="VYP30_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1807714.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2300..4246)
                     /gene="gyrB"
                     /locus_tag="VYP30_000679"
     CDS             complement(2300..4246)
                     /gene="gyrB"
                     /locus_tag="VYP30_000679"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1807715.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4261..4824)
                     /locus_tag="VYP30_000680"
     CDS             complement(4261..4824)
                     /locus_tag="VYP30_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1807716.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4909..5463)
                     /locus_tag="VYP30_000681"
     CDS             complement(4909..5463)
                     /locus_tag="VYP30_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1807717.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5474..6697)
                     /locus_tag="VYP30_000682"
     CDS             complement(5474..6697)
                     /locus_tag="VYP30_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1807718.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6734..9184)
                     /locus_tag="VYP30_000683"
     CDS             complement(6734..9184)
                     /locus_tag="VYP30_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1807719.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLRKKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTEASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEDFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9384..10313)
                     /locus_tag="VYP30_000684"
     CDS             complement(9384..10313)
                     /locus_tag="VYP30_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1807720.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     AQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            10453..10740
                     /locus_tag="VYP30_000685"
     CDS             10453..10740
                     /locus_tag="VYP30_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1807721.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10774..12108)
                     /gene="ciaH"
                     /locus_tag="VYP30_000686"
     CDS             complement(10774..12108)
                     /gene="ciaH"
                     /locus_tag="VYP30_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1807722.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12098..12772)
                     /gene="ciaR"
                     /locus_tag="VYP30_000687"
     CDS             complement(12098..12772)
                     /gene="ciaR"
                     /locus_tag="VYP30_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1807723.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12881..15427)
                     /locus_tag="VYP30_000688"
     CDS             complement(12881..15427)
                     /locus_tag="VYP30_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1807724.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15550..15990)
                     /locus_tag="VYP30_000689"
     CDS             complement(15550..15990)
                     /locus_tag="VYP30_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1807725.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCVVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15965..16834)
                     /locus_tag="VYP30_000690"
     CDS             complement(15965..16834)
                     /locus_tag="VYP30_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1807726.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLDTICSFYLDKEVWYRFSELTNTEANCLAGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAESHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16876..17604)
                     /locus_tag="VYP30_000691"
     CDS             complement(16876..17604)
                     /locus_tag="VYP30_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807727.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17612..18091)
                     /locus_tag="VYP30_000692"
     CDS             complement(17612..18091)
                     /locus_tag="VYP30_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1807728.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18102..18800)
                     /locus_tag="VYP30_000693"
     CDS             complement(18102..18800)
                     /locus_tag="VYP30_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1807729.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18793..19059)
                     /locus_tag="VYP30_000694"
     CDS             complement(18793..19059)
                     /locus_tag="VYP30_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1807730.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19127..20053)
                     /locus_tag="VYP30_000695"
     CDS             complement(19127..20053)
                     /locus_tag="VYP30_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1807731.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKYGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20128..20943)
                     /locus_tag="VYP30_000696"
     CDS             complement(20128..20943)
                     /locus_tag="VYP30_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807732.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20947..21267)
                     /locus_tag="VYP30_000697"
     CDS             complement(20947..21267)
                     /locus_tag="VYP30_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1807733.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21474..21554)
                     /locus_tag="VYP30_000698"
                     /pseudo
     CDS             complement(21474..21554)
                     /locus_tag="VYP30_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21598..23595)
                     /gene="metG"
                     /locus_tag="VYP30_000699"
     CDS             complement(21598..23595)
                     /gene="metG"
                     /locus_tag="VYP30_000699"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1807734.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWILAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23719..24978)
                     /locus_tag="VYP30_000700"
     CDS             complement(23719..24978)
                     /locus_tag="VYP30_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1807735.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24980..25681)
                     /locus_tag="VYP30_000701"
     CDS             complement(24980..25681)
                     /locus_tag="VYP30_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807736.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAVYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25665..26864)
                     /locus_tag="VYP30_000702"
     CDS             complement(25665..26864)
                     /locus_tag="VYP30_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1807737.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQVPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27150..28496
                     /gene="gor"
                     /locus_tag="VYP30_000703"
     CDS             27150..28496
                     /gene="gor"
                     /locus_tag="VYP30_000703"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1807738.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28693..29229
                     /locus_tag="VYP30_000704"
     CDS             28693..29229
                     /locus_tag="VYP30_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1807739.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29284..29364
                     /locus_tag="VYP30_000705"
                     /pseudo
     CDS             29284..29364
                     /locus_tag="VYP30_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29433..29648)
                     /locus_tag="VYP30_000706"
     CDS             complement(29433..29648)
                     /locus_tag="VYP30_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1807740.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29746..30066
                     /locus_tag="VYP30_000707"
     CDS             29746..30066
                     /locus_tag="VYP30_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807741.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30096..30434)
                     /locus_tag="VYP30_000708"
     CDS             complement(30096..30434)
                     /locus_tag="VYP30_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807742.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30446..31165)
                     /gene="trmD"
                     /locus_tag="VYP30_000709"
     CDS             complement(30446..31165)
                     /gene="trmD"
                     /locus_tag="VYP30_000709"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1807743.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31155..31673)
                     /gene="rimM"
                     /locus_tag="VYP30_000710"
     CDS             complement(31155..31673)
                     /gene="rimM"
                     /locus_tag="VYP30_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1807744.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31704..32492)
                     /locus_tag="VYP30_000711"
     CDS             complement(31704..32492)
                     /locus_tag="VYP30_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1807745.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYLKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32596..32839)
                     /locus_tag="VYP30_000712"
                     /pseudo
     CDS             complement(32596..32839)
                     /locus_tag="VYP30_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(33069..33308)
                     /locus_tag="VYP30_000713"
     CDS             complement(33069..33308)
                     /locus_tag="VYP30_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1807746.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33328..33600)
                     /gene="rpsP"
                     /locus_tag="VYP30_000714"
     CDS             complement(33328..33600)
                     /gene="rpsP"
                     /locus_tag="VYP30_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1807747.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33795..33995
                     /locus_tag="VYP30_000715"
     CDS             33795..33995
                     /locus_tag="VYP30_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807748.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            34474..34686
                     /locus_tag="VYP30_000716"
     CDS             34474..34686
                     /locus_tag="VYP30_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807749.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34770..35573
                     /locus_tag="VYP30_000717"
     CDS             34770..35573
                     /locus_tag="VYP30_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1807750.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKKGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35629..37170)
                     /locus_tag="VYP30_000718"
     CDS             complement(35629..37170)
                     /locus_tag="VYP30_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1807751.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKILLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37172..37654)
                     /locus_tag="VYP30_000719"
     CDS             complement(37172..37654)
                     /locus_tag="VYP30_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1807752.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(37654..38739)
                     /gene="rlmN"
                     /locus_tag="VYP30_000720"
     CDS             complement(37654..38739)
                     /gene="rlmN"
                     /locus_tag="VYP30_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1807753.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQINLAVS
                     LHALNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKAVAAVNP"
     gene            complement(38760..39290)
                     /locus_tag="VYP30_000721"
     CDS             complement(38760..39290)
                     /locus_tag="VYP30_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1807754.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFALVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(39447..40052)
                     /locus_tag="VYP30_000722"
     CDS             complement(39447..40052)
                     /locus_tag="VYP30_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1807755.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40225..41262)
                     /locus_tag="VYP30_000723"
     CDS             complement(40225..41262)
                     /locus_tag="VYP30_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1807756.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41296..42231)
                     /locus_tag="VYP30_000724"
     CDS             complement(41296..42231)
                     /locus_tag="VYP30_000724"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1807757.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDCITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42784..43974)
                     /locus_tag="VYP30_000725"
     CDS             complement(42784..43974)
                     /locus_tag="VYP30_000725"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1807758.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44189..45532)
                     /locus_tag="VYP30_000726"
     CDS             complement(44189..45532)
                     /locus_tag="VYP30_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1807759.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45912..46424)
                     /locus_tag="VYP30_000727"
     CDS             complement(45912..46424)
                     /locus_tag="VYP30_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1807760.1"
                     /translation="MPAEVLSLLPQSGTYTTSSSVAIAFVPEAPMPVEVAVANGTWTF
                     LGYQEVEEGSNLTFVGKWVFEAKQDPSPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDN
                     NQADRHQSEQPRKPEENPPAQGPAGEKEKQATLPNAGSTAPLSLTGLVTSSLLAGLAV
                     LLLGRKRKDD"
BASE COUNT        13780 a        10149 c         8351 g        14165 t
ORIGIN      
        1 aatagcgaga aatatctatc ctatcttcta gaatgtcttc caaacgagaa aactctcgta
       61 aacaaagagg ttttagaggc ctatttaccg tggactaaag ttgtacaaga aaagtgtaaa
      121 taagaaatct ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag
      181 acttcgttat tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga
      241 ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc aaactaagag cctcaggctg
      301 tacttgagta cggtaaggcg acgctgacgt gatttgaaga gattttcgaa gagtataaaa
      361 cactgttttg aggtggtgga taaatcggct gggcaaaaac tcaatctcag gagaaaatga
      421 agtaaatctc cccacaacta tagaaaaaga tttgattctg ctcctcacac aataaaatct
      481 ttttctttta ttaaaaacga atcgtttcac gtgttttctc atatgaggta acaaagcgat
      541 tggttacacc aggctctgcc acttccaatg cttgagaaat cttgtcaaat gaagcgtgat
      601 aatcaaattc tttttcaaaa atatctaaag cttcgttaaa tgcttcttga atgcgttcat
      661 caaatgagcg atagcggtta gaatattgta agagttgctc tgtcaaagtt gcatattgta
      721 caatattata agtttccgtt tctaaagctt ccatatcatt cgttgcaatt tcaagaactc
      781 gggtaacaga ttcaatgtta atcatttttt gttctaactc aaccattaaa tcctcggtat
      841 tattgcttgc cgtaaagaat aacttcaaga aagtttgtgg aatacctggc agattgcgtt
      901 tttccatgta tcgcttgata gtatggagac gattgacata aacattggcc ttttgacgtg
      961 cattaatatc atctttctca atttgtgtca ggcgctcact aactgaaatt tgctcatctt
     1021 caatatcttt tagttgagtt tgtaaatcct caagattttc ttcaagaact gaataagctt
     1081 gggttggttc ttcttgattt gaagttacct caacaatagc tgcctcaaaa ctctctaatt
     1141 ctgtctgaat acgacgaaca tggcttgcag ctgtctcagg aagtaaatag gtcttgttca
     1201 aacgtgcaat atcttccccc aataaagtat tattctcttt catatgttga agataagttg
     1261 gaagagttgc aagtagattt tccactactt tctgagcagc aatttctcga gtaaaaatat
     1321 catacaaggc attgatttcc tcttgtgcct gtccattctc atattcggca ttatccaatt
     1381 ccaactgacg aatattctct tggtttttct tgaatgcttc ataaagcaag tggaaacgcg
     1441 cttcaatatc cgtttcaaca aaatgataat tagcatcaat tagtttacga taaccggctt
     1501 ccaaatcctg taattgatct ggcaattctg tagaaagcgt cgtaaccaag gctggaacac
     1561 gatccacaat atgacttaag gccaaaatgt gattttctgt attatccaaa atcactgcgg
     1621 cttccacagg gtcacccgat gaattcaagg ttacaaattg tgaaaattca gattggatat
     1681 tttctaattg tttttcaatt tcatccaagg cttgaccata ctgttctgaa ttttcagcaa
     1741 ctctatgctg aagttcctca aataaatcca aagcatgaag aacacgacca ctatttttag
     1801 attcttgctt ctctaagtct gccaaagcat tgcgaattgc cgcaatatct tcttcaatca
     1861 aagtaatttg actctcaatt tggtcaattt gatgactggc cttgagaaaa cgaaatgaat
     1921 ggttatagcc ttctgcttca aagagattat tttcaatatc ggcaaaagag ttgagagata
     1981 aatcgaccca tttttgattc cattcacgga aagccacttg actttgtcca atcaagtgca
     2041 tattttttac agcttctact tcatcattta ctggaagatt gtatagttct tcttttcttt
     2101 cttctagcgc ctctaatctc ccctcgtttc gcttacgtag aaagattgcc actacataag
     2161 ccagaactaa aatgactgca attgcaacca ttaaataaat tagttgtcca ttagacatat
     2221 caaactcctt ttttacttga aacaatcgta acgattatat catatttttt agaccaaggg
     2281 aactacttct ccctattttt tagacatcaa gtgtactata gacagcattt tcttcgataa
     2341 actcacgacg aggctctact cgatccccca tcaacatatc aaagatttta tctgcttctg
     2401 cagcatcatc tacagaaact ctagccatca agcgatgttc gggatccatg gttgtttccc
     2461 acagctgatg atcgtccatt tcacctagcc ccttataacg ctgaatagtc ggtttggtac
     2521 gaccttcact ataacgggct aaagcttctt ggagtttgat ttcttgatct gcacccggct
     2581 ggatatattc tttaatctcg cttccaacct tgacaccata gattggtggt tgggcaatat
     2641 aaacataacc agcttctagg attggtttca tataacgata aatcaaggtt aaaagaaggg
     2701 tacgaatgtg ggctccatcg acatcggcat cggtcatcaa aacgagtttt tggtaacggg
     2761 ctttcgaaac atcaaattct gcgccaaatc ctgttcccat ggctgtgaaa agactacgaa
     2821 tttcttcgtt agctagaatc ttatccatac ttgctttttc aacgttcaaa atcttaccgc
     2881 gaattggaag gatagcctga aactcacggt tacgaccaga tttggctgat ccaccagctg
     2941 agtctccttc gacgatgaag agttctgttt cagcagggtt attagaagaa cagtctgcta
     3001 gtttccctgg aaggttggaa atttccaaac cagatttttt acgtgtgact tcacgcgcac
     3061 gcttggcagc cacacgagcc ttggcagcta aaatcccttt ttccacgata cgtttggcaa
     3121 tctgtggatt ttccatgagg aaatcggaga aggcttcact gaagaggcga ttggtaatct
     3181 tgaccacttc gctatttccc aatttggtct tggtttgtcc ttcaaactgt ggatttgggt
     3241 gtttaactga gataactgca gttaagcctt cgcgaacatc ttcccctgtt aaattatctt
     3301 cattgtcttt cagtaactta ttcttacgag cataatcatt gataacacga gtcagtgccg
     3361 tacggaaacc ttgttcatgc gttccacctt catgggtatg aatattattg gcgaaactca
     3421 tgacattttc atggtaacct gttgtgtact gcatggctac ctcaactgta atatcatcca
     3481 tctcaccgtc tgtatagatt ggtgtatcaa agattacatc cttgttctcg ttgatatatt
     3541 caacgtaact agcaatccca ccttcataat gataatgctt ggtttgttcc aaaccttggc
     3601 gcttatcagt gatagaaatt tgaagaccgc gatttagaaa ggccaactct tgaatccgtt
     3661 tatttaattt atcaaaatca aaggttgttg tttcagtaaa gatttttggg tccggtatga
     3721 agtgaaccgt tgttccagtt ctatctgtat ccccaaccac ctcaaggtct gcaacaacat
     3781 gaccacgacg gtattcttgg taatgaatct taccgttttt atggacatga acgtctaatt
     3841 gagtggaaag ggcattaact actgacgacc ccaccccgtg aagaccacct gaaaccttgt
     3901 atccaccacc gccgaacttt cctccagcat gaaggactgt aaagacggtc tcaacagcag
     3961 gacggcctgt tttttcctga atatcgactg ggataccacg cccatcatcc acaacagtaa
     4021 tcgaatcatc tggctcaata aaaacttgaa tatggctggc aaatcctgcc aaggcctcgt
     4081 caattgagtt atcaacaatt tcccagacta gatggtgaag accttctttt gaggttgatc
     4141 caatgtacat ccctggacgc atacgaacag cctctaagcc ctctaaaact tgaatttgac
     4201 tggcatcata atcctgtgcc tgcagatttt tgatttcttc tgtcatctta ttcctttttc
     4261 ttatatgtct aatacttgtc ttaaattcac gatactggta aacaagtggg tatcaagtcc
     4321 tgcagcttga cctgcttcga tatcaatcgg ccgatcacca atgacaagac cagagctaat
     4381 ctgatacttt tctcttaaat aaagcatgga ttcgggattt ggctttctct taaagcctga
     4441 gctagaagtc accacttctg taaaataagc tgctatagag gttttttcta aaatttccaa
     4501 aacctgatca tttcgatgag agaccaaaaa atgacggcca ccttgatttg aaatgacttc
     4561 caataggtca gaaactcctt caaataaaat cgggtgttca agctctctgg cttcattttc
     4621 cttgtacttt tctaaaaaat tctctaaatt gggagcgaat gtctcaatcg caaaaggagt
     4681 agaaaccttt aaagcttgat agacactgtc atggtcttgt gtgataccat acagtgccaa
     4741 tgtttcaaca aatgcagctg ttgaagtttc ataattatcc agtaaagttc cacctaaatc
     4801 ccagatgtaa tcgtgatatt tcataccctt cattatagca tttttttatg aaaaaagcga
     4861 tgatttccct gagttttcca cataaaaaac gagagaataa ctcccgtttt actgattttt
     4921 accaaagaca tctcgataga gcattcctgt tcgtaaactc tctgcgtccc ctcctagttg
     4981 ctccactaac tcgtaggcaa aggcaagggc tgttgaagga ccccgactgg ttgtcaactg
     5041 accatctacc actactgttt ccttgacgta gtgaccatca aggatttgct cttgaacgcc
     5101 gtcataacaa gtgtatcgct tatttttcaa tatctctgct tgattgaggg caattggtgc
     5161 cgcacaaatg gctgctagtt tcttcccttc ttgctcgaag ctttgcaatt cttgaatcaa
     5221 ggtctgatta tcacgtaaat gtgcagaacc aggcatacct ccaggaagaa caatcatatc
     5281 atagtctgat aaatctccat caaagacatg atctgctctt acttggattg catgcgaacc
     5341 cgttacttgc tcttcaaaac caaccatatc acatgtgata ttggctcgac gcaagacatc
     5401 tacaactgtc aaggcttcaa tttcttcaaa gccctgagct aacataactg ctacttttac
     5461 catgattttc tccttattta atttgtttta atacaacctt tttccgtttg aatgggactt
     5521 ttccgctctt ttcttcagct agattagtct ggtaactcat cgataaaagc aaaccaacac
     5581 caatcagatt actgataata gctgatcccc cttgcgaaat gaaaggcaag ggaatccccg
     5641 tcaaaggaag tagtccagtc acagcaccga tattctcaaa gatgtggaag agcaacatca
     5701 taatcaaacc tgtggaaata taagtgtaga actggttatt tgatttaaga gtaatcttca
     5761 acatacggta aatcaacatg agatagaggg caataaccag gacagagcca ataaagccaa
     5821 aatcttctgc aataaccgta aaaatcatat ctgactctcg aactgggata agcagattcg
     5881 aagcattaaa tccctgacca aataagccac cactcccaat ggcaatctgc ccttgagcct
     5941 gctggtaagt cgttgtttgg gcaaactcaa agggattgag ccaagccaaa atccgattaa
     6001 tttggtaggt cggcattcca atctggtgaa gaaaagctcg tccgtccttg ctaataaaga
     6061 tagctaagaa accagcaact cctgttacag cagtcacaaa tactgggata ataattttcc
     6121 aagaaacccc tgataataaa acgattcctg agaaaatggc tacaaaaacc aaagccgtcc
     6181 ccaagtcact ttgaagtgct aaaagaacta ggactggaat ggtaaagaga atcatccaga
     6241 aaattaacaa aaagtccagc ggaaccgtgc gtctccattc cttatgtttc tttgtaaatt
     6301 ggacaatgac acgagccaac atgaggatat aggatatctt cataaattct gacggttgga
     6361 atagggtaat tccatttatt gatacccagt ttttggcacc cgttgatgca actaagcttg
     6421 gattataaaa tacaatcggc aagatcataa gtcccaagcc taaaatatat agaaaggggg
     6481 tcaccttcca aagaaattct gtattaaaga gcatgaccac aaaaccaatc acaagcccca
     6541 aggcaatcca ggcgacctgc tgccctaaaa tgggcagaat attattggga taatcatgac
     6601 taacggctat atagatagcc accacaccga tgaccagtag aaaaaatact ggcaagagca
     6661 aactataatc gactctagag tcgagagaac gtttcatata tactaacctt atactttcat
     6721 acaatactat ttatcaaagc tcattaaaaa atctatcaat agcctcgtca acttcggatc
     6781 gagagatggt tttaacagtc gcttcttctg ctagagatgc tactatttgt ttgccgtatc
     6841 gttttccgac gattctccta tccaaaataa gagttaagga acgttggtat tcacgtctca
     6901 tacttcttcc caaagcctgt tttaaacgaa taatggccat tggcaattga taatcataaa
     6961 aggcattttt cccttcttga ttcagttctt gattaatctt tttcgtcaag ggttcttgag
     7021 gattttggaa aggaagcctc ggtacaactt gaatcacaga aggatggctt gaaaaatcaa
     7081 ctccctccca gaaacttgct gcaccaagca agatttgttg ttcacctttt tcaaagcgtt
     7141 tctttagctg atgaacatcc ccatttttat actgggccaa gtggctaact gtaagtaaat
     7201 ccgatactgc tagaagcatg tctttagcgg taaagagaac caaaatcggt tgctggaaag
     7261 cttgaatttc cactagtaaa gcagctacct ctctggcata gacttctaag gaggtttctg
     7321 ttaccagagg gaaatctttg accatgacca cttcttgttc ctgttttccc cgagattcaa
     7381 tcttgacaaa tttagcttca ggatagccta aaaggtctgc caaagaaacc ctctgactaa
     7441 tctcaagagt agccgatact cccaagactt ggcaactctc aggaagtaaa gaggacagaa
     7501 gagtacggcc tgattttgta gaagaaatct gaattttctt ttgactcgtt tcagttactt
     7561 caagccagta atcaccttca gctgtaaaat agcgaaccag ctcatcaaag tcttctactt
     7621 ccaattctga aaaatactga tggagattgt ccagagaatc taagatattt ttcctagatt
     7681 tgccagactg aaattgttct atcaagtaga gacactcaaa gcgaatactt tctagtatcc
     7741 gttgttgaac cctgttttct tctcctacta aagccttatc aattaaatcg ataatagatt
     7801 gtatatcgta ggtctcttga agcagatttt ctagagctaa caaaatcttt tggacttcat
     7861 caataatcag taaacggtca ctgacaaatt caggattatc ttcaagtctg gttacgagat
     7921 aggcatgatt agtcactaaa agcttgcaag tctctgccct ttcttgacta cgtttccaaa
     7981 aatcttccgt cacaaataag ctctgggatg ataaattccc atcatgacga aggtctgcta
     8041 gaaaatgttg gtaacggtag agttgcccga tttcatccaa atctcctgtc tctgtctcag
     8101 taagccagac caagacttgc attttaaagc gtctaaataa gcgattttca tcattttcct
     8161 gcaaggaatg ataaaaggca tccaacttca gataattttg tggtcccttt aagctatgaa
     8221 tatctgtatg gaacacttcc ttgaggcgtt taccttcttc ttccatgatt tgattttgaa
     8281 gaatctttgt cggaacacta agaacaattt gtcgctcttt ggattgagat aaagcgggta
     8341 agagatagcc ataggttttc ccaatccctg tcggcgcttg aatcagagag acaggttcat
     8401 ctttcaatag caagccaacc tctttagcaa aactttcttg ttcctccctc acttcaaggt
     8461 tcaacagaga aatattttta gaaaagtctt gagatagttt tcgtggctcc agagaagctt
     8521 ccgttttctt aaaatataga ccttgaactt ggaccaagtc tggagaactc aggatagatt
     8581 ggttgcgata agtttcctca ataaccaggt aggactcata taggagagcg tcagccattt
     8641 ccagcaagcg ttccaagaga cctttaggaa gctgggtcat ctttttccgt aaaaaaagaa
     8701 gtaattctgc tgtagcttgg gcatctgaaa gggctgtgtg tgcgtgttta agaggaattc
     8761 ctaattctcg acacaaaatc ggcaaactat atttttccag ttcagggaaa aagacctggg
     8821 ccaattcgac cgtatcaaca cgagggtttc ttagctcata gccttcaaaa aataaatttt
     8881 ccgccaagag attagcatca aactgaacat tatgggctac aaaaatccca tcctccacca
     8941 agtcaaatat ttttctggca acttgcgaaa aatcaggtgc ttgcgccaga cgttggtctg
     9001 tcaatcctgt cagttctttg atatgagcat ccaagggttc atgtggattg acatccgtcg
     9061 tatagtgatc gacgatttct ccgtcctcaa tcacgacaat tcccacttgg ataattttag
     9121 ccttactacc tgtgctagtt gcctctaaat ccaccacaac atagcgatta ccaatcgttt
     9181 tcattataaa aaattatacc aaaaaaaggg ccatttggca cctgcaaaca taggataatt
     9241 ttcaaactca agaacactac ttttcttaaa aatcccatcg aatagagcat tctagcctgc
     9301 tgatttttgt aaaatagtga agaaatacga aaaattgaga gaagaaatgt ttgcatcttc
     9361 cttctctcaa cgaatcatgt attttatcta accatgtcag gatcgtagtc ataaaatcct
     9421 gtatcaagga aacggttttt agggtgaagt ttacgaactt cttcatccag caagaaggct
     9481 tgagcatgac taaagttgcc ctcttgaatc aagctacgcg cttggataaa gagttttgca
     9541 atctcaacaa agttctgacc aggagtgtag agcccttcta gtttccagcg agtaaagcca
     9601 tgctccacca attctgttaa tttgatcatc aaatcaaggt cattgttggc aaagatatgg
     9661 gtcccatgat tatcttcaaa aatggaatag tggctctctg gatcacttgg ctcagccaag
     9721 aagaggtcac gtttatgcgt cttttcatca tcgatatgtg taaagttata gtagttttgc
     9781 aagagtggac gtttagaatg atggatgacg ctagcaccgt aaaccaaaac ttcagcagga
     9841 atttccaaaa tctctggcat tttgaaaagt tcagctgatg gaatttcacg cgccaaaaca
     9901 gcctcagatg cgccagcctt ttgtccccag aagttaatct gacgactgct agttaccatg
     9961 gttgaagcat cgtagatggt cttaaatgaa taaccatcgc ggttaactac gtaaaagacg
    10021 cctgcatccc caatcgtaat atagtctgtc ttgatttctt ccaagaagtc taagaaaggc
    10081 ttgatacggt ccatcatatc ttggtgcatg agagcattga ccgcaacgat caattcctta
    10141 ccagcatcat gaaccaactt agcgatttca cgtaattggt cataactaaa ggtcgttggc
    10201 agacgaagac caaaatcttt ctcaccgaca tagatacggt ctacgccagc ttcgagtagt
    10261 tgttcaactt gttcaatact ttcagcagtt gctgtaatga caatcttttc cataagaaaa
    10321 attataccac atttctccaa aatcagccat gctttgaaaa tgaaaaggga ctttattctt
    10381 tttgtaacct ttctgtaata attctctgcc gaaaaaatga taaaataggt atgtactgtt
    10441 aaggagagaa tcatgcccgt aagaaaatta caatcctatg aggtagacta tcaagaagaa
    10501 ttaaaccagc agcttcctca ttaccaagct tatacacctg aagcgcaatc tgatgccaat
    10561 ctcaaggaaa tcctattttt tattaatatc gctgtttttt gtatctgtat tgctatcttt
    10621 agttttatct ttttagcatt aaaattatca actgctcttg cctttgccgc agcaatcgga
    10681 ttcagcttac ttgttttaaa agttcaacgg tctattatca aacgaaaacg tagaagataa
    10741 atccaaaata tcgccccaat tggagcgata tttttatttt ttctttttag atggtgtctg
    10801 aatggcaatc ttcacttcaa agattgttcc cttgggttta ttatctttga cagtaacagt
    10861 tccttttaga gcatctacaa tttgcttggc tagggataat cctaaaccaa aaccaccttt
    10921 ttgccgggtt ctagccttgt ctactcgata aaaacggtca aaaattttct ttttatcttc
    10981 tgtcgaaata ccgattccat tatcagaaac aagtaaataa agattgcgat cggtcgccga
    11041 gataagaaaa tcaatttcac catcctcctc agtatacttg acggcattat cgaaaagaat
    11101 ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt gttcgatgga tacgattttc
    11161 aaaacggaag acacgattat tttccgaagc aatcatctca tagtttgtga aagttgtatt
    11221 aaaaaagcta gttggaactt ctgcaagctc cggcttaatc ccatcatctc tccgagctaa
    11281 gttcagcaag cttgtcgtta aaaaacgcat atttcggact tcttccaaac tcgatgcaat
    11341 gctttcgctc acatccataa tggtagcttc tggcttacga aaaagggtct ctaagcgatt
    11401 ttgcaaaact gcgagtggag ttcgtaactc atgactggca ttttccacaa aagactgttg
    11461 cttctgcata ctctcaagca ggggcctaac actgacccta gctagataga gactggcaag
    11521 taaagacaaa atccagaaac tagccatcac gaccacaatc aattgctcat gcttttgact
    11581 agcctgctcc aactgactgg tattaatcaa gacagcagca tacttgatat tggttgaaac
    11641 cgaactaata ttggtctcca tcaaaatcac acgatagatt tcttcctgcc catagctatt
    11701 aaaaacctga atctggtaga tatgtcctag ttctttcttt tctaacttaa tcttatccaa
    11761 gcccaaaaat cgatttccag aaagaagttg agtaaagtct ttatcaaaga gaatgacttc
    11821 cgtattggaa ctgacattag gttttatttc tactttacta gcgtccgccc tagcattttc
    11881 taaatcttta atctcttctg ttgccctatt tatagccagc tgaataactg cttgaggatt
    11941 ttcactcagt ccatgaagct tatcgtccac cgaagtataa agactcgaat gcatgacttg
    12001 taaaataatc agagtcattg tagaaaaaat cagggtgaag acaccgaagt tgcggataaa
    12061 ataactaaag tcatccgcat accatgtttt tttaagttta ctgaacatct tttaaaagat
    12121 acccaacact acgcaaagtt tgcaaattct ctgcaaaagt ggttcccttt aatttcttac
    12181 ggacttttga aacatagact tcgacaaccg aaatcgttgt atcactatca aatccccata
    12241 gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg attttgaagg aaataaacta
    12301 gtaagtcgaa ctctttcccc agcaattcga caggagtatc ttcaacttta acggtattgg
    12361 ttgataaatt aaccacgata ttcccataag tcaaggtgtt ttcattaaac ttccctgaac
    12421 gtttgagaag ggcctgaatc cgcattttaa gttcttctag gtagaaaggt ttggtcagat
    12481 aatcatccgc tcccagttca aatccatgtc ccttgtcatc caaactttcc ttggcagtca
    12541 taatcagaac tggtgtcgta attccctttt cacgcaattc ttttaagact tggaaaccat
    12601 ttttttctgg caacatcaaa tccagcaaaa tcaagtcata gacaccactc tcagcttcgt
    12661 agagaccttc ttctccatca aatacctgca taacatccgc aaaatcgtct aaaaagtcaa
    12721 atactgaatt tgacagacct aggtcatcct caaccaataa gatttttatc atgagaaact
    12781 cctccttatt aaaactatta taccaaattt gccttaaaaa aaactcaact ctctgcattt
    12841 tacatgagat agctgagttt tctttttatt ttaggcttat ttatgcattt ccgtattgaa
    12901 gaacaactgc ttcgactgca gctttttcac ggctaatcaa gtcaacacgt gctgcaattt
    12961 ccttgattcc cataccgatg ttacggctaa gagcaaggtc agaaagttgc ggctcaaaga
    13021 actccttgta ttccgccaag cgttgctgag tcttaaatac atgagcagga aggataacaa
    13081 agctatcaaa gctcatatct cctccaaggg ctgccttaat ccaagcccag ttttcacgcg
    13141 cccaagacca agctgttttc tgagttgctt gatgagctag gaattggtaa taccaagcag
    13201 acaagtcctg tggtttgacc acaaatttgt ccttccaaga agtaatcagg ttttggatat
    13261 tatccgcatc tgtactgtat gcaagagctg ctgccaactg gcgtttaaag acagcatctg
    13321 ttgcgtgagt ataagtatca agataaagtg ctaacaagtc tttagtctca tgatgtttca
    13381 tctcattaat cagaacttgt gagcgaatag ctgctgggag tcctgcaaga ttctccttgt
    13441 gtgttgcgaa gatttggcta gcgacttgac tagcttctgc atcatttgag cgaatcatca
    13501 tcgaaacagc cagctgacga accaattcat cctcatctga ttctccgtct ttagcttcaa
    13561 aaccaagacg gtcatagtta tgacgagcca atttagcaac cagtcctttg aaggctgttt
    13621 cagcatccgt tccttcatca ataaagcgct caagggctga aatcacttga gaaacagctg
    13681 aaaccaccag ataagactct tccttagcaa gtttatcaag aactggaagc aagtctgcat
    13741 aagaaatgtg ccctgcctca gccaacaaac gacgttcttg aacaatttgc agtttgcttg
    13801 tgttatcaag tgtctctagc tcagcaagaa cagcttctaa caagtctcct tgatagtcgg
    13861 taatatagtg ggcagtattt tcagtgttga gacgaagagc tccttcattt tcagcaagaa
    13921 gagctgcgta gccagggatt tcgatacttt cagtttcgag tgtatcaggc aagcctttcc
    13981 agttgctatt gaggggcacc acccagagac ggttcttgtc ttcgttctca ccgatgaaga
    14041 attgtttttg tgaaatcttc aagacatcat tttcaacttt gacagtaaga actgggtaac
    14101 caggctgttc caaccaagaa tccatgaagg ctgcgacatc acgtcctgac gcttgaccaa
    14161 gggcatccca aaggtcacta ccaatggtgt tgctgtattg gtgtttttca aagtaggcgt
    14221 gcaaaccttt agcaaaatca gcatctccta gccaacggcg aagcatgtgc atgagacggc
    14281 ttcctttggc atagacgata gcgccgtcaa agagtgtatt gatttcatct ggatgtttaa
    14341 cttcgacgtg gacagactga acgccatcag tagcgtcacg ttcaagagca agaggtactc
    14401 cacctgtttg gaaatcttca aagatattcc agcttggttc gatggtatcc acacagacgt
    14461 attccatcat attagcgaaa ctttcattga gccaaaggtc atcccaccat ttcatagtca
    14521 cgaggttccc aaaccattgg tgagccaatt catgggccac aacaagggca acttgttgac
    14581 ggctagcaaa tgtagagttc tcatcgacaa ccaagtaaac ttcacggtag gtcacaagac
    14641 cccagttttc catagcacca gctgagaagt caggaagggc gatgtggaga gattgaggaa
    14701 ttggatactt aactccatag taatcttcgt aaaactcgat agagcgaaca gcgatatcca
    14761 gtgagaaatc aagatttgaa agtggatgtg ctttggttga gtagacacct accagggtac
    14821 catttttagt tttagcggtc accccttgca aatcaccagc aacaaaggcc aacaagtaag
    14881 aagacatgcg aggtgttgtc tcaaacttcc agatacctgt ttccttacgg ttttcaacat
    14941 cgatttctgg catgtttgac aaggccaatt caccttctgc ttggtcaaag cgaagagaga
    15001 ggtcaaaagt tgctttggct tcaggctcat ccacacatgg gaaagcttcg cgcgcaaaat
    15061 ggctctcgaa ctgagtagac aagacctcct tcttgactcc atcaactgta taataagaag
    15121 ggtaaatccc tgtcatgttg tctgtaattt taccagaaaa ggcaagaacc aattcaactt
    15181 gaccagcctc agccaattcg atatgaaggg cttcattgtc atggtcaact gtaaatggac
    15241 gagcttgacc tgcaacttct acagaggtga tttccaagtc tttttggtgg agggagatgc
    15301 ggtcactctg tgcttgacca gtgatggtca ctttcccaga aaaagtcttg gtctcacgac
    15361 tcaaatctaa aaataaatca taatgttcag gaacaaattg cttaataaaa tgttcaactg
    15421 cttgcatagt tttctcctat tctaagttta agagctgctg ctcttcttca aacaaactta
    15481 ttatatcata ttttgcttga gaaaaaagga ttggacagcg atttccaaaa ctttcttcct
    15541 tctaatagtc tacagtgggt agaccttgcg aaattcttct aaaacaacct tgctttcaga
    15601 tgtaaaagtc agccctactt cacccaaaca gtctgtgaaa aagtcctcat gaacctggcg
    15661 ccaataggca agtgatttgt ctccctcacc ttccttaaag gcatgttgcg cagaaacttg
    15721 attgaagagt tcaacagaaa cctttgtaat ttcgacaacg cagacagcct gattttgact
    15781 atctaaaatg acatcgaagg tccctacttg gggaagtggt tcgtcttcta gtacatagag
    15841 gtcataggct gatgctgttg ctgtcttttc tcctttaaac accaaatccg ctaaaaggtc
    15901 tggttcaact ccaaaagccc aagcatcgat ttcatctccg atcaaaggat tgatttgctt
    15961 gtatttattc cacatttctt gcggtatcat gggtactcct ttgtaatttt ttactttctt
    16021 cttttatgtg tttaagatga tctggatggt caatctctaa atcaaaaatc tctggaatag
    16081 aactgtagtg gataatgcac ttgataccca actgattcat tttttgtatg aaagaagtat
    16141 tcagatagcc tgctacagca aaattaatct tgttctttct tgctttatcc tgcatatctc
    16201 ttagcatatc taacattatt ggactttcca tatcatgcca ttgactgttt ctcatagtcg
    16261 caaaaacaaa ggaagtcaaa tcattcattc caactacaat ctttgaaatg cccgtttcca
    16321 gtatactaga taagtcaaaa tacgctgacg gtaattcaat catcgttccg actttcccag
    16381 taaagccata ctgacgcaat actgtaatag cttgttttaa ttggtcggca tcattgacaa
    16441 aaggaaaaat aagagacaga ttgggattgg tttgataaac ttctgtaacg acatgtgatt
    16501 cagcctgaaa ttcatccaaa cacgccagta aacgcctggt tcctctatag ccaaacaagg
    16561 gatgcccttc gtcaaaaaac tctctagtcc ccgctaaaca attggcttct gtattcgtta
    16621 attcagaaaa acgataccaa acttccttat ctaagtaaaa ggagcaaata gtatcaagat
    16681 aatcttttac aaattgctga caacttgcta atatgatgtt ttgattaagc tctctcaata
    16741 agtattcccc acgaatcatg ccgacgtggt gaaatagttg aggataaatt ttttcaagaa
    16801 ttttttcgcc actaagggca agttgatttc tcatagccat tcacctcgtc ttaaaagata
    16861 caatatcata tataattata tcaaaatttc ctctagttca aaagcttcat aaggttcaga
    16921 taactcatat cctaaaaatt ctgctacttt tttggaagcc tcattatgag catcccaaag
    16981 tggaaacata tctctattta aactctctag aatcattgca gcaccaagct ttttagcaaa
    17041 tccatttcct tgttcgtttg gtctagttgc aacttccact tcaactgctt tacggtaaac
    17101 taaccctgag gaaatcccag caatcagttc attattttta agaatcacaa agccaaatcc
    17161 accttttaaa acaaaatcct gataggactc aaaatccccc tgtaaatcct gtgaccattc
    17221 ttccgtagaa aagcagttat aaatatgatt atcaataggc acaatattgt aaccttcctc
    17281 taaatgagta actagattat ttaaaaattc aacttgaaaa tttgccttat ctttaaaaga
    17341 atagcgagta aaagaattta gccccacttt tcgatgcaga aaatcttgcc aattagtatt
    17401 ttctgaaata ataatcttat aatctaaacc atattttcta acaaaatctt cccaaaatct
    17461 ggaatccaac tcccctgcta ggtatagaaa attcccaaca tcataaaagc ttgttgtcct
    17521 atcattgttt cggtagacag ttccaatttg agatttaaga ccatagagaa ccatattttt
    17581 cttccatgtt ttaaatagtt ccattatccc tctacttcac cttccaattc atgtaagaag
    17641 tcttgtccag ttctggaaat cctaataatt cagacttaac cttcaagact aatggcgatg
    17701 cattttcttc tgtaatctct tgaatatcca tccaaatata tccaagtgaa tcattcgcac
    17761 catcagacac agcttccgaa gtcgtaactt gaggtgcact ctcattcatt tcaacatcat
    17821 acaaggccat gacatggtga accataaaat ttgttaactc ttctctgacg aaaacatcgt
    17881 agattcgagg attagagtag cttctaacag taaatcccgt ctcttccata acttctctag
    17941 tcagcgtttc cgtcagtcct tcaccaagtt gctgactgcc tccaggtaga tcataccgat
    18001 gttgataagg gcctctcgct ttttcaatgc agagtaactt cccattttct aagcaaacag
    18061 cgtagactcc aaagtgtttt ttgatttcca tccaactcct cctacttcaa agaccagcca
    18121 ccatctattg tcaagatttg tccttgcatg gcgctcgctt ttccacttgc taaaaaaaga
    18181 ctaagctctg ctatttcctc tggctcaatc cagcgcttga ttggggtttc actagccacc
    18241 cagtcagcca aaccacctgg ttcaaaatcc gcagcggtca tagctgtctt gactgctcct
    18301 ggagcgatcc caaagacctg aatcccagct tcagcatagt ctagagccaa ctgcttggtg
    18361 aagccagcca aggcatgctt ggatgaagta taggcgtgac cacctccacc tgctaggcta
    18421 gaagcaatgg aacacatatt gatgatgatt ccctttttat tttccagcat ttgtgtcaaa
    18481 taataccgag tcaactctac tggaataatg tagttgattt caaaaatctc ttgaatgtcc
    18541 tgcgccgttt gttccaacag tggtttgtaa tcatccaaaa ctccggcagt attacacaaa
    18601 acatccacct gagggcacca gtcaaaaata ggttccaagt ccaaggtcaa atctctctgt
    18661 aaaaagtgaa aatcaccctc taagagtggc ttttcacctt ggtcaactcc ataaacttga
    18721 tagcccttct ctaaaaagag gcgagcttga gccaatccga tccctgaact cactcctgta
    18781 atgagtacac gtttagtcat gcacttctac ccaatccgtt gccaaaacat cacaagctgt
    18841 cgggctccac atggaaaaac cttctccttc tccagacacg ttgattagga aataaggtgt
    18901 catttcaagt gcaagcccat tttgctcgat ggtatcaaag agttggacat agttttccgc
    18961 acctccccaa ccagttcgta catattttct cttagccttt aacccaggca gaatctcttc
    19021 aaatgtcatg tttttctcct ttaattctac attcttcatt taattataac aaaaaaaccg
    19081 ctttaatacg gctttttgac tgtgatttat ttacatcttc ttctacttac ggcaaattat
    19141 tccctgcagc aagataaatt tcataccatt cttttcttgt taagctaaag tttgccgctt
    19201 ggctaacttc tctcaagtgc ttaggatttg tggtacctac aactgcctgc atttttgctg
    19261 gataacgcaa tatccaagaa atggcaatag ttgaagaggt tactccatat ttaatagcta
    19321 aacgatcaag tacttgattt aaagcttgaa atttctcatt tccaacaaaa ttccctttaa
    19381 aatacccgaa ttgcaagaca gaccatgctt gaatgaccac atcgtgtaat tggcaatatt
    19441 caaaaatgct gccatctcgc atagctgctt gactatcttc catattaaca tgaaaagctg
    19501 attcaaatcc tggagtaaaa gccgcactca attgtagctg attaacagct aacggctgct
    19561 tgacatcttt tttaagcaac tccatcatca taggattttg attagaaact ccaaaatctc
    19621 gaactttacc ttgtttataa aggagattaa aggcttctgc tacttggtca gattccatca
    19681 aagcatctgg tcgatgaagg agcaagctat ctagatgatc aatcttcaat ctttgcaaaa
    19741 taccgtctac tgattttata atatagtcct tagaaaaatc aaaataggta aattcttcaa
    19801 tgcgaatgcc atatttggac tgaatccaca tcttttctct taaatctgga cgatttttta
    19861 ggacaagacc taacagttct tcacaacgac cacgaccata aatatcagcc aagtcgaagg
    19921 cattgattcc aacagaaagt gctgtttcta caagctcttc aacttctttt acagacttat
    19981 cttttattct catcattccg agaacaattt ctgataattc tttgtcatct tgaccaagag
    20041 ttatgtatct catcaaattt ttctccttta atttctaaca ttcttccctt cattataaca
    20101 aaaaaccgct ttgcaacggc tttttgacta tacttcactc cattttatct tcttaaaccc
    20161 acggaacaag acaaagattc caataaagag gacagctaaa ggaataactt ttgtaaggaa
    20221 aacatttgaa attcccatcc actcataata acggagcaga gaacccacca caagatgggc
    20281 aataatcata ctgacaaatg gacgaaagac cgcttctttc caattccaaa taccgataac
    20341 tagcgaaatc gtaaagacag acaaactatc ccagggagcc ggaatataaa aggctccttc
    20401 ttgtatgaag cttgccattc ctacatatcc taaaacaact agaagaacta tagtcccaac
    20461 aacaatgtaa gtgccaattt tcattttagg agaatcttgg actaaacttc ttcgtaaaat
    20521 tgtggccaca agtccaaatc caatcagaaa aataagaagt tgccctaaaa atgtgagcaa
    20581 attgactgtt aagagaggac ctttagaaaa atcacttagt agttgataat aacgtaatac
    20641 cgccaggaca agaattggcg tcaaaaggga ctctttgata gaactgcgag gtgctccctt
    20701 gagaatctct ttcattattt ttttaggatt cttacctaga taatcctctg cactcatgcc
    20761 atctcgttct gcttctgaga aatctagcat catcaaatag atctgctctc tgagatagtc
    20821 ttcatcatag agaaatccag caagattaaa actttcccac aactcctcaa aatacttttg
    20881 attctcctca gaaaactcat gtagcaaagc gcttgtttct tcgtaatact tcattttctt
    20941 catggtttaa cccccattct taatcccttc tactttttga ctcaaatcgt cccattgttg
    21001 ccaaaagact gagacacgct cttctccttc tttcattaat gaaaaatact tccgatctgg
    21061 accatctggc gacgggcgca tgtcgcctct tatccattga tttttttcta acttttgcaa
    21121 caaaggataa atagttcctg gaacgatagt atcaaatcca gcctctcgca aagtctgaac
    21181 caactcataa ccataccgct ctttttgacc aatcatatcc aagacacaac cttcaagaac
    21241 accttttaat agctgagttt ctttcatcac ttctcccttc taatctattt tgtaatacct
    21301 actagtaact tcacctatag tatatcactt ctacactagt ttgtaaagca taatagttaa
    21361 tactcttcga aaatctcttc aaaccacgtc agcgtcgccc taccgtatgt atggttactg
    21421 acttcgtcag tttcatctac aacctcaaag cagtgctttg agctgacttc gtcagtttca
    21481 tctacaacct caaaacagtg ttttgagcaa cccgcggcta gcttcctagt ttgctctttg
    21541 attttcattg agtataaata aaaaaacaga actagcctga actagtcctg tctactttta
    21601 cccaatcaca cttccatttg gtacagctgg atcaactgtg agaagggtta atttgccatc
    21661 atgttcagct gagagaatca taccctggct gacatatttt ttcatcattt tacgtggttt
    21721 gaggttagca atgatttgaa ctttcttgcc gaccaattct tgttcatttg gatagtattt
    21781 tgcaattcct gaaagaatct gacgatcttc tccatcacca gcatccaagc ggaattgaag
    21841 caacttatct gaaccttcta ctttagacac ttctttgact tctgccacac ggatttcaac
    21901 cttgtcaaag tcttcaaact tgatttcatc cttgtttagt ttgagctcaa cttcgtccgg
    21961 attccattct ttttcgactg ctggtttatt gccttccatt tgttccttga tataggcgat
    22021 ttcttcttcc atatttagac gtggaaagat aggtgttcct ttggcaacta cagtcacatc
    22081 tgctgggaag tcagccaaac tcaagttttc aagactagaa acttcttcca aaccaagttg
    22141 agtcaaaact gcacgactag tttccatcat aaatggttca atcaagtgag caactacacg
    22201 aatgctggct gccaagtggc tcatgacact tgccaattgg tcacgaagag cttcatcctt
    22261 ggccaagatc catggtgcgg tctcatcgat gtatttattg gtacgagaga tcagagtcca
    22321 gactgcttca agcgcacgtg gatagtcaac tgcttccatg tgtgtatgga agtctgcgat
    22381 tgattgttct gcaacctcag caagaacatg gtcaaattca gtcacacctt ctacataggc
    22441 agggatttgt ccatcaaagt acttattaat catggaaacc gtacggttaa ggaggttccc
    22501 aaggtcatta gccaattcat agttgatacg gccgacatag tcttcaggag taaaggttcc
    22561 gtctgaacca actggaaggt tacgcatgag gtagtaacga agtggatcta gtccataacg
    22621 ctctaccaac atttcagggt aaacgacatt cccttttgac ttagacattt ttccgtcttt
    22681 catgacaaac caaccatggg caatcaaacg atcaggtaat ttaacatcca acatcataag
    22741 aaggattggc cagtagatag agtggaagcg aaggatgtct tttcctacca tatggaagac
    22801 tgttccattc cagaacttgt caaagttacc atgttcgtct tgagcgtagc caagagctgt
    22861 cgcatagtta agaagggcat caatccaaac gtagacaacg tgttttggat ttgatgggac
    22921 aggcactccc catgtaaagg ttgtacgaga taccgccaaa tcttccaaac ctggctcgat
    22981 gaagttgcgt agcatttcat taagacgacc atctggcgtg ataaattcag gatgagcttt
    23041 gaaaaattcg accaaacggt cttggtattt gctaaggcga aggaagtatg attcttcaga
    23101 aacccattca acctcatgac ctgatggagc aataccacca gtcacatttc cagcttcatc
    23161 acggaaaact tctgccagct ggctttctgt aaagaattct tcgtctgata ctgaatacca
    23221 accagagtat tcacccaagt agatatcatc ttgagcaagt aagcgttcaa agacctgtgc
    23281 gacaactttt tcatggtagt catcagttgt acggataaat ttatcgtatg agatatctag
    23341 taattgccag agttctttaa ctccaaccgc cattctatca acatagactt gaggtgtaat
    23401 accagcttct tccgctttct gctggatttt ctgaccatgt tcatcaagac ctgtcagata
    23461 aaatacatcg tagcccatca ggcgtttgta acgtgctagg acatcacatg cgatagttgt
    23521 gtaggcagaa ccgatatgaa gtttcccaga tggatagtaa atcggcgttg taatataaaa
    23581 attcttttca gacataattt ttcctttcca ggcaaatgaa acctgttttt ctaacacttc
    23641 attatatcac atttttaatg aatttcgata gggaaatcca tacaaaaaca agatagacga
    23701 gtgtccatct tgttgatctt attcataacg aagggcttca attggatcaa gtttcgatgc
    23761 cttgttggct ggcaagactc caaaaatcat accaacacta gccgaaactg caagactaaa
    23821 tagggcaact gggattgata ctccaacttc tataccttct attaaacctt gcagtaacaa
    23881 acctgctaag gcagttaaac cacttgcaat tgtcaagcca attaagccac ctaacaaggt
    23941 caaaatcatg gattcaatca aaaactgaat taaaatattg gcacgtgttg cacccaaagc
    24001 cttacgaaga ccaatctcac gagtgcgctc tgtcaccgaa accagcatga tgttcatgac
    24061 accagttcct ccaacaaaga gagaaatccc tgcgatggaa ctaataatcg tcgtcataaa
    24121 actaaacgat tgttgaattt ctgcaaatac aacggactca tctgccacct ggtattctcc
    24181 ctgttgtaag cctgcaagct ctgtcatttt tcgtgccagt tctggaccca gagttggggt
    24241 taaactggta tcattcactc gaaagacaat attagctatt tcatctacat taaaattcgc
    24301 agcaagggag atattggtag taataggcaa gccaccaaac ccatatattt ttgatctttt
    24361 agcctccgga ctagtataaa ccccaatgac ccggtaacta aatccattga cttctacaac
    24421 cttgttaata gcctcttgag gagattcaaa taaactaatg gacaattcct catctagcaa
    24481 aatgacactt gcaaactctt tgaaatcttg ctctctcaga ctacgacctg caataatttc
    24541 attcttaaca gcgtccatgt aagttctgtt tccacctgtc aaattagcat tctcaacctt
    24601 tttatcttga taggtcaaga tggcattcgt tgaattggtt acatagtaac tatccactcc
    24661 cttcagttta gctgcctctt gaacccagga ttcttgcggt tttggcggtt caacaggaac
    24721 ttcctcttcc tttccagaaa ccgtaaaagc tgattgtttc tgagtaaaag acccatcttt
    24781 acttttttta ggagagaaaa agacgctaat atttttctga gatttagtca tatctttatt
    24841 gacttgacga gatagggaat cacccaaagc cataatcaca acaactgatg aaacaccgat
    24901 aataatccca atcatagtaa gcaaagaacg catcttgtga gccatgatag atgaaaaggc
    24961 aaatttcaga ttctgcatct tagttttcct cctttcctaa ctgagcactg tcagacgaaa
    25021 tgaccccatc ccgaatgaca atctgacgtt tggcatagac agcaatctca ggctcatgcg
    25081 ttaccatgat aatggttttt ccttctttat tcaaatcaac caataattgc ataatttggt
    25141 tacctgtttt ggtatccaag gctcctgtcg gttcatccgc taggataata gaaggattgt
    25201 ttaccaaggc acgcgcaatg gctacacgtt gcttttgacc accagataat tctgaaggta
    25261 aatggtgact acgttctgtc aattcaacct tgtctaaata ttcctcagcc aacttgcgac
    25321 gttttgaaga cgaaactcct gcgtaaatca agggcaattc tacattttgc agagcattga
    25381 gcttcgatag aagaaagaac tgctgaaaga caaaaccgat ttgttggtta cggaccttag
    25441 ctagttgttt ttcaccaagc ccagccactt cttgaccttc aagataatat tctccactgg
    25501 ttggtgtatc caacatgcca atcgtattca tcagagtgga cttaccagac ccagatggtc
    25561 ccatgatggc tacaaattca ccctcattca cttctagatt gatatttttg agaacctgca
    25621 gttcttggtc accattacgg taacttctga agatattttt tagactaatt agttgcttca
    25681 tcagccttca cctcttttcc ttcttccaag gaagatgttg gattactgat gaccttagca
    25741 ccgttcgtta aaccagaagt gatttcttga ttttctgcgt cagcatttcc caatgaaacc
    25801 tcaacttttt tagccttttg ttgttcatcc acaatccaga cataattttt actatcatcc
    25861 attactagac tgctaacagg aacaagaata gccttagttt tgcttttaac ctcaatgttg
    25921 acagaaaaac cttgtttcaa atcaccaacc tcgcctgtca catcaatagt ataagggtat
    25981 ttagaacctg tattattccc ggctgctgga ctagctgctt caccattgtt tttaggatag
    26041 tcagaaatat agcttaattt cccagtccat tttttatcag gatacacttt agaagtaaag
    26101 cttacttctt gacctacaga aaggttggct agattgtact cagacaattc tcccttgact
    26161 tgtaaatttt cattgctgac aatatgaacc ataacttgac tcgcccctgt tggagattta
    26221 gaaacattgc tattgacttc gactacagtt ccctctaggg tactgagaac agttgttgca
    26281 tccaattgac tttgagcctt gcttaattgc gctgcagcat ctgcacgcgc atcacgggca
    26341 tcacccaatt gagcatcaat agaagcaaca gaatttccag ccactggagt tgggctttgc
    26401 accgttgcat cttctcctcc tactggcgct ggtaactgtg gaacctgagc tgaagcggct
    26461 tcatttcgtg cttgattgag ttcattgata tgacgatctg ccttagctac tgctcgacta
    26521 gctgaatcat aggccgcctg cgcttctgaa ctactgtact tgactaaagc ctgcccttcg
    26581 ctgaccttat cgcccacaga aacaaggatt tcatctaaat cacccttact agcatcaaaa
    26641 taaacatatt gttcattttt tgctgttact gtccctgaca ataaaacaga ggatgccacg
    26701 cttccttcct tggcaacaac aagatgagta ggctcatctt ttacagcagt ctgagaaggt
    26761 tgtctaaaaa gtaaaatccc cccggcaccc aatacaacta cactcgcagc accgattgct
    26821 gcatacagtt gccacttttt agctttacca ttctttttct tcataatgaa actccttttc
    26881 ttttttacaa tactttgcta ttataccaaa tttccctcca gcaaacaatg cagttcagat
    26941 ggaaataatg gcagttcagg attaaacaat cgttcggaat tttgcttttc tattgtacta
    27001 gatatataat acactatctt gacttatttg gcaagctttt ttgcaatttt ttgtgcgtag
    27061 cagatttttg caatcaaatc aaaaaaagaa taaaatataa ctatcaaaaa agacgctcta
    27121 ctatttaaaa gattacaaag gagttttcaa tgagagaata tgatatcatt gctatcggtg
    27181 gaggtagcgg aggaatcgct accatgaacc gtgctggtga acatggagcc aaagcagccg
    27241 ttattgagga aaagaaatta ggtggaacct gtgtcaacgt cggttgtgtt cctaaaaaaa
    27301 tcatgtggta cggggcgcaa atcgctgaga ctttccatca atttggagaa gactacggct
    27361 ttaagactac tgatcttaac tttgactttg caaccctacg tcgcaatcgt gaagcctaca
    27421 ttgatcgcgc tcgttcttct tatgatggta gttttaaacg caacggtgta gacttgattg
    27481 aaggtcatgc tgaatttgta gattctcata ctgtaagcgt aaatggtgaa ctgattcgtg
    27541 ctaaacatat cgtgattgct acaggtgccc atccaagtat tcctaatatt cctggtgctg
    27601 agctaggtgg ctcttctgat gatgtatttg cctgggaaga acttccagag tcagttgcca
    27661 ttctaggcgc tggttatatc gccgttgaat tagctggcgt actccacact tttggtgtca
    27721 agacagatct ctttgttcgc cgcgatcgtc ctttacgtgg ttttgattcc tacatcgttg
    27781 aaggtttggt caaggaaatg gaaagaataa acttgccact tcatactcac aaagtccctg
    27841 ccaagttaga aaaaactgct aaaggcatta ccattcattt cgaggatggt accagtcaca
    27901 cagctagcca agttatctgg gctacaggtc gccgtccaaa cgttaagggc ttgcaacttg
    27961 aaaaagctgg agtgactctg aacgaacgtg gctttatcca agtagatgaa taccaaaata
    28021 ctgttgttga gggaatctat gctctaggtg atgtaacagg tgaaaaagaa ctgactccag
    28081 ttgcaatcaa ggctgggcgt accctatctg aacgtctctt taacggaaaa acaactgcaa
    28141 aaatggatta ctcaactatt ccaactgttg tcttttcaca ccctgctatc ggaactgttg
    28201 gtttgacaga agagcaagct attaaagaat acggtcaaga ccaaatcaag gtttacaaat
    28261 caagctttgc atctatgtac tctgcttgca ctcgcaaccg tcaagaatcc cgtttcaaac
    28321 tcataacagc tggttcagaa gaaaaagttg tcggacttca tggaattggc tacggcgttg
    28381 atgaaatgat tcagggattt gccgttgcta tcaaaatggg agcaaccaag gctgactttg
    28441 atgcaactgt ggcaattcac ccaactgcat ctgaagaatt tgtaaccatg cgttaatcga
    28501 aacaaaagaa gctgatataa atatgtctgc ttctttttta atgattttcg aatcaacaaa
    28561 aaaattatcc aacttgacta gtcacgaaaa tcggctgtta cagtttttgt taccttgttt
    28621 ttaaaaaatg gttgacatcg actcctatat gagtataata gttagtatac attagaaaag
    28681 aggttaacta ttttgaaaaa agctcacgtt tatgctatcc ctgctattgg ggctgctctc
    28741 attgctgttt tggcacaaat cagtcttcca attggacctg ttcccttcac tctgcaaaac
    28801 tttgcaatcg gcttgattgc tactgtcttt agaccgagag aggctgtact ttctgctgga
    28861 ctctatcttc ttctaggtgc tatcggtctt cctgtctttg caggaggtgg agctggtttt
    28921 caggctttag ttggccctac tgcaggctat ctttggtttt atctcgttta ctctggactt
    28981 acttcctctc taaccaacag caagagtggt gttgttaaga tttttcttgc aaacctcttg
    29041 ggtgatgccc ttgtctttgt cggcgggatt ctcagcttgc atttcctagc tggaatggca
    29101 tttgaaaaag ctcttgttgt gggggttctt ccctttatca ttccagacct tggcaaactt
    29161 ctggctatta gttttattag ccgtccccta cttcaacgcc ttaaaaatca ggcttacttt
    29221 actaactaaa aaaggatacc gagttatcat gactcaatat ccttttttta ttttgaaaac
    29281 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaaacac
    29341 tgttttgagg ttgtggatga aactgacgaa gtcagtaacc atacatacgg caaggcaaag
    29401 ctgatgcggt ttgaagagat tttcgaagag tattagttgc ctttaaaggc atccaccatc
    29461 gtttgaaatt cttcatttga gagagtaatc cctttgccca ttttagtatg gtctggactc
    29521 caagcacgaa tatcaaactt tgcaggggca ccattaaagc tcacacggtt aatttccttg
    29581 gtccaacctt tttcgttttc agaaagagtc aacaagtgct cttcgatttc aaatgtaaat
    29641 tctgccattt tcttctcctt ttttagtttc attagtttat tcgtaaaatc ttgtagattt
    29701 taggaaaatt ttatataata ttgatataaa agaagggagg ccaatatgag acataaattc
    29761 cagcaagttc taaataaaat acatgatttt ttaaatggat atgaccaacc tgaccagact
    29821 gaaaccaact cccttacagc cactattgaa gaggctatcc agaaacaaac cgctgttcac
    29881 cttatcttat ctgagacaag ctttacaggt gacatcatca aatatgatca gcaaggccag
    29941 caaattatcg tgaaaaattt ttccaaaaat gtgagccgga ttatccgtat aagcgatatt
    30001 caacgcctgc gatttgtccc ctcaactgtc caaacagccc aaaaaaatag atttaagaaa
    30061 gagtgagatg tagttgcttc atcccactct ttttcttagc gaatttgttc aaaatgtaaa
    30121 tgaactgcga tatgatctcc ataaccactt ctttccaagt cacgttgtaa acgataggaa
    30181 atatagtgtt ctgcaatggt aatgtaacct gcgcccaata aacgatgttc aaccatagat
    30241 tgaatcatac tgatagtcgc acgttccacc ttggcttctt gtaaatccaa aactaccttc
    30301 ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca aaacataaac agtttgggct
    30361 gccttcaaga tggcttggta aatcttatct ggattaaatt cagcaatttc gccattacgt
    30421 ttgattactt gcataggttt ctcctttatt ctttgttttc tttgatttct gccagcattt
    30481 tttcttcttc tactgtcagt tgataatgtt caagtaaatc cggtctgcgc tcgtaggttt
    30541 tctttaaact ctcgtacaat cgccactgac gaatcttttc atggtggcca ctcatcaata
    30601 catctggcac gaccatgcct cgataatcat agggacgtgt gtactgagga tattctaaaa
    30661 gacctgaaga aaaactatca tcttggtggc tagactcctt gccaatcact tctggaatca
    30721 ggcgaactgt agcatcaatc atggtcatag ctgccaattc tccaccagtg aggacatagt
    30781 cgcctaggga aatctcatct gttaccaagg tcttaatgcg ctcatcataa ccctcatagt
    30841 gcccacagat aaagattagc tcttcctctt gagccaaatc ttcagcataa gcctgatcaa
    30901 actgctttcc agcaggatcg aggagaataa cgcgcggatt tttcttttca atagcatcaa
    30961 aggaatcgaa aataggttgt actctgagca acatgccctg accgcctccg tagggctcat
    31021 catctacatg acgggccttt tcagcatttt ctcgaaaatt atgatactgg atatccaaga
    31081 gccctttttc tcgagccttt ccaacgattg agtgctccag tggagaaaac atctctggaa
    31141 agagggttaa aatatcaatc ttcatcgtct aacccttcta agatttccac atcgacccgt
    31201 ttatttggaa tatcaacatt gagaaccact ggtgggatat aaggtaaaag caaatcacgt
    31261 ttgccttttc gtttgaccac ccagacatca ttagcacctg gttgcaggat ttccttgatg
    31321 gttccaacca agctatcacc ctcatagact tccaaaccga taatctcgtg atagtaaaat
    31381 tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct tgagactgta tcccttgtac
    31441 ttttcgatag tattgatatg gtacatatct ttgaatttaa taatgtcaaa gttcttctgt
    31501 ttacggtggc tagcgatggt cactgtttgg acaaactgat ctttttcatc aaacaaagcc
    31561 agctcagctc cttttttaaa ccgttcttct gcaaaatccg tcacagacaa gactcgcatc
    31621 tcaccctgta atccctgcgt attaacgatt ttcccaacat taaagtagtt catcttgtct
    31681 cctgtaatct ccttttttcc atcttattct gacaattctc gaataatagc cgcaattttt
    31741 tccgattctg accattgtaa ataatggtga ttccctccta aaatgagttt agtattggaa
    31801 gtccaatatt ctgattctct gtactctttt tctctataag gctgacaaaa aacaaataca
    31861 ggaatatgag cttctataga tacatcctca aaatcttcct cagtaatctc tccagatatc
    31921 tgaaattctg gatcttgatt ttccaactct aagccttttt cttgcattaa ttcccagatt
    31981 tttttattcg tttcaggact aaatgttgct tgagttaaat tcttcaaata aagttcaggt
    32041 ccatactcgt caatcagcct catctgctct tccatttctg gataaggatt ttctgaaaaa
    32101 tcagcaaaca tgactttttt agttgtcggt tcaattgcta ctaaagtctg acacttaatt
    32161 ggtttctcga gtaatttgca agctaaaatt ccactccaac tatgtgcaca aagtatatat
    32221 tcagaaatcc ctaattcttc aagtacttca taaaccacat ctgcaagatt atctagattt
    32281 tttccagctt ggtcatgaat cggactccta cctgtgttcg gaaaatcaat tgtcaaataa
    32341 ccaattgtag gaggaggttt ttcaagtata agtgaaaaat tttcataact tggtagcaaa
    32401 cctgctccgt ttagacaaac tagcactttc ttttgctttt gataagtaac agagaggcta
    32461 ccaatttctg tagatacttc aaacctcttc ataaagaaat ccactcattc tatataatga
    32521 attattaaaa atccttatcc tttattttat cacgttccaa ggattttctc aagttggagg
    32581 aaggggacaa catctctact ttcccttcaa gaatccttcc aaatcatgtt tatgttggta
    32641 attaacggct gcggttttgt ctttctcaaa gacagtcttg gtaaggtcaa tatgcttgat
    32701 agcagcaata gcgacggtgt agtaaatgat atcagccagt tctctggcaa gttcctcgtt
    32761 cgaatcctat cccttctttt cgaccagagc gcctattcaa aacctcggct acttctccga
    32821 cttcctccac taacttcata aagagacctt catcagtccg agactgctgt taatgttcga
    32881 gtaagtagtc ttggaattgc ctaaacgttc aatcttttat agtatattga aactagaata
    32941 gtacaccttt acttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc
    33001 ctgttattat ttcattttac tatatcttct attccacaca aaaaagcgag acatccgtcc
    33061 cgcccttctt atttttcgtc aataacgatt cttacttttt tgtattcagt tgggacagag
    33121 tagacaatcg ttcttatcgc agaaatagtg cgacccttac gaccgattac acgacccaca
    33181 tcgctttgat caagattcaa atgatattcc aaaaattctg gtgtatcttc aatcttgata
    33241 gttaaggcat ctggttgtga aattaagggt ttcacaatcg caataatgag attttcaatc
    33301 gtatccatct gtcaacctac tttaaactta ttttgagaat ttagaatcgt ggaatttttt
    33361 caatacgcct tcttttgaaa ggatgttacg tactgtgtct gaaggttgag ctccattagc
    33421 caaccatgca agaacgcggt cttctttcaa agttacttgg ttttcagcaa caagtgggtt
    33481 gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt gaacgtgaat ctgctacgtt
    33541 gatacggtag aaaggttttt tcttagaacc catacgagtc aaacggattt taactgccat
    33601 ttttaaagtc tcatttcttt aattttttat ttcggtgaaa tagctgagct atttagcaca
    33661 tgagctattt agcacatgtt ctattatagc agatttctgg catgtgtcaa gaaaaaaact
    33721 tgacagacta taaatttctt aaagtattta gaaatttgtt agaataggaa ataaatgttt
    33781 gaaagatact atccgtgaat actattttag aaaaatttta taaagaacac caagtcaaac
    33841 ccttcatatc gcctgaacga gatttggata cttggctcct aagtcccaag cccgttccca
    33901 agcgaaatat gaacttatta gcagatgatt cactagcagg agatatcatt ttactatgga
    33961 gaatccagtt tggtactttt accactgaaa catgatttta aaaactccca ttcgaatatg
    34021 attcaaaatt cgcttagaat caatgttttc ccactttttc aaaaaataaa ttttcatcta
    34081 atttaaataa ctttcaatta agtgtgaatt ttgcttaaaa tcattaaaaa acaccccatg
    34141 gtgtgaacca tgaagtgttg taaatgctgt gttgtagcta gttcttagcg tttagagaac
    34201 tggctagctt tacgagcttt cttaagatct ggtttccaaa atactttgag tacacttatg
    34261 gtattgatgc ccctaaacat ctaaaaactc tggtagaaaa agggtatgct cttgtcgaaa
    34321 cttcttttga ctcacttgac catctaaata ctaccatgaa aaagaatatc ctgaagaaga
    34381 agggagttac tggactttct aaaatgaaat cttgcgacct ggatcaagcc cttcatgagc
    34441 atttttcaga agaagaatta gctggtcact ttcatgtcct tctatggact tttttacaat
    34501 ggcattgcta tcacacccaa tacctatcta agcgcctggt tcgtaaactt tattgcagct
    34561 cttcctctaa atttcctaat tgttgaacca attgcccgtt ttatactaag ttcttttcag
    34621 aaaccattta ctggggaaga agttgaagat tttcaagatg atgatgaaat cccaactatt
    34681 atctaagcca gttctgtaaa ctactaatat ttgaaatcca cttcctttta gggtacaatg
    34741 gttataaatg aatttttgag aggatcagaa tgaaaaaact agcaaccctt cttttactgt
    34801 ctactgtagc cctagctggg tgtagcagcg tccaacgcag tctgcgtggt gatgattatg
    34861 ttgattccag tcttgctgct gaagaaagtt ccaaagtagc tgcccaatct gccaaggagt
    34921 taaacgatgc tttaacaaac gaaaacgcca atttcccaca actatctaag gaagttgctg
    34981 aagatgaagc cgaagtgatt ctccacacaa gccaaggtga tattcgcatt aaactcttcc
    35041 ctaaactcgc tcctctagcg gttgaaaatt tcctcactca tgccaaagaa ggctactata
    35101 acggtattac cttccaccgt gtcatcgatg gctttatggt ccaaactgga gatccaaaag
    35161 gggacggtac aggtggtcag tccatctggc atgacaagga taagactaaa gacaaaggaa
    35221 ctggtttcaa gaacgagatt actccttatt tgtataacat ccgcggtgct cttgctatgg
    35281 ctaatactgg tcaaccaaac accaatggca gccagttctt catcaaccaa aactctacag
    35341 atacctcttc taaactccct acaagcaagt atccacagaa aattatcgaa gcctacaaaa
    35401 aaggtggaaa ccctagtcta gatggcaaac acccagtctt tggtcaagtg attggcggta
    35461 tggatgttgt ggataagatt gctaaagccg aaaaagatga aaaagacaag ccaactactg
    35521 ctatcacaat cgacagcatc gaagtggtga aagactacga ttttaaatct taaaaaccaa
    35581 aaaaatacag tatccacatt cggtactgta ttttttttac tctcattctt aagttaaatt
    35641 attaaaatcc catatttggt ctatccagcc ttcataaaag tctggctcgt ggcagaccat
    35701 aaggatagat cccctgtatt ctttgagagc gcgtttgagc tcatcctttg catccacatc
    35761 caaatggttg gtcggctcgt ccagcactaa aacgttgttt tcacgattca tcaagagaca
    35821 gaaacgaacc ttggcttgct ctccccctga taatacttga atctggcttt caatatgttt
    35881 ggttgtcaaa ccacaacggg caagggctgc acggacttct gcttgattaa gggcaggaaa
    35941 ggcattccag acagcttcaa gaggagtttg gcgattaccg ccttctactt cctgctcaaa
    36001 ataaccaagt tctaaataat ctccacgctc cacttcccca gcgattggcg agataatgcc
    36061 caagagaatc ttcaagagag ttgtttttcc aataccatta gcaccaataa tcgcaacctt
    36121 ttgattgcgt tcgaaggtaa gatttaaagg cttagtaaga ggacggtcgt aaccaatttg
    36181 caagttcttg gcttggaaga taaagcgccc tggtgtacga gctggtttga aatcaaagga
    36241 tggttttggt ttctcacttt ggagttcgat aatatccatc ttatccaatt tcttttgacg
    36301 agacatagcc atattacgag ttgcaacacg ggctttatta cgagccacaa agtccttgag
    36361 gtctgcaatc tctttctgct ggcgttcgta ggctgcctct agctgagatt tcttcatagc
    36421 ataaacttct tggaactggt agtagtcacc agagtaacgc gtcagctgtt gattttccac
    36481 atgatagaca atattaataa cgtcattgag gaatggaata tcgtgcgaaa tgagaacaaa
    36541 ggcattctca tagttttgga gatagcgctt gagccaatca atatgctcag catccaagta
    36601 gttggtcggc tcgtccaaca gcaagatatc aggcttttca aggagaagtt ttgccaaaag
    36661 caccttggtt ctttgcccac ctgacaaaga agttacatcc gtatccatgc caaagtccat
    36721 aacaccaaga gcacgcgcta cttcgtcaat cttagcatcc aaggtataga aatcacgact
    36781 ctccagacgg tcttgaagtt ctcctacttc ttccatgaga gcatcaacat ccgcgccgtc
    36841 ttcagccatt ttcatataga ggtcattgat acgagcttca gctttgaaaa gctcatcaaa
    36901 agccgtacgg agaacatcac gcaccgactg tctttcagca aggacagagt gctgatccaa
    36961 gtaaccagcc gtcacatatt tggaccactc aacctttcct tcatctggca gcattttacc
    37021 agtcacgata ctcataaagg ttgattttcc ttcaccattg gcaccgacca ggccgatatg
    37081 ttctcccttg aggagacgga aggacacatc ttcaaaaatt gcacggtcac caaaaccgtg
    37141 actcagattt ttaacttcta aaatactcat tttaattcct tatcttgttt ttatgtaatc
    37201 gtttataaag gagccaagcc agatagccac ccaaagtgtt ggtccacaaa tcatcaatct
    37261 caaagacgcg attgaaatca aagaaaaagt ctaagattaa ttgcgtacac tcgattccaa
    37321 gactcacaag aaaactaaaa agaaggacct tttttgtttt ccgcaaattt ggaaatagat
    37381 aaaggagttg gaaaatcaga ggaaaaaaca agaagacatt gaggatattt tgtaaaaaaa
    37441 tccaacataa ttgtccaatg tcactcactt cgcccagttt ccagagagaa ttgaaaggag
    37501 tcaaaagaaa aaccaggcgt ccaagatgct gaatacctgg agttcccact cccacggtag
    37561 attgttcttg aggagtaaag caaaaacaga caatgcaaat gctatagaaa atgactcccc
    37621 agaccaaaat atgattataa gtcttcttca tcattaagga tttaccgctg cgactgcctt
    37681 ctggcggtca cgtttcattg tgttaaagcg caattgtcca caagctgcgt caatatctgt
    37741 accatgctct tgacgaacca cacagttgcc cccttttttc ttaagcgtat catagaaagc
    37801 caacacgcgc tctttgggac tacggctata ttggtcatgc tcactaactg ggttataagg
    37861 aatcaagttt acataagaca atttcttgat gttcttgagc aattcagcca attccaaggc
    37921 ttgttctaca ccgtcattga cttcattaag catgatatat tcaaaggtta cacgacggtt
    37981 tgttgtctca atgtagtatt caatagcagc aaagagtttt tcaatcggaa aggcacggtt
    38041 aatcttcatg atacttgaac gaagttcatt gttgagtgcg tgaagagaca cggcaagatt
    38101 gatctgaacc ccttcatcag caaagtcacg aattttatga gccaaacctg aggttgaaac
    38161 cgtgatgtga cgagcaccga tagccattcc tttatcatca ttgatagtac gaaagaaatt
    38221 caagacattg ttgtaattat caaagggctc accgattccc atgacaacga tatggttgac
    38281 gcgttcatcc tgaccacgct catcaaagta tttctgaacc agcatgattt gcgctacgat
    38341 ttcaccgtta ttgaggtcac gctgcttctt aatcaaacca gaggcacaga aggtacaacc
    38401 gatattacag ccgacctgag tggtcacaca gacagataaa ccatagtgtt gacacatgag
    38461 tacagtctca attaacatac cgtcaggcaa ttcaaagaga tatttgactg taccatcagc
    38521 agactcttgc acaatacgtt gtttcaaggg attgaccaca aactggtcat tgagcttagc
    38581 aatcaaatcc ttggaaaggt tggtcatttc ttcaaatgac tgcacacgtt tacggtagag
    38641 ccattcccag atttgatctg cacggaattt cttttctccc tgctccaata cccattcctg
    38701 catggtttga tgtgccaaac tatgaattga gggtttcatt tcttctcctt attctctact
    38761 cacttctgac gaatgacaaa atgacgttgt tccttgtcct ctttctgaga atgctggtct
    38821 ttctgacgac gtctattttt cttatctgca ttcgactttc gtttagtttg agtcggtttc
    38881 tttccttttc tagaaggtgt ttcttcttcc gtcttacgca ttttcttgtc aaatgatgct
    38941 cgcttagggg cttcattttc taagacaaaa taggcacaac cataactaca atactctaaa
    39001 aggtagtctt gtaaacgact gattttttca agtttttctt ctgttcggtc atccttgtaa
    39061 aaacctcgta ggcgaagctg ttcgttgctc cagtccccca cgatataatc aaacttggtt
    39121 aatacttctg aaaaacgctg attaaaagtc gtcacatcaa aggcatcctt gatattttca
    39181 accaaggcaa aagctatccc ttccgtttcg accttgtccc cgtgtaaatg gaactccgga
    39241 ccaggaaact tgttatagtt gtataattca ggtgcaattt cttttcgcat agatatcctt
    39301 tttccacgat tacttaatac tttattctac cataatttct agcagttagc acgtttctca
    39361 taaaaatgaa aaaagtctga cgattttgtc agaccagaat cttataacct aaaaaagaga
    39421 agaacaattc ttccctccaa ctatcattat ttagcagctg cgtacaattc atctacttta
    39481 ttccagttga ttactgaaaa gaaagctttg atgtagtcag gacgcacgtt gcggtatttc
    39541 acgtagtaag catgttccca aacgtccaag cccaagattg gttttttacc ttctgagatt
    39601 ggtgtgtctt ggtttgctgt tgaagtcact tcaagtttcc cttctttgtt gacaaccaac
    39661 catgcccaac ctgaaccaaa acgagttgtt gctgctgcag tgaaggctgc ttggaattct
    39721 tcaaatgaac caaatgttgc atctattgct gctgccagtt ctgctgaagg agctgttttc
    39781 tcgggagtca tcaattccca gaaaagagcg tggttcaagt gtccgccacc attgttgata
    39841 agtgcttgac ggatatcagc tgggatagat tctacatcag caagcaaggc ttcaaggtct
    39901 tcaccgattt cagggtgttt ttctaaagct gcattggcat tgttgacata agtttgatgg
    39961 tgtttgtcat ggtgcaaatg cattgtttcc gcatcgatgt atggttccaa agcgtcgtat
    40021 gcatatggaa gttctggtaa gataatagcc atctgtaata cctctttttc tttctatatg
    40081 aaaatgataa cgcaaacatt cacttttttc aagttttttg cttatagata aggaaatcac
    40141 tgacatactt tctaataaaa taagcaaatc agcaagaaac ccacgacaag ataatcctga
    40201 cgcgagttgt agtttcaaca aatgtcaatt gacctgacta gcaatctgta agagtgcctt
    40261 ttcaaaaagg aaaccttttt cataaagacc tgtcttaatc tgatagtctg tctcaatcaa
    40321 ataggaaata gcttgcttca gaaagctcaa agaaagtcct ctcgaatctc ttaatgcaaa
    40381 cttgatttga taaggatttg ggttacgtcc cagataacta cctaaactac ttgcaatctg
    40441 cgattctgtt tggccagact ccgccaaaat cttcacctga gtaaaagtcc gaaattgtcc
    40501 cagcatgact gcaatcagtt tgatttcatc ttccccttgc aaggtcaagt ctctcaccaa
    40561 atcgcgcgcc tgatccatct ttttagtcag aataaactga gttaaatcaa aaatattgtc
    40621 ctgcaaggtc ttgggaattg cgttaacaat atcctcttcc tcaataacag aattcgcctt
    40681 ataggactgt aaaaagagaa gatttttctg gatttcgcta aattgaaacc ccgacttgat
    40741 gaggagattt tcaaaagaat gattggtaaa ctgcagacct tgtttctgac tccacttttg
    40801 gaaatactgg cgcaattctt gttcttttac ttctactgca tcgaagacct tggcatcacg
    40861 cttaagtaat ttgactaacc gtcttttgct atccagcttt ccttctgcaa agattatcaa
    40921 cttggttgtt ggagaaggat tgtcaaggta ttcctcaaat gacttaagct catcatctgt
    40981 caaaaagcgt ttcttagcag tcgtgatatc cataaaataa tctaatatca cgattttctc
    41041 atccgcaaag aaaggaaggc tgaccaactc cagttccaca tccttgtaaa ctacttcttt
    41101 catatcaaag taggcaaagt tgaggtcagc agaatcatac ccaatctgtt tcaacatttg
    41161 actcttcatc acttcaaact gaccctgatc tgtccctgta aataggctca ggctcggtaa
    41221 atttgataaa gtcaacttct gactttcttc aatggctagc atcgtctctc ctttcttcag
    41281 attttttgat ttaatttagt caatatagcg caatttccca cggaaatctt ctaagctctc
    41341 gtagcctttt tccaccatga ttgctttcag ttcattggta atgcagtcaa aagcactgac
    41401 gccttctttg tgaagggtcg ttcccacctg caccatactt gctccacaga ggatgtgttc
    41461 aaaggcatct cgaccagtca gaacgccacc tgttccgata atttggattt gaggatttaa
    41521 acgttgataa aaggcgtgaa cattggctag agcagtcggt ttgatgtatt ctccaccaat
    41581 tccaccaaaa ccattcttag gccgaataac gacagattcg tcttctatat agaggccgtt
    41641 tccgatagag ttaacgcagt tgacaaactt gagcggatat ttgttgaaaa tagctgccgc
    41701 ttgatcaaag tgaacaatat caaaataagg tggcaattta attccaagag gtttggtgaa
    41761 gtaagcaaac acttctgcca aaatccggtc tgttgtctca aaatcatagg caatctgagg
    41821 tttacctgga acatttggac aggaaagatt tagctcagtc agaccacgaa aatcactctc
    41881 ttggactttt ttcaaaatag tatgggtttc ctctggagac atgccgacca gagataagaa
    41941 gaaagttcgg ttcgactctt tttcctgcaa atctaaaaga taatccaaat aatagtctaa
    42001 gccattattt ggcaagccca tagagttgat ggaaccaagt ggaacatctt ggtagcgtgg
    42061 ctcaggattc ccctgacgga agtccaaggt cgctgtctta gtaacaaagg ttcctgccgc
    42121 tgagtttttg acctcttcta actcctctat cgtcatacaa gccacacctg ctgcattcat
    42181 caagcaattg tcaaactcaa aaccagcaat ttgtgttttc gttgatacca tgattctaat
    42241 cctccagatt tcttttattg ctaatattat accataattt taattctagg tttactagat
    42301 tctgtggttc tatctattta ttcggaaaag aaagtctagt acagaagtca tgctatggaa
    42361 acagctagtg tattggaagt ttgaacaagg cttgggtaac agacttttga atgaagtcca
    42421 agcaacaagg agaaatctca accatgagtc cattccatga ctctgttgct ctagaaaacc
    42481 ttgcaatagt caagtgataa cgaataaaac tttggcttga aatatcccca tgattatcta
    42541 ttacgaggag aaatctcaac ctttatcatt tttaaagaaa tattgtaaaa tgaaacaaga
    42601 acaggagaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagttgaggt
    42661 gtactattct agtttcaatc tactatacat gtaaatctct actttcgcaa aatggatttt
    42721 cagaacagta tcccagtata gttaaaaact ataaaaaaga gaggacgttc ccctcttaaa
    42781 atcttatttt actgcttctt tcaaagcatc taccttatcc aaacgttccc atggaagatc
    42841 aatatctgta cgtcccatgt gaccgtaagc cgatgtttga cggtaaattg gacgcttaag
    42901 gtccagcatt tggataatcc ctgcagggcg aaggtcaaag atttgacgag ccgctttttc
    42961 aagttgactt tcagctactg ttcctgtacc gaaagtatcg atacgaacag aaacaggttg
    43021 cgcaacaccg atagcatagg ccaactgcac ttctgccttc ttagcaaggt ctgctgcaac
    43081 gatattcttg gcaatatagc gagccgcata agaggctgaa cgatccacct tagtcgcatc
    43141 tttaccagag aaggcaccac caccatgacg agagtagcca ccataagtat ctacaataat
    43201 cttacgacca gtcaaacctg agtccccttg aggaccaccg attacaaaac gacctgtcgg
    43261 attgataaag aattttgtct tatcatcaag ataagaagat ggaataactt ctttgatgac
    43321 cttgtcaatc acatcttgat ggatttgttc attagtggcc tctggatcat gctgagtaga
    43381 aataacgact gtatctacac gtaccggacg gtcattttca tcgtactcaa ctgtaacttg
    43441 tgattttgca tctggacgga gatagctaat ttctccagac ttacgaagtt ctgccagacg
    43501 acgaaccaat ttatgactga gtgcaattgg caatggcatg agctcttctg tttcatctac
    43561 tgcaaatcca aacatgagcc cttggtcacc tgctccaatc aagtccagtg gatcttgatc
    43621 agcatttcca cgaacctcca aggcttcgtt aacaccttga gcgatgtcag gagattgttc
    43681 caccaaagat gggtgtactc ccaccgtctc agcagaaaat ccatattctg tattggtata
    43741 accaatctct gcaatggtat cacgaaccac acggttaata tccacatagg catttgtaga
    43801 aatttcacca aaaacgtgga cagaaccagt atatacagct gtttcagcag caacgtgcgc
    43861 ctctggatcc tttgctaaaa tagcatccaa aatcgcatct gaaatttggt ctgcaatctt
    43921 atccggatgc ccctcagata cagattcaga cgtgaataat ttacgctctg acataaaaat
    43981 gtcccccctt aaaaaatatt gttatagagt tacaaagtac tgataggaaa actcttcgta
    44041 ataaatacct accatcttat cgggactata taactttatc attataccat ttttaatcgc
    44101 aatttgcagt ctttaatgta gtgtttcggt ttagatagtt cgttctcata aagcaaaaag
    44161 ttggagctca atactccaac aatttctatt aaaatgtttg gcgtttagct ttacgctctg
    44221 cacgaccgcg agcgcgattt tcagcacgct tggttttacg gcgcttttca tcaaccgccc
    44281 attgaatttt cttcttataa cccggtttga cttttttctt tttcttttta accaaaccaa
    44341 tcatttcgat atcaagttta tcttgttttt tctcacggtt ggcacgacga tcacggtcat
    44401 aggtatcttg aaattccccg tctttgacca tcttaggact aaacttgatt cccaatttct
    44461 ccaactcacg gatatccgag tcatcacttg gctgataaag ggtaatagct gtacctggta
    44521 ggccatttcg tccagtacga ccaacacgat gaacaaaaaa agataagtct tgcggaatgg
    44581 catcattgat gacatggctg acaccttcaa tgtcaatccc acgcgctgct aaatctgttg
    44641 cgacaatata ctcaaaatcc agattttgca cctgattcat gattcgcttg cgttcacgag
    44701 gggcaatatc tccatggatt tttgcaacct tcaagccttg agcagtcaga tatgaatgca
    44761 attcatcagc acgcgtttta gtgttaacaa aaatcattgc caaatacggc tgcatcaact
    44821 gagtcaactg gtaaatttga gcattcttat catgtccctt ggtcgaaatc aaccaattat
    44881 caatggtgtc agaaataacc gttttggtct taattttctc cataacagga ttggataagt
    44941 attttttcaa gaatggttgc agtttttgtg ggatagtcgc tgagaagacc atgaattgca
    45001 agtcttttgg aagactgcca gcaatcttat caacagtttc caagaatccc atatccaagg
    45061 tcatatctgc ttcatcaaca acaaatgtct tggctttatg aatagctaaa tcaccagatt
    45121 taaccaagtc gtagatacgg cctggtgttc caataacaat atgaggctga ttgcttgcca
    45181 atttctcaat ctggcgagcc ttatccgtac cacccacata attaaccaca cgaacttcga
    45241 catctgagtg agctgaaatc tgacgcgcta cttggtaaat ttgagtagcc aactcacgac
    45301 tcggtgcagt aatcactgct tgtacactat cgctagcttc atctaattgc tggaaaatcg
    45361 gtaacaagaa agtatgagtc ttacctgaac ctgtttttga ttctcctact aggtcacgac
    45421 ctgccaaaac aataggaatc aacttgtctt gcacctctgt tggagttgta aattttaact
    45481 ccttcaaggc ttctctaata tagtttttaa attgaaattt cgtaaatgac ataacatcct
    45541 cgattctatc tatcttatca attataccat attttgaaca ttttcagtag tccgactcat
    45601 ctgacctatc acaaggctct caatttctct aaatatagta aaatgaaata agaataggat
    45661 gaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagcaga ggtgtactat
    45721 tctagtttca atctactata cctctcttat actaaaaatc atacatttgc tttctttcca
    45781 aaatgcaaaa agagaagacc aaattggtct tctctcagcc ttaaagcttg cgactcagat
    45841 agatttgtca aacagtcaaa cagttgctta agaatcttgt aaaagtcgaa agcttctaga
    45901 aaaattagta cttaatcatc tttccgcttg cgaccaagaa gcaacactgc tagacctgca
    45961 agaagagagc tagtcactag tccagtgagt gaaagtggtg cagtactacc cgcatttggc
    46021 aatgtagctt gtttttcctt ttctcctgct ggaccttgag ctggtggatt ctcttcaggt
    46081 tttcttggtt gttctgattg atgtctatct gcctgattat tatcagttcc ctgctctccc
    46141 cctggattca ctggtggaac tggatttggt tgaggtgctg gttgtggcgt tggtgccggc
    46201 tgtggttgtg gactaggatc ttgcttagct tcaaagaccc acttaccgac gaaggttaga
    46261 tttgacccct cttccacttc ttggtaacct aagaatgtcc atgtaccatt tgcaacagca
    46321 acttctacag gcatcggtgc ttctggaacg aaagcaatcg ctacagaaga acttgtagta
    46381 tatgttccac tttgtgggag taagctcaat acttctgctg gcaagttgtt gtctgcggtt
    46441 gcact
//
LOCUS       DAVMBH010000011        44736 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVMBH010000011 DAVMBH010000000
VERSION     DAVMBH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.011"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(99..1061)
                     /locus_tag="VYP30_000728"
     CDS             complement(99..1061)
                     /locus_tag="VYP30_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1807761.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            1127..2515
                     /locus_tag="VYP30_000729"
     CDS             1127..2515
                     /locus_tag="VYP30_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1807762.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRVGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(2550..3002)
                     /locus_tag="VYP30_000730"
     CDS             complement(2550..3002)
                     /locus_tag="VYP30_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1807763.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            3164..3457
                     /locus_tag="VYP30_000731"
     CDS             3164..3457
                     /locus_tag="VYP30_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807764.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            3613..4827
                     /locus_tag="VYP30_000732"
     CDS             3613..4827
                     /locus_tag="VYP30_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1807765.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            4972..5106
                     /gene="rpmH"
                     /locus_tag="VYP30_000733"
     CDS             4972..5106
                     /gene="rpmH"
                     /locus_tag="VYP30_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1807766.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            5390..6271
                     /locus_tag="VYP30_000734"
     CDS             5390..6271
                     /locus_tag="VYP30_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1807767.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLV
                     VATSGFALLGRKTRRRK"
     gene            6576..7349
                     /locus_tag="VYP30_000735"
     CDS             6576..7349
                     /locus_tag="VYP30_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1807768.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            7349..7909
                     /gene="rnmV"
                     /locus_tag="VYP30_000736"
     CDS             7349..7909
                     /gene="rnmV"
                     /locus_tag="VYP30_000736"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1807769.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            7981..8880
                     /locus_tag="VYP30_000737"
     CDS             7981..8880
                     /locus_tag="VYP30_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1807770.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            9200..9496
                     /locus_tag="VYP30_000738"
     CDS             9200..9496
                     /locus_tag="VYP30_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1807771.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            9573..11603
                     /locus_tag="VYP30_000739"
     CDS             9573..11603
                     /locus_tag="VYP30_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1807772.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSIYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTEIGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRDLMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            11605..12246
                     /locus_tag="VYP30_000740"
     CDS             11605..12246
                     /locus_tag="VYP30_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807773.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            12239..12397
                     /locus_tag="VYP30_000741"
     CDS             12239..12397
                     /locus_tag="VYP30_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807774.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQILVHGYL
                     LDFASIEG"
     gene            12783..13655
                     /gene="rsmA"
                     /locus_tag="VYP30_000742"
     CDS             12783..13655
                     /gene="rsmA"
                     /locus_tag="VYP30_000742"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1807775.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            13657..14535
                     /gene="rsgA"
                     /locus_tag="VYP30_000743"
     CDS             13657..14535
                     /gene="rsgA"
                     /locus_tag="VYP30_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1807776.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            14546..15202
                     /locus_tag="VYP30_000744"
     CDS             14546..15202
                     /locus_tag="VYP30_000744"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1807777.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            15165..15827
                     /locus_tag="VYP30_000745"
     CDS             15165..15827
                     /locus_tag="VYP30_000745"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1807778.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            15829..17085
                     /locus_tag="VYP30_000746"
     CDS             15829..17085
                     /locus_tag="VYP30_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1807779.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            17075..18016
                     /locus_tag="VYP30_000747"
     CDS             17075..18016
                     /locus_tag="VYP30_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1807780.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEIYSQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            18283..19110
                     /gene="purR"
                     /locus_tag="VYP30_000748"
     CDS             18283..19110
                     /gene="purR"
                     /locus_tag="VYP30_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1807781.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            19177..20427
                     /locus_tag="VYP30_000749"
     CDS             19177..20427
                     /locus_tag="VYP30_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1807782.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERAAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            20553..21347
                     /gene="pflA"
                     /locus_tag="VYP30_000750"
     CDS             20553..21347
                     /gene="pflA"
                     /locus_tag="VYP30_000750"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1807783.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(21422..22348)
                     /gene="yidC"
                     /locus_tag="VYP30_000751"
     CDS             complement(21422..22348)
                     /gene="yidC"
                     /locus_tag="VYP30_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1807784.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(22426..22704)
                     /locus_tag="VYP30_000752"
     CDS             complement(22426..22704)
                     /locus_tag="VYP30_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1807785.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22738..23478
                     /locus_tag="VYP30_000753"
     CDS             22738..23478
                     /locus_tag="VYP30_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1807786.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVATGILIFHLS"
     gene            23534..24217
                     /locus_tag="VYP30_000754"
     CDS             23534..24217
                     /locus_tag="VYP30_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1807787.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            24330..25322
                     /locus_tag="VYP30_000755"
     CDS             24330..25322
                     /locus_tag="VYP30_000755"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1807788.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            25387..25926
                     /gene="rsmD"
                     /locus_tag="VYP30_000756"
     CDS             25387..25926
                     /gene="rsmD"
                     /locus_tag="VYP30_000756"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1807789.1"
                     /translation="MKIVSGIYGRRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYTKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            25916..26404
                     /gene="coaD"
                     /locus_tag="VYP30_000757"
     CDS             25916..26404
                     /gene="coaD"
                     /locus_tag="VYP30_000757"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1807790.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPIENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            26388..27425
                     /locus_tag="VYP30_000758"
     CDS             26388..27425
                     /locus_tag="VYP30_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1807791.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            27483..27713
                     /locus_tag="VYP30_000759"
     CDS             27483..27713
                     /locus_tag="VYP30_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1807792.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            27737..29020
                     /gene="murA"
                     /locus_tag="VYP30_000760"
     CDS             27737..29020
                     /gene="murA"
                     /locus_tag="VYP30_000760"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1807793.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            29013..29201
                     /locus_tag="VYP30_000761"
     CDS             29013..29201
                     /locus_tag="VYP30_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1807794.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            29240..30064
                     /gene="endA"
                     /locus_tag="VYP30_000762"
     CDS             29240..30064
                     /gene="endA"
                     /locus_tag="VYP30_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1807795.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            30355..31686
                     /locus_tag="VYP30_000763"
     CDS             30355..31686
                     /locus_tag="VYP30_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1807796.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(31884..31954)
                     /locus_tag="VYP30_000764"
     tRNA            complement(31884..31954)
                     /locus_tag="VYP30_000764"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31920..31922),aa:Cys,seq:gca)
     gene            32370..35981
                     /gene="rpoB"
                     /locus_tag="VYP30_000765"
     CDS             32370..35981
                     /gene="rpoB"
                     /locus_tag="VYP30_000765"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1807797.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            36014..39691
                     /gene="rpoC"
                     /locus_tag="VYP30_000766"
     CDS             36014..39691
                     /gene="rpoC"
                     /locus_tag="VYP30_000766"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1807798.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            39802..40215
                     /gene="ndk"
                     /locus_tag="VYP30_000767"
     CDS             39802..40215
                     /gene="ndk"
                     /locus_tag="VYP30_000767"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1807799.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(40725..41003)
                     /locus_tag="VYP30_000768"
     CDS             complement(40725..41003)
                     /locus_tag="VYP30_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEV1807800.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(41144..41776)
                     /locus_tag="VYP30_000769"
     CDS             complement(41144..41776)
                     /locus_tag="VYP30_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807801.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLNLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            complement(41778..43793)
                     /locus_tag="VYP30_000770"
     CDS             complement(41778..43793)
                     /locus_tag="VYP30_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1807802.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLTTSTEWHDY
                     SPNGNVLIVTPHYLERQNIPVDTTIKQKMNHLNVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(43896..44192)
                     /locus_tag="VYP30_000771"
     CDS             complement(43896..44192)
                     /locus_tag="VYP30_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1807803.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
BASE COUNT        13147 a         8660 c        10192 g        12737 t
ORIGIN      
        1 aaaacatgtt tttgaggttg tagatgaaac tgacgaagtc agtaaccata catacggtaa
       61 ggcgacgtga cgtggtttgc agagattttc gaagagtatt agccttccat atagtttttc
      121 aaagcctgtc ctgttagtcc ggcattgagg gcgatgagga gtttcaagcg agctttttgg
      181 gcgttgagtt ctttaacaaa gaaaacgcct gctttttgca actgtacgcc cccaccctgg
      241 taggcataaa caggctcggc aataccgtta aagcatcgtg ataccagagc gactggaatt
      301 cctttttgca gaaggctttc taatttttga gccgtttctt tgggaatatt accagctccg
      361 aaggcttgga taatcaaacc gtccaagtgt tctaaatcca gcatatcaat cagctcatct
      421 gtcataccag cataagccga gatgataggg actaaacctt gtatgtgatc aaggtcaaag
      481 cgaacacgag gttcagctgt tttgaagtag aggatttcct gtttcatgat gagaccgagg
      541 ggaccatgtg ttggagtctg gaaggtgctg acattagtcg tatgtgtttt ggtgacatac
      601 ttggcagcgt ggatttcatc gttcataacg accaaaactc ctttgtcagc agccctgtca
      661 tcgctggcca ctcgtaaagc acttaggtaa ttataaacac catcactacc gagctcattg
      721 gagctacgca tggctcctgt tagaacgata ggcatatggg gaacttccat ggtatcaagg
      781 aaataggctg tttcctctaa agtatcggtt ccgtgtgtga tcaccactcc atcgtagtta
      841 tctgcttcct ctttaatttt ctggtagagg accagcatat gtttgggttt gatatgggga
      901 cttggaagat taaaaaagtc caaggcgtgg acttggattc cttcaagtgg gttggacaca
      961 tggttcatgg gattatctga actcgtcaca acagcgccag aagcatcggc ctgcatggaa
     1021 atagttccac ccgtatgtaa aacaaggatt ttcttaggca tgatttacta actctttctg
     1081 aaatgtggta taatcattgt atcacaaaag gggagattgg aataggatgg aagtcaaagc
     1141 tgtttttttt gatatcgatg gaaccttggt caacaatcgc aagagtgttt tgaaatccac
     1201 taaggacgcg attaagattg tcaaagaaca aggggtacta gttggcgtag cgacagggcg
     1261 aggacctttt tttgttaagg aattgatgga cgatttggat ctggattttg cggtaaccta
     1321 taatggccag tatatcttta gtaaagacag agtcttgttc acgagcccta tttccaagtt
     1381 acatttgcgc catctaatta gctatgctaa aaaagagggc acggagattg ctctagggac
     1441 caaggatgcc atgttgggtt ctaaaatcat gtcctttggt ctgggttctt tttcccaacg
     1501 aattagtcgc ttcgttccct ctgttttaac tcggacggtg agtcagtctt ttaatcgcat
     1561 ggtcagcaag gttgttcccc aaaaggaaga ggacctgctt cacctgatga atcaacctat
     1621 ctaccaagtt ttgatgctga tgacaccaga agaatctgag aaggcggcag ctgattttga
     1681 agacttgaaa ttgacacgta gcaatccttt tgcatcggat gtcatcaatc agggaaattc
     1741 taaattagaa ggcattcgcc gagttgggaa agaatatggc tttgacctca accaagtcat
     1801 ggcttttggt gactcagata atgatcttga aatgctggct ggcgtcggta tgtcggtcgc
     1861 tatgggaaat ggtagtagca gtgtcaagga agctgccaag cacattacca ctagcaatca
     1921 acaagatgga atccacaagg ccttggaaca ttttggtgtt ttgtcttcag aaaaagtctt
     1981 tgtcagccgt gactatcatt tcaataaggt caagaccttc caccacatga tggatgaacg
     2041 aacccaagaa gaacctcgag cttgggattt agagggtgca acccataggg ttggttttaa
     2101 aatagaagaa ttggtggagt ttgttcgagc agccagtcct tctgaagaag attttggtca
     2161 agctgtatcg caacttcatc aggcccttga taaggcagca gataaagtag ccaagaagac
     2221 acctgctcag caagatttga tagggcaagt ggatgccttg attgacacgc tttacttcac
     2281 ctacggcagt tttgtcttga tgggggtgga cccagaacgt atttttgata ttgtccatca
     2341 ggccaatatg gggaaaattt ttccagatgg caaggctcat tttgatccag tgacccataa
     2401 aatcttaaaa ccagataatt gggaagaaaa atatgctcca gaacctgcta ttaaaaagga
     2461 actgcagcgc cagctcaagg cttacgaacg ccataaagag agaaataaat cgtaaacaaa
     2521 aaggagctag gggctccttt tctttgtgat tataaggttt tttcttgttc tctcacaacc
     2581 agcaaatcga ccttagcatg gcggagtatg tattcagatg aagagccgac caagaggcgt
     2641 tcaaaggcgt tgagaccagt tgcgccaacg aggatgaggt ccacttcctc ggcatctgga
     2701 atagtacgtg ctagcagggt ctttggattt cccatttcaa tgacgatatg aacatctgct
     2761 accccagcat ctttagcacg tttttcgtac tctttcatca gactttcagc gtcgacttgg
     2821 agttcttcgt aaacttcagc atcaaaggtg gatacgcttt ggagagcgcg tgtgtcaatg
     2881 acatgtgcga tggtgagttt agcgtcgttt cgtagagcag aatgaactcc cttgacaaaa
     2941 gccaagtccg cttccttaga accatcgatt gcgaccatga tattttggta acgttgtgcc
     3001 ataatgaaac ctcctgaaat tttcttacta taattgtaaa ccttttcact atagaagtaa
     3061 agcaaaaaaa gtatttttca aaagaatatt agggcttaaa atctatataa atatatgata
     3121 aaataaaaga aaggatagca ggaaagaagt gaaggaaggg agaatgatga aaaactcttt
     3181 tcaaaaatca aatttccttt attatggaat tatcctagtt tcagtcttgg tagaagtgat
     3241 catgatctgg caattagaga gtctggtacc gcttctttat ccaagtttta ttggattttt
     3301 agtctttcat gtactctacc atctaatctt atttctagtt gcaaaacgaa gtgggcgttg
     3361 ggattacttg atgatatggg ggcttttcct catgtttaat cttctttatg actcctttct
     3421 aggcttgctt tttctaggtt tatcttttgg tatgtgatgt gtctttgcaa aatacctgct
     3481 atctctacgt tcttaacctc gcctttagca aggtttttct tctatacgaa actagtaaca
     3541 catttcagta aacttgtcgc attctctttc tagtggtata atgttactat cctgatgaat
     3601 tgaggaaaca agatgaaaga atataacaag tctagtaagt tagagcatgt tgcttatgat
     3661 atccgtggtc ctgtattgga agaagccatg cggatgcgag cgaatggaga aaagatttta
     3721 cgtctgaata caggaaatcc agcagaattt ggctttacag cgccagacga ggtcattcat
     3781 gacttgatta tgaatgcgcg tgatagtgaa ggctattctg actccaaagg gattttctca
     3841 gcccgtaagg ccatcatgca gtattgccag ctgaagaaat tcccaaacgt agatattgat
     3901 gatatttacc ttggaaatgg tgtcagtgag ttgattgtca tgtccatgca ggggcttttg
     3961 gacaatgggg atgaggtctt agtgccaatg ccagactatc ctctatggac ggcggctgtc
     4021 agcctagctg gaggaaatgc cgttcactat atctgtgatg aagctgtgga atggtaccca
     4081 gatattgacg atatcaagtc aaaaatcact tccaatacca aggcaattgt ccttatcaat
     4141 ccaaataacc caactggagc cctttatcct aaggaactct tgctggagat tattgagatt
     4201 gcccgtcaaa acgatttgat tatctttgcg gatgaaatct atgaccgcat ggtaatggac
     4261 ggacatgtgc atacgcctgt ggcgagcttg gcaccagatg tcttctgtgt cagcatgaat
     4321 ggtctgtcaa aatcccaccg catagcaggt ttccgtgtgg gttggatggt cttgtctggc
     4381 cctaagactc atgttaaggg ctatatcgaa gggctcaata tgctgtccaa tatgcgcctt
     4441 tgctctaacg ttttggccca acaagtcgta caaacttcct tggggggtca ccaatcagtc
     4501 gatgaattgc ttcttcctgg tggacgaatc tacgagcaaa gaaatttcat ctataatgcc
     4561 attcaagata ttccaggttt gtctgccgtt aaacccaagg cggggctcta tatcttccca
     4621 aaaatcgacc gcaatatgta ccgtatcgat gatgatgagc agtttgtcct tgatttcttg
     4681 aagcaggaaa aggttctctt ggttcatggt cgaggcttta actggcagga accagaccac
     4741 ttccgtatcg tttaccttcc tcgtgttgat gagttagccc aaatccaaga aaagatgact
     4801 cgtttcttga aacagtatcg tagatagggc ttgcattcga aaaagctgga aacatttgcc
     4861 tagagctatt gacaaaagtg aaagaatcag atagaatagt aaagtatgtt tagtaactga
     4921 tcactttata gccggctaaa cgaatacaaa atctatgagg aggtattcat cgtgaaacgt
     4981 acttatcaac caagtaaact tcgtcgtgcg cgcaaacacg gattccgtaa ccgtatgtca
     5041 actaaaaatg gtcgtcgcgt attggcagct cgtcgtcgta aaggacgcaa agttttggct
     5101 gcataatcca aacgaattct atcaaaaatc agtaggaact cgagtctact gatttttatt
     5161 tttgtaaaaa agttcagtag atgcaaatgg attcggaagc gatgttatag tagattgaaa
     5221 ctagaatagt acacctctat ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc
     5281 gatttgtcct gttattattt cattttacta taaagttgaa gtagctggag atggcacagc
     5341 gacaatcgtc tttaaagatg gttcagctat tacaattcca ggaaatcaat tggtagcaca
     5401 agatccaaaa gcacaagata gcactaaacc gactgctgaa aaatcaactg ttaaagcacc
     5461 tgctcaaaga gtagatgtaa aagatataac tcatttaaca gatgaagaaa aagttaaggt
     5521 tgctatttta caagcaaatg gttcagcatt agacggagcg acaatcaatg tagctggaga
     5581 tggtacagca acaatcacat tcccagatgg ttcagtagtg acgattctag gaaaagatac
     5641 agttcaacaa tctgcgaaag gtgaatctgt aactcaagaa gctacaccag agtataagct
     5701 agaaaataca ccaggtggag ataagggagg caatactgga agctcagatg ctaatgcgaa
     5761 tgcaggcggt ggtagccagg cgggtggatc agctcacaca ggttcacaaa actcagctca
     5821 atcacaagct tctaagcaat tagctactga aaaagaatca gctaaaaatg ccattgaaaa
     5881 agcagccaag gacaagcagg atgaaatcaa aggcgcaccg ctttctgata aagaaaaagc
     5941 agaactttta gcaagagtgg aagcagaaaa acaagcagct ctcaaagaga ttgaaaatgc
     6001 gaaaactatg gaagatgtga aggaagcaga aacgattgga gtgcaagcca ttgtcatggt
     6061 tacagttcct aagagaccag tggctcctaa gacaacaagt gcaccgcaag caactgcagg
     6121 aacaatgcaa gatgttacct accagtcacc tgctggcaaa caattaccta acacaggttc
     6181 agcatcaagt gcagcacttg ctagtcttgg tctagtggtg gcaacaagtg gttttgcttt
     6241 gctaggaaga aagactagac gtagaaaata gaacagctag aaaattctat tctctactta
     6301 aagttagatt ataaggggga ttttgagaag tcatcaatcc tagtgatggg tgagaaaagt
     6361 gagaacccaa gataatcaca tactttagct gaataggaat attctatcaa tgtagccaat
     6421 ctcttctgtc tctaactgtg gaataggaga tgggcaatat cggatagaaa agatagcaga
     6481 atagctctct attgaagaga ggaggggaaa ccgaaaaatt aggtgcccct cctctttttt
     6541 ggtataatag aagatagaaa acgaggttag aagagatgat ttttgataca catacacact
     6601 tgaatgtaga agaatttgca ggtcgtgagg cagaagaaat tgccttggct gctgagatgg
     6661 gtgtgacaca gatgaatatt gttggttttg ataaaccgac gattgagcgt gccttggagt
     6721 tggtagatga gtatgatcag ctctatgcga ctattggttg gcatcctaca gaagctggta
     6781 cttatacaga ggaagttgag gcttacttgt tggataagtt aaaacatccc aaggttgtgg
     6841 ctttaggtga aattggctta gattaccatt ggatgacagc gcccaaagag gtgcaggagc
     6901 aggtttttcg ccgtcagatt cagctatcta aggacttgga tttgcctttt gttgtccata
     6961 cccgtgatgc gctggaagat acctatgaga ttatcaagag tgagggcgtt ggtcctcgtg
     7021 gtggtatcat gcattcattt tcagggacgc ttgagtgggc agagaagttt gtggatcttg
     7081 gtatgaccat ttccttctca ggagtggtga cttttaagaa ggcaactgac ctccaagaag
     7141 cagctaaaga gttacctttg gacaagattt tggtggaaac agatgcgcct tacttagcac
     7201 ctgtacccaa gcgtggtcgt gaaaataaaa cagcctatac tcgctatgtg gtcgacttta
     7261 tcgctgactt gcgtggtatg acgacagaag agctggcggt agcaacgact gcaaatgcag
     7321 aacgaatttt tggattggac agcaagtaat gaaagagaaa atttctcaag ttatcgtggt
     7381 tgaagggcgt gatgatacgg tcaatctcaa acgttatttc gatgtggaga cctatgagac
     7441 tcgaggttct gccatcaatg ctcaggatat agagcggatt cagcgcctgc accaacgtca
     7501 tggagtcatt gtctttacag acccagattt taatggggag cggattcggc gcatgattat
     7561 gacggccatt ccaacagttc ggcatgcctt tctcaagcga gatgaagctg ttccaaagtc
     7621 caagaccaag gggcgttctc tgggaattga gcatgccagc tatgaagacc tgaaaacggc
     7681 tctagctcag gtgacagaac aatttgaaca tgagagtcag tttgacatta gtcgtagcga
     7741 tttgattcgc cttggttttc tagcaggggc agacagccgt aagcgtagag aatatctcgg
     7801 agagactctc cgaatcggct attccaacgg caagcaactc ctcaaacgcc tagagttgtt
     7861 tggggttact ttggcagaag tggaagaagc tatgaaatct tatgagtagg aaagatgtag
     7921 ccgttacaat tttttaagtt tcacagtatt tttcgaagca ggtagaagag gaggcgtctg
     7981 atgttaattg gtcaaaaaat taaagagatt cggatagaaa aaggaattag tcgtccagat
     8041 ttttgtggag atgagcaaga actgacagtt cgtcaactgt cgcgaattga aagtggagct
     8101 tcgcaaccga gtttgcccaa gttagactat attgctcgcc ggctaggagt tccagtttat
     8161 agccttatgc cggatttttc agctcttcct tctgcttatt tagaattgaa ataccagatt
     8221 ttacgtgaac caatctatgg taaagaagag gagtacgata agaaggaagc gtgtttggaa
     8281 gagatttata aaacatactt tgataatctt cctaaagaag aacaattagc atgtgaagta
     8341 ttgcaggcgt gtttggatac ttctagaact agaaggcctg aatatgcaga gttaatactt
     8401 gaggaacata tgcctcagat tatagaaaaa gaagcttatt caataaatga tatgttgttg
     8461 attcgtttgt ttttttatca aatgctcatt agaaaagatc ttgccaaatt tataaatcaa
     8521 atcgaaaagc taatgctctt tcttttggaa cagaagaagg taactcaaat agagaattac
     8581 tttataatta gagatactct tatttcagga atgtgttgtc ttgaaaaggt aggagtaact
     8641 gattgtttta atgattatct atcgtgttta caagaaatta tggataaaac tcaagattat
     8701 caaaagaaac ctcttgtatt tatgtttttg tggaagcaag cattaagagt agaaagagat
     8761 tttagtttag ctgaatcatt ttatcagtct tctaaaacat ttgcgaagct aattggagat
     8821 ggatttctag taaagaaatt gacagaggaa tggcaagagg atgtcaaaaa atatttataa
     8881 acatagtgaa tcagtgacaa aaatgtcctt gtcctcgtat caaaacagtt ctaaagttcg
     8941 tctttagaac tgttttttta gatataagct aaaaataata tgaaatagtt agattttaag
     9001 gacattgatg tccttgatag tgtgataaag atggagtata atgactataa aagttcattt
     9061 cagggtgcta ttttgacaat ttagagaaaa acaaataatt ttagaatatc atttggtaat
     9121 ataatagtat caacgttgat aatggaaaga ggagcaagta actcaacaat cttgtaatca
     9181 aaaatagagg agtatcaata tgaaacaaac agttaaaaag ttagctcttg tagcgagcat
     9241 tgcagcaaca ttaggtggag gtgtatcagt tgcctctgca gccgttcaat acccagaagg
     9301 tggtgtttgg acttatggtt caggtaacgg tggtgcttac tcaaactact atcacccttc
     9361 aaaataccat agttcaacag ttgttagcag aaaaactggt tcatctgaca agggatatgc
     9421 tggtgctgga gggacttctc gtgcatggat tcgtacttct tggggagaga aagttgcatt
     9481 ctactataat gtttagaatg gtatagccct attgtttagc tttacttggt caccttctca
     9541 ctaagtgacc aagtaacttt ttggaggaaa tgatgaaacg tttatttatt ttgatttcaa
     9601 tggtattggt atcgctttat atggtgataa cttccgttga ccatcgagaa gagattttat
     9661 ttggtaacta tccttctgtt gatgtgacag gaatgatgat aaatcaacca gtagctagtc
     9721 gcgaagaggt gacagaggct ttgagtcact tggcggtaga gcacaatagt ctcattgctc
     9781 gtcgaatcgt tgagccaaat gaagctggag aaacacgctt tacctatgcc acttatggtg
     9841 agggaaagct tccagaaggt ctgaccattt cctccaagga gagtgcagaa acgagtgatt
     9901 tattagggtc ttacttgatt gtatcaggaa gtttggatgg agtgagctta cagaccacct
     9961 tgaaagagct tggttatcaa ggctttgttt cgaatggaga agatccattt tcgatagtct
    10021 tactattgac ggccacccct atggtgctac tgagtttagc tatttttctg ctgaccttta
    10081 tgagtctgac cctgatttat cggatcaaat cccttcgtca ggcagggatt cgcttaatag
    10141 ctggtgagag cttgtttgga gttgctctca gaccagtgtt agaagatgtg agacagctta
    10201 tctgctcagt gctggtatcc agtcttttgg gattggggat tctctggtat caaggtgcct
    10261 tgtttatggc aacggtgcaa ctggtcatca ttgctcttct actttatgga ttgaccttgg
    10321 cagggatttc taccttacta agtgtcgtct atctacttgg tttacaggaa aatagtctgg
    10381 tggatctatt gaaagggaaa ctccctctca aacgtatgat gacattgatg atggtggggc
    10441 aactcttagc tgtattggtg gtcggatcga gtgcgacagc tctcctaccc cactaccgtg
    10501 aaatgcagga aatggagaga gctagcaata aatggagcca gtcctcagac cgttaccgtc
    10561 tatcctttgg ttggtctagt gcatttgccg atgaagaagg aacgcgtaag gataatcgtg
    10621 agtggcagac atttactgaa gaacggttag ccaatacaga ctctttttat attatgagca
    10681 atgttgacaa tttctcagat ggagcagaag tggacctaga tggcaatcgt ctcagtgact
    10741 acacaccgtc agggaatgtt atctatgtct caccgcgcta tctgatagaa gaaaagatta
    10801 ccgtttcttc agagtttatg gacaagatgc aaaacttgtc tgagggagag tttgggctga
    10861 tcttgcctga gagcttgcga gagcagtcta tctactacca aggattgttt acagattacc
    10921 tgcaaaactt ttcatctgaa agtgtagaag tgacgagtca gaaacactac ctcccacagg
    10981 taaggctagc ttttacagaa ataggacagg aacgtttcct ctataatgat gggtacaaga
    11041 caacacgcca gtacctaaaa gatccgatta ttgtagttct aacgccgcaa gcgactggaa
    11101 caagacctgt tgcagggatg ttgtggggaa ctacggctaa tagtgccttg aaactagatc
    11161 gatatggaga cagcatcaca gctctaaaag agcaaggtct gtatcacaag gtttcttact
    11221 tggtaaaaag ccagctattt tttgccaagg tactaaatga caaacgggtg gagttttact
    11281 ctctccttat tgggacgatt ttgaccctgt ctacggctat cttgttattt gattccatga
    11341 atcttctcta ttttgagcag ttcagacggg atcttatgat taaacgtctt gctggtatga
    11401 caatctatga gcttcatggc aagtatttac tggcgcaagg aggagttctc ttgcttggcc
    11461 tagtcctatc tagtattttg acaagagatg gtttgattag cgctctagtt gtagctttgt
    11521 ttacgcttaa cgccctcttg attttagtaa ggcaggacaa aaaagaagaa gctggtagca
    11581 tggcagtatt gaaaggaaaa taagatgatt gatattcaag gattggaaaa gaaatttaat
    11641 gaccgcgcga ttttctctgg tttgaatctc aagctggaga agggcaaggt ttatgcctta
    11701 atcggaaaga gtggaagcgg aaagacgacg ctgctgaata tcttgggaaa gctagaaaag
    11761 atagatggag gaagggttct ctatcagggg aaagatttaa aaaccattcc cactcgtgag
    11821 tattttcgag atcagatggg ctatctcttt caaaattttg gcctcttaga aaaccaatca
    11881 atcaaagaaa atttggattt gggttttgtt ggtcagaaaa tctcaaaagt agaacgtttg
    11941 gaaaggcaag tgggggcttt agaaaaagtt aatctagggt atttggattt agaacaaaaa
    12001 atctatactt tatctggggg agaggcccaa cgagttgccc ttgctaagac tattttgaaa
    12061 aatccaccct tgattttggc agatgaacca acagcagctc ttgatcctga aaattcagag
    12121 gaggttatga atctcttggt ggatttgaaa gatgaaaatc gaattatcat cattgcgacc
    12181 cataatcccc tagtctggaa taaggctgat gaaatcattg atatgaggaa acttgctcat
    12241 gtgtgaaaaa atccgtattc gcagggtatc tgattatcct agtgccagag gtggtttaga
    12301 agatatcctc atcatggaaa atatgaccaa tcatctcctt ttggttcaaa tcctagtgca
    12361 tggctatttg cttgattttg ctagtattga agggtaaagg caaaagcatt atcgtttgaa
    12421 aaatttacct caaacggttg aactgacagt ggatgatgtg gaggaggatg tggatttgac
    12481 cctacccgaa aatagaagtt atcaagaagc tgattttttt gatactcaat gaaaatcaaa
    12541 gagcaaacta ggaagctagc cgcaggctgt acttgagtac ggcaaggtga agctgacgtg
    12601 gtttgaagag attttcgaag agtatgaacg tatgtttcga gagaagcgct aagtccctct
    12661 ttaaagattt ccaagactat ctttcttcat gaggaaagat agttttttgg tatgattttc
    12721 attcccaaaa tacaagggga atgtgttaca atagtagtaa cagataatag aaaagagaat
    12781 agatgagaat tgcagattat agcgtgacca aggcagtgct ggagcgtcac ggttttacct
    12841 ttaaaaagtc cttcgggcaa aatttcctga cggataccaa tatccttcaa aaaattgtgg
    12901 atacggctga aattgatgac caggtcaatg tcatcgaaat cgggccaggt attggtgcct
    12961 tgacagaatt tttggctgag cgtgcagccc aagtcatggc ttttgagatt gaccaccgtt
    13021 tggtgccaat tttggcagat actctgcgtg attttgataa tgtgaccgta gttaacgaag
    13081 atattctcaa ggttgatttg gcgcaacata tccagaattt taaaaatcct gacctgccaa
    13141 tcaaggtagt ggctaatttg ccttactaca tcacgacgcc tattctcatg cacttgattg
    13201 agagtggcat tcctttttgt gagtttgtgg tcatgatgca gaaagaagta gcggaccgca
    13261 tttcagccca gcctaacacc aaggcttacg gtagcttgtc tatcgccgtg cagtattaca
    13321 tgacagccaa ggttgccttt atcgtgcctc gtacggtctt tgtgccagcg ccaaatgtgg
    13381 attcagccat cttgaaaatg gtgcgtcgtc cagagccagc cgtagcagta gaagatgaga
    13441 actttttctt taaggtttcc aaggctagtt ttacccatcg ccgcaagacc ttgtggaata
    13501 acttgacagg ttactttggt aagactgaag aggtcaagga caagctgacc aaggctttgg
    13561 accaggcagg cttgtcacca agtgtgcgtg gggaagctct cagcttggca gaatttgccg
    13621 gtctagcaga cgcacttaaa gggcaaggac tctaagatgc agggacaaat cattaaagcc
    13681 ttggcaggtt tctactatgt ggagagtgat ggccaggttt atcaaacacg cgcgcgtggg
    13741 aatttccgta aaaaaggcca taccccttat gttggggact gggtggattt ctctgccgag
    13801 gaaaattcag aaggctatat cctcaaaatt cacgaacgga aaaacagtct ggttcgtccg
    13861 cctattgtca atatcgatca agctgtagta atcatgtccg tcaaggaacc tgattttaac
    13921 agcaatttgc tggatcgttt cttggttctt ttggagcaca agggcatcca tcccattgtc
    13981 tatatttcca aaatggattt gttggaagat aggggagaac tggattttta ccagcagacc
    14041 tatggtgaca tcggctatga ctttgtgacc agtaaagagg aactcctgtc tttgttaaca
    14101 ggcaaggtta cggtctttat ggggcagaca ggtgttggga agtcaactct tctcaataaa
    14161 ctcgtaccag acctcaatct tgaaacggga gaaatttcag acagtctagg tcgcggtcgc
    14221 cataccactc gagctgttag tttttacaat ctcaacgggg gtaaaatcgc agatacacca
    14281 ggcttttcat ctctggacta tgaagtatca agggctgaag acctcaatca ggctttccca
    14341 gagattgcta ctgttagccg agattgtaag ttccgtactt gtacccatac ccatgagccg
    14401 tcttgtgccg tcaaaccagc tgttgaagag ggtgttattg caaccttccg ttttgacaat
    14461 tacctgcaat tccttagtga aattgaaaat cgtagagaaa cctataaaaa agtcagcaaa
    14521 aaaattccaa aataaggaga aacctatgtc tcaatacaag attgctccgt caattctggc
    14581 agcagattat gccaactttg aacgtgaaat caaacgtcta gaagcaactg gggcagaata
    14641 tgcccatatc gatatcatgg acagtcattt tgtaccgcaa atcagttttg gtgcaggtgt
    14701 ggtcgagagc cttcgtcctc atagtaagat ggttttcgat tgccacttga tggtgtcaaa
    14761 ccctgagcat catctggaag attttgcgcg tgcaggtgca gacatcatca gtatccatgt
    14821 agaagcaacg cctcatattc atggcgccct ccaaaaaatt cgttcactcg gagttaagcc
    14881 ttcagtcgtt atcaatcctg gcacaccagt tgaagccatc aagcacgtcc ttcatctagt
    14941 tgaccaagtt ttagtcatga cggttaatcc aggttttggt gggcaagcct ttctgccaga
    15001 aaccatggat aaggttcgtg agttggttgc tcttcgtgag gaaaaaggtt tgaactttga
    15061 aatcgaagtg gatggtggga ttgatgacca aactattgct caagccaaag aagctggtgc
    15121 gactgttttt gtagcaggtt cctatgtctt taagggagaa gtcaatgagc gagtacaaac
    15181 tctcagaaaa caactggact agggttgcag tttttgcagg cggaaaccgc ggtcattatc
    15241 ggacagattt tgatgctttt gttggggtgg atcgaggctc gctctgggtc ttggaagaag
    15301 acttacctct tgctctagca gtcggagatt ttgattctgt gacggaagaa gagcgacagg
    15361 tgattcaaaa acgtgcccag cattttgtcc aagcccggcc agaaaaagat gatactgatt
    15421 tggaattggc tctcttgacc atctttaagc aaaatcctca ggctcaggtt actattttcg
    15481 gtgccttggg tggccgtatt gaccatatgt tggccaatgt ctttctgcct agcaatccta
    15541 agttggcacc ctatatgcat caaatagaaa ttgaggatgg gcaaaacttg attacttatt
    15601 gtccagaagg aatcagtcag ctagaacctc gttcagacta cgactatcta gcctttatgc
    15661 cagttcggga tagccagctg actattcttg gagccaagta tgagttgaca gaggaaaatt
    15721 ttttctttaa aaaagtgtac gcttctaacg aatatataga tagggaagtg tcggtaactt
    15781 gcccagatgg ttatgtggtc gtactgcata gcaaggacag gaggtaggat ggaaagttta
    15841 cttattctat tattaattgc caacctagct ggtctttttc tgatttggca aaggcaggat
    15901 aggcaggaga aacacttaag taagagcttg gaggatcagg cagatcattt gtcagaccag
    15961 ttggattacc gctttgacca agccagacaa gccagccagt tagaccaaaa agatttggaa
    16021 gtggctgtca gcgaccgttt gcaagaagtg cggattgaat tgcaccaagg cctgacccaa
    16081 gtccgtcaag aaatgacaga taatctcctc caaactagag acaagacaga ccaacgtctc
    16141 caagccttgc aggaatcaaa tgagcaacgt ttggaacaaa tgcgccagac ggtcgaggaa
    16201 aaactagaaa agaccttgca gacacgctta caggcttcct ttgagacagt ttctaaacaa
    16261 ctggagtctg tcaatcgtgg tcttggagaa atgcagacag ttgcccgtga tgtcggagct
    16321 cttaacaagg ttctctctgg aaccaagacg cgagggattc tgggagaatt gcaactgggg
    16381 caaattattg aagacatcat gacacctgcc cagtacgaac gagaatacgc aacggttgaa
    16441 aactctagtg aacgagtgga gtatgccatc aagttacccg gacaaggcga ccaagaatac
    16501 gtctacctac caattgactc taagtttcca ctggcagatt attaccgctt agaagaagcc
    16561 tatgaagtag gtgacaagga tgaaatcgaa cgctgtcgta agtcactcct agcaagtgtc
    16621 aagcgttttg ctagggatat taggaacaag tacatagcac cacctcggac gaccaatttt
    16681 ggagttttgt ttgttccgac agaaggtctc tactcagaaa tcgtccgcaa tccggtcttc
    16741 tttgatgatt tgagacggga agaacagatt atcgttgcag gaccaagtac cctatcagcc
    16801 cttcttaact ccctatcagt tggtttcaag acccttaata tccaaaagag tgccgaccat
    16861 atcagcaaga ctcttgccag tgtcaagacc gagtttggca agtttggtgg tattctggtc
    16921 aaggcacaaa aacatctcca acatgcctct ggcaatattg atgaattatt aaaccgtcgt
    16981 accatagcta tcgagcggac gctccgtcac attgagttgt cagaaggcga gcctgcgctt
    17041 gatctactcc attttcaaga aaatgaggaa gaatatgaag attagtcaca tgaaaaaaga
    17101 tgagctattt gaaggctttt acctaatcaa atcagctgac ctgaggcaaa ctcgagctgg
    17161 gaaaaactac ctagccttta ccttccaaga tgatagtggc gagattgatg ggaagctctg
    17221 ggatgcccaa cctcataaca ttgaggcctt taccgcaggt aaggttgtcc acatgaaagg
    17281 acgccgagaa gtttataaca atacccctca agtcaatcaa attactctcc gcctgcctca
    17341 agctggtgaa cccaatgacc cagccgattt caaggtcaag tcaccagttg atgtcaagga
    17401 aattcgtgac tacatgtcgc aaatgatttt caaaattgaa aatcctgtct ggcaacggat
    17461 tgtccgaaat ctctacacca agtatgataa ggaattctac tcctatccag ctgccaagac
    17521 caaccaccat gcctttgaaa cgggcttggc ttatcatacg gcgaccatgg tacgtttggc
    17581 agacgctatt agcgagatct attctcagct caataagagt ctgctctatg cggggattat
    17641 gttgcacgac ttggctaagg tcatcgagtt gacgggacca gaccagaccg agtacacggt
    17701 cagaggcaat cttcttggac atatcgctct gattgatagc gaaattacca agacagttat
    17761 ggaactcggc atcgatgata ccaaggaaga agtcgttttg cttcgtcatg tcatcctcag
    17821 tcaccacggc ttgcttgaat atggaagtcc agtccgtcca cgtattatgg aggcagagat
    17881 tatccatatg attgacaatc tggatgcaag catgatgatg atgtcaacag ctctggcttt
    17941 ggtggataaa ggagagatgt ccaataaaat cttcgctatg gataatcgtt ccttctataa
    18001 accagattta gattgataat ttaagaaaaa tgagcatttt ttaggataag aatgttcgtt
    18061 tttttatgtg aatatggtat aataagtaaa agacaaaaat gaatactctt cgaaaatctc
    18121 ttcaaactag ggtagtatcg ctttgtcgta tgtatatatg caggtatatt acagggtttg
    18181 tcagttctat cgacaatctc aaaacagtgt tttgaaccac cagcgaccag ctttctagtt
    18241 tgctttttga ttttttgaat aaaaatggaa taggaaatag aaatgaaatt aagaagaagt
    18301 gatcggatgg ttgtcatttc caactatttg attaataatc cttataaact aactagtctc
    18361 aatacttttg ctgaaaagta tgagtctgct aaatcatcca tctcagaaga tatcgtcatt
    18421 atcaaacgcg cctttgagga aattgaaatc ggtcatatcc agacagtgac tggggctggc
    18481 ggaggtgtca tcttcacacc gtctatttcg agtcaggatg ctaaggaaat ggttgaagac
    18541 ttgcgtacca agttgtcaga aagtgaccgt atcttgccag gtggttatat ctatctgtct
    18601 gatttgctta gcacaccagc catcttgaaa aatattggtc gtattattgc caaaagcttt
    18661 atggaccaaa aaattgacgc ggttatgacc gtagcaacta agggtgtgcc acttgcaaat
    18721 gcagttgcca atgtcctcaa tgtctctttt gtcattgtgc gccgtgacct gaaaattacc
    18781 gaaggttcaa ctgttagcgt caactatgtt tcaggttcaa gtggtgaccg tatcgagaaa
    18841 atgttccttt caaaacgtag tcttaaggca ggcagccgtg tcttgattgt ggatgacttc
    18901 ttgaaaggtg gcggaacggt caacggtatg attagtctct tgcgcgagtt cgactcagaa
    18961 ctggcaggtg tagcggtctt tgcggacaat gcccaagaag aacgtgaaaa gcagtttgac
    19021 tacaagtcac tcttgaaggt aactaatatt gatgtcaaga accaagccat cgatgttgag
    19081 gttggcaata tctttgacga agataaataa gagatagaac taaaggttgg aacgattgtc
    19141 ccagcctttc tttgcaaaca gaatagaagg aagcttatga aaacaccatt tatcaataga
    19201 gaagagttag aagcgattgt tgccgagttc ccgactccct ttcacttgta tgatgagaag
    19261 gggattcgtg agaaggcaag agccgtcaac caagcttttt cgtggaacaa gggctttaag
    19321 gaatattttg cagttaaggc tactccaact ccagctattt tgaaaattct ccaagaagaa
    19381 ggttgtggtg tggactgctc tagttatgta gagcttttga tgagccataa actggacttt
    19441 ctgggttctg agattatgtt ctcttccaac aacacgccag acaaggaata cgcctatgca
    19501 cgtgaattgg gtgcgaccat taacttggat gcctttgaag atattgaaca tctggagaga
    19561 gcagcaggta ttccagaaat catctcttgt cgttataatc ctggaggcgt ttttgaactg
    19621 gggacagaca ttatggacaa tcctggggag gctaagtttg gcatgaccaa ggaccagctc
    19681 tttgaagcct ttgctatctt gaaggaaaaa ggagccaaga cttttgggat tcactccttc
    19741 ctagcgtcca ataccgtgac ccatctctat tatccagagt tggctcgtca gctctttgaa
    19801 ctggctgttg aaatcaagga aaagttgggc atttggctag actttatcaa tctttctggc
    19861 ggtattggtg ttaattatcg tccagaccag gagccgaacg atatcgcctt gattggtgag
    19921 ggagttcgta aggtgtatga agaagttctt acgtcagcag gtcttggtca ggtcaagatt
    19981 ttcaccgaat tgggtcgttt tatgctggca cctcacggtg ctctagtcac aagagtgact
    20041 cataagaagg aaacctaccg tacctatcta ggtgtggatg cctcagcagt caacctcatg
    20101 cgtccagcta tgtacggagc ttaccatcat attagcaacg tgacccatcc agatggacca
    20161 gctgaagcgg tagatgtggt tggttcactc tgtgaaaaca atgataaatt tgcagtcaat
    20221 cgcgaactgc ctcatacaga aatcggtgat ttgctggtca ttcatgatac aggtgcccac
    20281 ggattttcaa tgggctacca gtataatgcc aaattacgtt ctgcggaaat cctctatacc
    20341 gaagaaggta aagcccgtca aatccgccgt gcagagcgcc ctgaggacta ttttgcaacc
    20401 ttatatggct tcgattttga agaataatct gataatagat tgaaaatgaa attgaaaaac
    20461 agattgcttt ctaaaaaata ggcaaaaatc ttgtttttcc ttcaagtcgt gatataataa
    20521 aactataaaa cgttttcaag gaaggtaacg atatgtctga agaaacaatt gattatggac
    20581 aagtgacagg aatggtgcat tcgacagaaa gctttgggtc agtagatggg cctggtattc
    20641 gctttattgt ctttttgcag ggctgtcaca tgcgttgcca gtattgccac aacccagaca
    20701 cttgggctat ggagtccaat aagtcacgtg aacggacggt agatgatgtc ttgacagagg
    20761 ccttgcgcta ccgtggtttc tggggaaata agggtgggat tacagtcagt ggaggagaag
    20821 ctctcttgca gattgatttc ctgattgctc tcttcaccaa ggctaaggaa caaggaatcc
    20881 actgtacctt ggatacctgt gctcttcctt tccgtaataa accacgttac cttgagaagt
    20941 ttgacaaact catggctgtc actgacttgg ttcttttgga tatcaaggaa atcaacgaag
    21001 aacagcacaa gattgtcact agacaaacta ataaaaatat cttggcttgt gcccagtatc
    21061 tatcagatat tggaaaacct gtctggattc gccacgtgct agttccagga ttgacagaca
    21121 gagatgatga cttgattgaa cttggtaagt tcgtcaagac cctcaaaaat gttgataagt
    21181 ttgaaattct accttatcac accatgggtg agttcaagtg gcgtgaactt ggaattccat
    21241 attccctcga aggagtcaaa ccaccaacag cagatcgcgt caagaacgct aaaaaactca
    21301 tggataccga aagttatcaa gattatatga aacgtgtaca tggatagaaa agaagcctga
    21361 tggaaacatc gggcttttga tttgcaaaaa gacttagcaa atcagctaag cctttttctt
    21421 cttatctcga acgttgtttt ccagcgttgc gatttttgtg ttttttcttg cttgtgatag
    21481 cagttggttg ttcaggggta acgtcttttc gtccacttgg tttagagaaa gcacttgctt
    21541 ttggtgggtt cttggctagt tcttcacgga cttttttgcg aagttttgga cgaacgatat
    21601 agttgacgat aaactgttgg agaatcatca tgaaaccacc gacaacccag taaagtgtga
    21661 cactagctgg tgagaagagg gagaagacga cgatcatgag tgggctcatg taaatcattt
    21721 tcttgatttg ttctctttgc atttcatctt ctactccgtg aagtgaaagg agcgattgaa
    21781 gatagtaaag gacaccagca caggcaacca aaatcatact tggagaacct agaggaatgc
    21841 ctaggtagct tgcttgagca accccttcag tatgttgggc agcaaagtag atagcagaga
    21901 agaaaggcat ttgaaggagg atagggaaac atcctacacc accaaacatg ctgatgccgt
    21961 gctctttttg agcggcaaag agggcttgtt gggcttcgag tttttcttct tgagtagttg
    22021 cttctttgag acgtgtttgg tgtggctcaa ggacatgctt gagagcgttc atcttttcag
    22081 agtgaagcgt tgccttccat gattggtaga taccaagtgg taagataatc aagcgtacga
    22141 taatggttac gataatgata gcgacaccaa agcctagacc tttatcagta gcgaagtact
    22201 tgatggcttc agccataggc gctccgatcg tattccaaat aaatcctgtt ggctgacctg
    22261 tggttttatc gacattgaca cagccagtca agacaagcaa catagccact cccatagccg
    22321 agaatgcaaa acgtttaata gatttcactg tttttattcc ttctttaaaa attatacctt
    22381 tctattctac tgttttttta caaaatatac aatagttctg gagacctaat ttgcgatttt
    22441 aaagtcagag tagggaggaa agttgcttag tttgacatct aagtagctta cttttgaaaa
    22501 aggtgtcggt ccttttcgga tttcttggat aaattttgcc atgatagcag atgagtctgc
    22561 ttgggctaag atttccactg tgccatcgtc gttattccat actcgacctg tgatgccacc
    22621 aatttcaagt gccaagctgt aaacacccca acgaaagccg actccctgta ccctaccttg
    22681 ggcaatcatt ctaacctttt gcataccaac cccctttgat tgtgttataa tatttctatg
    22741 actattataa cctcaaaagc caattctgtg gtaaaaaatg ccaagaaatt acgccaaaaa
    22801 aaataccgca agtctgccta tttgattgaa ggctggcact tgtttgaaga agctgtccaa
    22861 gctggagtga cgattgagaa aatctttgcc ctagaaaatt atcgagatca gttagctact
    22921 ttttcgcaaa ctgtctgggt gtcagaggat attttgctag atttggcgga ttctcagact
    22981 ccacagggaa ttgtggcggt ggttcaaaaa gaagaagtag gacaagctga tttgagtcag
    23041 ggcaagttct tgtttttgga agatgtgcaa gatcccggta atgtaggaac tatcattcga
    23101 actgcggatg cagcaggttt tacaggagtg attgtttcag ataagtcggc agacatctac
    23161 agtctcaaaa ccctacgttc catgcaaggt agtcatttcc atctgcccat ttaccggatg
    23221 actagtcaag cgcttcttga cgaaactaaa aaggtagcta tcccagtgct agcaacaacc
    23281 ctatctaaag attctgttga ttacagagaa ctgccttcta tagaaaattt tgtactagtt
    23341 atgggaaatg agggtcaagg aattagtccc cttatggctg aaagtgcaga ccagttggtc
    23401 catattagca tgaaggggca ggccgagagt ttgaatgttg cagttgcaac cggtatttta
    23461 atcttccatt taagctaatt ttaacttttt ttgttataat caaggaaaga tgttcacaga
    23521 aaaggagaaa aggatgaatc acactattat acatgaccgt gcaggtctca atcaatttta
    23581 cgctaaggtt tatgcctttg ttggtctggg aatcggacta tctgctttgg tatcaggcct
    23641 tatgttgacg gtctttcagt ctcagttggt ttacttgttg atgcaggggc gtctctggtt
    23701 gaccattgct acttttgcgg agttggcttt ggttttcgtt gccagtagca tggcttcaag
    23761 aaatagtcca gctgctcttc cagtattttt actttactcc gttttaaacg gctttaccct
    23821 tagttttgtg gtggctttct atactccggg tacagtttta tctgcctttg tatcgagcgc
    23881 ccttctcttc tttgtcatgg cggcagttgg tatctttacc aagaaagact tgagtgggat
    23941 tggtcgagca atgatggcag ctctcattgg tttactgatt gctatggtag tcaatatttt
    24001 cttggctagt ggcttctttg attatatgat tagcgtagcc atggttttgg ttttttcagg
    24061 gttgattgct tgggataacc aaaagattcg cctcgcctat gaacaatcac aaggtcgtgt
    24121 agcgacaggc tgggtggtgt caatggctct cagcatctat cttgatttta tcaatctttt
    24181 cctaagtatt ctacgtatct ttggtcgcaa tgactaaaag gtctatgaaa tcagtgtttt
    24241 gagtgacact gatttttttt aaaattttct cttttctttt cttggaaata ggtgtataat
    24301 acgtttatta aatttttgag gagttgtcta tgaagaaaag ttttatccat caacaagaag
    24361 aaatttcctt tgtcaaaaac acttttaccc agtatttgaa agataagcta gaagttgtcg
    24421 aagttcaagg tcctatcttg agtaaggtcg gtgacggaat gcaggacaac ctgtctggtg
    24481 tggaaaatcc agtatcggtc aaggttctcc aaatccctga tgctacttat gaagtggtgc
    24541 actcacttgc taaatggaaa cgccacacct tggctcgttt tggctttggt gaaggagagg
    24601 gtctctttgt ccacatgaaa gcccttcgtc cagatgagga ttccttggat gcaacccact
    24661 ctgtttatgt tgaccagtgg gactgggaga aggttatccc aaatggtaag cgtaacatcg
    24721 tttatctaaa agaaacagtt gagaagattt ataaggctat tcgcctgact gagctagctg
    24781 ttgaagctcg ctatgacatc gagtctatct tgccaaagca aatcaccttt atccatacag
    24841 aagaattggt agaacgctac ccagacttga caccgaaaga acgtgaaaat gcgatttgta
    24901 aagaatttgg agccgtcttt ttgattggta tcggtggcga gttgccagat ggtaaaccgc
    24961 acgatggacg tgcaccagac tatgatgact ggacaagcga gtctgagaat ggctacaagg
    25021 gtctaaatgg tgatattctt gtctggaatg agtctttagg tggagccttt gagttgtctt
    25081 ctatgggaat tcgtgtagat gaagaaactc ttagacgtca ggtggaaatt acaggtgatg
    25141 aagaccgctt ggaattggaa tggcacaagt ctttgttgaa tggcctattc ccattgacaa
    25201 tcggtggagg aattggacaa tctcgtatgg ccatgttcct acttcgcaag agacacatcg
    25261 gagaagtgca aacaagtgtt tggcctcaag aagtccgcga tacttacgaa aatattttgt
    25321 agagaatcga accgcaaggt tcggttttct ttctcttttt gtctataatt tggtataata
    25381 aacagtatga aaatcgtatc aggaatctat gggagacgtc ccctcaagac actagaaggc
    25441 aagacaacaa gacctacttc ggataaggtt aggggagcca tttttaacat gattggtccc
    25501 tactttgaag ggggacgagt cttggacctt tatgcaggta gtggtggttt atctatcgaa
    25561 gcagtatcgc gtggcatgtc cagtgctgtt ttggtggagc gagaccgtaa ggctcagacc
    25621 atcgtggctg aaaatatcca gatgaccaag gaagttggaa aatttcaact cctcaagatg
    25681 gatgcagaaa gggcattgga acaggtatct ggggaatttg acctcgtttt cttagaccct
    25741 ccctatacca aggaacaaat cgtagcagat attgaaaaaa tggctgagag agagcttttt
    25801 tctgaagatg ttatggttgt gtgcgagacg gataaggccg ttgaacttcc agaagaaatt
    25861 gcctgtctgg gtatctggaa ggaaaagatt tatggaatta gtaaggtgac agtctatgtc
    25921 agataagatt ggcttattca caggctcatt tgatccgatg acaaatgggc atctggatat
    25981 cattgaacgg gcgagcagac tctttgataa gctctatgtc ggtatttttt ttaatcccca
    26041 caaacaagga tttcttccta tcgaaaatcg taaacggggg ctagaaaagg ctttgggaca
    26101 tctggaaaat gttgaagtcg tggcttctca tgatgaattg gtggtcgatg ttgcaaaaag
    26161 attgggtgct acttgtctag tgcgtggttt gaggaatgcg tcggatttgc aatatgaagc
    26221 cagttttgat tactacaatc atcagctgtc ttctgatata gagactattt atttacatag
    26281 tcgacctgaa catctctata tcagttcatc aggcgttaga gagcttttga agtttggtca
    26341 ggatattgcc tgctatgttc ccgagagtat tttggaggaa ataagaaatg aaaaaaaaga
    26401 ttagatggcc cttatacgtc attgcggcct tgattgtgac tttcttggca tttgtagtgc
    26461 ccttgcctta ttatatagag gttccaggtg gttcggaaga tattcgccaa gtccttaaag
    26521 taaatgacac agaagataag gaagctggtg cctatcaatt cgttacggtt ggtgttcaac
    26581 atgccacttt agctcatatg atttatgctt ggttgacacc ttttacagat attcgtagtg
    26641 ctcaggagac tacaggtggt tcttccgatg ttgaatttat gcgaatcaat caattctaca
    26701 tgcaaacatc acaaaatatg gccaagtatc aaggtctaaa aacagctggt aaggatatcg
    26761 aactcaagta ctttggggtt tatgtcttga atgtgacgga taattcaacc tttaaaggga
    26821 ttctcaatat ctctgatacg gtcacagcag tcaatgatca gacctttgat agttccaaag
    26881 acttgattga ttacgtcagt tctcaaaaat taggggactc cgtcaaggtc acctatgaag
    26941 aggatgggca aaccaagtct gcagaaggaa agattatcac cttggaaaat ggaaaaaatg
    27001 gaattggaat cggcttgatt gatcgtacag aggtaatcag caatgtccca attagctttt
    27061 caacagctgg tattggcggc ccaagtgctg gtctcatgtt tagtctagct atctatactc
    27121 aaatagctca cccagatctt cgtaatggtc gtattgttgc cggtacaggt accattgacc
    27181 gcgatggtaa tgtgggagac attggaggta ttgataagaa ggttgtagct tcggctaggg
    27241 caggtgctgc tattttcttt gctcctgata accctgttag cgaagaagaa caaaaggcgc
    27301 atccggacgc gaaaaacaac taccaaacag ccctagaagc ggctaaaaca atcaagacgg
    27361 atatgaaaat cgtgcccgtt aaaaccctac aagatgcgat tgattacttg aaaaacaatc
    27421 cctaattttt gagtgaagtt tccaaactag cgcacaaaca gagaagatgg tataatagtc
    27481 aaatggttca attattattc actctaagta gtcatatgct ctttatttat gtgagttttt
    27541 accttttaaa ggatcttgtt agatgggaga aggttttaaa agtgacagat gagaatacaa
    27601 gaaaagttcg tttattagta gcctttttta gcattgtcat aggctacatc ctgagttctt
    27661 tctttattag cctgtatcat ttgtggcaag aagcgcttag aggattatta tgaaatcaag
    27721 agtaaaggaa acgagtatgg ataaaattgt ggttcaaggt ggcgataatc gtctggtagg
    27781 aagcgtgacg atcgagggag caaaaaatgc agtcttaccc ttgttggcag cgactattct
    27841 agcaagtgaa ggaaagaccg tcttgcagaa tgttccgatt ttgtcggatg tctttattat
    27901 gaatcaggta gttggtggtt tgaatgccaa ggttgacttt gatgaggaag ctcatcttgt
    27961 caaggtggat gctactggcg acatcactga ggaagcccct tacaagtatg tcagcaagat
    28021 gcgcgcctcc atcgttgtat tagggccaat ccttgcccgt gtgggtcatg ccaaggtatc
    28081 catgccaggt ggttgtacga ttggtagccg tcctattgat cttcatttga aaggtctgga
    28141 agctatgggg gttaagatta gtcagacagc tggttacatc gaagccaagg cagaacgctt
    28201 gcatggtgct catatctata tggactttcc aagtgttggt gcaacgcaga acttgatgat
    28261 ggcagcgact ctggctgatg gggtgacagt gattgagaat gctgcgcgtg agcctgagat
    28321 tgttgactta gccattctcc ttaatgaaat gggagccaag gtcaaaggtg ctggtacaga
    28381 gactataacc attactggtg ttgagaaact tcatggtacg actcacaatg tagtccaaga
    28441 ccgtatcgaa gcaggaacct ttatggtagc tgctgccatg actggtggtg atgtcttgat
    28501 tcgagacgct gtctgggagc acaaccgtcc cttgattgcc aagttacttg aaatgggtgt
    28561 tgaagtaatt gaagaagacg aaggaattcg tgttcgttct caactagaaa atctaaaagc
    28621 tgttcatgtg aaaaccttgc cccacccagg atttccaaca gatatgcagg ctcaatttac
    28681 agccttgatg acagttgcaa aaggcgaatc aaccatggtg gagacagttt tcgaaaatcg
    28741 tttccaacac ctagaagaga tgcgccgcat gggcttgcat tctgagatta tccgtgatac
    28801 agctcgtatt gttggtggac agcctttgca gggagcagaa gttctttcaa ctgaccttcg
    28861 tgccagtgca gccttgattt tgacaggttt ggtagcacag ggagaaactg tggtcggtaa
    28921 attggttcac ttggatagag gttactacgg tttccatgag aagttggcgc agctaggtgc
    28981 taagattcag cggattgagg caagcgatga agatgaataa gaaatcaagc tacgtaatca
    29041 atcgtttact tttagtcatc atagtactga ttttaggtac tctggctcta ggaatcggtc
    29101 taatggtagg ttatggaatc ttgggcaagg gtcaagatcc atgggctatc ctgtctccag
    29161 caaaatggca ggaattgatt cataaattta caggaaatta ggctggagaa ccagcctttt
    29221 tctaaagata aggagaaata tgaacaaaaa aacaagacag acactaatcg gactgctagt
    29281 gttattgctt ttgtctacag ggagctatta tatcaagcag atgcagtcgg cacctaatag
    29341 tcccaaaacc aatcttagtc agaaaaaaca agcgtctgaa gctcctagtc aagcattggc
    29401 agagagtgtc ttaacagacg cagtcaagag tcaaataaag gggagtctgg agtggaatgg
    29461 ctcaggtgct tttattgtca atggtaataa aacaaatcta gatgccaagg tttcaagtaa
    29521 gccctacgct gacaataaaa caaagacagt gggcaaggaa actgttccaa ccgtagctaa
    29581 tgccctcttg tctaaggcca ctcgtcagta caagaatcgt aaagaaactg ggaatggttc
    29641 aacttcttgg actcctccag gttggcatca ggtcaagaat ctaaagggct cttataccca
    29701 tgcagtcgat agaggtcatt tgttaggcta tgccttaatc ggtggtttgg atggttttga
    29761 tgcctcaaca agcaatccta aaaacattgc tgttcagaca gcctgggcaa atcaggcaca
    29821 agccgagtat tcgactggtc aaaactacta tgaaagcaag gtgcgtaaag ccttggacca
    29881 aaacaagcgt gtccgttacc gtgtaaccct ttactacgct tcaaacgagg atttagttcc
    29941 ctcagcttca cagattgaag ccaagtcttc ggatggagaa ttggaattca atgttctagt
    30001 tcccaatgtt caaaagggac ttcaactgga ttaccgaact ggagaagtaa ctgtaactca
    30061 gtaaaagata agcctaaact cctatgtcac ttatggatgt aggagttctt tttactagtt
    30121 taagcagggc tagaataggt actaataaaa aatagtaact tctaaaacta acttccagtt
    30181 tcccacaacc tagcttttag tatgagaaaa acgcgtgaaa tcagtggaaa tccgtcttag
    30241 actaacttcc agttttggga gagagatgga agttacgcta agaaaaaaat aatatgtatt
    30301 ggattaaatt ttgtgatata ataaaggata agatactatt ttaggagaag aactatggaa
    30361 gacccaagta gtcagaattt gttgctacaa tttgttttat tgtttatctt gacggtatta
    30421 aatgcctttt tctcagccac agaaatggcc atggtttctc ttaatcgtgc ccgagttgaa
    30481 caaaaggcgg aagaaggaga cagacgctac atccgcctgc tgaaggtact agaaaatcct
    30541 aaccactttt tatcaaccat tcaggtagga atcaccctga ttacaatctt atcaggggcg
    30601 agtttaactg atactctagg acgtgtgatt gcctcttggc ttgggaatgg cgaaacagca
    30661 caagccgtgg caacttttct atccttggca tttttgacct atatttccat cgtttttggg
    30721 gaattatatc ctaagagaat cgctcttaat ctaaaggatg ccttggcaat tcgtacagcg
    30781 ccgattatca ttgggatcgg aaaactagtc agtccttttg tttggctttt agctgcttcg
    30841 accaatttct tgagccattt gactcctatg tcattcgatg atgcggatga aaagatgacc
    30901 cgtgatgaaa ttgcctatat gctgacaaat agtgaagaaa cattggatgc tgatgagatt
    30961 gagatgctac aaggtgtctt ttcgctcgat gaactgatgg cacgagaggt tatggtgcct
    31021 cgaacggatg cctttatggt ggatattcag gatgatagtc aagccattat ccaaagtatt
    31081 ttaaaacaaa attattctcg tatcccggtt tatgatgggg ataaggacaa tgtaattgga
    31141 atcattcaca ccaagagtct ccttaaggca ggctttgtgg acggttttga caatattgtt
    31201 tggaagagaa ttttacaaga tccacttttt gtacctgaaa ctatttttgt ggatgacttg
    31261 ctaaaagaac tgcgaaatac ccaaagacaa atggcaatct tgctggatga atacggtggt
    31321 atggctggtt tggtgacttt ggaagacctc ttagaggaaa ttgttggtga aattgatgat
    31381 gaaacggaca aagcagcaat agatgttcat cagattggcg aggataccta cattgttcaa
    31441 ggaactatga ccctcaatga tttcaataat tactttgatg ttgaactgga aagtgatgac
    31501 gttgatacca tcgctggtta ttatttgaca ggagtgggaa ctattccaac gactgagaaa
    31561 ctcagctatg aattggtcag ccaaaacaaa cagtttatct taaccaatga taaagtgaag
    31621 aatggacgtg ttaccaaggt aaaagtccaa atcacagaag tcgaaataga agaagaaaca
    31681 gaataaacta gaggcttttg tcaccaggcg tgacgaagct tttttcaatt gatttcaaaa
    31741 gggaattatg ccatggaaag aactctgcca caaactcgct ccaaaagttt ttaaagttat
    31801 acgtatttat tcgagggaaa ataagaaaag cccttcaaat tgggctttct gttcatttga
    31861 aacctgataa atcaagttat agaaggcggt agacggattt gaaccgacga tcaagctttt
    31921 gcagagccgt gccttaccac ttggctatac cgccttaacg tttattatta taccttgaaa
    31981 atgattttca gtcaatagtt ttttcagttt tttgtaccat agcgtgattc gaatgtgatg
    32041 ccaagttttc tatgggaaaa aatttaccaa aaacctactg aaaccccttg aaaaatctag
    32101 ctaaataggg tataatatgg gtaatcattt gtcgtaggtt ttgtctgaaa tattgtccag
    32161 acaaggctca cagcagttaa atcttctgaa aaagtcagat ttagctgctc tttttgtgct
    32221 ttttttcaag attatgagca tttgtaacag aggcttaaag attctgaaaa ttcgtcaaga
    32281 ggacacggtg ataaggggtt tacaaccata tgacgattag aaaagcctga ttgacaaggc
    32341 ttggaactta tttacaaagg agaatcatct tggcaggaca tgacgttcaa tacgggaaac
    32401 atcgtacccg tcgtagtttt tcaagaatca aagaagttct tgacttacca aatttgattg
    32461 aaattcaaac tgactcattc aaagctttcc tagaccacgg tcttaaggaa gtgtttgaag
    32521 atgtattgcc aatttcaaac ttcacagaca caatggagtt ggaatttgtt ggatatgaaa
    32581 tcaaggaacc aaaatacacg ctagaagaag ctcgtatcca cgatgctagc tactcagcac
    32641 caatttttgt aaccttccgt ttgatcaata aagaaacagg cgaaatcaag acccaagaag
    32701 ttttctttgg tgatttccca atcatgacag aaatgggtac tttcatcatc aatggtggtg
    32761 aacgtattat cgtttctcag ttggtccgct caccaggtgt ttactttaac gacaaagtag
    32821 acaaaaatgg taaggtgggc tatggttcaa ctgttatccc taaccgtgga gcttggttgg
    32881 aacttgaaag cgactcaaaa gatatcacct acactcgtat cgaccgtact cgtaagattc
    32941 catttacaac cttggttcgt gctcttggtt tctcaggtga tgatgaaatc tttgatatct
    33001 ttggtgacag cgaattggtt cgcaacactg ttgaaaaaga tatccacaag aatccaatgg
    33061 actctcgtac agacgaagcc ttgaaagaaa tttacgaacg ccttcgtcca ggtgagccta
    33121 agacggctga aagctcacgt agcttgcttg tagctcgctt ctttgaccca cgtcgttatg
    33181 acttggcagc agttggtcgt tacaaaatca ataaaaaact caatgttaaa acacgtttgc
    33241 tcaaccaaac cattgcagag ccattggtag accctgaaac tggagaaatc ttggtagaag
    33301 ctggtacgat tatgactcgt agcgtgattg aaagcattga aagccatttg gatggcgact
    33361 tgaacaagat tgtctacatc ccaaacgatg cagccgttgt gactgagcct gttgttcttc
    33421 aaaaattcaa ggttattgct ccaactgatc cagatcgcgt cgtaacgatc attggtaatg
    33481 ctaacccaga tgacaaggtt cgtacggtga ctcctgcaga tatccttgct gagatgagct
    33541 acttcctcaa cttggctgaa ggacttggcc gtgtagatga tatcgaccac cttggaaatc
    33601 gtcgtatccg tgcggttggt gaattgcttg ccaaccaagt acgtttggga ctttctcgta
    33661 tggaacgtaa tgtccgtgaa cgtatgtctg ttcaggacaa tgaagtcttg acaccacaac
    33721 aaattatcaa tattcgtcct gtaacagctg cagttaaaga attctttggt tcatcacagt
    33781 tgtcacagtt catggaccaa cacaacccgc tttctgagtt gtctcacaaa cgccgtttgt
    33841 cagccttagg acctggtggt ttgactcgtg accgtgccgg atatgaagtg cgtgacgtgc
    33901 actacactca ctatggtcgt atgtgtccaa tcgagacacc tgaaggacct aacatcggtt
    33961 tgatcaataa cttgtcatct tacggacact tgaacaaata tggttttgtt caaacaccat
    34021 accgtaaggt tgaccgtgaa acaggtgttg tcacgaacga aattgtttgg ttgacagctg
    34081 atgaagaaga tgaatatact gtagctcagg ctaactctcg tctgaatgaa gatggaacct
    34141 ttgctgagaa gattgtcatg ggacgtcacc aaggggtcaa ccaagagtat ccagctaata
    34201 ttgttgacta catggacgtt tcaccaaaac aggtagttgc cgttgcgaca gcatgtattc
    34261 ctttcttgga aaacgatgac tccaaccgtg ccctcatggg agccaatatg caacgtcagg
    34321 ctgtgccatt gattaatcct caggcacctt acgttggtac tggtatggaa taccaagcag
    34381 cccacgattc tggtgcggct gtgattgctc agtatgatgg taaagttact tacgcagatg
    34441 ctgacaaggt agaagttcgt cgtgaagatg gttcattgga tgtttaccac atccaaaaat
    34501 tccgtcgttc aaactcaggt actgcttaca accaacgcac tctcgtaaaa gttggtgatg
    34561 tcgttgaaaa aggcgatttc atcgctgacg gaccttctat ggaaaatgga gaaatggcgc
    34621 ttggacaaaa cccaatcgtt gcctacatga cttgggaagg ttacaacttc gaggatgccg
    34681 ttatcatgag cgaacgcttg gtgaaggacg atgtctacac atctgttcac cttgaagaat
    34741 acgaatcaga aacgcgcgat acaaagcttg ggcctgaaga aatcactcgc gaaattccaa
    34801 acgttggtga agatgccctc aaagaccttg acgaaatggg gattatccgt attggtgctg
    34861 aggttaaaga aggtgatatt cttgtaggta aagtaacacc taagggtgag aaagatcttt
    34921 cagctgaaga acgtctcttg cacgctatct ttggagacaa gtctcgtgaa gtgcgtgata
    34981 cttctcttcg tgtaccacac ggtgccgatg gtgtcgttcg tgatgttaag atctttacac
    35041 gtgtaaatgg agatgagttg caatcaggtg ttaacatgtt ggttcgtgtt tacatcgctc
    35101 aaaaacgtaa gattaaggtc ggagataaaa tggccggacg tcacggaaac aaaggggttg
    35161 tctctcgtat cgttcctgta gaagacatgc cttaccttcc agacggaact ccagtcgaca
    35221 tcatgttgaa cccacttggg gtgccatcac gtatgaatat cggtcaggtt atggagcttc
    35281 accttggtat ggcagctcgt actcttggta ttcacattgc gacaccagtc tttgatggag
    35341 caagttctga agatctttgg tcaactgtta aagaagcagg tatggatagc gatgccaaga
    35401 caatccttta cgatggacgt acaggtgaac catttgataa ccgtgtttct gttggagtca
    35461 tgtacatgat caaactccac cacatggttg acgataaatt gcatgcgcgt tcagtcggac
    35521 cttactcaac tgttacccaa caaccactcg gaggtaaagc tcagtttggt ggacaacgtt
    35581 tcggtgagat ggaggtttgg gctcttgaag cctacggtgc gtcaaatgtc cttcaagaaa
    35641 tcttgactta caagtcggac gatatcaacg gacgtttgaa agcctatgaa gctattacaa
    35701 aaggcaaacc aattccaaaa ccaggtgttc cagaatcctt ccgagttctt gtcaaagaat
    35761 tgcaatctct tggtcttgac atgcgtgtcc tagacgaaga tgaccaagaa gtggaacttc
    35821 gcgacttgga tgaaggaatg gacgaagatg tcatccacgt agatgacctt gaaaaagccc
    35881 gcgaaaaagc agcccaagag gctaaagcag cctttgaagc tgaagaagct gagaaagcaa
    35941 caaaagcgga agcaacagaa gaagctgctg aacaagaata agcagttcac ttagaataga
    36001 aagggaagaa atagtggttg atgtaaatcg ttttaaaagt atgcaaatca ccctagcttc
    36061 tccaagtaaa gtccgttcat ggtcttatgg agaagtcaaa aaacctgaaa caatcaatta
    36121 ccgtaccttg aaaccagaac gtgaaggact ctttgatgaa gtgatctttg gtcctacaaa
    36181 agactgggaa tgtgcttgtg gtaagtacaa acgcattcgt tacagaggaa ttgtttgtga
    36241 ccgctgtggg gttgaagtaa cgcgtacgaa agttcgtcgt gagcgtatgg gacatatcga
    36301 gttgaaagct cctgtatctc acatctggta cttcaagggg attccaagcc gtatgggctt
    36361 gacccttgat atgagccctc gtgccctcga ggaagttatc tactttgcgg cttatgtggt
    36421 gattgatcct aaggatacac cacttgagca caagtctatc atgacagagc gcgaataccg
    36481 agagcgcttg cgtgaatatg gttatggttc atttgttgcc aagatgggtg cggaagccat
    36541 ccaagacctt ttgaagcaag tagatcttga aaaagaaatt gctgaactca aagaagaatt
    36601 gaaaacagct actggacaaa aacgtgtcaa agccatccgt cgtttggatg ttttggatgc
    36661 cttttacaag tctggaaaca aacctgaatg gatgattctt aacatccttc cggttatccc
    36721 accagatctt cgtccaatgt tgcagttgga tggtggccgt tttgcctcat ctgacttgaa
    36781 tgacctttac cgccgtgtta tcaaccgtaa caaccgtttg gctcgtttgc ttgagttaaa
    36841 tgcaccaggt atcatcgttc aaaatgagaa gcgtatgctt caagaagcag ttgacgcttt
    36901 gattgacaat ggtcgtcgtg gtcgtccaat cacaggacca ggtagccgtc cattgaaatc
    36961 attgagccac atgcttaaag gtaaacaagg acgcttccgt caaaacttgc tcggtaaacg
    37021 tgttgacttc tcaggacgtt ccgttatcgc cgttggtcca actcttaaga tgtaccaatg
    37081 tggtgtgcca cgtgaaatgg cgattgaact ctttaaacca tttgtcatgc gtgaaatcgt
    37141 tgcccgtgat atcgtgcaaa acgtcaaagc agctaaacgc ttggtggaac gcggagatga
    37201 gcgtatctgg gatatccttg aagaagtgat taaagaacac ccagtgcttt tgaaccgcgc
    37261 accgaccctt caccgtttgg gtatccaagc cttcgagcca gtcttgattg atggtaaggc
    37321 tcttcgcttg cacccacttg tctgtgaagc ctacaatgct gactttgacg gggaccaaat
    37381 ggccatccac gtaccacttt cagaagaagc acaagcagaa gctcgtatcc tcatgctagc
    37441 tgctgagcac atcttgaacc cgaaagatgg gaaaccggta gttactccat ctcaggacat
    37501 ggttttgggt aactactact tgaccatgga agaagctggt cgcgaaggtg aaggaatggt
    37561 cttcaaagac cgtgacgaag cggttatggc ttaccgcaat ggttatgttc acctccactc
    37621 acgtgttggt atcgcaacag acagcctcaa caagccttgg acagaagagc aaagacataa
    37681 ggtcttgctt acaacagttg gtaaaattct cttcaacgat atcatgccag aggggctacc
    37741 atacttgcaa gaaccaaaca atgccaactt gacagaaggt gttccagcta aatacttctt
    37801 gccacttggt ggagctatca aggaagctat cagcaatctt gagctcaacc ctccattcaa
    37861 gaagaaaaac ctcggaaata tcatcgctga aatcttcaaa cgtttccgta cgacagaaac
    37921 ttctgcccta cttgaccgca tgaagaacct cggttaccac cactcaactc ttgcaggatt
    37981 gacagtgggt attgccgata tcccagttgt tgatgacaag gctgaaatca ttgaagaatc
    38041 acacaaacgt gtcgaacaaa tcaccaaaca attccgtcgt ggtatgatca cagacgacga
    38101 gcgttacaat gctgttacag ctgaatggcg tgctgcccgt gaaaaacttg agaaacgctt
    38161 gattgctaat caagatccta agaacccaat cgttatgatg atggactctg gagcccgtgg
    38221 taacatctca aacttctcac agcttgccgg tatgcgtggt ctgatggctg ctccgaatgg
    38281 acgtatcatg gaattgccaa tcctttcaaa cttccgcgaa ggtttgtcgg tattggaaat
    38341 gttcttctca actcacggtg ctcgtaaagg tatgaccgat acggccctta agacagccga
    38401 ctcaggttac ttgactcgtc gtttggtcga cgttgcccaa gacgttatca tccgtgagga
    38461 cgactgtgga actgaccgtg gtctcttgat ccgttctatc gcagaaggaa aagagatgat
    38521 cgagtctctc gaagagcgtc tcaacggtcg ttacactaag aaaactgtta aacatccaga
    38581 aactggtgca gtgattattg gtccaaatga attgattaca gaagacaagg cgcgtgaaat
    38641 tgtcaatgct ggtgtggaag aagtgactat ccgttctgta tttacatgta acactcgtca
    38701 cggtgtctgc cgtcactgtt acggtatcaa cttggcgact ggtgatgcgg ttgaagttgg
    38761 tgaagcagtt ggtacaatcg ctgcccaatc tatcggggaa cctggtacac agcttacaat
    38821 gcgtaccttc cacacaggtg gggttgcctc aaataccgat atcactcagg gtcttcctcg
    38881 tgtccaagaa atctttgaag cccgcaatcc taaaggggaa gcggttatta cagaggttaa
    38941 aggacaagtt actgctatcg aagaagatgc atcaactcgt accaagaaag tctttgttaa
    39001 gggtgaaact ggcgaaggtg aatatgtcgt tccatttaca gctcgtatgc gtgtcgaagt
    39061 tgggggccaa gtagcgcgtg gtgctgctct gacagaaggt tctatccaac caaaacgtct
    39121 ccttgcagtt cgtgatgtct tgtcagttga aacgtacctt ctcggtgaag tacaaaaagt
    39181 ttaccgtagc caaggggtag aaatcggtga caaacacatc gaggtaatgg ttcgtcaaat
    39241 gatccgtaaa gtccgtgtca tggatccagg tgatacagat cttctcatgg gtaccctcat
    39301 ggatatcaat gactttacag atgccaacaa agatgtcctt atcgcaggtg gagttccagc
    39361 gacaggtcgc ccagtcctta tgggaattac caaagcctca cttgaaacaa acagtttctt
    39421 gtcagcggct tccttccagg aaacaactcg tgtccttact gacgcagcta tccgtggtaa
    39481 gaaagaccat ctccttggac ttaaagaaaa tgttatcatc ggtaagatca tcccagctgg
    39541 tactggtatg gcccgttacc gtaaccttga accacatgct gtcaacgaag aagaatacct
    39601 taatcctcca gtagaggaag aaggaaatga agaaacaaca gaagtagttg tggatactgc
    39661 cgttgaaact gtggaagaaa cagtagaata agagagaatg agagaacccg agggttctct
    39721 cattctctct tctgaaaact ttctccattt ttccacgaaa tgtggtaaaa taaaagaaag
    39781 aagctgacaa aggagacggg tatggaacaa acattcttta tcatcaaacc agatggtgta
    39841 aaaagagggc tagtgggtga agtgttaaag cgcatcgaac aacgtggatt tacaatcgaa
    39901 aaattggagt ttcgttcaca ggtttcagaa gagttgattg accagcacta tcaggacttg
    39961 gttggtcaga gtttttaccc accgattcgt gaattcatga cttcaggtcc agttcttgtg
    40021 ggtgtcattt ctggtcccaa agtaatcgaa acttggcgga ccatgatggg tgcaactcgt
    40081 ccagaagaag ctttaccagg cactattcga ggtgattttg caaaagctgc tggagaaaat
    40141 gagattatcc aaaatgttgt acatggttca gattcagaag agtcagctaa gcgagaaatt
    40201 gctctttggt tttaagagtg gattggctca atcaattggt taaaagctca tttgaataga
    40261 aagtatagtc aattagttta agacatgacg catgatatca aactttttag tttttgatat
    40321 ggtgcgtttt ttgattaagt gactattagt ttgtctcgct ccgttaggtg cgagacaaaa
    40381 aaaacacccg ctatgcgggt gtgcgtcgaa ggttatacca aaaaaactcc aaacgcgata
    40441 caataaaggt gttcaatcca attgtaaagc gaaaggagaa aaatatggca caaaaggttc
    40501 ttttatcctg ttcttgtttc aattgactat atttctatac tttttcttcc tttctctgtg
    40561 aaaatcgcaa gtttttccca ccttttctca atactgaaac aacatctttc cagaacttca
    40621 ataatttctt tttgtgttaa atcattattt aactaaatct ttggaggcaa tacgttttca
    40681 aagcgacttt tttaccatag gttttgagcc ttcaacacag attactaagc caaaaatgct
    40741 ctaaattttt gaaattctaa caaattccac tcaactttat catcatcttt gactttcaca
    40801 atatcttcct caaaataaca tggaataaag atagttttct tttgaaacgg ttgtaggagg
    40861 aaaatctctc ctacactatt attgattctg agaggaaatt gcaaaatatc atctaccaaa
    40921 ttttcaatta ttaagatttt ttgcagttta tctgaattag aatcgcaagg cttctcaata
    40981 atataattgt cgaatttttt cattctaact tcctctctac tatttcttcc tttatcaaga
    41041 aaaagttacc tcaatattaa taaagtacaa ttctaaatta actccaattc ttgattcatg
    41101 ataatatttc agtaactcat cgtgcaatta aaaacaagga tttttatttc agacgatcca
    41161 tcgtgaacac ttcatcagcc atctcccaaa ttgccggatt atgtgttgcg ataatgatta
    41221 gcctattatc atctcgaaga gatagcaaaa tctccataat caactgagaa gttgctgggt
    41281 ctattgaagc tgttggctca tctgccagaa taaagggtgg attctttaag ataacttttg
    41341 ccaaggcaac ccgttgcgat tctccgcccg ataactcaaa gatgcgctta tctaggttaa
    41401 gataagccag gccgacctgt tctaaagcct gcttctgcct caaccgctgt tccgaccgac
    41461 tcaacttttg accaatgaga cctagcttaa ggttttcttc aatactttgg ttttcaatta
    41521 agccaaagtt ctggaagagg tagcccaatt cgtgacggaa aaaatcactc gatttataat
    41581 tggccaagtc tttacctcgg taaaaaatcg tcccatcata aggttctaat ttcccaatca
    41641 tgttcatcaa ggttgttttt ccgctaccac ttgaaccaat taaggcatag acttttccag
    41701 cctcaaatgt cattgaaaga ttcgaaaata actctcgttc tccaaaagat ttactcacct
    41761 gtttaagttc aatcatatta acctcccttc aaaacaagca tggacatctt gttttctttc
    41821 tgcatttgga catgtaactg taaaagagat agaccagtaa agagtaacaa gactaagaaa
    41881 gcaactccta tctctacctg aagaaataca ctcgcaacaa atcccagtaa aaacacaccc
    41941 agttgagcaa agagataagt gcgatggatt tctaagaacc tgagacctgc aatgcgtttg
    42001 ataaaaatgg cacgtctaaa ttcttcaaag tagagcctat tcatagtgtt aaacagcaag
    42061 attgaagttg caatcccaag cacagctcct gctagcatta cccaacgttc cctctggata
    42121 ttatccaata atgtgatgta gttgtggtaa cctgtttgca tttctgagac ccaattttca
    42181 atgccttgtc tctggataag ctcctgggca tcagacaatt gattaaagag aacgtagttc
    42241 tgtactgcgt ctatccaaaa caaaatggac tgtggaccag ttgattgggg tgttataaca
    42301 atgatgattg gatctttcaa aaactgctgg taagaaatag gggtcgtatt atacacaaaa
    42361 cgatcctgac ctgattctaa ataacctacc gtagcagtca tttgctgtcg ttcatcttga
    42421 ctagacatgc gactggttaa gtcgtcttca aaaacagatt tataatgttc ttcctctgaa
    42481 cggaggtgtt caggcagcaa taagacaaac tcccctacat taaggtgatt catcttttgc
    42541 ttaatagttg tatctacagg aatgttttga cgctccaagt aatgcggtgt gacgataagg
    42601 acattgccat tcgggctgta atcgtgccat tctgtagagg ttgtcaagtt tttggaggaa
    42661 gccatgccat tttgcaaagt acggtcaatt aactggtgtc tagataagaa agccttttgt
    42721 tctgaaacag ccagatccat caattgatac caagttctga gtttcctttg agcttgttca
    42781 tcaaaaccag gactcgttcc ttcacggctg attgataggg taatcagttg tctttcctga
    42841 ctccaaacct cttgtccaat ccgatgctgt tgccaggctt gggaatactt taagctactc
    42901 cctattccca gcgttacaat aataatcgct aacagttgac cgattaaaat caaactaatg
    42961 attcctctga caggcacttg cccttttata atctgcatca ggtgtatctt ttttatccca
    43021 actgcgaaga gttgagcgaa aaacagggag atcgacaaca agatgagatt ataactgagc
    43081 aagcctgctc ctatggtcat tagggattgc gttggaagcg acagaatttt ttgcataaga
    43141 atggcgagca cgccagctaa actgaaacca acagctatcc ctttcaaatc ctcaccaact
    43201 ggtctaagga aaatggacca ccgtttctct cctgaaatga ggcgaatgcc cgatgaccgt
    43261 aattggctaa tttgactaat taaagtcagt gctacaaagg ttaagatgaa aatcaataga
    43321 ctgattaact gaaatccgtt actaaagata gccattaacg tagatagttt agatggaatt
    43381 gtcaggtgca tgttagtcaa gccaagttga cttagctctt cccttagcaa gtgaatatct
    43441 aggtgtccat cgaatacaaa atagtttgtt tcaacactac tactttgagc atcttctaga
    43501 tttttttcct gaagcccatc aggcaacttt ccgtccccaa aggtcgtata agaaaaaact
    43561 gtagtacctt ctgagttagg atcttggtgt tgaatcgcaa taaagctatc tgtttcttct
    43621 gctagttttt ccaagcgtgt agcaacatgc tgaaaagttg tttcagggga agaatcacgt
    43681 acaacaacgt tggggtaata atgggagaca tatgtatcag tccaaatggt aaatacccaa
    43741 acaaagaaca aactagcaag caggttggat atgagtataa ataatttttt catagtgcat
    43801 tccttattct aaaacagagg gcagaaatac tcctgccctc tataaactaa caagcttact
    43861 gaattattga taaaagaatc ttcttcaatt attctttacc atcccgcatc aaatgtaact
    43921 tgctccccaa aatttgtatt aacaaacgca taggccgcac tacgtgctcc tgcataaact
    43981 gttttttgat tgttacgtcc attacttcca acataggccc agtgatactg tgaaccatga
    44041 taataattcg aaaatgctcc ccaattattt ggatcatgat ggcctccata ggtccactcg
    44101 ccaccacggt gagaaactgc caaaacagga agagccaaac taaatgccaa aacggcaagg
    44161 gatgatgcaa ctacttttct aaattttaac atattattac tcctctgaat gaaatattat
    44221 gaaaatgagc gaaatgcaac tatatatttt aattagaaat ctcagtctga attatagtat
    44281 cctatttttt cctcctttct aactgcacgt tcctttctac aggcagagac ctaattttat
    44341 aaaccaatct taaatacttt agattttgta actcataatt ttcaacagtt ggttagctat
    44401 gaaagcattt tatcaaacat ctccattctt atatctatct ggtattgtta caagctctca
    44461 tcagaatacc tttctctaaa tagttgaatt ttaaagtaat ataaaatcaa tcagccttcc
    44521 caacatcaag accattggac ttcttttgcg attgcactcg aatctccaat tgtttattct
    44581 tctgaataaa ctgttggtaa ggaattgtat tactaaacat aaaaacacct agcaatgcaa
    44641 atgtaactaa ttttttaatt ccacgttttt tccatgcaat gaaacccctt tctttttatt
    44701 ctaacagata tattttattt agtcaagtgt ttttat
//
LOCUS       DAVMBH010000012        43520 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVMBH010000012 DAVMBH010000000
VERSION     DAVMBH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.012"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(584..1834)
                     /gene="ilvA"
                     /locus_tag="VYP30_000772"
     CDS             complement(584..1834)
                     /gene="ilvA"
                     /locus_tag="VYP30_000772"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1807804.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(1884..2240)
                     /locus_tag="VYP30_000773"
     CDS             complement(1884..2240)
                     /locus_tag="VYP30_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1807805.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(2478..2714)
                     /locus_tag="VYP30_000774"
     CDS             complement(2478..2714)
                     /locus_tag="VYP30_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807806.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(2821..3843)
                     /gene="ilvC"
                     /locus_tag="VYP30_000775"
     CDS             complement(2821..3843)
                     /gene="ilvC"
                     /locus_tag="VYP30_000775"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1807807.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDAYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(3909..4385)
                     /gene="ilvN"
                     /locus_tag="VYP30_000776"
     CDS             complement(3909..4385)
                     /gene="ilvN"
                     /locus_tag="VYP30_000776"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1807808.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4378..6078)
                     /locus_tag="VYP30_000777"
     CDS             complement(4378..6078)
                     /locus_tag="VYP30_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1807809.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6278..7945)
                     /locus_tag="VYP30_000778"
     CDS             complement(6278..7945)
                     /locus_tag="VYP30_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1807810.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(7948..8313)
                     /locus_tag="VYP30_000779"
     CDS             complement(7948..8313)
                     /locus_tag="VYP30_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1807811.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(8470..8658)
                     /locus_tag="VYP30_000780"
     CDS             complement(8470..8658)
                     /locus_tag="VYP30_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1807812.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(8774..9259)
                     /locus_tag="VYP30_000781"
     CDS             complement(8774..9259)
                     /locus_tag="VYP30_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1807813.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(9528..11072)
                     /locus_tag="VYP30_000782"
     CDS             complement(9528..11072)
                     /locus_tag="VYP30_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1807814.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            11285..11587
                     /gene="gatC"
                     /locus_tag="VYP30_000783"
     CDS             11285..11587
                     /gene="gatC"
                     /locus_tag="VYP30_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1807815.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            11587..13053
                     /gene="gatA"
                     /locus_tag="VYP30_000784"
     CDS             11587..13053
                     /gene="gatA"
                     /locus_tag="VYP30_000784"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1807816.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQTTLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13053..14495
                     /gene="gatB"
                     /locus_tag="VYP30_000785"
     CDS             13053..14495
                     /gene="gatB"
                     /locus_tag="VYP30_000785"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1807817.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            14624..15184
                     /gene="efp"
                     /locus_tag="VYP30_000786"
     CDS             14624..15184
                     /gene="efp"
                     /locus_tag="VYP30_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1807818.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15206..15595
                     /locus_tag="VYP30_000787"
     CDS             15206..15595
                     /locus_tag="VYP30_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1807819.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            15588..16010
                     /gene="nusB"
                     /locus_tag="VYP30_000788"
     CDS             15588..16010
                     /gene="nusB"
                     /locus_tag="VYP30_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1807820.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16060..16296)
                     /locus_tag="VYP30_000789"
     CDS             complement(16060..16296)
                     /locus_tag="VYP30_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1807821.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(16309..16782)
                     /locus_tag="VYP30_000790"
     CDS             complement(16309..16782)
                     /locus_tag="VYP30_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807822.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(16800..16985)
                     /gene="briC"
                     /locus_tag="VYP30_000791"
     CDS             complement(16800..16985)
                     /gene="briC"
                     /locus_tag="VYP30_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1807823.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(17144..17911)
                     /locus_tag="VYP30_000792"
     CDS             complement(17144..17911)
                     /locus_tag="VYP30_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1807824.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(17908..18774)
                     /locus_tag="VYP30_000793"
     CDS             complement(17908..18774)
                     /locus_tag="VYP30_000793"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1807825.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(18811..20178)
                     /gene="accC"
                     /locus_tag="VYP30_000794"
     CDS             complement(18811..20178)
                     /gene="accC"
                     /locus_tag="VYP30_000794"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1807826.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(20190..20612)
                     /gene="fabZ"
                     /locus_tag="VYP30_000795"
     CDS             complement(20190..20612)
                     /gene="fabZ"
                     /locus_tag="VYP30_000795"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1807827.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(20609..21094)
                     /locus_tag="VYP30_000796"
     CDS             complement(20609..21094)
                     /locus_tag="VYP30_000796"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1807828.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(21097..22332)
                     /gene="fabF"
                     /locus_tag="VYP30_000797"
     CDS             complement(21097..22332)
                     /gene="fabF"
                     /locus_tag="VYP30_000797"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1807829.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(22354..23085)
                     /gene="fabG"
                     /locus_tag="VYP30_000798"
     CDS             complement(22354..23085)
                     /gene="fabG"
                     /locus_tag="VYP30_000798"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1807830.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(23119..24039)
                     /gene="fabD"
                     /locus_tag="VYP30_000799"
     CDS             complement(23119..24039)
                     /gene="fabD"
                     /locus_tag="VYP30_000799"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1807831.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(24032..25006)
                     /gene="fabK"
                     /locus_tag="VYP30_000800"
     CDS             complement(24032..25006)
                     /gene="fabK"
                     /locus_tag="VYP30_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1807832.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(25125..25349)
                     /locus_tag="VYP30_000801"
     CDS             complement(25125..25349)
                     /locus_tag="VYP30_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1807833.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(25409..26383)
                     /locus_tag="VYP30_000802"
     CDS             complement(25409..26383)
                     /locus_tag="VYP30_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1807834.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(26383..26817)
                     /locus_tag="VYP30_000803"
     CDS             complement(26383..26817)
                     /locus_tag="VYP30_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1807835.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(26911..27696)
                     /locus_tag="VYP30_000804"
     CDS             complement(26911..27696)
                     /locus_tag="VYP30_000804"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1807836.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            28021..29385
                     /locus_tag="VYP30_000805"
     CDS             28021..29385
                     /locus_tag="VYP30_000805"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1807837.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEDNEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREIGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            29388..29759
                     /locus_tag="VYP30_000806"
     CDS             29388..29759
                     /locus_tag="VYP30_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1807838.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            29973..31247
                     /gene="serS"
                     /locus_tag="VYP30_000807"
     CDS             29973..31247
                     /gene="serS"
                     /locus_tag="VYP30_000807"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1807839.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(31272..32171)
                     /locus_tag="VYP30_000808"
     CDS             complement(31272..32171)
                     /locus_tag="VYP30_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1807840.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEMAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(32281..32829)
                     /locus_tag="VYP30_000809"
     CDS             complement(32281..32829)
                     /locus_tag="VYP30_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1807841.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(33047..34369)
                     /locus_tag="VYP30_000810"
     CDS             complement(33047..34369)
                     /locus_tag="VYP30_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1807842.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITSLVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(34460..34548)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(34712..37048)
                     /locus_tag="VYP30_000811"
     CDS             complement(34712..37048)
                     /locus_tag="VYP30_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1807843.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(37152..37700)
                     /locus_tag="VYP30_000812"
     CDS             complement(37152..37700)
                     /locus_tag="VYP30_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1807844.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(37697..37999)
                     /gene="zapA"
                     /locus_tag="VYP30_000813"
     CDS             complement(37697..37999)
                     /gene="zapA"
                     /locus_tag="VYP30_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1807845.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            38086..38967
                     /locus_tag="VYP30_000814"
     CDS             38086..38967
                     /locus_tag="VYP30_000814"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1807846.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQVLLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            38971..39585
                     /gene="lepB"
                     /locus_tag="VYP30_000815"
     CDS             38971..39585
                     /gene="lepB"
                     /locus_tag="VYP30_000815"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1807847.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            39713..42079
                     /locus_tag="VYP30_000816"
     CDS             39713..42079
                     /locus_tag="VYP30_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1807848.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(42127..43410)
                     /locus_tag="VYP30_000817"
     CDS             complement(42127..43410)
                     /locus_tag="VYP30_000817"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1807849.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        12660 a        10004 c         8253 g        12603 t
ORIGIN      
        1 ctacaccata aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat
       61 tattcaagtt cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta
      121 agaactgaag atgatagttc taacctttag aaatccaagc cttcactagc tcaaaaactc
      181 ctatctttct tcctcaataa atcatctgag agataggtat tccttatgtc cttcaaattc
      241 atcactcctt tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat
      301 ccttaataga gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat
      361 agtatatttg tcaacaaaaa gaaatcaaat cataccttat actcaatgaa aatcaaagag
      421 caaactagga agctagccgc aagttgctca aaacactgtt ttgaggttgc agatagagct
      481 aacgtggttt gaagagattt tcgaagagta ttaaagacag tgtgactatg cttgtcaata
      541 gataggaaat caaaatgaag gtatgatatt tttttattag tcctcagaca agcatattat
      601 aaagcgtttc attaccattt aagttaatat aagctggatc aaaaccttcc attctacgaa
      661 tcaaacctgc ataatcatgc ttatctgcta aagcgatccc aattaatact gggcctgttc
      721 ccttgctagc tcgtttgata tactcaaaac gtgtgatatc atcatttggc cccaggatat
      781 catttacaaa ctcacgcaaa gctcctggac gttgtgggaa attgaccaca aagtaatgtt
      841 tgataccatc ataaatcaag gcacgctctt ccatttctgg catacggttg atatcattat
      901 ttcctccaga aatgatacaa caaatggttt tccccttaat atattcagct aaaacctcta
      961 aagaggcgat actagccgct ccagcaggtt ctgcgactat cccttgctta gagtaaaggt
     1021 caatcaaggt ttcagaaatc aatccctcat cgacacctac caaagtttta atatgttgac
     1081 gagttgcttc ataggtcaac tgacctacct tttgcacagc aatcccatca gcaaatttat
     1141 caatttcctt gagttttact ggacctccag cctcaaaggc agctttcatg gaacgcgctc
     1201 cattcgcctc tactccgata acctcaatct ctggacttgt ttccttgata taggtagaaa
     1261 ccccggcaat gagaccgcca ccaccaacag gaaccaagac agcatcaaaa tcaatcgatt
     1321 cttttcgagc ttcttctaaa atctcataag caactgttcc ttgacctgct tgaacatgag
     1381 catcatcaaa aggatcaata aaggtacgat tttcagagac tgtaaattct tgagctgctt
     1441 tggctgaggc atcaaaggta tctccaacta gtttaatagt tacaaaatcc ccaccaaaaa
     1501 agcgaacctg accaatcttt tgttgtggcg tagtaatggg cataaagata gtagcaggaa
     1561 ttttcatttc attacaagta taggctactc cctgcgcatg atttcccgca gaagcgcaga
     1621 ctaccccacg ttcacgttct tccttgctga gctgggaaat ggcataatag gcaccacgaa
     1681 ttttaaagga gcgaacacgc tgggcatttt cttttttcaa ataaatctta gcaccatact
     1741 tctccgataa ataatgatcg taatccagtg gagtattcac aaccacaccg ttcaagacct
     1801 tgtgagcctt gattatatct tttgaactta acatataaaa cctctttttc tataaaaaac
     1861 agtcactaat gactgttttt tagttattca tctccgaaaa cttcagtaac actttcatgg
     1921 tatttatgag ccatacgaat cgaaaactct ttaggaagtt cataacgatt tgtggaaatc
     1981 caatcatata accattctac caaactttct tcactatcat tacgatggaa gataaaatag
     2041 tttaaaattt ctttatattc tacatcattc aaatccaacg tgtctacaaa ttgactacga
     2101 ggaacaaaat tagaatctaa ttttcttagt tgatctgtca attctcccaa ttgtaaatcc
     2161 aactgaaaaa atagtttttg cagttgccta tcagtttcat cacatcctgt cttgatagaa
     2221 aacaaattgg taatattcat atgatttcaa cccctaaata agtacatcta atatcccacg
     2281 aatagctgaa gctaaagttt tcgcagtcca gtcatttaaa cccgattctt tcaatccaga
     2341 tgcaataatt tgctctattt gatataaacc gccatctatc gtctcattta ttctgcgaag
     2401 aggaccttca atataggata aagcttctcc gaatctaaca gctgatttag gtcctaatga
     2461 tttaccaact atatttgtta atgtttttta tttctcaaaa tccatttcgc tatataacga
     2521 gcagatttag tcgcaccagc tctctcaaac ggagaatgaa tttcaagacc ttcttctcta
     2581 gctatttgtg ccaatttgaa gaattgttca aagttcatat gcaacctacc atcttcaaaa
     2641 ttagcatcat cataaatgtt aattacagca ttttcatcat acgaccaatc tgctttattt
     2701 tggtctgcta gcactattac cgacggtgta attacattat acaactagaa ccaataataa
     2761 cgatgcaatt tttctcataa tctttttcat aaaatcatct ccagcgctat atatttctaa
     2821 ttagttatag attttgaatg catcatcgtc gtttttacca acgaatggca ttgctttacg
     2881 caattctgca ccaacttttt caatttcaag gttagctgct tgttcacggt aagcagtcaa
     2941 ttttggacgt ccagctttat agtcatttac aaagtcattt gcaaatttac cattttggat
     3001 gtctgccaag acagccttca tattttcttt aacttgttca gtgattacac gtggacctga
     3061 tacatagtca ccgtattcag cagtgtttga aatagattga cgcattttct tgaatccacc
     3121 ttcgtagatc aagtcaacga tcaatttcat ttcgtgaaga acttcaaagt aagccaattc
     3181 tggagcgtaa cctgcttctg tcaagacttc gaaacctgct tcgataaggg cagtcaaacc
     3241 accacaaagt acagcttgtt caccaaacaa atcttcttca gtttcttctt tgtaagttgt
     3301 ttcaagaaga cctacacgag ccgctccaac acctttacac cagtccatag caatgttttt
     3361 agcatttcct gttgcatctt ggtatactgc ataaagagct ggaacaccaa atccttcttc
     3421 gtaagtacga cgtaccaagt gtcctggtcc tttaggagca cacatgaaga catctacatc
     3481 cgcaggaact ttgataaatt caaagtggat gttgaaacca tgggcaaatc caactgcgtt
     3541 tccagcttcc aagtttggag cgatttctgc ttcgtacaat tcttgttgaa tttcgtctgg
     3601 cgccaagatc atgataacat cagccaactt agtagcttct gctactgtgt aagcatcaaa
     3661 tccatcttct tttgctttat caaaagattt acctggacgt acaccgataa taacgtcacg
     3721 acctgaatca cgcaagtttt gagcatgcgc atgcccttgt gaaccataac cgataacggc
     3781 gattttttta ccgtcaagtg ctgctacttt aacatctttt tcatattcca tttgaactgt
     3841 catagctttt ctctcttttc tattatttat tgccttttag gctggtttaa taaatttaag
     3901 ttggattttt aatcgcgggt aaatccagtt gcacccgttc gagcaatatt gcgaataccg
     3961 tatgggcgaa tgactcgcaa tagggcttcg ctcttttctg catttcccgt catctgaatg
     4021 gtaatcgagc ttggcgctac gtctactact gttgcacgga aaggttgaat aatcgctaaa
     4081 atctcagctc tcttctcagc tggcgctgac atcttaacca aaatcacctc gcgctccaaa
     4141 tgaggcttgt ctgtaatatc tcgaatgcga atcacatcaa tctgacgatt gagctgtttg
     4201 atgatttgct ccacttcatc atgagaagca acatcaataa taatagtgat acgcgataca
     4261 ttcggatctt ctgttgctcc aacagagatg ctttcaatat taacctgacg acgagatagg
     4321 acacctgtaa agcgattgag gactcctgaa cgattttgta gttttgctgt taacattcta
     4381 cgcatggaac tgcaccccca acatctcatg attactctta ccagccggta ccattggtaa
     4441 cacctgttcc ttacgagaaa tatctacctc aattagcata ggaacatcct cagtgatgac
     4501 ttcaaggtct tgagccaagg tctcaggatt gtcaaactta tagtttttaa taccataagc
     4561 ctgcgccatc aattggaaat caggaagggt atcaaagacc gactctgatg ttctgccttc
     4621 atagaaggat tcctgccact ggcgaaccat tccaagtgaa tgattgttca gcataaccac
     4681 cttgattggc accttgtaaa tattcaaaat agccaactcc tggttggtca tttggaaacc
     4741 accatcccca acaaacaaga ctacttcctt atctgggtta gcaattttag caccgattgc
     4801 tgctggaatt ccaaagccca ttgttcccaa accacctgaa gtcactaact gacgttcatt
     4861 ttggtaggga taatactgag ctgtccacat ttggtgttga ccaacgtctg ttaccacaat
     4921 ggcatctcca ttcgtcaatt caccaattcg ttcaataact gcttgcggtt gaaccacacg
     4981 ctctttctta tcataagaac gaacacgatt cttgtcttta gtgactttct caatccactt
     5041 ttcagtgttg ttgtgaactg ttggttctgc tagcaacatt tgcaaggcct tcttagcatc
     5101 tccaactaca ggaatgtctg cactgataat cttgccaatc tcagctgggt caatatcaat
     5161 gtgggcaacc ttagcattct tagcgaaagt cttaggattc cccgtcaaac ggtcatcgaa
     5221 acgagaacca atactaatca taaagtccgc ttccgtcata gcaatatttg ctgcgaatga
     5281 cccgtgcatg cctcccattc caagaaagag tgggtgactc gttgcaatcg ttccttgtcc
     5341 caaaagactg gttaccactg gaatttgata gcgttctgca aattcattta gttccgtagc
     5401 agcctcagca taactaattc caccaccagc taacaagact ggctttttag ccttggacaa
     5461 ttgcttcaag attttcttga tttgcatatc attcggctca agagtcggct gataacttgg
     5521 taaattcact tctggtgaat aaatgaagtc tgtttctaaa gcagatatgt cttttggtag
     5581 gtcaattaca actggccctg gacggcctgt agttgcgata tggacagctt ccgtaatgat
     5641 acgcggaata tcagctgtct cacgaacttg gtaattgtac ttagtgattg gcatggtaat
     5701 tcccacgatg tctgcctcct gaaaggcatc cttcccaatc cctgctcgcg ccacctgacc
     5761 tgtaaagacc aaaaggggaa cgctatcgct catggcatcc gcaatccctg taatggcatt
     5821 tgttgctcct ggtccactag tgacgacggc aacacccaac tttccagttg atttggcata
     5881 accttcagct tcatgcaaac aaccttgctc atggcgccct agaatgtggc gaatgccttt
     5941 aaaattatat atcgcatcat aaaaaggcaa aaccgcacca ccaggataac caaagatggt
     6001 atcaactcct aaatcacgaa gtgtttccaa aactaggtcc gaccccgtct taggagattc
     6061 taaactgatt ttctccatta ttcccctttc tttcctctta aaaataactt gttactatca
     6121 taccattttt tcaaaatttt tcaagataaa agaagaaatt ttctgaattt tctattttaa
     6181 cgtttattta tgaatgttat ttttgttttt attaaaaaga taccgatttc atttactaaa
     6241 aagaaaaaag aactgatttc tcagtccttc attaatctta ttccacacta aataggtatg
     6301 ggtaaacagg ttgttgacct tggtgaatct cgacttcaac gtcttcgaat tcttctacga
     6361 tttcttgagc gatttcattg gcaagttctt cgcttccgtc ttcacctaca tagaaggtta
     6421 cgatttcact gtcttcatcc aacatatgtt tcaaggtttc agtcaatgtt tggtgcatat
     6481 cagggtttga cacaagaatt tttccatcca ccatacctaa attatcgttt tcatggattt
     6541 ctaagccatc gatcgttgta tcacgcacgg ctgttgtgac gcttccgcta acgacatcgc
     6601 taagagcagc tgtcatacgc tcttggtttt cttcaatgga cttgcttgga tcaaaggcaa
     6661 gaagacttgt cataccttga ggaagagtgc gagcctctac cactaccgct ggttgctcca
     6721 aaacttctgc cgcagattga gctgccatga agatgttctt gttgtttggc aagaagatga
     6781 tgttacgggc attaacctgt tcaacagcct tgataaagtc ttctgttgaa gggttcatgg
     6841 tttgaccgcc ttcgataaca taatccacgc cttgagaaca gaagatatct gctagacctt
     6901 taccagccac cacagcaatc aaagcatact ctttttcttc agccgacttg ataacttgag
     6961 tagcttcttt ctcaacctgt gcttcgtgtt ggttacgcat attgtcaact tttaccttga
     7021 ccaagctacc atatttgaga ccttcttgca taacaagtcc tggatcttct gtatgaacat
     7081 ggactttgac aatttcatca tcgttaacaa caaggagaga atctccaagc tcatccaagt
     7141 agttacggaa ttcatcgtag tcaaaatctt tagcataggt tggaccttgc ttaagagcta
     7201 ccatgatttc agtacagtaa ccaaacgtga tgtcctcagt cgctacgtga ccagctacag
     7261 acttatgatg ctctacattg atcatctcac tcatgttggc aggagtcgct acaaagtcct
     7321 cagatgcaat atattcgcca gtaagggctg aaaggaaacc ttcgtagatg aagaccaatc
     7381 cttgaccacc tgagtccaca acgccaactt ctttcaatac tggaagcatg tctggtgttt
     7441 tagctagagc tgttttagca ccttccaagg ctgcgcgcat gacttcaaca gcgtcatctg
     7501 tttgctcagc ttttttctta gcaccgatag cagctccacg agaaactgtt aaaatcgttc
     7561 cttcaacagg tttcatcact gccttatagg caacttccac acctgattgg aaggccagag
     7621 ccaagtcttg acctgttaac tcgtctttat ccttgatagc ttgggaaaat ccacggaaaa
     7681 gctgagacgt aatcactcct gagttcccac gcgcacccat caaaagccct ttggcaagaa
     7741 tgctcgctac ttctccaact gtagaagctg gcttgtctgc aacttcttta gcaccatttt
     7801 caatggtcat tcccatattt gtcccagtat ctccatctgg aactggaaag acgtttaatg
     7861 aattgacata ttcagcttgc ttattcaagc gagttgatgc agcctgcacc atttcttgaa
     7921 ataagctagt agtaattttt gacacggtta ttctcctaca actttgatat tttgaatgta
     7981 gacatttaca gtctgagcag taattccaag ctggttttcc aagctaaagg caacacgctc
     8041 ttgaatgttt tttgacactt cactaatctt tgttccgtag cttaacacgg tatatacatc
     8101 aactgcaata ctgccatctt cggctgcctt tacgacgaca cctttagaat aattttcctt
     8161 acctagcagg gcttggaaat tatctttgag ggcattttta ctagccatac cgaccacacc
     8221 aaaaatctca gttgctgctc cacctacgac ggttgcaatc acttcatctg ttagttcgat
     8281 ttgaccatct tttgtattaa tttttacagt catccttttt acctcaacta gttgatactc
     8341 tattttatca tatttcagcc caagtgtaaa agcagaatga tgtatcagcg gatatttact
     8401 ctatttttca aacgatgtta tacccacaat aaaagaaaaa agaccctaag gtctcctttg
     8461 cttttattat taaacgcgtt caactttacc tgatttcaaa gcacgagctg aagcccaaac
     8521 ttttttaggt ttaccatcga taagaacagt aactttttga aggtttggtt ttacggcacg
     8581 ttttgtttgg ttcatcgcgt gtgaacggtt gtttcctgat acagtcttac gacctgtaaa
     8641 gtaacatact ttagccattg tgttttcctc ctattagatc taatatagcg gatgtgctag
     8701 caccacatac cgtactatgt tatcacactt tcttgttttt tgcaagggaa ttggaagatt
     8761 ttttatttgt gtcttaaatc aggtcttgcg tgacattttc tgctctccac atgccattgt
     8821 tgattaacag aacaccagaa ttaaaattat gtgtataaaa atcatctcta actgcagcta
     8881 agggtatagc cgtcaagtcc aaatcccaca gctcatctat cgattttctt acaacaatat
     8941 ctgaatccaa atacagtaca cgagactcgc ttacatactt tggaataaaa tacctaaaaa
     9001 aagccgcata tgaaagtccc tcaaagggga gacgataacc tttcagaata ctactgtcaa
     9061 tctgaacatt cacaatctca ctattcaaag tctctagtct tttttccatc aattggaacc
     9121 attctcgcgg aaggtcatca ttaaaaacat aaaacttaag attataatga tgaacacaaa
     9181 gagattttat tgttgtttca actttatcca tataagcatt atctgcacct aagacaatcg
     9241 cttttttctc ttctttcact ctttatctta tttcttttta ttcccatcat attattccca
     9301 tcatatgttt ctacgtaacc attattttcg cctattcgtt cgtaaaacca taccagtgga
     9361 gattttagat gaagtcccat tacggtttac aatttttaca ttacgacacg gagttttaca
     9421 aatcgatttc atttgccaaa cgtagttagt gaggcagtta gctagttcgc caaatagcga
     9481 ctagcgtcca acaatttgga actttagttc caattgttgg tactgagtca catcttctcc
     9541 tctaactcta cgtctggata cttgtcagca aaccagcgga gggcaaagtc attttcaaag
     9601 agaaagactg gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt
     9661 tcatccaagt cctcaggctt gatccaacga acggtctttt tacccattgg gctcatgacc
     9721 acttccgcat tgtattcgcc ttccatgcgg tgtttaaaga cttcaaactg gagttgacca
     9781 acagctccca gcatgtactc gcctgtttgg taattcttat aaagctgaac ggctccttct
     9841 tgcaccaatt gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa
     9901 actttcatga aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgttttta
     9961 ccaactgtca aggtatcccc aacttgataa gtaccggtat cgtaaacccc gataatatca
    10021 cctgcaacgg cattggtcac attctcacga ctttccgcca taaactgagt aacattagac
    10081 agtttagccc ccttaccagt acgagggaga ttaacactca tgccgcgctc aaattcgcca
    10141 gatacgatac ggacaaaggc aatacggtca cggtgacgag ggtccatgtt ggcttggatt
    10201 ttaaagacaa agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc
    10261 ttgtgaccat gtggttctgg agcaaacttg aggaaggttt caaggaaggt ctgcacacca
    10321 aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc
    10381 tctgaaaact cattcccggc ttcatttaaa agctcaatat catccttgac ttgctcgtag
    10441 aaaggattgc taccaaaaag tttgtcccca tcttctagac tggcaaaacg ctcatcccct
    10501 ttataaagct ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc
    10561 ccgataggcc agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgtaag
    10621 agatccaaag gctcacgacc gtcacggtcc agcttgttca taaaggtaaa gactggaatg
    10681 ccacgatgtt tcacaacctc aaacaatttc ttggtttgag cctcgatccc cttggcagag
    10741 tccacgacca tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag
    10801 tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata
    10861 acagatgaag taacagaaat cccacgttgc ttctcgatat ccatccaatc agatttagca
    10921 aaagtccctg ttttcttccc ttttaccgta ccagcctcac gaatttcacc cccaaagtag
    10981 agtaactgct cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta
    11041 cgacgtttct taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt
    11101 tcttgtttca atagctgaga atgattttta cattggattt taccattcct ttcaacactc
    11161 cattatatcg gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt
    11221 atttatagga aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg
    11281 caagatgaaa attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt
    11341 ctctgaaaaa gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga
    11401 attgctgggc gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa
    11461 gactgtactc cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa
    11521 cgtacctgaa aaagacaact actatatcaa ggtgccagct atcctagacg atggaggaga
    11581 tgcctaatga cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag
    11641 gaaatttctg caacagaatt gacccaaaca acacttgaaa atatcaagtc tcgtgaggaa
    11701 gctctcaatt catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt
    11761 gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa ttccacttgc tgttaaggat
    11821 aacatctcta cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag
    11881 ccaatctttg atgcgacagc tgttgccaat gcaaaaacca agggcatgat tgtcgttgga
    11941 aagaccaaca tggacgaatt tgctatgggt ggttcaggtg aaacttcaca ctacggagca
    12001 actaaaaacg cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca
    12061 gctgtagcct caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc
    12121 caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt
    12181 ttcggtctca ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt
    12241 aaggaaaatg ccctcttgct caacgctatt gccagcgaag atgctaaaga ctctacttct
    12301 gctcctgtcc gcatcgccga ctttacttca aaaatcggcc aagacatcaa gggtatgaaa
    12361 atcgctttgc ctaaggaata cctcggtgaa ggaattaacc cagaggttaa ggaaaccatt
    12421 ctaaatgccg ctaaacactt tgaaaaattg ggtgctattg tcgaagaagt cagccttcct
    12481 cactctaaat acggagttgc cgtatactac atcatcgctt catcagaagc ttcatcaaac
    12541 ttgcaacgct tcgacggtat ccgttacggc tatcgcgcag aagatgcaac caaccttgat
    12601 gaaatctatg taaacagccg aagccaaggt tttggtgaag aagtgaagcg ccgtatcatg
    12661 ctgggtactt tcagtctttc atcaggttac tacgatgcct actataagaa ggctggacag
    12721 gtccgtacac ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg
    12781 ggtccaactg ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc
    12841 atgtacttag ccgacctatt gaccatacct gtaaacttgg caggactgcc tggaatttcg
    12901 attcctgctg gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac
    12961 tctgaggaaa ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa
    13021 caacaacccg tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg
    13081 aagtccacgt agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg
    13141 gaaatgacca aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag
    13201 ttctcaataa aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggaca
    13261 tccacaaaaa gatgcacttt gaccgcaaga actacttcta tcctgataac cccaaagcct
    13321 accaaatttc tcaatttgat gaaccaatcg gatataatgg ctggattgaa gtcaaactag
    13381 aagacggtac gaccaagaaa atcggtatcg aacgtgccca cctagaggaa gacgctggta
    13441 aaaacaccca tggtacagat ggctactctt atgttgacct caaccgccaa ggggttccct
    13501 tgattgagat tgtatctgag gcagatatgc gttcgccaga ggaggcctat gcttatctga
    13561 cagccctcaa ggaagttatc cagtacgctg gcatttctga cgttaagatg gaagaaggtt
    13621 ctatgcgtgt ggatgccaac atctcccttc gcccttatgg tcaagaaaaa ttcggtacca
    13681 agactgaatt gaagaacctc aactccttct caaacgttcg taaaggtctt gaatacgaag
    13741 tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat ccgccaagaa acacgccgtt
    13801 acgatgaagc gaataaagca accattctca tgcgtgtcaa ggaaggggct gcagactacc
    13861 gctacttccc agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa
    13921 tgcggactga gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg
    13981 gtttatcaga ctacgatgct agtcagttga ctgctaataa agtcacttct gatttctttg
    14041 aaaaagctgt tgctctagat ggtgatgcca aacaagtctc taactggctc caaggggaag
    14101 tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa
    14161 acttggttga aatgattgcc atcatcgaag acggtactat ttcatctaag attgccaaga
    14221 aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag
    14281 gtatggttca aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg
    14341 ataacgaagc tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaggccttta
    14401 caggattcct tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac
    14461 ttgcacagga attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt
    14521 ggttttttct tctctaccaa ctcccaataa ctattttggc tttatttcca gagtatttta
    14581 tggtaaaatg aagagtaata atatttatta aagaggtaaa aacatgattg aagcaagtaa
    14641 attaaaagct ggtatgacct ttgaaacagc tgacggcaaa ttgattcgcg ttttggaagc
    14701 tagtcaccac aaaccaggta aaggaaacac gatcatgcgt atgaaattgc gtgatgtccg
    14761 tactggttct acatttgaca caagctaccg tccagaggaa aaatttgaac aagctattat
    14821 cgagactgtc ccagctcaat acttgtacaa aatggatgac acagcatact tcatgaatac
    14881 agaaacttac gaccaatacg aaatccctgt agtcaatgtt gaaaacgaat tgctttacat
    14941 ccttgaaaac tctgatgtga aaatccaatt ctacggaact gaagtgatcg gtgtcaccgt
    15001 tcctactact gttgagttga cagttgctga aactcaacca tctatcaaag gtgctactgt
    15061 tacaggttct ggtaaaccag caacgatgga aactggactt gtcgtaaacg ttccagactt
    15121 catcgaagca ggacaaaaac tcgttatcaa cactgcagaa ggaacttacg tttctcgtgc
    15181 ctaatctcta gaaagaggtc attctatggg aattgaagaa caacttggcg aaatcgttat
    15241 cgccccacgt gtacttgaaa aaatcattgc tatcgctact gcaaaggtag agggtgttca
    15301 ctctttttca aacagatcag tgtctgatac cctttcaaaa ctttcactcg gccgtggcat
    15361 ttatcttaaa aacgtggacg aagaactcac agcagatatc tatctctacc ttgagtacgg
    15421 agtaaaagtt cctaaggtag cggttgctat ccagaaagct gtcaaagatg ccgtccgtaa
    15481 tatggctgat gtagaactcg ctgctatcaa tattcacgtt gcaggtatcg tcccagataa
    15541 aacaccaaaa ccagaattga aagatctatt tgacgaggac ttcctcaatg actagtccac
    15601 tattagaatc tagacgccaa ctccgtaaat gcgcttttca agctctcatg agccttgagt
    15661 tcggtacgga tgtcgaaact gcttgtcgtt tcgcctatac tcatgatcgt gaagatacgg
    15721 atgtacaact tccagccttt ttgatagacc tcgtttctgg tgttcaagct aaaaaggaag
    15781 aactagataa gcaaatcact cagcatttaa aagcaggttg gaccattgaa cgcttaacgc
    15841 tcgtggagag aaacctcctt cgcttgggag tctttgaaat cacttcattt gacactcctc
    15901 agctggttgc tgttaatgaa gctatcgagc ttgcaaagga cttctccgat caaaaatctg
    15961 cccgttttat caatggactg ctcagccagt ttgtaacaga agaacaataa aaagaaaaag
    16021 tgtttgatag atatcaaaca cttttttctt tgcctcccac tatctaaaaa aatgataata
    16081 gatataattg taaacaaaaa tccagatagg ttttgcatga ttgagaaagt taaaaaaact
    16141 atggcagaga atcgttaatc tcagattgtc ggtagaacga taaacaaggg caaaaaagaa
    16201 accaatcaga ctataatata ataaactaat tggatctctg tgagatagta tcaaatggct
    16261 aatcccaaag atgatagcag ataggataac atccaaatag tacttggact agggaaagaa
    16321 ggtattcata aaataccctc tatcaagagt ctcctcaaaa acaggaccga tgattacagg
    16381 caggacaaaa gataagatag tcgataaaaa ggttggttgt ccatttgaaa aaagcacggt
    16441 aaaatactca tcatgaatat tcctatgatt aatcaaatga gcatagcgtg cccaaaaatt
    16501 accgagaatc tgataaacca cataagttgc aaataagtag aagacaaatg accagttcca
    16561 gctctttttc tcaaagataa agagcatctt tttctttttt aacctccaaa ttaatagaag
    16621 gaaacttccc actaatccca ttgttaaaat aagagaatag acatcagctc ctaaccctaa
    16681 aatgatcgtc acatacaatc caattgtttg tggtaaatag gtagatagta aaataataag
    16741 caaaaatatt ccaaattgtc ttagtttttt tgtgtttctc atcgtacttt tttgaaagat
    16801 taccctgctc ggaagccgta cttccaagca tctatataag aattaagtgc cccttgcctc
    16861 atatagggag caaattctct ataatataac catctactat atccatcttc ccaaacagca
    16921 agaccacctg aagtttgctc caagtcctca gttgaaagaa ctgtaaatgt atttgtacct
    16981 gtcattgcaa gtaccttctt aaaatagatt gttgtaggct cacatttata gtatatttct
    17041 ttttttgtct attttatagc ccatctcctc aactggcaat ttttcgacct gaattacatt
    17101 tttccataaa aaatgagacc tttctagtct catttagtca ttcttagtat tttctaaatc
    17161 gttgatagcg ttcttccagc aactcttcta gcggtttttg tgaaagtcta gccagctccg
    17221 tttggagttc ttttttgaca ctcttaatca gttctttact agaaagtcct atttcagaaa
    17281 tcaccttatc caccacgtcc atttctaaca gttcatgcga agtgattttc atcagttctg
    17341 ctgcttccat agcgcgagta ccgtccttcc ataaaatgga agcaaagcct tctggactga
    17401 gaatggcata gatagaattt tccagcatcc agacacggtc cgcgacagct agagccagag
    17461 ccccgcctga accaccttca ccgataataa tggcgataat aggaactttc aggtcactca
    17521 tttccatgag attgcgagcg atagcttccc cttgaccacg ttcttccgct ccgacaccag
    17581 gataagcacc tgctgtattg ataaaggtca caactggacg gccaaatttc tcagcctgtt
    17641 tcatcaaccg cagtgccttt cggtagcctt ctggatgtgg ttggccaaaa ttccgtttga
    17701 ggttgtcttg caaactcttg cctttttgga taccaaccac tgttacagct tggtctccaa
    17761 gccaaccaat accaccaaca actgcaccat catcacgaaa agaacggtca ccatgtaatt
    17821 ggataaattc atcaaaaatg cctgtcgcaa agtccaaggt tgtcaagcga ctctgctcac
    17881 gcgcttctct gactattttt gcaatattca tctaggactc cctccatgca atctgactag
    17941 gctagcaatc gtatctggta agtctcttct tttgacaata gcatccacaa agccatgttc
    18001 taataggaat tctgcctttt ggaaatcctc aggcaagctt tcacgaaccg tattttcaat
    18061 cacacgacgc ccagcaaaac caaccaagct ctgtggttca gccagaatga tatcgccttc
    18121 catagcgaaa gaagctgtca caccaccagt cgttggatct gtcaaaatgg tcaggtaaaa
    18181 gagaccagca tttgaatgac gtttaaccgc cgcagagatc ttagccatct gcatgagact
    18241 catgattcct tcctgcatac gggctccacc agaggctgtg aataggacaa ctggcaattt
    18301 ttcgacagtc gcatactcaa acaaacgagt gattttttca cctacaaccg tacccataga
    18361 agccatgata aagttagaat ccataatccc aagagccaca gtctgacctt taataagagc
    18421 agttcctgtc acaacggctt catgcagacc tgttttttca cgcatagatg ccagtttctt
    18481 ttggtaacca gggaaatgca agggatcctt gctttcaatc cctgtaaaca attctttgaa
    18541 ggttcccata tcaatcgtca aagccaagcg ttcttgggca gaaatacgaa aggtatagct
    18601 acagtgcgga cagatacgtt cacttcccag atccttctga tagatggtat gcttacagcc
    18661 tggacactgg gaaaataatt catctggaac ctctggctta gcttgaggtt tttccctaac
    18721 tgaacgattg ggattgattc gaatatactt atctttttta ctaaatagag ccattgattc
    18781 cccttttcgg tttaaactct taaagtcatt ttattctttt tcttgatatt taggtaagaa
    18841 ggtttccatc aagaaggaag tatcataatc cccagcaatg acattgcgat ctgaaatgag
    18901 gtcaagctgg aaatctgcat tggtctgcac tccttcaatc tctaattcat agagggcacg
    18961 ttgcattttc atcaaggcgt caaaacgatt ttcgccgtgt actatgattt tggcaatcat
    19021 actatcataa taaggcggaa tggtataacc tggataaact gctgaatcca cgcgcaagcc
    19081 aactccacca cttggcagat agagattagt aatcttacct ggacttggag caaagttaaa
    19141 ggctgggttt tctgcattga tacgacactc gatggcatga ccgcgtagga caatatcttc
    19201 ttgcttaaca gacaaaggct gacctgccgc aatgcaaatc tgttccttaa cgatatcaac
    19261 acctgaaaca aactctgtta ctggatgttc tacctgaaca cgagtattca tctccatgaa
    19321 atagaaattg ctacttgctt catcaagaag aaattcaatg gttcctgcat tctcatagcc
    19381 aacaaactct gccgctcgaa cagcagcagc acctatttca tgacgcagcg tttttccgat
    19441 tgcaatcgag ggactttctt ccaaaacctt ttggttattc ctttgaagag aacaatcccg
    19501 ttcacccaag tgaatcacat gtccatgctc atcacctagg atttgaacct caatgtgccg
    19561 agctggatag ataacccgtt ctatgtacat ggcaccattg ccataattgg ccttggcctc
    19621 actagaggca gtttcaaagg cagaaacgag gtcatctggt ttttcaacct tacgaatccc
    19681 tttaccacct ccacctgctg aagccttgag cataacagga tagccaattt tttcagcaac
    19741 aatcaaagct tcttcagagt tatgcacttc tccatctgaa cctggtataa caggcacacc
    19801 tgctttaatc atctgagcac gcgcattgat cttatccccc atcatatcca taacatgacc
    19861 agatggaccg ataaacttga tacctacttc ttcacacatg gtcgcaaatt tggaattttc
    19921 actgagaaat ccaaaaccag ggtgaatagc ttctgcctca gtcaagactg cagctgatag
    19981 aactgcatta atattgagat aagactctgt tgccttgcca ggaccaatac aaactgcttc
    20041 atctgccaaa agcgtatgaa gagcttcctt atcagcagtt gaataaaccg ctaccgtcgc
    20101 aatccccaat tcacgtgccg cacggataat acgaaccgca atttcaccac gattggcaat
    20161 taaaattttt cgaaacatgg agaacctcct tagttcccaa ttgcaaaagt aagggtacca
    20221 ctggctgcaa gcttgccatc cacttcagcc tttgcttcaa ccacagctat ggtgccacga
    20281 cgttttacaa aagtcgctgt cataaccaat tggtcgcctg gtacaacttg cttcttgaac
    20341 ttaaccttgt ccataccagc gtaaaagacc agttttcctt tattttcagg ttttgataac
    20401 tccaacacac cggcagtttg cgccaaggct tccataatca gaacacctgg cataactggg
    20461 tattgaggaa agtggccgtt aaagaaaggc tcgttgatgg tcacattttt gatagcaaca
    20521 atggtatcct cgctcacttc caagacacgg tccactagaa gcataggata acggtgggga
    20581 agagcttctt tgattccttg aatatcgatc atttgatacg taccaatcct ttaccaaact
    20641 caaccatttc ttcgttagag acgagaattt ccgttaccac accatcctta ggagctggga
    20701 tttcattcat gactttcatg gcttcgataa ttaccaatgt ttgacctttt ttgacactat
    20761 caccaactgt aacgaaggca ggtttatctg gtccagcagc caagtaaacc actccaacaa
    20821 gtggactctc tacaagattt ccctcagtag ccacacttgc ttcagctgga gctggaactt
    20881 cttctgctac agtctctgct ggagcagatg taggagctac tggactcggt gttgctagaa
    20941 cgggtgctgg agcgacttga gttgcaactt caggcacagg tctcgcttca ttcttgctaa
    21001 actgcaactc atccgtccca tttttataag aaaattctct caaacttgac tggtcaaatt
    21061 gagtcatcaa gtctttaata tcgtttaaat tcatacttat ctattctccc aacgtttgaa
    21121 agcaagaact gcattgtggc ctccaaaacc aaaagtattt gaaatagcgt atggaatttc
    21181 tttctccaag ccttgtccat aaacgacatt agcttcgata taatctgata cttcacttgt
    21241 cccagctgtc attggtacaa agttatgacg catagcttcg atggtgacga tagcttctac
    21301 tgcacccgca gcccccagca aatgtcctgt aaaagacttg gttgatgata caggtacttc
    21361 cttaccaaga acagctacga tagcaccact ttctcctttt tcattggcag gagttgacgt
    21421 tccgtgagca ttgacatagg ctacttgctc tggagaaatc tcagcttctt ccaaggctag
    21481 tttgatggcc ttgatagctc cctgaccttc tggatgtgga gaagtcatgt ggtaggcatc
    21541 acaagtattt ccgtaaccaa ccacttcagc caggatagta gctccacgtt tttcagcgtg
    21601 ttcaagactt tctagaacca acatccctga accttcaccc ataacaaacc cattgcgatc
    21661 cttatcaaat gggatcgaag cacgagttgg atcctctgta gtagagagag ctgttaaggc
    21721 ttggaaacca gcgatggcaa aaggtgtgat agaagcttct gttcctccca ccaacatcac
    21781 atcttggaaa ccaaacttaa tagagcggaa ggcatcccca atcgcatcat ttgatgaaga
    21841 gcaggcagta ttgatagatt tacaaacacc atttgcacca aaacgcatgg ctacattccc
    21901 agaagccata tttggtaaag cttttggaag agtcattggt ttgacacgtt tgggtccttt
    21961 ttcatgaagg cgaagtacct gatcttcaat ttccttgatt ccaccaatac cagatgcaac
    22021 gataacacca aaacgatccc tattaagagc ctctacatca agattggcat gatttacagc
    22081 ctcttgggct gcatacaagg catataaaga atagttatca aaacggttgg tatctttttt
    22141 tacaaagtat ttatcgaacg gaaaatcttg gatttctgcc gcattatgca catcaaagtc
    22201 actatgatca aattttgtaa tgccaccaat gccgattttc ccagttgcta aactattcca
    22261 aaattcttct ggtgtatttc cgattggaga tgttactcca taacctgtta ccactactcg
    22321 atttagtttc attcttttca cctctagctt tcgctacata cttaagccac catcaatggc
    22381 aaccacttga ccagttagat aatcttggcc tgctaaaaat actgtcaaat ctgcaacctg
    22441 ctctgcctgc ccaaattctt tcatcggaat ctgagctagt gtagcttcct taatcttatc
    22501 tgataagata gctgtcatat cagactcaat cattcctgga gcaatcacat tgactcgtat
    22561 attccgacta gcgacctcgc gtgccacaga cttggtaaag ccaatcaagc cagccttaga
    22621 agcagcatag ttagcttgac caatattccc catcaaacca acaacactag acatattaat
    22681 gatagcacct tctctggctt tcatcatcgg tttcaagact gattgtgtca tattaaaggc
    22741 accagtcaga ttgaccttga gcactttttc aaaatctgct tctgtcatct tgagcataag
    22801 agtatcttgg gtaatccctg cattgttgac caaaacatct actgaaccca gttctgcaat
    22861 agcttgatca atcatacgct tagcgtctgc aaaatctgat acatctcctg aaatgggaac
    22921 caccttgata ccatagtttg aaaactcagc gagcaattct tctgagattg ccccacgact
    22981 gtttaagaca atgttggctc ctgcttgagc aaacttgtgg gcgatggcaa gaccaattcc
    23041 acgactcgaa cctgtaataa agatattttt atgttctagt ttcatttttt tcctttcaaa
    23101 acttctactt attttagtct atttttctaa aagtgctact aaactcgctt gatcttccac
    23161 atgagctaag tgagcagttt gatcaatttt tttaacaaaa cctgacaaga ctttccccgg
    23221 tccaatctcg ataaagttgc ttatgcctgc ttcttgcatg accccaatac tttcatagaa
    23281 acgaacgggt tccttgacct gacgcgtcaa gagctgagca atgtcctctt tttgcatcac
    23341 agcagcttct gtattgccga ctaggggaca agtaaaatct gaaaaactta cctgagctag
    23401 agtttcagct agtttctggc tagcaggctc aaggagagcg gtgtgaaagg gacctgacac
    23461 cttaagagga atcaagcgtt tggcacctgc ttcttgcaaa agttcaaccg ctcgatcaac
    23521 tgcaaccact tctccagcaa tgacgatttg tgcaggtgtg ttatagttgg ctggagtaac
    23581 cactccaagt tcagaagctt tttgacaggc ttcttcaatg acctctactg gcgtattgag
    23641 aactgctacc atcttgccag agtcagcagg agccgcttct tccatatagg ctccacgctt
    23701 agctaccaag gcaaccgcat cttcaaaatc caaggcgccg cttgccacca aggcagagta
    23761 ttctccaaga gacaaaccag caaccatatc aggctgatag cccttttctt gcaataaacg
    23821 gtagatagca accgaagtcg ctagaatggc tggttgcgta tagcgggtct gattgagttt
    23881 gtcttcttcc gtatcgatga gataacgtaa atcataaccg agcacctgac tcgctcgatc
    23941 aatcgtttct ttgacaatcg gatactgatc atagaaatcc cgtcccatcc ctagatactg
    24001 ggcaccttga ccagcaaata aaaaggctgt tttagtcatt tcttacaact cctgcccagc
    24061 gagaggcttc ttcttgaatt ttcttagcgg ctccgtaata caaatctttt aggatttctt
    24121 cagctgtttc ttctttagaa acaagccctg cgatttgacc tgccatgaca gagccaccat
    24181 ccacatcacc gtgaacaact gctttggcta gggcacctgc tcccatttgt tcaaagattt
    24241 ctaaatcagg atcttcctgc ttaaaggcat ctttttcagc cagttcaaaa tctctagtca
    24301 actgattttt aatagcacga acagcatgac caaagtgctg agctgaaatc gtagtatcaa
    24361 tatcccttgc ttttaaaatt ttctccttgt agtttggatg ggcattcgac tcttttgcaa
    24421 ctacaaaccg tgtccccacc tgtacagcct ctgcacctag cataaagcca gccgcagcac
    24481 cttcaccatc cgcaattcct cctgcagcaa taacaggaat agatatagct gtggctacct
    24541 gtcgcaccaa ggtcatggtt gttaatttac cgatatgccc cccagcttcc attccttctg
    24601 caataacagc gtctgcaccg attttttcca tgcgtttagc taaagcgaca ctaggaacaa
    24661 caggaataac gattatccca gcttcatgga aacgttccat atacttgctt ggatttcctg
    24721 ctcctgttgt gacaacttta acaccttctt caataacgag atccacgata tcttccacaa
    24781 agggagataa gagcatgatg ttgaccccaa agggtttatc agtcaatgat ttgattttat
    24841 caatattggc cttgacaact tctttcgggg catttccccc accgataatt cctaatcctc
    24901 cagccttgga aacagcccct gccaaatcac catcagcaac ccaggccatc cctccttgga
    24961 aaataggata gtcaatcttc aataattctg taatacgcgt tttcatagtg cctccaacct
    25021 tccttgctta cgtaatagtt cgatttcacc ataatttgac agtcaaacta ttacctaaac
    25081 aagagggagt gggtttctcc ctactccttc tactaatatt ctgcttattt tgcttgctct
    25141 tcaacgtaag caaccaagtc accaactgtt ttcaagtcat tttctgcttc gatttggata
    25201 tcaaaagcat cttcgatttc tgagattact tggaacaagt ccaatgaatc tgcgtccaaa
    25261 tcatcaaaag ttgattcaag tgttacttct gatgcgtctt ttccaagttc ttcaacgata
    25321 atttcttgta ctttttcaaa tactgccatg ataggactcc tttaaaataa atagtttttt
    25381 tataacaatg tgttcaccac atgattacct aaattgtaag aatgagcgtg ccccaggtca
    25441 agcctccacc gaagcctgat agaagaacag tctggctacc atctaaaggg atgagacctt
    25501 gttctacaca ctctgaaagt aaaatcggga tactggctgc actggtattg ccatattcca
    25561 tcatattggc tggaagtttg gctcggtcaa caccaatttt tctagccatc ttatccaaaa
    25621 tacggtcatt ggcttgatga agtagcagat aatccaagtc tgtcacctct ataggagatt
    25681 catcaatagt ctgcttgata gacttggcta catctcgaat ggcaaaatca aagactgtgc
    25741 gtccatccat cttcaaaaac gaatctgcac tttcttgatc tgaaaatgga gaatgcaaac
    25801 ctgaatgccc ataagttaaa cactcgctgc gacttccatc gctattgaga ctctcagcta
    25861 agaaatgctc ttgctcgcta gcttctaaca agacaccacc agcaccatct ccaaacaaca
    25921 cagctgttga tcgatccgac caatcgactg ccttagagag ggtttcacta ccaatcacca
    25981 agcctttttg aaagcgacca gaagcgataa acttttcagc agttgaaaga gcaaatacaa
    26041 atccactgca agccgcggtt aagtcaaaag caaaggcttt attagcgcca atattagctt
    26101 gaacacgagc agctgtagag ggcatcatcg aatctggagt aatggtagct aggatgataa
    26161 aatccagttc ttttcctgtt attccagctt ttgccatcag tttcttagca acctctgtag
    26221 ccaaatcact ggtagattct gttcttgaaa tatgcctttg tcgtattccc gttcgacttg
    26281 aaatccactc atcattggta tccataatct gagccaagtc gtgatttgta accacttgct
    26341 ctggcacata atgagcaacc tgacttattt ttgcaaaagc cattatttca aatcctccaa
    26401 aaattggtaa agattagtca aacctttacc catgacagca atttcttcct cgctcatgcc
    26461 atcaataatt ttttctacca tggccttgtg gaagcgttta tgcagcctat gaatcaagcg
    26521 acccttcttt gtcaaatgca gatgcaccac acgacgatcc tgttctgacc gaactcgctc
    26581 aatgtagccc ttacgctcta aattgttcaa acttgtcgta acagttccaa gagttaccat
    26641 caactctttt gacacttgac ttggagtcac gtctggagcc ttaccgatga catcaatcgt
    26701 atgcatttct ttgatggaga tatccttaaa acgactacct ctcaagttca cttcctcaat
    26761 tacaaggaca ttgttaaata tagatgttaa atattcattg attcgttggt agtccatttt
    26821 tcatatccct ccttcttcaa aaaactttta caatcaaaac atttgacaga aagaattata
    26881 tcaaaattca aagaatgatg caagtatttt ttattttcct gtaaatttag gtcttcttct
    26941 ctccgaatga gctcgcactc cttctttgaa atcctctgtt tgagctaagg atttctgtag
    27001 gttcagttct aaagtagcgt aaccctgcca gtctttaaat tggctctccc aaaccaactt
    27061 cttaatggca gcataggaat tacttgaagc acgtcttaat tttttaagaa gctgttctct
    27121 cgtcttttca agtttttcag cttcagaaac gcgataaacc aacccccatt ctagggcttt
    27181 ttctgccgtt aaagcctctc ctgtcatagc taattgagca gcacgcgtca caccgatact
    27241 gcggctcaag agatgaattc cccctgcatc tggagccaaa ccaacaccaa caaaggcttg
    27301 gataaactta gccttatccg tcgccaaaca gaaatctgcc gcaacagcca tattcgctgc
    27361 ggcacctgca acagcaccgt caacttccat taaaacaggt ttggctattt gcttgatttt
    27421 ataagaaatc gtattgacca actctgcgat ttttgtcaat gatggaatat catcctcatc
    27481 cactgcccgc ttcatctcta ccaaatctcc cccaactgag aagacctttc cattggcatt
    27541 gattaagata aaatgcacag ctggattttc ttctgccaaa gtcagagctt ctaaaatctc
    27601 ctcacacatg ggaatatgaa aaccatttgc gacctcagga cggttcaagg taaggattgc
    27661 caagtcctct tcaagctgat aaataatgtg ttccatcagg gctccttttt attttataag
    27721 cagtttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctgc aacctcaaag
    27781 cagtgctttg agctgacttc ggctagcttc ctagtttgct ctttgatttt cattgagtgt
    27841 taaattattt cactgtcaaa gtatatcttt tttaggagca gaaagcaaga aaaaatcgac
    27901 tgaaagtgtc tcagccgata agaaaggctc gctttaggct agaaagcatc ttattttctt
    27961 cattgaaaaa agcctttctt tctgctataa tcgtataaaa tacttacttt aggagttctt
    28021 atgaaagttg ttaaatttgg aggtagttct cttgcctctg ctagtcaatt agaaaaagtt
    28081 ttaaacatcg tcaaaagcga ttcagagcgt cgttttgtag tcgtttctgc gcctggtaaa
    28141 cgcaatgctg aagatactaa ggttacggat gccctgatta aatactaccg cgactatgtt
    28201 gcgggtaacg atattagcaa gagccaaagc tggattatcg accgctatgc tgctatggtt
    28261 agtgaattgg gactaaaacc agctgtgcta gaaaaaattt ctaaaagcat tcacgccttg
    28321 gccactcttc ctattgaaga caatgaattt ctctacgata ctttcctagc agccggtgaa
    28381 aataacaatg ccaaattgat tgctgcctac tttaaccaaa atggtatcga tgcacgctat
    28441 atgcacccta gagaagctgg gattgtggtc acaagtgaac ctggtcacgc tcgcatcatt
    28501 ccatcaagtt atgacaagat tgaagaattg acaaacacca atgaagtcct tgtcattcct
    28561 ggtttctttg gtgtcactaa ggaaaatcaa atctgtactt tctcacgtgg aggttctgat
    28621 attacaggtt ctatcattgc tgctggtgtc aaagccgacc tctatgaaaa ctttacggac
    28681 gttgatggta tctttgcagc ccaccctggt attatccacc aaccacactc gattcctgag
    28741 ttgacctacc gtgaaatgcg cgagttggcc tatgcaggct tctcagtcct tcatgacgag
    28801 gctcttcttc ctgcctaccg tggaaaaatt cctctggtta tcaagaatac caacaaccct
    28861 gaccatccag gtactcgtat cgttctaaaa cacagtaatg atgaatttcc agttgtggga
    28921 attgctggtg actcaggctt tgtcagcatt aatatgtcga aatacctcat gaaccgtgag
    28981 attggatttg gccgcaaggt tctgcaaatc ctggaagaac ttaacatcgg ttgggaacat
    29041 atgccaacag gtatcgacga tctttctatc attctccgtt ctcgccaact aactcccatc
    29101 aaggaagaag aaatcctgcg tcagttggtt caaaaggcta aagtagatca tgcagaaatc
    29161 gaacacgacc tttctatcat tatgattgtt ggtgaaaaaa tgaagagcca catcggagtg
    29221 actgctactg cgacacgcgc tctatctgaa aacaaaatca acatccagat gatgtctcaa
    29281 ggttctagtg aagtttctat tatgtttgtt gtcaataaag accaagagaa agcagcaatt
    29341 aaagccctct acaatgcctt ttttggagaa agtaaggaag actaagcatg gcccaatcac
    29401 ttaacaaaac agtactcctc agtacgacag gcacttccta cctctctatc gctgggaaag
    29461 ttgggaaatt ccttgtcgga gatcaggctt tggaatttta cccagatgtc aatgtcgaac
    29521 aatttatcca gattccttgg agccatatca atcagattgg agccaatgtc actggacgca
    29581 aaatcagccg ccacttcgaa gtctttacag acaaaggaaa attcctcttt gcttcaaaag
    29641 actcaggtgc cattctcaaa attgcacgcg aaaaactagg caatgacaag gtcgtcaaac
    29701 ttccgaccct gattcagaca attagccaaa aatttaaaaa tctatttgca aaaaagtaga
    29761 aactttagta taatcatagc aacggataag taggttatct tcttctttca gaaagtctgc
    29821 gggtactgcg agcagatagg agggataggt gaaattctac cgttagtaac aattacatac
    29881 acaatcaagt gcacacctgt gaagttggat ggaaccgtgg ccctgccact ccaacgtttt
    29941 gtcaggcgtg cttttttcat aaaggagttc ttatgttaga tatcaaacgt attcgtacag
    30001 attttgaagc tgtcgcagaa aaattagcta cacgtggtgt agatgctgct gtcttgaatg
    30061 aaatgaaaga aatcgatgct aaacgtcgta acatcttggt caaggttgaa actctcaaag
    30121 cagaacgtaa cacagtttct gctgagattg cccaagctaa gcgcaacaag gaaaatacag
    30181 atgacaagat tgctgccatg caaaatctat ctgctgaggt taaagccttg gatgctgaat
    30241 tggcagaaat cgatgctaaa ttgacagaat ttacaacgac tcttccaaat atcccagctg
    30301 acagcgttcc tgttggggct gacgaagacg acaatgtgga agttcgccgt tggggtactc
    30361 cacgcgagtt tgacttcgaa cctaaagctc actgggatct cggtgaagac cttggtattc
    30421 ttgactggga acgcggtggt aaggtaacag gcgctcgctt cctcttctat aaaggcctcg
    30481 gtgctcgttt ggaacgtgct atctacaact ttatgttgga tgaacatgga aaagaaggct
    30541 atactgaagt catcacacct tacatagtca accatgattc tatgtttggt actggtcagt
    30601 atccaaaatt taaggaagat acttttgaac tcagcgatac caactttgtc ttgattccaa
    30661 ctgctgaagt tcctctgaca aactactacc gtgatgaaat cttagacggc aaagatcttc
    30721 caatctactt cactgccatg agtccgtcat tccgttctga ggctggttct gccggtcgtg
    30781 atacgcgtgg cttgatccgt ttgcaccaat tccacaaggt tgaaatggtc aaatttgcca
    30841 aaccagaaga atcttacgaa gaattggaaa aaatgacagc caacgctgaa aacattcttc
    30901 aaaaactcaa ccttccatac cgtgtcgttg ctctctctac tggagatatg ggcttctcag
    30961 ctgcgaagac ttacgacttg gaagtatgga ttccagcaca aaacaattac cgtgaaatct
    31021 caagctgttc aaacacagaa gatttccaag cccgtcgtgc ccaaatccgt taccgtgatg
    31081 aagcagatgg caaggtgaaa ctccttcata ccttgaacgg ttctggactt gcagttggac
    31141 gtacagtggc tgcaattctt gaaaattacc aaaatgaaga tggttctgtg accatcccag
    31201 aagcacttcg tccatacatg ggtggagctg aagtcatcaa accataaaaa ataaggttta
    31261 gctatttcta gctagacctt ttttcgtaac caaatcagat aagcacctag tacaaagaat
    31321 aaaatagtta ggcatataat ggtttcagcc aataccaggt aatccagaaa tggaagtttc
    31381 aaaattccct gagccatctt gagcgaggtc gctgtgataa tggttgggaa ggtgagggct
    31441 gagaaggctg gttgaaaacc ttgttttaaa atgttgggca gacgagttaa aacaaagaaa
    31501 aagaaggatt gagaagccaa aatcatgaca atcaagaccc aagtcggcag gctggttcct
    31561 cctactcgaa ctagagaagc caagagtaga gagaaaggag cacagtagat tccttcttgt
    31621 ccaagcaagg ctagtgggag tggatgtttc tttaaatcgc tataaataag gggatagaga
    31681 tagaaggtca agagaaaacc aaaactcaag gtcgcatagg ccatttcgat aatacctacc
    31741 agaggatagg tcaaggcagc cactgctatc cccacataga gaaccgtcca acttggagtg
    31801 gcatgaaccc tccgccctgg acaagcaaac ttgatggtaa aaccagcaat caaggtcaaa
    31861 tccaagagaa atgaaaacca ccaaatccct tgtgctacca aaggaagata agagaatacg
    31921 cgaaagacat aggtcgataa aatcatccca gccataggaa aggttgccat tcctgacaaa
    31981 agagggggct tggtcaattc ttgcttggtt tctttccaat taaagagatg cagaattaga
    32041 aagtaaatcc ataaaaccaa accagtcaga ctaaaaagat gggatagaac tggcaacgta
    32101 tctaaaataa gatttccagc tcctgccaaa cctagcaaac aacctgaaaa tactaagggg
    32161 agttttttca tcctaacctc caataatcat gttagtttca gtataacata aaagcgctta
    32221 aatgaggatt taaaaaaacg aagtccgatt atttcagact tcattttact cagatatgaa
    32281 ttaggcataa ggttgcaatt ctggattaat tggtgtatta gctaagttgt tggcatagtt
    32341 acagaggatt gctaggctga caccaaaaac cacatccaag gcattttgtt gagtgtagcc
    32401 agcttctaaa aactcagaca aggcttcatc tcctacacga cccttggtat tgataactgc
    32461 caaggtaaac ttagctaggg tatccaattt aggatctgtt tcaattggag tacgattgcg
    32521 aagagcttga atcaagtcat cattcatctg gatttgtttg atggaaaagg ctgtgtgacc
    32581 tgcgacacag aaggcacaac cattggtcac ggctgccgtg atttgcacca cttcacgctc
    32641 aacgggtgtc aggctgttgc gacggtggat agatgagaca atttggtagg cttctaaaac
    32701 agtcggggca ttggccaaga gaccgattag gttgggaata tagccattgt tgtctttttc
    32761 tactgtttca agaatttctt tcacttctgc tggtgctgac tctactgtat ggatagtaaa
    32821 tgttgtcata agatacctct tttcttatta ttgacactaa tattattgga aaatcttata
    32881 aaatcctgat tcctaagttt atctaagata aagctttatt ctctcataag attttcgttg
    32941 ttatattagt ttatcacact tccaatcact tgcataatat atattatata tcaggctgat
    33001 aaaaattatt tataggcaaa aaaatcacac gagctgtgtg attccattat ttgtcaaaat
    33061 actttttagt ttcagcaata acgactggcg acaagaccaa gagggcaatc aagtttggca
    33121 gagccatcaa ggcgttaacg atatctgcga taatccagac catatccaac tcgataaatc
    33181 ctcctaacaa gaccatgagc acaaaaacca cacggtagag ccagataaag cgaaccccaa
    33241 agaggaactc aaaacagcgt tctccgtaat agttccaacc tagaatcgtt gtaaaggcaa
    33301 aaagtacaag gaagatggtc aagagagcag gcccaaagtg tgaaaagact gttgagaaag
    33361 ctgactgagt caaggcaacc ccattcaagt caccgctcca aactccagtt accaagatgg
    33421 tcaaaccagt tagagtacaa atgatgaggg tatcaataaa ggttcctgtc atggaaatca
    33481 aaccttgctc tactggttca tttgtcttgg cagctgcagc tgcaatagga gcagaaccca
    33541 gaccagattc gtttgagaac acaccacgcg ccacaccatt ttgaatagcc atccgaacgc
    33601 tagcaccagc aaatccacct accgcagcaa ggggactaaa agctgaggta aagactaaag
    33661 cgattgtgcc agggattttt ccgatattaa agaaaataac tgtaagagtt cctaagatat
    33721 aaatgagggc cataaaagga acaacagtag ttgaaacctt agaaatagac ttgagtccac
    33781 caaagactgc aatcgctaca aagacagaca agacgagaga tgtgatggct ggcgaaatcg
    33841 tcgttgtatt ttggatagat tctgtaatcg agttgacttg ggtgaaggtt ccgattccca
    33901 agagagcaac caatactcct gctactgcaa acaaaacagc aagtggtcgc cacttttctc
    33961 ccatccctag aaggatatag tgcatgggac ctcccgctac tgcaccatgg tcgtccttgg
    34021 tgcggtattt gatggccaag agtccttccg catacttggt agccattcca aagaaagccg
    34081 ccatccacat ccaaaataga gctcctggtc caccaacctt gatagccgtc gcaactccta
    34141 tgatatttcc tgttccaaca gttgatgcca aggctgtaca cagagctgca aaactggata
    34201 catcaccatg tcccttatcc tggataaaaa taagctgaaa ggccttgggt agacgcaaaa
    34261 cctgcaagag tcctagccgc atggttaggt aaatccctgt tccgaccaat aaaatcaaga
    34321 ggggcggtcc ccaagcaaaa gcatcgattg atttaagcaa ttctaacatt tccttctcct
    34381 atcgtttcaa ccccaaaaga aagagcacat gcaagataca tgtactctgg aatgcttaga
    34441 taaatgctaa aaagcggtct atcctagctc tgtcctttta cctgagagtt tgagcagttg
    34501 cctgccttgc cccttcggtg cctttacggt ctctccagag ttccgtccat ttacagtcat
    34561 ggaaaatcaa acgattcccc acttctatta aacttcattc ggtgttggta tttaattgat
    34621 tctaatttta caaaaaatgt tggcttttgt caatgtgttt attagtaaaa attagttcaa
    34681 cagtttttac tttataaagt ccagaatact gctatccttt aaaagtgaca atagtcgcac
    34741 cactgcctcc agcattttgt ggggcatagc cgaaactctt gacatgtttg tttctttgca
    34801 agtatttggt aactccttca cggatgactc ctgttccgat accatggatg atatcaactt
    34861 gagccatatt gttaagcaag gcttggtcga tgaaggtatc tagctcattc atggcttctt
    34921 catagcgctt gcctcgaaga tccagtctag cttgaggtcc tcgcccagaa gttcgtttca
    34981 caacattgac ctgtttcttc ttgactggtt tttcttgctg ggcttgaaca agatcaaact
    35041 ctttctcttc caaggtcatc ttaatcaagc caacttgggc ttcccagcgg ccgtccttga
    35101 gttgactggt caaggtacca cgctgaccat aactgagaac cacgatatca tctcccacct
    35161 ttggagctcg ttttttcttg gccttttgaa ggaccttgtt tttagacaag tccacttttt
    35221 caggagccaa ttttttcaac ttggccttgg cttcaatgat ttcgtggggc ttgagttggg
    35281 atttactgtg gagatttttg agaatctggt cactttcact tagggccata tccacaatct
    35341 cagcagcctg ttcacgcgcc ttgttaagct cggtttcctt ttcacgatta agctcgttgt
    35401 agagtttttt tagagcacgg ttcatcttga gattttcttg ctccacctca cggatattgt
    35461 ccaagcgttt gcggctttcc agcgtctgct cttctaattg ctcaatgata cgattgacgt
    35521 cattgtcctg atcaatctgc tgactggcat ctcctacgat aacttcagat aggcctagac
    35581 gtttggcaat ttcaaaggca ttacttcggc caggaacacc ctgcataaag cgataggtcg
    35641 ggcgaagagt tgcagtatca aactccatac tggcattttg cacaaaggct gtctcaatac
    35701 cgtaggcctt gagttctgga tagtgggtcg tcgccatggt cttgatttga cgcaggcgaa
    35761 ggtcctccag aatagccatg gcaagggctg ctccctcttg gggatcagta ccagccccca
    35821 actcatccaa aagtaagagt gaatgttggt tgaccttgcc aagaatatcc acgatattgg
    35881 tcatatggct agagaaggta gacaagctct gctcaataga ctgctcatct ccaatatcag
    35941 caaagatttc ttcaaaaata ccaacacgac ttcccttgtc tgctaaaatc ggcaatcctg
    36001 actgggccat gacctgtgtc aagcccagag ttttgagcat gatggtcttc ccacctgtat
    36061 tgggacctgt aatgacaata gctgttaaat cttgaccaaa atagacatca tttgcgacgg
    36121 catttttgac caaaggatgg cagacatgga gcagttgaat ctcttgattt tctgacagct
    36181 gaggcacgac tgcttgtctt tcttggataa atcgaacctt ggcacgaatc aagtccagat
    36241 gaccgataat ccaagcgtca ttagcaatct cagccgcatg agggcggaca cgctcagaaa
    36301 tttcttggag aatgcgaagc atttcatagc gctcatctgc tcgcagacta gcaatttctt
    36361 cgctcagttt gactacctca cgtggttcga tatagacggt gtttccacta gcagaaatat
    36421 catgaacgac acctgcaatc ttattgcggt aggtgttttt gactggtaaa acctgacggc
    36481 catttctgct agcaacaatt ccttctgtca acatctgcgc tttttgcttg agcaagtctt
    36541 gtaaaacatc gcgtacctga ctctcgctat catgtatttt tcgacggatt cgcgccaatt
    36601 cttcactggc aaaattttca atgaaacccg catcattaaa ggcctgaaga tttccttgta
    36661 attgcggaaa atcatgtaat ttctcaaacc aaagggctaa ttcttccaag ctgacatttt
    36721 ccagattggc gtaaaaactt tgaagttctc ggctggcaag aagcacgcgt ttcaagagta
    36781 ggaactcctc gatattgaga tccgctccca tctccaacct cttgcagact cctgcaattt
    36841 ccttagttga gagaatagta aaatgcggtt gctcgacgaa aagagcctgc atttccttca
    36901 tctcagcaaa agcctgtttg attttatctg ctttggcagt cggagccagt tgtctcaatt
    36961 gctccaagcc ctgctcggtc aacaaatgag gctcaaacaa ggccttgacc ttatcgaact
    37021 ctaatgtttc taatattttc ttattcatct ttatttcctt gtctttgaat gtctaggtgt
    37081 ggtagctttt tacattctga tagattcgag tcaaatctgt aaacaaaggg ctaggaaaac
    37141 tcctgccctt tttatccgat taaatttgtc acccagattt gtttgagcca actggttgtt
    37201 atcggtatgc tctggatgat gtgttttgcg acgatactct tttcaagagg attttgtata
    37261 actgccatgg ggatggtcgc caagattgtc aaggccattt gcaagacaaa taaggtcacc
    37321 aacatggaca agatacctgc tgaaacttgg aacaacttac cacccagttt tttgctagga
    37381 atcaagtgta agagaagacc aagcaaacga ccaatgctat agacaatccc aaatacaagc
    37441 aagtagccga tgcctgcata aaagacctta tccagctgaa agagttgatc cgatgggaaa
    37501 aagaaagtcc cctgaccttc ctgcgaattt gcataaggga gcaataaatg gaattgctct
    37561 ccaagcccct tataaaactg gccagccata aaagccgatg ccatggctga aatcaggtaa
    37621 taaacctgta agagcaggcc tctccgatag ccgatataaa atccccaaac caagaccaat
    37681 agaagaagga atgaaatcat aaggaatcct caatcttgct ctgttcttgc ttacaagtca
    37741 caagcttgtg acggagttct tctagctctt gctccttatc gtcaaattca atctcacggc
    37801 tgagctgagt tgataaacag ttgactgcca acaaaagagc gattgtttca tcatctgcgc
    37861 taggcatttg ttctttaatt gcttggtatt tttctgtcgc aaccttagcg atttcctcca
    37921 taaaaaggtt atcatgttcg cttgtcaagg ttaacgattt tttcccgaat gtaaatttga
    37981 atcgatttag atttgccata aaattcacct cacgatatta taccaaaatt cgctaatttt
    38041 gtcagttttt acaaatttta ctgcttttgt ggtacaatag aaactatggc aagtatcaca
    38101 ctcacaccaa gcgaaaagga tattcaggct tttcttgaac actatcaaac cagtctggct
    38161 cctagcaaga atccctatat ccgctacttt ttgaaactac ctcaagcaac ggtttctatc
    38221 tatacttctg gaaaaatctt gcttcagggt gaaggggctg aaaaatacgc cagtttcttt
    38281 ggctatcaag ctgtagagca aaccagcgga caaaatcttc ctttaattgg gacagatgag
    38341 gtgggaaatg gttcctactt tggtgggctt gcagttgtgg ctgcctttgt cacacctgac
    38401 cagcacgact ttttacgaaa actcggtgtg ggggattcta agactctgac cgaccaaaag
    38461 atccgtcaga ttgctcctat tctcaaggaa aaaattcagc accaggtact ccttctctca
    38521 cccagcaagt acaacgaggt catcggagac cgctacaatg ctgtttcggt taaggttgcc
    38581 ctccataatc aggctatcta tctcctcctt caaaaaggtg ttcagcctga gaaaattgtg
    38641 attgatgcct ttaccagtgc taaaaattat gacaagtact tggcacaaga ggccaatcgt
    38701 ttcagcaatc ctatcagctt agaagaaaag gctgagggca aatacttggc tgtcgcagtt
    38761 tcttctgtca ttgcgcgtga tctctttctg gaaaatcttg aaaatctggg acgagaactg
    38821 ggttatcagc ttccaagtgg agctggaacg gcttctgaca aggtggctag ccagattttg
    38881 caagcctatg gtatgcaggg actcaatttc tgcgccaaat tgcactttaa aaacactgaa
    38941 aaagcgaaaa aacgcttaga aaggtaagtt atgaattcat ttaaaaattt cttaaaagag
    39001 tggggactgt tcctcctaat tctgtcatta ctagctttga gccgtatctt tttttggagc
    39061 aatgttcgcg tagaaggaca ttccatggat ccgaccctag cggatggcga aattctcttc
    39121 gttgtaaaac accttcctat tgaccgtttt gatatcgtgg tggcccatga ggaagatggc
    39181 aataaggaca tcgtcaagcg cgtgattgga atgcctggcg acaccattcg ttacgaaaat
    39241 gataaactct acatcaatga caaagaaacg gacgagcctt atctagcaga ctatatcaaa
    39301 cgcttcaagg atgacaaact ccaaagcact tactcaggca agggctttga aggaaataaa
    39361 ggaactttct ttagaagtat cgctcaaaaa gcccaagcct tcacagttga tgtcaactac
    39421 aacaccaact ttagctttac tgttccagaa ggagaatacc ttctcctcgg agatgaccgc
    39481 ttggtttcga gcgacagccg ccacgtaggt accttcaaag caaaagatat cacaggggaa
    39541 gctaaattcc gcttctggcc aatcacccgt atcggaacat tttaagaaac ctaagaggcc
    39601 gagaatcacc aatctcagcc tcttcttcta tcgtgagaaa atgattggta actatctaaa
    39661 cttaccagaa cagaaacacc tcaactctca cctattcatg caaaggaatt ttatggaagt
    39721 ttatttttca ggaaccattg aacggattat ttttgaaaat cccagcaatt tttatcgcat
    39781 cctcctccta gaaatcgacg atacggacgc agaggatttt gatgattttg aaatcattgt
    39841 cacaggaacc atggctgatg taattgaggg cgaagactat actttttggg ggcaaattgt
    39901 ccagcactcc aagtatggag aacaactgca aatcagtcgt tatgatcgcg caaaaccaac
    39961 tagtaagggc ttggtcaagt acttttcaag tagccatttc aaggggattg gtctcaagac
    40021 agctcagaaa atcgtggata cctatggcga aaataccatt gacgaaattt tgcaacaccc
    40081 agaaaagtta gaaggcatcg caggactctc tgccaaaaat cgcgaggctt tcgtctccac
    40141 tctccgtctc aactacggaa cggagatggt tttgtccaaa ctagccaact acggcattcc
    40201 caacaaacta gcctttcaga ttcaagactt ttacaaggaa gaaacccttg atgtggttga
    40261 aaattatccc taccagctgg ttgaggatat caagggtttg ggctttacca ttgctgacca
    40321 actagctgag gaactaggca tcgaaagtca ggctcctgaa cgcttccgcg ccggtctagt
    40381 tcacagtctt tttcaggcct gtatggaaac aggggacacc tatgttgaag cacgggattt
    40441 gctggaacaa acccttactc tccttgagtc ttcccgtccc gtggaactag accccagcca
    40501 agttgcccaa gagctctcct acctgatcga agaagacaag gttcagcaga ttgataccaa
    40561 gatctttgac aacagcctct ttttcgctga ggaaggcatc cgcagtcact tggttcgtat
    40621 ccttgaaaaa ggaaaacaga aaagtcatga tttaaaaacc attcaaaaac atatcactac
    40681 tatcgagaaa gagcttggaa ttgagtatga taacattcaa aaacaggcta tctgtgatgc
    40741 tatccagaat aaggtcttta tcctgacagg tggacctggt actggtaaga caactgttat
    40801 caatgggatc atcgctgttt acgccctgtt agagggactt gacctcagga agaaaagcaa
    40861 cctgcccatt cttcttgctg ctccaactgg tcgagctgct cgtcgcatga atgaattgac
    40921 aggtttgcct agcgcgacca tacaccgcca cttgggaatg acaggtgacg atgataccag
    40981 tcatctggaa gattacctag atgctgactt tatcatcgtg gatgaattct ctatggtgga
    41041 tacttggctg gccaatcaac tcttctccaa tatctcttct aacagtaaga tcctcatcgt
    41101 aggtgacagt gatcagctac cttctgtcag tcctggacag gttctagcgg atctgcttca
    41161 tattcctttg attcctcaga ctcgcttgga aaaaatttat cgacaaagcg aagaatcaac
    41221 catcgtcacc ctagctagtc agattcgaca gggcatcttg ccagctgatt tcacccaaaa
    41281 aaaagctgac cgttcctact ttgaaattgc tagtggccat attcctgcca ccattgaaaa
    41341 aatcttaggt gccgccctca gaaatggtat tcctgcccgt gatatccaag ttctggctcc
    41401 tatgtaccga gggacggcag ggattgatgc tatcaatcag ctcatgcaag acctgctcaa
    41461 tcccccacaa aaagatcaac tcagttttga agctcctcag tgccactatc gtaagggaga
    41521 caaggtcatt catttggtta acgatgctga aatcaatgtc tttaatgggg atttaggagc
    41581 tatcacagac ctgattcctg gtaaatacac cgaatcgaaa caagacgaga ttgtcattga
    41641 ttttgatggt aatgaagtct cttacccccg taacgaatgg tacaagattc gcttggccta
    41701 tgccatgagt attcataagt ctcagggaag tgagttccca gttgtcatcc taccgattac
    41761 tagtgctagc cgacgtatgc tggagcgaaa tctcatctac acagccatta cacgtgccaa
    41821 aagcaaactc atcttactag gcgaattaca agccttcgac tatgctaccc aacacatcgg
    41881 aactgcccga aaaacctatc tgattgaacg cttcagtgat ctactggaga atgttgaaga
    41941 aaagcaacaa gctgtctctg aaacagtcac atcaagtgcc tctgaacaat cctacatcct
    42001 aaccgaagaa aactgggaca gcattccagc catgattggg attacagaca cagacctcaa
    42061 agagattttt ggaaaatagt gcatcagaaa aaccaccaat tcaggtgggt tttctgttta
    42121 ttaagattat tttactgttg ctgtgcttgt aatcaattca acagcttttt tgatagtgat
    42181 atcatgtttc aacatgtcag ctgaaagcaa gttttgaact tgtgcaactt ccatgttgta
    42241 gtctgctgcc aattgctcaa cttctttttg gatttcttct tctgaagcat caaatccttc
    42301 agctttggca actgcttcga taacaaggtt agtcttagta cgtgactcag cttctgcttg
    42361 gtattggttg tgaaggtctt cttgagtagt tccagtgatt tggaagtaca tgtcagggtt
    42421 gatcccttga cgttgcaagt tcccaaggaa ttcatttact gaacggtgaa cttcttcgtg
    42481 gatcatttct tctggaagtt ctacgatttc agcattttct acagctgtat caattgctgc
    42541 accttcaact gcatctttgt aagcttcttc tttagcagta gccaattctt tgcggtattt
    42601 ttctttcaag tcagcaagtg tttcaacttc ttcatcaatg tcttttgcaa gttcatcgtc
    42661 aagagctgga acttctttag cttttacttc gtggatagtt gtcacgaatt tagcttcttt
    42721 acctgcaagg tcttctgctt ggtagtcttc tgggaatgtt acgataacat caacggtttc
    42781 gccagctgag tgacctacca attggtcttc gaaaccaggg atgaattgac ctgaaccaag
    42841 tccaagtgag aagttttcac cttttccacc gtcaaattca acaccgtcga tagaaccaac
    42901 gaagtcgatc acaacagtgt cgccgttttc agcagcagct tccttgataa ccaattcagc
    42961 cagattgttg cgttcgcgtt cgatacgctc ttcaacatca gcgtcagtta cttctttttc
    43021 tacatcaact gatacttcaa ggtttttgta gtcacccaat tttacttcag gttttgtaac
    43081 gacttcagca gtgataaccc agtcttgacc tttttccatt gaagttacgt caatttttgg
    43141 ttgggcaacc acttcaagac cagcttcttt tacagctgct tcataagcgt ttggcaaaag
    43201 agcgttcata acgtcttggt aaagtgattc ttcaccaaat tttttatcga agataggacg
    43261 tggaaggtga cctttacgga aacctggaac attaagagat ttcttcactg acttgaagac
    43321 acggtccaat tctggtttga tttggtcttg agagatagtg aaagtcaaga caccacggtt
    43381 tgtttctttg ttttcaaatg atacagacat tctgtcattt ctccttaaaa ttttttaaat
    43441 acagtctatt ataacatttt ctataaataa aatctagact aatgcagcca attatagaca
    43501 acaagccttt ttcctaacta
//
LOCUS       DAVMBH010000013        40083 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVMBH010000013 DAVMBH010000000
VERSION     DAVMBH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.013"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            789..2942
                     /locus_tag="VYP30_000818"
     CDS             789..2942
                     /locus_tag="VYP30_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1807850.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2955..4304
                     /locus_tag="VYP30_000819"
     CDS             2955..4304
                     /locus_tag="VYP30_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1807851.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4474..5181
                     /locus_tag="VYP30_000820"
     CDS             4474..5181
                     /locus_tag="VYP30_000820"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1807852.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5383..9108
                     /locus_tag="VYP30_000821"
     CDS             5383..9108
                     /locus_tag="VYP30_000821"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1807853.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9201..10643
                     /locus_tag="VYP30_000822"
     CDS             9201..10643
                     /locus_tag="VYP30_000822"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1807854.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10680..11702
                     /locus_tag="VYP30_000823"
     CDS             10680..11702
                     /locus_tag="VYP30_000823"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1807855.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11699..12244
                     /gene="purN"
                     /locus_tag="VYP30_000824"
     CDS             11699..12244
                     /gene="purN"
                     /locus_tag="VYP30_000824"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1807856.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12328..12837
                     /locus_tag="VYP30_000825"
     CDS             12328..12837
                     /locus_tag="VYP30_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1807857.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12862..14409
                     /gene="purH"
                     /locus_tag="VYP30_000826"
     CDS             12862..14409
                     /gene="purH"
                     /locus_tag="VYP30_000826"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1807858.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14531..15793
                     /gene="purD"
                     /locus_tag="VYP30_000827"
     CDS             14531..15793
                     /gene="purD"
                     /locus_tag="VYP30_000827"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1807859.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTIADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            16196..16684
                     /gene="purE"
                     /locus_tag="VYP30_000828"
     CDS             16196..16684
                     /gene="purE"
                     /locus_tag="VYP30_000828"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1807860.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16671..17762
                     /gene="purK"
                     /locus_tag="VYP30_000829"
     CDS             16671..17762
                     /gene="purK"
                     /locus_tag="VYP30_000829"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1807861.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPVSRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSQDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENPSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            17772..17999
                     /locus_tag="VYP30_000830"
     CDS             17772..17999
                     /locus_tag="VYP30_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1807862.1"
                     /translation="MIQIIVNTFIEKYKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18062..19360
                     /gene="purB"
                     /locus_tag="VYP30_000831"
     CDS             18062..19360
                     /gene="purB"
                     /locus_tag="VYP30_000831"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1807863.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCNKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19415..23353)
                     /gene="strH"
                     /locus_tag="VYP30_000832"
     CDS             complement(19415..23353)
                     /gene="strH"
                     /locus_tag="VYP30_000832"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1807864.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSHLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGSPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAELVVAGLMSTLAAYGLTKRKED"
     gene            complement(23668..24384)
                     /locus_tag="VYP30_000833"
     CDS             complement(23668..24384)
                     /locus_tag="VYP30_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1807865.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24733..26520
                     /locus_tag="VYP30_000834"
     CDS             24733..26520
                     /locus_tag="VYP30_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1807866.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPCEGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKEENL"
     gene            26517..26993
                     /locus_tag="VYP30_000835"
     CDS             26517..26993
                     /locus_tag="VYP30_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1807867.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILGGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27021..27926
                     /locus_tag="VYP30_000836"
     CDS             27021..27926
                     /locus_tag="VYP30_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1807868.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27913..28728
                     /locus_tag="VYP30_000837"
     CDS             27913..28728
                     /locus_tag="VYP30_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1807869.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28735..29139
                     /locus_tag="VYP30_000838"
     CDS             28735..29139
                     /locus_tag="VYP30_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1807870.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29438..30604
                     /locus_tag="VYP30_000839"
     CDS             29438..30604
                     /locus_tag="VYP30_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1807871.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30720..31757
                     /locus_tag="VYP30_000840"
     CDS             30720..31757
                     /locus_tag="VYP30_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1807872.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31964..32818
                     /locus_tag="VYP30_000841"
     CDS             31964..32818
                     /locus_tag="VYP30_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1807873.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            32968..33225
                     /locus_tag="VYP30_000842"
     CDS             32968..33225
                     /locus_tag="VYP30_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1807874.1"
                     /translation="MTNSKYITCLKRSEGQLRGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33438..33521)
                     /locus_tag="VYP30_000843"
                     /pseudo
     CDS             complement(33438..33521)
                     /locus_tag="VYP30_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
     gene            complement(33555..33647)
                     /locus_tag="VYP30_000844"
                     /pseudo
     CDS             complement(33555..33647)
                     /locus_tag="VYP30_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33683..33979)
                     /locus_tag="VYP30_000845"
                     /pseudo
     CDS             complement(33683..33979)
                     /locus_tag="VYP30_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(33969..34130)
                     /locus_tag="VYP30_000846"
     CDS             complement(33969..34130)
                     /locus_tag="VYP30_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1807875.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            34200..34964
                     /locus_tag="VYP30_000847"
     CDS             34200..34964
                     /locus_tag="VYP30_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1807876.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(35198..35356)
                     /locus_tag="VYP30_000848"
     CDS             complement(35198..35356)
                     /locus_tag="VYP30_000848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807877.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            35574..36953
                     /locus_tag="VYP30_000849"
     CDS             35574..36953
                     /locus_tag="VYP30_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1807878.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36967..37632
                     /locus_tag="VYP30_000850"
     CDS             36967..37632
                     /locus_tag="VYP30_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1807879.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37746..37841
                     /locus_tag="VYP30_000851"
                     /pseudo
     CDS             37746..37841
                     /locus_tag="VYP30_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            37987..38526
                     /locus_tag="VYP30_000852"
     CDS             37987..38526
                     /locus_tag="VYP30_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1807880.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            38593..39003
                     /locus_tag="VYP30_000853"
     CDS             38593..39003
                     /locus_tag="VYP30_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1807881.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39119..>40083
                     /gene="pavB"
                     /locus_tag="VYP30_000854"
     CDS             39119..>40083
                     /gene="pavB"
                     /locus_tag="VYP30_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1807882.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKSTVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLE"
BASE COUNT        11056 a         7771 c         9336 g        11920 t
ORIGIN      
        1 actgatgaag tcgggaattt tagatgaaca aattgataaa ttatctgaac tatctaatct
       61 ttttacaatt aaaatagaaa caatattgac agtgatttct gttgttttca catttatagc
      121 aactcttatt gaatatggat tttctctctt tctgattaca ttattttttg ataagaataa
      181 gaggaacttt ggagatattc ttttatctaa aaatataacc ttaagtttta gcattttact
      241 ttgttattta tttaatccat cggatataaa gtttgcctat ttcagcgtat tgacagtatt
      301 actaattggg ataacaaatt atgcgagatt taaaaattta agattgacag tagtgttttc
      361 tgtaccattt ttatttaatg ctataatgtc tattataaat agtttttaga aatactaaaa
      421 tttttttctt tacttaataa tgatatgaaa tcatttcggt tttgttaact tgtaattctt
      481 atattttcta ggtagaacgt ttgttctgcc tattttttta tccaaaaagt gcagttggga
      541 gggagatagg ctcatttggg aaggaagtcc agtttttgtt tagtgattgg ggtaagatag
      601 ttgttatcag atgagtttat actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct
      661 tgccgtatat atgtgactga cttcgtcagt cctatctaca acctcaaaac agtgttttga
      721 gcagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt agggaaaagg
      781 agatgaatat gaaatttggg aaacgtcact atcgtccgca agtggatcag atggactgcg
      841 gtgtagcttc attagccatg gtttttggct actatggtag ttattatttt ttggctcact
      901 tgcgagaatt ggctaagacg accatggatg ggacgacggc tttgggcttg gtcaaggtgg
      961 cagaggagat tggttttgag acgcgagcca ttaaggcgga tatgacgctt tttgacttgc
     1021 cggatttgac ttttcctttt gttgcccatg tgcttaagga agggaaattg ctccactact
     1081 atgtggtgac tgggcaggat aaggatagca ttcatattgc cgatccagat cccggggtga
     1141 agttgactaa actgccacgt gagcgttttg aggaagaatg gacaggagtg actcttttta
     1201 tggcacctag tccagactat aagccttata aggaacaaaa aaatggtctg ctctctttta
     1261 tccctatatt agtgaagcag cgtggcttga ttgccaatat cgttttggca acactcttgg
     1321 taaccgggat taacattgtg ggttcttatt atctgcagtc tatcattgat acctatgtgc
     1381 cagatcagat gcgttcgaca ctagggatta tttctattgg gctagtcatc gtctacatcc
     1441 tccagcaaat cttgtcttac gctcaggagt atctcttgct tgttttgggg caacgcttgt
     1501 cgattgacgt gattttgtcc tatatcaagc atgtttttca cctccctatg tccttctttg
     1561 cgacacgcag gacaggggag atcgtgtctc gttttacaga tgctaacagt atcatcgatg
     1621 cgctggcttc gaccatcctt tcgattttcc tagatgtgtc aacggttgtc attatttccc
     1681 ttgttctatt ttcacaaaat accaatctct ttttcatgac tttattggcg cttcctatct
     1741 acacagtgat tatctttgcc tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg
     1801 aagccaatgc ggttctgtct tcttctatca ttgaggacat caacggtatt gagactatca
     1861 agtccttgac cagtgaaagt cagcgttacc aaaaaattga caaggaattt gtggattatc
     1921 tgaagaaatc ctttacctat agtcgagcag agagtcagca aaaggctctg aaaaaggttg
     1981 cccatctctt gcttaatgtc ggcattctct ggatgggggc tgttctggtc atggatggca
     2041 agatgagttt ggggcagttg attacctata ataccttgct ggtttacttt accaatcctt
     2101 tggaaaatat catcaatctg caaaccaagc ttcagacagc gcaggttgcc aataaccgtc
     2161 taaatgaagt gtatctagta gcttctgagt ttgaggagaa gaaaacagtt gaggatttga
     2221 gcttgatgaa gggagatatg accttcaagc aggttcatta caagtatggc tatggtcgag
     2281 acgtcttgtc ggatatcaat ttaaccgttc cccaagggtc taaggtggct tttgtgggga
     2341 tttcagggtc aggtaagacg actttggcca agatgatggt taatttttac gacccaagtc
     2401 aaggggagat tagtctgggt ggtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc
     2461 agtacatcaa ctatctgcct caacagccct atgtctttaa cggaacgatt ttggagaatc
     2521 ttcttttggg agccaaggag gggacgacac aggaagatat cttacgggcg gtcgaattgg
     2581 cagagattcg agaggatatc gagcgcatgc cactgaatta tcagacagaa ttgacttcgg
     2641 atggggcagg gatttcaggt ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga
     2701 cagatgcgcc ggtcttgatt ttggatgagg cgactagcag tttggatatt ttgacagaga
     2761 agcggattgt cgataatctc attgctttgg acaagacctt gattttcatt gctcaccgct
     2821 tgactattgc tgagcggaca gagaaggtgg ttgtcttgga tcagggcaag attgtcgaag
     2881 aaggaaagca tgctgatttg cttgcacagg gtggctttta cgcccatttg gtcaatagct
     2941 agaaagagga gaggatgaaa ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt
     3001 accataattt ttccagtagt gtgattgtac ccatggccct tctgctcgtg tttttacttg
     3061 gctttgcaac tgttgcagaa aaggagatga gtttgtccac tagagctact gtcgaaccta
     3121 gtcgtatcct tgcaaatatc cagtcaacta gcaacaatcg tattcttgtc aatcatttgg
     3181 aagaaaataa gctggttaag aagggggatc ttttggttca ataccaagaa ggggcagagg
     3241 gtgtccaagc ggagtcctat gccagtcagt tggacatgct aaaggatcaa aaaaagcaat
     3301 tggagtatct gcaaaagagc ctgcaagaag gggagaacca ctttccagag gaggataagt
     3361 ttggctacca agccaccttt cgcgactaca tcagtcaagc aggcagtctt agggctagta
     3421 catcgcaaca aaatgagacc atcgcgtccc agaatgcagc agctagccaa acccaagccg
     3481 aaatcggcaa cctcatcagt caaacagagg ctaaaattcg cgattaccag acagctaagt
     3541 cagctatgga aacaggtgct tccttggcca gtcagaatct agcctactct ctttaccagt
     3601 cctacaagtc tcagggcgag gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg
     3661 aagcacagat ttctcagtta gaatctagtc ttgctactta ccgtgtccag tatgcaggtt
     3721 caggtaccca gcaagcctat gcgtcagggt taagcagtca attggaatcc cttaaatccc
     3781 aacatttggc aaaggttggt caggaattga cccttctagc ccagaaaatc ttggaggcag
     3841 agtcaggtaa gaaggtacag ggaaatcttt tagacaaggg gaaaattacg gcgagtgagg
     3901 atggggtgct tcatcttaat cctgagacca gtgattctag catggttgca gaaggtgccc
     3961 tactagccca actttatcca tctttggaaa gagaagggaa agccaaactc acagcctatc
     4021 taagttcaaa agatgtagca agaatcaagg tcggtgattc tgttcgctat actacgactc
     4081 atgatgccgg gaatcaactt ttcctagatt caactattac aagtattgat gcgacagcta
     4141 ctaagactga gaaagggaat ttctttaaaa tcgaggcgga gactaatcta acttcggagc
     4201 aggctgaaaa acttaggtac ggggtggaag gccgcttgca gatgattacg ggcaagaaaa
     4261 gttatctacg ttattatttg gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga
     4321 gttaaataat ttttaaactg tgagaaagat tcttcttgca gttttttctt tacaattttt
     4381 gaaaaacatc tactatttat tcggttaaat tcttgtgttt tttggttttt tgtggtaaaa
     4441 tttgctcaag taatacgaaa ggcgaacttt aaaatgtcaa aacaattgat ctattcggga
     4501 aaagctaaag atatctatac aactgaggat gaaaatctta ttatttcaac ttacaaggac
     4561 caggcgactg ctttcaacgg tgtcaagaag gagcagattg caggtaaggg agtcttgaat
     4621 aatcagatct catcttttat ttttgagaaa ttaaatgcgg ctggtgtggc gactcacttt
     4681 gtggagaaac tttcagacac ggaacaactc aataaaaagg ttaagattat tcctttggaa
     4741 gtcgtgctcc gcaactatac tgctggttcc ttttcaaaac gttttggtgt ggatgaggga
     4801 atcgccttgg agactccgat tgtcgaattt tactacaaaa atgatgattt ggatgatcca
     4861 tttatcaatg atgagcatgt gaaattccta cagattgcgg gtgaccagca gattgcctac
     4921 ttgaaggaag aaacgcgtcg tatcaatgaa ctattgaaag tctggtttgc tgagattggg
     4981 cttaaattga ttgactttaa gctagagttc ggttttgaca aggatggcaa gattatcttg
     5041 gcagacgaat tttcaccaga taactgccgc ttgtgggacg ctgatggcaa ccacatggat
     5101 aaggatgttt tccgtagagg attgggagaa ctaaccgacg tttatgagat tgtttgggaa
     5161 aagttgcagg aattgaaata atctgtttgc aacggaaaac cttcgtctct caactaaaag
     5221 gactcaggct gaaaaggtcc cccagacctt ttcactctgt agagaactag gtgaactaac
     5281 agatgtttac gaaattgtct gggaaaagtt gcagggttta aaataacaac ctcaaggctg
     5341 tttgggaata ttgcaagagc tgaaataaag gaataagaat tgatggataa acgtattttt
     5401 gttgaaaaaa aggctgattt tcaggtcaag tcagagagtt tggttagaga gctccagcac
     5461 aacttgggac tgtcaagctt gaaaagtatt cgtattgtgc aagtatatga tgtatttgac
     5521 ttggctgagg acttgtttgc acctgcagag aagcacattt tctctgagca gggaaccgac
     5581 catgttttag atgaagtatc tgtgcaggcg gatcttgcta actatgcttt ctttgccatt
     5641 gaaagtctgc cagggcagtt tgaccagcgt gcagcttcgt cacaggaagc cttgcttttg
     5701 ttgggaagtt cgagtgacgt gacagtcaac acagcccaac tttacttggt gaataaagat
     5761 attgatgcga ctgagttgga agctgtcaaa aactacctgc tcaatccagt tgattctcgt
     5821 ttcaaggata tcacgacagg gattgccaag caggagtttt cagagtcaga caagaccatt
     5881 ccaaaattga ctttctttga aagctataca gcagaagact ttgctcgcta caaggccgag
     5941 caagggatgg ccatggaagt ggatgatttg ctctttatcc aagactactt taagtcaatc
     6001 gggcgcgtgc caactgagac tgaactcaag gttttggaca cttactggtc tgaccactgc
     6061 cgtcatacga cttttgagac agagttgaaa cacatcgact tttcagcttc taaatttcaa
     6121 aagcaattgc agtcaaccta tgacaagtat attgccatgc gcgaggagtt aggtcggtct
     6181 gaaaaaccac aaaccttgat ggatatggcg actattttcg gtcgttatga gcgtgctaac
     6241 ggacgattgg atgatatgga agtctctgac gaaatcaatg cctgctcagt tgaaattgaa
     6301 gtggatgttg atggtgtcaa ggaaccttgg ctcctcatgt ttaaaaatga aacccacaac
     6361 catccaacag aaattgagcc atttggtgga gcggctacct gtatcggtgg agctattcgt
     6421 gatccgttgt caggccgttc ctatgtttac caagccatgc gtatttcagg tgctggtgat
     6481 attacagcac cgatttcgga aactcgtgct gggaaattgc cacaacaagt catttctaaa
     6541 acagcagctc atggttattc ttcatatggt aaccagattg ggcttgccac aacctacgtt
     6601 cgtgaatact tccacccagg ctttgtagct aaacgtatgg aacttggtgc cgttgttggt
     6661 gcggctccca agggcaatgt tgtccgtgaa aaacctgaag caggtgatgt gatcatcctt
     6721 ctcggaggca aaacaggtcg tgatggtgtc ggtggtgcga cgggctcttc taaggttcaa
     6781 acagttgagt ctgtagagac tgctggtgct gaggttcaaa aaggaaatgc catcgaagaa
     6841 cgcaagattc agcgcctctt ccgtaatggc aatgtcactc gtctgatcaa gaagtccaat
     6901 gactttgggg caggcggcgt ctgtgtggct atcggtgaat tggcagacgg tcttgaaatc
     6961 gacctcaaca aggtgcctct taaataccag ggcttgaatg gtacagaaat tgccatctct
     7021 gaatcacaag aacggatggc ggtcgtggtt cgtcctgaag atgtggatgc cttcgttgcc
     7081 gaatgtaaca aagaaaatat tgatgctgtt gtggtagcga cagtaactga aaaaccaaat
     7141 cttgtcatgc actggaatgg tgagacaatc gttgacttgg agcgtcgttt ccttgacacc
     7201 aatggtgtgc gcgtggttgt cgatgccaaa gttgtggaca aggatgtcaa actcccagaa
     7261 gagcgtcaaa catctgctga aacactggaa tcagataccc ttacggttct atctgacctc
     7321 aaccatgcaa gtcaaaaagg attacagact gtctttgact gctctgttgg acgctcaacg
     7381 gttaatcacc cacttggtgg tcgttaccaa ctcacaccaa ctgaggcatc tgtgcagaaa
     7441 ttgccagttc aacacggtgt gactcatact gcgtcggtca ttgctcaagg tttcaaccca
     7501 tatgtagctg aatggtctcc ataccacggt gctgcttacg cggttatcga agcaactgct
     7561 cgtttggtgg ctgctggtgc caactggtct aaggctcgtt tctcttacca agaatatttc
     7621 gagcggatgg acaagcaagc agagcgtttt ggtcagccag tagccgccct tctaggctct
     7681 attgaagctc agattcaact tggcttgcca tctatcggtg gtaaggactc catgtctggt
     7741 acctttgaag aattgaccgt tccgccaacc ttggttgcct ttggggtgac gacggcagat
     7801 agccgtaagg tgctctctcc agaatttaaa gctgttgggg aaaatatcta ctacatccca
     7861 ggtcaagccc tctctgcaga gattgatttt gacttgatta agaaaaattt tgctcagttt
     7921 gaagcaagcc aagctgacca taaagtgaca tctgcatcag ctgtcaaata cggtggtgta
     7981 gttgaaagtt tggctcttgc tacctttgga aactatattg gtgcagaggt gaccttgcct
     8041 gaacttaaaa cagctttgac agctcaatta ggcggctttg tcttcacatc tcctgaagaa
     8101 attgctggag tagagaagat tggacaaacg aaagcagact ttacactgac tgtcaacggt
     8161 gtgaagctag atggacacaa gcttgacagt gcatttcaag ggacattgga agaagtttac
     8221 ccaacagaat ttacccaagc gaaagaacta gaagaagtac cagctgtggc atcagatgtt
     8281 gtgattaaag ccaaagaaaa ggttgaaaaa cctgtggttt acatcccagt ctttccagga
     8341 accaactcag aatacgattc agctaaggcc ttcgaaaaag aaggtgcaga ggtcaatttg
     8401 gtgccattcg tgaccttgaa tgaagaagct attgtcaagt cagttgaaac tatggttgac
     8461 aatatcgaca agactaatat tctcttcttt gccggtggat tctcggctgc ggatgaacca
     8521 gatggttcag ctaagtttat cgtcaatatc ctgcttaatg aaaaagtgcg tgtggctatt
     8581 gatagcttta tcgcccgtgg tggcttgatt atcggtattt gtaatggatt ccaagcctta
     8641 gtcaaatcgg gtctcctacc atacggaaac tttgaagatg ctaacagtac tagtccaacc
     8701 ctcttctaca atgatgccaa ccaacacgtg gccaagatgg tggaaactcg cattgccaat
     8761 accaactcac catggttggc tggtgtgcaa gtgggcgata tccacgctat tcctgtttcg
     8821 cacggtgaag ggaagtttgt cgtgacggct gaggaatttg cagagctccg tgacaatgga
     8881 caaattttca gccaatacgt tgactttaac ggtaaaccaa gtatggattc taagtacaat
     8941 ccgaatggtt ctgtccatgc catcgaagga attaccagca agaatggtca aatcatcggt
     9001 aagatgggcc actcagaacg ttatgaggat ggtcttttcc aaaatatccc aggcaataaa
     9061 gaccaacacc tgttcgcatc agcggttaaa catttcactg gaaaataaga cttacagatt
     9121 ttctaataga tagtatcagt aatgtaaaag tcatgtaaat ctagctcttg atgattacaa
     9181 atgaaaatta ggtataaaaa atgacatacg aagtaaaatc tcttaatgaa gaatgtggtg
     9241 ttttcggtat ttggggacat ccagatgctg ctaagttgac ctattttgga ctccacagtc
     9301 ttcaacaccg tggtcaggag ggggcaggaa tcctctccaa cgatcaagga caactgaagc
     9361 gccatcgtga catggggctt ttatcagaag ttttcagaaa tccagctaat ttggataaat
     9421 tgacaggagc tggtgcgatt gggcatgtgc gttatgcgac tgctggcgaa gcttctgtag
     9481 ataacatcca gcccttcctc ttccgttttc acgatatgca gtttggcttg gctcataatg
     9541 gaaatctgac caatgcagcc tctctcaaga aagaactgga acaaagagga gcaattttca
     9601 gcgcgacttc ggactctgaa atcttggctc acctcattcg tcgcagtcat aatcctagcc
     9661 tgatgggcaa aatcaaggaa gcgctcagcc ttgtcaaagg tggttttgcc tatatcttgc
     9721 tgtttgagga caagttgatt gcggctcttg accctaatgg ctttcgtccg ctttctatcg
     9781 ggaaaatggc caacggagcg gtggttgttt cctctgaaac ctgtgctttt gaggtcattg
     9841 gtgccgagtg gattcgtgat ttgaagccag gtgagattgt gatcattgat gacgagggca
     9901 ttcagtatga cagctataca gatgataccc agttggcgat ttgttctatg gagtatatct
     9961 actttgcccg ccctgattct aatatccacg gtgtcaatgt ccatacggca cgtaagagaa
    10021 tgggagcgca attggcgcga gaatttaagc atgaggcaga tattgtagtt ggtgtgccca
    10081 attcttccct aagcgcggct atgggatttg cggaagaatc aggcttacca aatgaaatgg
    10141 gtctgatcaa aaaccaatac acccagcgaa cttttatcca accgactcaa gaattgcggg
    10201 agcaaggagt gcggatgaaa ctgtctgctg tttcgggtgt tgtcaaaggc aaacgtgtgg
    10261 tcatggtgga tgattccatt gtacgtggaa caacctctcg tcgtatcgtt cagctcttga
    10321 aagaagcggg tgcgactgag gttcacgttg ccattggaag tcctgcacta gcgtatccat
    10381 gtttctacgg gattgatatc cagacccgtc aggagctgat tgcagccaat catacggtcg
    10441 aagaaactcg ccaaatcatt ggtgcggaca gtctgactta tctttcaatt gatggcttga
    10501 ttgagtcgat tggtatcgaa acagatgcgc cgaacggtgg tctctgtgtc gcttactttg
    10561 acggtgacta cccaacgcct ctctatgact acgaagaaga ctatcgtaga agtttggaag
    10621 aaaagaccag tttttacaag taggcgacag attctccatt aaagaaaagg aaaaaacaaa
    10681 tgacaaataa aaatgcatat gcccagtcgg gtgtggatgt tgaagcgggt tatgaagttg
    10741 ttgaacggat taaaaagcac gtggcccgta cggagcgtgc aggtgtcatg ggagctcttg
    10801 gtggctttgg tggtatgttt gacctttcca agactggggt taaagaaccc gtcttgattt
    10861 cagggactga cggtgtcgga accaagctca tgttggctat caagtacgac aagcacgata
    10921 ccatcgggca ggactgtgtg gccatgtgtg tcaacgacat cattgctgca ggtgcggaac
    10981 ccctctattt tctcgactac gtagcgacag ggaagaatga accagctaag ctagaacaag
    11041 tggttgctgg tgtggcagaa ggttgtgtgc aggctggtgc tgccctcatc ggtggggaaa
    11101 cggctgaaat gccgggcatg tacggcgaag acgactatga cttggctggt tttgcggtcg
    11161 gtgtggctga aaaatctcaa atcattgacg gttcaaaggt ggtagaggga gatgttcttc
    11221 tcggacttgc ttcaagtggg attcactcaa atggttactc tttggttcgt cgtgtctttg
    11281 cggattacac aggtgaggaa gtcctaccag aattggaagg caagaaactt aaggaagttc
    11341 tacttgagcc gactcgtatc tatgtcaagg ctgtcttgcc gctcatcaaa gaagagttgg
    11401 tcaacggcat tgcccacatc acaggtggtg gctttatcga aaatgtccct cgtatgtttg
    11461 cagatgacct agctgctgaa attgatgaaa gcaaagttcc agtgcttcca attttcaaag
    11521 cccttgaaaa atatggtcag attaaacacg aagaaatgtt tgaaatcttc aatatgggtg
    11581 tgggacttat gttggcggtc agccctgaaa atgtagagcg tgtaaaagaa ttgttggatg
    11641 aagcagtcta tgaaattggt cgcatcgtca agaaagaaaa cgaaagtgtc attatcaaat
    11701 gaaaaaaata gcggtttttg cctctggtaa tggctcaaat tttcaggtga ttgccgaaga
    11761 atttccagtg gagtttgtct tttcagacca tcgtgatgcc tatgtgcttg agcgtgcaaa
    11821 gcagctcggc gttctgtcct atgcttttga actcaaggag tttgagagca agacagacta
    11881 cgaagcagcc cttgtcgaac tcttggaaga acaccagatt gacttggttt gcctagcagg
    11941 ctacatgaaa atcgttggac caaccttatt gtcggcttat gaaggtcgga ttgtcaacat
    12001 tcatccagcc tacttgccag aatttccagg agctcatggg attgaggatg cttggaatgc
    12061 tggcgtgggt cagtctggtg tgaccattca ctgggtggat tcgggtgtgg atacaggcca
    12121 ggtcatcaaa caggttcgtg tgccacgact agctgatgat accattgaca gatttgaagc
    12181 tcgcatccat gaagcagagt acaggttgta tccggaagta gtgaaggctc tatttacaga
    12241 ttgacttttt gatgattcat atgatatctt tgattttaaa ttggagtcag tgtttgttga
    12301 agacggcttc aaacggaggt atttgtaatg ttagaatcta aaaaaacaac tcgatatgta
    12361 ttttatgtct atctgatgtt attaacttgg ggaatcttat ttaagtttga aacaaatcct
    12421 gaatttatag catttttctt agctccaagg tatatcaatt ggattccatt ttcagaacca
    12481 ctaatagtcg atggaaaaat tgtttttgct gaaatgttat ttaatctgat ttcctttatt
    12541 ccattaggtg tttgtttccc tttgataaaa actaatttat ctagtttaag aatagtcggg
    12601 acaggtttct tgattagttt attgtttgag tgcttacagt atattttagc aataggtata
    12661 acagatataa cggatttgac tttaaatacg ctaggtgtct gtgtaggctt actgatttat
    12721 caaattttta taagagtgtt caaatcacag actagaaaat ggatcaatat cttaggtatg
    12781 cttagccttg gttttgctta tcttgtttta ctgttactgc atttaattgg tgtttaacta
    12841 atgattaaaa aggagaatat aatgactaaa cgcgtcttaa tcagcgtctc agacaaagcg
    12901 ggcattgttg aatttgccca agaactcaaa aaacttggtt gggagattat ctcaacaggt
    12961 ggaactaagg ttgcccttga taatgctggg gtggatacca ttgctatcga tgatgtgact
    13021 ggtttcccag aaatgatgga cggtcgtgtg aagaccctcc acccaaatat ccacggaggg
    13081 cttctcgctc gtcgtgactt ggatagccac ttggaagcgg ctaaggacaa caagattgag
    13141 ctcattgacc ttgtggtggt caacctttac ccatttaagg aaactatcct taaaccagat
    13201 gtgacttatg ctgatgcagt tgaaaatatc gatattggtg ggccgtctat gcttcgttca
    13261 gcagcgaaaa atcatgccag tgttacagtt gtggtagatc ctgctgacta cgctgtggtt
    13321 ttggacgaat tggcagcaaa cggcgaaacc tcttatgaaa ctcgccaacg tttagcagcc
    13381 aaagtatttc gtcacacagc ggcttatgac gccttgattg cagaatactt cacagctcaa
    13441 gtgggtgaaa gcaagcctga aaaactcact ttgacttatg acctcaagca accaatgcgt
    13501 tacggtgaga atcctcaaca agacgcggac ttttaccaga aagctttgcc tacagattac
    13561 tctattgctt cagccaaaca gctcaacggg aaagaattgt catttaataa tatccgtgat
    13621 gcagatgctg ctatccgtat catccgtgac ttcaaagata gtccaaccgt tgtggctctc
    13681 aaacacatga atccatgtgg aattggtcaa gctgatgaca tcgagactgc ttgggactac
    13741 gcttatgagt ctgacccagt atctatcttt ggtgggattg tcgtcctcaa ccgtgaggtg
    13801 gatgctgcga cagctgagaa gatgcacggc gttttcctcg aaatcatcat tgcaccaagc
    13861 tatacggatg aagcgctagc cattttgatc aataaaaaga aaaacttgcg tatccttgcc
    13921 ttgccattta atgctcaaga ggctagcgaa gtggaagcag aatacacagg tgtagtcggt
    13981 ggacttctcg tgcaaaatca agacgtggtc aaggaaagcc cagctgactg gcaagtggtg
    14041 accaaacgtc agccaaccga gacagaagcg actgctcttg agttcgcttg gaaggctatc
    14101 aagtacgtca aatcaaatgg tattatcgtg accaacgacc acatgacact tggtgttggt
    14161 ccaggtcaaa ccaaccgtgt ggcttctgtt cgccttgcca ttgaccaagc caaagatcgt
    14221 ctgaacgggg cggtccttgc ttcagatgcc ttcttcccat ttgcggataa cgtggaagaa
    14281 atcgccaaag caggaattaa ggccatcatc cagcccggtg gctctgtccg tgaccaagaa
    14341 tccatcgaag cagcggataa atacggcttg actatggtct ttacaggtgt gagacatttt
    14401 agacattaag aagataaaag ggaagaaaac agtttctttc cttttttggc ttaaaatgct
    14461 aactgaaaca agattaaaac gaactttttt gatataatgt tggtaaataa ttcgcaaaag
    14521 aggttgagga atgaaactgc ttgttgtcgg ttctggtggt cgtgagcatg cgattgctaa
    14581 aaagttactt gaatcaaaag acgtggaaaa agtctttgta gctcctggga atgatgggat
    14641 gactctggat ggtttggaat tggtaaatat ctctatttcc gaacattcta aattgattga
    14701 cttcgcaaag accaatgatg ttgcttggac ctttatcggt ccagatgatg cccttgctgc
    14761 tggtatcgtg gatgatttta accaagctgg acttaaggcc tttggtccga ctagggctgc
    14821 agcggagctg gagtggtcca aggatttcgc caaggaaatc atggtcaaat acggcgttcc
    14881 gacagcaaca tatggcacat tttcagattt cgaggaagcc aaggcctata tcgaaaagca
    14941 tggtgcgcct atcgtagtca aggcggatgg cttggcactt gggaagggtg tcgtcgttgc
    15001 tgagacggtt gagcaagcgg tcgaagccgc tcatgagatg cttttggaca ataaatttgg
    15061 tgactcaggt gcgcgcgtgg ttattgagga attccttgaa ggagaggaat tttcactctt
    15121 tgcctttgtc aatggtgata agttctacat catgccaacg gctcaggacc acaaacgtgc
    15181 ctatgatggc gacaaagggc ctaacacggg tggtatgggt gcctatgcgc cagtcccaca
    15241 cttaccacag agtgtagttg atacagcggt tgacaccatt gtcaagccag ttctagaagg
    15301 ggtgattaaa gaaggtcgcc cttatctggg agttctttac gcagggctta tcctgacagc
    15361 tgatggaccg aaagtcattg agttcaacgc tcggttcgga gatccagaaa ctcagattat
    15421 cttgcctcgc ttgacctctg actttgctca aaatatcaca gatatcctgg atagcaagga
    15481 gccaaatatc atgtggacgg acaagggtgt gactctgggt gtggttgtcg catccaaggg
    15541 ctacccgcta gactatgaaa ggggcgttga gttgccagcc aagacagaag gcgatgtcat
    15601 cacctactat gcaggggcta agtttgcgga aaatagcaga gcactgctct caaacggcgg
    15661 acgagtttat atgctcgtta ccatagcaga taccgtcaaa gaagcccaag ccagcatata
    15721 ccaagaacta taccaacaaa aaatagaagg actcttctac cgaacagata tcggaagcaa
    15781 ggcaattaag taaagatata agaataacgc gccgtagtcg ccaaacacga taatggtcgt
    15841 cgtggtgaaa agaccagaac agtgaatgtt ctggtcaggg ggaaacttgg agaccttagg
    15901 ctcaaagttt aggaatgaaa ccgaaggttt gcttccgcct ccatcaccta agaccattat
    15961 caaaaagaaa aataaaaatt cacaaaatac gttaatgatc gtatggtttg cgagcgttag
    16021 cgagctaata tagaacaatc accgccgttg tgaaagaacg attggatgat aatccaatcg
    16081 ttcagggaaa ttggaagacc ttgggtttcc aatttaggca tgagacacct ttggtggctg
    16141 ctgccgtccc tcacaagcta aggtgattgt tgaaaaagag gaaaaaggag aagaaatgaa
    16201 accagtaatt tccatcatca tgggctcaaa atccgactgg gcaaccatgc aaaaaacagc
    16261 agaagtccta gaccgcttcg gtgtagccta cgaaaagaaa gttgtttccg cacaccgtac
    16321 accagacctc atgttcaaac atgcagaaga agcccgtagt cgtggcatca agatcatcat
    16381 cgcaggtgct ggtggcgcag cgcatttgcc aggcatggta gctgccaaaa caacccttcc
    16441 agtcattggt gtgccagtca agtctcgtgc tcttagtgga gtggattcac tctattctat
    16501 cgttcagatg ccgggtgggg tgcctgttgc gaccatggct atcggtgaag ctggagcgac
    16561 taacgcagct ctctttgccc tccgtctcct ctctgtagaa gataagtcca ttgcggatgc
    16621 acttgccaac tttgctgaag aacaaggaaa aatcgcagag gagtcgtcaa atgagctcat
    16681 ctaaaacaat cggaattatc ggtggcggtc aactgggtca gatgatggcc atttctgcta
    16741 tctacatggg ccacaaggtt atcgcgctgg atcctgcggc ggattgcccg gtctctcgtg
    16801 tggcggaaat cattgtggca ccttataacg atgtagacgc cctccgtcag ttggcagacc
    16861 gttgcgatgt cctcacttac gagtttgaaa atgtcgacgc tgacggtttg gatgccgtta
    16921 tcaaggatgg acaactccct caagggacag acctgctccg catttcgcaa aatcgtattt
    16981 ttgaaaagga ctttttgtca aacaaggctc aagtcaccgt tgcaccttac aaggttgtga
    17041 cctcaagcca agatttggca gatatcgact tgtcgaaaaa ctatgttctc aagactgcga
    17101 ctggtggcta cgatggtcat ggacaaaagg ttattcgttc agaagcagac ttggaagcag
    17161 cctatgcgct agcagactca gcagactgcg tcttggaaga atttgtcaac tttgaccttg
    17221 agatttctgt catcgtgtca ggaaatggca aggaggtgac gtttttccca gttcaggaaa
    17281 atatccaccg caacaatatc ctgtctaaga ccattgtacc agcccgtatt tctgaaagtc
    17341 tagcagacaa ggctaaagct atggcagtgc gaatcgcaga acaactcaac ttgtctggaa
    17401 ctctctgtgt ggaaatgttt gcgacagctg atgacatcat tgtcaatgaa atcgccccac
    17461 gaccacataa ctctgggcac tattctattg aagcctgtga tttctctcag tttgacaccc
    17521 atattctggg tgttctcgga gcaccattac cagtcatcaa actccatgcg ccagccgtta
    17581 tgcttaatgt cctcggtcag catgtcgagg ctgctgaaaa atatgtcaca gaaaatccaa
    17641 gcgcccacct ccacatgtat ggtaaaatag aagcaaagca taatcgtaag atgggacatg
    17701 tgactttgtt tagtgatgtg ccggatagtg tggaagagtt tggggaaggg attgattttt
    17761 aggacaagtc tatgatacaa attatcgtta atacatttat tgaaaagtat aagactggag
    17821 cagttgttga agtgttgtat gccagtgctg accaagataa ggtacaagct aaatatgaag
    17881 aactagctgc acaatacccc gaaaattatt tagctatcta tgatgtaccg ctggatacgg
    17941 atttgaatac actagatcat tacccgtctg tgtttattga aaaagaggag tttgagtaga
    18001 aatcttggtt tacctagata gcttattccc aacagcttaa gaagaaagga aaaattaaca
    18061 catgatcaac cgttactctc gccctgagat ggcgaatatt tggagtgaag aaaataaata
    18121 ccgtgcttgg cttgaggtgg aaatcctctc tgacgaggca tgggctgagt tgggggaaat
    18181 ccctaaggaa gatgtggctt tgattcgcaa gaaggcggac tttgacatcg accgtatttt
    18241 ggaaattgag caggagacgc gccacgatgt ggtggctttc acgcgtgcgg tttctgagac
    18301 tcttggtgaa gagcgcaagt gggttcacta tgggttaact tctaccgacg tggtggatac
    18361 tgcttatggt tacctctaca agcaggccaa cgacatcatc cgtcgtgacc ttgaaaactt
    18421 cactaatatc atcgctgaca aggccaagga gcacaagttc accatcatga tggggcgtac
    18481 tcatggtgtg cacgctgagc cgacaacttt tggtcttaaa ttggcaactt ggtatagcga
    18541 aatgaaacgc aatatcgagc gtttcgagca tgcggctgct ggtgtagaag ctggtaagat
    18601 ttctggtgcg gttgggaact ttgccaatat cccaccattt gtagaggagt atgtctgcaa
    18661 caagcttggt atccgtgctc aagaaatctc tacacaagtc cttcctcgtg accttcacgc
    18721 tgagtacttt gcagttcttg ccagcattgc gacttcaatc gaacgtatgg cgactgagat
    18781 tcgtggtcta caaaaatctg agcaacgcga agtagaagag ttctttgcta aagggcaaaa
    18841 agggtcttca gcaatgcctc acaaacgcaa cccaatcggt tctgaaaata tgactggtct
    18901 ggcgcgtgtc attcgtggtc acatgattac ggcttatgaa aacgtcgctc tctggcacga
    18961 acgcgatatt tcccactcat cagctgagcg tatcatcaca ccagatacga ccattttgat
    19021 tgactacatg ctcaaccgtt ttggaaatat cgtcaagaac ttgacagtct tcccagaaaa
    19081 tatgatccga aacatgaact cgacttttgg tcttatcttt agccaacggg ctatgttgac
    19141 attgattgaa aaaggcatga cccgtgagca agcctatgac ttggtgcaac caaaaacagc
    19201 ctactcttgg gacaaccaag tagactttaa accacttctt gaggcagatt cagaagtaac
    19261 atcacgtctc actcaagaag aaatcgatga aatcttcaac ccagtttatt acaccaaacg
    19321 agtggatgat atctttgaac gtcttggact aggtgattaa ttaaaaaata aacagcgagc
    19381 ttcaatctcg ctgtttattt tttatcgaaa agacttagtc ttcttttctt ttagtgagtc
    19441 cataggctgc tagtgtggac atgagtcctg cgactactag ttctgcagaa tcgtgagttc
    19501 ctgtttcagg aagttttttc tctgttacca caggagctgg atcttgagga agagctttgc
    19561 tttcctcagc aggagcagtt gatggagctg gttggcttgg gatttctagt tttggttttt
    19621 cttcagcaat agcggcttgt ccgttttcat cgcctacatg tgttaccata gttccgactt
    19681 cgactatttg agtaacggct tcctgtgcta cgacactatt tacaagtgtt ttcacttcct
    19741 taccatcggc agaagtgctc acagagtaga agttgctacg atgtccattg acgcccttag
    19801 taatgacttg tgtttttcct ttgagtaaga gtggattttc acgagtcact gtggtaaatg
    19861 gaatttcttc ttcttggata tccagtctag gttttacctc agtagttggt gcaagaccac
    19921 tttcatcacc cttgtgagtt acaggagagc caacttcaac cacttggttt ataacttctt
    19981 tggttacctg gctatcaagg actgtttctg ttgtttttcc attttcagtg agtacagaga
    20041 tgtaatgagt tcgttcacct ttgactcctg ctgtgataat attttcctga ccagctggga
    20101 ggttaggatt ttctttcttg ataacttcaa atggaatttc ttcagttctt gtgatgagtt
    20161 ctggtctggt ttcaacattg gcagccactt cattttcatc taggcttcct gaatgagttg
    20221 cagctggttt gaggccttga agagcggctt ttaggttggc tacaagtgtg tcaagctcag
    20281 cttgtttatt acggttgagg ttgtaattta gagctgtttt agctgcgtca agggcctcaa
    20341 gactttcttt actatatcct tctaagtttg taggaatttt agctaattct tcgcggagag
    20401 cattataatt agcacggaag tagtctttgt tgtggtctgc aaaggcagtc atgagttcaa
    20461 agatttcctc ttccttgtac tcagcgcttg gtctatctgc ccagattgaa agcatacttc
    20521 cgactgttgg aagatctact tcaggatatt tggtagaagc tagttgattg aatggaactt
    20581 taccagaatt ttcaactgct tttgaaagag ggtaagcttc atcttgtttg tgattgccta
    20641 taacataata ccagtcaccg ttggtattca agaatttata gcctttgctt gctaggtatt
    20701 gaggtgatgc gaggttatat ccccaccagc ctttagacca gtaagaaatc aagacatctt
    20761 tgtcaaactg aacatcgtcc ttgtcttcat agtagaagcc atcgttgaag gccattggtt
    20821 gaagccctct ttctttggcc atagctgcga gggtgttggc atattcggca aatttgccat
    20881 agagttgata ccacttgagg tagtaccagc cttgggcact agtcgcatcg ttggcgtatt
    20941 cgtcagtacc aaagttgaaa atctttgttt tacctgcaaa gaagtccatg tatttaccga
    21001 tgagggcttt tacaaagttc atcgcttctt cgtttttcaa gtccatagtt gtttttgaaa
    21061 ctttatcaaa gtgggcttga ggatttttaa tacctaattt ttccatggca accagcatag
    21121 catccatgtg acctggactg ttaatagctg ggatgagacc aatgtcctta gatttagcgt
    21181 attcaattag ctctgtcact tctgcctgtg ttagtgcagt accgtttgga tcgtcgtagt
    21241 aagctttagt tccttcgata atagcttttt taacgtcatc actagcatag gtttttccgt
    21301 tggcagtaat ggtcatatca ttgagtagaa agcgaagtcc gtcatttcct agaaggagat
    21361 ggacatcaga atatccgagc tcactggcct tgtctacgat gcgtttgagc tggtccagag
    21421 taaagtattt gcgtccagca tcgattgaga ttaccttgtt tttggcaagt ttttcaacct
    21481 cacgtttagc ttcttcttct ttttgagctt caggcgtgag ggtcaagttg ttgacagttt
    21541 cttgaagttt agcaatggct tgatcaatcg tatcttgttg ggcacggcta aggttgctat
    21601 cgagagagcg aatagctttt tcagcttctt ttacggccgc gacgctttct gcagtataac
    21661 ggttcaggtc ttttggtacc tcgttaagtg cttgctctgc agattcataa tcagctgcga
    21721 agtattcagc gttggcattt gcaaaatgac gcatgagttt gaagaggtgt gatggtgaat
    21781 aacgtgcaga tggagtgtca gcccaagcag ctaccatacc accgatgatt gggatatcag
    21841 ctccttctgt ttttggtaca gaagtgattg gtgtgttttt aataccattg agcccctgat
    21901 cgagattgta ccagccttgg ccatcagcgt ttcgtccaag aacgtagtac caagcatcat
    21961 tggtattaag gatttggtga cctttttcag ctagtagttt agaagaagcg acatcgtagc
    22021 ctccccaacc accagtccac atagaaacga tgatgtcttt gtcaaaacta ccaaagcttg
    22081 tgtcgctatt gtagtagata ccgtcgttaa aggccattgg tttgagaccg tgcgatttta
    22141 caatacgagc gaggtcattg gcgtaggcaa taaatttttc atagcctttt acagggtagc
    22201 cttcgtttgg atagtattta tcagcttgaa gcacactcca acctttagca tctgtcgcat
    22261 cattggcata ttcatcaagt ccgatgttga agatttcagt ctttttcgcg aaataagcag
    22321 catacttgtc gataagggct tttgtaaaag cgacagcttg ttcgttgtca agatcgacag
    22381 tacgggctga tttcttccca aaatagctaa agttagggtt ttggattccc aattctttca
    22441 tggcattgag aatcgcatcc atgtgtccag gactatttac tgtcggaatg agaccgatac
    22501 ctttatcttt ggcatagtta atcagatctg tcatttgact ttctgttaag tgattgccgt
    22561 ttggatcgtt gtaataatca tttgtacctt tttcaatggc gcgtttgaca tcgtcactgg
    22621 cataggtctt gccgttagct gtgatgctca tatcgtccaa catgaaacgg agtccatcat
    22681 ttccgactaa taggtgtaaa tcagtgtagc cataatgttt cgctttatcg atgatttcct
    22741 tgagctgttc tggtgagaaa tatttacgtc cagcatcaat agaaacaatt ttctttttcg
    22801 ctagtttttc atttacagtt gcagcacgtt cctttcctgc ctctgttgcc ggtttgtcag
    22861 cctctgcttt cgcttcatct tttttagctg gtttatcctt gtcagtcttg tctgtatttg
    22921 actctttaga atcaacctct ttcgcttctt cctttttagg gctagcttct tctgcctttt
    22981 tattagcagt ttctttttca gcagaagttg gagttaccac ttctgcttta tcactaggag
    23041 ttgaactaac ttcctcttgt ggtttttctt ctgtttttgg aagactagct accttatcag
    23101 tagctggagt ttctgtttct acagtttttg gagcttctgg ttgaagcact gctttaggtg
    23161 tttcctcagt ccgattttcg gatgattgag gggaatcaga aaccgtatgg atggtcggtt
    23221 ggttttctgt agtagtagga gtaactccat cggctgcaac agtctgtgct tggaaggcaa
    23281 atccaattag aacagaagct gctcctacag cgtatttacg aatagaaaaa cgctgttgtt
    23341 tttcatgttt cattgcaaaa cctcctgatt gcattgttat attgatagcg attatataaa
    23401 tcaacgcctt tattttattt cttatattaa cgagagtcaa gaggagatga caaaaaacta
    23461 taataagtat aaaaaaatat aaaatttaaa cttaagattt cagattggtc ggaaaaaata
    23521 cgtatatata tctagtataa tttttggttc tatttctata aaatattcca caaattatag
    23581 aattttccaa aaataggtaa gcgctacctt tttggtgtag tataataagc atagaaaaag
    23641 cccaagcgat tagctcaggt tttcttctta gtgatcacgg tcacatgaga taaatttaat
    23701 cttgtagtaa tcagatcgtt tgtaagtttc actgtattct aaaacttggc cagttgattc
    23761 gagtttggtg attttagttt gtaggacagt agggaattgt tcatcgactc cgaggactga
    23821 agctgcatgt tctggagttg gaaagactat ttcgttgatt tcttcaaagt gttcatcatt
    23881 catgtgaatg tggtagtcta acttgaaacg attatagata gaactatagt attcaaggtt
    23941 tggataattt gcgttgatat attgttctgg gatgtaggat gtatggtaga tataaacgac
    24001 accgtttgat tcgcggatac gttcaatctt gtagtagaat tgatcgccgc gtagacccaa
    24061 tttttccaag taaacaagct tgtttccgcg ttcaattgaa agaacagtta ccttatcatc
    24121 tttagcattg aagagttcaa tatctgaaaa ctctacaagc ttgtgtttgc gtgcacgtga
    24181 aacgaaggtt ccttttcctt gttggcggac aatatagcca tctttggcaa ggtcgtttaa
    24241 ggcgcgaaca actgtgatag agctgacatc gtacattgaa atgagttctg cttcagtgta
    24301 aaatttatct ccactgctaa actgcccaga gatgatttta ttttttaatt cgtcttttat
    24361 gtattgatat ttgggaattg ccatattttt acctctattt tccttcttcc atagaaaatt
    24421 ttaccataaa agcgaaaaaa atagtagtct tttgaataaa aaattagaat aatagtttga
    24481 aaaattaagc gatataggga ttgctcatat tttataaatg tattctatac aaaattattt
    24541 taggtcctat attccgaatt taaagagcgt ttgaaatggg tctaaaaatg tttgaaacta
    24601 attgaatgtg tgtataatag taaaaatgca gtaaatatcc cgacaatttc tattgacaat
    24661 tcaaacagat tggtttataa ttaatataac aacaaatgaa agcgcaaact ttcgcggtcg
    24721 gaaggtagtt ttatgacacg atttgagata cgagatgatt tctatctcga tggaaaatca
    24781 tttaagattt tatctggtgc cattcattat tttagggttc ctccagagga ttggtatcat
    24841 tcgctctata acttgaaggc tcttggtttt aatacggtag agacttatgt tgcttggaat
    24901 ttacacgagc cttgtgaagg tgagtttcat tttgaaggtg atctggattt agagaaattt
    24961 ctccaaatag cgcaggattt gggtctctac gcaattgtgc gtccgtctcc atttatctgt
    25021 gcggaatggg aattcggtgg cttaccagct tggctcttga ccaagaacat gcgaattcgc
    25081 tcatccgacc cagcatatat cgaggcagtt ggtcgctact atgatcagtt attgccaaga
    25141 ctggtgcctc gtttgttgaa caatggtggc aatattctca tgatgcaggt tgaaaatgag
    25201 tatggttctt acggagaaga taaggcttac ctgagagcga ttcgacagct aatggaagag
    25261 tgtggcgtaa cctgtcccct ctttacatca gatggtccat ggcgagctac tctgaaagct
    25321 ggaaccttaa ttgaagagga cctctttgta acaggaaact ttggttctaa ggcaccttac
    25381 aacttttcgc agatgcagga attctttgat gaacatggta agaaatggcc actcatgtgt
    25441 atggagttct gggatggttg gttcaatcgc tggaaagaac cgattatcac acgggatcct
    25501 aaggaattgg cagatgcagt tcgagaggtt ttggaacaag gctctatcaa tctttacatg
    25561 ttccacggtg gtacaaactt tggtttcatg aatggttgct cagctcgagg aactttggac
    25621 ctgccacaag ttacatctta tgattacgat gcccttctgg atgaagaagg aaatccaact
    25681 gctaaatatc ttgcagtcaa gaagatgatg gcaacacatt tttcagagta tccgcagttg
    25741 gaaccactct acaaagagag tatggagttg gatgctattc cactagttga aaaagtttct
    25801 ttgtttgaaa ccttagatag cttgtcaagt cctgtagaaa gtctctatcc tcaaaagatg
    25861 gaggagctgg gacaaagtta tggctaccta ctttatcgaa cagaaacaaa ctgggatgca
    25921 gaagaagaaa gacttcgtat cattgatggt cgagataggg cccagctgta tgtcgatggt
    25981 cagtgggtta aaactcaata tcagacagag attggggaag atatttttta tcaaggtaaa
    26041 aagaaagggc tatctaggtt agatatcttg atagaaaata tggggcgtgt caactatggg
    26101 cataagttct tagcggatac gcaacgtaag ggaattcgga caggggtctg taaggatctg
    26161 catttcttac taaactggaa acactatcca ctcccactag acaatcctga gaaaattgat
    26221 ttttcaaaag gatggactca aggacaacca gccttttacg cttatgactt tacagtcgaa
    26281 gagccaaaag atacttacct agacttgtct gagtttggta agggagttgc ctttgtcaat
    26341 gggcagaatc taggacgttt ttggaacgtt ggcccaactc tctcacttta tatccctcat
    26401 agctatctca aggaaggtgc caaccgcatc attatctttg aaacagaagg tcaatataaa
    26461 gaagagattc atttaactcg taaacctaca ctaaaacata taaaggagga aaacttatga
    26521 caattgtagg atgccgtatt gatggacgtt tgatccacgg acaagtagcc aatctttggg
    26581 ctggaaaact aaatgtttca cgcattatgg ttgtagacga cgaagttgtc aacaacgata
    26641 ttgaaaagag tggtttgaaa cttgcgacac caccaggtgt gaaattgagt attttgccag
    26701 ttgagaaagc tgcagccaat attcttggtg gcaaatacga tagccaacgt ctctttatcg
    26761 tggctcgtaa accagaccgc ttccttggtt tggtagaagc aggtgtacca cttgaaaccc
    26821 ttaatgttgg gaatatgtct caaacaccag aaactcgttc tattacacgt tctatcaacg
    26881 tagtagacaa ggatgtggaa gacttccaca aactggcaga aaaaggtgtt aaacttactg
    26941 ctcagatggt tccaaatgat ccaatttcag actttttgag cttattaaaa taggaaaaaa
    27001 atttttagga ggtcattgtt atgatacaat ggtggcaaat tttacttctc actttgtact
    27061 cagcttatca aatctgtgat gagttgacga tcgtttcatc tgcaggttcc cctgtatttg
    27121 ctggtttcat tactggttta atcatgggag atgtgactac tggtttactt atcggtggta
    27181 acttgcaact gttcgttctt ggggttggta ccttcggtgg tgcttctcgt atcgacgcaa
    27241 cttctggtgc ggttcttgcg acagccttct ctgtttcaca aggaattgat gcaccgcttg
    27301 ccattactac aatcgctgta ccagtagcag ctctcttgac ttacttcgac gttcttggtc
    27361 gtatgactac taccttcttc gctcaccgtg tggatgctgc aatcgaacgc tttgactata
    27421 aaggtattga acgcaactac ttgcttggtg cgattccgtg ggctctatct cgtgcccttc
    27481 cagtcttctt tgcccttgct tttggtggtg cctttgtaca atcagtagta gacttcgttg
    27541 aagcctacaa atgggttgca gatggcttga cactcgcagg acgtatgctt ccaggtcttg
    27601 gatttgcaat cttgcttcgt taccttccag ttaaacgtaa ccttcactac cttgctatgg
    27661 gatttggttt gacagctatg ttgactgttc tttactcata tgtaacaggt cttggtggcg
    27721 ctgttgctgg tatcgtaggt actcttcctg ctgaagttgc tgaaaaaatt ggtttcgtga
    27781 acaacttcaa aggtttgtct atgattggta tttctatcgt aggtattttc cttgcagtgc
    27841 ttcacttcaa aaatagccaa aaagtagctg tagcagcacc ttctacacca tcagaaagtg
    27901 gggaaatcga agatgacgaa ttctaattac aaacttacaa aagaagattt taatcaaatc
    27961 aacaaacgta gcttgtttac tttccaatta ggttggaact acgaacgtat gcaagcttct
    28021 ggttaccttt acatgatctt gcctcagttg cgtaaaatgt atggtgatgg aactcctgaa
    28081 ttgaaagaaa tgatgaaagt tcatactcaa ttcttcaata cttcaccatt cttccatacc
    28141 attatcgctg gttttgacct tgccatggaa gaaaaagatg gtgtaggttc aaaagacgcc
    28201 gttaacggta tcaagacagg tttgatggga ccattcgctc ctcttgggga tacaatcttt
    28261 ggttcacttg tacctgctat catggggtca gtcgcagcaa ctatggctat cgctggccaa
    28321 ccttggggga tcttcctttg gattgcagtt gcagtagcgt atgacatctt ccgttggaaa
    28381 cagttggaat ttgcttacaa agaaggggtt aaccttatca acaacatgca aagtaccttg
    28441 acagctttga ttgacgctgc atccgtactt ggtgtcttca tgatgggtgc tcttgtagca
    28501 acagtgatta actttgaaat ttcttacaag ttgccaatcg gtgaaaagat gattgatttc
    28561 caagacatct tgaaccaaat cttcccacgt ttgcttccag caatctttac tgcctttatc
    28621 ttctggttgc ttggtaagaa aggtatgaac tctactaaag ctatcggtat tattatcgta
    28681 cttgctttgg ctctttctgc ccttggtcac tttgcacttg gaatgtaatt ccttatgact
    28741 aaatcattaa ttttggtgag ccatggtcgc ttctgtgagg agcttagagg tagcacagaa
    28801 atgattatgg gcccacaaga caacatttac acagtagctc ttcttccaga agatggccca
    28861 gaagaattta ctgctaagtt tgaagctgtt attgaaggat tggatgattt cctagtcttt
    28921 gcggatcttc tcggtgggac accttgtaat gtggtgagtc gcttgatcat ggaaggtcgt
    28981 gatattgacc tttacgcagg gatgaatctt ccaatggtga ttgaatttat caatgcgagc
    29041 cttacaggcg cagatgcgga ctacaagagc cgtgctgcag aaagcattgt gaaagttaat
    29101 gacctgttag cgggcttcga tgatgacgaa gatgaataat actcttcgaa aatctcttca
    29161 aactacgtca acgtcgcctt accgtaggta tatgttactg acttcgtcag tcttatccgg
    29221 caacctcaaa acggtgtttt gagctgactt cgtcagtctt atccggcaac ctcaaagcag
    29281 tgctttgagc agcctgcggc tagtttccta cagattttag ttggaactcg attcaattca
    29341 tgtgacaacg tgaaaatcgt tagagcattt tatatagaat atacatggga atggagctta
    29401 ctcccattcc tatatttaat agaaaaagag gaactcaatg ctacattata caaaagaaga
    29461 cttgctcgaa ttgggtgcag aaatcactac gcgtgaaatc taccaacagc ctgatgtatg
    29521 gagagaagct tttgaatttt atcaagcaaa acgtgaagaa attgcagcct tcctacaaga
    29581 aatcgctgat aaacatgact atattaaggt tatcttgaca ggtgctggga cttctgctta
    29641 tgtgggagac accttgctac cttactttaa ggaagtctat gacgaacgca aatggaattt
    29701 caatgctatt gcgacaacag atatcgttgc caatccagca acctatttga aaaaagatgt
    29761 ggcaactgtc cttgtgtctt ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt
    29821 tgatttggcc aaatccttgg tggatgagct ttatcaagtg acgattactt gtgcaacaga
    29881 tggtaaattg gctcttcaag ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc
    29941 tgtctctaat gatgctggat ttgccatgac ttctagcttt acgtctatga tgttgacagc
    30001 tctcttggtc tttgatccta cagaatttgc tgttaagtct gaacgttttg aagttgtatc
    30061 tagtcttgcc cgtaaagttt tagacaaggc agaagatgtc aaagagctcg ttgatttaga
    30121 ctttaaccgt gtcatctatc taggcgctgg tcctttcttt ggacttgctc atgaagctca
    30181 gctcaagatt ttggaattaa ctgctggtca agttgcgacc atgtatgaaa gcccagttgg
    30241 cttccgtcac ggtccaaaat ctcttatcaa cgacaataca gttgttttgg tctttggtac
    30301 aacgacagac tacactcgta agtacgactt ggacttggtt cgtgaagttg ctggtgacca
    30361 gattgctcgt cgtgttgtgc ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga
    30421 agtggccctt ggttgtggcg gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt
    30481 ttatgcccaa ctctttgccc tattgacttc acttaaggta gaaaataaac cagatacacc
    30541 gtctcctaca ggtacagtaa accgtgtagt acaaggtgtc ataattcacg aatatcaaaa
    30601 gtaagacagt gtttatgaat tcttgacaag aggatttgta aattatcaga taaaccatag
    30661 attgtcagta cgctttctat ggtttgtttg cttgagagaa atagtaaaag gagaacagaa
    30721 tgaaagcata cacagagcgt gtatttggaa atgttgaggg cgaggatgtc ttggcctatc
    30781 gatttgagac agacggtggc taccaacttg aggttatgac ttatggtgcg accatcttgc
    30841 gctatgtcgc acctgacaag gctggaaatt ttgccaatgt tatcttggga tttgatgact
    30901 ttgatagtta tgtaggcaat agtcccaagc atggagcaag tgtaggtcct gtagcgggtc
    30961 gtattgcagg tgcgaccttt gagctcaatg gtaagaccta tgaccttgag gttaataatg
    31021 ctagcaactg taatcacagt ggttcaactg gttgggattc cagcttgttt gaagttgaag
    31081 aagtaagcga tcatggcttg actctctaca cagagcgtac agatgggaca ggagggttcc
    31141 ctggaaatct caagatttgg atcagttatc acttggaaga aactggtgcc tatgaaatca
    31201 gctacaaggt gacgaccgat caggatacgc tggtcaatcc aaccaaccac agctatttca
    31261 acttgtctgg tgatttcacg cagacgattg accgtcatgt cttccaacta aacacagagg
    31321 gcatttactc aatcgctcct gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg
    31381 tggtcaaaca cgtctacaat ggtaccttgt tgaaggatat ctttgcagaa gaagatgagc
    31441 aaatccagct ggcatcaggt ttggatcatc catttgccct tcctgcaggc catgacaatg
    31501 ctggattcct ttatgaccaa aattcaggtc gcttcctgct tttcaagaca gaagctcctt
    31561 gctttgtggt ctacacagca aactttgtgg atgaaagtgt catcatagga ggtcagccaa
    31621 tgctacagca caatgggatt gctcttgaag cgcaagcttt accagatgcc attcacagtg
    31681 accttaaagg ccaagtcatt cttaaagctg gtcaaacctt caccagtaag acacgttatg
    31741 aacttgttgt gaaataaaaa agctggtcaa aaagtcttta aaattaaaat aacgcatatt
    31801 gtcaggtgat gaaaagtttg ataatatgcg ttttattatg aaatgattta ctttatatta
    31861 tcctgaaatg gtgttatttt tgagttatct ggcttgactt tcttgatgga aattatataa
    31921 tagttgtaat aataataatt acaacgagaa aagaggacca tttatgacct atgaatataa
    31981 gagtcacatt tatttggcag agacagcttt aaatgtaaag gatttggcca gtcaaacagc
    32041 cttttatcag caagttattg gtttagaaat cttatctcaa actgagacag agtccattct
    32101 aggccttggt ggaaaagtct tggtacagct gattcaagca caagagagcg gagaagtgag
    32161 ggaacattat ggtctttacc atttggccat tctcttgccc acacgcaagg ctttggctga
    32221 tgtcttgaaa cacctgacag atttgcaaat tcctcttgtc ggcggtgcag accatggtta
    32281 cagtgaagct atttacttgg aagatttgga gggaaatggc attgaactct atcgagataa
    32341 gccagtttcc acatgggata ttcgagaaga tggacgcatt atcggagtga cggaggctct
    32401 tgcggcgcag gacatttatg agttggggga aagagtagag ccctttatcc tggcagaagg
    32461 tacaagaatg gggcatattc atctttccgt caaggatagt cgaaagtcca gccagtttta
    32521 tcaaaaggtg ttagggctag agaataaatt cagtgtgcct ggcgctagtt ggattgcggc
    32581 tggagattac catcatcatt tagcagttaa cgaatggaga ggaaaaggtc tggcttcgcg
    32641 taagcaaggc ttaccaggtt tagcctacta tgtcatcgaa gtcgcacata aaaaagaact
    32701 gttaacgatt gcccaacgag cacaagaagt tgacgcacca atcaaatgga tgacatcgag
    32761 caaattggaa atcacagact cagatggcat cgtgacccgt attcgtttag caaggtaaaa
    32821 ttaggaattt ttaataagtt ataagtattg ctagtttgct ttttgaacgg tctttggtaa
    32881 cagaactgcg tgagctggat gggtgagaat tttgacaaag aagctgatta gagatataat
    32941 gaagaaaaat cgagcaagga aaaagaaatg acaaattcaa agtatattac ttgtttgaaa
    33001 cgttcagagg gccagttgcg tgggattcaa aagatgattg aaggagatcg tgactgtgct
    33061 gatattgtga cgcaactgac agcagtgaga tctagtgtag agcgcgtgat tgagatgata
    33121 attaccgaaa atcttactga atgtatcaat cagccactag atgattctga agctcaaaag
    33181 gaacgcctag aaaaggctat ccgatacttg attaaacgga aataaatgaa tgttttgaga
    33241 cgatatgtgc aaaggtctat taactattag aatagtttaa tgtgagtcaa aagaagttgt
    33301 aaaaaatctt taaaattaaa aaacgcatag tatcaggtat tgaaatgtac tgccccccaa
    33361 aagttagatt ctttctgtct aacttttggg gggcagtaca taaaaacctt gatagtatgc
    33421 gttttattgt ggggagactt atactcttcg aaaatctctt caaaccacgt cagtttcacc
    33481 ttgccgtaga tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
    33541 gagctgactt tgtcagttcc atccacaacc ttaaaacagt gttttgagca gcctgcggct
    33601 aacttcctag tttgcacttt aattttcatt gagtattact tcatcttctc atgaaattga
    33661 gtttttgccc agctcctctt gattattcta cttgaccggg ccaagtattc ataccacctt
    33721 ctacgttggt aacggtgagg ccttgggagc tgagaaattg gcaggtagat gcagagcgga
    33781 ctcctccttg acaaataaca tagtattcat ggtcaggttt gagttctttg tagccttgct
    33841 ctaaggtact taatggaaga tttttggcac ctggtgcatg tcctgcttgg aattcatgtg
    33901 cttcacggac atcgataagt tctagatttt cattttagta ttttccataa aagtcagcca
    33961 tgctgatact agtttccata ttctactcct tctgggttag ccattttgta tagtgaataa
    34021 gcgccgtcaa ggttttggac ggtaaatcct gcttgcttga ggataggctc tgcgatatag
    34081 ctgcgcaaac cactgtggca gctgacgatg taggcttgtt ttttgtccag ttcatcagct
    34141 tcctccttga cactttgtca gtttttgata caatagtaca aaattagagg aggtgggcta
    34201 tgattcagaa acatgcgatt cccattttag agtttgatga taatcctcag gcggttatca
    34261 tgcccaatca cgaggggttg gatttgcagt tgccaaagaa gtgtgtctat gcttttttag
    34321 gtgaggagat tgaccgctat gcgagggaag taggggcgaa ctgtgttggc gaattcgttt
    34381 ctgctaccaa gacctatcca gtctatgtca tcaactacaa gggtgaggag gtctgtctgg
    34441 ctcaggctcc tgttggctcc gctccagcag cccagtttat ggattggttg attggctatg
    34501 gtgtggagca gattatctct actgggacct gtggtgtcct agctgatata gaggaaaatg
    34561 cctttctagt ccctgttcgc gctttgcgag atgagggagc cagttaccac tatgtggcac
    34621 cttgtcgtta tatggaaatg cagccagagg ctattgctgc tattgaggaa gttttggaag
    34681 acagagggat tccttatgaa gaagtcatga cctggacgac agacggtttt taccgagaaa
    34741 cggctgaaaa ggtggcttat cgtaaggaag aaggctgtgc tgttgtggag atggagtgtt
    34801 ctgctcttgc ggcagtagct caattgcgtg gggttctctg gggtgaattg ttgttcacag
    34861 cagattctct agcggacttg gaccagtacg acagtcgtga ctggggctcg gaagctttta
    34921 ataaggcgct agaactgagt ttagcaagtg ttcaccacct ttagttgtac tggcaaagga
    34981 tttgttttat cataaaatgt ctagctcata cttttcaaaa atatgtttaa acgaggtcac
    35041 cttcctcttg tcctaggcat gttgaggttg ggaaaaatct ttaaaatcag aaaaacgtat
    35101 catatcaggt gataaaaact ttgatactat gcgttttatg ttggtaagat ttagagtgag
    35161 atgaaatgat actcttcgaa aatctcttca aaccgcgtca acgtcgcctt gccgtataga
    35221 tgttactgac ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttgag ctgacttcgt
    35281 cagttctatc cacaacctca aaacagtgtt ttgagcaacc tgtgactagc tttctaagcg
    35341 atgccttggt tctcattgcc tataatcaaa aagagaaatt ttctcctgaa aagcatatag
    35401 agtagctggc gttaaaagct cctgtcttgc ttttttgacc tatagtcaca tctatcaagt
    35461 attgttcttg cctaagctat caataaaaag gtggcatttt ttaggcttgg tgttagtgaa
    35521 ttttgcctta tcctatctaa gtcatttcga gctttttatg gtacaatgga aacatgttat
    35581 tcaaattatc taaggaaaaa atagagctag gcttatctcg tttatcgcca gcccgtcgta
    35641 tttttttgag ttttgccttg gtcattttac taggctctct tcttttgagc ttgccctttg
    35701 tccaagttga aagctcacga gcgacttatt ttgatcatct tttcactgct gtctctgcag
    35761 tctgtgtgac aggtctctca acccttccag tagctcacac ctataatata tggggccaaa
    35821 taatctgttt gctcttgatt cagatcggtg gtctagggct catgaccttt attggggttt
    35881 tctatatcca gagcaagcaa aagcttagtc ttcgtagccg tgcaactatt caggatagtt
    35941 ttagttatgg agaaactcga tctttgagaa agtttgtcta ttctattttt ctcacgacct
    36001 ttttggttga gagcttggga gctattttgc ttagttttcg ccttattcct caacttggct
    36061 ggggacgtgg tctttttagt tccatttttc tagcgatctc agccttctgt aatgccggtt
    36121 ttgataattt agggagcacc agtttatttg cttttcagac cgatttactg gtcaatctgg
    36181 tgattgcagg cttgattatt acaggcggcc ttggttttat ggtctggttt gatttggctg
    36241 gtcatgtagg aagaaagaaa aaaggacgtc tgcactttca tacgaagctt gtattattat
    36301 tgactatagg tttgttgtta tttggaacgg caactactct ctttcttgag tggaacaatg
    36361 ctggaacgat tggcaatctc cctgttgccg ataaggtttt agttagcttt tttcaaacag
    36421 tgacgatgcg aacagctggc ttttctacga tagattatac tcaggctcat cctgtgactc
    36481 ttttgattta tatcttacag atgtttctag gtggggcacc tggaggaaca gctgggggac
    36541 tcaagattac gacatttttt gtcctcttgg tctttgcacg aagtgagctt ctaggcttgc
    36601 ctcatgccaa tgttgcgaga cgaacgattg cgccgcgaac ggttcaaaaa tcctttagtg
    36661 tctttattat ctttttgatg agcttcttga taggattgat tctgctaggg ataacagcca
    36721 aaggcaatcc tccctttatc cacctcatat ttgaaaccat ttcagctctt agtacagttg
    36781 gtgtaacggc aaatctgact cctgaccttg ggaaattggc tctcagtgtt atcatgccac
    36841 ttatgtttat gggacgaatt ggtcccttga ccttgtttgt tagcttggca gattaccatc
    36901 cagaaaagaa agatatgatt cactatatga aagcagatat tagtattggt taagaaagga
    36961 aagagcatgt cagatcgtac gattggaatt ttgggcttgg gaatttttgg gagcagtgtc
    37021 ctagctgccc tagccaagca ggatatgaat attatcgcta ttgatgacca cgcagagcgc
    37081 atcaatcagt ttgagccagt tttggcgcgt ggagtgattg gtgacatcac agatgaagaa
    37141 ttattgagat cagcagggat tgatacctgc gataccgttg tagtcgcgac aggtgaaaat
    37201 ctggagtcga gtgtgcttgc ggttatgcac tgtaagagtt tgggggtacc gactgttatt
    37261 gctaaggtca aaagtcagac cgctaagaaa gtgctagaaa agattggagc tgactcggtt
    37321 atctcgccag agtatgaaat ggggcagtct ctagcacaga ccattctttt ccataatagt
    37381 gttgatgtct ttcagttgga taaaaatgtg tctatcgtgg agatgaaaat tcctcagtct
    37441 tgggcaggtc aaagtctgag taaattagac ctccgtggca aatacaatct gaatattttg
    37501 ggtttccgag agcaggaaaa ttccccattg gatgttgaat ttggaccaga tgacctcttg
    37561 aaagcagata cctatatttt ggcagtcatc aacaaccagt atttggatac cctagtagca
    37621 ttgaattcgt aaagagggat gacccctctt ttttgatgct taagatggca aatagagaca
    37681 gaagcccctt gtcttctagt aaaagttctt caaaggctgg actttatggt aaaatagaag
    37741 gaagtgacaa gagagagtaa tactcaatga aaatcaaaga tcaaactagg aaactagctg
    37801 cgggctgctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac
    37861 actgttttga ggttgcagat agaactgacg aagtcagtaa catctatacg gcaaggcgac
    37921 gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc cctaaaggag
    37981 cagattatga agttattgtc tatcgccatt tctagctata atgcagcagc ctatcttcat
    38041 tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat tatcaatgac
    38101 gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta tcctaatatc
    38161 gttagagcca tctatcagga aaataaaggc catggcggtg cggtcaatcg tggcttggca
    38221 gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga tcctcgtgcc
    38281 tacttgaaaa ttcttgaaac cttgcaggaa tttgagagca agggtcaaga ggtggatgtc
    38341 tttgtgacca attttgtcta tgaaaaggaa ggtcagtctt gtaagaagag tatgagttac
    38401 gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa tttctccaaa
    38461 ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg tgctagccag
    38521 ttctaattgc ctgaacatac tttttatgtc gataatctct ttgtctttac gccccttcag
    38581 caggtcaaga ccatgtacta tctgcctgtc gatttctatc gttatttgat tgggcgtgag
    38641 gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact caaggtcaat
    38701 cgactcttgg tagaccaact ttatttgtcc caagtgagtc atcccaaaat gcgagaatat
    38761 ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa ccgatctgga
    38821 acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca gaaaaatcca
    38881 gaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg
    38941 ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta tggatttaat
    39001 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
    39061 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
    39121 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
    39181 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
    39241 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
    39301 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
    39361 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
    39421 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aagaaaatcc
    39481 agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
    39541 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
    39601 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
    39661 tggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
    39721 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
    39781 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
    39841 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
    39901 aacttataaa tctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
    39961 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
    40021 cgaaaaagct gttaaagata acgttaaaga cagtatcgat gttccagcag cctacctaga
    40081 aaa
//
LOCUS       DAVMBH010000014        40056 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVMBH010000014 DAVMBH010000000
VERSION     DAVMBH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.014"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..269
                     /locus_tag="VYP30_000855"
     CDS             <1..269
                     /locus_tag="VYP30_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807883.1"
                     /translation="SSFHFLSPKLENEKNDNFREIAESRVSKVFGTMNSIANTAYKPN
                     YDYTNQQVEEIFEGYKNKIVEIKGIYSPLEKFLFSTQSKIIIEK"
     gene            276..554
                     /locus_tag="VYP30_000856"
     CDS             276..554
                     /locus_tag="VYP30_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807884.1"
                     /translation="MEFWNDTIQTVKEWRPVNYSVAEDEDFEAVKKKAIRNFQDYLKL
                     LDENTEEGYQEVIRLFTFSKFYGEELCNDEELNKLSRDIRGRLKKFRS"
     gene            816..2093
                     /locus_tag="VYP30_000857"
     CDS             816..2093
                     /locus_tag="VYP30_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1807885.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETMIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2169..3653
                     /locus_tag="VYP30_000858"
     CDS             2169..3653
                     /locus_tag="VYP30_000858"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1807886.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     NKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNALNSQGQYELTNFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAIASAVYRKYQATTGDATKTVIASTASPYKFPVVAVEALTGKVGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTIVAAADMQVAVEAYLGL"
     gene            3714..4994
                     /locus_tag="VYP30_000859"
     CDS             3714..4994
                     /locus_tag="VYP30_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1807887.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALSAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMNLKG"
     gene            4998..5618
                     /locus_tag="VYP30_000860"
     CDS             4998..5618
                     /locus_tag="VYP30_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1807888.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFALFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5784..6926
                     /locus_tag="VYP30_000861"
     CDS             5784..6926
                     /locus_tag="VYP30_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1807889.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7332..7670
                     /locus_tag="VYP30_000862"
     CDS             7332..7670
                     /locus_tag="VYP30_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1807890.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7681..8039
                     /locus_tag="VYP30_000863"
                     /pseudo
     CDS             7681..8039
                     /locus_tag="VYP30_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8146..8763
                     /gene="pcp"
                     /locus_tag="VYP30_000864"
                     /pseudo
     CDS             8146..8763
                     /gene="pcp"
                     /locus_tag="VYP30_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8791..9648)
                     /locus_tag="VYP30_000865"
     CDS             complement(8791..9648)
                     /locus_tag="VYP30_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1807891.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9778..10920
                     /gene="tgt"
                     /locus_tag="VYP30_000866"
     CDS             9778..10920
                     /gene="tgt"
                     /locus_tag="VYP30_000866"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1807892.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11018..12835
                     /locus_tag="VYP30_000867"
     CDS             11018..12835
                     /locus_tag="VYP30_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1807893.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQESKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12988..14139
                     /gene="nagA"
                     /locus_tag="VYP30_000868"
     CDS             12988..14139
                     /gene="nagA"
                     /locus_tag="VYP30_000868"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1807894.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14302..15360
                     /locus_tag="VYP30_000869"
     CDS             14302..15360
                     /locus_tag="VYP30_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1807895.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15511..15876
                     /locus_tag="VYP30_000870"
     CDS             15511..15876
                     /locus_tag="VYP30_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1807896.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15952..16893
                     /locus_tag="VYP30_000871"
     CDS             15952..16893
                     /locus_tag="VYP30_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1807897.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDHKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16841..17857
                     /locus_tag="VYP30_000872"
     CDS             16841..17857
                     /locus_tag="VYP30_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1807898.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            17859..18185
                     /gene="comGC"
                     /locus_tag="VYP30_000873"
     CDS             17859..18185
                     /gene="comGC"
                     /locus_tag="VYP30_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1807899.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYHDKNGGA
                     NRKVND"
     gene            18154..18582
                     /locus_tag="VYP30_000874"
     CDS             18154..18582
                     /locus_tag="VYP30_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1807900.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFSAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18587..18847
                     /locus_tag="VYP30_000875"
     CDS             18587..18847
                     /locus_tag="VYP30_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807901.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            18810..19271
                     /locus_tag="VYP30_000876"
     CDS             18810..19271
                     /locus_tag="VYP30_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1807902.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS"
     gene            19249..19662
                     /locus_tag="VYP30_000877"
     CDS             19249..19662
                     /locus_tag="VYP30_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1807903.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            19799..20393
                     /locus_tag="VYP30_000878"
                     /pseudo
     CDS             19799..20393
                     /locus_tag="VYP30_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20454..21407
                     /locus_tag="VYP30_000879"
     CDS             20454..21407
                     /locus_tag="VYP30_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1807904.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21458..22648
                     /locus_tag="VYP30_000880"
     CDS             21458..22648
                     /locus_tag="VYP30_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1807905.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            22797..23168
                     /gene="rnpA"
                     /locus_tag="VYP30_000881"
     CDS             22797..23168
                     /gene="rnpA"
                     /locus_tag="VYP30_000881"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1807906.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23143..23967
                     /locus_tag="VYP30_000882"
     CDS             23143..23967
                     /locus_tag="VYP30_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1807907.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            23986..24972
                     /locus_tag="VYP30_000883"
     CDS             23986..24972
                     /locus_tag="VYP30_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1807908.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25023..25646
                     /locus_tag="VYP30_000884"
     CDS             25023..25646
                     /locus_tag="VYP30_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1807909.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            25777..27234
                     /locus_tag="VYP30_000885"
     CDS             25777..27234
                     /locus_tag="VYP30_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1807910.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSFMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIIIGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27257..27538
                     /locus_tag="VYP30_000886"
                     /pseudo
     CDS             27257..27538
                     /locus_tag="VYP30_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
     gene            27615..28100
                     /locus_tag="VYP30_000887"
     CDS             27615..28100
                     /locus_tag="VYP30_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1807911.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28117..28782
                     /locus_tag="VYP30_000888"
     CDS             28117..28782
                     /locus_tag="VYP30_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1807912.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            28786..29649
                     /locus_tag="VYP30_000889"
     CDS             28786..29649
                     /locus_tag="VYP30_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1807913.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKSCDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29651..30355
                     /locus_tag="VYP30_000890"
     CDS             29651..30355
                     /locus_tag="VYP30_000890"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1807914.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30534..32207
                     /locus_tag="VYP30_000891"
     CDS             30534..32207
                     /locus_tag="VYP30_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1807915.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32319..33410
                     /gene="ulaG"
                     /locus_tag="VYP30_000892"
     CDS             32319..33410
                     /gene="ulaG"
                     /locus_tag="VYP30_000892"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1807916.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33524..35500
                     /gene="tkt"
                     /locus_tag="VYP30_000893"
     CDS             33524..35500
                     /gene="tkt"
                     /locus_tag="VYP30_000893"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1807917.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            35617..35916
                     /gene="yajC"
                     /locus_tag="VYP30_000894"
     CDS             35617..35916
                     /gene="yajC"
                     /locus_tag="VYP30_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1807918.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            35963..36391
                     /locus_tag="VYP30_000895"
     CDS             35963..36391
                     /locus_tag="VYP30_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1807919.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36393..36803
                     /locus_tag="VYP30_000896"
     CDS             36393..36803
                     /locus_tag="VYP30_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807920.1"
                     /translation="MENLTNFYEKYRVYLTRPRLEILAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37103..39754
                     /gene="adhE"
                     /locus_tag="VYP30_000897"
                     /gene_synonym="adhC"
     CDS             37103..39754
                     /gene="adhE"
                     /locus_tag="VYP30_000897"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1807921.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELSFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12279 a         7084 c         8957 g        11736 t
ORIGIN      
        1 catcctcatt tcatttttta tctccaaaat tggagaatga aaaaaacgat aattttagag
       61 aaattgctga atcaagagtt agtaaagtat ttgggacaat gaactcaata gcaaatactg
      121 cttataaacc taattatgat tatactaatc agcaggtgga agagatattt gaaggatata
      181 agaataaaat agtggagata aaaggtatct atagtccgtt ggaaaaattc ttgttttcaa
      241 cccagagtaa aataataatt gaaaagtgag ataaaatgga attttggaat gacacaattc
      301 aaaccgtcaa agagtggcga ccagtcaatt attcagttgc tgaagatgaa gactttgaag
      361 ctgtgaagaa aaaagcaatt agaaattttc aagattatct aaaattactt gatgagaata
      421 ctgaagaagg ctaccaagaa gttataaggt tatttacatt tagcaaattc tatggtgaag
      481 aactgtgtaa cgatgaagaa ctgaacaaat tgagtagaga tataagagga agattaaaaa
      541 aattccgttc ctaaaaagtt actaaaaatc aaaattttat tttttcaaac aatataaatg
      601 gttttttata atgttgatta tgctgattta taaagatata aaatcttaaa cactaaactc
      661 aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat agtatagtgt
      721 taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat tatagttatt
      781 caaattttat ttagattgag aaagtgtagg gtagtatgtc ttgttctatc gatttattaa
      841 aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga attgagttgg
      901 agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata aaggatctat
      961 ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat tttggcaatc
     1021 tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt tcctatacaa
     1081 cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat cgtttcaata
     1141 attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt gttggctgtg
     1201 gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca cgctatcaga
     1261 tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta catcatttcc
     1321 ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca aaaaccaact
     1381 acttgcgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat ttatttgcaa
     1441 actctgagtt ttcgggtgcg gattgggata cgaaaatttc aagggatatt ttctgggaag
     1501 aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc cttaatgatg
     1561 aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa cgtgatgggc
     1621 agacctatta tttttatcct attcaggctg gggactattt ggctacgcct gaaatccaag
     1681 catttgctct gaatggggat gaggttatta tttaccccca agagaaggat tttgaaactc
     1741 atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt cgtagtgtgt
     1801 gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga ttattggtta
     1861 atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta tttggttatg
     1921 attacaagtt tttaaggaga caattttcta agaaaaatct tacagatgag gaagaaacta
     1981 tgattattga attttccaaa gacttactcc tactagctga ggagggacta gtggtgagaa
     2041 ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta taatttctct
     2101 tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata gataaaggat
     2161 agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca gtaactgcca
     2221 gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg gttacttatc
     2281 caaaggtaga tttgaacttt aacaaattga aagatgcttc ttaccaggaa gttgctaagc
     2341 tagttttgtc agcattttta gatgacttta cagctgagga gttggactac tgtatcaaca
     2401 atgcctacga tagcaaattt gatactccag ctattgcacc attagtgaaa ttagatgggc
     2461 aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg gccttgtcta
     2521 ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac aagattgtta
     2581 tcttgacagc gacatctggt gacacgggga aagctgctat ggcggggttt gcggatgtgc
     2641 ctggtactga gattatcgtc ttttatccaa aggatggtgt cagcaagatt caagagttac
     2701 aaatgaccac tcaaactggc gacaatactc atgttattgc tattgatggt aactttgacg
     2761 atgcgcaaac aaatgtgaag cacatgttta acgacgtggc tcttcgtgaa aaattgacta
     2821 ccaacaagtt gcaattttca tcagctaact ctatgaacat tggtcgtctg gtgccacaaa
     2881 ttgtttatta tgtttatgct tacgctcaat tggtcaagac tggtgagatc gtggctggtg
     2941 ataagattaa cttcacagta ccaacaggaa actttggaaa tatcttggct gccttttatg
     3001 ccaaacaaat cggtctccca gttggtaaat tgatctgtgc ttcaaatgac aacaatgttt
     3061 tgacagactt cttcaagaca cgtgtctatg acaagaaacg tgagtttaag gtaacaacca
     3121 gcccatctat ggatatcttg gtatcttcaa acttggagcg tttgattttc catcttttgg
     3181 ggaatgatgc ggttaagacg gctgaactca tgaatgcttt gaatagccaa ggtcaatatg
     3241 agttgactaa ttttgatgca gagattttgg acctctttgc agctgaatat gcgactgagg
     3301 aagaaactgc ggcagaaatc aagcgtgttt atgagtcaga ttcttatatc gaggatcctc
     3361 atacagcgat tgcctcagca gtgtatagaa aataccaggc gactactgga gatgcgacta
     3421 agacagtgat tgcttcaaca gctagtccct acaagttccc agtagttgca gtagaagcgc
     3481 taacagggaa agttggcttg actgattttg aagctttggc tcaattacat gaaatctcag
     3541 gcgttgcagt gccaccagca gttgatgggc ttgagacagc tcctgttcgt cacaagacaa
     3601 tagtggcagc tgctgacatg caagtagcgg ttgaggctta tttaggactt taagatagag
     3661 ggagtaaact cggttgggaa accaactgag tttcttttca tcaggaggag agattgttta
     3721 agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac tttttgcaga
     3781 tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata gctatttcag
     3841 gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc gctctgggag
     3901 ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg aagttggcct
     3961 atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta ggatttttgt
     4021 ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat gtagctgaga
     4081 gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt ttaatgacta
     4141 gtctgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat gttagttttt
     4201 tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg gatatgggga
     4261 tagctggtgt tgcttggggg acaattctgt ctcgtttggt tggtcttgtg attttgtggt
     4321 cacaattaaa actgccttat gggaagccaa cttttggttt agataaggaa ctgttgacct
     4381 tggctttatc agcagctgga gagcgactta tgatgagggc tggagatgta gtgatcattg
     4441 ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga gaagtcttga
     4501 cccagtttaa ctatatgcct gcctttggcg tcgctacggc aacggtcatg ctgttggccc
     4561 gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa accttttggc
     4621 tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt gtaccattaa
     4681 ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg acactgtttt
     4741 cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc tggcagggat
     4801 taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt atccgcattg
     4861 ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt tgggcagggt
     4921 ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag cgctatatga
     4981 acttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac gggactttat
     5041 tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctctg ttttctattc
     5101 cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa gatttgcttg
     5161 tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg cgtgcccaga
     5221 gtctggctga gaaaaatgct caggtagttt tgatgccagg tgcgcgtgag gtgctagctt
     5281 gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac aacgctttta
     5341 ccattctcaa ggacttgggg gtggaatcct attttacaga gattttaacc agtcagagtg
     5401 gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag tatcagttga
     5461 attctgataa tacttattat ataggggatc ggactctgga tgtggaattt gcccagaata
     5521 gtgggattca aagcatcaac tttttagagt ctacttatga agggaatcac aggattcaag
     5581 cgttagcaga tatttcccgt atttttgaga ctaagtgata aaaagattgt gtcagttttg
     5641 tgacagagac ctaacaaact atttcaagta acctagtttg ttacaaggaa tagacagttc
     5701 tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatgat agacaggtac
     5761 tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca acagtagcct
     5821 tgtcatttgc cccagtattg gcaactcaag cagaagaagt tctttggact gcacgtagtg
     5881 ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa aacaagttat accgtacagt
     5941 atggtgatac tttgagcacc attgcagaag ccttgggtgt agatgtcaca gtgcttgcga
     6001 atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg acaacgactg
     6061 tcaatgaagc agaagaagta acagaagttg aaatccaaac acctcaagca gactctagtg
     6121 aagaagtgac aactgcgaca gcagatttga ccactaatca agtgaccgtt gatgatcaaa
     6181 ctgttcaggt tgcagacctt tctcaaccaa ttgcagaagc tccaaaagaa gtagcatcaa
     6241 gttcagaagt tacaaagaca gtgattgctt ctgaagaagt ggcaccatct acgggcactt
     6301 ctgtcccaga ggagcaaacg gccgaaacaa gcagtgcagt tgcagaagaa gctcctcagg
     6361 aaacgactcc aggtgagaag caggaaacac aagcaagccc tcaagcagca tcagcagtgg
     6421 aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag
     6481 cagtttctac ttatcaacca gaagagacga aaataatttc aacaacttac gaggctccag
     6541 ctgcgcccga ttatgctgga cttgcagtag caaaatctga aaatgcaggt cttcaaccac
     6601 aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt
     6661 atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgatttt atggtaccag
     6721 aaagttcaga attaggggat aagattgcgg aatatgctat tcaaaacatg gccagccgtg
     6781 gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc
     6841 cagctaacac ttggaatcca atgccagacc gtggtagtgt gacagaaaat cactatgacc
     6901 acgttcacgt ttcaatgaat ggataaaccc gacttggtaa catcattttg acgaatgaga
     6961 tctagctttc gtgataggaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa
     7021 atctcttcaa accacgtcag ttttatctga aacctcaaag ctgtgctttg agcaacctgc
     7081 gactagcttt ctagtttact ctttgatttt cattgagtat caatttgaat ggaaaatgga
     7141 aagttattat cttgtaataa tccaagcaac attcttgcaa tctattttac tttatatcac
     7201 aattgattgg tcaactattg ataagtcaat ggataggagg aagaaatgat agagattcaa
     7261 gatttactgt atcaactccg cttgtctgag caagcgagta cgcaattgtt tgaaaaaggc
     7321 ttgggattag tttgacacgg tatcagattt tactgttttt gctggagcat tctccttgta
     7381 accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc tgctttgaca cggcatttca
     7441 agattttgga aacggaaggt ttggtggagc gtcatcgtaa tcctgaaaat cagcgggaag
     7501 tgttggtaga ggctgcgaag tatgccaagg agcagttagt ggtgaatccc cctctgcaac
     7561 atatcaaggt taaggaagag atggaaagta tcttaacaga gtttgagaga acagaactca
     7621 gccgtttatt aaataaattg gttttgggta ttgaaaatat agaaatttaa ggagaaatag
     7681 atgtcaatta ttttaacaac gatcgttgct ttggagcatt tttacatttt ttatttggaa
     7741 agtattgcca cgcaatcaga tgcgactagt cgtgtattta atatggaaaa ggaagaattg
     7801 gctcatccgt cagtaagttc attgttcaaa aatcaaggaa tttataaggc tctgctagga
     7861 gtctttctct tgtatgtcat ttatttctca cagaatttag aaattgtgac tatttttgtc
     7921 ttatttgtga ttggtgctgc gacttacggc tctttaacag cggataaaaa attattttga
     7981 agcaaggtgg atcagctatt ttggccttga ttagtatttt actctttaaa tacacttgaa
     8041 ggttgattct aatctcgcta atccttttta atccagaata agggaaatat gttatacttg
     8101 tttttaagaa aaaagtctca ttgaattggt tttgaggagt tagaaatgaa agtattagtg
     8161 acaggttttg agcccttttg aggccattaa aggtttacca gctgaaatcc atggtgctga
     8221 ggtccgttag ctagaggtgc cgacagtttt tcacaaatct gctcaagtat tggaagaaga
     8281 gatgaatcgt tatcaacctg actttgtcct ttgtattggg caagctggtg gaagaactag
     8341 tttgacacct gaacgagtgg ccattaatca agacgatgca cgcatttctg ataacgaaga
     8401 taatcaaccg attgaccgtc ccattcgccc agatggtgct tcggcctact ttagtagttt
     8461 gccgattaaa gcgatggttc aagctataaa aaagagggct taccggcctc tgtttccaat
     8521 acggcaggga cttttgtctg cagccatttg atgtatcagg ctctctattt ggtagaaaag
     8581 aaatttccat atgttaaggc aggttttatg catattcctt atatgatgga acaggtggtg
     8641 aacagacaga ctattccagc tatgagttta gtggatattc ggcgagggat agaagcagca
     8701 atcggcgcta tgatagaaca tggagatcag gaactcaagt tggtaggcgg agaaactcat
     8761 tgatagaaaa aagcttgagg ggaaaaacct tcaagctttt ggacgttttc gagccaatac
     8821 tgctcggtaa aacataattt tagtgcattg gatataaggt aggagtgaaa aactagcaat
     8881 gccaaaggta atccaattga ggaagtacca aggaagaagc tgtaaatcta ggacaaagcg
     8941 ctggaacttg tagcccttca taaaggaacg gctagttttt aggattcgtc ttggtgggac
     9001 ctgtcctagg tctagactat aacagagaag aaattccacc tgtgaatagg cataatactg
     9061 tggaatatag aggatatttc ctacaatgat caagatgaga cttgcaagaa agtagagtcc
     9121 aaagaccatg aggaaacgct cggtttcaac tgatgagaga tctagatttg gaaactcagg
     9181 atgtagggtg acgaattttt tggctaaaaa gctactataa aagaggaggt aaatcccaag
     9241 taaattaggg atactccata aaaagagata gaaacgtttg agaagtaggg tcaaaaaggt
     9301 ttgagaaaag cgctcctcat caaagagagc taggctgttt tttacagatg gctccgtttt
     9361 agaatctttc atgagtgtca gtgttgcata gacggaactg gtcaaaagaa tagtcccgat
     9421 aaaggagact agtagaggaa agaggtaggc ttgaagtatt tggccaagta tgctgaaaaa
     9481 tggctgttct aaaacagtcc cgtggatccg agataaggga ttaagaaaac tagataagat
     9541 gaccagcata ctgggaagga tatagaggag aaagagacgg ggggtgtcag cctgaaaatg
     9601 ttttgactcc tgacgaattg tttttaaatc aatttttgga tagttcattc tcttattata
     9661 ccatagttct tatacatagt tcgtgacagt tcctactttt tttgataaaa tcatacagtg
     9721 tgtccttggg cacactgtat gaactgggac tgtctttccc agcttcggag gtaaaaaatg
     9781 tcagattcac caatcaaata tcgtttgatt aagaaagaaa aacacacagg agctcgtctg
     9841 ggagaaatca tcactcccca cggtaccttt ccgacaccta tgtttatgcc agttgggaca
     9901 caagccactg tcaaaactca gtcacctgaa gaattgaagg agatgggttc gggaattatc
     9961 ctatcaaaca cctatcatct ctggcttcgc cctggagatg aactcattgc acgcgctggt
    10021 ggtctccaca agttcatgaa ttgggaccag cctatcttga cagatagtgg tggttttcag
    10081 gtttattctt tagcagatag ccgtaatatc acagaagaag gagtaacctt taaaaatcat
    10141 ctaaatggtt ctaagatgtt cctatcccca gaaaaagcca tctctattca gaataatctg
    10201 ggttcagaca tcatgatgtc ctttgatgaa tgtcctcagt tttatcaacc ttatgactac
    10261 gttaagaaat cgatcgagcg taccagccgt tgggctgagc gtggtttgaa ggctcaccgt
    10321 cgtccacatg accaaggttt gtttggaatt gtgcaaggtg caggatttga agaccttcgc
    10381 cgccaatcag ctcatgatct tgtcagcatg gatttctcag gctactctat cggtggtttg
    10441 gcagtgggag aaacccatga agagatgaat gcggtcttgg actttacaac tcaactgctg
    10501 cctgaaaata aacctcgtta tctgatgggt gtgggagcgc cagatagctt gatcgatggg
    10561 gtcattcgtg gggtggatat gtttgactgt gtcttaccga ctcgaattgc tcgtaacggg
    10621 acttgtatga ccagtcaagg acgtttggtt gtgaaaaatg cccagtttgc tgaggacttt
    10681 acgccactgg atcctgagtg tgattgctac acatgtaata actatacacg cgcttacctt
    10741 cgtcacctgc tcaaggctga tgaaaccttt ggtatccgct tgactagcta ccacaatctt
    10801 tacttcttgc ttaacctgat gaagcaagtg cgacaagcca tcatggatga caatctcttg
    10861 gaattccgtg agtattttgt ggaaaaatat ggctataata agtcaggacg taatttctaa
    10921 aatggaattg atataaaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    10981 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    11041 gattaggatt ataggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    11101 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    11161 actcattgaa gaattttcta agaacaatga gattgatttg ataggatttt ttagaagacg
    11221 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    11281 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgggcg tcttaggctt
    11341 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    11401 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    11461 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatggtctt
    11521 tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    11581 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    11641 aggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg tcaagcagtt
    11701 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    11761 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    11821 acttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    11881 acatcatata caggagtcga agattatcag ctttttagcg gatactagct atgcggttta
    11941 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    12001 attactgact ctgatttgtt cttatggctt tgccagtctg tcattttatg tattggaacc
    12061 ttggattgca ggcaagaaca cacctattgt ccaaaccctt cgtcccctgc cttatattca
    12121 cgcaattctt gcagcaggta caggaatctt gaccatcatt gtctgcacgg tgaccttgtt
    12181 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    12241 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    12301 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    12361 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    12421 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    12481 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    12541 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    12601 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    12661 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg ctggaacaga
    12721 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    12781 tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa aataacttgt
    12841 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    12901 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgtag
    12961 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    13021 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    13081 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    13141 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    13201 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    13261 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    13321 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    13381 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    13441 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    13501 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    13561 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    13621 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    13681 ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg tcaccacgta
    13741 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    13801 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    13861 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    13921 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    13981 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    14041 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    14101 gcaacctacc tagatggcgt aaaacgttat caagcataag agagaaagca gaagttagag
    14161 actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt aaaaaaatca
    14221 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    14281 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    14341 tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt gcgtattgta
    14401 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    14461 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    14521 tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    14581 tactactgta aaaaaggaat ttatgctcac tgtgaagacg aagggggttg gattttcggt
    14641 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    14701 taccatactc cagaagactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    14761 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag cgtagccatt
    14821 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    14881 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    14941 actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta tgatttgaca
    15001 gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac atttgatttc
    15061 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    15121 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    15181 tctacaaata cgactccaca attgttgaaa gcacttgaaa gtcataagat tgaaccggaa
    15241 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga agtcttcagt
    15301 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    15361 gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc agatggctgg
    15421 attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc ggaattggtt
    15481 ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat gtacggagat
    15541 tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag tagaaaattt
    15601 gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt ggaacaagaa
    15661 tcgcctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc ggaagaccaa
    15721 cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc tcttttgcag
    15781 gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag
    15841 gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt tttggagttg
    15901 ctttttttat ttttctaact ctttgcgaat agtataggtg aggaggtaag tatggttcaa
    15961 gaaattgcac aagaaatcat tcgttcagct cggaaaaaag ggacgcagga tatctatttt
    16021 gtccctaagt tagacgccta tgagcttcat atgagggtag gagacgagcg ctgtaaaatt
    16081 ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt tgtggcgggt
    16141 atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc ctatgaccat
    16201 aagatagcgt ctctacgttt atctactgta ggcgattatc gggggcatga gagtttggtt
    16261 atccgtttgt tgcacgatga ggagcaggac ctgcattttt ggtttcagga tattgaagaa
    16321 ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt tgggagtggt
    16381 aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca agttatgtcc
    16441 atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt gaacgaagca
    16501 atcggcctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc agatctcttg
    16561 attatcggag aaattcgtga cagcgagacg gcgcgtgcag tggtcagagc tagtttgaca
    16621 ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta tgagcgtctg
    16681 ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt ctgctaccag
    16741 agattaatcg ggggaggagg aatcgttgac tttgcaagca gagattatca agaacaccaa
    16801 gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat cacaagtctt
    16861 caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca ccctatttaa
    16921 caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag ataggagtgc
    16981 tttgttggac aagcagtgtg tgacccagat gcgtgtgggc ttgtctcagg ggaaatcatt
    17041 ctcagaaatg atggaaagtt tgggatgttc aagtgctatt gtcactcagt tatccctagc
    17101 tgaagttcat ggcaatctcc acctgagttt gggaaagata gaagaatatc tggacaatct
    17161 ggctaaggtc aagaaaaaat tgattgaagt agcgacctat cccttgattt tgctgggttt
    17221 tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg atagtagcaa
    17281 tattgccacc caaattatcg gtaatctgcc ccaaattttt ctaggcatgg tagggcttgt
    17341 ttccgtgctt gcccttttag cactcacttt ttataaaaga agttctaaga tgagtgtctt
    17401 ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact tgacagccta
    17461 ttatgcacgt gaatggggga atatgatttc acagggaatg gagttgacgc agatttttca
    17521 aatgatgcag gaacaaggtt cccagctctt taaagaagtc ggtcaagatc tggctcaaac
    17581 cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct ttaggaagga
    17641 attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg agttggaaat
    17701 ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca tgaatttggt
    17761 gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg cggcaatgct
    17821 catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg atgacattct
    17881 tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc ttgctgatta
    17941 tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg
    18001 acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt tatagcttag
    18061 aaaagaatga agatgctagc ctaagaaagt tacaagcaga tggacgcatc acggaagaac
    18121 aggctaaagc ttataaagaa taccatgata aaaatggagg agcaaatcgt aaagtcaatg
    18181 attaaggcct ttaccatgct ggaaagtctc ttggttttgg gacttgtgag tatccttgcc
    18241 ttgggcttgt ccggctctgt ccagtccact ttttcagcgg tagaggaaca gattttcttt
    18301 atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagctag tcaacaaaag
    18361 actagtctga acttggatgg gcagatgatt agcaatggca gtcaaaagtt gacagttcct
    18421 aaaggaattc aggcaccatc aggccaaagt attacatttg accgagctgg gggcaattcg
    18481 tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca attatatcta
    18541 ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga ttttactgga
    18601 agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg gacaaattca
    18661 aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa
    18721 gatggccctg cagacggggc aaaatcaggt aagcatcaac ggagttgaga ttcaggtatt
    18781 ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg caatcaaaga
    18841 gccataaggt caaggctttt accttgttag aatccctgct tgccctcatt gtcatcagtg
    18901 ggggattact cctttttcaa gctatgagtc agctcctcat ttcagaagtt cgctaccagc
    18961 aacaaagcga gcaaaaggag tggctcttgt ttgtggacca acttgaggta gaattagacc
    19021 gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat ggcaaggaca
    19081 tcgccatcgg taagtcaaag tcagatgatt tccgtaaaac gaatgctcgt ggtcgaggtt
    19141 atcagcctat ggtttatgga ctcaaatctg tacggattac agaggacaat caactggttc
    19201 gctttcattt ccagttccaa aaaggcttag aaagggagtt catctatcgt gtggaaaaag
    19261 aaaaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat ctttagtctt
    19321 ttgttgcaat tttatttgaa ccgacaagtc gcccactatc aagactatgc tttgaataaa
    19381 gaaaaattgg ttgcttttgc tatggctaaa cgaaccaaag ataaggttga gcaagaaagt
    19441 ggggaacagt tttttaatct aggtcaggta agctatcaaa acaagaaaac tggcttagtg
    19501 acgagggttc gtacggataa gagccaatat gagtttctgt ttccttcagt caaaatcaaa
    19561 gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa agtggagaag
    19621 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcat agtcaattca actataatgc
    19681 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    19741 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ttaaagatat
    19801 gaaacatgat tttaaccaca aagcagaaac tttcgattcc cctaaaaata tcttcctcgc
    19861 aaacttggta tgtcaagcag ccgagaaaca gattgatctt ctatcagaca aagaaatttt
    19921 agatttcggt ggtggcacgg gtctattagc cttgccccta acccctagcc aagcaggcta
    19981 agtcagtcac tcttgtagac atttctgaga aaatgttgga gcaagctcgt ttgaaagtgg
    20041 agcagcaagc aatcaagaat atccagtttt tggagcaaga tttaccgaaa aatcccttgg
    20101 agaaagagtt tgattgcctt gctgttagtc gggttcttca tcatatgcct gatttggatg
    20161 cggctctctc actgtttcat caacatttga aggaagatgg gaaactcatc attgctgatt
    20221 ttaccaagac agaagctaat catcatggat ttgatttagc tgaactggaa aacaagctaa
    20281 ttgagcatgg tttttcatct gtgaatagtc agattctcta tagcgctgaa gacctgtttc
    20341 aaggaaatca ctcagaattc tttttaacag tagcccaaaa atcactcgcc tagtcaggga
    20401 gtgatttttc tataaggatg gaaaaaagaa gggaaatttg ataagatagg aatatggatt
    20461 ttgaaaaaat tgaacaagct tatacctatt tactagagaa tgtccaagtt atccaaagtg
    20521 atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat ctggatggtg
    20581 aaactgagct aaaccaggtc aaagacaaca atcaggccct taagcgttta gcactacgca
    20641 aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctgggcaa acagaaccct
    20701 tgcaggccaa tcaccagttt acaccagatg ccattgcttt gcttttggtg tttattgtgg
    20761 aagagttgtt taaagaggag gaaattacta tcctcgaaat gggttctggg atgggaattc
    20821 taggcgctac tttcttgacc tcgcttgata aaaaggtgga ttacttggga atggaaatgg
    20881 atgatttgct gattgatctg gcagctagca tggcagatgt aattggtttg caggctggct
    20941 ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagcgatgtg gtcatcagtg
    21001 acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa gttgcttcta
    21061 gccaagaaca tacttacgcc catcacttgc tcatggaaca agggcttaag tacctcaagt
    21121 cagacggata cgctattttt ctagctccga gtaatttgtt gaccagtcct caaagtgatt
    21181 tgttaaaaga atggctgaaa gaagaggcga gtctggttgc tatgattagt ctgcctgaaa
    21241 atctctttgc taatgccaaa caatctaaga ctatttttat cttacagaag aaaaatgaaa
    21301 tagcagtaga gccttttgtt tatccacttg ctagcttgca agatgcaagt gttttaatga
    21361 aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat agattttgtt
    21421 ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa ttgcaatcaa
    21481 tgcaggaagt tcaagtttga aatggcaatt atacttaatg ccagaggaaa aagtgttagc
    21541 caaaggtttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa aatttgacgg
    21601 ccgttctgaa caacaaattt tggatattga aaatcataca caagccgtta aaattttatt
    21661 ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag gtgttggaca
    21721 tcgtgttgtt gctggtggag aatatttcaa agaatcaaca gttgttgagg gagatgtttt
    21781 agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcca atgcagcagg
    21841 tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt ttgatacttc
    21901 cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa aatattacac
    21961 agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg tagcaggaga
    22021 agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct gtcatattgg
    22081 taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt ctatggggtt
    22141 cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc cagctatcat
    22201 tccttattta atgcaatata cagaggattt taacacacca gaagatatca gtcgtgttct
    22261 taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc gcgatataga
    22321 agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt atgttgaccg
    22381 tatccaaaaa catatcggtc agtaccttgc agtgctaaat ggagcagatg ccattgtttt
    22441 cacagcaggt gtcggtgaaa atgcagagag tttccgtcgt gatgtaatct cagggatttc
    22501 gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag gagacatctc
    22561 aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat tagtcattgc
    22621 ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa tacaaggagt
    22681 tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc ttgctatgat
    22741 tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt tgagttttga
    22801 agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag gaggggacaa
    22861 gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaac cattttcgag
    22921 taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa attaagcgac
    22981 ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc gactttgttg
    23041 tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa aatctactcc
    23101 atgtattaaa attatcaaag atttaccggg aaggaaatgg gagtgaaaaa gaaactaaag
    23161 ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcgac taatggggta
    23221 actagcgata ttacagccga atcggctgat ttttggagta aattggttta cttctttgcg
    23281 gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat tctctttacg
    23341 gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc ttctaggaaa
    23401 atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg tcgagatatg
    23461 gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat gggtgtcaga
    23521 cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc cctgttccaa
    23581 gccctatcaa gagttgactt tttaaagaca ggtcatttct tatggattaa ccttggtagt
    23641 gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt aagtacttgg
    23701 ttgtccaaca aagctttgtc tgaacgaaat ggcgctacga ctgcgatgat gtatgggatt
    23761 ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct atactggaca
    23821 gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt caagattatc
    23881 gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa aagaaaagcc
    23941 aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt agtatttaca
    24001 ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat tccaagaatg
    24061 aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct atttggtaaa
    24121 aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa agcaaatcaa
    24181 caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt gaagacggtt
    24241 agtgaagaaa ccgttgacct tggtcatgtg gttgatgcta ttaaaaaaat agaggaagaa
    24301 ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag acatgccagc
    24361 actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat cgaggaagcg
    24421 atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac tgaaaatcaa
    24481 gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca ggtggctacg
    24541 gatgtgactg cttatgttca aacgattatt gatgacatgg atgttgaggc tacactttca
    24601 aatgattata accgtcgtag catcaatttg caaattgata ctaacgaacc aggtcgtatt
    24661 atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa ttatctttac
    24721 aactgctatt caagaacctt ctatatcact attaatgtca atgattatgt tgaacaccgt
    24781 gcagaagtct tgcagaccta tgcgcaaaaa ttggcgattc gtgttttaga agaagggcgc
    24841 agtcatcaaa cagatccaat gtcgaatagt gaacgcaaga ttatccaccg tattatttca
    24901 cgtatggatg gcgtgaccag ttactctgaa ggtgatgagc caaatcgcta tgtcgttgta
    24961 gatacagaat aagtaaaatc agggttgacc tgattttttg ctagctagag gaggttaaac
    25021 tgatgttgaa taagataaga gactatctag acttttctgg tttgcagtac cgtagtcctg
    25081 ataaagcggg agcagagcga gagaagatgc tggcgttccg ccacaaagga caagaggccc
    25141 gaaaggcttt tacagaactg gccaaagcct ttcaagcaag ccatccagaa tggcaactcc
    25201 aacagactag tcagtggatg aatcaggccc agcgtttgag accacatttt tgggtttatc
    25261 tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat gggacatcta
    25321 ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat gagcaaacac
    25381 tgggcaagca gaccaaagtt ttagacattc caaccgttaa agggatttat tatctaacct
    25441 actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt actttacgcg
    25501 agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt cctatgacag
    25561 aaaattcgtc tgaagaagaa atcgtagaag gcttattgaa gtcttattct aaaattcttc
    25621 cctattatct agctacgaga aaataagata atttgtaaaa catcataaat catacagtcc
    25681 aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc gcattatata
    25741 ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc aagtgttcta
    25801 aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt attggtgttg
    25861 ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt tgttaaagca
    25921 acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac ctttcgtcca
    25981 atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga cccttacttt
    26041 ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt tggaactgca
    26101 actacagctc tattgattgg ttttggaata aatatcttgc tcgtagctct tcgaaagatt
    26161 acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc tgcaacagta
    26221 tcttttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac agcagcgatt
    26281 ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga ggcaactcaa
    26341 cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc aatctggttt
    26401 gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa tcttaaatta
    26461 cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt gatgctcgta
    26521 ttcttcggag ccattctttt aatcttgggt ccagacatta tgtctaataa agaagtcatc
    26581 acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat tatccaaaca
    26641 gcctttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat gttcgtatct
    26701 gagttgacaa acgccttcca aggtatttca aacaaattgt tgccaggttc attcccagcg
    26761 gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcctgtc aggatttatc
    26821 tttggtttga ttggtcaatt gattacaatt gttttgctca tcgtctttaa aaatccgatt
    26881 cttattatta taggatttgt accagtgttc tttgacaatg cagccattgc ggtctacgct
    26941 gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg tgtccttcaa
    27001 gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg tggctaccat
    27061 ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa ataccttggt
    27121 attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact tcaatttgcc
    27181 aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc ttagtatcta
    27241 gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa tgggttcatc
    27301 aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa cagattttac
    27361 agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg acatcgtaat
    27421 cgcttctctt catttgattc aagaattgga agggtgaact aatgggaagt taattgggct
    27481 tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac tacagtaaaa
    27541 ggttggaggg ggctggacag aaactgagag ttatcgtttc tgtccttctc cctctttaaa
    27601 taaaggaggc agatatgaat ttaaaacaag ctttaattga caacgactcg atccgactag
    27661 gtttagaggc taacgattgg aaagaagcag tcaaggtagc agtagatccc ttgattgaaa
    27721 gtggggcaat tttgccagag tattacgatg ctatcattga atcgactgaa gagtatgggc
    27781 cttactatat cttgatgcca ggtatggcta tgccccacgc tagacctgaa gctggtgtgc
    27841 aaagtgatgc cttttcatta attaccttac aaaatcctgt tgtattttca gatgggaaag
    27901 aggtatctgt tttgttggca ctagcagcaa caagttcaaa aattcacaca agtgtagcca
    27961 ttccacaaat tattgccctg tttgaattag aagattctat tgcacgttta caggcttgcc
    28021 agactaaaga agatgtcttg gctatgattg aagaatctaa ggatagccct tatctcgaag
    28081 gattggattt ggaaagttag aaagaggaat aaagaaatga caaaaagaat acctaattta
    28141 caagttgcat tagaccattc agacttgcaa ggagcgatta aagcagctgt ttctgttggt
    28201 caggaagtag atattatcga agctggaact gtttgcttgc ttcaagttgg aagtgaactg
    28261 gctgaagtct tgcgtagcct tttcccagat aagattattg tggcagacac aaaatgtgct
    28321 gatgctggtg gaacagttgc taaaaataat gcggttcgtg gagcagactg gatgacttgt
    28381 atctgttgtg caaccatccc tactatggaa gcagctctaa aggctatcaa gactgaacga
    28441 ggagaacgag gcgaaatcca gatcgagctt tatggcgatt ggacttttga acaagctcag
    28501 ctttggctag atgcaggtat ctcacaagct atttatcacc aatctcgtga tgctcttctt
    28561 gctggtgaaa cttggggtga aaaagacctt aataaggtta aaaaactcat tgacatgggc
    28621 ttccgtgtat ctgtaacagg tggtctagat gtagatactc tcaaactctt tgaaggtgtt
    28681 gatgtcttta cctttatcgc aggtcgtgga attacagagg ctgtggatcc agcaggagca
    28741 gcgcgtgcct tcaaggatga aatcaaacga atttgggggt aaatcatggt acgtccaatt
    28801 ggaatttatg aaaaggcaac cccaacacac tttacttggc tagaacgttt aaattttgcc
    28861 aaggagttag gctttgattt tatcgagatg tctattgacg aacgtgacga gcgtttagca
    28921 agacttgact ggagtaagga agaacgcttg gaagttgtca aagaaatcta tgaaactggt
    28981 gttcgtattc cttctatctg tttttcaggc catcgtcgct acccattggg atcaaaagat
    29041 tcagttctag aggaaaaatc tctagaactc atgaaaaaat gtatcgaatt agctcaagac
    29101 ttgggagttc gtacgattca attagctggt tacgatgttt actatgagga aaagtcaccc
    29161 cagacacgcc aacgttttat caaaaatttg agaaaatcct gtgactgggc tgaagaagct
    29221 caggtggtac ttgctattga aattatggat gatcctttca tcagtagcat cgaaaaatat
    29281 ttggctatag aaaaagagat tgactctccc ttcctctttg tatatccaga tattggtaat
    29341 gtgtctgcat ggcataatga tatctatagt gagttttatc ttggtcatca tgccatcgca
    29401 gctctccatc tcaaggatac ttatgcagtg acagaaagtt caaagggcca gttccgagat
    29461 gtacctttcg ggcaaggttg tgtcaaatgg gaagaagctt tcgatatttt aaaggaaacc
    29521 aattataatg gacctttcct aatcgaaatg tggtctgaaa attgtgaaac agtagaagaa
    29581 acacgcgcag ccattcaaga ggcgcaagct tttctctatc cactcattaa gaaagcaggt
    29641 ttgatgtaag atgaatcaag taatcaatgc tatgcgtaaa cgagtctgtg atgccaatca
    29701 atcattgcca aaacatggac ttgtcaaatt tacctggggg aatgtatctg aagttaatcg
    29761 cgaactcggt gtcattgtta tcaaaccatc aggcgtggat tatgacgaat tgacacctga
    29821 aaacatggta gtgactgatc tagatggtaa gatcctagaa ggggatttaa gaccatcttc
    29881 cgacctccca actcatgtgc aattatataa ggcttggtca gaaattggta gtgtggttca
    29941 cacccattcg acagaagctg ttggttgggc tcaggcaggt cgtgatattc ctttctacgg
    30001 aacaacccat gcagattatt tctacggttc aatcccttgc gcccgtagtt tgaccaagga
    30061 cgaagtagaa gtggcctatg aaaaagatac tggcctggtt atcgtagaag agtttgaaca
    30121 tcgcggactt aacccggttg aagtaccagg aattgttgta cgcaatcacg gtccattcac
    30181 ctggggcaaa aatccagaga atgctgttta tcactctgtc gtactagagg aagtatcaaa
    30241 gatgaatcgc tttacagaac aaatcaatcc aagagttgga cctgctcccc agtacatact
    30301 agaaaaacac taccaacgta aacatggacc aaatgcttat tatggtcaaa agtaagaacg
    30361 atgaaggagg agaaaaagat aaatttagct cctcttttta catttgattt ttattgagag
    30421 taaagttgga attgaagtaa ttttaaaaga ttttttagaa atagcgcttg atatatatat
    30481 ggtaaaataa aaagaattgc tgtgatatca atagatttgg gggatttttt aatatggtac
    30541 tggataaggc aagttgtgat ttgcttcaat atttgatgga tcaagaaacg tccaaaacga
    30601 ttatggcgat ttcgaaagat ttgaaagagt caagaaggaa aatttattat cacattgaca
    30661 aaatcaatgc tgctctgggt gacgaggcgc ttcacatcat tagtattcca cgaattggta
    30721 ttcacttaac ggaagagcag agagatgctt gttgtaaact attatcggaa gtagattcgt
    30781 acgattatat catgagtgcg catgaacgta tgatgataat gttactatgg ataggtattt
    30841 ctaaagaacg tattacgatt gaaaaattga tagagttaac agaggtatct aggaatactg
    30901 ttctcaatga tttgaatagt attcgttatc aactaacttt ggaacaatat caggtgatct
    30961 tgcaagtgag caagtcacag ggataccacc ttcatgccca ccctcttaat aaaattcagt
    31021 atcttcaatc gcttctatat catattttta tggaagaaaa tgccactttt gtatctattt
    31081 tagaagataa gatgaaagag aggttagatg atgagtgttt gctttctgtt gaaatgaacc
    31141 aattttttaa ggaacaggtt cctttagttg aacaagattt agggaagaaa ataaaccatc
    31201 atgaaataac ttttatgttg caggttctac cttatttgct gttaagctgt cataatgttg
    31261 aacagtatca agaaagacat caggatatag agaaagaatt ttctttgata agaaaaagaa
    31321 tagagtatca ggtgtctaag aaattaggag aacggttgtt tcaaaagttt gaaatttctt
    31381 tgtcaggact tgaagtttct cttgtagctg ttctcctcct ctcctatcgt aaagatttgg
    31441 atattcatgc agaaagtgat gattttcggc aattaaaact tgctttagaa gaatttatct
    31501 ggtattttga atcacaaatc cgaatggaga ttgagaacaa ggatgatttg ttacgaaatt
    31561 tgatgatcca ctgtaaagcc ttgttattta gaaagactta cggtattttt tctaaaaatc
    31621 ctctaacaaa acaaattcga tccaagtatg gagaattatt tttagtcact agaaaatctg
    31681 cggaaatttt agaaggagca tggtttattc ggctaacaga cgatgatatt gcctatttga
    31741 cgattcatat tggaggattt ttaaaatata caccatcgtc tcaaaaaaat atgaaaaaag
    31801 tttatctcgt ttgtgatgaa ggtgttgcgg tttcgagact tttgctgaaa caatgcaaac
    31861 tttattttcc aaatgagcaa attgacactg tatttacaac agaacaattt aagagtgtgg
    31921 aagatattgc acaagttgat gtagtgatta ctactaatga tgatttggat agcagatttc
    31981 cgattttaag ggttaatcct atccttgaag cagaagatat tttgaaaatg ctagactatc
    32041 ttaaacacaa tatatttcgt aataagagca aaagtttcag tgaaaatctt tctagtctta
    32101 tttcgtctta tattgtagac agcaagttgg ctagtaagtt ccaagaagag gttcaaacac
    32161 ttataaatca agaaatagta gttcaagctt ttttggaaga tatttgaagg acagtccaat
    32221 gatgaacaca aacctgtgtt tttcttggtc ttttttagtg ttttgaaggg tggtatacta
    32281 atctcaaaga taacaattat atccaaagga ggcaacatat gccaaacgtc aaagaaatta
    32341 caagagagtc atggatttta gccactttcc cagagtgggg aacatggttg aacgaagaaa
    32401 tcgaagaaga agtcgtacct gaaggcaact ttgccatgtg gtggctaggc aactgtggta
    32461 cttggattaa gacaccagct ggtgctaacg ttgtcatgga cctttggtca aaccgtggaa
    32521 aatcaaccaa aaaagtgaaa gatatggttc gtgggcacca aatggcaaat atggcaggtg
    32581 ttcgtaagtt gcaaccaaac ttgcgtgttc agccaatggt tatcgatcca tttgctatca
    32641 acgaactaga ctattactta gtttcacact tccacagtga tcatatcgac ccatacacag
    32701 ctgcagcaat tctcaacaat cctaagttag agcatgttaa gtttatcggt ccttaccact
    32761 gtggacgaat ctgggaagga tggggtgttc caaaagaacg tatcatcgtt gttaaaccag
    32821 gtgacactat cgaattaaaa gatatgaaga ttcatgcagt agaatcattt gaccgtactt
    32881 gcttggtaac tctcccagtg aacggtgctg atgagacagg cggtgaactt gctggcttgg
    32941 ctgttacaga tgaagaaatg gctcaaaagg ctgttaacta tatctttgaa acaccaggtg
    33001 gaaccatcta tcatggtgca gattctcact tctcaaacta ttttgcaaaa catggtaaag
    33061 actttaaaat tgatgttgct ttgaataact atggtgaaaa tccggtaggt atccaagaca
    33121 aaatgacatc tatcgacctt cttcgtatgg cagaaaatct gcgtaccaaa gtcattatcc
    33181 cagttcacta tgatatctgg tctaacttca tggcttctac taatgagatt ctagaacttt
    33241 ggaaaatgcg aaaagatcgc ttgcaatacg atttccatcc atttatctgg gaagttggcg
    33301 gtaagtacac ttatcctcaa gatcaacact tagtagaata ccatcatcca cgtggttttg
    33361 atgattgttt tgaacaagac tctaacattc aatttaaagc tttgctataa tataaaaata
    33421 ttctttggag gttatccgta tgttgcatga tacggataat tttcatataa tagtaaaata
    33481 gaatgtgtga ttcaataatc acctcaaata gaaaggaaat tctatgtcaa atctatctgt
    33541 taatgcaatt cgttttctag gtattgacgc cattaataaa gccaactcag gtcatccagg
    33601 tgtggttatg ggagcggctc cgatggctta cagcctcttt acaaaacaac ttcatatcaa
    33661 tccagctcaa ccaaactgga ttaaccgcga ccgctttatt ctttcagcag gtcatggttc
    33721 aatgctcctt tatgctcttc ttcacctttc tggttttgaa gatgtcagca tggatgagat
    33781 taagagcttc cgtcaatggg gttcaaaaac accaggtcac ccagaatttg gtcatacggc
    33841 agggattgat gctacgacag gtcctctagg gcaagggatt tcaactgcta ctggttttgc
    33901 ccaagcagaa cgtttcttgg cagccaaata taaccgtgaa ggctacaata tctttgacca
    33961 ctatacttac gttatctgtg gagacggaga cttgatggaa ggtgtctcaa gcgaggcagc
    34021 ttcatatgca ggcttgcaaa aacttgataa gttggttgtt ctttatgatt caaatgatat
    34081 caacttggat ggtgagacaa aggattcctt tacagaaagt gttcgtgacc gttacaatgc
    34141 ctacggttgg catactgcct tggttgaaaa tggaacagac ttggaagcca tccatgctgc
    34201 tatcgaaaca gcaaaagctt caggcaagcc atctttgatt gaagtgaaga cggttattgg
    34261 atacggttct ccaaacaaac aaggaactaa tgctgtacac ggcgcccctc ttggagcaga
    34321 tgaaactgca tcaactcgcc aagccctcgg ttgggactac gaaccatttg aaattccaga
    34381 acaagtatat gctgatttca aagaacatgt tgcagaccgt ggcgcatcag cttatcaagc
    34441 ttggactaaa ttagttgcag attataaaga agctcatcca gaactggctg cagaagtaga
    34501 agccatcatc gacggacgtg atccagtcga agtgactcca gcagacttcc cagctttaga
    34561 aaatggtttt tctcaagcaa ctcgtaattc aagtcaagat gccttgaatg ttgtggcagc
    34621 taaattacca accttcctag gtggatcagc tgaccttgct cactcaaaca tgacttatat
    34681 aaagacggat ggacttcaag acgatgccaa tcgcttgaat cgtaacattc agtttggtgt
    34741 tcgtgaattt gcaatgggaa caatcttgaa cgggatggcc cttcatggtg gacttcgtgt
    34801 atacggtgga actttcttcg tcttctctga ctatgtgaag gcagctgtcc gcttgtcagc
    34861 cttacaagga cttcctgtga cttatgtctt tacccatgat tcaatcgcag ttggggaaga
    34921 tggtccgact cacgaaccag ttgagcattt agcaggtctt cgtgctatgc caaatctaaa
    34981 tgttttccgt ccagcagatg cgcgtgaaac tcaagcagct tggtaccttg cagtgacaag
    35041 tgagaaaaca ccaactgccc ttgttttgac acgtcaaaac ttgactgttg aagatggaac
    35101 agacttcgac aaggttgcta aaggtgctta tgttgtatat gaaaatgcag ccgactttga
    35161 taccatcttg attgcgacag gttcagaggt taatcttgct gtctcagctg ctaaagaatt
    35221 ggctagtcaa ggcgaaaaaa tccgcgtagt cagcatgcca tctacagatg tctttgataa
    35281 acaagatgca gcttacaagg aagagattct tccaaatgca gtccgccgtc gtgttgcagt
    35341 cgaaatgggt gcaagtcaaa actggtacaa atatgttggt ctcgatggtg ccgttctagg
    35401 tattgatacc ttcggagcct ctgccccagc accaaaagta ttggcagaat atggctttac
    35461 tgtagaaaat cttgtaaaaa ttgttcgaaa cttgaaataa tcctaaaaat cagggcgtaa
    35521 gctctggttt ttcttaccag aaaagtaagg tacaatcttg taaaagtagc tgaaatttga
    35581 tatagtagtc ctatgtaaaa gacaaaggag aaaacaatga atccaaatat tactttttta
    35641 atcatgcttg taggtatgat ggccttgatg ttctttatgc aacgttctca aaagaaacaa
    35701 gctcaaaagc gtatggaaag cttaaataaa ctacaaaaag gctatgaagt gattacaatc
    35761 ggtggacttt atggaacagt cgatgaagta gatacggaga agggaacaat agttcttgac
    35821 gtagatggag tttacttgac ttttgaacta gctgctatca agacagtatt accgctgaaa
    35881 gaaacagctt cactagaagg cgcaattgaa aaataagacg ggatcacgaa ctcccgtttt
    35941 tctataaaag aaaggaaatg ggatgaaaaa attagtcttt gtctgtctgg gaaatatttg
    36001 ccgtagccct atggccgagt ttgttatgaa atcaatgaca gataactacg aaatccaaag
    36061 tcgagcaact tcctcttggg aacatggcaa tccgattcat aaggggactc agggaatttt
    36121 tcaagagtat gagattcctt atgacaagaa caagacatcg cttcagatta gtaaggaaga
    36181 ttttgaagcc tttgattata ttatcggaat ggacgcttca aatgtttccg acttacgtca
    36241 gatgtgtcca gtagactgtc aagataagat ttactcattt tcatctgaaa gtgttccaga
    36301 cccttggtat acaggagatt ttgaagaaac ctatcgacgt gttcaagagg gttgtcaagc
    36361 ttggttagaa cgtttagaaa aggagagtta aggtggaaaa tcttacgaat ttttacgaaa
    36421 agtatcgtgt ttatctgact cgtccacgtt tagagatttt ggcagtagtt accattgttt
    36481 tctgtgctgt actcgtcttt tttctaaata ttccaggaaa aggtgtctta aaactcgata
    36541 atggaacgat tgtttatgat ggcagtcttg tccgcggtaa aatgaatggc caaggtacca
    36601 ttaccttcca aaatggagac caatatacag gtggcttcaa caatggagcc ttcaacggaa
    36661 aaggtacctt tcaatctaaa gaaggctgga cctacgaagg tgattttgta aatggtcagg
    36721 ctgaaggaaa agggaaacta acaacagaac aagaagtcgt ttatgaagga acttttaaac
    36781 aaggcgtttt tcaacaaaaa taaagcctcc ttatcaaagg aggtattatt agaatcgcaa
    36841 ggtaagcgct tacttgcaaa tccctttctt tccaaatccc tcttccaacc aagtttgtga
    36901 aataaaaaat atttgaaata aatttcacaa acttcaaaga taaaacctga taagaaaaga
    36961 aaatgagaaa agtttcacaa gagtttaaaa attctttgtg aaatgtttat gaaactgttt
    37021 acaaagttga aataatacgt tataataaac ttgtgaaaaa attaacaaag gatatcgttc
    37081 cttgaaagct atggaggaaa atatggctga taaaaaaact gtgacaccag aggaaaagaa
    37141 actcgttgct gaaaaacacg tagatgagtt ggttcaaaaa gctctagttg cccttgaaga
    37201 aatgcgtaaa ttggatcaag agcaagttga ctacatcgtt gccaaagcat cagtagcagc
    37261 tttggatgcc cacggagaat tggctttaca tgcctttgaa gaaacaggac gtggtgtatt
    37321 tgaagacaaa gcaactaaga acttgtttgc ctgtgaacac gtagtaaaca acatgcgcca
    37381 cactaagaca gttggcgtta tcgaagaaga cgatgtaaca ggattgactc ttattgctga
    37441 accagttggt gttgtttgtg gtattactcc aacaacaaac ccaacatcaa cagcaatctt
    37501 caaatcattg atttcattga agacacgtaa cccaatcgtc tttgccttcc atccatcagc
    37561 acaagaatca tctgctcatg cagctcgtat cgtccgcgat gcagctatcg cagctggtgc
    37621 tcctgaaaac tgtgtgcaat ggattactca accatctatg gaagcaacaa gtgcccttat
    37681 gaaccacgaa ggtgttgcga caatccttgc aacaggtggt aatgccatgg ttaaggcggc
    37741 ttattcatgt ggtaaaccag ctcttggggt aggtgccgga aacgttccag cttatgttga
    37801 aaaatcagca aacattcgtc aagcagcaca cgatatcgtc atgtctaaat catttgataa
    37861 cggtatggtc tgtgcatctg aacaagcagt tatcattgat aaagaaattt acgatgaatt
    37921 tgtagcagag ttcaaatctt accacactta ctttgtaaac aaaaaagaaa aagctcttct
    37981 tgaagagttc tgcttcggcg tcaaagcaaa cagcaaaaac tgtgctggtg caaaattgaa
    38041 cgctgacatc gttggtaaac cagcaacttg gattgcagaa caagcaggat ttacagttcc
    38101 agaaggaaca aacattcttg ctgcagaatg taaagaagtt ggcgaaaatg agccattgac
    38161 tcgtgaaaaa ttgtcaccag ttattgcagt tttgaaatct gaaagccgtg aagatggtat
    38221 tactaaggct cgtcaaatgg ttgaatttaa cggtcttgga cactcagcag ctatccacac
    38281 agctgacgaa gaattgacta aagaatttgg taaagctgtt aaagctattc gtgttatctg
    38341 taactcacct tctacttttg gtggtatcgg ggacgtttac aatgccttct tgccatcatt
    38401 gacacttgga tgtggttctt acggacgcaa ctcagttggg gataacgtta gtgccattaa
    38461 cctcttgaat atcaaaaaag tcggaagacg gagaaataac atgcaatgga tgaaacttcc
    38521 ttcaaaaaca tactttgaac gtgattcaat tcaatacctt caaaaatgtc gtgacgttga
    38581 acgtgtcatg atcgttactg accatgccat ggtagagctt ggtttccttg atcgtatcat
    38641 cgaacaactg gaccttcgtc gcaataaggt tgtttaccaa atctttgcgg atgtagaacc
    38701 ggatccagat atcacaactg taaaccgtgg tactgagatt atgcgtgcct tcaaaccaga
    38761 taccatcatc gcactcggtg gtgggtctcc aatggatgct gccaaagtaa tgtggctctt
    38821 ctacgagcaa ccagaagtgg acttccgtga ccttgtccaa aaattcatgg atatccgtaa
    38881 acgtgccttc aagttcccat tgcttggtaa gaagactaaa ttcatcgcga ttccaactac
    38941 atctggtaca ggatctgaag taacaccatt tgccgttatc tctgataaag caaacaaccg
    39001 taaataccca atcgctgact actcattgac accaactgtg gcaatcgtag atcctgcttt
    39061 ggtattgaca gttccaggat ttgttgctgc tgatactggt atggacgtat tgactcacgc
    39121 gacagaagca tacgtatcac aaatggctag tgactacact gatggtttag cacttcaagc
    39181 cattaaattg gtctttgaaa atctcgaaag ctcagttaag aatgcagact tccactcacg
    39241 tgagaaaatg cataacgctt caacaatcgc tggtatggcc tttgccaatg ccttcctagg
    39301 tatttctcac tcaatggccc ataagattgg tgcgcaattc cacacaatcc acggtcgtac
    39361 aaatgccatc ttgcttccat acgttatccg ttacaacggt acacgtccag ctaagacagc
    39421 aacatggcct aagtacaact actaccgtgc agatgaaaaa taccaagata tcgcacgcat
    39481 gcttggactt ccagcttcta ctccagaaga aggggttgaa tcttacgcaa aagctgtcta
    39541 cgaactcggt gaacgtattg ggatccaaat gaattttaga gaccaaggaa ttgacgaaaa
    39601 agaatggaaa gaacattctc gtgaattatc cttcctggct tatgaagacc aatgttcacc
    39661 agctaaccca cgtcttccaa tggtagacca tatgcaagaa atcatcgaag atgcatacta
    39721 tggctacaaa gaaagaccag gacgccgtaa ataattgttt atcagtctag aagcaagaca
    39781 aaaactcaat ttgagggaaa gatccagtaa tttttctatg ataaaaggca tcctatcaag
    39841 gtttttgaat acctgatagg atgccttttt atgatgttga ggcctttttg ccctttttga
    39901 aaaactagaa tagaaacaaa atatatagca gattgaaact agaatagtac acatctgctt
    39961 ctaaaacatt gttagaattc gatttgactg tcctgatcga tttgttctat tcttatttca
    40021 ttttactata ctatataaaa aatatagtat agtaaa
//
LOCUS       DAVMBH010000015        38622 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVMBH010000015 DAVMBH010000000
VERSION     DAVMBH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38622
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.015"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            371..598
                     /locus_tag="VYP30_000898"
     CDS             371..598
                     /locus_tag="VYP30_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807922.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /locus_tag="VYP30_000899"
     CDS             886..3783
                     /locus_tag="VYP30_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1807923.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDKVVISNLRDNPEAKD
                     PAAPSPLNIDMVLVQDPTTKRIFSIYDMFPEGRAVFGMPKTPEKAYEKIGDKTYQILY
                     KQGESGHYTVRENGEVYNAQNQKTDYRVVVNPTEPGYRDKGNLYKGQELIGNIYFAHS
                     TKNPFRVANTSYLWMSYSDDDGKTWSAPRDITPGLRKDWMKFLGTGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="VYP30_000900"
     CDS             4798..5250
                     /locus_tag="VYP30_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1807924.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="VYP30_000901"
     CDS             5269..6606
                     /locus_tag="VYP30_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1807925.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="VYP30_000902"
     CDS             6685..7569
                     /locus_tag="VYP30_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1807926.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="VYP30_000903"
     CDS             7569..8402
                     /locus_tag="VYP30_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1807927.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="VYP30_000904"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="VYP30_000904"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1807928.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="VYP30_000905"
     CDS             10525..11628
                     /locus_tag="VYP30_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1807929.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11802..12500
                     /locus_tag="VYP30_000906"
     CDS             11802..12500
                     /locus_tag="VYP30_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1807930.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12519..14036
                     /locus_tag="VYP30_000907"
     CDS             12519..14036
                     /locus_tag="VYP30_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1807931.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14161..15489
                     /locus_tag="VYP30_000908"
     CDS             14161..15489
                     /locus_tag="VYP30_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1807932.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15741..16607
                     /locus_tag="VYP30_000909"
     CDS             15741..16607
                     /locus_tag="VYP30_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1807933.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16623..17462
                     /locus_tag="VYP30_000910"
     CDS             16623..17462
                     /locus_tag="VYP30_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1807934.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17735..18187
                     /locus_tag="VYP30_000911"
     CDS             17735..18187
                     /locus_tag="VYP30_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1807935.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18284..18628
                     /locus_tag="VYP30_000912"
     CDS             18284..18628
                     /locus_tag="VYP30_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807936.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMSWIINGIVNGLIGRYIKLGIY
                     AAKYGISMVRSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            18905..19549
                     /locus_tag="VYP30_000913"
     CDS             18905..19549
                     /locus_tag="VYP30_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1807937.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSAFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19718..20635
                     /locus_tag="VYP30_000914"
     CDS             19718..20635
                     /locus_tag="VYP30_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1807938.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            20653..21537
                     /locus_tag="VYP30_000915"
     CDS             20653..21537
                     /locus_tag="VYP30_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1807939.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21553..22404)
                     /locus_tag="VYP30_000916"
     CDS             complement(21553..22404)
                     /locus_tag="VYP30_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1807940.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22604..24661
                     /gene="pbp2b"
                     /locus_tag="VYP30_000917"
     CDS             22604..24661
                     /gene="pbp2b"
                     /locus_tag="VYP30_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1807941.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24672..25268
                     /gene="recR"
                     /locus_tag="VYP30_000918"
     CDS             24672..25268
                     /gene="recR"
                     /locus_tag="VYP30_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1807942.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25444..26487
                     /locus_tag="VYP30_000919"
     CDS             25444..26487
                     /locus_tag="VYP30_000919"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1807943.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLVYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            26571..27944
                     /locus_tag="VYP30_000920"
     CDS             26571..27944
                     /locus_tag="VYP30_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1807944.1"
                     /translation="MKLTIHEIAQVVGVKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLMP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            27931..28542
                     /locus_tag="VYP30_000921"
     CDS             27931..28542
                     /locus_tag="VYP30_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1807945.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28633..29337
                     /locus_tag="VYP30_000922"
     CDS             28633..29337
                     /locus_tag="VYP30_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1807946.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29556..30929
                     /gene="ftsA"
                     /locus_tag="VYP30_000923"
     CDS             29556..30929
                     /gene="ftsA"
                     /locus_tag="VYP30_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1807947.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30946..32205
                     /gene="ftsZ"
                     /locus_tag="VYP30_000924"
     CDS             30946..32205
                     /gene="ftsZ"
                     /locus_tag="VYP30_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1807948.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32210..32881
                     /locus_tag="VYP30_000925"
     CDS             32210..32881
                     /locus_tag="VYP30_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1807949.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32891..33430
                     /locus_tag="VYP30_000926"
     CDS             32891..33430
                     /locus_tag="VYP30_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1807950.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33430..33693
                     /locus_tag="VYP30_000927"
     CDS             33430..33693
                     /locus_tag="VYP30_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1807951.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33690..34475
                     /locus_tag="VYP30_000928"
     CDS             33690..34475
                     /locus_tag="VYP30_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1807952.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34484..35272
                     /gene="divIVA"
                     /locus_tag="VYP30_000929"
     CDS             34484..35272
                     /gene="divIVA"
                     /locus_tag="VYP30_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1807953.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35620..38412
                     /locus_tag="VYP30_000930"
     CDS             35620..38412
                     /locus_tag="VYP30_000930"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1807954.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELIYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIVEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        12059 a         6729 c         8380 g        11454 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt ttgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattag gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg aaagacatgg ggagataagg tggttatctc caatcttcga
     2041 gataatcctg aagctaaaga tcctgctgcg ccatcgcctc taaatattga tatggttttg
     2101 gttcaagacc cgacaacaaa gagaatcttc tcaatttatg atatgttccc agaaggtcga
     2161 gcagtttttg gaatgccaaa aacacctgaa aaagcttatg aaaagatagg ggataaaact
     2221 tatcaaatct tgtataaaca aggagagtct ggtcattata ctgttcgtga gaatggagaa
     2281 gtgtataatg cacaaaatca aaagacggat tatcgtgttg tagtgaatcc aacagaacct
     2341 ggctatagag ataaaggaaa tctttacaaa ggtcaggaat tgattggaaa tatctatttt
     2401 gcacacagta caaaaaatcc atttagagta gccaatacga gctatctatg gatgtcatat
     2461 agtgacgatg atggtaaaac ttggtctgca ccgagagaca ttactccagg tcttcgcaag
     2521 gattggatga agttcctagg aacaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttat ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     3841 gcctgctatc tttttttgat gacattcaag ctgatacgaa atcataagag gtatgaaact
     3901 actttcaggg tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 accaggaaag tcaaattaat ttatagaatt attttagcag tcaaggtgta ctgttatata
     4021 ttcaatatat tatatgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgttg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 ttaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gacgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag atcaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttaacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa atgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ttcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8461 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8581 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagataaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     8821 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggcaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaaa
     9721 acataatgga aaacaggtcc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcgaaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10321 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgctt tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctatttat aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg
    11701 ctagtttttg aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag
    11761 gtataataat ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag
    11821 aagccttgat tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg
    11881 aaccgcttta tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag
    11941 gtggagcagt cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca
    12001 ctaaacttcc aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca
    12061 cggctactat gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg
    12121 attgtaccaa gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta
    12181 aggagaaata tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag
    12241 cagctgtaga agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca
    12301 gtccaaaagt agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag
    12361 atgtcattgc agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg
    12421 gagtgcgagg catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct
    12481 tcgttgctag tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag
    12541 ttggaaaagc ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga
    12601 ttggtggtgc actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta
    12661 tttttcaatc aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt
    12721 cactacttct ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg
    12781 cgttagcagg agtaactggt tacttagtta tgactgcaac gatcaaagct ttagtaaaac
    12841 tttttatggc agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa
    12901 tagttgccgt atatttgcac aaccgatata acaatattca attaccttcc gctttaggat
    12961 tctttggagg ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct
    13021 ttgtcttctt tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata
    13081 tttctcaggc gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag
    13141 cagtaggctt acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg
    13201 aaactgttgc aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg
    13261 atttggccca ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa
    13321 caatgatgtt cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc
    13381 gtcgtaaaaa atacgcgggt ttgtttttgg gagttgcttt aacatctttt attaccggta
    13441 ttacagaacc aattgaattt atgtttctat tcgtcagtcc ggttctatat gttgttcacg
    13501 cattccttga tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca
    13561 cattttcagg aggtgtaatc gatttcacat tatttggaat tttgcagggg aacgctaaga
    13621 cgaattgggt tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt
    13681 ttagatggtt cattactcaa ttcaacgttc taacgccagg acgaggagaa gaagtagatt
    13741 ctaaagaaat ttctgaatcc gcagattcga cttcaaatac tgcagattat ttaaaacagg
    13801 atagcctaca aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt
    13861 gtgtgacacg tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa
    13921 aacaaattgg tgcagttgat gtcttagaag tgaagggtgg cattcaagca atctatggag
    13981 caaaagcaat cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac
    14041 ttactgactt aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca
    14101 tacaagaaat aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa
    14161 atgaaattta gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct
    14221 gcttgtggca attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa
    14281 acagaaatca cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt
    14341 ggaacttatg aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg
    14401 aaattggaaa ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca
    14461 ggaacagctc cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac
    14521 ggtaaattgg ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat
    14581 gaaaacatcg tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct
    14641 gccccattct acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt
    14701 gtaaaagaag gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag
    14761 ggttacacac caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc
    14821 tttatctcta acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact
    14881 gatgatccta aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg
    14941 atcaataatg gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa
    15001 acatcttaca caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa
    15061 gcaagtaagg tagaagtggt agaagtgcca ttcccatcag acgaaggtaa gccagctctt
    15121 gaataccttg taaacgggtt tgcagtattc aacaataaag acgacaagaa agtcgctgca
    15181 tctaagaaat tcatccagtt tatcgcagat gacaaggagt ggggacctaa agacgtagtt
    15241 cgtacaggtg ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg
    15301 gaaacaatca gcggctggac tcaatactac tcaccatact acaacactat tgatggattt
    15361 gctgaaatga gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa
    15421 ccagcagatg ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg
    15481 aaacaatagt ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata
    15541 cccccttttc cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga
    15601 aactgtcacg aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg
    15661 attttaaaac agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg
    15721 tgaaagtcaa taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag
    15781 tattattctt ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt
    15841 tctttaacta ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt
    15901 ttaaagatcc tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg
    15961 taccagttgt tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca
    16021 ttgccagatc cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg
    16081 tgacagttgt ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta
    16141 agtcaagcca catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga
    16201 tggcgattat gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg
    16261 ctgccatggg gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg
    16321 agtttcaagt tttttggaag attaaatggc caagccttct tccaacaact ctttatattg
    16381 caatcatcac aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg
    16441 gtggtccaaa ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat
    16501 tgacagaata cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg
    16561 taagctttgt tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag
    16621 ctatgcaatc tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt
    16681 tgctcttgtt gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca
    16741 aatcacaacc tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg
    16801 aaaacttcca acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat
    16861 ttatctcatt ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat
    16921 tggctaaaaa acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg
    16981 cgcttccaaa acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc
    17041 atgatactct ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca
    17101 tgaaacagtt cagtgaaaat atccctacag agttgcttga atcagctaaa atcgacggtt
    17161 gtggtgagat tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag
    17221 cccttgcaat ctttaccttc atcaatactt ggaatgacta cttcatgcaa ttggtaatgt
    17281 tgacttcacg taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg
    17341 caaccaacta tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag
    17401 tcttcctagt cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat
    17461 aatactctgc gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt
    17521 gcctgcggtt agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct
    17581 atcaagatac agaagtatat tttatagatt tagagaatat agaggttata agtgtctaca
    17641 aaatggaggg tatgcagtta ctttatgaag ttttgtcaga cacttatcaa cttaagaatg
    17701 gttttagtta actatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat
    17761 caccttttac aaagggattc atcccaattt agacaaggct atcgactacc tctaccaaca
    17821 tcgtaaagat tcattcgaat taggaaagta tgagattgat ggagataaag tctttctagt
    17881 tgttcaggaa aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta
    17941 tgcagatttg catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa
    18001 agacgaggca gtagcattcg acgaagcgag tgacattggc tttgttcatt gtcatgaaca
    18061 ctacccactc ttattgggtt atcacaattt tgcgattttc ttcccaggtg agccacatca
    18121 gccaaatggt tatgcaggca tggaagaaaa ggttcgaaaa tatctcttta aaattttgat
    18181 tgattaaaaa taggatgaat tgtttttttg taaagctttg acaatactct accatgaaat
    18241 tgatctttgt gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagta
    18301 tgctgcaaga gccagtttct tagatggaca ggggattaca gttgatgaga tgtcctggat
    18361 aattaatggc attgtgaatg gattgattgg tagatacata aaattaggta tttatgcagc
    18421 caagtatggt attagtatgg tgcgatcgat cttaagtagg gcagctgcaa ctgcggcagc
    18481 aagagtagga ttattgacca agatttttgg atggatttta cgaatagctg tgctcgcagc
    18541 tgatgtatat ggtaattttg ccaacaatat tgctgcagct tgggatgcat atgataaaat
    18601 tcctaacaat ggtcgtataa acttttaaaa tgcgagaatg aaagcacttt gtattttttt
    18661 attgaatatg ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt
    18721 tgataggcat acttggagta ctattttaat tgcttcgctg tccgggatat atgattataa
    18781 gcccatagat aaaaatagaa aaaagtccaa aagaaaaaat agatttgttc atggtaggga
    18841 cttatgaaag ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc
    18901 aaacatggca caaaaaggag taagccttat caaggcagca tttgatacag ataactttct
    18961 catgcgtttt agtgagaagg tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc
    19021 ttgtttaccc atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga
    19081 agttaagaag agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa
    19141 tctgaaacta ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc
    19201 agatctctat cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg
    19261 tttaggtatt ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg
    19321 ttatgaccta tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt
    19381 tccttggttc ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc
    19441 cgccttcagt ctactcttag gtggctcagc cttcctactt tttgggtttg gactattggt
    19501 ctttatccag actggattga tggagaaaat tttcgcaaaa taccaatagg agctttattt
    19561 ctgaaactac tttcaaaggc tccaaacgct attctataag cgagaaacta aaatctaagt
    19621 gtctataaga tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc
    19681 tgctttagca gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga
    19741 aggtgtcatt ccagccttct acgcatgtta tgatgatcaa ggagaagtaa gcccagaacg
    19801 tacgcgtgcc ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg
    19861 ttcttctggt gaatgtatct accaaagcgt tgaagatcgc aagttgattt tggaagaagt
    19921 catggcggta gctaaaggta aattgaccat tattgcccat gttgcctgca acaatactaa
    19981 agacagtatg gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat
    20041 tccaccaatt tatttccgct tgccagaata ctcagttgcc aaatactgga acgatatcag
    20101 ttctgcagct ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc
    20161 tttgactcca agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgtgaagaa
    20221 ctcttctatg ccagttcaag atatccaaac ctttgtgagc cttggtgggg aagaccatat
    20281 cgtctttaac ggtccagatg aacagttcct aggtggtcgc ctcatgggtg ccaaagctgg
    20341 tatcggtggt acttatggtg ctatgccaga actcttcttg aaactcaacc aattgattgc
    20401 ggataaagat ttagaaacag cgcgtgagtt acagtatgct atcaacgcta tcattggtaa
    20461 attgactgct acacatggaa atatgtacgg tgtcatcaaa gaagttttga agatcaatga
    20521 aggcttgaat attggttctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc
    20581 agttgtagaa gcggctgctg ccttgattcg tgaaaccaag gagagcttcc tctaatctaa
    20641 aaggaggtat ttatgacata ctacgttgca attgatatcg gtggaaccaa catcaagtat
    20701 ggtttggttg atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat
    20761 aagggtggac ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa
    20821 ggcccagtag caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag
    20881 attttctatg ctgggccgca aatccctaac tacgcaggca cccagttcaa aaaggaaatc
    20941 gaagaaagct ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct
    21001 gaggcagtat ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaaca
    21061 ggtatcggtg gttgcttgat tatggatagg aaagtcttcc atggttttag caattcagcc
    21121 tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc aagacttggc ttctacaaca
    21181 gctttagtga aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga
    21241 cgtatcttta aggaagccac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg
    21301 gttgactatc taggaaaagg tctggcaaat atttgctacg ttgccaatcc agaagtggtt
    21361 attcttggtg gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc
    21421 ttgaaagagg ctttggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac
    21481 caaaatacag cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt
    21541 ggctcagcca aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt
    21601 attttcccag tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta
    21661 ggcataaatc aaatcgataa agaagagcat aggaagttga gcggatattc gttggatata
    21721 ggagggttgg ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt
    21781 gggaacactt gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc
    21841 taaaatagaa ggagttgagc ctgaaagtga gaagcccagt actagacaat tttcatccat
    21901 gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag
    21961 tcgcataaaa cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa
    22021 gtagatacgc tcagcatctt cgattagctg ggcaattcgc tctagttgga tttcgtcaat
    22081 caagtcttgt gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg
    22141 actgtgcttg gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa
    22201 ttctcggtag ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat
    22261 atgtaatttt tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa
    22321 aaaatagcga gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat
    22381 agttgcgata tctggtttgt ccatagggaa agctccttta catgagtcat actggaagac
    22441 tagatcaggg aatagtcaca cttcattata acacataata taaggataga taaataaaaa
    22501 cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct
    22561 actcaaattg tggtacaatt aagagtaaga ttttaagtta gaaatgagac tgatttgtat
    22621 gagaaaattt aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat
    22681 tttactcttt atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt
    22741 ttacgaaaaa aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg
    22801 ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc
    22861 ctttacgcgt agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact
    22921 gacttatgtg agcatcagtt ctccaaattt gacaaaacgc cagctggcgg attactattt
    22981 ggctgatcct gaaatctata aaaaaacagt ggaagctctc ccaagcgaga aacgcttgga
    23041 ttcagatggc aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtcca
    23101 aacaagtcaa ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt
    23161 aaatgctgtt ggaaactttg cgacaggaac cattgctaca gatcctctaa atgattctca
    23221 ggtggctgtt attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg
    23281 ggatagaaag gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa
    23341 agctggtctc ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga
    23401 ccgtgtagga acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc
    23461 ggtaaaagaa atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga
    23521 aggtagtaag ggaaacaata tcaaactgac cattgatttg gccttccaag atagcgtgga
    23581 tgctttgctg aaaagttatt tcaattctga gctagaaaat ggtggagcca agtattctga
    23641 aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat
    23701 taaacatgac ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt
    23761 ctttgttcca ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt
    23821 cttgtcagga aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat
    23881 caattcttgg tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga
    23941 gtattcatct aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca
    24001 acccaatatg tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac
    24061 ctttggcgaa tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg
    24121 atttgttccc aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga
    24181 taactatacg ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg
    24241 tgtggctcct cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga
    24301 cttgattcag caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat
    24361 gagcatcttg caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg
    24421 acgtgccttt tcaaatggtg ccttggtatc cattagcgga aaaacaggta cagccgaaag
    24481 ctatgtggca gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga
    24541 taatccccaa atcgctgtcg cagtggtctt tcctcataat accaatctaa caaatggtgt
    24601 aggaccttcc attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta
    24661 gaaaggaaat tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt
    24721 taccaggtat cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg
    24781 ctgatgatgt caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt
    24841 gttctatttg tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc
    24901 gtgaccagac aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata
    24961 tccaagaata ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta
    25021 tcagtccgga cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaggttt
    25081 cagaagtgat tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt
    25141 cacgtttgct caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg
    25201 gagcggacat tgagtatgcg gacgaagtga cactcttacg agccattgaa aatcggacag
    25261 agttgtaagt gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga
    25321 aaatcgttcc tatcggcctc tttttgtata gtgtgatgag taggctcagg ttcaagtttt
    25381 aaaaaaccaa gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat
    25441 aatatgaaac aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct
    25501 gtcctttcag ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact
    25561 ttctttatca gtcagtcagg tgactttatc aaaacgcagg aatttagtca tgctccgggg
    25621 caagaagacc gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt
    25681 gctatctacg aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat
    25741 ggctctgttc aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg
    25801 tcatcaagtc ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt
    25861 gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa
    25921 gtggaagaaa aattggttta tccagtcttc actaagccgt caaacatggg gtctagtgtc
    25981 ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga
    26041 tatgacagcc gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc
    26101 ttgggtaact acgatgtcaa gagcacgcta ccaggagaag ttgtcaagga cgttgccttt
    26161 tatgactacg atgccaagta tattgataac aagattacta tggatattcc tgccaaaatc
    26221 agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt
    26281 ggccttggtc tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac
    26341 gagctcaata ccatgccagg tttcacccag tggtctatgt acccactact ttgggacaat
    26401 atggggatca gctacccaaa actaatcgag cgtttggttg accttgccaa ggaaagtttt
    26461 gacaagcgcg aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac
    26521 tgcaaggtga ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa
    26581 caatccatga aattgcccaa gttgttggag tcaaaaatga tatcagtatc tttgaggaca
    26641 cccagttaga aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc
    26701 cacttaaagg tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag
    26761 cagtaacctt gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt
    26821 tgacagcctt tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg
    26881 ctgttacagg ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa
    26941 caagatacaa gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca
    27001 cagttcttca tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact
    27061 tgggagatat tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg
    27121 ttggagaagc tcatttggcc tttttcaaag atcgttctga gattgctaaa ggaaaaatgc
    27181 aaattgcaga cggaatggct tcaggttcct tgcttttaat gccggctgac cctatcgtag
    27241 aggactattt gccaactgat aaaaaggtgg tccgttttgg gcaaggggca gagttggaaa
    27301 tcacagactt ggttgagcgt aaggacagtc tgacctttaa ggctaatttc ttggaacaag
    27361 cccttgattt gccagtgact ggtaagtaca atgctaccaa tgctatgatt gcatcctatg
    27421 ttgccctaca agaaggagtt tcagaggagc aaattcatca ggccttccaa ggtcttgaat
    27481 tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg agcagatatc ctgtcagacg
    27541 tatataatgc caatccaact gctatgaagc tgattttaga gactttctct gccattccag
    27601 ccaatgaagg tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt
    27661 ctattcaact ccataaccag atgattttga gcctttctcc agatgtgctt gataccgtta
    27721 ttttctatgg agaagacatt gctgaattag cccaattggc cagtcaaatg ttcccaattg
    27781 gccacgttta ctacttcaag aaaacagaag accaagacca atttgaagac ctagtcaagc
    27841 aggtcaaaga aagccttggg gctcatgacc aaatcctgct caaaggctct aactctatga
    27901 atctagccaa gttggtagaa agtttagaaa atgaagacaa gtgattttgt caagtatttg
    27961 caaagaatga ttgccattac agatactggc ttaaccttta caaaagatcc gtttgaccgt
    28021 gagcgctacg aagacttgcg agacctttta tctgaaatgt tgaatcaagc atcagacctt
    28081 gattccgaag aagtggcaga agtcttgaag ccaacttctg cttatgcgac tccgttaatg
    28141 gacgtccgtg cttggattgt tgaggacgaa aagatttgtc tggttagggg acaaggagag
    28201 gatagttggg ctttgccagg tggctttggt gaagtcggct attctccaac tgaaaatatt
    28261 ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt
    28321 tttgatacca atcgtttcca actacagagc aaacaatatg caaagtttgt ttttgaatgt
    28381 aagcttctcg atggacaatt ccaagaaaat caagaaatcg ctgaccttca attttttgca
    28441 attgaccaac tgccgaattt atctgaaaaa cgcattacca aggagcaaat cgagattctt
    28501 tggcaggttt atcaaggtca gagggagcaa tatcttgact aagaagatga ttatcgtatt
    28561 tctaaattca tttttcttaa gtagcatggt ataataaaat gcaggaaaat tttgaatcat
    28621 gaggaagact agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc
    28681 aaatttgacc ttttttggta tgttagccta tttacgctct tagccttaac cttttataca
    28741 gcccatcgct atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt
    28801 cagttaatcc ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta
    28861 cccttttacc attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa
    28921 tataaacaat actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca
    28981 gtgccagatg cttacccttt tccacatatc accattctat cctttatctt tggtcattta
    29041 gcactcttgg ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat
    29101 gtgaagggaa tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg
    29161 gtgacaggtg gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta
    29221 gtagctaatt atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa
    29281 atcttagaat tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac
    29341 agagctttct tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct
    29401 gaatagacaa actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt
    29461 ttttgtgtta taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa
    29521 gtgcgaaact tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag
    29581 gtctagatat tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat
    29641 taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg
    29701 atattgatgc agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag
    29761 gcatttcgat taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa
    29821 ctcaggggat gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa
    29881 atgttgtcaa atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta
    29941 ttcctgaaga atttattgtg gatggtttcc aagggattcg tgacccacgt ggcatgatgg
    30001 gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt
    30061 tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag
    30121 caatggttca gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata
    30181 tgggggcagg tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata
    30241 ttctccaaga aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc
    30301 gcaaattagc ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca
    30361 aagaaacctt ccaagtagag gttattggag aagtagaagc agtcgaagtg acggaagcct
    30421 acttgtcaga aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat
    30481 tagatagaag gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca
    30541 ttttaccagg tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg
    30601 ttccaaatca agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat
    30661 ttgcgggtca attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg
    30721 acttaagtca tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac
    30781 aatcaacgcc tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac
    30841 caatggcgga tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg
    30901 gattgatcgg aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt
    30961 gatacagctg ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc
    31021 aatgccatca accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac
    31081 acagatgtac aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa
    31141 ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa
    31201 agcgaagaaa cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt
    31261 atgggaggag gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta
    31321 ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga
    31381 caatttgctg tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc
    31441 tcaaacaaca atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc
    31501 gaagcggata acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca
    31561 ggattgatta accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct
    31621 cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca
    31681 atctattcac cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt
    31741 actggtggtc ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag
    31801 gcagcaggtc aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat
    31861 gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg
    31921 gctccacaag ctagatctgc tactaactac cgtgagacag tgaaaccagc tcattcacat
    31981 ggctttgatc gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt
    32041 cgtttggaac caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt
    32101 gttcgtacaa cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa
    32161 gatgaagatg aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa
    32221 agaaaataca gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctcatcgaga
    32281 gagtggttcg gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc
    32341 cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa
    32401 atatgaagct ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg
    32461 taaggtgaaa gatatcattc aatacgttga ttatttccat gcattggact cagtaaagct
    32521 agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat
    32581 ttctaaagaa gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga
    32641 gttagccaga ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc
    32701 tagcagtgag cagttgaaag agattttcaa ggcggcccaa gatttacaaa gagaaattca
    32761 agagaaacaa attccaaata tgcctatgac tgagttaagt atgggaatga gtcgtgatta
    32821 taaagaagcg attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta
    32881 ggagagaacc atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga
    32941 tgaggattca agtctccctt atgaaaaaag agatgagcct gtgtttactt cagtaaattc
    33001 ttcacaggaa ccggctctcc caatgaatca accttcacag tcggctggga caaaagagaa
    33061 caatattacc agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac
    33121 ggataaggtc attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt
    33181 tgatttattg gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca
    33241 ggctcgtcgt tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa
    33301 aaaggtagct tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga
    33361 tatccgttta ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag
    33421 agtacgataa tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg
    33481 attttggtag ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt
    33541 cgttggattg tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag
    33601 atagcgggtc ttgatttatc tgtttgggtt gcgattgttt tggttcgatt tttaggagaa
    33661 aacctagtgc gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca
    33721 tagaagatcg tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct
    33781 atgctccttt tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg
    33841 ccaaaaccta tggtcttgct tgtagcagta gtggggaatt cgtatcgagt gagtatgttc
    33901 gagttttatt atacccagat tatttccaac cagagttttc agattttgaa atatctctcc
    33961 aggaaattgt gtattccaat aaatttgaat atttaacgca tgctaagatt ttagggacag
    34021 tcatcaatca attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac
    34081 gggcgcagat tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa
    34141 ttggtcgtat acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag
    34201 aacagtatcg agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa
    34261 atgttttgaa actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag
    34321 taaattatca tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg
    34381 tgagaaaatt tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga
    34441 aaaaaataac cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt
    34501 agaaataaag gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga
    34561 tgaattttta gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa
    34621 aaatttgcgt attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc
    34681 attgagccag tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca
    34741 tgaacgttca aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga
    34801 agctaaatat aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc
    34861 tgttgaaaca gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac
    34921 aattgagagt cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac
    34981 agctacttat cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg
    35041 agaaccgatt ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca
    35101 agcagaaatg gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt
    35161 tgaagctcag attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga
    35221 agaagagcct ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg
    35281 catccgacag gtccaacacc agctacagaa actgttgatt cagcaccggg atttgaagca
    35341 ccgcaagaat ctgttacaat tttataagaa atattctgag aacaatatct tatccttata
    35401 ttcccagcga gcaggagatg gtgtgagtcc tgcattccct atcgataaga ttatcctctc
    35461 aaaaactcaa gtctgaatct agtaagattt gacgttcccc acgttacggg ataagaggga
    35521 gaaagactaa aactttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt
    35581 cgtggttttt aatttgttat tatttataaa ggagatacca tgaaactcaa agacaccctt
    35641 aatcttggga aaactgaatt cccaatgcgt gcaggccttc ctaccaaaga gccagtttgg
    35701 caaaaggaat gggaagatgc aaaactttat caacgtcgtc aagaattgaa ccaaggaaaa
    35761 cctcatttca ccttgcatga tggccctcca tacgctaacg gaaatatcca cgttggacat
    35821 gctatgaaca agatttcaaa agatatcatt gttcgttcta agtctatgtc aggattttac
    35881 gcaccattta ttcctggttg ggatactcat ggtctgccaa tcgagcaagt cttgtcaaaa
    35941 caaggtgtca aacgtaaaga aatggacttg gttgagtact tgaaactttg ccgtgagtac
    36001 gctctttctc aagtagataa acaacgtgaa gattttaaac gtttgggtgt ttctggtgac
    36061 tgggaaaatc catatgtgac cttgactcct gactatgaag cagctcaaat tcgtgtattt
    36121 ggtgagatgg ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcatgg
    36181 tcatctgagt cagcacttgc tgaagcagag attgaatacc atgacttggt ttcaacttcc
    36241 ctttactatg ccaacaaggt aaaagatggc aaaggagttc tagatacaga tacttatatc
    36301 gttgtctgga caacgactcc atttaccatc acagcttctc gtggtttgac ggttggtgca
    36361 gatattgatt acgttttggt tcaacctgct ggtgaagctc gtaagtttgt cgttgctgct
    36421 gaattattga ctagcttgtc tgagaaattt ggctgggctg atgttcaagt tttggaaact
    36481 taccgtggcc aagaactcaa ccatatcgta acagaacacc catgggatac agctgtagaa
    36541 gagttggtaa ttcttggtga ccacgttacg actgactctg gtacaggtat tgtccataca
    36601 gcccctggtt ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca
    36661 gtgactgttg atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa
    36721 ttctatgaaa aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa
    36781 gaagaaatct ctcactcata tccatttgac tggcgtacta agaaaccaat catctggcgt
    36841 gcagttccac aatggtttgc ctcagtttct aaattccgtc aagaaatctt ggacgaaatt
    36901 gaaaaagtga aattccactc agaatggggt aaagtccgtc tttacaatat gatccgtgac
    36961 cgtggtgact gggttatctc tcgtcaacgt gcttggggtg ttccacttcc tatcttctac
    37021 gctgaagatg gtacagctat catggtagct gaaactattg aacacgtagc tcaacttttt
    37081 gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga
    37141 tttactcatc caggttcacc aaacggcgag ttcaaaaaag aaactgatat catggacgtt
    37201 tggtttgact caggttcatc atggaatgga gtggtggtaa accgtcctga attgatttac
    37261 ccagccgacc tttacctaga aggttctgac caataccgtg gttggtttaa ctcatcactt
    37321 atcacatctg ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt
    37381 gcccttgatg gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc
    37441 gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca
    37501 agcaatgacg tgcgtatctc tatggatatt ttgagccaag tttctgaaac ttaccgtaag
    37561 attcgtaaca ctcttcgttt cttgattgcc aatacatctg actttaaccc agctcaagat
    37621 acagtcgctt acgatgagct tcgttcagtt gataagtaca tgacgattcg ctttaaccag
    37681 cttgtcaaga ccattcgtga tgcctatgca gactttgaat tcttgacgat ctacaaggcc
    37741 ttggtgaact ttatcaacgt tgacttgtca gccttctacc ttgattttgc caaagatgtt
    37801 gtttacattg aaggtgccaa atcactggaa cgccgtcaaa tgcagactgt cttctatgac
    37861 attcttgtca aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatt
    37921 tggtcatatc ttgagtttga aacagaagac ttcgtccaat tgtcagagtt accagaggct
    37981 caaacttttg ctaatcaaga agaaatcttg gatacatggg cagccttcat ggacttccgt
    38041 ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt
    38101 gaagcacact tgacagttta tccaaatgaa gttgtgaaaa ctctactcga agcagtaaac
    38161 agcaatgtag ctcaactttt gatcgtgtct gagttgacca tcgtagaagg accagctccg
    38221 gaagctgccc ttagcttcga agatgtagcc ttcacagttg aacgtgctac tggtgaagta
    38281 tgtgaccgtt gccgtcgtat cgacccaaca acagcagaac gcagctacca ggcagttatc
    38341 tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt
    38401 gaagagaaat aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa
    38461 ttttatagtc tattaaacgc attgtatcac gtttttgaat acctgatatg atgcgttttt
    38521 tatttatttt aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa
    38581 cttagcaatc taacagtagt aagataaaat aggaatttga ta
//
LOCUS       DAVMBH010000016        37506 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVMBH010000016 DAVMBH010000000
VERSION     DAVMBH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.016"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(117..599)
                     /gene="greA"
                     /locus_tag="VYP30_000931"
     CDS             complement(117..599)
                     /gene="greA"
                     /locus_tag="VYP30_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1807955.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(670..2325)
                     /gene="mltG"
                     /locus_tag="VYP30_000932"
     CDS             complement(670..2325)
                     /gene="mltG"
                     /locus_tag="VYP30_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1807956.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPATPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2406..2900)
                     /locus_tag="VYP30_000933"
     CDS             complement(2406..2900)
                     /locus_tag="VYP30_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807957.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVDLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2897..3361)
                     /locus_tag="VYP30_000934"
     CDS             complement(2897..3361)
                     /locus_tag="VYP30_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807958.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKVIRLESPDELLSYFGMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3371..4705)
                     /locus_tag="VYP30_000935"
     CDS             complement(3371..4705)
                     /locus_tag="VYP30_000935"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1807959.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGSDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4716..5333)
                     /locus_tag="VYP30_000936"
     CDS             complement(4716..5333)
                     /locus_tag="VYP30_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1807960.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSTPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5381..8479)
                     /locus_tag="VYP30_000937"
     CDS             complement(5381..8479)
                     /locus_tag="VYP30_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1807961.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8572..9738)
                     /locus_tag="VYP30_000938"
     CDS             complement(8572..9738)
                     /locus_tag="VYP30_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1807962.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVLLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9746..10840)
                     /locus_tag="VYP30_000939"
     CDS             complement(9746..10840)
                     /locus_tag="VYP30_000939"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1807963.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQTLEG"
     gene            complement(10997..11720)
                     /locus_tag="VYP30_000940"
                     /pseudo
     CDS             complement(10997..11720)
                     /locus_tag="VYP30_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(11745..12680)
                     /locus_tag="VYP30_000941"
                     /pseudo
     CDS             complement(11745..12680)
                     /locus_tag="VYP30_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(12852..14810)
                     /locus_tag="VYP30_000942"
     CDS             complement(12852..14810)
                     /locus_tag="VYP30_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1807964.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(15013..16635)
                     /locus_tag="VYP30_000943"
     CDS             complement(15013..16635)
                     /locus_tag="VYP30_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1807965.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            16741..18186
                     /locus_tag="VYP30_000944"
     CDS             16741..18186
                     /locus_tag="VYP30_000944"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1807966.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(18232..18426)
                     /locus_tag="VYP30_000945"
     CDS             complement(18232..18426)
                     /locus_tag="VYP30_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1807967.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(18527..19122)
                     /locus_tag="VYP30_000946"
                     /pseudo
     CDS             complement(18527..19122)
                     /locus_tag="VYP30_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            complement(19159..19671)
                     /locus_tag="VYP30_000947"
     CDS             complement(19159..19671)
                     /locus_tag="VYP30_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1807968.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERTCRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(19758..20693)
                     /locus_tag="VYP30_000948"
     CDS             complement(19758..20693)
                     /locus_tag="VYP30_000948"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1807969.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(20764..21063)
                     /locus_tag="VYP30_000949"
     CDS             complement(20764..21063)
                     /locus_tag="VYP30_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1807970.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(21053..21802)
                     /locus_tag="VYP30_000950"
     CDS             complement(21053..21802)
                     /locus_tag="VYP30_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1807971.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(21856..22215)
                     /locus_tag="VYP30_000951"
     CDS             complement(21856..22215)
                     /locus_tag="VYP30_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1807972.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(22217..23617)
                     /locus_tag="VYP30_000952"
     CDS             complement(22217..23617)
                     /locus_tag="VYP30_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1807973.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWVKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(23912..24151)
                     /locus_tag="VYP30_000953"
     CDS             complement(23912..24151)
                     /locus_tag="VYP30_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1807974.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(24183..24653)
                     /gene="ssbA"
                     /locus_tag="VYP30_000954"
     CDS             complement(24183..24653)
                     /gene="ssbA"
                     /locus_tag="VYP30_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1807975.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(24665..24955)
                     /locus_tag="VYP30_000955"
     CDS             complement(24665..24955)
                     /locus_tag="VYP30_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1807976.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(25108..26454)
                     /gene="asnS"
                     /locus_tag="VYP30_000956"
     CDS             complement(25108..26454)
                     /gene="asnS"
                     /locus_tag="VYP30_000956"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1807977.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(26470..26835)
                     /locus_tag="VYP30_000957"
     CDS             complement(26470..26835)
                     /locus_tag="VYP30_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1807978.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLVPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGIEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(26828..28015)
                     /locus_tag="VYP30_000958"
     CDS             complement(26828..28015)
                     /locus_tag="VYP30_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1807979.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYSFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(28012..28500)
                     /locus_tag="VYP30_000959"
     CDS             complement(28012..28500)
                     /locus_tag="VYP30_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1807980.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            28821..29369
                     /locus_tag="VYP30_000960"
     CDS             28821..29369
                     /locus_tag="VYP30_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1807981.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKVEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(29607..34976)
                     /locus_tag="VYP30_000961"
     CDS             complement(29607..34976)
                     /locus_tag="VYP30_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682810.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1807982.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASTNEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRTAGSGFRAAGPENKPILNPNNTIAFSDISQGSHSFRGIGHSRGGREIHYDVT
                     TVRRGNNINFTINYFAPGNLREFVNNNFILDKGTGYGEPTPATVITPNLRNQVKNISK
                     GGNFVSHSGYSLEAAVETNKSQTITFSLPITNPNGDLSLRLRPVEFNVDQGGSGTGTS
                     NDPYSNSNYYFETDPLYLDANPNQANPLTTSFNTKVDFQTLYIPTTKLAEGVTELVSE
                     GVEGEKSQAYRLHKFGDQYVLGLPVGNATTVTAAKPRVMKYGIGKIAATQNKTGDTNH
                     IKFYLDKDGDGVFNNQDEVILNTDIKDGERGPTGATGAQGPAGPKGADGQRGPAGPQG
                     PKGEQGNPGTPGKDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTN
                     GQSPTITATRSVQNGKNGVLVTITPVEGRPQTTFVEDGQKGADGKTPTVTITEGQNGT
                     HTLTVHNPGSPDVTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDV
                     YVKNNGNWDKEGNIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDG
                     KDVLNGKANPEAHQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGADGAKGE
                     KGDRGERGLTGAQGAKGADGAAGRDGRDGRDGRDGKDVLNGKVNPEANQGKDGDKYVN
                     TETGDVFVKNNGNWDKEGNIKGSKGDKGERGEDGKTPEVTVTPGKDGHSTDITFTVPG
                     KDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGKYTPGTDEL
                     LGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPLAVIRDGVD
                     GKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQDGQTPTITT
                     QRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRIRRDTDAAA
                     TPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITTKDNGDGTH
                     TITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKETVVKNGKD
                     GKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPDGSHTVTIT
                     NPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETTVRDGKSPT
                     AKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTT
                     TTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNND
                     GTHVVTITNPDGSKTEMVIKDGKDGKCGCQDKPVPPTPNVPTPEVPVKPVPAQPTPNV
                     PTPEVPVQPTPAVSTPEVPVKPVPAQPTPNVPTPEVPVQPTPAVSTPEVPVKPVPAVP
                     EQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVG
                     RRKED"
     gene            35192..36676
                     /locus_tag="VYP30_000962"
     CDS             35192..36676
                     /locus_tag="VYP30_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1807983.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYHFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            complement(36727..37455)
                     /gene="yaaA"
                     /locus_tag="VYP30_000963"
     CDS             complement(36727..37455)
                     /gene="yaaA"
                     /locus_tag="VYP30_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1807984.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
BASE COUNT        10536 a         8364 c         6891 g        11715 t
ORIGIN      
        1 agtaaccata tatacggcaa ggcgacgctg acgtggtttg aagagatttt cgaagagtag
       61 caaaatggaa aaaggagtga gtgaagcaca tcgcctcccc actccttttt ctgtttttag
      121 gctgtttttt caaccttcaa gatttttaca tcatagctac caacaggcgt ttcaattgtt
      181 gctgtgtcac ctgttttctt gccaatcaag gcctgcccaa ttgggctttc atttgaaacc
      241 ttacctgcaa aggcatccgc accagctgaa cctacgataa tataaacttc ttcttcgtcc
      301 tcgccaattt cttggatggt gactgtttta ccaatcgcta cttcgtcctg ggcaactgcg
      361 tcgctattga cgatttcagc atagcggatt tttgtttcta agctagagat ttgtccttcg
      421 acaaaggctt gttcatcctt agctgcttcg tactcactgt tttctgaaag atcaccgtat
      481 gaacgggcaa tcttaatgcg ttctaccact tctggtcgac gaaccaattt caattcttct
      541 aattcttttt caagtttctc cttttcctca agggtcatag gatatgtttt ttctgccatt
      601 tttctcaact ttcttctgat aatattttct aaagaaaatt atgtgaagta tcacataatt
      661 ttagtttgtt tagtttaatt tgctgttgac atgttcagcg acattgcggt cgtggtcttc
      721 ttgattgtta gcatagtaga ccttgccttc tgtgacatct gctacaaagt agaggttatc
      781 gctcttagtt tgattgatgc ttgactcaat cgcatccaga cttggactat cgactggacc
      841 aggcatgaga cctacatttt tataaacatt ataaggtgaa tcaatgttgg tatcaatcgc
      901 aacatcctca gctagactga tattttgccc cagttttcct tgggcataca agattgcaat
      961 attactttga agtggcatat cacgattcaa acgattgtag aatacacctg caatgagctt
     1021 acgatcttct gtcttggcac cttctttttc gaccaaggaa gcaatggtca acaactcatt
     1081 gacagtcaag tttttagatt tgatagtact atagtaagga gataggttct tatccatagc
     1141 agctaacatc tcatcaatca agctctcaat agttgtgctt tccttgatag agtatgtagc
     1201 tgggaaaagg tatccttcca aacgataacg cgcaccgctg tcttttacag gcaaactttc
     1261 cagtaaagta ggatatttcg ctactgcttg actgataaac gtctcatctt gaactttagc
     1321 caagaaagtc tccgctgtca aagactcttt gaagtcacct tgcaattgac ccacagcttg
     1381 agcaatctga tccaaggtat aaccttctgg aattgtcaaa gtcgcaagta caggttcttg
     1441 cggttcatct gttccacctt tttgcaactc tttgagtaag tcttctgtac tcatactctt
     1501 ttgcaaattg tagtaacctg ctttcaagtc ggtataattt ttatacttgg cataaaaact
     1561 aaaaatcaga ccatgcttta ccaaaccagc tttttcaagc gtcgtaccga tttcttgaac
     1621 gtttgaacct tctggaattc caaccgtcac atatttctta gaattagcat cgataggtaa
     1681 caaagaatct agcacgtact ggtaaccaaa gtaaccacct gctgagagca aggcaaggaa
     1741 tacaaggaat gaaatcacaa aagctttcac atgtgacttc ttctctttct taggcttaac
     1801 gggttttgct ccttctctac ggctacgacg tgatgtatcg ctgatgatat ccactgtttc
     1861 tgtagcaggc gtaggtgttg ctggacctgc ttgttctgct tttttctctg ccgtcgtata
     1921 ggaaacagct acccttgttg gggtttcatt gtattctctt tcaagtttct taggtctaac
     1981 aggacctgga cctggtcttg atccactttc ttccgctgga gaagaaggta catcttgact
     2041 tggatgactt ggaacaccag gagtttctct ttgaatctca tctgctggag aagctggtac
     2101 accttgactt gggtgagtag gcacggtagg agcttttctc ataatctcct ctaccgttga
     2161 caaggaatca gccatgagtt cttcagctga aggttcattt gcaggagtgc gaactactgc
     2221 ctcatcttct ttcagaactt catcatagcc ttttactttt tctaaatctc tcagaatctg
     2281 ctctttaaag cttaatttct cttcttctct tgacttttca ctcaaaagtt tttcctcctt
     2341 gttgataatc cataatatta tatcttaaaa gtccaaaaaa agcaatctat gatacttttc
     2401 ctaacttatt ttttcatttc ccagaccata tcataccatg tttcccctgc aaaggttgac
     2461 tgggactggc cttcgttgac aaatccatgt ttttcataat aggcgatgag atagtcatga
     2521 caggttagat taatgccatc tctctcatct tcaagagcaa cttctttcaa ggctgtcagc
     2581 aatttctgac ccagtccgag tccctgtgcc tccttggcaa tagacagaca ggtcacagag
     2641 atataaccac caggctcatg actatagtct tttatttctt ctgtaaaaga ctggtcttgc
     2701 agatggcggt gcaggtcaac tggtccttcg atataaccca tgattcttcc ttctttttca
     2761 gcaaccagaa aagaggtctg aatttctctc aaatgtgctt caaagacaga aggaggaatg
     2821 gcttcttcga ccgaaaaatt ttcaaattca agttcaacaa tccgatccaa atcttctaat
     2881 cttgcttgtc tgattttcat tgttcctcca gataaaaggg attaaaccaa atcatactat
     2941 agccctggct agttgcatag agcaaagttt cttcttcatc aacaaaaccg ttcattccaa
     3001 aataggaaag cagctcatca ggactctcca aacgaatcac tttgtaatcc agctcaactg
     3061 ccacctcttt caaggctgca agaagaagtg ttcccaggcc ctgtctctga tggtcagact
     3121 cgatgactaa agaatgtact tttagacatt gcggattgtc tgactgggga cttgataaaa
     3181 tatagcctaa aagttgattt tcatccctag ctagaagaaa ggtatccgca cacttacgga
     3241 tactttcttc taaaatatgg gaaagttgct gcttttcagc tggaaaagac gaggtctgaa
     3301 gtgcccctat ctcaggcaaa tcagacttgc ttgcctgaat gatcttaatt ggaatttcca
     3361 tgggaacatc ctattgaaca ttgcttgtca agttagacaa gagacgctca aatgagtatt
     3421 cataggtttg gatgtctcct gctcccataa agacgtaaac agcattgtca tggtctagga
     3481 gtggagaaac attttcaaca gtaatcactt ggtgtttttt gttgattttg ttggctaggt
     3541 cttctacctt aacgtcacca tgatctactt cacgagccga gccataaatt tgcgctagat
     3601 aaacagcatc tgcttggttt aaagcatggg caaagtcgtc caacaaggca atggttcttg
     3661 taaaggtatg cggttgaaag actgctacaa tttccttgct tgggtatttc tgacgagccg
     3721 catccaaggt cgcaataatt tctgttggat gatgggcaaa gtcatcaata atcactgtat
     3781 cattgacaat tttctcagtg aaacgacgtt taacaccggc aaatgttttc aagtgctcac
     3841 gcaccaagtt caaatcaaat cctgctgtgt aaagaagacc aataacggct gtcgcattca
     3901 tgatattgtg acgaccaaag gttggaatgt ggaattgccc caagttttgt ccacggaaat
     3961 gaacggtgaa ggttgaacca gttgttgaac gaagaagatc actagctaca aagtcactgc
     4021 cttcagcttc aaaaccataa taataaattg gtgcatcaga cgtaatctta cgcaattcag
     4081 catcttcacc atagacaaaa agacccttgg taatttgttt ggcatagtcg ttaaaggcat
     4141 tgaaaacatc ctcgagactt gtgaaataat ctggatggtc aaagtcaatg ttggtgataa
     4201 tagagtattc tgggtggtaa ggcatgaagt gacgctcata ttcgtcagat tcaaagacaa
     4261 aatatttggc attagccgaa ccacgacctg tcccatctcc aatcaagaag ctggtatctg
     4321 taatgtgaga caagacatga gacaacatac ctgtcgttga agtttttcca tgtgctcctg
     4381 ctactcccat gctaacaaag tcacgcataa agctacctag aaactcatgg taacgtttgt
     4441 agctgatacc attttggtcc gcataggcaa tttcgacgtt gttatctgga cgaaaggcat
     4501 ttccagcgat aatttccata tcaccgtcta gattcttttc atcaaaagga agaatggtaa
     4561 ttcctgcctg ctcaagaccg cgttgggtaa agtagtactt ttcaacatct gatccctgaa
     4621 ccttgtgccc catctggtgc aacatcaagg ccaaggcact catccctgat cccttaattc
     4681 cgataaaatg atatgtcttt gacatgtttt ctcccctatt ctgtcattct ggtcagattc
     4741 aactcttggg caacccgacg ttcttgttct gtttgtttac tttttttatt gtagatttgg
     4801 ctcttcttta gaaaatcata attgtttttc tttggagcag gtgttgacac ttcttcattc
     4861 ttggtaggga tagaatgaac ttcttccgcc aagatataat gagactgggt caatttttgg
     4921 ctatatttga caaattcacc aggattttcc ttttggaaag gagttgtcgg ttgattgccc
     4981 tgtctaacta gactgggctg agaatgacgt ctcgcaaggc tgaaatcctg agttaggtag
     5041 ttagcagagc gtttcttttt caagtccgca cgcgcttctt cacgcgccac ctccgcatag
     5101 ctctttcctt cttttttaac ccctaaagga gcctttttag gtttttcgac ttgcttttca
     5161 atcggtttta ctggtttttc ttcagtaata ggagcccatt ctaaataatt tttatctcga
     5221 tactcaccct tgatattact gatcagatca gactcatcat agagattcat gactggcatt
     5281 tcagtcaaca tgacctcgtc atctgacacc aatggaaatc gttcttgttt cattttctat
     5341 ttcctttcaa cacttcatta tagcgtattg tcttgatttt tcaagtgctg gcttcagaaa
     5401 ttcccaaaat ttctctaatt tctgctaggg tcagactacc acgtgactct gtgccatcca
     5461 atacttgtga caccagatgt ttcttttgtt cttggagttc ctgaattttt tcttcaatgg
     5521 ttcccttggt caccaagcga tagacctcaa ccgtttcttc ctgacccatc cgatgggcac
     5581 ggccaatggc ttgcgcttcc accgcaggat tccaccaaag gtcaaccaag atcactgtat
     5641 ctgcacctgt caggttcaga ccgaccccac cagccttgag ggaaatcaga aaggcatctc
     5701 tttctccttg gttaaaggcc ttggtcatgt cttgtctttc cttggctggg gttgaacccg
     5761 taattttaaa ggatgtcagg cccaagtctg gcagttcttg ttcaattttt tccaacattc
     5821 ccttgaactg agagaaaatc aagacacggt gtccgccgtc tgccacctgt accagtaggt
     5881 ctcggagact atctagtttg ccgctggctc cctgataatc ttccataaac agggcaggag
     5941 tgtcacatat ttgacgcaag cgcatcaaac cagataaaat ttccacacga cttcgctgaa
     6001 attcctgttc tgacacttga gccagatggt ctcgcatctg ttgtaactgg gcaaggtaaa
     6061 tagccttttg ctggtcttcc agttcatttt tataaaccac ctcaatcaag tctggcaatt
     6121 cagtcagaac ttcttctttc ttgcgtcgca tcacgaaagg cttgataaac tgagccactc
     6181 gctctgctgg caatttcata aattctttct tgcttggcaa aagtccgggc atgacgattt
     6241 ggaaaataga ccacaactca cccagatggt tttcaatcgg agttcctgac aaggcaaaga
     6301 ccgacggcac cacaaattgt ctcaaggtct gggcaatctt ggtctgggca tttttcatga
     6361 cctgagcctc atctaagaaa aggaagtcaa aggccatccc ctgataaaac tcactgtcct
     6421 gacggaaggt ggcatagcta gtcacataga tttgatggct ctcggcaaga atctcctcac
     6481 gacttgcttt caaaccatga acaacagcca catccaactg tggggcaaat ttctgaaact
     6541 catctgccca gttgtaaatc aaacctgacg gagcgagaat caaaacccga ctttcttttg
     6601 tcacttgact agtcaaaaaa gcaatggtct gaagggtttt cccaagtccc atatcatcag
     6661 ccaaaatccc accaaaacca taatgatgga gcatctgcaa ccagccaatt cccttttcct
     6721 gataatctcg caagtcagcc tgaacctgag ttgcctgtcg aggaaagtcc tctggatgtg
     6781 tcaaatcctg ggccagattc tggaattctt gtgaaaaaga aacacggtct cgcccttcaa
     6841 agagatgagc taaactgtag gccaaggatt tccgagcctg caaggtccca tcttttaatt
     6901 caaattgccc cagttcctgt agattttggc gaattttctt ggtttcttca tcgaaaaagt
     6961 aaacttgatt agacgaatca atataaaaat cctgattggc aaccaaggcc tgcatggctt
     7021 ggtcgatttc ctcctgggca atatcttgaa aatcaaactg gatttccaag agacctccct
     7081 tggaggcaat ctgcacctga ggactcgcta ggctataaag ctcttctagt ttatctgata
     7141 ggtcaacatg cccgagtttt tcaaagactg gaatgatatc atgaaaaaaa tgatagacag
     7201 actccgcttt taaggcctga cgccaagatt gaaaatcggc ttcaaagccc gcagccaaac
     7261 agacttggaa aattctttct tctaagtccg cgtcacttga aaatggtaat tcttctagct
     7321 cttgtcggct agatacctgt ctatttccat aatcaaactg aatttctaaa cgaatccgat
     7381 tatcttcttc cctgtcaaag taaaaagagg gcgcaaaagt tttgatttgt agacgttctg
     7441 gagctgaaac ggtgcccatc tggataaaaa gagtcagaca ggaggccaat ttgtctcgat
     7501 cactgctatc aaattgcagg tatttctttc cttgttgacc cacaggtaac gctttaattt
     7561 ccttgagaag acgcatctgc tggtctgtta aaaaataaac ctgaccttta tggaaaagta
     7621 ctgctccctg ataaaagaca ttgaccctag gactctcact gatttccatt tcaaaatagt
     7681 ccgagtattc tgttactgta aaggcaaata gattggcatc agcatgcata tcctgaaaaa
     7741 gcagggtttg gtagctatcc acttgatggt caaattgaaa atggggcaag gccatcagta
     7801 aattcacacc ctgctcaaaa aaggtcagag ggaaaaagag gtgccgacct tggttttgga
     7861 aaaagaggtc tgaaaccagc ccttcctccg ttagtccgtg caagaaagtc aaaagttctt
     7921 ggctggcatc atcaaaggct tcccaagaaa gagactcctc ataaatcttg ccaatcatat
     7981 acgactttct ctgctcgaca atccttaaaa aaagtggaat atcccgaatg acatagtatt
     8041 tttggctatt gatttggccg attctcagag tccacaagat atgattggtt cctgcttcca
     8101 cctgacccac agctgataac tcataggcgc attctgattt tggagataaa attcgatcca
     8161 aaaacttgcc acccaaggtc accttggttt caacagcctc tttttcttca tgaccttctt
     8221 ccagactcca caagatttcc tgaccacgct catcattttt cagaaaatgc tctagcgctg
     8281 ccaaatgcac acagtaaccc ctcttttgaa aaaaatcaca ggcacaaaaa accaaatcat
     8341 cctctaaact atagcgcagt tcttcttctg caacgcgagc gtagagccga ttgttctttt
     8401 ccttgatgat atcaacctta ccagtttcat aaagggcaac accttcgata cgaattttcc
     8461 ccggaatcaa tttagccata ttttcacctt taccttatct ttttattata ccatattttc
     8521 gcctatgaaa atagccttct aggaagactt ttctcctaga aggctggatt tttaacgttt
     8581 ggcaaaagta gccacaatcc gctgacagac ttcttgcaac agagatttgg gcatagctat
     8641 attgatgcgg gcatggagac ttccttcctc tccaaaatcc aaaccacggt tgaggataac
     8701 cttggcttca tttctcaaca actcttgcaa tgtttcatca gtcaggtcat aagctgaaaa
     8761 gtcaagccaa atcaagtagg taccttgcgg tttcatgacc ttgattttag tctcttttcc
     8821 aaatagatcc accacataat tgatgtggtc ttcaaagact tgcttgagtt cctctagcca
     8881 atctttaccg tatcgatagg cagcttctgt cgccaaataa cccaagcctg aaatttcatg
     8941 ctgattattg gccaacaggc gtttctggaa agccagtctc aacttaggat tttcaatgac
     9001 tgcataggaa ttttttgttc cagcaatatt aaatgtttta gtggcactgc tcaagacgat
     9061 agcaaaattt ttgaaggcag gattgatggt attgaaagac tggtgtttgt gaccaaagag
     9121 ggtcaaatct tggtgaatct catccgaaac taacaaaaca ccgtgttttt ggcagagttg
     9181 gccaatcttc tccaacactt ctttttccca aacacgtcca ccaggattgt gagggttgca
     9241 aagaacatag agtttaacct cctcttccac caaatccttt tcaagttggt caaagtcaat
     9301 ctcaaacaga ctatcctttt ccactaagga attagtaatc aatctacgat tattcaactt
     9361 gacactgcga gcaaagggtg ggtagacagg cgtgttaatt aaaaccgcct cgccttcttt
     9421 tgtaaaggtt tgaatagctg ttgagatggc tggtaccaca ccctcgataa agacaagagc
     9481 ctctttgtca aagttgtaac cgtattgtgt agcttcccac ttttgaactt ccttaattaa
     9541 gtcttcactg gcataggtat aaccataaac cagttggtct gcgtaagttt gcacggcttg
     9601 gcggatttca ggcaagagca caaagtccat atccgctatc caagctggta gaacttcact
     9661 atccgtttct gtttctttcc atttataggt atggtgccct aaacggttgg gcaggcttgt
     9721 aaaatcatat tttcccatct ttgtcttatc cttctaaggt ttggcgcaaa tctgcaatca
     9781 aatctctagc atcctcaatc ccaatagaca aacgcaagag gtcatctgtc aaaccataag
     9841 aatggcgtac ttctgctgga atatcagcat gagtttgagt cgttggataa gtaataagac
     9901 tttccactcc gcccaaactt tccgcaaaag agaagacctt gagactgttc aaaatatgag
     9961 gaatgcgtgt ttcatcggct actttaaagg aaatcatgcc tccacgacca gtgtagagaa
    10021 cttccttaac tgctggagaa tccttcaaaa aggcaaccac ttcttgggcg ttagctgttg
    10081 agcgctccat acgaagagac aaggtcttga gaccacgaag caactggtag ctgtcaaatg
    10141 gagacaagac tgcccctgtt gtattgagat tgtaaaaaag cttctcgtat agttctaaac
    10201 tattggtcac aaccactcca gccaagacat cattgtggcc tgctagatac ttggttgctg
    10261 aatggagaac gatatctgct ccatcttcaa tcggacgttg gtagataggg ctatagaagg
    10321 tattgtccac caccactttg gcacccttag catgagccaa ttttgctagt ttttcgatat
    10381 caaattccaa catcaaggga ttggttgggg tttcgatata gagaacatcc acatcctttt
    10441 ctaactcggc aatcaactct tcttctgtat tggcataggt aaaatggaaa cgaccttcct
    10501 gctccacttg gttaaaccag cgaaaagaac caccgtaaag atcacgcact gccaagacct
    10561 tacttcctac tggaaagacg ctaaaggcca gtacaatagc tgacatccct gagctagtcg
    10621 ctagggcata gtctgctgac tcaatagccg ccaagacttc ctcagcctta ctacgagttg
    10681 gatttttagt gcgcgtatag tcaaacccag tagatcgacc aaactctgga tgctgatagg
    10741 tcgttgaaaa atgaagcggt gtcaccaatg cacctgtcgc ttcatctgac ttaatacccg
    10801 cctgggccaa aattgtgtta atgtgtaatt ccttgctcat acaatacctc caaatctata
    10861 gtaactattg taccacttat tttcatcaac tcattttctt cttttcaaga gctagttata
    10921 gtttcaaact atataaaaag ggagtttttc ctgctccctt taatagacta taaaatggtg
    10981 aatctcaaaa gacacttcac tctatcattt gctcctgcac aaaacgagca taacgctcat
    11041 gattttccag tagttcctta tgagttcctg agccagtgat tttcccctcc tctaagaaga
    11101 aaatacaatc cacatctttt accgttgaca aacgatgcgc tataatcaca accgtcttct
    11161 cctttaatac agaatagagg ctactgataa tcgcatactc agaatccgca tcaagattag
    11221 cagtggcttc atcaaatata agaatttcag catcttttaa gtaggctcta gctatttgaa
    11281 gtctttggct ttgccccccc tgacaagagt cgtccgcgtt caccaacttc agtatctagt
    11341 ccctctttca tggagcgaat ctcatcacct agtgatacta agtctagcac tttcatcaat
    11401 tcatcatcag ttactaagcg attcaaaccg agacaaagat tgtcacgaat actgccagat
    11461 aagactgcat tattttgtga aacccaagcg attttacttc tccattcttt taagttaaaa
    11521 tcatatatac ttgattgctc cattagaata tctcctgaaa gcggtttata aaactgctct
    11581 aacaaacgca caatcgttga ttttcctgat ccagatggtc caacaaaagc aattttttgc
    11641 cccttgaaaa ttgaacaagt aatatccttt aagacaggtc gattttcatc ataaccaaaa
    11701 tagacatggt taaaattcaa cccttgtcct gataccgatt ttcctcactc aaatttttct
    11761 ttaggaactg caagcaagtt ctccagtgca actgaagatc ccttgctcct agaataaaca
    11821 gttacaaaat tagctatatt actaatagga ttaagtaatt gaaagaggta aatcaaaaac
    11881 gaaaccaagg ttcccacaga tatatatcct gcgctgaccc gataaccccc ataggttagc
    11941 atcacagcta tagccgcaaa gataaataag agagcaaacg aggtctcaaa agaagtaacc
    12001 ctatctgatt tcagtgaatt gttttgtacc ctttcaatac aattatccaa aacatcctgt
    12061 acacttttct ctgcttggtt agtcttaatt aattcatgtt cttgaatctt ttcagtcaat
    12121 tgccctgtta aaaatccgat ttcctcctgt aaacgacgac tatacttttc actgatattg
    12181 gaaaggggca agataataaa catcatacaa ggaagagtga tgaataaaag tagagaaaga
    12241 ttccaatcaa gactaaataa gactacaatg gaaccaagta ccataactaa actcagaata
    12301 atatttggga aagtcgtaat taaaaactca cgaatgacac tcgtgtcatt gacaatggca
    12361 gaagtcaact ccccacttta gctcttatca aagaaggatt tctctgcata aatcaacccc
    12421 tctatcactt ttttcctgat ttttgctatc tttttttcac ccgattgact aaacagatag
    12481 taaccaatag aagaaaacaa ggcttgacca ataaaaatca aaaacgattg aaatactttg
    12541 gaacctatat tttcaataga actcccatct attaaacctt ttaagataag gggaagcaac
    12601 aaagcaagta gactagacag aacaaggaag aaactcccca taatcacctt agtatctact
    12661 cttaataatt ttaatttcat aaatactcct tataatattt caacggataa agtcgggaat
    12721 aactcaattt gaggataaaa tctaataaat cttcctataa caaaacgcat aacatctagg
    12781 attttatata cctgatatta tgcgttttta agcacaaaga cttcttacac aaacttatct
    12841 acaattagat tttatttgac atgttttgcc aattcttctt gggctttttt attggattct
    12901 tctttttctt tcaaccattt ttctctagct tttgcatatt cgtctgttgt gacaatctta
    12961 tcttgtactt tgaggtattt atatgattca atcccttttg taccggttaa accataggca
    13021 gcagcaaatg gtacggttct tctcaatgat ggtgttcccc cacgcgaaac acttggaaga
    13081 actaaagaac tatcaatcaa ccaagcttga atatcagcat atttctcata acgtttggct
    13141 ggatcttgct ctttattagc ttcttccaac atttgagtat agacatccag tccaacttcc
    13201 ttagccttgt cattggcttc tccaggctct agtccaagat tttgtagaac tcctccacta
    13261 ttagtattaa aaatatcgag ataggttgac gggtcttgat aatcaggtcc ccaaccgcca
    13321 tgatataaat catagtcttt ctgagcagct gtttgagcaa agtagcctga actgtcaaac
    13381 tcatctgatg ttaattgctg aatgtcaatc actacattat cagaacctaa aacagattca
    13441 attgattgtt tgatagaact aactccttgt atgcctactt tatctgttac ttccacagtc
    13501 ttatccaagt ggattgggaa ttgaacaccc tttgcttcga gttctttctt agcttccgca
    13561 aacttagcct tggctttctc aggattgtag taagggtctt gaccatccgc aaagttgata
    13621 ccttgccatt ccttaccata gttgaccatc ttagaggcta caacttcacc aaagtctttt
    13681 cccttgatac tgacaaagtt tggaggaacc actaggttac gcaaaatctt tgttgcacct
    13741 tctttccctt cagactgagc cccataagat gttctgtcaa aagcaaaatt gatagcctga
    13801 cggaagtttt tattgagaac tgcttcctga gtcgatttct tttcaatgtc acttgtttta
    13861 gaagtataat tgtaagactt cctatctagg ttaaaattaa agaaatatga agttgaattt
    13921 tgcatactat atatgatatt gtttttgtat ttttctttaa tcccttcata gctggagctg
    13981 ttaggaaaaa gacgagccgt agtataagca ccagctgtaa aattacgttc cagtgattct
    14041 tggtcgctac catcatagta ggtcaatttc acatcgtcta caaagacatt cttagcatcc
    14101 cagtaattag ggtttttctt atattcaata gcagattttg agacaagtgc tttcatcaag
    14161 aaaggtccat tgtacaaaat actagatgga tccgccttcc caaaatcatc cccttttgat
    14221 ttcaggaaat ctgcattaac aggaaaaagt atcgttgcaa gtgtttttga attccagtaa
    14281 agttctggtt taaccaaagt atattgaacc gtttggtcat caagtgcctt gacaccgaca
    14341 gttgaaaagt cgcttgtttt accagtgata tagtcatcca aaccagcaac agagtcctgc
    14401 actagataca aagcttctga ttttttatca gctgcatatt gcaaacctgt cacaaaatcc
    14461 tgggcagtta caggcgcata ttcttctccc tcagaagtaa accacttggc atccttacga
    14521 agtttgtagg tataggtcaa accgtcctga gaaacagtcc aatcctctgc taatgatgga
    14581 ataatattcc catattggtc attttctaat aacccgtcta ccaaatttgc aacaatatcg
    14641 gatgttgctg cgcggttttc tgctagatag ttcaaactag atggatcact tgaataaaca
    14701 tagttatagg tttttgatgc agtgctagaa tttccacacg cgctcaataa aactcctgta
    14761 cccaggacaa gacctgccaa ggttagatat ttgctcttag actttttcat ttccagaacc
    14821 tcctgcttta aatatttgtt ttattataca actctgggtt tgtttagtca attgtttttt
    14881 ccaaaaaatc aaaaaaacct cattttctat ttttgaaaga taattttagc tattttgacg
    14941 ctaaaaaagg aataagtttc aagttctcct aaaagattgt tcaacttatt ccttttattt
    15001 ataaatgcta ccttacgaaa gcttaaattt tgctcgcagg cgatctgctt gggcttttcc
    15061 tattacctta tctaataaat aggtacgcag actcataacc atataaagtc caccccccat
    15121 ggcaccgaca agagctacat aaaagaagct ccacaaacgt ccacttggtt ggaagaaaaa
    15181 tcctaacagc cactggatgg ttcctattaa cagaaacatg actagggtca gcaaactgat
    15241 taaaatggtt cgcttcaaaa tcaccttgcg cttgacacca gttactttac aaatatcccg
    15301 atacatcaag acgttaggaa tgatgagagc aatggttgtt gaaatcaaag gaccataact
    15361 gtggaagagg gcgatggtag gtagttgcaa gactagcttg gcaatagaac catagataaa
    15421 atagagaacg gccttgcggt tgcggaacat ggcctgaagc attggagaca agaccatgta
    15481 caagcctaaa ataatagact gcaaaactgc aaagacaaat aagcccagag ccaaactatc
    15541 tggcttacca tagaagaccg tataaagagg ttctcctacc ataaccactc caaccgttgc
    15601 tggtagcaag aacataaaga gtagggtgag actgtcctga acgagacgag aagctgcttt
    15661 caagtccccc ttgacatagt tttccgtcaa aagtggcaaa ccaacactcc caatcgaaac
    15721 ccctacagaa atcaaaatca tcgtgatttt attaggattg gctgagaaat aagaaaacat
    15781 gacaaccaag tcctcattgc tgtagttggt aaaccagctc atactattga taaaggtcag
    15841 ctgatccaaa atctggaaga gctggatggc agaccctgtc aggataaaag gaatggcttc
    15901 cttaatggta tcaaccaaga gacgcttact gttaatctta tctcctgttt caaagactct
    15961 tttgagtgaa ccttcttggg caaggaaata aatcaagact gcaaaactgg ctaccatacc
    16021 gacaaaggca gcaaaggttg attgggtaac ggctgctaga taatctcctg aaccgagctt
    16081 cataatgata aaggttgcta ggagcatcca gataacacga atgacctgct cagcaatttg
    16141 gctcatagca tagggtttga ggttattcat cccttggaaa aatcctcgga taacactcat
    16201 agacgggaaa atcaagactc cccaagccaa gctttgcatg attgggatca agtctttgcc
    16261 cacgccagac aagtctgcta gccaaggagc aaagacatac aagactaaag caaaaaccag
    16321 gcctagtcct gtcataaagc ctaagaagct ccgaatcagg gcaaagctat gctcttcttc
    16381 tcgcatggta ttatacttgg caacttgctt ggccaccgca actggaatcc ccgctgttga
    16441 aaccaacaag aaccaagcat agatattgta acccatggta aagagaccat ttgccttagc
    16501 tgcataagcc cccatccaga tgtaccaagg gataatgtaa acagccccga gtaggcgact
    16561 gataaagtta ctagccgtta gccaagcagt cccccgtaac atctgggcct gctggtgatt
    16621 gttttcgtgc gacatagatt cctcattcaa ttttgataac taggaaaaac tccttatctt
    16681 ccattataaa cttttccttg ttacttgtaa atttacgact ttcggtttac aatagaaagt
    16741 atgattaaga ttgaaaccgt attagatatt ttaaagaaag atggcctttt tcgcgaaatt
    16801 attgaccaag gtcattacca ctacaactac agcaaagtta tttttgatag catcagctac
    16861 gacagccgaa aagtaacaga agacactctt ttttttgcaa aaggcgctgc ctttaaaaaa
    16921 gaataccttc tttctgctat aacacaaggt ttagcttggt atgtagctga aaaggactac
    16981 gaagtcgata tccctgtcat cattgtgaac gatataaaga aagccatgag tttgattgcc
    17041 atggagttct atggtaatcc acaagagaaa ctcaaactcc ttgcctttac tggtactaag
    17101 ggtaagacaa cagcaaccta tttcgcctat aacatcttat ctcaagggca tagacctgct
    17161 atgttgtcga ccatgaacac aactcttgat ggcgagactt tctttaagtc agcgttgaca
    17221 acccctgaga gtattgacct ctttgacatg atgaatcagg ctgtgcaaaa tgaccgtacc
    17281 cacctcatca tggaagtctc cagtcaagcc tatctagtcc atcgagtcta tggactgacc
    17341 tttgatgtag gagtctttct taacatcact cctgaccata tcggcccgat tgaacaccct
    17401 agctttgaag actatttcta ccacaagcgt ctcttgatgg aaaatagccg agcagtcatc
    17461 attaacagtg acatggacca cttctcagtc ttgaaagaac aggttgaaga tcaagaccat
    17521 gatttctatg gtagccaatt tgataaccaa atcgagaatt ccaaagcctt tagcttttca
    17581 gctacgggta aactcgctgg agattatgat atccaactca ttggcaactt caaccaagaa
    17641 aatgcagttg ctgctggact tgcttgtctc cgtctcggag caagtcttga ggacatcaaa
    17701 aaaggcatcg ctgcaacccg cgttcctggt cgtatggaag tcctcactca gaaaaatgga
    17761 gccaaggtct tcatcgacta tgcccacaat ggggatagtc tgaaaaaact catcaatgtg
    17821 gttgaaactc atcaaaccgg aaagattgct ctggttctgg gatcaacagg aaacaaggga
    17881 gaaagtcgtc gtaaggactt tggcctcctc ctcaatcaac accctgagat tcaagtcttt
    17941 ctgactgctg atgaccctaa ctatgaagac ccaatggcca ttgcagatga aattagtagc
    18001 tacatcaatc atcctgttga aaagattgcg gatcgccaag aagccatcaa ggcggcaatg
    18061 gctatcacaa atcacgaatt agatgcagtt attattgcgg gtaagggagc cgattgttac
    18121 caaatcatcc agggcaagaa agaatcctac ccaggagata cagccgtcgc agaaaattat
    18181 ttataagaat agaaaaaatc aagggaaaat gaaacccttg attttttcct attatttagt
    18241 aaaaacgttt ttcaaacctt caacggcacc ttctacagca ccttttgcgt cttctacaac
    18301 gtcttttgcc ttagcaactg ttttttcaac agctccttca agttctgtct tgctgtctcc
    18361 agtaacttta ccaaaacctt ctttgacagc gcctgttgct tgttccaatt tgttttcaag
    18421 tgacatatga ttgtctcctt tagtttattc cgatatgtgt taccggttac atatagttta
    18481 taccgaatac taaggaaagt caaacaatgt gctcagaaac aagaaatcac gctaagtaga
    18541 aagttaatct ctccttatca aaatcgatag ccaactcata ctttctatct tcattttgca
    18601 caatatagcc taagacaacc aaactgtcca caaagatatc acggcatttc tgcataagct
    18661 ggtctttttt gagaaatttc aacaaaaaag ccgtcatata cttgagtgca tactcaggat
    18721 taacatctcc taaaatgtca tagagctcct gctgtttttc tgtcaaagga tactgctgtt
    18781 tgaccttgta aaaataattg gacagggtca ttttaatgcg cgcaaagtcc gtctttcaac
    18841 taaaatagct gcattgattt gattgcgcaa ttccgtctca aaactctgct ccaacaaggc
    18901 ttgatagacc ggactagctt ctctgacaaa aatctcttga tccagttcaa gactatcaag
    18961 tgattcaagc gtaggaaaat tgaggtaata gcgcttattt tcacgtagaa tcaagcttgc
    19021 ctttatatac tcttccatga gtttatcaac tgcaacatct ggaaattgag ccttaatttc
    19081 ccgtagaatc acatcctcat actggtccag atagcggatc aattctccaa aaatggctgt
    19141 ctcgtcaaac gagatggatt aaaaatctga atcatgaaga ttcctttctt tacattgtaa
    19201 cagaggcgat gctgccaact gactaggatt ggtcccagct tggttcagag gaacaggcag
    19261 acctagttct atgtaatact ccctccaaaa atcactaatc tcctgttccc catctccaaa
    19321 tttcatagga atagtttcaa aaataggtag gatttctgct atatactggg agcagtagaa
    19381 accagctgca tctggataga aagaagcatt gtagggtgct ccaagatgtc tgcaagttct
    19441 ttccttcacc gactggatat ccatttctgg gtaaacatag aggtcgtaca aatgattgga
    19501 ctcaaagaag tctgccggtt cttgacagac aacaccagcc tgtccactag catgataaat
    19561 catcccatcc aaataaatgg caacatggct atagttacct gtggaagtct ggatggcctg
    19621 tcccatgtct gacccatctc tcacaaaaat caaatcgcca ttttctaaca tacttcactc
    19681 ctagaaaaaa aggagccgaa actcctttcg atataaggca aactagactt tccgattttg
    19741 agctgacacc caaaatctta cgcattaaag ctttcagtta attgaggtac cacttgtttc
    19801 ttacgtgaaa cggcaccagc aaggaaggca tgattgtttt caagtttgaa attgaaagcc
    19861 gcttcgacct tgtccatatt ggcaccaaga gccaatattt ctgagtttga gttgacgata
    19921 tctgtaatca tcaagacaaa gtcagagtag ccgtttgatt cgttggcagc ttgcattgca
    19981 gcttcaattt ctgcttggcg ttccaaaact tcagcgatgt caactgtgtt cacttgggca
    20041 acacggacat tatttccgtt gagttcaaaa gtcttagcat cgatgtcaat caattcttca
    20101 gcagatttgc tagccaagtt ggtaccagct ttcaacattg ccaaaccata ttcttccaag
    20161 tttacaccag ccaattcagc caattcagga gcaatgattt tatctgttgg gtgtgttgtt
    20221 ggtgatttca aaagaagggt atctgaaatc aaacctgaaa gcatcaaacc tgcaatctct
    20281 ttaggcacag ctacaccatg ttctttgaac atacggtaaa cgattgaaga cgctgatcca
    20341 actggctcca aacgcatgta aagtgggctt gcagtttcaa agttagccac acggtggtgg
    20401 tctacaacac cgtaaacttc tacttcagcg atatctgata cagattgttg gaattcattg
    20461 tggtcagtca agataacttg ctctgccccc tctgctttgg cagaagtgat aacacgtggt
    20521 gcttccacac caaaatagtt caagacaaag gctgtttctt catttggagt tccaagggca
    20581 acagcttccg tatccaaacc gtaagcttct tttgcaaggt aggcaaaagc tacagatgac
    20641 ccgatggcat ctgagtctgg attttggtga ccaaatacta gaatcttgga catgataata
    20701 cctcattttg tttattttct ttattgtagc atttttttcg ctttttgaca aaggtaagag
    20761 gagtcaaagg actccccacg attcttcaaa ataactgagt aaatttctat cttgattttc
    20821 agataaaaat tcttccttct gtggcctctt cttacgcttg aaaagagctt cagccgacat
    20881 ggcttcttcc ttactggcaa aaccttgagc atagataagt ttgactggca agcgtgctcg
    20941 tgtatatttg gctcccttcc cactattgtg gatagcgagg cgtcttctca tatcagtcgt
    21001 atagcctata tagtaggatc catcacgaca ctccagaacg tacatataag ccttatgatc
    21061 cataataaat ctcttcgatt tcgggcgtat aagagccatc atcattgtgg acaatcaaag
    21121 gaggtaagac cttaaagcca cttgttgagc catccttgat cgcctcaatc aaaagcatat
    21181 tggcttcctt ttctcttttt ggataaacaa actgcaggcg cttaggggct agattatgtc
    21241 gttttaacgt atccaaaata tccagaagtc gatcaggacg atgaaccatg gccaaacgcc
    21301 cattagactt gagaatactc tgggcactat gacagatttc ttccaaatta gtcgtgattt
    21361 cgtgtcgagc caagagataa tgttcactct cgttcagatt agaataagga tccaccttga
    21421 aatagggtgg attacacaaa atcatatcca ccttactccc ctgaatgtga gcaggcatat
    21481 ttttcaaatc atcgcagatg acctgcattt gctcctctaa tccattcaaa cggacagagc
    21541 gttcagccat atccgccaaa cgctcctgaa tctcaacaga caatatctgt gcttgagtac
    21601 gagtgctagc aaaaagcccc actgctccat tcccagcaca gaaatccaca atcaacccct
    21661 tcttaggaaa acgtggaaat cgtgataaga gaacactatc caccgaatag ctaaaaacct
    21721 ctctattttg aatgattttg atatctgtcg aaaagagctg gttaatgcgc tctcctgatt
    21781 ttaataattg ttcttcttcc atggtcctat tatagcaaat ttatattaac attacaaaaa
    21841 atataaaact ctaaactact tcttcttttt taaatggtgc agggcttctc cagtccagat
    21901 tggtagcatt cgtcgaaagg gagcaaaacc gtagttaaag cggtcgcttg aaaagcgtct
    21961 ccgtctagga aactggtact tttcttcctc caaagtgcgg atagaaagac tggctttccc
    22021 cgtaaattca tctaaatcca ctacctgaac ttgaacctct tcatcgactt tcaaggtttc
    22081 atgaatattt tcaataaatc ctgtccgaat ttctgaaatg tgaatcagcc ccgtatcacc
    22141 cgtctctaac tcaacaaagg caccgtaggg ctgaatccct gtaatacgcc cctttagctt
    22201 atcaccgatt ttcatcttag tcctcgattt caatagtttc aattacaaca tcttcaactg
    22261 gcttgtccat agctcctgtc tcaacagcag caatgacatc caagacagcg taagatgctt
    22321 catcagctaa ctgaccaaaa accgtgtgac ggcggtctag gtgaggtgtc ccaccttgat
    22381 tggcatagat ttctgcaatc ggttctggcc aaccaccacg agtaatttct ttcttagaat
    22441 aaggtaggtg ttggttttgc acgataaaga actggctgcc gttggtattt ggaccagcat
    22501 ttgccatgga aagagcacca cggatattgt aaagctcttc tgagaattca tcctcaaaag
    22561 attcgccgta gattgactcg ccacccatac cagttccagt tgggtctcca ccttggatca
    22621 taaagtcctt gataatacgg tggaaaatga caccatcata gtagccatct tttgaaagag
    22681 atacaaagtt agccactgtt ttaggagcat gttcagggaa aagcttgata cgtaagtctc
    22741 cgtgattggt cttaatagtc gcaagaggac cttctactgt ttcaatgtct acttgtggaa
    22801 aatgcaattc tttttctacc ataccaaata cttctaaggc atcaaaaatg ccatcttctt
    22861 ctaatgtttt tgtaatataa tctgcttttt ctttgatttt atcatgagaa attcccatgg
    22921 caacgctgat tccagcataa tcaaagagtt ccaagtcatt gagaccatct ccaaaaacca
    22981 tgaccttctc tggtttcaag ccaaggtgtt ccacaacctt ttccaccccc gtcgctttgg
    23041 agcctgaaat cggcacaata tcagacgaat gttgatgcca acgaaccatg cgaagtttgt
    23101 ctgagagact gtcaggcaag tgcaagtcat ctcccttatc ttcaaaagtc cacatctgat
    23161 agatatcttc tttttcatgg aaatcgggat ctacatctaa gtcgggataa attggattga
    23221 tagcttcact catcatatcg gtgcgagtcg acaacttggc atcatgactc ccaaccaagc
    23281 catactcaat tccttcttgc ttaacccaag agatatactc ctcaacatat gacttttcaa
    23341 tctgatgctg ataaatgacc tgaccttttt tatcttcgat ataagcccca ttcaaagtta
    23401 caaaaaagtc aggtttgaga tcacgaatct ctggaacaac accaaaaatg ccacgtccag
    23461 aggcgattcc tgttaaaatt cctttttcac gcaactgttt aaaaacagtg ggaattgtag
    23521 ttggaataaa ccctgtcttt gaattccgca atgtatcatc aatatcaaaa aagacaatct
    23581 tgatcttctt tgccttgtat cttaatttcg cgtccatctc actacctctt tcaatctaac
    23641 tctttccatt atatcataaa gtaggcaaat cccctatttt caaaaagttt atcattttta
    23701 ttttaatttc ttggatgaga aaaaagacat atttatgaaa aagctccatc gtgcttttaa
    23761 tgtgttctct tgttttcaaa ctcgtaaaaa gggagccact gagcctgact cgctctctca
    23821 tttcaaagct tgtgaaaaaa gacccgttgg ggtcttaatt cgctttcttg ttttcaagct
    23881 catgaaaaag agacccaacc gggtcttttc tttaatcttc gtttacgaaa ggcatcaaag
    23941 ccattacgcg agcgcgtttg atagctgttg ttactttacg ttggttttta gctgaagttc
    24001 ctgttacacg acgaggaagg attttcccac gttctgaaac gaaacggcta agaagctcag
    24061 tatctttgta atcaacatat tcaattttgt ttgctgcgat gtaatcaact tttttacggc
    24121 gtttgaatcc gccacgacgt tgttgagcca tgttttttct cctttataag tttagttgtc
    24181 cattagaatg gtaaatcatc atctgaaata tccaatgggt ttgttgctcc aaatggattt
    24241 tcattacgtg aaaagtctgg tactgaattt gtaggtgctg aatagtttgc agttggtgca
    24301 gagtaagctc cacctgtgtg accctcacgc acactacggc tttccaacat ttggaaattc
    24361 tcagccacga cctctgtcac gtagacacgt tgtccttgct ggttatcgta actacgagtc
    24421 tggatacgac ctgtcacccc gataagtgag ccttttttag cccagttagc aagattttca
    24481 gcctgttggc gccacataac gacattaata aaatcagcct cacgttcacc attttgactc
    24541 ttaaatgtac ggtttactgc aagagtaaaa gtcgcaactg ctacatttga tggggtataa
    24601 cgcaactcag cgtcacgtgt catacgccct acaagtacaa cattgttaat catagtttac
    24661 cttcttacgc gtcaattttg acgatcatgt gacgaagaat gtcagcgttg attttggaaa
    24721 gacggtcaaa ctctttaaga gctgcatcgt catttgcttc aacgttaacg atgtggtaaa
    24781 gtccttcacg gaaatcttgg atttcgtatg caagacgacg tttttcccaa gtttttgatt
    24841 caacaacagt tgcaccgttg tcagtcaaaa tagagtcaaa acgtgctacc aaagcgtttt
    24901 tagcttcttc ttcaatgttt ggacgaatga tataaagaat ttcgtattta gccattgata
    24961 tgttcctcct tttggtctaa tgaccccaag actttgcaag gggtaagtga ggttcgctca
    25021 caataaacta ttatactaga aaaaattttt ttacgcaagt aaaaacacta gaattcgaaa
    25081 aaacgccaca tgggcgtttt cctgttctta tggtttgata cggtgcaaca tacgtgggaa
    25141 tggaatagct tcacggatat gttttgttcc tgctgcgaag gttaccatac gttcgatacc
    25201 gataccaaat cctccgtgtg gaactgtacc gtatttacga aggtcaaggt agaattcata
    25261 ttctgtacga tccatgccaa gttcatccat cttagcgaca agggcatcgt aatcttcctc
    25321 acgcatagac ccaccgataa tttctccata gccttctgga gcaagcaagt ctgcacaaag
    25381 cacgcgctct ggatttccag gaactggttt catgtagaag gccttgatgg ctgctggata
    25441 gttcatgaca aatgttggca caccaaagtg gtttgaaatc caagtttcgt gtggtgaccc
    25501 aaagtcatca ccatgctcaa gatgctcgta gtcagcatct tcatcatttt catgctcttg
    25561 caagaggtca atggcttgat cgtaagtgat acgtttgaat ggctctgcaa tgtagcgttt
    25621 caagagttct gtatcacgtt ccaaggtttc caaggcttga ggcgcgcggt caagaacacc
    25681 ttgtagaaga gctttcacat aagcttcttg caagtcaagc gactcatcat gtgtcaagta
    25741 tgagtactca gcatccatca tccagaactc agtcaagtga cggcgtgttt ttgatttttc
    25801 agcacggaaa actggaccaa agtcaaagac acgaccaaga gccatagccc ctgcttctag
    25861 gtaaagctga cctgattggc tcaagtaggc tggcgttccg aagtagtcag tttcaaagag
    25921 ttctgtagaa tcttctgccg catttcctga aagaattggg ctgtcaaact tcataaaacc
    25981 gttcttgtca aagaactcat aagttgcata gataatagcg ttacggattt gcaacacagc
    26041 tacttgctta cgagagcgta gccacaagtg acggttatcc atcaaaaagt ctgttccgtg
    26101 ttcttttggt gtgattgggt agtcttgaga ttcaccgatc acttcgatgt ctgtgatgtc
    26161 caactcatag ccaaatttag aacgttcgtc ctctttgaca atacctgtca cataaacaga
    26221 cgtttcttgg ctcaagcgtt tgataacatc aaacttctca agtcccactt cttcaccaaa
    26281 tttttcgaca aagtttggtt taaaagccac accttgaaag aaggctgttc catcacgcaa
    26341 ttgtaagaaa gcgatttttc cttttcctga tttgttggca acccaagcgc caatcgtcac
    26401 ttcctgacca acatagtctt ttacgtcaat aatcgttaca cgttttgtca ttatttttcc
    26461 ttttcttttt tattctttat ggcaaaccac ctctatattg ttcccatcca ggtcaatcat
    26521 aaaagcagca tagtaaatcg gatgctcact tcgataacca ggaaccccat tgtctcgccc
    26581 acctgcctct atgccagcct cataacaagc ctgaacttct tccttatttt ctgctaaaaa
    26641 agcaaaatga acaggatctt gtgttccctg agtcagccaa aaatcaccac caggatgagg
    26701 gctgttcggg gatagaaaac taattagaga actagtctta aaagccaatt tatagtccaa
    26761 aggaacgaga aaactcctat aaaatccttc tgaaatttgt aaatccttta ccttaatctc
    26821 aaaatgatca atcattctca ctacccataa atgctttcaa gcgttcgact gcttctttaa
    26881 gcgtgtctag gtctgtcgca tagctgaggc ggacattttc tggtgctcca aatccagctc
    26941 ctgttaccaa ggccacttcg gcttcttcta agataacagt tgtaaagtct gtcacatccg
    27001 tgtagccttt catctccatg gcctttttga catttgggaa gagatagaag gccccttgtg
    27061 gtttgaccac ttcaaatcct ggcacctctg caaggagggg atagatggta ttaagacgtt
    27121 cctcaaaggc ctgacgcatg ctttctacag tatcttgctc acctgataga gcctcaactg
    27181 ctgcatattg ggctactgct gacggattcg aagttgtttg acctgcaatc ttggacatgg
    27241 cagcgataat gtctgcttct ccaacggcat aaccaatccg ccaaccagtc atggcatagg
    27301 ttttagacac accattgatg accactgttt gcttgcgaat cgcttccgat aggctagaaa
    27361 tcggtgtgaa ctcatgacca ttataaacca agcggccata gatatcatct gctaggatga
    27421 gaatatcatt ttctacagcc cagtttccaa ttgccaagag ttcctcacgg gtgtaaatca
    27481 tacctgtggg attagatggc gaattcagca ccaaaacctt ggtcttgtca gtgcgagctg
    27541 cttctaactg ctctacggtc accttaaagt gattgtcttc cttagcagaa acaaagacgg
    27601 gaacgccttc tgccatcttg acctgatctc catagctaac ccagtatggg gttgggatga
    27661 tgacttcatc acctggattg accacagcca taaagaagct atagagagaa tatttggctc
    27721 ccgcagcgac tgtcacttga tttgacgcta cagaatagcc gtaaaagcgc tcaaagtagc
    27781 tattgaccac cgccttaagc tctggcagac ctgaggttac tgtataaaaa gaagcacgcc
    27841 catctcgaat cgatgcaatg gcggcatctt ggatattttt gggagtagtg aaatctggct
    27901 cacccaaggt tagagacaaa atatctctac cctcagcctt cagtgctttg gcacgggctc
    27961 cagcagccaa agtcacactt tcttccattt ctaaaacacg gttggatagt ttcataggcc
    28021 ctccttgttg accaatgctc ctgtttcaaa atctactaga taaaaatcag atcctgactt
    28081 aacttcccag attggcttat cttgataacg gccaaaggtt atcttgtcaa tctcgccagc
    28141 tcccttttcc ttagaaaccg tttctgcttt ttcttgtgaa acaccctgat ttagctgata
    28201 aacgtaaatc ttatggtcat ctttaccaat caggacagca agcgcttctt gctgtttgtt
    28261 acgaccaaga acgctgtaat aagattccaa gccattgtat aaatcaacct gatcagcctg
    28321 ctctaatcct gcatactgct gagctaattt ttctccttca cttttagctg tttgataggg
    28381 tttcatgcta agagaaacca tatacagaaa ggaaccactg ataaccacaa acaaaatcgt
    28441 catccctaga ccatactgcc acagtagatt attttttgct ttgttttgtc tttttttcac
    28501 tcgtctattt taccatctat taagctttat tacaagtgaa tataagaata ctcttcgaaa
    28561 atctcttcaa accacgtcag ctttatctgc aacctcaaag ctgtgctttg agcaaccaat
    28621 tctatttctc ccttcaaaca aaaccgattt tgaaagtgaa acagttctta ctttttcagt
    28681 cacaaatgat tagagtttcc gaaattttac aattttcaaa taaactctga gcaaatttct
    28741 tgcaagttct tttgttttgt tgtaatatat tttataacaa cgagagagtt ctcgaaattt
    28801 taagaaaaag gagacacatc atgtctaaaa aagtattatt tatcgtcgga tcactacgtc
    28861 aaggttcttt caaccaccaa atggcgctcg aagctgagaa agcacttgct ggtaaagtgg
    28921 aagttagcta ccttgattat tcagcccttc ctctcttcag ccaagatttg gaagttccaa
    28981 cacatccagc tgtagctgct gctcgtgaag cagttctcgt tgcggatgct atctggattt
    29041 tctctccagt ctacaacttc tctatccctg gtacagtgaa aaacttgctt gactggctat
    29101 ctcgtgccct tgacttgtct gatacacgtg gcgtttctgc ccttcaagac aagtttgtca
    29161 cagtatcatc tgtagccaat gcagggcacg atcaactttt cgctatctac aaagacctct
    29221 tgccatttat ccgtacacaa ggcgttggtg atttcactgc tgcacgtgtt aatgactctg
    29281 cctgggcaga cggaaaattg gttcttgaag aaacagtcct aaactcactt gaaaaacaag
    29341 ctcaagactt ggtcgaagcg attcagtaaa aaatagaaaa ttttagaaag tctaaatcaa
    29401 ttatagccac ctaatagggt ggctttttat ttctcaatca agattttcag acaaacatca
    29461 gccatccaaa aaaaaccttg agcgttacca ctcaaggttt ttagcagtct tttccatcat
    29521 aggaaaatca ttctaagaat attctttcat tcgagatcta tcacttatca tcttctttcg
    29581 agaaattagt gactgctttt ggctgattaa tcttcttttc ttcgtcctac atataggctc
    29641 aatagaatac cgctacctaa aagaacagag atataatcag attggcttcc agtttcaggt
    29701 aatttgtccc cacggttttc tttacctgta gttggtgcta ctgggttagc atttactgga
    29761 gttgctggtt gagccggtgt tggtactact ggttgttctg gaaccgctgg tactggttta
    29821 accggtactt ctggtgttga aacagctgga gttggttgta ctggcacttc tggtgtcggt
    29881 acatttggtg ttggttgcgc tggtactggt ttaaccggta cttctggtgt tgaaacagct
    29941 ggagttggtt gtactggcac ttctggtgtc ggtacatttg gtgttggttg cgctggcaca
    30001 ggtttaaccg gtacttctgg tgtcggcaca tttggtgttg gaggaactgg tttgtcttgg
    30061 catccacatt ttccatcttt accgtcttta atcaccattt ctgtcttact tccatctgga
    30121 ttagtgattg taacaacgtg agttccatcg ttattatttt taacagttac agttggtgaa
    30181 acgctatctt tgccgtcttt accatctttg ataatagatt tgtattcacg accatcagaa
    30241 tctacgattg ttaatgtatg agttccatct ccgttatcaa cgatgttcgc ttttggtgat
    30301 ttaccatcaa agattgtagt tgtcgttcct ttaccatcag cacctgtcac tttaatagtg
    30361 tgtgaaccat cgttgttatc aataacttca agttttggtt ctctaccatc acgaactgta
    30421 gttgttgtag ttgttccgtc tgagttcaca actgtgatag tgtgagttcc atctccatta
    30481 tccacaacct tagcagttgg tgatttaccg tcacgaactg tggtttcagt tgtcacacct
    30541 tctggatttg taataacgat tgtatgactt ccgtctccat tatcacgaac agatgcggtt
    30601 ggagtacgtc cgtcaacacc gtcacgtcca ttcttaacaa caaactcatt cttagttccg
    30661 tctgggttag tgattgttac tgtgtggctt ccatctggat tttcagtagt tgttgctgtt
    30721 gcagctttac cgtctttacc atctttgatg atagcgttgg taacattgcc gtctccatct
    30781 gtaactttaa cagtatgagt tccatcgttg ttatccgtta cttcaacttt aggagtctta
    30841 ccgtctttac cgtttttaac aacagtttct ttagttgaac catctggatt tgtcaccgta
    30901 attgtgtggc ttccatctgg gttttctgtt gtagtgatat tcgcagtttt accgtcttta
    30961 ccatctttaa caactgttgt tgattcagaa ccatctgggt tttgaactgt gatagtgtga
    31021 gttccatctc cattatcttt tgtagtaata gttggagctg aaccatcacg tccatctata
    31081 ccgttataaa tatctttact atttaatact ttatcgacac cttcgtcgta taccccattg
    31141 tcattaacat catcataaac tgtaacacgg ataccgttac gcgttggagt tgcagcagca
    31201 tctgtatcgc gtctaattct tgaaggtgaa gtaatatctt ctactttgat tttcggtgca
    31261 cggccatctt taccattctt accatctttt acagtgaagg ttactggatc tttacctgat
    31321 gttgtgatag ttacaacagt gctttggcca tcttgtccac gttgagtagt gattgtagga
    31381 gtttgtccat cctgaccggt tgcaccagtt tctcccttag caccatcttg aacaaagact
    31441 gtagttggtt gtgaaccatc atggttatca acagtgattt ctacaccttt atgccctgct
    31501 tcatctttac gaacagctgt aactgtaggt gattttccat ctactccatc tctaattacc
    31561 gcaagtggtt tttctggatt taatggttgt cctgggttag ctggatcttc ttggtaaact
    31621 ttagtttctt taccatcctt gacagtaagc aatgatttac catctcgtcc gtccgcgcct
    31681 ttagcaccat ctttaatcat ttctgaacct agaagttcat cagttcctgg tgtatatttg
    31741 ccgtcattgt tttcatctgt atagaatgtc acaattgtat gagatggatt tccgtttttt
    31801 ccttggacac gaagtaaatc aacttttgga gttttaccgt tcagaccatt ttctccgtcc
    31861 ttaacattta ctgtaactgg atctttacct ggaacagtga atgtaatgtc agtactatgg
    31921 ccatctttac ctggagttac agttacttct ggagtcttac catcttctcc gcgttcacct
    31981 ttgtcaccct tagagccttt gatgttgccc tctttatccc agttgccgtt attcttaacg
    32041 aagacgtcgc ctgtttctgt attaacgtat ttatcgccgt ctttaccttg atttgcttct
    32101 gggttaactt tgccgttcaa cacgtcttta ccgtcacgtc catcacgtcc atcacgtccg
    32161 tcacgacctg ctgctccatc cgcaccttta gctccttgcg ctccagtcag gccgcgttcg
    32221 cctcggtctc ctttttcgcc tttagcacca tctgcacctt tgtcaccttt agggcctttg
    32281 atgttgccct ctttatccca gttgccgtta ttcttaacga agacgtcgcc tgtttctgta
    32341 ttaacgtatt tatcgccgtc tttaccttga tgtgcttctg ggttagcttt gccgttcaac
    32401 acgtctttac cgtcacgtcc atcacgacct actgcgccat ccgcaccttt agctccttgc
    32461 gctccagtta ggccgcgttc gccttggtct cctttttcgc ctttagcacc atctgcacct
    32521 ttgtcacctt tagggccttt gatgttgcct tctttatccc agtttccatt gtttttaaca
    32581 tagacatcac cggtttcggt attaatatat ttatctccat ttttaccttg gtttggttgt
    32641 ggatttactt ttccgtttaa tacatcttta ccatcacgac ctgcttgtcc tgtagctcca
    32701 tcacggatcg tagttgtcac atctggactt cctggattat gaaccgttaa tgtatgtgtg
    32761 ccgttttgcc cctcagttat tgttactgtt ggagttttcc catcagcacc cttttgtcca
    32821 tcctctacaa atgttgtttg tggacgacct tctactggtg taattgttac taatacacca
    32881 tttttgccat tttgcacact tcgtgtcgct gtaattgttg gtgattgtcc attagtaccg
    32941 tttcttccat cagtgatagt tgctaatggt tggtttggat taagtggttg tcctggtcta
    33001 gccggatcct ctacatagac ttttgtttca gttccatttt taacagcaat tagagatttt
    33061 ccatctttac ctggagttcc tggattacct tgttctcctt ttggtccttg tggtcccgct
    33121 ggtcctcttt gtccatctgc tccttttggt cctgctggtc cttgtgcccc agttgcacct
    33181 gttggccctc tttctccatc tttaatatct gtatttaaaa ttacttcatc ttgattatta
    33241 aagacaccat caccatcttt atctaaataa aatttaatgt gattcgtatc ccctgtttta
    33301 ttttgagttg cagcaatttt accaataccg tatttcatta cacgaggttt agcagctgta
    33361 actgtagtag cattccctac aggaagtcct aaaacatact gatctccaaa tttatgaagt
    33421 ctgtatgctt gtgatttctc tccttctacc ccttcagaaa ctaactccgt tactccttct
    33481 gctaatttag tagttggtat atataaagtt tggaaatcaa ctttagtatt aaaacttgtt
    33541 gttaaaggat tagcttgatt tggatttgca tctagataca atggatccgt ttcaaaataa
    33601 tagttagaat tactatatgg atcattacta gtcccagttc cactaccacc ttggtctacg
    33661 ttaaattcaa ctggacgtaa acgaagagat aaatctccgt tagggttagt tataggtaaa
    33721 ctaaacgtaa ttgtttgact tttgtttgtt tctactgcag cttctaaact gtagcctgaa
    33781 tgagaaacaa agtttccacc cttactaatg tttttaactt ggtttcttaa gtttggtgtt
    33841 ataacagtag caggtgtagg ttcaccataa cctgttccct tatctaagat aaagttgtta
    33901 ttaacaaact ctctaagatt tcctggcgca aaataattaa ttgtaaagtt aatattattg
    33961 cctctacgta ctgtcgttac atcataatgg atttcacgac caccacgtga atgtcctata
    34021 ccacgaaatg aatgtgagcc ctgactgatg tcagaaaatg caatagtatt atttggattt
    34081 aagattggtt tattttctgg tccagctgct ctaaaaccac ttcctgctgt tctaaaacca
    34141 ctataccccc tatcaacatc ttccttacgg atagctggat tttggcgagc atcagaaagg
    34201 ctcaaacctg gtttcaagat ttcattagta gatgctggag ctgaagttgt ttctacttta
    34261 gcagctgtgc tagttggcaa aacagcgcta tcaacagctg aacgatcagt tgttgcagct
    34321 ggattagtct cttccttcgc ttcaactata ttagctttct ttgctacagg cgtttctgat
    34381 acagttcctt tgttagagtt agaacgaagt tctagaccaa taatagatga ttgaatagat
    34441 gactctgctg ctgataattc agcttcagat gcatctgctt tcccaagcaa gctttgacca
    34501 gcttggatac ttgtttgcaa gttagcagca cttgcttctg tatataactt gctttctaac
    34561 tttttagcac gcgaaagagc cgttaacaat tttgacttgt caatagcatc ttgatgcgtt
    34621 acttcctctt ttttgtcttt tgcttcttca actttttctg ctggtttagt aacttctcca
    34681 gttttaactg gagtcgtttc tactggatta gctacagttg gagctgcata ggttttctct
    34741 ttattagacg cagaaacctc tgctggttta gtagctgctt ctcccctacc aacagaaata
    34801 ctattggtag tttcttgttt gttttcttcc gcttgtactg tttggacact agctgctgca
    34861 cctaatacca aagcggtacc gagcaagaca ctaactgcac caaagtaata cttacgaata
    34921 gaataacgtt gttgcatgct ataccagtca aatgattttt tatgtgaatg tttcatttta
    34981 aactcctaga tagtatttta tagtttacaa tgtacaacta tttgagacat taatcaatat
    35041 tttctgaaca attaatatat tctgtttttg cacttaaaag ccacttatat tattctaatt
    35101 tttccgatta ctaacgacaa ttttcttgct ctaatttttt tatactactt agacaaaaaa
    35161 agatataatg aattatggag gaaatacccg tatgagaaac cttttatcca caaaagttca
    35221 aagacaatta cgcttaatgg aaaccctaat tcagaatcgt aattggatga aattacatga
    35281 actagccgaa aaattaggat gtacagaacg aatcttaaaa agtgatttaa atgaattacg
    35341 tattgccttt ccatctatta acatccaatc ttctgttaac ggaatcatga tagatttaga
    35401 agttaacact agtgtagaag atatttatca atattttctt gctaattctc aatcttttca
    35461 attactagag tatatgttct tcaatgaggg gctacctatt tatcgaacaa tagaaaatct
    35521 ttactttagt agtgccaacc tctatcgact gggcagaaat attacaaagg ttctttcatc
    35581 tcagtttcaa attgaattat cttttactcc atccgagata cgtggaaatg agatcgatat
    35641 tcgttacttt tttgcccaat acttttctga gcgctatcat ttcctagatt ggccttttcc
    35701 tgaccttcct gaggaagatt taacagagtt tgctgacttc ttctataaaa tcacgaatta
    35761 tccaatgcga ttttcaattt atagaatgta caaactgatg atagctatca gtatccacag
    35821 ggttaaaaat ggtcacttca ttgacctccc caaccacttt tacaaagaat attatcctct
    35881 tttaaagagc attccaaatt tccaggagac acttgcttat ttctctaaac attttgggct
    35941 tgaaatgact ccagatacaa tcgctcaaat ttttatttct tttcttcaga atgatatttt
    36001 cctagatcct caagaattct tcaactcttt agaagataac agtcaagcaa gatactctta
    36061 ccaattactt agtcaaatat tagaacgcct atcaaaacaa tataagatta cttttactaa
    36121 ccacgatgag ctgatttggc atttacacaa cactgctttc tttgaaagac aggaaatctt
    36181 ttctacccca atcttatttg aacaaaaagc attgacgatt aaaaaatttg aagtttactt
    36241 cccagacttt atgggaagtg cgcgtcaaga actggctcaa taccgtcagg caattggaca
    36301 gcatgaccat cctgaacagt tggaacactt gatgtacacc atcttaaccc atgctgaaaa
    36361 cctctctact cagttgttag aaaatcgacc acctatcaag gttttgatta tcagtaactt
    36421 tgaccatgct atatccctta cctttgttga tatgctttcc tattactgta ataaccgctt
    36481 taccttcgat atttgggatg aattaaaaac aagtcctgag attttaaatc agacagatta
    36541 cgatatcatc gtgtctaatt tctatatttc agggattacc aagaagttta tttgccgaaa
    36601 tcatctgtca atcatgaatt tggttaatca tcttaacacc ttatcaaatg agattcattt
    36661 gtccaatact ttataagtta tcaaaaaagt cagcataatc gtgctgactt ttctcttatc
    36721 tgatttctat acttccttta caaaaaccaa tccctgtggt tgtgacaaat cttctcggta
    36781 aacaaatcca gcaaagttca agcgacgtgc ttcccccaca gtttgtactt gattttctat
    36841 taaagctgtt agaaaggccc cgcgcgcttt cttggagata gttgagtgaa tcttcagctg
    36901 accgcctcta tcctccatga atttgaaggt caccatcttt gctctgattt ccttagaaaa
    36961 tacagtctca aactctgatg acaagagaga gaaaatcact tcttccttct tcagagcttc
    37021 atcatagact gccttccaat ggctcttcaa agtcttacca gcgactttta atttcatcaa
    37081 aaaatccaaa cggtgaggag ccatgggtga caaggctgga acaacaccgt acaaagccga
    37141 ggtaatgaag acatgatttt caagataatc ttgttccgcc tcggtcagct tatctctctt
    37201 aatgttgcgg tacataagcc catcaaaaag tttcaaggct ggatagtgtt gagcagtttg
    37261 ccttttcaaa gcttggatat tttgaaattc ttccgccgct ttctcagctg ataccttgta
    37321 gaaactctcc aattgactgg cagaatagag agccaaggca tcaagcacgg tctgactttc
    37381 tggttttaaa ggaattgcct cgatacttgg caagtctgtg ttcatttctt ttgctgttgg
    37441 gattaaaatt ttcatattga tagtgtagca tattttttag ccacaaccaa gaaattcatt
    37501 tgaaaa
//
LOCUS       DAVMBH010000017        35597 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVMBH010000017 DAVMBH010000000
VERSION     DAVMBH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.017"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(358..1965)
                     /locus_tag="VYP30_000964"
     CDS             complement(358..1965)
                     /locus_tag="VYP30_000964"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1807985.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VYP30_000965"
     CDS             complement(2355..2942)
                     /locus_tag="VYP30_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1807986.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VYP30_000966"
     CDS             complement(3070..3519)
                     /locus_tag="VYP30_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1807987.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VYP30_000967"
     CDS             complement(3524..3913)
                     /locus_tag="VYP30_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1807988.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VYP30_000968"
     CDS             complement(3941..4567)
                     /locus_tag="VYP30_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1807989.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VYP30_000969"
     CDS             complement(4581..5144)
                     /locus_tag="VYP30_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1807990.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VYP30_000970"
     CDS             complement(5597..6100)
                     /locus_tag="VYP30_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1807991.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VYP30_000971"
     CDS             complement(6293..7123)
                     /locus_tag="VYP30_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1807992.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDISFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VYP30_000972"
     CDS             complement(7108..8790)
                     /locus_tag="VYP30_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1807993.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8892..9194)
                     /locus_tag="VYP30_000973"
     CDS             complement(8892..9194)
                     /locus_tag="VYP30_000973"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1807994.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9201..9749)
                     /locus_tag="VYP30_000974"
     CDS             complement(9201..9749)
                     /locus_tag="VYP30_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1807995.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9764..10612)
                     /locus_tag="VYP30_000975"
     CDS             complement(9764..10612)
                     /locus_tag="VYP30_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1807996.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10800..12149
                     /gene="trkA"
                     /locus_tag="VYP30_000976"
     CDS             10800..12149
                     /gene="trkA"
                     /locus_tag="VYP30_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1807997.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEHDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            12153..13592
                     /locus_tag="VYP30_000977"
     CDS             12153..13592
                     /locus_tag="VYP30_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1807998.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13718..15397)
                     /locus_tag="VYP30_000978"
     CDS             complement(13718..15397)
                     /locus_tag="VYP30_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1807999.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(15467..16879)
                     /gene="lacG"
                     /locus_tag="VYP30_000979"
     CDS             complement(15467..16879)
                     /gene="lacG"
                     /locus_tag="VYP30_000979"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1808000.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16889..17233)
                     /locus_tag="VYP30_000980"
     CDS             complement(16889..17233)
                     /locus_tag="VYP30_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1808001.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17401..19287)
                     /locus_tag="VYP30_000981"
     CDS             complement(17401..19287)
                     /locus_tag="VYP30_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1808002.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19289..20611)
                     /locus_tag="VYP30_000982"
     CDS             complement(19289..20611)
                     /locus_tag="VYP30_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1808003.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            20779..22002
                     /locus_tag="VYP30_000983"
     CDS             20779..22002
                     /locus_tag="VYP30_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1808004.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            22652..22822
                     /locus_tag="VYP30_000984"
     CDS             22652..22822
                     /locus_tag="VYP30_000984"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808005.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            23435..23719
                     /locus_tag="VYP30_000985"
     CDS             23435..23719
                     /locus_tag="VYP30_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808006.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23712..23950
                     /locus_tag="VYP30_000986"
                     /pseudo
     CDS             23712..23950
                     /locus_tag="VYP30_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24046..24264
                     /locus_tag="VYP30_000987"
     CDS             24046..24264
                     /locus_tag="VYP30_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808007.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(24636..26960)
                     /gene="pflB"
                     /locus_tag="VYP30_000988"
     CDS             complement(24636..26960)
                     /gene="pflB"
                     /locus_tag="VYP30_000988"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1808008.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            27355..28416
                     /gene="dinB"
                     /locus_tag="VYP30_000989"
     CDS             27355..28416
                     /gene="dinB"
                     /locus_tag="VYP30_000989"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1808009.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLRIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(28563..29408)
                     /locus_tag="VYP30_000990"
     CDS             complement(28563..29408)
                     /locus_tag="VYP30_000990"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1808010.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            29664..30532
                     /locus_tag="VYP30_000991"
                     /pseudo
     CDS             29664..30532
                     /locus_tag="VYP30_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(30833..32722)
                     /locus_tag="VYP30_000992"
     CDS             complement(30833..32722)
                     /locus_tag="VYP30_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1808011.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            32860..34425
                     /locus_tag="VYP30_000993"
     CDS             32860..34425
                     /locus_tag="VYP30_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1808012.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            34425..35165
                     /locus_tag="VYP30_000994"
     CDS             34425..35165
                     /locus_tag="VYP30_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808013.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(35274..35489)
                     /locus_tag="VYP30_000995"
     CDS             complement(35274..35489)
                     /locus_tag="VYP30_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808014.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT        11202 a         7622 c         6241 g        10532 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gacccctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tgtgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 agacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca gctaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaatagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcagaatagt caaaggttaa gggggagaaa
     3061 atggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaatga ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgatctgc caataaagtc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tgttgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata tctggccgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggctcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccagcg
     4501 tttcagggta aaatttgacc atgtagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctctca taatgtttta aggttggttt caagagaaca
     4621 tacaacaacc agaatgaaac ggaaaagata acaccttcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaata
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaacttc aagagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aaatcaaagt acatcagcac aaatgagatg
     5101 gctgatagaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaaggg aaagaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagattt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcta aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cctgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaatatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catagcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaga aagacacgtc ctctaattta aagagtgact gcaattctgg
     7921 agtttctttt gccagttcat tctgcagctg aacctgacct tttgagatag acatgttatc
     7981 cagattcgct aactgttctt ccttgactaa gtccacacct aattgacgga gagtcgttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgct tatcaagaca atccgatcca cagggcgatg
     8161 cagaacatcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagcttcgcc
     9001 ttgccgtagg tatggttact gacttcgtca gtttcatcta caacctcaaa accatgtttt
     9061 gagctgactt cgtcagtttc atctacaacc tcaaaaccat gttttgagct gacttcgtca
     9121 gttctatcca caatctcaaa acactgtttt gagcaacctg cggctagctt cctagtttgc
     9181 tctttgattt tcattgagta ttagtccttt ttcaaacttc ctgcacgagt ttgggttcct
     9241 gcataggcaa gtaagagaag agttcctgca atagctacag atacaccatt ggcaattccc
     9301 gcaacaatcc cttgtgcaaa tactttttct gccgcttctt gataaatcac aacatctcca
     9361 agtggtgcca agacacccca aacaagggca tttgcaagta gttgaatgag gttaaaaata
     9421 agaatatctt tccagtcaaa aacaccattg atcactcgaa cgtactttct aaaaagtccc
     9481 acaactagac caaagagtcc gctagcgata atccaagtcc accatagacc ataaccagca
     9541 agagagtcct tgattgcatg accaatcaac ccgacaagca aaccgataat cggtccaaaa
     9601 ataatagaaa gtagcgcttg taccgcatac tgaagctgga tgcttgtatt tggaacaggg
     9661 gttggaatgt tgatcatccc gatgacgaca aagagggcag cgccaattcc gacagcaaca
     9721 acttgtttaa ttgtaaattt gatttccata ctattctcct attttatcct tctattttct
     9781 ttatttcaat ggtccaagat gaaccgacac ctacattata ggccttggca aaggaacctt
     9841 ggttgatagc caaacctaaa cgatagagag agttgatgta aaggatgggt tgcccaattc
     9901 tcacatctgc aaatgatttg ccatagacaa cctgattttg atagaccagc atatcagcat
     9961 gatagatggt cacttcaaaa cgatcaccaa attctggttc cagcttgtaa aattcttccc
    10021 gtgtgataga ggtccaaagc gaaccgaaac gcacatccag aatatcaatg gctcccttca
    10081 ccagatgatc ttctatgatg gtcgctacga ctggaagctc tacaatctgt tccacactga
    10141 gctctggccc tacttcctca aaagtaatgt gaccactggc cagtttagca ccagtatagg
    10201 catagacatc acgaccgtgg aaggtataag aatgctctgt gttttgacgc ctattggcca
    10261 cctcagaaat ctcacgaatg gctacaatgc caacgtgttt cttgataaag gaaagcgtcc
    10321 cattatctgg cgtgacaatg tattgatttt ttgcagtctt ggcaactaca ctcttacgtt
    10381 tcgaaccgac acctggatcg acaaccgata caaacgtcgt tccctcaggc cagtaatcca
    10441 ccgtctgaaa gagacgatag ctcccctcaa aaatattata aggcgtgata tcgtgcgtca
    10501 agtgatggat ttttaaggtt ggagactctt ctaaagccac tccaatcata gccgataccg
    10561 caccatcaac cagaccaaag tctgattgta ataccagtaa attattattc attttatctc
    10621 cttgtatatc ctttatcata ccatatttca gagaaagtcg ctaatagcta tttcaattgg
    10681 ttagggtata gttttacctt atagcgaatt ttcactaaaa gctcttgtta ttagctagta
    10741 ggtgcatttt ttcttgaaaa agggtatgat agttacatca tgaaaaagta ggttttatta
    10801 tgaaaattat ccttgtcgga gggggaaaag ttggttttgc cctctgtcgc tccttggttg
    10861 cagaaaagca tgatgttttg ctgattgagc acgacgaagc tgttctcaat catattgtca
    10921 gtcgctttga tatcattggt atccttggta acggggccga ttttgccatt cttgagcaag
    10981 ccagcgtcca agattgtgat atctttatcg ccctgactga gcacgatgaa gtcaacatga
    11041 ttgcagcagt tctagccaag aaaatgggag ctaaagaaac tatcgttcgg gtgcggaacc
    11101 ctgaatattc taactcttat ttcaaggaaa agaatattct cggtttttct cttatcgtta
    11161 atcctgagct cttggctgcc cgcgctatcg cgaatatcat tgacttcccc aacgccctgt
    11221 ctgtcgaacg ctttgctggt ggacgcgtta gcctcatgga atttgtcgtc aagtccacca
    11281 gcggtctttg ccaaatgccc atttctgatt ttcgtaaaaa atttggtaat gtcattgtct
    11341 gtgcgataga gagggatcat caaattatca ttccaagcgg tgacatgact gtacaggata
    11401 aagatagaat ctttgtcact ggtaaccgtg tcgatatgat actcttccat aattatttta
    11461 aatcacgcgc cgtgaagagc cttctcatcg ttggggcagg tagaattgcc tattatctac
    11521 ttggtattct caaagatagt cgtatcgata caaaagtcat tgaaatcaat cctgaaatcg
    11581 ccagcttctt tagcgagaaa ttcccaaatc tctacatcgt tcaaggagat ggaaccgcaa
    11641 aagatatcct gctggaagaa agtgctcaac actatgatgc cgttgcgact ctaacaggtg
    11701 tcgatgagga aaatctgatt acatctatgt tccttgacag ggtaggtgta cagaaaaata
    11761 ttactaaggt caatcgtacc agtctcctcg agattatcaa tgcgcctgat ttttcaagta
    11821 tcatcacacc taaaagcatc gctgtagata cgattatgca ctttattcgt ggtcgagtta
    11881 atgcccagta ttcagacctt caagccatgc accatctagc caatggccaa attgaaaccc
    11941 tgcaattcca tatcaaggaa gccaataaaa tgactgccaa acctctttct caactgaaat
    12001 tgaaaaaagg ggttcttatt gcagccatta ttcgaaaggg caagactatt ttcccaactg
    12061 gggaggatat gttggaagtt ggagacaagc tcctagtaac aaccttgttg ccaaacatca
    12121 ccaagattta tgacttgatt gcgaggtaag aaatgaataa aagtatgatt cgttacctcc
    12181 tttcaaagtt acttttgatt gaagctgttc tcctcttggt tcctgtggct atcgctgtct
    12241 attaccgtga atcgagccaa gtctttacag ccctcttttc gaccataggg attctcgtat
    12301 tgttaggcgg ttcagggagt ttacagaagc caaaaaatca acggatttat gccaaggagg
    12361 gagtcttgat cgttgccctc tgttggatcc tttggtcttt ctttggtggt ctcccctttg
    12421 tcttttctgg gcaaatccct agcgttattg atgccttttt tgaaattagt tctgggttta
    12481 caactactgg agcaagtatt ttgaacgaca tttcggttct cagccgttcc ctcctcttct
    12541 ggcgaagttt tacccacttg attggaggga tgggagtgct tgtttttgca cttgctatta
    12601 tggacaatgc caaaaatagc cacctagagg tgatgaaggc tgaggttcca ggtcctgttt
    12661 ttggcaaggt tgtatccaaa ctaaaaaaca ctgcccagat tctctatctc ctttatctag
    12721 ctctcttctc cctctttgtc atcatctatt atctagctgg tatgcctctc tacgatagtt
    12781 ttgtcattgc tatggggaca gcgggaactg gaggctttac cgtctataac gacggaattg
    12841 cccactatgg cagctcactg attacctatc tggtcagtat cggagttctg gtttttgggg
    12901 taaatttcaa cctctactac tacctcatgc tccgtcgcat caaggccttc tttggtgacg
    12961 aagaacttcg ggcttacttg gtcattgtac tggtttctac aggcttgatt agcctcaaca
    13021 ccctctacct ctacccaggg ttttcaaaga gctttgaaat gaccttcttc caggtttcca
    13081 acatcattac aacaactggt tttggatatg gagatattac caactggccc ctcttctccc
    13141 agtttatcct ccttttcctc atggcaatcg gtggctctgc tggatcaact gcaggtggac
    13201 tcaagattat tcgaggcctc atcctttcaa aaattgccaa aaaccaaatt ttgtcaatcc
    13261 tatcgcccca ccgtgttttg accctccatg ttaatcaaac ggtgattgac aaagataccc
    13321 agcataagat tctcaagtac tttgtcatct atgctatgat tttgctagcg cttatcttta
    13381 ttgtcagcct agatagcaat gattttctgg tcgtgaccag cgctgtcttt agctgtttca
    13441 ataatatcgg gcctattcta ggaaccactt ctagtttctc aatctttagt cccatctcaa
    13501 aaattctcct atcctttgca atgattgcag ggcgcttgga gatttaccca atcctccttc
    13561 tctttatgaa gagaacttgg tctaagagat aaaatacaaa atccctcttt ttacaattgt
    13621 gaaagaggga ttcttatatt aaaaaagggg gaacgttttt aaatccaagc ctatctgtaa
    13681 gcaaaatctt tactcaaata aaagatggaa aaacttacta cacagcttgg taatgctcca
    13741 atacaaattg taaggcttta cttggactct ttgttaaatg aatatattcc attcctctgg
    13801 tagcaactat ctgaatacct aatctttctg catccacctt catctctcta taataactcc
    13861 gaacttgtgg ggccagaata attaaatcat aaacacccat aatatcataa tgagctccgt
    13921 acgctcctga attcgcaatc actctaactt ctgctaattg agcgccctcg ttaattgcat
    13981 tggctaattg cgcacttgtt ccagaccctg cacaaagaac cagtactttc aactccttac
    14041 tttttattac atctatctca ccaggcatta tttcacttgt atcctcctct aaaataatat
    14101 catttgagct tgcaatatct tctttcacca gtaactgtct atcatacgct ctacagaatg
    14161 gcaaataaat caatatgtcg acaactaaca tcaaagataa aaatacaaag gagataagtt
    14221 gaaaattcgt tccaattaac aatcccaagg gaccaggaaa ggcccaaggt aactggatat
    14281 aaaatccatt cattccaaag aaatcaataa atacctttcc tagaaataca ttcactggtg
    14341 gagtcatcaa aaaagggaca aaaagatagg gattcaaaat aacaggcata ccaaatagaa
    14401 gaggttcatt taccgcaaat aaaacaggag taattgtagc tttacctacc gattttaatt
    14461 gtttagaccg cataaagaaa atcaaaataa atggtacaac aaaggtagcc cccgttcctc
    14521 caatagcagc gatataattc ccgaaattag gtgttaaaga atgataaggg aactgcccat
    14581 ttgcaagaag ttgagcattc tcttccatat tgctcagttg taaagctgta acagcaggta
    14641 agacaataga tggtccatga attccaacaa accaaagcaa agcacacata aaccaaatca
    14701 acatcatagc aggatatgat tctgccccct taaaaatagg agtcaatagt tgttgaaata
    14761 cttgggcaaa aggaacatct aaactaaaac gagatacaat atctaacaaa ccactaataa
    14821 gtaaaacaaa agaaaaagga aaaatatctc taaaagcttg tgatatagcc ccaggaactt
    14881 ccttaggtaa atgaatagta atgtctcgct taatacagaa tcggtaaaca tttacagtaa
    14941 taaaggcact gacaaacgaa gttatcaatc cttgagatcc taaatagttt gtcgacaaac
    15001 ttgtagatcc cgttttctca tcaactacaa gcgttacagt taatacaaga tagccacata
    15061 tggccgccaa cattgcagaa gtatcattta ttacctttcc aggaggcatt tttctattaa
    15121 catttccagc caatgacttt gcaactgtcc ctgaaacaat aatacccaaa actcccatgg
    15181 ttagcatata cactttcctc atccaggcaa tagctggact cggtaactct actccgaaat
    15241 ttttaggaat cataataata atcatcaaaa agcttgaaaa cataattaaa ggcatagtag
    15301 caataaatcc atctttaata gccatcatat aattattagt agaaattttt tcaaatttcc
    15361 cttgttgctt ttcaatggca gcgactaact tatccataaa aactcctcct gtaaaaaatt
    15421 taagctcata gttaaaatat attaaacatc agtcaaatcg ctaaccttaa ttccgtttta
    15481 gcccttttac ccaaagagca cttttcttaa tatatctctt ctgtgtttca taatcaacaa
    15541 agaaaagacc atatcgctta ttgtagccat tcgcccaaga aaattgatct tgcaaagacc
    15601 atataaaata gccttgaata ttgactcctc tatctcgagc ctctaaaact ttgtgtaaat
    15661 gttgctcaat ataacggatt ctcttactgt catcaataat atcattctcg ccctctggct
    15721 taacttcttt aagggctgta ccattttcag ttaaataaat gaccggatgt tgaggatatt
    15781 cttctttgat acgaagcaac atatcaaata acccttgagg ataaatattc caatcccaat
    15841 ctgttgtcgg aataccaggt ttttttacaa attcacctag agcatttaat ttaaaagaag
    15901 actgtccttt tattcctgtt gaattaaatt cttgtctatt ttcacctttg tattcacgaa
    15961 taaattctga acgataataa ttcatcccaa acatcgtatt aagagctgca gctctcttca
    16021 taatttctaa atcaccatct tcaataataa agctagaatt attagcttcc aatatttgat
    16081 tcaagtgaaa aagcgtgtcc tcactgtagt agcccaaaaa agttccatct aatagaaatt
    16141 tattattata aacatcatac cgtttagctg ccaaaatatt ttctttttgc ccatcaatag
    16201 gatagcctgg ctttaaagca tgaatacaac ctacctttcc ctcaatccct aattgatgaa
    16261 attcgaggac tgcaagagca tgcgccaaca acatattatg attcgcttga attgcttcag
    16321 ataattgaaa atgatgattt ggaggaaact gacctcctat atattgacct gcagcaagag
    16381 acatcagttc attgattgta aaccaatgct tgacttctgt aaattcttgg aaacaaaagc
    16441 gagcatatcg tatgaaacga tcaatattct ctctattcaa ccaatcccct gtttctaaca
    16501 ttttctgagg cgaatcaaaa tgatgtaaag aaacaaacgg aatcacatta tgttttaagc
    16561 aagactgaaa gactctatgg taataacgaa cagctaatat attaggctcc ccatctatat
    16621 caggaaatat acgaacccaa gaaatagata aacgcaaagc ctgcaaacca tgttctgccg
    16681 ccaaagctat atcctcttcg taacgataat aaaaatcact agccggatct ggtaagaacg
    16741 gactgttttc ttgcaaataa acatcccaca tatttgttcc tttgccatct accctagttg
    16801 caccctctac ttgataagca gcggtagcag ctcctaataa aaactccttc ggtaaggctt
    16861 taacctgtaa attttccatg actaatcctc attgcaaacc aatatgttct tcaatctttc
    16921 gaattcgttc atattcatca ataaaaaact tgacctgatc atacaatagc atcgttgtca
    16981 tcaaggtatc ttgaccatga atcatgataa aactcacttc aaaattatct ccagatgcct
    17041 cctccgctaa taaattagtc tgttctcgat gggcagacac tattgagtcg tttgcagact
    17101 caaccaattc tcttgcctgt tcaaaatatc catctctcgc aaacgccaaa gcatccatca
    17161 aatctgacct tgcatctcct gcgtaagcga caattgtaaa accaagcata tttatttctt
    17221 cttttgattt catctttctt cctcctcaat cttgatccat cttttacaca tcattattaa
    17281 aatgacttcg ctacgatata aatagaaagt cgaccctaaa tatcttaaaa atccttaaat
    17341 ttcataatat ttaggatcaa tcttctctga ataccttggt tcattttcta tacttatgat
    17401 ttataagtgg aaaccagcgt aattttttgc tacttcaatt acacgataaa catccaaatt
    17461 agattggaat agcagttcgt gcccacggat ataattcaac acatttctcc attcatcttg
    17521 agcttgcctt gtttttccgg ttgcttgaag atataaagcc ttcgccatct taacaacata
    17581 ttcacgatga taactgagct gtttccattc atccttttga ctatttaata acttagaaat
    17641 attttcctca ataattggca aaaaattatc agctagattg taagctatat aataatgatt
    17701 cgctaaaaca tcattttgac gactgccaat tgcattaaaa taatcacatg aggaataact
    17761 ggataatttt tctaaatatt caacaacaga ctgccaattt gacccataca aagcagaaaa
    17821 gtattcttca atcaattctt cataacttct tgtcttcttc cagagcattt cccccataac
    17881 ataattagga aaattatgag ggaatccggc acgtaattct tgacacgaaa tgtaaccgtt
    17941 caaatgtagg ttagaaagat aagatacatc tctgtaaatg gtttgactaa ttttcatata
    18001 gcctaaatcg ccataatgag cacgccctaa aggatagtca tatacgaaac tatctccttt
    18061 aaatgttttt tgccactcaa aaagataaga taaattttcc tcaagagaat tcggaagtat
    18121 aattttatta cgcagataag gtttaggcgt aggtatggaa ttgtcaaaat ctacatctgc
    18181 ataactcatt tcaaatgttc ttgtaatcgg tgcaaacatc atggtaaagc gttcaggatt
    18241 atctaatttt tctttctgag gcgcccatag caactcatgg taaagcagaa aacaaatctt
    18301 tgtatctaat ccctcactcg ttaaagccct atccaattga ttgagaatac gaatatactg
    18361 atccgaaacc aattcttgtc tacagttttc gcattcacaa atattattac gagcatccga
    18421 caaccataca tgtaagtagt taacatcagg tcttttcttg gcataatcct tgataatttc
    18481 taccatctta tcagctacat ctggatttga aaaatccagg ctggttaaaa tcggagccgt
    18541 attaaacaat tctcgtttcc cgtttatttc agcgacatag ggtttcttct cctctgaaat
    18601 actaagacct gattcccagc caaattttga agagtaacct aaaacttcac ctgtccatcc
    18661 atgaccaaca cgatgatgaa taagacctct tttttgcaat tctttatcca acctatcact
    18721 caattcttgt actaattcat ttgaaaattg ttctttattt agatatggat taaattcatg
    18781 ttcataccaa cgtttcaaaa aagagtaagg attttcaaac tggatgaaaa aactgttcat
    18841 cccaatctta ggtagccaat caatgaaatc tagtatattt tcaaatgaat ccgctccctc
    18901 tatacatact cccctatgat agtaactggc tgtttcatct atagatagct gtttatctaa
    18961 aaaatcttca aatcgtaact ctggaacaaa gtcatgtctg cgccctggtc tagtatacac
    19021 aaccccaaat tcatgaaaca ttcggtaaat tccaataagt aaacctacaa ttgtattaga
    19081 ctcaattctt cccttaccct tgtctaatga gataagaaca tggtcttttc tgtcctcttt
    19141 attgactaat cctacaaaaa tatccgcttc cttctcctcg acaagctcta tgttagtctt
    19201 aaagacccga ttcatatagt aacttaattc ctctaaggca aagctagaat aagtattttt
    19261 ctgttgatca aatactctga taaccatctt atttccctcc aacagtagct ttttcttttt
    19321 caagattgcg tttatctgca attttgaaga atggataata aattgctaca gaaaccaaaa
    19381 tcaaaacaac ttgtaataga gctcctcgcc aactagcccc tgttgcaagg aagcctccta
    19441 taatcggtgg cattgtccac ggaaggatta cacctgttgt atagggtact aatcctacag
    19501 ccattgatac ataggtaatc aaggcattga ttgtaggagt agcaataaac ggaatcagca
    19561 taatcggatt taaaactgtt ggaaacgtaa atagaatagc tgtattgata ttaaaaatag
    19621 acggtataat agctagctta cctaatgttt tattcgcacg actcttacta aataggaaga
    19681 gacaaatcgc aagaccaata gtcgctccac cgccaccaat aaatacaaat aaatctttaa
    19741 acggtaatgt aataatgtgt tggagtgttt gtcctgcagc cacagcttct tggttttctg
    19801 tagtaaattg taaccaaact ggatctacaa aagcatttaa aacttgtccc ccattaactc
    19861 cacagaacca aaagaatgag tttacaataa cacatagaat catacctgga agcgttcctg
    19921 caattaactt aagcggtgtt ccaacaattg cacctaggag tccgttgaga cctcctgcaa
    19981 ctcctgccgc ttcaagacct tttaagacca aagcccacaa aacaaaagta gtaaagccag
    20041 gtaaaagagc tgaaaatgat ttacttacca catctgggac accacttggc atttttatcg
    20101 taattccgcg ctggataaac atacgataaa tctctgctgt aaccaatcca atagtaatcg
    20161 ccataaacaa agaagatgca ttcaggctag aaaatggtat tgcgccgcca aataactgct
    20221 tgacctgctc cccattttta tcataaacca tactcgaaaa acgaggtgcc atcaatacaa
    20281 aactggataa ggctatgatc cctgccgacg gaccatctgt accatatcct tccgacaacc
    20341 tgtaggcaat accgaaacaa gcgaccaagg agataatcgc tactgttgac tgattcatag
    20401 ttgtcaagat acttagcaat ccaacactat tcagccaatt tgtaaaatcc tcttgaggcc
    20461 aactgattag aataagaaat aaagatccga ctaaaatcaa aggcattgcc atcataaatc
    20521 cttcacgaat agctttcaaa tgccgttggt tgccaacttt ttcaccaaac ggagcgactt
    20581 ttgtttctaa aaacgctaaa atattgttca tcaccggaac tccttttttt attttttata
    20641 aattaaatat accactaaca gaaagcgttg tcaatatatt ttttgttgtt tttacaatat
    20701 ttttttcttt gtatagaata ataattttaa ttgatttttt cttatgttta atataaaata
    20761 aaccaaagga ggaaacaaat gattacaaaa caatcagcct ttttacaaaa tagagccact
    20821 atactggagt ttctatatcg aaatccagca acatcccgta cagatattgt taatgaaaca
    20881 ggacttactc cagcaacaac gactaacatc ataaaagagc taagcgaaca gtccctcata
    20941 tacgaaactg gtgatgaatt tagcgagttt tccggatctg gaagacgtag aaaaactatt
    21001 tctatcacag ataatattcc gtatgttgtt ggaggtattg aaataaacgt cctaggtatc
    21061 tttctcagtc tatgtgactt acaagggaaa actcttttcg agacagaaat tttgaatgaa
    21121 gattatccta tttcagaaat caattccacc attaccaata tgataaaaac agctatagag
    21181 tacgtccctt tggaaacaaa attacttgga tttggcttat caatacctgg acattataac
    21241 aaagactccg gaagtatcat tacaaacaac cccatatggg aatcttttaa tttattaaat
    21301 gtaattaaaa gattcaattt tccttttatt gtaaaaaata atatcgattg tatggctata
    21361 ggacaatacc tttttaatcc acacaatacc cccgataact ttattttcct acacgctgga
    21421 ttaggtattt acacttcctt tttcacaaaa gaaaaaatag gagcctctaa aaatccttat
    21481 atcggagaaa ttggacacac cattgtcgaa ttgaatgggc aatattgtga atgcggaaaa
    21541 aaaggttgtt tacaaacata tatttcggat gcttggttaa tcaaacacgc ccaattatta
    21601 tttaaaaatt cccaactaac tgtactaaaa agccttgtaa agactgaaaa agacattcat
    21661 ttagacaccc ttttaacggc ttataattta ggcgactccg ctttacgtca acaaattgat
    21721 aaaggagtca atttattagc cacttctatt gcaaatctcc tcctcatcaa tcctgctgat
    21781 aaaatctata tcaacagtca attgcttaat tatcaacctt tcactcatga agtcagggat
    21841 aaaatccaag accagctcca cttcgttccc tttactcgta atatagaaat tgaaatttta
    21901 ccttacaaca aacatcgtgg aagtatagga gcttgtgcat tagctatcgt cgcttttttc
    21961 atagaacata gcaatgtatt acaagatatt atttcacctt aatatattag aaatctatag
    22021 acctgtttaa atcaactata acctgtagta gatatctcgt atttagacaa tatgaaaaca
    22081 agacgacttc catataggaa accgccttct ctctatgttg agtgatttat attaaaataa
    22141 cttttcttct agctgcattt tattattata aaaacattca tcataaccct gaacttaaat
    22201 aacgattttt attcaagata catactccta gaataaactt tatatgaaat tctcattttt
    22261 gtttttacaa ttctccttag ttaaatcttg tttaatatat gttttacata tagtatttag
    22321 cgccacatag tactgaactc tctccaaaaa cggttattcc tctttgaata gggcgttatc
    22381 acaagaaaag catctccacg tttcaacttc atatggctca aaaacaatca attgatgcta
    22441 aaacctgtac ctagatgttt cggttcataa aaccatgaaa ctgtaaaagt ggatgaaatt
    22501 gatagcgata gtcaaatcaa gaggcatcat aactctaaaa agtcacaata tataagttca
    22561 tcctcggaaa aatatcattc taattgttga aatgcctaca tgaaaagaaa cgtcaaatgc
    22621 tcatgaaaca acgaatacag gtatcaaaac tatgacaaaa caagtcccta aatttactaa
    22681 agacactgct caactttaca cctgtaaatg gttgttgtat aataaagtta caaagatgta
    22741 cgaccacact gttgtaaatc atagtgttcg cgaatatatt actgatagca tttctacaaa
    22801 tacaattgaa gagactggat aggctttaaa cgaaatatgt cagtgttttg gcattcctag
    22861 tcttcatatc atttaaagaa ttgtatagac aaaatttttt tccaatacag acactcgtaa
    22921 caactgcttc atttttctac caacatattt aggaacagga taagatagaa gaagattaat
    22981 ccatagctca gttctatacc aatctaagac aaataagcta aaaaaacgat tgataataag
    23041 caaatagatt ccaaattttc tctatctgct cattttaata aacaatacta gtgtaactat
    23101 ccttccagtc agaaacttgt caaatcacac cgaaaactct tctaaaattt atctcgttag
    23161 gcaatcaagc aaaaactcga cgatagtaca aacattatca tacagaattg actgcctaaa
    23221 ttatatactt tagtaaggtt ttcggataag aaaaaaggtt cattttacat ttctaaacat
    23281 tcttttctaa gatgaaaaac agaatttttc gattgtgatt taaagcaaca agaagatttt
    23341 cagtatcatc ctatagatac gagctaatta agaaaaacta catttttgaa tataaactac
    23401 aataatataa actaaatttt ataggaggaa gacaatggat tggtacgatt atatgataca
    23461 ggcatccaaa caatcacaat tcaacgcaag ccattggttt cgctatttgc gaaaagttat
    23521 ttttgaagac tattcttatt taacaaacca agatgtagaa aagttgctag actccaaaga
    23581 actaacccgt tttcaaaaaa ttagcttgaa gtatgccttt caagagcata ctccaactca
    23641 taaatatgtg atttcattaa ataaacctgc taagttaacc aatgttcaaa aattgatgga
    23701 gaaatacaaa catggataaa atgaaaccgg tcttccaagc cctaaataag aaattaattc
    23761 aggaaaatct gactttaaca attatggtta tgtcttagaa tatcatggtt tacgtgccac
    23821 acaagatgtt gatgcttttt atgaccaaaa tcagaaaatc aatgaaatta ttgctcgtgt
    23881 aggaaaacag tttaatctta acatccacga agagttatgg ctcaacaatc atgttgcaaa
    23941 gcaaatatga acaaacaacc tcccttaagt ttatgcgaat ccttgtactc atttgagaat
    24001 ctgaccgttt tagtagtccc tattgagtat gtgttaggaa tgaagatgat gagtatcaga
    24061 gagcaggatt tgcaagatat tggtgcaatt attaaataca aaaactttca ttcaccattc
    24121 gataccttta aatatttaaa agacatggga tttgatacta ttgacctctc tgttctatta
    24181 gaaggtttta gttatgctta tggtatggat tggttagaaa aattttttaa agaaaatcaa
    24241 gataaacttc gcgaatttta ttaacagtat caaacaagat gattgtcaat tagccagtcg
    24301 tcttattttt atgatgaaat gaaatgaaat aaaatcggaa caaatcactt agagaattcc
    24361 agtcaatttc tagcactgtt tgagccgttt cagcggacta tagtaaaatg aaataagaat
    24421 aggacaaatc gatcaggaca gtcaaatcga tttctaagaa tgttttagaa gtaaaggtgt
    24481 actattctag tttcaatcta ttatatttca gattcggtcc actgttcctt cccaaaaaca
    24541 ttgcatattg cgccgaagga attgctcaca ctatcccaag cacaaaaccc tcagtcgatt
    24601 gaccgagggt tccttttcat tattcaaaaa cttgattagc tcaatgcatc caaggcatca
    24661 tccattgaaa gaacttcgtg gaagacacgt tgtgtcaatt cagttttttg ttctggagtg
    24721 aggtatttag tatttacaca gtatccagag atacgtacga taacgtcttc acctgacatg
    24781 attttttcgt aaacatcgtt caagtccata acgttcaagt taacgtgttg tccaccgttt
    24841 tcgaagtaac catcaaggat tgttaccaag ttatcaactt gttcatcacg agtcttacca
    24901 agagcgcgag gtgatacttg tgtagtcaat gagataccgt cagctgcata actaaagtca
    24961 aggctagaaa gtgagttcaa gttttgcaac caaccacctt tagctttgtt agatgggtta
    25021 gcacctggtg agaagaattc aagtttagac aagttcacag aaccatcttc gttgaggtat
    25081 acacctttgt gaactggtga gttaccagtt tgtttagagt aagcaacgtt agatgtgatt
    25141 gtcaaaagtg atactgtagc ttctgcgtct ttgtatagtt tgtggctacg tagacgagtt
    25201 gtgtaagctt cgatcaacca ttctgccaat tcgtttgaac gtgggtcatc ttcaccccag
    25261 cgtgggtagt caccgattgt ttcgtaatcg tagatgtagc catcttcgtc acggattggt
    25321 ttaactgtag cgtatttgat agctgacaat gtatcaacag tgttagcaaa tccacagata
    25381 ccgaatccca tgttcgcacg ttgtttagtt ggcaagaagg ccatttgaac agcttcgtag
    25441 ttgtacctat cagtcatgta gtggatgatg ttcaaggcat ctacgtaagt gtcagtcaac
    25501 cagtcaagag atttttcaaa gttcgcttta actgattcaa attcaagaac ttcgtcacgg
    25561 attggttcga tatcaaatac tttgtagtct ttgtgaacat cgtcgtaacc accattcaaa
    25621 ccagtaagaa gggctttaag aacgtttaca cgagcaccga agtactggat gttgtggcgt
    25681 tgttcttcat tttctggatc aagtggagac acacagcatg agatacagct catttcacca
    25741 tatccgtctt tagccattgt tgttacacct tcgtattgga tagaagagtg tttgtggctc
    25801 atgtgcatac agtagcgacg gaagttgtat ggcaatttgt cagtccaaag aactgtcaag
    25861 tttggttctg gtgagttacc gatgttgtca agagtgttca agaaacggta gtccatctta
    25921 gtaacacggt gacgaccgtc gttacccata ccagccatag aagttgtgat aaaggttggg
    25981 tcacctgagt acaattggtc ataagctttg gtacgagcaa atttaactgt acgaagtttc
    26041 ataacgaaat catcaacgaa ttcttggatt tctgattcag taaatgtacc acgagcaagg
    26101 tcacgttctg caaagatgtc caatacgatt ggtacacgac ctagagatgt agcagcaccg
    26161 ttaatcacac ggcagacagc catgaaagca atgttaaccc attggattgc ttctttcacg
    26221 ttcatcgctg gtttgcgaac atcaaccccg taaaggtcac ccaggcgaac aacttgttgc
    26281 aatgcttggt attgaaggtt tacttcttca cgaagacgga ttgtttcttc atcgatttct
    26341 ttgattgcat tccagtcgtt tactttttct tgcatcaagt agtctgcacc gtaaagagca
    26401 agacgtgcgt aaacaccgat gatacgtccg cgtgagtatg catctggaag accagttaca
    26461 gtgtgtgcat gacgagcgcg acgaatattt gaagtgtagg cacggaaaat accgtcgtta
    26521 actgttgtta catatttagt gaagatttcg tgaacagctg ggtctggttc gtatccattt
    26581 tcttttaaag tagtttcagc catacggata ccaccttttg gcatgaagtt caatttgaag
    26641 agttcatcat tttggatacc aaagataact tcattttctt tgtcgataaa tccagcaggg
    26701 atatcagcga tagatgttgg acgagtgtcc attgggaaac gagtttcttc gtagtgtgct
    26761 ttagtttctt ctacaatttt cttgatgtga agtgaacgct ctgttggtcc tgcaaggaag
    26821 ctttcgtctc catcataagg tgtgtagtta gcttgtacaa agcgtgatac acttgctttt
    26881 tctttccaat ctacgccttt gaagccttcc caagctttgt caaaaatatc ttgtgcttca
    26941 acaactgtct taacaaccat attaatgtcc tcttttttct agtaacagtc atctgttaca
    27001 ttcataagac aagtatacca taaagtaacc gatttcaaca agtgcaaaat ccctattttt
    27061 acactttctt ttctaaaaca gtctatattt tatttcaaac tgtattatat ttttgaaaaa
    27121 aataaagtcc ttttttcttt ttttcagaaa aaagggtata ataaaagaaa ataagcagta
    27181 acactcaatg gaaatcgaaa agcaaactag gaagctagcc gcaggctgct caaagcactg
    27241 ctttgaggtt gtaaatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgcaga
    27301 tggaagctga cgtggtttga agagattttc gaagagtata aaaaggtgct aggcatgttg
    27361 atttttcctt tgttaaatga tttgtcaaga aaaatcatcc atattgacat ggatgccttt
    27421 tttgctgcag tggaaatcag ggataatcct aaactcagag gaaaacctgt cattattgga
    27481 agcgaccctc ggcaaacagg tggacgggga gtcgtttcta cctgtagtta tgaggcaaga
    27541 gcttttggtg tccattctgc catgagttcc aaggaagctt atgaacgttg tccccaggct
    27601 gtctttatct cagggaatta tgagaaatac aagtctgtgg gactccggat tcgagctatt
    27661 tttaagcgct atacagattt gattgaaccc atgagtattg acgaagccta tttggatgtg
    27721 acagaaaata aactcggtat caagtcagcg gtcaaaattg ctcgcctcat tcaaaaagat
    27781 atctggcaag aactccatct aactgcttct gccggtattt cctataacaa gttcttagct
    27841 aaaatggcga gtgattatca aaaacctcat ggtttgacag tgattctacc tgaacaggct
    27901 gaggattttc tcaaacaaat ggatatttcc aaatttcatg gagtaggaaa aaagacagta
    27961 gaacgtcttc atcaaatggg tgtttttact ggtgctgatt tacttgaagt tcctgaggtg
    28021 accctaatag accgttttgg tagactaggc tatgatctgt atcgaaaggc tcgtggcatt
    28081 cacaactctc cagtcaaatc caatcgcatc cgtaaatcaa tcggcaagga gaaaacctac
    28141 gggaagattc tccgtgctga ggaagatatc aaaaaagagc tgactcttct atcagaaaaa
    28201 gtcgctctca atctacatca acaagaaaaa gctggaaaaa ttgtcatttt gaaaatccgc
    28261 tacgaggact tttcaactct taccaaacga aaaagtattg ctcaaaaaac acaagatgct
    28321 agtcagataa gccaaatagc cctgcaactc tatgaagaat taagtgagaa agaaagaggt
    28381 gtccgcctat tggggattac catgactgga ttttaaagct caatgaaaat caaagagcaa
    28441 actaggaggc tagccgcagg ctgctcaaaa cactgttttg aggttgcaga taaagctgac
    28501 gcggtttgaa gagattttct aagagtataa aaccttgaag agttgcccct tcaaggtttt
    28561 tcttatacaa ataaacggac aaaactgtaa agtagcaaaa cactaccaag cacgatacgg
    28621 tatttaccaa aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc
    28681 accatgctga ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag
    28741 ctcaagagtt ctccggcttt cacaaatttg aaaatcttta aggcactagc tccaaacata
    28801 acgggaatcc caagatagaa ggtaaattct gtcacaactg aacgactggt tccatttaac
    28861 aaaccaccga caatcgttgc acctgaacgg ctagtccctg gtaaaagagc aagaacttgg
    28921 aagagtccga tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt tacacttggc
    28981 tcgatagcac gcgctttatt gcgcttttcc aaatagatga aggcaacccc gtagataatc
    29041 aacatgagag caactgaaac catgttatgg aagtgggtat caaaccaatc atcaaattta
    29101 aagacaccaa gtaaaggcaa agtggcaatc aagaccttca accatagtct ccaagtctta
    29161 cgaacttcct gtttgtcctt agtcggttta aaaggattga gcttgttaaa ataaatcacc
    29221 ataactgcta aaatagcacc aagctgaatc acgacattaa acatggacat aaaggcttca
    29281 ttttgatttt ggtattggat aaactcctct gctaaaatca agtgacctgt actggaaatc
    29341 ggcaaccatt ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa aatttcaata
    29401 agatacatat atttctcctt atattatatt taacgcagtt agctactgcc aaagcccaag
    29461 tggtatactt ggaataagcc actgtggatt agttcatttc ctccaatcgc ttgacgattt
    29521 ccgaaaggct ctaaccacag ctttttgttt caattggtaa tgagtttgat aacgcataga
    29581 cgttttatct cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag tagacttgaa
    29641 atactatatc tggaggtact cccatgcttt atgtgggcat tgatgtcgct aaaaataaac
    29701 acgatgttac agccttgaat gttcgaggaa aactgttctt aaaccactca ctttttcaaa
    29761 taataaagct ggttttgaac tcttagatct gtcttttcga cagctcaacc aagactgtct
    29821 catcgctctt aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca
    29881 agtagaacta aaaatactgg ctagacatat tcatcgtctc aagaaaaaac agtctgattg
    29941 gaaagtacaa tacactcgtt gtcttgatat catctttcct gagttggata aaatcgttgg
    30001 aaagcattca gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggct
    30061 tgaggcaaga tttgataagc tgatagaaat taagcgattg accgcttcta aaattcagaa
    30121 tatcctctca gtcgcacctc gttctatcgg aacaacatct cctgctcgtg aattcgaaat
    30181 catcgaaatc atcaaacatt acaagaggct cattgacaag gcggaaacat gtgtcaatga
    30241 cttgatggct gagttcaact cggccatcac gacggttact gggattgggg gtcgtttagg
    30301 ggcggtcatt ttagccgaga ttcgaaatat tcatgccttt gataatcctg ctcaattaca
    30361 agctttcgct ggactggatt cttctattta tcagtcaggt cagattgatt tagctggaag
    30421 aatggtcaaa cggggttccc ctcatctgcg gtgggcactc atacaagctg ccaaagcatg
    30481 cgctcgcttt tcacctgctt ttaaggccta tcttaagact aagttagaat aaggaaaaca
    30541 ttacaatgta gccatcatcc accttgcaaa aaaacttatc cgaaccctgt tttatatcct
    30601 aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat ttctgaaatt aacacaggat
    30661 tacctttgaa aaaatggact ttttcaaggg ctttttgccg tgctctaaaa tcatcgccaa
    30721 atcatcaaat tgaaataaga aatagtttag ataaaactat tgacttttct tatagtttgt
    30781 ctttcttcta tcttccatta tatcatactt tttcagtcta tggtagctct ctttaaaagg
    30841 ctccgatact gccgccacct ccgcctccag agaagccacc gccagaactt ccacttccag
    30901 aagatacgga gtaggtactt gctgtatttg cgacactagc ataatggctc atttgcgcgc
    30961 ttgaatgata aaacatactg tgccagccat aagctacata gagattgata tctggatttt
    31021 caacttgaat ctgatgaacc ttcatcaaat gactaacctt gtccgcatag ccaaataagg
    31081 ttgcatagac caagagacga ttccaaacaa caatactttc caattcagcc ttatccagtc
    31141 gtgcaatctc acgtaacata ttttcaaaac tggtccagag atagtagacc tcagctcccg
    31201 cttcatttag aacaccatca cgattatcta gtcgaagctt ccaataatag aaaacagaca
    31261 aaactaaccc tagaaaacca agtattggca aagggaggta aagatagcca tgaacgtcta
    31321 aactgtacaa gaacaaacca aatccgataa ataggggcaa gatagtcaag acacccatac
    31381 ccacttgcaa agccttttcc aaaccagtta aaggacgata gtaatctggg agcccccaga
    31441 aggaaactcg ttttctcact ccttcttgca tctggttcaa tacctcttca aaagaagatt
    31501 tgagttgaag ccctcttgct tgaatccgtt tttcatcaga aactttggct ctacgataaa
    31561 gactatcaga taccttgtaa tccgcaaaca aattggaaag agtttcttct tttttacctg
    31621 aaaaagctag atttaggcag tctttctcaa agcttgacaa accatcttct tttactagcc
    31681 tcaaaccaac tgcatctcct tctgaaatga tagagacatt cccacggtct atcacatcta
    31741 gcaaggtagc ttgaataagt tgatcaaagg tgaattttcc agctcccttg accaagggac
    31801 tcacttcctc caaggaggtc gagtagactg cttctgataa aaccataggc tctaattcca
    31861 ttgggggttc atagagacga tgatttttag catatttgat tgaaggagcg gtctttcttc
    31921 tatagataaa atagaaacag atgctcaata acaaggagat ggaaaggatc gaagggaaga
    31981 tccaagtaag tagttgttta ctttgatctt tttctttaac gatcgaatcc tctatcttat
    32041 taaactcttc taaacgattc cctttcaagc cctgatccct agcgctagca aaatcagttc
    32101 gcggccagta ggcatgcaat tcaactccac gcttagccgg aagattgtct aaacgaatag
    32161 tataatcaag gttactcttt tcaaccgttc tctctctaaa aagtttccct gtatggaaaa
    32221 agagtttctc agcccccttg tctcccctta catgaaattc aaacttttca atagactctg
    32281 aactatctgt cagaggttgc caatttaatt cagcgatatc atcataaagg aaaagtaaat
    32341 tttttaagtt ccagacgagg tcaacttcaa ctatgtcgcc ctcctgacct ggattataga
    32401 ctctcacagt ataaccatcc gcttcttctg ttacttcgct agtcacatct gctagttctg
    32461 caccgttttt cgcggcctga atctttggat gagggtcaat gtcaaacccg ctaggcatct
    32521 taccagcacg tccaagtccc acgatttggc ccttaaagtc ctcctcaaac tggtaaacta
    32581 tcttctgtct aaactctgcc gtattgtctg catgaatata caaatcccct tgataagagt
    32641 ttatcttgaa atcaatggca aaaacagaga gtggaagaag gcaaaacaag cctaacacca
    32701 gtaagaaaaa agtttttttc atcaactaag cccccttttt atctttctta tcattatagc
    32761 attttttcgt aagtaaaggc ttacttatgt tgaaaaatta cgcatttttc gataaaatag
    32821 gagacagtta ttttttaata gatcagaata ggagaaatca tgagaaaaat atacttatct
    32881 attttcacaa gtctcttgct gatgctagga cttgtcaatg ttgctcaagc cgatgaatat
    32941 ttacgcatcg gtatggaagc agcatatgct ccctttaact ggacccagga tgatgatagc
    33001 aacggagctg tcaaaatcga tgggaccaat cagtatgcca acggatacga tgttcaaatc
    33061 gccaagaaaa tcgctaagga cttaggtaaa gaacctttgg ttgttaaaac caagtgggaa
    33121 ggtctagtcc ctgcccttac ttctggtaag attgacatga ttatcgcagg tatgagtcca
    33181 actgcagaac gcaaacaaga aattgccttt tcgagcagtt actatactag cgaaccagtt
    33241 ttgcttgtca aaaaagattc tgcctacgca agtgctaaat ctttggatga ctttaacggt
    33301 gcaaaaatca cttctcaaca aggggtctac ctttataact tgattgcaca aatcccaggt
    33361 gctaaaaaag aaacagccat gggagacttc gctcaaatgc gacaagctct tgaggctggt
    33421 gtcattgatg cttatgtttc tgaacgtcca gaagcactga ctgctgaagc tgcgaactct
    33481 aagttcaaga tgattcaagt agaacctggt ttcaaaactg gggaagaaga tacagctatc
    33541 gctatcgggc ttcgtaaaaa tgacaatcgt attagccaaa tcaatgccag cattgaaacc
    33601 atttcaaaag atgaccaagt tgccttgatg gatcgtatga tcaaggaaca acctgccgaa
    33661 gctacaacaa ctgaagagac tagcagtagt ttctttagcc aagttgctaa aattctttct
    33721 gaaaactggc aacaactctt gcgtggtgct ggtatcactc ttttaatctc tatcgtcgga
    33781 accatcatag gtctcattat tggacttgcc attggtgtct tccgtactgc tcctctctct
    33841 gaaaacaaag tcatttacgg cctacaaaaa ctagtcggct gggttctcaa tgtctacatt
    33901 gaaattttcc gtggtacgcc aatgattgtt caatcgatgg ttatctacta tggaactgcc
    33961 caagctttcg ggatcaacct tgaccgtaca ctggctgcta tcttcatcgt ttcaatcaat
    34021 accggtgcct acatgactga aatcgtccgt ggtggtatcc tagcagttga caagggacaa
    34081 tttgaagctg cgactgctct tggtatgacc cataaccaga ccatgcgtaa gattgtccta
    34141 cctcaggtag tccgtaacat cctacctgca actggtaatg aatttgtcat caatatcaaa
    34201 gatacatctg tattgaacgt tatctctgtt gtcgaacttt atttctcagg aaataccgtg
    34261 gcaacacaaa cctatcaata cttccagaca tttacaatca tcgccgtgat ttactttgtc
    34321 ctcaccttca ccgtaacacg tatcctacgc tttatcgagc gcagaatgga catggatacc
    34381 tacactacag gtgctaacca aatgcaaacg gaggatttga aataatgaca caagcaatcc
    34441 ttgaaattaa acacctcaaa aaatcctatg gacaaaacga agtgctaaaa gacatttcac
    34501 tcactgtcca caagggagag gtcatctcta tcatcggaag ctctggaagc ggaaaatcga
    34561 ccttcctacg ctccattaac ctacttgaaa caccaactga tggacaaatc ctttatcatg
    34621 gacaaaacgt cctcgaaaaa ggctatgacc tcacgcaata ccgtgaaaag ttggggatgg
    34681 ttttccaatc ctttaacctc tttgaaaatc tcaatgttct tgaaaacaca atcgtcgctc
    34741 agacaactgt cctaaaacgc gaacgcacag aagctgaaaa gattgccaaa gaaaacctgg
    34801 aaaaggtcgg catgggagaa cgctactggc aagccaaacc aaaacaactc tcaggtggtc
    34861 aaaaacaacg tgtggccatc gctcgtgccc tctccatgaa tccggacgct attctctttg
    34921 atgaaccaac atcagctctc gatccagaaa tggttggaga agtcctcaaa atcatgcagg
    34981 acctggctca ggaaggcttg accatgattg tcgtaaccca tgaaatggaa tttgcccgtg
    35041 atgtctctca ccgtgttatc tttatggata agggcgtgat cgctgaagaa ggtaaaccag
    35101 aagacctctt caccaatcct aaagaagacc gaacaaaaga gttccttcaa cgctatctca
    35161 aataaaaaga aaaggctgca tcaaccgtgc agtctttttg ctgtcctcaa aatgaaaagg
    35221 cagattctct atctctacta cttgaaggtc aagaatccgc cgttatccaa agattaatct
    35281 tcaaattttt cataattttt ttcatagaaa tcaattaggc ctagggctgt ttcaaatgaa
    35341 atatttttta cttttgcacg accctgcgcc agagcaatga tagacatttc acgcgcattc
    35401 gtttctttag agatacggta gcctgtgatt ttcttatcac gaacccagcc aacaactgat
    35461 tctacttttt caaagtttga cttagccatg tttttctcct attttcttct ttataatatt
    35521 taattgtata cgtttttact acttttgtca ataaaaaaaa catatattca acgaaaataa
    35581 ttagttcaga attttct
//
LOCUS       DAVMBH010000018        35346 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVMBH010000018 DAVMBH010000000
VERSION     DAVMBH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.018"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(135..1697)
                     /gene="guaA"
                     /locus_tag="VYP30_000996"
     CDS             complement(135..1697)
                     /gene="guaA"
                     /locus_tag="VYP30_000996"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1808015.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            1839..2537
                     /locus_tag="VYP30_000997"
     CDS             1839..2537
                     /locus_tag="VYP30_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1808016.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(2580..3476)
                     /locus_tag="VYP30_000998"
     CDS             complement(2580..3476)
                     /locus_tag="VYP30_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1808017.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3485..4420)
                     /locus_tag="VYP30_000999"
     CDS             complement(3485..4420)
                     /locus_tag="VYP30_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1808018.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4417..5142)
                     /locus_tag="VYP30_001000"
     CDS             complement(4417..5142)
                     /locus_tag="VYP30_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1808019.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(5226..5861)
                     /locus_tag="VYP30_001001"
     CDS             complement(5226..5861)
                     /locus_tag="VYP30_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1808020.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVACDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(5863..6690)
                     /locus_tag="VYP30_001002"
     CDS             complement(5863..6690)
                     /locus_tag="VYP30_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1808021.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(6712..7047)
                     /locus_tag="VYP30_001003"
     CDS             complement(6712..7047)
                     /locus_tag="VYP30_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV1808022.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7048..7764)
                     /locus_tag="VYP30_001004"
                     /pseudo
     CDS             complement(7048..7764)
                     /locus_tag="VYP30_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8277..8888
                     /locus_tag="VYP30_001005"
     CDS             8277..8888
                     /locus_tag="VYP30_001005"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1808023.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            8933..9661
                     /gene="rlmB"
                     /locus_tag="VYP30_001006"
     CDS             8933..9661
                     /gene="rlmB"
                     /locus_tag="VYP30_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1808024.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(9700..10611)
                     /gene="trxB"
                     /locus_tag="VYP30_001007"
     CDS             complement(9700..10611)
                     /gene="trxB"
                     /locus_tag="VYP30_001007"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1808025.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(10677..10901)
                     /locus_tag="VYP30_001008"
     CDS             complement(10677..10901)
                     /locus_tag="VYP30_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1808026.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(10979..11722)
                     /locus_tag="VYP30_001009"
     CDS             complement(10979..11722)
                     /locus_tag="VYP30_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808027.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(11722..12522)
                     /locus_tag="VYP30_001010"
     CDS             complement(11722..12522)
                     /locus_tag="VYP30_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808028.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(12680..13036)
                     /locus_tag="VYP30_001011"
     CDS             complement(12680..13036)
                     /locus_tag="VYP30_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1808029.1"
                     /translation="MLEFIEYLKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNREAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13030..13560)
                     /locus_tag="VYP30_001012"
     CDS             complement(13030..13560)
                     /locus_tag="VYP30_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1808030.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(13560..14054)
                     /locus_tag="VYP30_001013"
     CDS             complement(13560..14054)
                     /locus_tag="VYP30_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808031.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14189..14635
                     /locus_tag="VYP30_001014"
     CDS             14189..14635
                     /locus_tag="VYP30_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1808032.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            14632..15279
                     /locus_tag="VYP30_001015"
     CDS             14632..15279
                     /locus_tag="VYP30_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1808033.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIIYYM"
     gene            complement(15631..16947)
                     /locus_tag="VYP30_001016"
     CDS             complement(15631..16947)
                     /locus_tag="VYP30_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1808034.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVETSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSSIILFLLIIHILIIQSLSPSIQMFLIKFLMRIFPTENYVINTGFWNLLSN
                     PSYLKSIQTSMSMGVTLISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIIT
                     SSISLTILSSNKDIEDIKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILI
                     LVSIIGQFLGRSLVDISGFWQPSLIVISLLVIFYSITKGFYLFQDR"
     gene            complement(16965..17696)
                     /locus_tag="VYP30_001017"
     CDS             complement(16965..17696)
                     /locus_tag="VYP30_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808035.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            complement(18253..18837)
                     /gene="pdxT"
                     /locus_tag="VYP30_001018"
     CDS             complement(18253..18837)
                     /gene="pdxT"
                     /locus_tag="VYP30_001018"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1808036.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            complement(18838..19713)
                     /gene="pdxS"
                     /locus_tag="VYP30_001019"
     CDS             complement(18838..19713)
                     /gene="pdxS"
                     /locus_tag="VYP30_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1808037.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19865..21244)
                     /locus_tag="VYP30_001020"
     CDS             complement(19865..21244)
                     /locus_tag="VYP30_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1808038.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVIAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21539..22462
                     /locus_tag="VYP30_001021"
     CDS             21539..22462
                     /locus_tag="VYP30_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1808039.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHDIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22522..23127
                     /locus_tag="VYP30_001022"
     CDS             22522..23127
                     /locus_tag="VYP30_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1808040.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQSFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEEFDWENL"
     gene            23145..24389
                     /locus_tag="VYP30_001023"
     CDS             23145..24389
                     /locus_tag="VYP30_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1808041.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGDHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24506..24763)
                     /locus_tag="VYP30_001024"
     CDS             complement(24506..24763)
                     /locus_tag="VYP30_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1808042.1"
                     /translation="MDPKKIARINELAKKKKTEGLTLEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24805..26841)
                     /locus_tag="VYP30_001025"
     CDS             complement(24805..26841)
                     /locus_tag="VYP30_001025"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1808043.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(27053..27970)
                     /gene="glyQ"
                     /locus_tag="VYP30_001026"
     CDS             complement(27053..27970)
                     /gene="glyQ"
                     /locus_tag="VYP30_001026"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1808044.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(28164..28925)
                     /locus_tag="VYP30_001027"
     CDS             complement(28164..28925)
                     /locus_tag="VYP30_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1808045.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(29198..30040)
                     /locus_tag="VYP30_001028"
     CDS             complement(29198..30040)
                     /locus_tag="VYP30_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1808046.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(30154..31545)
                     /locus_tag="VYP30_001029"
     CDS             complement(30154..31545)
                     /locus_tag="VYP30_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1808047.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31780..32157)
                     /locus_tag="VYP30_001030"
     CDS             complement(31780..32157)
                     /locus_tag="VYP30_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1808048.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            32372..33349
                     /locus_tag="VYP30_001031"
     CDS             32372..33349
                     /locus_tag="VYP30_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1808049.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33346..34428
                     /locus_tag="VYP30_001032"
     CDS             33346..34428
                     /locus_tag="VYP30_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1808050.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSVTTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     ILRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34492..35346)
                     /locus_tag="VYP30_001033"
                     /pseudo
     CDS             complement(34492..35346)
                     /locus_tag="VYP30_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10633 a         7753 c         6267 g        10693 t
ORIGIN      
        1 ttttgtccaa atgtaaatca cttggaacta ttattcaatt tattcttttt agtaaatgtt
       61 cccgttttaa tcccagttac agtttttaat cctctgtaac cgttgatttt acaaagcttt
      121 taattttttt gcgattactc ccactcaact gttgcaggtg gtttacttgt aatatcgtag
      181 acgatacggt taacatgatc cacttcattt acgatacgta ctgagatttt ttgaagtact
      241 tcccatggaa ttttggcaaa atcagcagtc ataccatcga tagaagtgat agcacggatt
      301 gcaatcgtgt agtcatacgt acgaccgtca cccataacac cgactgaacg aacgcctgtg
      361 ttaacagtga agtattgcca aatatcgcgg tcaagtccag ctttagcgat ttcttcacga
      421 agaatagcgt ctgattcacg aacggtttca agtttctctt cagtgatttc acccatgaca
      481 cggatagcaa gtcctggtcc tgggaatggt tggcgccata cgatatggtc tggcatacca
      541 agctctgtac caagagcacg aacttcatcc ttgtaaagag tattgagtgg ttcaatcaat
      601 tcaaactgca tatcttctgg aagaccaccc acgttgtggt gtgacttgat agtttgagct
      661 gtatccgtac cagactcgat aacatctgta tataaagtac cttgagcaag gaatttcaca
      721 tctttgagct tgcttgcttc gtcatcgaat acatagacaa actcgttacc gatgatttta
      781 cgtttttgtt caggatcaga aacgccagca agtttgtcaa ggaaacgttt agcagcgtct
      841 gctttgacga tattcaaacc aaacttacca ccgagcatgt ccataacttg atcagcttcg
      901 cctttacgaa gaagaccgtg gtctacgaag atacagatca attgatcgcc aatcgctttt
      961 tggagaagaa ccccaacgac agatgagtca acaccacctg atagaccaag aaggacacgt
     1021 ttatcaccga cggtttcacg aatttttttg atctgcatgt caatgaaatt atccattgac
     1081 cagtcacctt tagccttaca aatgttaagg gcaaagttac gaaggatatc atttccgtat
     1141 acagaatgac gaacttctgg gtggaattgg ataccgtaaa tgtgtttatc tgggttttcg
     1201 atggctgcgt atgggcagtc agctgatgta cctgtacgaa caaagtcagc aggaatctca
     1261 gtaaccgcat caccatggct catcaaaaca gtctgttcat caggtgttga ttcaaaaagc
     1321 gctgatggtg tgtgagttag ggttgattga ccgtattcac gatttccagc atcacctgca
     1381 ggaacaactt ttcctccaag tttatgggtc aataactgca taccataaca gattcccaaa
     1441 attggaattc cgagttcgaa gatttctggg tcaatatcaa atgaaccatc ttcatataca
     1501 gaatttggac cacctgatag aataattcct acaggattga cttcacgaac ttcagcagct
     1561 gaaattttat ggctttttag ttctgaaaaa acaccaatct cacggatacg gcgtgaaatc
     1621 agctggttgt actggctacc atagtccaat acgatgattt tttctacatc ttgcaaatca
     1681 gttgaaatgt tgctcatctt tttcctttct caaaagaaat atcttttccc aatattctat
     1741 cacaaataag ggcgaattac caactaaaca aggcgaagtt tgactttttc tagtttattg
     1801 gggtacaata gagaaaagat agaaatgaag tgaaaaatat gctacctgct tatatgaaaa
     1861 tccatgatca gataaaaaag gatattgacg agcaccgttg ggctattggt gagaggcttc
     1921 ccagtgaaag agatttagct gagcagtttg cggtcagtcg catgaccctc cgccaagccg
     1981 tatctctatt agtcgaagaa ggcgtcttag agcgccgtgt aggaagcggc acctttgttt
     2041 ccagtactcg agtacaagaa aagatgcgag ggacaaccag ttttactgaa attgtcaaat
     2101 cccaaggtaa agttccctct agccagctca tttcctacaa aaaaaccatt cccaatgagc
     2161 aagaagttgc caagctagga atttttccaa cggacaatat tatccgaatg gagcgggtcc
     2221 gctatgccga ccaagttccc ctagtttatg aagttgcttc tattcctgaa aaattcatta
     2281 aggactttaa aaaagaagaa atcaccagtc atttcttcca aaccttgcaa aaatatggct
     2341 atcgtatcgg caaatctcaa cagaccatct atgctcgcct tgctaaagaa aagattgccc
     2401 actatttgga agttgaaaaa ggacatgcta ttcttggatt gacccaggtt tcctacctag
     2461 aagatggtac tgcttttgaa tacgtaaaaa gtcaatatgt aggcgaacgc tttgaatttt
     2521 atcttgaaaa taattagatt accacgcaaa aactctctgt cacggacaaa gagtcttttt
     2581 tatttttcta agaataaatc tttcaaagaa atcaaagtta cagcaaacaa tatcattgcc
     2641 ataccaagaa aatcaatggg ataaaattgt tcattcatta ttaagaaggc aaagaaaatc
     2701 gccgatattg gctcaattga agccaacaag cttgacttga ccggtcctat cagactggct
     2761 cctttaagga aagctgtata ggcaaagaca gtcccgataa ggataatgcc tgcaaacgca
     2821 aggagaaaat caagactagt cgggatatcg gcctgtagaa cccctgtaaa aggaagggcg
     2881 accaaacctg ctatgaccat tcccacacca atgaccaagc tgctccccca ctttttaatc
     2941 aaggctatgg gtaaaatgat atacagagca taagtcaagg cagaaaagag accccagaac
     3001 agaccagcag gtgtcatgga taactggtcc aactgcccat gtgttgcgat caggaaggtt
     3061 cctccgatgg cgaatatgat ggaaactatc tctcccagtg tcggtgccac cctatccttg
     3121 atacagctat aaattaaaat tccgacagga caaacatact gaagcaccgt cgctgttccc
     3181 gcattggtct cctgaatagc agacagatag gcgaattggt tgagaaaaag accaatcaga
     3241 gcaaaaataa gaagagacag caaactcttt ctatccttta aaaagaccag tattttatcc
     3301 tttgcagtag cataagccaa gagcatgaga attccaccag cgattaaaag acgcaagttg
     3361 gtcaagacca gagccgaaat tccgtgtgcc attaggtatt ggccactcgt tcctgacaac
     3421 ccccaagcaa taccagccac aactgttagt aaagtccctt ttaaactatt tgacatgtct
     3481 ctccttactc ttctttgcga atcaagttca tcacttgatt gcggtctaat atccattgag
     3541 ctctctcgtc cttttcatag gtacgattcg ataggaaaat agtggcttct tgcttctgac
     3601 gattccacat gataaaggta cctgtatagc ccgtatggtc tagccaatct ccttccaaat
     3661 tccatgctaa agaacgttcc ttgtcatcca aaggagaaaa attttgattt aagtctcttg
     3721 caaaatcatc tgctaaatag tgttctaaaa agatttgtaa atcctttata gtcgaaaata
     3781 aaccagcact cccagcatgt ctacccagga gacgagcctt gggatcatgc actatgcctg
     3841 cctctacacc tctaactgtt ggaacagcaa gctcaactgg cccaaactta gtttccgtca
     3901 ttccccaagg tttccagact tgatccttta aaatcacatc caaatcttga ttaaaaattc
     3961 tttccaaaat aaagcccaac agcaaaaaat ggacatccga ataaagaaag gctggctgac
     4021 ttcgtctgtt gagatgaaac atcgcttcct ttaattcagg ggctgttaaa agatcacgat
     4081 taggaataaa aggatcaagg tctgttgcat gagtcaagag ctggcgaata gtgatgtctg
     4141 gataatcact ctcaggtaaa aaatctatta ccagtctatc aatatctaat tgacctattt
     4201 cccacaagaa ggtacaaact gtgccaaccc caacaacctt actgacacta gctaggtcat
     4261 aaactagtcc tgcctcagtc tgcaagccat gctctgggtc actctggcct aaatagaact
     4321 ctgtccattg attgtcctta aaatacgcaa aagaggctcc gggataaatt cctgcctcga
     4381 tttgttcttc tattttttta ataatcttgg tccacttcat acttcttcaa accacaattc
     4441 aacattattt ctatctttac caaggaagaa tttttcagac ttaggaataa aatattcagt
     4501 agactcaaac ttctggcgaa gacttgctat gtctaattca ttgaccaaga acttgagcat
     4561 agataagtcc caggtaaccg tattgtccac agtcaaatcc tgcccctgag ctggaataaa
     4621 atcaagggat gccccaattt cagatgattc caagaaactt tcgatatcag ttgggagatg
     4681 taattccata gaaatctcaa atttacttaa agaaattgat gccaaatctg tttgaaattc
     4741 aggcttttct cctacttcta ctagacttgc tctgtcatct tccgcatgaa tcaaaatcaa
     4801 atcatcttct ggtgagaaaa tttcaaaagc gtagccattt tgacctttat ataatcgatg
     4861 aatcgaatct gttttagata agattccttc aatttctaag ggattttcca ccttgacaat
     4921 caatctagct agtttttttc ttccctctac cttacgagta cgcatactgg gagcttcttc
     4981 taaaaccagc ttttcaagac ccgtttggtc acctagtgac agaaaggccg attcttctaa
     5041 caaggccttc attccaaggg tttcaatata aaatgtttca tttaattttc tattattagc
     5101 ttttaaagta ggaataatcc gtacaatctg atttacattc ataaattcct ccgtcacttt
     5161 ttattttaaa ggattttaga attttttaca agatattatg ctcaaattta acattattta
     5221 gctatttagt aaagatagtc tttcaaggct tttgacaaag cctgataacc agcaatactg
     5281 aggtgcagtc catcagttgt atattctttt ttgagttggc ctgcttggtc tgtcaaacaa
     5341 tcaaatactg gcacaaattc cacctgcata taggcagatg caagctcttg ataggcttga
     5401 ttccagttct gaattttttc attcgagcgg atatagactg cctgctggta ctcctctccc
     5461 tcattgacag gcaaaatgga aagcaattta atctctgtca atggataatc gcaagcaacg
     5521 gattgaatga tagcttcgag attattgaga gcctcattca caggaacatc ctttccgata
     5581 tcatttgtcc caatcagaag aaaaatttta tctactgctc caccatatag atgagcatca
     5641 aggttctcta gtaacagtcc tgtctgatag ccacgaattc ctcgattgac aatcgtcttt
     5701 gaagtcccaa atagctcctg tagaggataa tactcgacaa tggaatcccc aataaaaaga
     5761 atgtttggtt ctacaacaga aatgtgattt aggtgacgat acttggtttg aattttttct
     5821 tgttccttta ggagccaatt ttctaataac tgtactgcca cttcattctc ctttttctaa
     5881 ccagttttcc aagacttgat aaactcctcc ttggctgttg gctggtgcta gagcagtcgc
     5941 cacagctttg gctttctcat cagcattttc catcgcatag gcaattccag ccatttcaag
     6001 catttcaaca tcattttcac tatcaccaaa agccatgatt tcttgggatt tcaagtccca
     6061 gcgcttgagt aattcctcca agccccatgc tttatgaatc ccagcttgga ggatatcaat
     6121 gcaaccatag ccactggata cagctcggac acggccatca aagagagcat tgatttcttc
     6181 caaaaccgaa ctcaaacgtt cctcaccaac aaccatgctc atcttgagca caccaccaaa
     6241 gaggtcagat gttaattcat ccacaaattg catccgttgg tagaattttt caatcatttc
     6301 tggagtcata aaactttcaa gatctgtaaa aatcgtacct tccttgacaa aatcaccctt
     6361 catccccgtt acaacaaact ggtcctgaca cgctcgaccc ttgaaatgag ccaaagcctt
     6421 gttgacaatg gcgtcatccc atgtctgagc ctgaatcaat tcattgtttt caaaaatacg
     6481 agcgccatta gcaacaacca gaaccactcg atccaccaag ggactcagta gttgtctcat
     6541 gcggtgaatt tcattgcccg tcgcaatgac aaaacgaatg cccctttgat ccaactgatc
     6601 taaaatcttt tccaatcgtg ggagatcaag ctgacctcta gcatccagca aggtcccatc
     6661 catatctgtc gcaattacct taatcatcat ttactttcct ctggattcaa gctaatacca
     6721 cttcaatccc acatgttcat tcatttcttt ataggctgta tcaattcgtt ccttagtcgc
     6781 ttcatctaac tggtcacgat gactgccacc ctctataaaa tcttccaaaa tataagtttg
     6841 gtaatgatac aagggatatc cttctggtga aaaggttccc tttggtgttc gattgaccca
     6901 agtaggatga gctttagctg ttccgatagt tgtttttcca tccttcttct tgatggtgac
     6961 atccatgaga acaccacgtt cagtccactt agcattctct tcatctccca tagattcaat
     7021 ccgttgattg gaaatgaagt tccccattta atagataatg agtttcttat ctccatcttt
     7081 ttcaaccgtt tcagatggtt caacaacgtg aggatgccct ccaaagataa tatccgctcc
     7141 ccaatcgatc atcttgtgat aaagagcttt ttgttcttca gttggttcca atcgatactc
     7201 aacacccatc tgaagcatga taatggtgat atctgcttcc ttctctgccc gttcaatttc
     7261 agccttcatc ttatcttcgt ttaaatctga aagataacga ttatagtctt cctgagaaat
     7321 atactgctca attccattga aaccatagga ataggctaac aatgcaacct tgatagcatt
     7381 cacttcctta atgaccagcg gagcctgaac acgtggttcg tgcgtataaa ctccgattgg
     7441 agtgattcca gctttctcaa taatatcggc cgttgaaata actccctcaa tttgcgaatc
     7501 caaaatatga ttatgagcta aatccagcac atgataacct gcctccttaa tagcatccat
     7561 aacttcagca ggagcattaa agagaagata acccgctaaa taatgatcct tattaatggt
     7621 tccttcaaaa tcaccaatag ctaaatctgc ttgcttgagc caaggagtca catactaaaa
     7681 attttcatga aagtcatagg taccgtcttc ttttttagct gaaaagaaaa gtccatcgtg
     7741 gtagagcaaa tccccgtggg ccataattct ggcagttttt tcctcttcct actcctgaga
     7801 cctttgctta gtcccctctt gagaaatagt atctcgtttt tgactagtca agggattcct
     7861 tggaagcttt caaacaacaa gaccaagccc attgataaac caactgctag caagagtatc
     7921 gccacaaatc ccttattgct ccacttgcga taactcctaa aaagtttacc aagcccttca
     7981 taaaacgaaa agctaaacca ccctgatttc gattttgtct tctttgtatc ttcattctcc
     8041 ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt tctttcacaa
     8101 ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc tttcaattct
     8161 tgtcattttg tgatatcatg tagaggaaat gaactaatcc acagtggctt attccaagta
     8221 taccacttgg gctttggcag tagctaactg cactaaacat aatataagga gagaaaatgt
     8281 ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat attatccgtg
     8341 aagggaatcc tactctacgc gcgattgctg aggaagtcac tttcccccta tctgaccagg
     8401 aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagat cctgtcatgg
     8461 ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta gatatctcaa
     8521 aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact ccacaggaag
     8581 cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct gttcaagatg
     8641 ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg
     8701 ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa caccgtatca
     8761 aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt aacggtatca
     8821 tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt ttactgattc
     8881 ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag gcatgaaaac
     8941 aaatgatatt gtctatggtg tccacgccgt taccgaagcc ctccttgcaa atacaggaaa
     9001 caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca aggaactagc
     9061 tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa aatctctctg agatgactga
     9121 aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata gcgagctaga
     9181 ttacatcctt gcaaaaacac gccaagaaga aaattcactt ctattgattc tagatggtct
     9241 aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca atgtttcagg
     9301 tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca aaacagccac
     9361 aggtgctatt gaacacgttc caattgcccg agtaaccaac ctcagtcaaa ccttagataa
     9421 actcaaggat gaaggtttct ggacctttgg aacggatatg aacggtactc cttgccacaa
     9481 gtggaataca aaagggaaaa tcgccctcat cattggaaat gaaggaaaag gtatctctag
     9541 caacataaaa aaacaggtcg atgaaatgat taccattccg atgaatggac atgttcaaag
     9601 ccttaatgcc agtgttgctg cggccattct catgtacgaa gttttccgaa atagactata
     9661 aaaaagtttc cagtcatctg attggaaact tttttatgat taactatgtt ctgtaatgaa
     9721 tttataggct tcttgaccag cgatagctcc atctccaact gctgttgtta cttggcgaag
     9781 gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagtct tcatgtggct
     9841 atctgtcaca atccagcctg cctgatcttg gatattcaat tctttaacaa aatcgctaag
     9901 agggtccaaa ccaacataga taaagacacc accgaaggct tgctctgtca cttgacctgt
     9961 tttcacattt tcaaaaacga cagattctac tctgttttca cccttgattt tccttactac
    10021 agaatcccat ataaagctga ttttctcatt ggcaaaggcg cgatcttgta aaaccttttg
    10081 ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa
    10141 gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt ggtcacggaa
    10201 gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt cttcttctcc
    10261 aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac gtgtttcata
    10321 tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat tttcaacata
    10381 accataaatg tgctcaacac caagattttc aagtggttca aacatctttt cagccaattc
    10441 aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat tattcatctg
    10501 accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag cagcatacaa
    10561 ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca tatagattcc
    10621 ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg caaggattat
    10681 gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac aaccaagact
    10741 ccaatcataa tcatatcata gagatgggct tggcgagcct tggctgtctt atcaactccc
    10801 gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat ggtggtcaat
    10861 atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct catttctatc
    10921 ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat ctattatatc
    10981 aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct ttaggggtgt
    11041 ggataatctc atccggtgtt ccagactcga tgattttccc cttatctaag aagagaatct
    11101 tatcagccac ttgggctaca aaggacatgt catgactaac caaaatcatg gtttgacctg
    11161 acttagcagc atctgcaata gacttttcta cttcaccaac caattctggg tcaagggctg
    11221 aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc gctagggcaa
    11281 cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg tccgaaagcc
    11341 caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat aatttcttga
    11401 caacaaccaa gccttctttc acattatcaa gtgctgttcg gcgttcaaac aaattaaact
    11461 gttggaaaac catagacaac ttacgacgta gggcaaggat ttcttcttga gtgattttag
    11521 aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt tcaagataat
    11581 tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag gctacaactt
    11641 cccctttttg aatatccaag tccagatgat ccaagacagt ctgtcctgaa aaggatttgc
    11701 ttaaatttga aatcttaatc attaacgaag gtctcctttc acatctgttt gcactgtatc
    11761 aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa ttccgatatt
    11821 gaccacccaa taaacaaggg caacggagat gaagcgttca aaatagcgat aatcagctcc
    11881 acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag ctagagatgt
    11941 tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca ccgctgcatt
    12001 aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc gtgccgcctc
    12061 aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag cataagctgc
    12121 ctcattaaag gcaaaggcga caatcgcaaa agctgcagct ggaatcgcat tgatattgag
    12181 accagttccc cattgctgat tgagggcttt caaagccaaa gggattccgt agtaggtcaa
    12241 catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg cctgcaaggg
    12301 atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc
    12361 aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga caattctagg
    12421 gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca attgcatcaa
    12481 gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat cctcttctga
    12541 taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg gtcagataca
    12601 gactttgtct acctactagg ttatcatact ttgaaacagg gaagttatat attttatcta
    12661 tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt cgataaccga
    12721 tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata ccgtcacttg
    12781 ctagcaactc agccgcttct cggtttgaca aacttcctac cttatctttt agccctaatt
    12841 cacggtattt gatcccactg gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta
    12901 gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg gctttatagt
    12961 ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat ttgaggtatt
    13021 cgataaattc taacatgtgc ttctccttct attgtttcta tctttaaaat ctactccttc
    13081 atgctccaag agccaagctt tcttttccac tcctgcagca tagcctgtca gacgcttgcc
    13141 tgctcccaac acacgatgac aaggtactag gatagaccaa ggattgcgtc ccactgctcc
    13201 accaattgct tgagcagaag ccacttgcag gtcttgagca atttgtccat aggtcactgt
    13261 ctgaccataa ggaattccct gtaaatagga ccaaactctc ttttcaaaat tcgttccaat
    13321 tggcgccaag agcaagttgg ataaatcctg aggctcgcct ttaaagtaat catctaagca
    13381 agcaataact ggatctaaaa taggatgact aacaacttct tctatcgttt catctcctag
    13441 tcccctctca aaatgcttct gctcctgaac ccaaattcca tacaaataat ggtcatcagc
    13501 tacaagtgat agaataccaa ttggtgagga gtagagtatt tttacatact tcttttgcat
    13561 tatttcttta atttttgata ggccaagcgt tcgccatcta ctggcacctt accaacttgt
    13621 ttaaaaccaa gtttttcaaa aatatgttgc ataaccttgt tttcagcatg cgtatctgag
    13681 cgaaaatcaa gataatcaaa accttcaatc aagccctcta agaaggtttg agcaactcct
    13741 tttccctgca catctgctgc cacagcaata cggtgaaaga ctagatactc tgactctcca
    13801 gcttgccagt ttccctcata aatagcttca taggcctcct ctggactctt ggtcacagca
    13861 gcataggcta gcagttctcc ctcttccaag gctacgtagg cttgccctga gataatatca
    13921 tcgataataa catctgcatt tggatagcca ttttgccact ggtcactacc agcatctgct
    13981 aaacattttt tggcatcctc catcacctgc atgatggcat ctacttcatt tggaaaagct
    14041 aaacgaattt ccatcttttt tcctcatttc tgactagttt ctcccatcat agcataattt
    14101 aagtatttct acaagcagtt aaaacttgac tttgtgtttt tgttatttta taatctagtt
    14161 atcaaaacta tataaaaagg agttgaaaat gaaaactacc ttttcctacc caaaatgggc
    14221 agaaattcca aacattgacc tctatctgga ccaggttttg ctctatgtca atcaggtctg
    14281 cgcccctatc tctcctaata aagacaaggg cctaacagca tctatggtca acaattatgt
    14341 gaaaaatggt tacctgacaa agcctgacaa aaaaaaatac caacgccaac agattgcccg
    14401 tttgattgct atcacaaccc tcaagtctgt attttctatt caagaaatag cccagacact
    14461 taatactcta caaactcaag caagttcaga ccaactctac gatgcttttg tggactacat
    14521 gaaccaagga attgacccag ctaaccctat tatccaaacc agctgccaaa ccgttaaact
    14581 ctatcatcaa actctagact taatcgatca tactcaagag gaggtaatcc aatgaacact
    14641 agtcttaaac tcagcaaaca actcagtttt ggagaggaga ttgctaatag cgtgacccat
    14701 gctgtgggtg cagtcatcat gcttatcttg ctgcctattt catccatcta tagttatgaa
    14761 gcacacggat ttttatcctc tatcggcgtt tccattttcg tcatcagtct ctttctcatg
    14821 ttcctatcat ccaccattta tcactctatg gcctatggtt cgacccacaa atatgttttg
    14881 cgaatcattg accattctat gatttacgtt gccattgccg gctcatacac gcccgttgtc
    14941 ttgaccttga tgaataactg gtttggctat ctgattattg tcatccaatg gggaacgacc
    15001 atctttggta ttctctataa aatctttgct aaaaaggtca atgagaaatt tagccttgct
    15061 ctttacctga ttatgggctg gttggttctg gctatcattc ctgccattat caatcaaacg
    15121 acacccgttt tctggagtct catggtaact ggcggactct gttatacagt tggagctgga
    15181 ttttatgcca agaaaaaacc ttatttccac atgatttggc atctctttat cctagctgcg
    15241 tccgtactcc aatatattgc tattatttat tacatgtaaa actctcagta ggcagagcct
    15301 gcttagagtt ttacaaacga atttcccaaa gaggaagcaa tatgaaagca gtcattgctt
    15361 gtgttcataa aattctcaga atcatttaca aactactctc caccaagtag acttatcaaa
    15421 aagaaaaggc gctaggactg aagaaacagt tctaacgccc aaattaaaaa aatttcaact
    15481 acagtatagc acaggaaatg attttttgcg cttttttact gttttttcaa ataaaaaaag
    15541 acaaagtttt atccttgtct tttagtttta gtattgcttt ggtttcaatg tcaataagtg
    15601 tgttcttttt ggttcagtaa ctattccaat ttatctatct tgaaataaat aaaatccctt
    15661 tgtaatacta taaaaaataa ctaacaaaga aataactata agactcggtt gccagaaacc
    15721 tgatatatct actaaactac gacctaaaaa ttggccaata atgctaacta aaattaaaat
    15781 aattaaattg aaaattactg acactaataa aattaacacc gaatgtatta ttgcctcgcc
    15841 tatacgtatt ttaaaaagtt gtaatcttga cactcccagt gtctttaact gtttaatgtc
    15901 ctcaatatct ttattagaag ataaaattgt aagagaaata gaactagtaa taatcagaat
    15961 aattggtgca gacatataag caataaagga agctcttgct tcgtttactc cgtttgctgt
    16021 attcatgaat gaatacatat tttgggtgta aagaataaac ccagaaatga gagttactcc
    16081 catgctcatt gaagtttgta tacttttcaa atagctagga ttggatagta gattccaaaa
    16141 gcctgtatta attacataat tttcagttgg aaatatcctc attaaaaatt ttattagaaa
    16201 catttgaatt gatggagata gtgattgaat aataaggatg tgaataatta ataaaaataa
    16261 tattatgctt gactgttttt caattatttc tttgtttctg ataaaacctg ctgaaacaat
    16321 agaacctata catagtagcc ataggaataa acgaacagag atgttaacaa atccagttac
    16381 tgtaactttt ctttttttct tttttggttt taatattgat gatattttaa gtattcgact
    16441 tgaataaaag taagccccta tcccgacaat tgttgggact ataaaaatac tcaataaaat
    16501 tgattgaatg ttggctgtaa taactaaatc aggtaactca tctcttccta ataaattttg
    16561 taaaaatttg taataactat ctgccatgat aaatgaaagt attgtaccaa tactactaac
    16621 aatcactgcc attaaataaa actgtccaga tactaataaa gatagctgag ttctgcttgc
    16681 gcctaagata gtccataatt ggtaatcctt tttaaagata tctattagca gtcttatatt
    16741 atttgaaata aggaaaaata gagtagtccc gccaaaaatt attagcattt gaaaaagttg
    16801 tgaagcgtta atattagcag tcttgattga actagcaata ccaaataaag atgtttcaac
    16861 aatcaggcta gatacaaata gtaatggtat tgttcctaac cattgtcttt ttgagtactg
    16921 aaattggtaa atgattaatt ttagcataat aaatcctcct caaattaatc tttactactt
    16981 tcaagtgctt ggtagagctc atcagctgaa ggtttaataa tttgtcgaga tatttttccg
    17041 tcttttaaaa tgagtgctct gtcagttttt gaagccaact caatatcatg agtgaccata
    17101 agaacacatt ttccttgact cgctaaatta cgaagtgttt caaatataag ttttcttgag
    17161 acgctgtcca gagctcctgt tggctcatca gcaaaaataa ttttactatc agctattatt
    17221 gcacgagtaa tagccacttt ttgctgttct ccacctgata aggtagcaac taatgatgat
    17281 agttctgctt taaaattcaa actatccaac atttttttta ctttattgct atcaacactc
    17341 tttcctgata gtctcagagg aagtgtaaca ttttctagta caggtagagc aggtaccaga
    17401 ttatagtttt gaaaaattat tgcaatatct tgtcttctaa atttagcaag cttcccttct
    17461 tttaaggtat atggatttac accattgata acaacttcgc cacttgttgg ttcagataaa
    17521 cttgataagc aacttagcaa agtagacttt ccagaaccac tgacaccaag tattgataca
    17581 aattccccat aattgacaga taaggaaata tctttcaaaa tagagacagt tttgtcttgc
    17641 cctaacaaaa attcttttga aaggtttgag actttaacag ctacattatt aaccataata
    17701 aatcctcctg attccagtgt catctttgat ttaattatac aatattggaa ttctattaat
    17761 atcaagtaag taacttatga aacgtatttt taatggataa aatttctatt tcctctggat
    17821 ctcgaataaa ggtctttagc gaactaagaa ttttttctat taccataata gtatcataaa
    17881 tgagacttga ttgaaagcgt aaacatagct ttgttaagtg atacaactat tctatacaaa
    17941 atttaaacat aaaacttagg tatacttaat aaatgagaat ttaagttagc tataacaaag
    18001 atagtagcat atgtaaaact ctaagcaggc agagcctgct tagagtttta caatcgaatt
    18061 tcccaaagag gaagcaagat gaaagccgtc attgcttgtg ctcataagat tctcagaatc
    18121 gtttacaaac tactctccac caagcagact tatcaaaaag aaaaggcgct aggactgagg
    18181 aaacagttct aacgcaaaaa ctaaaaaaat ttcaattaca gtatagcaca ggaagtgatt
    18241 ttttgagctt ttttactgtc ttttttcttt acacatttcg ataaagtact ggtgtaagtg
    18301 agcatcatct gtcaattctg gatgaaaaga agttaccaac atattttttt cttgggctgc
    18361 aacgatttga ttatcaactg ttgctagaat ttctacatct tctccaacac tgctgataat
    18421 tggaccacgg ataaaggtca ttggaatctt gccaactccc ttacattctg cttccgtgta
    18481 gaaacttcct aattggcgcc cataagcatt acgctcgacc accatatcca tagttcctag
    18541 atgactctct ttctgagaag tgatttcctt agccagcaaa attaagcccg cacaggtccc
    18601 aaacactggt aagccagata gaatggcttc tcggatggga agtagcatgt tctggtcacg
    18661 taagagcttg cccatggttg tagactcacc accaggcaaa atcaaacccg acaagtcact
    18721 ctgatcttgc tgaaaatcat ctagatttct gagttctaca ctctcgacac ctaattgatc
    18781 tagcactttt gcatgttctg caaaggcccc ttgcaaggcc aatattccga ttttcatcta
    18841 ttttcctcgt tcagccatga gaatttggat ttcattttca ttaataccaa ccatggcttc
    18901 tcctaaatct tcagagattt gagctaggat ttgaggatta cggaagttag tcacagcctt
    18961 aacaatggca ctcgctcgtt taacaggatc tcctgacttg aaaatacctg aaccgacaaa
    19021 gaccccctct gcccctagtt gcatcattaa cgcagcatct gctggcgttg caacacctcc
    19081 agcagcgaaa tttacaactg gcaattttcc atgttcatga acatattgga ccaattctac
    19141 agggacttgc aaatccttgg cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg
    19201 gcgaatttcc tgattcatca tacgcatatg acgaacagct tggacgatat cccctgtccc
    19261 tggttctcct ttggtacgaa tcatggaagc accttcagcg atacgacgca aggcttcacc
    19321 caaatcctta gcaccacaga caaaaggaac ttggaattct ttcttgtcca catggaaacg
    19381 gtcatcagct ggagatagaa cttcactctc gtcgatataa tcaatttcaa tagcctctaa
    19441 aatctgagct tcaacaaaat gcccgattct gaccttagcc attactggaa tactaaccgc
    19501 ttcttggatt tccttaatca tctttgggtc gctcatgcgg gaaactcctc cagctgcacg
    19561 aatatcagcc ggaattcgtt ccaaggccat cacagctgcc gcaccagcag cttctgcgat
    19621 acgagcctgt tcaggattct gcacatccat aataacacca cccttgagca tctgtgccaa
    19681 gtttttattt agttcataac gattttcagt catttgtttt atcctcatca tttgtattgg
    19741 tagctacctt ttcattttaa gtcagaacag aatgaagcac aagataaaaa aactataatt
    19801 gtatggggac agattagcta aaaactatct gaccttaact taaggccaga tagctcattc
    19861 atttttattt ttcagccgta agggcagcca ttgtgatgta gttgtatggt ttgttgaagt
    19921 gtggcaagaa gaagaggtct gtcaatgcca atttatcaat tgtcacatgc tcttggatag
    19981 caagtgagaa catgtggatt cccatgctaa ttgcaatatc atgggaaacc atttgggcac
    20041 caagaatttc acggctatct ttgtcaaaga caatcttaat tgctacttca tggttgtcat
    20101 gtttcatgaa ttctggtttt tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag
    20161 cagctttcgc tttttcaaga gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga
    20221 taccatttga accttgaaca ccgattcctt ccaattcatg tccacaagcg ttgtaggcac
    20281 caacgatacc agtgcgaaca gcatttgaag caagagcgat atagcttgta tctttacgag
    20341 cattgtcata aacagtcgca cagtcaccaa cagcgtaaac gcctgggata gatgtttctt
    20401 gtttcttgtc tacaaggaag gcaccgttgc ggaagagttc gatcttacca tcagcaaggg
    20461 ctgtgtttgg acggaaacca actgcaagga taaccatatc cacgtcaaag ctttctttgt
    20521 cagtaatcaa gcgttcaact ttaccgtcac cttcgattgc tttaacagtt tgacctagag
    20581 ccaagcggat gttgtgatct tccaagttct tcgccatcat ttgtgtgaag tctttgtcat
    20641 agtaaccgtt caagacagta tcaacgatat caacaaggac aacttctttt ccaagacgtt
    20701 caaaggcctc agcaagttca acaccgatgt aaccaccacc aacaacggcg atacggtcga
    20761 ggtgttggct cttgtcagaa agtttattga taacttcttc agcattttgg tacaatttca
    20821 cgaattgaac attttcaaga gttgctttaa attcgcggtt tcctttaaca atttcaacac
    20881 cttcgattgg tggcaagatt ggtgtagaac ctgtagcgaa aatcaatttc tcgtatgatt
    20941 ctttgtgttc ttttccttca acttccgcta taactacttt gttatcatag tcgattgaaa
    21001 gaacaggtga gttcatgtaa actttagcac ctttagcttc caatttttct ttatcagaat
    21061 agaacaagcc ttcagcaccg tcaatttgtt caccaatcca aagagccatt ccacatccta
    21121 gaaaagagat gttagagttt tggtcaaata caacaatttc gttctcattt ccaaaattat
    21181 ccaacatggt attgatacat gctgtaccag cgtggttagc accgactaca acgattttac
    21241 tcataaaaaa tttcctgcct tcattctaaa tttactttac tagtatacca tttaccgtta
    21301 gcgtttacaa ggggggtact attatttcag cattttttat caaaaataat tccccattta
    21361 tcctgttttc aagcctcatg aattttatga gcatatttct tgactttttc caaattttgt
    21421 ttgtgaaaat tctaacttta tggtattata ataacatgaa aataaaatgt aagggcttca
    21481 atttagataa ttatttgata ttacaactta ttttctataa gagaaaggag ttggtagctt
    21541 gactcttcgt tcacattctg aacggctaat ggggactact atcactattt cattagtgga
    21601 tgagcaagcc gatatctttc tccaaaagtc ctttgacttg ctcaaagaac ttgaataccg
    21661 cttcaacgcc aatagtcaag aatctgagtt gatggaaatc aattatcaag caggaatagc
    21721 ccccgtcacg gttcatccag acctgtttga gctgatttca cttgggttag agcatagcct
    21781 agcgctctct agccacctca atatcagcat tggtccctta attcaaacct ggcgtatcgg
    21841 tttttcagat gccaaggtcg cccagcctca agagattgaa tcggtgctgc ctctaatcaa
    21901 tcctcatgat atcgagttag attcttctac ttctactgtg tttttaaaac agaaaggaat
    21961 gaagatcgat ctaggttgtt tagccaaagg atacagtgcg gataaggttg cccaatttct
    22021 taggaaagag ggggtgactt ctgccttgat caatctggga gggaatatcc tgaccattgg
    22081 aaaaaatcag gcaagagggg ataacccatg gcaaatcggg attcaagacc cagccaatcc
    22141 taggggaaat catttaatga ccatccctgt tgtcaataaa tctgtcgtga cttcaggcat
    22201 ttatgaacgt cacctgaccg tcgatggaca agattaccat cacatttttg acagtcaaac
    22261 aggatatcct gttgaaacgg aactagcgag tctaacaatc atctctgata aatcagtcga
    22321 tggcgaaatc tggacgactc gactctttgg agaaagacct gcttctatcc tctggcaagt
    22381 cgaaagtttg gagggcatcg aagttatcct catcgataaa gaaggccacc taagctgttc
    22441 ttcaggaatt cctactctat agagacaact gtttcaatgg aattttaaaa ttgtattatg
    22501 taaaaagaga aaggaaatct catgttaaaa cttattgcta ttgttggaac aaattcaaaa
    22561 cgttctacaa accgtcaatt gcttcaatac atgcaaaaac actttgctga caaagctgaa
    22621 attgagcttg ttgaaatcaa ggccattcct gtcttcaaca aaccagctga caagcaagta
    22681 cctgctgaaa tattggaaat tgctgctaaa atcgaagagg cagatggcgt tattatcggt
    22741 actcctgagt atgatcactc tattccagct gttttgatga gtgctcttgc ttggctatct
    22801 tacggtatct acccactttt gaacaaacca atcatgatta caggtgcttc ttacggtacg
    22861 cttggttcat ctcgtgccca attgcaactt cgtcaaatct tgaatgctcc tgaaatcaag
    22921 gcaaatgttc ttccagatga attcttgctc tcacactctc ttcaatcatt taacccaagt
    22981 ggcgacttgg ttgaccttga tgttatcaag aaattggatg ccatctttga tgacttccgt
    23041 atcttcgtga agattactga gaaattgcgc aatgcgcaag aattgcttcg caaagatgca
    23101 gaagaatttg actgggaaaa tttgtaagat aggagaccga aagaatgaaa tttgttggac
    23161 ttgttggatc aaactacgat caatcatata accgcaaact cttggaattt atccgtcgca
    23221 atttcaaatt caaatttgaa ttagaagtac ttgaaatcga cgaagttcca atgtttaacc
    23281 aagacgaaaa atgggacgaa agcttccaat tgcgtttctt gtataacaag attacacgtg
    23341 ctgatggtgt cattatcgcc actcctgagc acaaccacac tatctcagct tcactcaaat
    23401 ctgtacttga atggctttca tacgaagttc atccatttga aaacaagcct gttatgattg
    23461 tgggtgcatc atactatgac caaggaacat cacgtgctca agttcacctt cgtaaaatcc
    23521 ttgatgctcc aggtgttaat gcctacacgc ttccaggtaa cgaattcctt cttggtaaag
    23581 ctaaggaagc ttttgataac aacggaaata tcaccaacga aggcactgtt aaattccttg
    23641 aaacttgctt agataacttt gttaaatacg taggagtcgt ttcgaaattg aaaaaaccaa
    23701 aaccaatcga atcagaagac ttggattgtg gaaaaccaat cgctacaacc atcacagaag
    23761 ttgaccctga cgatccagaa tgggtagaaa aagttgcagc aatcactggt gctgtttctg
    23821 gtgataccta tgtcaaattg gaccacggta tcctaacagt taaccaaatt gatatgttct
    23881 tgaaagctat gccatttgaa ttgacatacg ctgacgacaa caaccaattc ctctactaca
    23941 acaacgctca ccaagatcca gacactatgt tcgctaaacg tgtaccacct caatcaggta
    24001 gccgtatgtc gactgttcat ggttctcttc caccagcacg tatgaagaac gtagagtggg
    24061 ttatcggaac acttcgcaac ggaaaccaag aatacgtccg tacgatcgtt ccaggttctc
    24121 ctgcaggtgt tatcaacact cacaactacc aagcaatgta ctatcctgat ggatcatacg
    24181 ctggtatcaa tgaaattgtc tttaacttcc aaccatggct tgactggtac ctaaaagaga
    24241 ctggtcaacg tttggtgggt ggtagcggac catttgctcc tgctgccgga gatcatggag
    24301 acgccgatgc tacttctggc gcttctgatt caggggatgc tggaggccac ggtggtgacg
    24361 cagacgctac agccggtgca agttactaat gatagttttt aggaaccatt atggttcctt
    24421 ttttagcgaa aaaagactag caaacacaaa ctgctagtct ctttgttatc gtttcatcta
    24481 tctttgttaa aaaaaagagt acatattatg aatttgggtc atcaagacta cggccatgta
    24541 atcctttttc acgttgtact tggcgtagtt tttctggtgt aacatcgttt ccttcttcgt
    24601 ccacaatttt gattccttca atgtgatgac gaacagcgcg acgataacct tcgatgtact
    24661 cctcacgtag tttggcttgt tccacttttt cttctagtgt taagccttct gtttttttct
    24721 ttttagcaag ctcattgata cgagcaattt ttttcggatc catttcttct cctctgtaat
    24781 aagataaagt ccgtttatca aattttattt agtgttaatt tggttaaaac aagcaaactt
    24841 agctgctttc ttggttagtt gtgacaagat tgccaaacga ttttgacgga cagcctgatc
    24901 ttcagccatt accatagtat tttcaaagaa agcatcaatg actgggctaa gcgcaaagag
    24961 ttgtttcaat tgctgacttg caggtcctga taaaacgagt gtttctactg cttctgccaa
    25021 agctttttct tggtcattct caaatagttc tgaatcaact gtagcaaccc cttctgcctt
    25081 ctcagccagg ttaaaggcac gagaaagtga ttcaacagat ggtttaaaat cttcttcctt
    25141 gcttacttct acgagagcac ttgctgcttc caacatatct gccacaacaa agtttgaacc
    25201 tgcaagaact gcttccttga tatcttttgg agtagagccc atcatcttat caacacgagc
    25261 cttgataaag tccataacct ctgctttatt ttcataagtc aaactgtcaa atttcaatgc
    25321 ataaaggcta tcaatcagct catccatagc aatgtgccaa ccaaaggcat ccaagatacg
    25381 aaccacacct tgagttgcac gacgaagggc ataagggtca ttagaacctg atggaatcaa
    25441 tcctactgag aagaaactca aaatcgtatc caatttgtct gcaatggcta gaactgcgcc
    25501 gaccttgctc tctggaagtt ctccttcagc tgatgtaggc atgtagtgtt cacgaatagc
    25561 agctgccacc gctggagttt caccagcaag aagggtgtat ttttcaccca taattccttg
    25621 gagttcgtca aattcaccaa ccatacctgt caacaagtca aacttgtaaa tggctgctgc
    25681 acgagcaagg tcaactgttt catccactga caaaccagct ttttctgcca aaagtacagt
    25741 gatttgaccc gtacgaatca tgtgttcacg aagggaacca atcttctcat ggaaggtgac
    25801 attgtttaat ttttcaacaa gatctgaaat caccaatttt tggtcttcac gccagaagaa
    25861 ttctccgtct tccaagcggg ctaccaagac tttttcattt cctttgatga catttttcaa
    25921 acgctctgcg tttccgttac gaacagaaat gaagtttggc aagagttttc catcttgatc
    25981 acgaacaaca aagtaacgct ggtgttcctt catagaagtc accaagactt cttctggaac
    26041 ttcaaggtat ttagcatcaa aacttcccat gaaggcagtt gggtattcaa ccaaattcaa
    26101 gacttcattc agcaaatccg catcaatttc gatacgtaca ccatgttttg cctcaatttc
    26161 cttgatttgg tcaacaatca tttgctcacg ttcacatgga tctgcgatta caaactgctt
    26221 acgaaggtct tcttcatagc tcaatgctga ctgaattttg gtttctttcc ccaagaaacg
    26281 atggccacgg ctcacacgac ttcccttgat atcaaggaaa tccaagtcaa actcttgctc
    26341 atccaagaga acagttaaag tgtgaacagg gcggatgtat tcaaagctat ttccagccca
    26401 gtgcatgctg acagggaaag tcaatgactt caagacatct acaacaccag gaacaatggc
    26461 ttcaactgat tggccaactt cttccttagt gacatagaca tattcttcac ccttaatttc
    26521 acggaattcg atatcttcaa cagtcaaacc tttcccacgg acaaatcctt gagctgcttt
    26581 ggtgaagttt ccatcactat ccaaggcaat tttctttgct ggtcccttga aatcttctgt
    26641 caaatcagac tgtttgtctg ataaaccagt cacacgaaca gccaaacgac gtggtgttga
    26701 gaaggtttga atggcttcaa aagacaggcg gttttccttg aggaaggctg ccattttttc
    26761 gcctagttgt ttttcacttg gtgtgacaac ataggctggt aattcttcaa gaccgagttc
    26821 tactaataag ttttttgtca tgttttttct ccgaaaagta tctttttatt ttccagtttg
    26881 ccttatgtga ttggcacgca agcaaccaac ttcgttgttt cattgctaaa attggagcca
    26941 aaagtctcca attttgccta gtatccttag tttcactaag gataccttca tcactgcggc
    27001 aactggctca gggctcactc tgttcgccca ttttcgtaat ttgtcactct ctttattctg
    27061 cgtcttctgc taggagttta gctcttgttt cttcatccaa aagtgggtag cctaggcgtt
    27121 tgcgttctgc gacaaaggtt ttggctacga cacgggccaa gttacggata cgagcgatat
    27181 agcctgcacg ctctgttaca gatacggcac cacgcgcgtc aagcagatta aaggtatgtg
    27241 aacatttgag aacatagtca taggcagggt gtaccaagcc ttcttctaat gcacgaccag
    27301 cttctttttc aaacttatca aaattttcaa gcaacatttc ttggtccgaa atttcaaatg
    27361 aatattttga gtgctcatac tcaggctgga taaagatttc tccgtatttt acaccatcag
    27421 cccactcgat atcatagaca gagtctactt cttgaatgta agaagccaag cgctccaaac
    27481 cataggtaac ttccgcagtc acagggctag ttgccaatcc accgacttgt tggaaataag
    27541 tgaactgagt gatttccatt ccgtcaagcc aaacttccca accaagacca gctgaaccag
    27601 ttgatgggtt ttcccagttg tcctcaacaa aacgaatatc gtgctccaaa ggattgattc
    27661 ccaatttttc caaagactca aggtaaagtt cttggatatt tgatggagaa ggcttcatga
    27721 ccacctggaa ttggtggtgt tggtagagac ggttagggtt ttccccataa cgaccgtcag
    27781 caggacgacg tgatggctct acataagctg cattccatgg ctcaggtccg atagcacgaa
    27841 ggaaagtgta aggactcatt gttcccgcac ctttttcatt gtcataagcc tgcataagca
    27901 tacaaccttg gtcattccaa aatcgttgca aagtcaaaat aatttcttga aatgttaatt
    27961 tcttagacat tgaatactcc ttaataaaaa ataatttctt gcgacacgag tctacctcgt
    28021 cgattatacg aggcaagacg agttagtact gcgtctagct cagcacccta gtgctgagcg
    28081 tggggcagtc cgactgtaag gaggtctctg ccactgatgc agtgaaatgt caatttctta
    28141 gacattgttt actcctttag tttttatatt tctttttcaa ttaatttctg ctgaacaaac
    28201 caatctaaca agggaaaagt tttttctgta tttgcccata aatgataaga atctaagacc
    28261 gcttgtacac tacctaaatt ttctaccaac ttatctactg tcaaaaagct gcgccagtat
    28321 tcataaaaaa tacttgcata gttcttatca taagtcgaag aaccaaaatc attcaatgaa
    28381 tgccaaccat acttcttctg aaaaagttct acgagagatt gattacaaat tttttccgct
    28441 tgaaattctt cttctgtcaa gaaatacttg cgactaatat attcaaccat cccctcttcg
    28501 aaccagatat aagagtcata accatcaaaa tcatctaaaa aatgctccga ccaatgagct
    28561 aactcatgtc ctacaatctg taagaggaaa ttttcagata aagaatgata gtgactttct
    28621 attgcttgag tttgctgaga acactcgtag tccatcaatt gatacaaata caactctttc
    28681 caaacagcta aatcaggcgc cataaccatt cgtctattat ttgtataggc tggaacagcg
    28741 ctttccctaa taatctgtgt agcagcatta aaatctgacc aaataacggc ttgcggtaaa
    28801 tcacagactg caagttcatt ctttaaaaaa gattgataat ctttcaactt ttcagtattt
    28861 cttactacaa aatcacgaaa tgtagctagt tgactatcgt cttttacaag ataaaggttg
    28921 tccacggctc tcctttcttt cacacaatag actgaataag caaaagaacc acatctgaca
    28981 atcctaggtt gatttaacct aggggcgtca gaaacgcggt tccaccctaa tttattactt
    29041 cattgttttt gaaaatacta cagaaagcgc cagcccttta ttttgcccta cttggctccc
    29101 actatcccaa gctcgcttga agaacgccat aagactttct ttcctgctga ctattatatc
    29161 aaaaattaga ataatgtaca attcttttta tgattttcta gaaatccaca tcatcaactc
    29221 gtggagcacc cgattgaaca gcaatcgttt ttaagttttc tctctcctca tgactcagtt
    29281 caattccaaa gcaatcaaga ttagcttgaa tacgagaggt tgtgacagat tttggaagtg
    29341 gtaaaaatcc ttctgccaag ctccaggcca aggctatctg agcaatcgat tttccgtgat
    29401 ttgctgcgat ttcttgcact tgcttgctat caaatagttc tccctgacca aaaggccccc
    29461 aagcttccaa taaaattccc ttttcacgac agtaagctac gacttgatct tgatacacac
    29521 ctggcgccaa gcgaacttga ttgaccgcag gaacgatagt tgcagtttca agcaaggcat
    29581 ccaaatgatg gggaagaaaa ttgctaacgc cgatagcacg gattttccct tcttgataga
    29641 ggtcttccat cgctctccaa acttccgcat tgcgagtttt ccatgcgtca ttttctctga
    29701 gcggttttgg gttcggccaa tgaatcaaat acaaatccaa ataatccaag cccagttttt
    29761 ctatagattt ttccaaagct tgacgagttt gctcataggt ttgctgacta ttccaaagct
    29821 tggtagttac gaacatttct tcacgtggaa ctccgctatc tttgattgct tgaccaacac
    29881 tttcttcatt ctgataaatc gccgccgtat caatatgacg ataaccagcc ttcaaggctt
    29941 ctaacactgc acgataggct tcttctccat ccttagcctt aaaagttcca aatcccaata
    30001 ctggaatttc tactccatta tttaattgat aggtattcat atgcttctcc ttctatttta
    30061 ttcatcaatt atagcataaa acatttttta agtagtacta tcttctgtaa aaaataagtc
    30121 tgtcaaatat ctaacagacc tattttttct tgcttattca tcacgactat agtacagctc
    30181 atgagctttt aggcgagtat tgagcatctc tggtatggtc acaaaggtat aaccttgatt
    30241 tttcaaatac tcaatgaccc ttggcaaggc attgactgtc ggactgtgaa tatcatgcat
    30301 caaaacgata gagccgttag ctacttgatg ctgaatttct gtcaaaatag atgcttcatt
    30361 tttactcttc cagtccagac tatccacatc ccacatgata aagctcaaat ccaagctatt
    30421 gcgaatatca tctgtaatag caccataagg tggacgcatg agtttagaac tagaacccag
    30481 cactttagtt agcacatcct cagtatcagt aatctgcttt ttagcttcat caagagagag
    30541 ttgcgagaga atcggatggc tccaactatg gtttccaaca acatgacctt cagattttat
    30601 cctcttcacc aagtcctcat tcccagaaac atttttccca agcacaaaga aagtcgcttt
    30661 aatatcatat ttagctaggg tctctaatac ctgcggggtc gttgctggat ttggaccatc
    30721 atcaaaggtt agagcgacaa ctttttgata tttcttatca aagtaagatt ggtacaaggc
    30781 cgcatctttt tcgagtaagt acgaagattg gataacatca aagaaagcag atactggcaa
    30841 ggctatctct tctaaatttt caaccacagg acttggataa aggataatct gactatcctt
    30901 gtaatcaaaa ttccatgcag acaagtcttg gtcagagaag ttttttacaa tctgctcact
    30961 ctggtcttgc tctatttttt tatcctctat gaaggaggtc aactctttta tcagctgttc
    31021 cttagcctta ctagcatctg aaaacagttg gtcaagtgta aaaggttgcc catcttctgt
    31081 taagtgaacc tttcctagac tggtcttttc agtctcttca atcttaaaag caactaaatc
    31141 atagatttgt ttggtcacat tacgattaac gactcccttt aaacctgact cttcttgctc
    31201 tgtatagtag aaaacaagat tgtccttact ttctagcttg tccttaacat cttgatttat
    31261 cagctcccta acagaggaaa tcactttctc cccttggaga ggataatagg caatcacttc
    31321 ggcttgcccc tgacgaaaat gctccttctg atttccctca ctcaattgat catctttctc
    31381 ttttttgagc gattcaatct tttgctcaaa acttttttgc tggtagatct taaaagcaat
    31441 aaatccgcct aataggcaaa tagaaattgc taaaatacca atcaaagcca ataatacatg
    31501 tctcgttttc ccgtgtctgc cacgtcctag tctactttta ttcatattta tatcataaca
    31561 aatttgagca ataatttcaa tgatacaatt tggcaatcca caattcctct agcaagccaa
    31621 agcatcttac atcaactcca acatccgtat ctgtagagat tatgtagttt tctatctatg
    31681 gaatttctag tagattgaag ctagaatagt agacctatac ttctaaaaca ttgttagaaa
    31741 tcgatttgac tgtcctgatc gatttgtcct gttctcattt cattttacta taaaactatg
    31801 aaaagctagg tcatctgaga agtaattact atcgacaatt gcgatagcgt atactggtgc
    31861 gatttgtttg tagctctggt gggtatcacc ttcacgttgg cgaatttttt ctaggttttg
    31921 attaacctga ctgcacagat aagcccatag gcgattgatg aaaaaattct gatgatgaac
    31981 ctgaatttcg atgataactt ggattccatt atctaactcc gccaagacgt ctatactagt
    32041 atagaaatct tgcgctgagt agggcatgga aggcaagacg tgaatgttac ttccctccaa
    32101 aatcgtcaca ttttttgctg gcaagtccag catatcgcgg ataaattgac aaatcattag
    32161 ttgggctgat acctggatgt ctgagaatcc tccttttcct ccttctatta tagcacattt
    32221 ttaaatctag gtttgctaga ttctatgctt ctatctattt attcggaaaa gaaagctaat
    32281 agcttatttg aaattttctc ctctctgttg gatagtcccg tctatctatg ttataatgaa
    32341 agaaggattt aaaatcggaa aaggagtatt tatgctaaaa ttaggtgtca tcggaactgg
    32401 cgctatcagc catcatttca tagaagcagc ccataccagt ggagaatacc aactggtcgc
    32461 aatctattct agaaaactag aaactgcagc aacctttgct tctcgctatc agaatatcca
    32521 actattcgat caattagaag tcttcttcaa atcttctttt gatttagtct atatcgccag
    32581 tccaaactcc ttacattttg ctcaggcaaa agctgccttg tctgctggta aacatgttat
    32641 tctcgaaaag ccagctgtca ctcaaccaca agaatggttt gatttgattc aaacagctga
    32701 aaaaaataac tgttttatct ttgaagcagc tcgtaattac cacgagaaag cctttactac
    32761 tatcaaaaac tttttagcag ataagcaagt gttaggagca gatttcaact atgccaaata
    32821 ctcttccaag atgcctgact tgttggctgg acaaacacca aatgtctttt cagaccgttt
    32881 tgctggtgga gccctcatgg atttggggat ttatcccctc tatgctgctg ttcgtctttt
    32941 tgaaaaagct aatgacgcga cttaccatgc tcaacagctt gacaatagca ttgacctaaa
    33001 tggagatggt atcctcttct acccagacta tcaagttcac atcaaggctg gaaaaaacat
    33061 cacttccaat cttccttgcg agatttatac aacagatgga accttgactc tcaacacgat
    33121 tgagcatatt cgttcagcta tttttaccga ccaccaagga aatcaagtcc agcttcctat
    33181 ccaacaggct cctcatacga tgactgagga agtcgctgca tttgcacaca tgatccagca
    33241 accagatctg aatctctacc aaacttggct gtatgatgca ggctctgttc atgagctact
    33301 atataccatg cgccagactg ctggcattag atttgaggca gaaaaatgaa aaccaaacta
    33361 ccgactgaat ggcaagaact gagtgaccaa ctcggtttcc aagaattcac ccccattcaa
    33421 actcaactat ttgagcccct tcttgctgga gaaaacctcc taggagtgag ccaaaccgga
    33481 actggtaaga ccctagctta tctcctacca agtcttctca gactacaaaa gaaaaaagcc
    33541 caacaactct tgattctagc accaaatacg gaacttgctg gacagatttt tgatgtatgt
    33601 aaaacgtggg cagaagctat cggattgact gctcaactct tcctttcagg ttcaagtcag
    33661 aaacgacaaa ttgaacgtct taaaaagggg ccagaaattc tgattggaac tcctggccgt
    33721 atctttgaac tcattaaact taaaaaaatc aagatgatga atgtggaaac catcatcctg
    33781 gatgaatttg accaattact agatgattct cagattcact ttgtagaaaa aatcactcac
    33841 tacgcacctc gtgaccacca actggtctac atgagtgtca cgaccaagtt tgatcaagaa
    33901 aagattgtac cgaatacacg cactattgat ctctctgatc aaaaattgga caatatccag
    33961 catttctaca tgcaggtaga ccaacgtcat cgagtggata tactacgaaa actggctcat
    34021 gtagaggatt tccgtggtct agtcttcttc aatagcctgt cagaccttgg gaatgccgag
    34081 gaaaaactac agtatcgtga tatattggct gtttccctcg ctagtgatgt taatgttaaa
    34141 tttagaaaag tcatcttaga aaagtttaaa gataaccaac taaccctgct tcttgcaact
    34201 gaccttttgg ctcgtggaat tgatatcgat agcctagaat gtgtcgtaaa ctttgatatt
    34261 cctagagata gcgaaaccta cacacaccgt gctggccgta ctggccgtat gggcaaggaa
    34321 ggatatgtta ttactctcgt cactcatcca gaagaaatca aaaaacttaa aaagtttgca
    34381 agtatccgag aaattgtcct aaaaaaccaa gaactctata tcaaataaag ccccattgct
    34441 ctatacacat ccagtgtatg gagctttttt acaagcaatt caattttata ctcatctgtt
    34501 ttcaaaaagc attctaatcc atctccgatt aacgatggac tttatcacct ccttctccag
    34561 ttcttgtata atatcttgaa gttgattcat gacatcttcc aaagttcgaa aggctttatt
    34621 cttaaatcca cgtttacgaa tctctttcca cacttgttca acggggttta tctctggtgt
    34681 gtatggagga ataaatgcaa agccaatatt agtcggaatt tttaaggtac ttgatttatg
    34741 ccatatagca ttgtccataa cgagtaaaag ataatcatct ggataagctt gtgaaagctc
    34801 ttctaaaaag gcgttcatcc actcagtatt acatccacca gctcttaaga aaaatgattc
    34861 gcctgtatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat agtgactatg
    34921 gacatgtgga cctactccta ttggagacca acaagatccc agtttactga ttctaccgaa
    34981 accagcctca tcttggtaca tcgagcgaac cttatgaaaa cgtctactgg ttttaaagcg
    35041 ctttcttttc ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg
    35101 ctttcttagg atgttctgga cgtggcataa tatttcgcca accatggcgc ttcaacagtt
    35161 gatagaaggc atcacgtgtg taggaacgat ataagcctga aataaggtat tgtaacaaat
    35221 tctcctgcct ctgtagcctt caaatggcgg gcaagaaagg ctttctcttc ctcaactgtc
    35281 atatatgcat ggttacgacc accacgtgtt tcttgaagga gagagtcgag tccgaactcc
    35341 tcatat
//
LOCUS       DAVMBH010000019        34813 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVMBH010000019 DAVMBH010000000
VERSION     DAVMBH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.019"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            78..290
                     /locus_tag="VYP30_001034"
     CDS             78..290
                     /locus_tag="VYP30_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEV1808051.1"
                     /translation="MKFHYVNKWIYIILAIVLGWIGGHHFYAGYNRKGFLYLLFSFTF
                     IPMLLALFQVISALLKTPDSNGKILV"
     gene            310..540
                     /locus_tag="VYP30_001035"
     CDS             310..540
                     /locus_tag="VYP30_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808052.1"
                     /translation="MDYAQDYLDDILVRMAYHSSGIEGNTISLPETVSIILEKSIIVM
                     FNIANTSQRINVNAYTYFQNKNKKVQKKRQKS"
     gene            1432..2598
                     /locus_tag="VYP30_001036"
     CDS             1432..2598
                     /locus_tag="VYP30_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1808053.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKDGSTVYKTVEIKTYAELVENWLETYCHTVKKATLTIIKSRLNNYVL
                     PAFGEYKLDKLTPPVIQKQVNQWAKEYNQLGKGYQEYPQLNSLNKRILKYAVSLQVIP
                     FNPARDIIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLQNGTLDVNKTLNCEKEVTTPKTKSSIRVIDLDNKTVLMLRLY
                     KNRQAQVGREIGLTYEKVFSNSFDEYRDARALRSRLEKHLKLSDCPRLTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHSQISITMNTYSHLSKDNKKNATSFYEKAIEKLKSS"
     gene            complement(2861..3115)
                     /locus_tag="VYP30_001037"
     CDS             complement(2861..3115)
                     /locus_tag="VYP30_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1808054.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(3135..4976)
                     /gene="typA"
                     /locus_tag="VYP30_001038"
     CDS             complement(3135..4976)
                     /gene="typA"
                     /locus_tag="VYP30_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1808055.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            5138..5863
                     /locus_tag="VYP30_001039"
     CDS             5138..5863
                     /locus_tag="VYP30_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV1808056.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMNLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSIGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(5899..6129)
                     /locus_tag="VYP30_001040"
     CDS             complement(5899..6129)
                     /locus_tag="VYP30_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808057.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFRK"
     gene            complement(6218..6598)
                     /locus_tag="VYP30_001041"
     CDS             complement(6218..6598)
                     /locus_tag="VYP30_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1808058.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(6598..6867)
                     /locus_tag="VYP30_001042"
     CDS             complement(6598..6867)
                     /locus_tag="VYP30_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1808059.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLKAEAVLRREHKVELDYIEKNGEKN"
     gene            6931..7839
                     /locus_tag="VYP30_001043"
     CDS             6931..7839
                     /locus_tag="VYP30_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1808060.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(7893..8648)
                     /locus_tag="VYP30_001044"
     CDS             complement(7893..8648)
                     /locus_tag="VYP30_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1808061.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(8669..9598)
                     /locus_tag="VYP30_001045"
     CDS             complement(8669..9598)
                     /locus_tag="VYP30_001045"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1808062.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(9613..10236)
                     /locus_tag="VYP30_001046"
     CDS             complement(9613..10236)
                     /locus_tag="VYP30_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1808063.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(10229..11467)
                     /gene="hflX"
                     /locus_tag="VYP30_001047"
     CDS             complement(10229..11467)
                     /gene="hflX"
                     /locus_tag="VYP30_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1808064.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKFQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTILSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(11460..12344)
                     /gene="miaA"
                     /locus_tag="VYP30_001048"
     CDS             complement(11460..12344)
                     /gene="miaA"
                     /locus_tag="VYP30_001048"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1808065.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVSHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            12465..12635
                     /locus_tag="VYP30_001049"
     CDS             12465..12635
                     /locus_tag="VYP30_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1808066.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(12683..13522)
                     /locus_tag="VYP30_001050"
     CDS             complement(12683..13522)
                     /locus_tag="VYP30_001050"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1808067.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKFAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(13619..14578)
                     /locus_tag="VYP30_001051"
     CDS             complement(13619..14578)
                     /locus_tag="VYP30_001051"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1808068.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(14705..15704)
                     /locus_tag="VYP30_001052"
                     /pseudo
     CDS             complement(14705..15704)
                     /locus_tag="VYP30_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(15754..16371)
                     /locus_tag="VYP30_001053"
     CDS             complement(15754..16371)
                     /locus_tag="VYP30_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1808069.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(16372..18093)
                     /gene="pabB"
                     /locus_tag="VYP30_001054"
     CDS             complement(16372..18093)
                     /gene="pabB"
                     /locus_tag="VYP30_001054"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1808070.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(18167..23779)
                     /locus_tag="VYP30_001055"
     CDS             complement(18167..23779)
                     /locus_tag="VYP30_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1808071.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTIEVVPDDTKYVDEEV
                     VERQGSKGVQITKTTYETVEGVETDKVLSTTTEVKTPAVPKVVKKGTKPVEGTTVETR
                     EEVIPFETKEQEDDTLKRGTRQVVQKGVEGKKQITETYKTIRGEKTNEAPIVKETVIE
                     QPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVEIKSIKVALKDNT
                     GTVIKEVTVEENNLNATLDNLKYYQGYTLSTTMVYNRGEGEETEMLEDKEVQLDLKKV
                     EIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKTTRLAVSSVEEVV
                     VDGKTLYKVVAKAPDLVQRREDDTLSEEYVHYFEKQLPKVDNVYYSFNELITDMQKNP
                     TGTFKLGADLNAANTPTPSKSYVTGEFKGKLSSVDGQHYTIHNTARPLFNNIVGGTVK
                     NINLNNVNIDMPWADQIASVANVIKGGSLIENVKVKGNVLGRNWVSGFIDKIDSGGRL
                     VNVAFIGNVTSVGDGDKFLTGIVGENWKGYVEKAYVEANIKGKRAKAAGISYWSQNSG
                     DNNAVGRDGAIKKSVVKGSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYG
                     SHDIDTDPYYTGERVNRNFIVDGVSEGKSSYTYSKQQKRIKSISQEEADKKIKELGIT
                     ADKFTIIDPIVNKLNNIKQKADTYKDTQDYKADRELAYRNIEKLQPFYNKEWIVDQGN
                     KVPSNSKLLTTEVLSVTGMKDGQFVTDLSEIDKIMIHYADGTKEEKSVSPKPTSNVEQ
                     VKEYGITDLGDVVYTPNMVVKDRAQLLSDVKAKLDTITLESPEVRAITGNVGALYLEE
                     SFAEVKGNLDKLVKALVENEDHQLNSDEAAIKAFLKKVEDNKAKIMMALTYLNRYYGI
                     EYGDLNIKNIMMFKPDFYGKIPSVIDRLIRIGSQEKNLKGDRTQNAYREIIAGDTGKG
                     DLRSFLDYNMRLFTNDTDLNDWFIHSAKNVYVVEPETTNPDFKNKRHRVFDGLNNNMH
                     ARMILPLLNLKKAHIFMISTYNTMAYSSFEKYGKNTEAEREAFKERINYVAKAQQTYL
                     DFWSRLALPNVRDRLLKSQNMVPTPVWDNQAYAGIKDANRRGYGTDGKVATPIRELFG
                     PTDRWHQINWNMGAMAKVYGKPYEDEQVFFMVTNMLEDFGISAFTHETTHINDRMAYL
                     GGHGHRPGTDLEAYAQGMLQTPDKSTSNGEYGALGINMAYHRQNDGNQWYNPDPDKLQ
                     SREQIDHYMKNYNDALMMLDHLEADAVLPQLNGNTSRWFKKMDRQYRSGNSGHQFDKI
                     RELTEDEKKVAINTIDDLITNNLITKHGAPGDGTYNPTDFRSAYVNMNMMTGIYGGNT
                     STGAPGAASFKHNTFRMWGYFGYENGFVGYASSKYQNAANKENNRMLGDDFIIKKVSN
                     GRFTNLEDWKKEYYKEVKAKGEKGFTAIEIDGKQITNYAELKVLFDKAVEADLAGGGT
                     AKTVELKSKVFKALLKNSDGFTGNLFKA"
     gene            complement(23801..24364)
                     /locus_tag="VYP30_001056"
     CDS             complement(23801..24364)
                     /locus_tag="VYP30_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1808072.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            complement(24480..26171)
                     /locus_tag="VYP30_001057"
     CDS             complement(24480..26171)
                     /locus_tag="VYP30_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1808073.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(26168..26905)
                     /locus_tag="VYP30_001058"
     CDS             complement(26168..26905)
                     /locus_tag="VYP30_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808074.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(27263..28375)
                     /gene="msrB"
                     /locus_tag="VYP30_001059"
     CDS             complement(27263..28375)
                     /gene="msrB"
                     /locus_tag="VYP30_001059"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1808075.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEIMLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(28386..28952)
                     /locus_tag="VYP30_001060"
     CDS             complement(28386..28952)
                     /locus_tag="VYP30_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1808076.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(28972..29682)
                     /gene="ccdA2"
                     /locus_tag="VYP30_001061"
     CDS             complement(28972..29682)
                     /gene="ccdA2"
                     /locus_tag="VYP30_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1808077.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(29893..30753)
                     /locus_tag="VYP30_001062"
     CDS             complement(29893..30753)
                     /locus_tag="VYP30_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1808078.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(30932..32986)
                     /locus_tag="VYP30_001063"
     CDS             complement(30932..32986)
                     /locus_tag="VYP30_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1808079.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLILPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     ERGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(32998..33252)
                     /locus_tag="VYP30_001064"
     CDS             complement(32998..33252)
                     /locus_tag="VYP30_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808080.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(33245..33802)
                     /locus_tag="VYP30_001065"
     CDS             complement(33245..33802)
                     /locus_tag="VYP30_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1808081.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(33786..34742)
                     /locus_tag="VYP30_001066"
                     /pseudo
     CDS             complement(33786..34742)
                     /locus_tag="VYP30_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
BASE COUNT        10228 a         7738 c         6342 g        10505 t
ORIGIN      
        1 ataataaaaa taatattagc aataataacg aaataccaca aacaaaaatt tttgatgcca
       61 aaaccaaagc taaaaatatt aaatttcatt atgtcaataa gtggatttac attatattag
      121 ctatcgtttt aggttggata ggtggtcatc atttttatgc aggatataat agaaaaggat
      181 ttttatatct actattcagt ttcactttta ttccaatgct tcttgcactt ttccaagtaa
      241 tttcagcatt gttaaaaact cctgattcca atgggaaaat tttagtttaa ttttacagaa
      301 aggagaatca tggactacgc tcaagactac ctggacgata tactggtacg catggcctac
      361 cattctagcg gtattgaagg gaacactatt tccctacccg aaaccgtcag cattatctta
      421 gaaaaatcca taatcgtaat gttcaatatc gccaatactt cccagcgaat aaatgtcaat
      481 gcctacactt attttcaaaa taaaaataaa aaagtacaaa aaaagcgaca aaaaagttga
      541 tttttaataa aaaaacgata gagttatatt agaaagtcgc ttgtaattct gatatgtctg
      601 cgtatttttc gtaagttgcc tattgggtaa cctgctatca gttaagggct tttatatttt
      661 acaaaaaaat cagtgtatcg acttattatg ttggtacact tttcttttta ctacactagt
      721 tttctacaac aaaaaaaaag acaagctagc tgctgctgac ttgtctaata tcgcctgaac
      781 tgaaataacg ggaaagattc aggcggttac atgactagtt taccatatta tccagaaaaa
      841 caaaaaaggt aagtcaatac cctgtcatca ggctataact ctctaatgaa gtataatgcg
      901 gtataattta gacaattttc aacactttgg cattttagaa acgcttaaag cgctctaaac
      961 aatatcaaaa aaaataaaac tcttgaaata ttggggcttg tatgctagaa tgaaagcata
     1021 aagggaaaaa cagtgcttct agcatatgta actaaaaagc cccaccgtta cagcgatggg
     1081 gttttttgct accctcttaa agggttaaat gctacttgct acgtctcttt atccatagct
     1141 tgaaaagctc agataagacg ttaacaagta acggagctag aaaaagggaa aacaactcta
     1201 gcatatataa cacctccctt ctctaaattg aggaggcgaa aacattatat caaaaacacc
     1261 catcacaaac aagcccatat aagtcccata tctgccttat tcccttttct ggtacaattt
     1321 accgtctgac taattaaaat cgaaaatagg ggtattctcg tagcccctcg catggtataa
     1381 actcaaaatc ttttctaatt gcttgcctgc tgatggaaga ggagtaaaac catgaaaata
     1441 acagaataca caaaaaaaga cgggtctaca gtctatcgct ctagcgtcta tcttggtatc
     1501 gataccgtaa caggtaagaa agtcaagacg actatatcag ggcgaaccaa gagagaactc
     1561 aaagccaaag cgctacaggc tcaaatagat tttgaaaaag acgggtctac agtatataag
     1621 acggtggaga taaaaactta tgccgaactg gtggagaatt ggctggaaac atactgccat
     1681 acagtcaaaa aggcaacact tacaataatc aagagtagac taaataacta tgtacttcca
     1741 gcctttggag aatacaaact agataagcta acacccccag ttattcaaaa gcaagttaat
     1801 caatgggcaa aagagtacaa tcaactaggc aaaggttacc aagagtatcc gcaacttaac
     1861 tcgctaaata aacgaatact taaatatgcc gtatccttgc aagttatccc cttcaaccca
     1921 gcccgtgata ttatcgtgcc acgtcgtaag gaaaaagaag ggcaaaaact gaaatatctg
     1981 gatgatgata acttaaaaaa attcttgact tacctggagc agctgccaaa cacttacaaa
     2041 aatttctacg atacggtgct atataagacg cttttagcga ctggtttgcg tattcgtgag
     2101 tgtttagccc tcaaatggtc tgatattgac ttacaaaacg gtacactaga cgtaaataag
     2161 actctaaact gtgaaaaaga agtcactacc cctaaaacta aatcaagtat tagggtaatt
     2221 gacttggata ataagacggt gctcatgctg cgactttaca aaaatagaca agcgcaagtt
     2281 ggtagagaaa taggcttgac ttatgaaaaa gtattttcta attcctttga cgaatataga
     2341 gacgctaggg cgcttaggtc aagacttgag aaacatttaa aactttctga ctgccctcgt
     2401 ttaacgttcc acgctttccg ccacactcac gctagtatct tgctcaatgc cggactgcct
     2461 tacaaagaaa tacaaacaag gctagggcat tctcaaatat caataaccat gaatacatat
     2521 agccacttgt ccaaagacaa caagaaaaac gctacttcat tttatgaaaa agccattgaa
     2581 aaattaaaaa gttcctaaaa agtccacaaa ttttataaat cggttatgaa tcaagccaca
     2641 aataccgcta tactagggaa tttaccccct atacttgaaa taaagcgcat ttcaaaataa
     2701 tatgcaacca gtactaacca aatataaaat agatgccatt aacgaatttt attcaagttt
     2761 ttcccattca tactatacaa gcaaaagaga tggtgttaac taaaaagcaa ttcaaactat
     2821 tataaaattc ctagcaaaaa gagagccgaa actctctttt ttatcttctt ttactttttt
     2881 tgactggcat gagtgtgatg tctctcacac taaagtaagc taggatcaac atggctattg
     2941 ctaggaatat ttctgttggt aattgaaaaa ttttcagaaa agatagaacc aataaaatca
     3001 agagtgccac taaaatacat accatagcga cgatattgac tgtcccttta atgctttctg
     3061 gtgtcgcaaa tacatagagt aggagcagta aaattcctag gactaaatag accatctttc
     3121 tctctttcta gctcttattc agctgatttt ttcttcttgt tagctttctc acgctctgct
     3181 ttgttaagga tttgtttacg caaacggata gactcaggcg ttacttccat gtactcatcg
     3241 tcgttcaaga actcaagaga ctcttcaagt gtcaagatac gaggcgtctt gataacagct
     3301 gtttggtcct tagtagctga acgaacgttg gtcatttgtt ttgccttcgt gatgttaact
     3361 gtcaagtcat tttcacgaga gttttcgccg atgatcattc cttcataaac ctcagtacct
     3421 gggttgacaa agatcgtacc acgttcttcg atagacatga ttgagtaagt tgtagcctta
     3481 ccagcatcga tagaaacaag ggcaccacgg tgacgtccac caatttcccc tggaatcaat
     3541 ggcaagtact ggtcgaaggt atggttcatg ataccgtaac cacgagtcat tgacaagaac
     3601 tcagttgagt atccaatcaa accacgcgct ggaacaagga agaccaaacg agtttgacca
     3661 ttaccagttg aaatcatatc caacatttca cctttacgtt cagaaaggct ttggataaca
     3721 gacccttggt attcttctgg agtgtcgatt tgtacacgtt caaatggttc acatttaaca
     3781 ccgtcgattt cttttacgat aacttctgga cgagatactt gaagttcata gccctcacga
     3841 cgcattgttt cgataaggat tgacaagtgc aattctccac gtcctgaaac agtccattta
     3901 tctggtgaat cagttgggtc aacacgaagg gaaacgtctg tttgcaattc tgcctgcaag
     3961 cgttcttcca ccttacgaga agttacccat ttaccttctt taccagcaaa tggtgagttg
     4021 ttgaccaaaa aagtcatttg aagagttggc tcatcgatgt gtaggattgg aagagcttct
     4081 actgcatctg tcggagtgat ggtttcaccg acaaagatgt cttccatacc tgaaacggca
     4141 atcaagtcac ccgctttggc ttcttggatt tcacgacgtt ccaaaccaaa gaaaccgaag
     4201 agttttgtaa cacggaagtt tttagttgta ccgtcaagtt tagaaagggt aacctggtcc
     4261 ccaaccttaa ctgtaccacg gaagacacga ccgataccga tacgtccaac aaagtcattg
     4321 tagtccaaaa gtgacacttg aaactgcaaa ggctcatctg agttatctac tggagctggg
     4381 atatggtcga taatcgtgtc aaagattggt gccatagtcg cttcttggtc agctggatca
     4441 tctgacaatg aagaagttcc gttgatcgct gaagcataaa ccactgggaa atcaagctgg
     4501 tcgtcatctg caccaagctc gatgaaaagt tccaagactt catccactac ttctgctgga
     4561 cgagctgatg gcttatcgat tttgttaaca accacgattg ggacaaggtc ttgttccaag
     4621 gcttttttca atacgaaacg agtttgtggc atggttcctt cataggcatc tacgaccaag
     4681 acaacaccgt caaccatttt catgatacgc tcaacttctc caccaaagtc cgcgtgtcct
     4741 ggtgtgtcca taatgttgat acgagttccg ttgtaagcaa cggcagtgtt tttagcaagg
     4801 atggtaatcc cacgctcttt ttcgatatcg tttgagtcca tagcacgctc tgccaattca
     4861 gtacgtgcat caagcgtttc tgattgtttc aataattcgt caaccagggt tgttttaccg
     4921 tggtcaacgt gggcgataat cgcaatgtta cggatatctt ctcttaattt tgtcatgatt
     4981 tcctctataa tattcaaaat ttattttcta actgaacgat tataccataa tttcaaataa
     5041 ataacataac tcaagcaagt gtaaatgttt tcactccgct tttcttttca cgtcaagcct
     5101 tttcaaagca agcgacttat gataagatag gcacagtatg cgtttagata atttattagc
     5161 ccaagaaaaa gttagccgaa aggccatgaa gcaagcactc ctcagagggg aaattctagt
     5221 cgatggttgc ccagcccgct ccctagctca aaatatcgat acaggactac aagaactcct
     5281 ttttcaggat cgaatcattc aaggctatga acacacctat cttatgcttc ataaacctgc
     5341 tggtgtcgtt acagccaaca aagacaagga acttccgacc gtcatgaact tgcttccatc
     5401 tgacatccag tctgacaagc tctatgccgt cggccgactg gaccgagata caacaggact
     5461 ccttctcttg accgataacg gtcccttggg cttccaactc ctccatcccc aatatcatgt
     5521 cgataagact tatcaagttg aggttaatgg acttctaaca cctgaccata tccaaacctt
     5581 tcaaaaagga attgtctttt tagatggcac tatctgtaaa cctgcaagac tagagattct
     5641 atcagcaagt ccttccctca gtcaagcctc tatcaccatt tcagaaggaa aatttcatca
     5701 aatcaagaaa atgttcctct cgattggtgt taaggtgact aacctcaaga gaatccaatt
     5761 tggggacttc acattgaacc cagatttagc agaaggtaac taccaccctt tgaaccaaaa
     5821 agagttacaa atcattaaaa actatttaga gatgagtcga taaaacaaaa aaagctttaa
     5881 aactaaagct tttttctttt atttccgaaa aattaaggcg attgctacaa tccagttaac
     5941 tacagaaatc acaattccta agatattaag aatcttttct attttatagt ctaattgtga
     6001 ctctttttgg tatgaaatag ccaagaccaa tcctatgata cccaaaatca ggcctacaat
     6061 tggaaataac aaaccaagaa taatcgacaa gatacccaca aaaagtggat ttttcttctt
     6121 ttctttcatg ttctaagaac tctttaaatt ttatacaaat taattatact ataaaacaat
     6181 atcttcatcc tatcattcga ctaatttgga aataaggtta gctagtcttc actttccctt
     6241 tccaagaatc caagccataa gaaaggatat aaatctcaga aaaaccttgt tttttcaagt
     6301 aaagagctgc atttgtaact cgttgcgcac gttggttttc gtagagaagg acaggtttat
     6361 ctttacgaag ggctgcaaga ctagttttca actgacttga aggaatattg cgtgcaccaa
     6421 ggatatgttt tctgtggaat tctgctgggt cgcgcaaatc aatcaattga cctgtacgaa
     6481 tcaaggcttc aaactcctca ttgtccacaa ttttagccgc acggcgaata cgaagatagt
     6541 taaagcccat ccacgccaac attgctagta taagtgccca caaaatccaa gtaaccatta
     6601 gttcttttct ccatttttct caatataatc caattctacc ttgtgctctc tgcgaagaac
     6661 tgcttctgcc tttagatagt ctaatttatc catcaaccct gcatcgtaaa tccgagatag
     6721 ttccaacttc atcagttcaa tatcatataa gcgttttccc atgtaaacaa taataccaaa
     6781 tcgtttgagg aattgctgca catcatagaa tgttttcata agactcattc tagcaaaatt
     6841 ttgtgttttt ttcaagaaga gactcacaca atgctcctta ttttcctatc ttctttagcg
     6901 attctaaggc aagtatggta caataaaaac atgagaattc aacaattaca ttatattatc
     6961 aaaatcgtcg aaactggctc catgaatgag gcagccaagc aactctttat cactcagcca
     7021 agtctctcca atgcagtgcg agatttggaa aatgaaatgg gcattgagat ctttatccgc
     7081 aatcccaagg gaatcacctt gacccgtgat gggatggagt ttctctctta tgcccgtcag
     7141 gttgtcgagc agacccagct tctggaggaa cgctataaaa atcctgtcgc ccaccgcgaa
     7201 ctatttagcg tttcgtctca acactatgcc tttgtggtca atgcctttgt ctctttgctc
     7261 aagaaaagcg atatggagaa atacgaactc ttccttcgtg aaactcggac ttgggagatt
     7321 atcgacgacg tcaagaactt ccgcagtgag gtcggggtcc tcttcttaaa cagttacaac
     7381 cgtgatgttt taaccaagat gctggatgac aatcacctgc tagcccacca tctcttcaca
     7441 gcgcaaccgc atatctttgt cagcaagacc aaccctctgg caaagaaaga caaggtgaaa
     7501 ctgtctgatt tggagaattt cccttacctc agctatgacc aagggacgca caactccttc
     7561 tacttttcag aagagattct ttctcaagaa caccacaaga aatccattgt ggtcagtgac
     7621 cgtgccaccc tctttaatct cttgattggt ttggatggtt ataccattgc gacagggatt
     7681 ttgaacagca acctaaacgg agacaatatc gtttctatcc cactggatat tgatgacccg
     7741 atcgagctgg tctatatcca gcatgagaaa accagcctat ctaagatggg cgaacgcttt
     7801 atagactatc tcctagaaga agttcagttt gatagttgag aaatgataag aaccaatatg
     7861 taggctagca acaacctgca cattggttct ttttacttat aattaaaagt ttcccctgcc
     7921 aacttatcag ctagcttagg aaagagggta taaaacttat gagctaggtt caacaaaatc
     7981 gggagattga gttctcgttt gttttttcct ataatcttga caatcttttt agccactgca
     8041 tctggttcta gcaggaagcg gtcaaccgat ttaagataag ttccatctgg gtcagcttgg
     8101 tcaaaaaatc ctgttcggat tggacctgga ttgactgttg tcacatagac tccatagggc
     8161 ataagttcga gtcgcagagc atttgaaaaa ccaatagccg caaacttggt cgctgagtaa
     8221 agactagact tgccagtagc tattagacct gccatgctga cgatgttgat gatatgccct
     8281 ttgctgcttt ccttcatacg agccgcaagg tgacgagaca gattcatcag ggcaaaggta
     8341 ttgacctcaa acatctggtg aatgtcttta tcagcaattt ggtcaaatcc ctcaaaaatc
     8401 ccgtaaccag cgttgttaat caagacatca atcttgccat agcggagata aagatcagtt
     8461 accagagctt ctagggctga atcgtcggta atatcaattt caatcaattc tgcatgggaa
     8521 taatttccgt agagttgggc taatttttcc ttatttctac caagcaagat gagttggtca
     8581 ttgggcagga gtttgaccat ttcttgagct agaccaccgc tagctccggt aatgagaata
     8641 gtaggcatac ttatcctttc tgtgactgct agatttccac ttcttccaag tctttgacca
     8701 catggacatt ttcaaaaatt gtggcagcgt ctttcttgag tttgctaata tcttttgaga
     8761 ggaaacgggc actgatatgg ttgagtagga ggcgtttggc acctgcttct accgctactt
     8821 gtgcagcttg catattagtt gagtgaccat ggttacgagc aattttttca tcacccttgc
     8881 cataagtgga ctcatgaact aggacatctg cattgacagc cagacgcaca ctggcatccg
     8941 tttttcgagt atctcctaaa atagtgataa tcttacctgg acgtggcgct gagatatagt
     9001 ctgctgcctt gatttcagtt ccgtcttcca aaacaagatc ctggccgttt ttgattttac
     9061 caaaaagcgg gccgaacgga acaccagcag ccttaagttt ttcagcatcc agcgtccctt
     9121 ctagatcctt ttgcatgaca cgatagccaa cacagaaaat agtgtggtcc agctcctctg
     9181 catacacagt gaatttatcg gtttcaagaa ttttacctag agaatcttgg tcaaactcat
     9241 ggaaatgaat gcggtagggc agacgagaac ctgacacacg aaggctggtt aagacaaatg
     9301 acttgattcc ttgaggtccg tagatttcca aatctgtctg ctcttcattg gcctgaaagg
     9361 cacggctaga aaggaaacct ggcaaaccaa aaatgtggtc tccatgcaga tgggtaataa
     9421 agattttgct gaccttacgt ggtcgaattg tggtttccag aatgcgattt tgcgtacctt
     9481 ctccacagtc aaagagccaa acttcgttaa tctcgtccaa aagtttcagg gcgagacttg
     9541 aaacgttgcg ggctttagag ggctgaccag cccccgttcc taaaaattga atatccattc
     9601 gatactttct aattaatcaa tatataacat ggctgtgcgg ttttccgatc ggaaatagcg
     9661 tttgccagaa aaagcagcag cttcttgcaa taaatcctct tggctgtagc ctttgagacg
     9721 ttttcgacca tcagccaatc tttccaaatc agtcaaagct gtgagacttt ctaggctgac
     9781 aacttcctcg tccttgacag gcttcatgta aatcttacca gactcttcaa agactaattg
     9841 atgggagaaa atttgcgcaa tttcaaagag caagtcatcc gagattttct cctcattttc
     9901 agagaaaatc cgaccaaagc cgtcactctc ataacaaaaa ccaaaggatt taccagacag
     9961 attaagccga ataaaaggct tattttctag ggtgaaactt ggctcagtat tgtaaagatt
    10021 cagttcctga ctgagttctg caaaataatc cgtcgcagcc tgaggacttt ttttctgata
    10081 gagttctgca aagtaggcat taacaacact tggcggaggt gtaataagtg ttaactgctc
    10141 ctgctctgtt ttaccagcta gaagctgatc cagatagacc ttgtccagac ttgtataacc
    10201 tccatacttt agagccaaag ttttaatatc agtcataaaa ttcttctaac ctccatttat
    10261 ttttctcgga aatgtagcct gtaatcactt cgccgtcttc ctgataatca cgttcttcca
    10321 gaattgcaac actctctaaa tcatgaatct tgtaggactt tgaaaaaggc actcgcaggg
    10381 taaatgcttc aaaaatttcc ttaatcttat ctagcaataa tgcttgcaag ttttcacgac
    10441 tgtcctcaga cttggcagaa atgagggtat atggcgtttg ggtaggcgtg aaatcctcca
    10501 ccaaatccgc tttattataa agcgtcaagt gaggaatatc ttccatgtcc aggtctttca
    10561 tgatggagag aatcgttttt tcatgttcct cgtggtaagg attgctagca tcgataacat
    10621 gaaccagaag gtccacatgc ttgctttctt ccaaggttga cttgaaactg gacaccaact
    10681 ctgtcggcaa atcttggata aagccaacgg tatctgtcaa agttacttgg aggttgcctc
    10741 ccagatgaat actcttggtt gtcgcatcca gagtcgcaaa gagctcatct gcttcatact
    10801 gggtcttact ggtcaagatg ttcatgatag ttgatttccc agcattagta taaccaatca
    10861 aaccaatctt aaaagtgcta gactccaaac gtttttctct gacagtcgca cgatttttct
    10921 caaccacctt aagctggcgc tcgatatccg tgatttgatt gcgaacgcta cgacggttca
    10981 gctccagttg gctttcacca ggaccacggg aaccaattcc ccctgcctga cggctgagca
    11041 taatcccctg accaaccaag cgaggcaaga ggtatttgag ttgggctagg tggacttgga
    11101 acttcccttc atggcttcga gcccgcatgg caaagatatc caaaatcaac tgcatacggt
    11161 caatgacctt aacaccgaga acttcctcta gattgacatt ctgccttggg gtcagacggt
    11221 tgttgacgat gacagtagtg atttcttctg catccaccat aagcgcaatc tcttccaact
    11281 taccagagcc gacgaaggtc ttggaatcat atttttcacg tttttgtctg tagctatcta
    11341 caacgactgc ccctgccgtt ttcgctaaac tagccaattc ttccatggag aggtcaaaac
    11401 tgtccatacc ctgcaattcc acaccaatca gcaggactcg ctcctctttt ttctccgttt
    11461 caatcatcta aaaactcctc tatctggctt aaaatgcggt cttgtacacc agattctcca
    11521 atctgataaa aggtgacctg catgcgatta cggaaccagg tcagctgacg cttggcaaaa
    11581 cgacgggtcg cctgtttgag actctcacta gcttcctcca aggtctgctc tccacggaaa
    11641 taaggaaaga gttccttata gccaattcct ttagcagcct gtacattagg ggaatggtca
    11701 aacagccact tggcctcatc caaaagccca gcctcaaaca tcaaatccac tcggtggttg
    11761 atacgctcat aaagttgact acgttcatca tccaagcaga taatcagcgg ttcatacaag
    11821 gtctcttgat tttccaaatc ctgaccaaaa tgggcaattt ctaaggcacg catagcacga
    11881 cgacgattaa actggggaat ctcaaggcct gcttgatcca ccaaatgggc taattcctca
    11941 tctgaatatg gctccaaact agctcgataa gctaaaatct cctcatgagg agtctcccca
    12001 cctaggtggt aaccttctag caagctctgg atataaagtc cagtcccacc ggcgataatg
    12061 gctagcttgc cacggctgtg aatatcctca atagtcatct tagcttctga aacaaaatca
    12121 aaagccgagt aagactcggt tatctctcta acatcgatta aatgatgaga aacagctgcc
    12181 tgctcttctg gactagcctt ggccgtccca atatcaagtc ctcgatagac ttgttggcta
    12241 tctccactaa ccacttcgcc attaaaacgc tttgcaactt caatagctag agccgtcttt
    12301 ccaacagcag tcggtccaac aatcacaatt atttttgttt tcatcttttt tccttgaaaa
    12361 attcccattt tttcgttact attattataa cacaaaaagg tcagtcagaa aaatgtgacc
    12421 tcttgaggag gctggctgat tgagaatata aaggaggaag actcatggct aaaggattcg
    12481 ctaaaggtct tgtaacaggt gtcgcaggaa ctgtcgctgc cgttgcaggt gcagtatacg
    12541 catttaaaaa gaaagtaatc gaaccagaag agcaaaaagc agctttcatc gaagaaaacc
    12601 gtaaaaaagc agctcgtcgc cgcgtatcac gttaagaaac aaaagaagtt gggattattc
    12661 tcaacttctt ttttctattc ttttaaatag ctaggtcaaa cttcaactgt ggcttaacag
    12721 ggtcataatc caccaactca aaatcttctg ctttgatatc aaagaaatta gtcccatcag
    12781 gaacatttaa aaccaagcgt ggttggcagt ttgacggctc ccgacggagc aattcctgag
    12841 cttgttcaaa ttgattatca tagatatgga ggttgttgat gaagtagaag aacttcccaa
    12901 ccttccagcc aaaatgtttg gcaatcatca tctgcaaagc cacatactgc atagcgttga
    12961 tgtggtgggc caccagcata tcattggagc gctgggtcaa ggtcgcatcc agatagattt
    13021 ccccatcaac acgccggaca tcaaacatgg tctgaaaggc gcacgggagc agcccatctg
    13081 tttcttcgaa agcttggtaa tcccagagcg aaataatatt gcggcggttc caaggattgg
    13141 tttccaactg tttgagaagc ttattgataa tgtcgtgttt cttaacaacg gcaccatagc
    13201 gctcaccaat ggttcccgtg tctccaactt cccagtcatt ccagtagtga acattgtact
    13261 tgtcattaag cacttctaag ctatttgact ggtcttggta aatccagaga acttctttga
    13321 tggcgaattt gattgcaatg ggacgcaagg ttgtgatagg aaattctcct ttagataagt
    13381 cgtactcgga aaaggcacca gttacatact tagaattagc aacagtccca tccttgtact
    13441 taggacgagc ctgctctgag aaaacacctt cctttagaat gcgttcaata ttctctttaa
    13501 aaatcgtatc tgcttttgtc atttcgtttc acctcattca ttgtcctaac tagtatagca
    13561 taaaaaataa aagaggaaca ttactaactc taggttagca ttttcctctc tcattatctt
    13621 attgcaatac aagtgatgct gctccgataa ctccagcgtc atttcctaga gttgcaagag
    13681 ctaatttagt agatgtgcgt acttgtggga aactattttc atcgtaaact ttttgaacac
    13741 cttgtagaag gaattctccc gcagctgaca caccaccacc gatgacgatt gttgatgggt
    13801 ttaggattga accaatgtta gcacaagcga ttcccaagta acgtgagaag ttacggtaaa
    13861 caatcaaagc aaggtcgtct ccttcttttg cgagatcaaa gacagtctta gcagttactt
    13921 cttctccgtt atcaatcaag cgtttcaagg ctgcatcgcc ttcgtattca tcggcatagc
    13981 gacgagtcaa gttgacaatc cctgttgctg aagcaactgt ctcaaggcag cctttcttac
    14041 cgcaagtaca tgcgattggc tggtcaaagt caacagtgat gtgaccaagc tcacctgctg
    14101 caccagcaac accgtgaagc aatttgcctt ctgcgacgat accgccacca acaccagtac
    14161 cgagtgtcat aaagacaacg tctggttggt tatctccagc acccatccag cgctcaccaa
    14221 gagctgctac gttggcatca ttatcgatga aaaatggaat gcccaaagct ttttcaatct
    14281 tttgtttgat tggttgaagg gttttccagt tcaagttgta ggcaccgata acagtccctt
    14341 tttcacggtc aaccacacct ggtgatccca ttccaatgcc ttggaagtcc gctgctgcca
    14401 atccaagcaa gtccaaacga tgttgaatag actcaatcat atcatcaacg atatgacttc
    14461 cctcatccaa aatgtttgtc ttgattgacc attttccttg gatttctcct gctgttgtta
    14521 agattgcaaa tttgatagaa gttccaccaa ggtcaatccc aataatcttt tgactcatca
    14581 tattctcctt tttcattgtg tagtaattga aaatgcttac agtactagta tatcaaaatt
    14641 cattcactta tgcaaaggtt tgcgtaagtg aattataagg aattttttcg cctaccagta
    14701 tctgttaatc atctaaatga tcaatggcat attgagctgc atcatttgaa aatttatcaa
    14761 aatcagaagt taattgtcta tacatacgtt ttttttgaca tgtggaataa cgaattataa
    14821 ctttttgcct ttcctaaagc agcagaatat tcactattgc tatcattact agaagaagct
    14881 gtacttgctt gaccttcctt ccaaactccg tcagcgccaa cataataacg tccaccatca
    14941 acccattcat tgacagccat tttaccatcc gattttagat agtaatttcc ttgccatgta
    15001 ctgtaagcat aagaaccatc tgatgtcaaa taataccaag cttgataggt ggcaacataa
    15061 acccattcac ctttagccat tttaccatct gatttcaaat agtagtttcc ttgccatgca
    15121 ttgcgagcat atgaaccatc tgatttcaag taataccatg cttggtaaga agaatcataa
    15181 acccactcac cttgtgccat tttaccgttt gatttaaggt aataagctcc ttgccatgca
    15241 ttttttgcat aagaaccatc tgatttcaaa taataccaag cttgataaga agagtcataa
    15301 atccattcac tctgtgccat tttaccatca gctttcaggt aatagcttcc ctgccatgca
    15361 tttttcacta gatttccatt tccatcaaag tagtaccaag cgccgtcctg cttaacccaa
    15421 ccacttgttg ttgctgaact tgtgttgatt tgaatagccg ttgactgttt tgctttaaaa
    15481 gcacccttag gagcattttt caattcgcaa gccacaccat catgatcacg gtctaacttg
    15541 gcagaataac caggttctcc ctcgtgaata tccgaatagc cattcgccca agcttcctta
    15601 cagctcgaaa aatggatgtt ttcttccgcc aaaactggtt gtgaaaacaa ggctaaaatt
    15661 ggcaacgtca ccagactcat ttttaaaaat agacgtttat tcatttcttt ctcccataat
    15721 tatgatatcg atttcaatat tattttatca aacttatttc agcaattcaa ggaaacttct
    15781 ggtcttttct acaaactcct ttggttttgc cttattcaag acatgagggc catcaggaat
    15841 gatctgaaac tgcgaatctg ttaacagtct atggagagct ttcatagaac taagattcgg
    15901 tttatctttg ctgccacaaa ttagtaaggt tggataggag caagtccctg ctatatccgt
    15961 taaatcaagt gtcttcaatt cctcagaaac tccgaccata agagtcttgt ctgctccctg
    16021 tttttcaaat actcttttgg gaagtagttt aaaaatcagc aattgaagat aaaataggat
    16081 attccctgct aatttaagcg ggcatcctga cagaatcaaa gctcgaagat ttggtaaatc
    16141 gtaactggaa agttctagtg ccagggcagc acctaaggac aatccaatca aaacaaaagg
    16201 ttctgtctct tgagctaggt gctgataaac tcgctcctta gcttgttgat agttactaac
    16261 tccagaagga aataactcga tagcctcaga aggataatct gtcagtagat tccgaacttc
    16321 tttccaagac tctgctgact gccctaaccc atgcaaaaat atcagtttca tctagttctc
    16381 ctcaaggctt agttcataca agcctctcac tgcattacag ccgtaaatag cttctgcttg
    16441 ggctaaatct gccaaggtca agactttctc ttctacctgt cctgtttcta gcaaatactg
    16501 acggtaaatt cctggcaaga ttccaagtcg gataggcggt gtgtagagtt ttccagcgat
    16561 tttcagaacc aaatttccta tagaggtttc aagcagtttt cctgacttat tgtggtaaat
    16621 cttctcttgt tctcctaggc tcaaatgcgg tcggtgagtg gttttaaagt aggtaaagga
    16681 ttgattcaaa gcagcttcct gaaggcagac ttgggcctga caaaagcttg tactgagagg
    16741 ggttaatact tgacgattga cttctatctc tccagatttg ctaaggctga ttcgcaagcg
    16801 gtaatcttga ttagcttcac aatcctgaca ctcttcctca atcttgtgtc ccaagtcttc
    16861 tgcatcaaaa ggaaaggcaa aataacgact agcttttctc agtctttcca gatgttgatc
    16921 ttcaaacagc aggttcttct ggctgatttc ccctgtcgta atcagttgga agcgggcttg
    16981 tttacgataa agaactgctg ccttttgatg aacctctcgg tattcagatt cccatgtgct
    17041 atcccaagta atccctccgc caactccata aatggcttga cctttgtgaa gttgaatggt
    17101 acgaatggcc acattaaaaa tccgtcgtcc atttggaagc aagagaccaa tcgttccaca
    17161 atagactcca cgcggttgag gctccaagtc cttgataatc tccattgtcg caattttcgg
    17221 tgcacccgtt atggaaccac aaggaaagag tgagcggaag atttcaacaa ggtccacatc
    17281 ctctcgcaac tgactcttga tggtcgaagt catctgccaa acagttgaat actgctctac
    17341 ctggcacaga cgctccacgt gctcgctccc aacttcagaa atacggttca tatcattgcg
    17401 caagaggtcc acaatcatca tattttcaga gcgatttttg ggatcctgtt ccaaccaact
    17461 ggcctgttca agatcttctt ggtcagttac cccacgctga gtcgtcccct tcattggtcg
    17521 tgttgtcaac tcgcgatcat tttgctcaaa aaagagctct gggctcatgg aaatcactgc
    17581 catctcgtca tgttccacat aggcattgta gcccgcctcc tgctctacca ccatacgatt
    17641 gtagatggca aaaggattgg cacttaactt ttgcttgagt tggacggtgt agttgacctg
    17701 ataggtgtct ccctgcctca agtgatggtg tatctgggca atggcctttt catagtctgc
    17761 tgcagacgtc acttcctgcc aatttgaggg caaatcaata tcctcataag tcagaggaat
    17821 aggggaggtc tctaccctat catgaacagt aaagtaaagc aggtactctc ccagtagggg
    17881 atccttgtga actgctaatt tttcctcaaa agcaggggca gcctcgtagc tgacataccc
    17941 caccacataa taaccttgct cttggtagct ttccacttgt gccagcaaat ctgccacttc
    18001 tgctacattt ctcgttttta tctctttgat aggctgggta aaggtgtatc tctcccccaa
    18061 aatcctaaaa tcaatcactg tttttctatg catactttaa gtatagcata aaaaggcaga
    18121 tacagacaaa gctgctctac ctttttactc atctatttaa tacaatctat gctttaaaaa
    18181 gatttcctgt gaatccgtct gaattcttaa gaagtgcttt aaagactttc gatttaagtt
    18241 ctacagtttt agctgttcct ccacctgcta gatcagcctc aaccgcctta tcaaataaga
    18301 cttttagttc agcataattg gtaatttgtt taccatcaat ctcaattgca gtaaatcctt
    18361 tttcaccttt tgccttcact tctttatagt actctttctt ccaatcttca aggttagtga
    18421 atcttccatt tgaaactttc ttaataatga agtcatcacc taacatccta ttattttctt
    18481 tattggctgc attttgatat ttgctagaag catatccaac aaatccattc tcatatccaa
    18541 agtatcccca catacggaat gtattatgtt taaatgatgc tgcacccggt gcacctgtac
    18601 ttgtatttcc accataaata ccagtcatca tgttcatatt aacataagca gacctaaagt
    18661 ccgttggatt ataagtacca tcaccaggag caccatgttt cgttattagg ttattagtaa
    18721 ttaaatcatc aattgtattg attgctactt ttttctcatc ctctgtcaac tcacgaattt
    18781 tatcgaactg atgacctgaa tttccactac ggtattgtct atccattttc ttgaaccagc
    18841 gactcgtatt tccatttaac tgcggtaata cagcatcagc ctcaagatga tctaacatca
    18901 taagagcatc attgtagttc ttcatatagt gatcaatttg ttcacgactt tgtaatttat
    18961 caggatctgg gttgtaccac tgatttccgt cattttgacg atgataagcc atattaatac
    19021 ctaatgctcc atactcacca tttgatgttg atttatcagg tgtttgtaac ataccttgag
    19081 catatgcttc aaggtctgta cctggacgat gtccatgacc accaagatat gccatacggt
    19141 catttatgtg agttgtttca tgtgtaaagg ctgaaatacc aaagtcctct aacatatttg
    19201 ttaccatgaa gaaaacttgt tcatcttcat atggttttcc ataaacttta gccatagctc
    19261 ccatattcca attaatttga tgccatctgt ctgttggacc aaataactca cgaattggtg
    19321 tcgctacctt accatctgta ccatatccac gacgattagc atccttaata cccgcataag
    19381 cttgattatc ccatacaggt gtaggaacca tattttgact cttaagaagt ctatcacgaa
    19441 catttggaag tgcaagacgt gaccagaagt ctaagtatgt ttgttgagct ttagctacat
    19501 aattgatacg ttccttgaac gcttcacgtt cagcttccgt atttttacca tatttttcaa
    19561 atgaactata agccatagta ttataggttg aaatcataaa gatatgtgct tttttcaagt
    19621 tcaataatgg taaaatcata cgtgcatgca tattattatt cagaccatca aaaacacgat
    19681 gacgtttatt tttgaaatct ggatttgttg tttctggttc tacaacataa acatttttcg
    19741 ctgaatggat aaaccagtca ttaagatctg tatcatttgt gaagagacgc atattataat
    19801 ctaagaaact acgtaaatca cctttaccag tatctcctgc aataatttca cgatatgcat
    19861 tttgggttct atcacccttc aagttctttt cttgcgaacc aattcgaatt aatctatcaa
    19921 taacacttgg tatcttgcca tagaaatctg gtttaaacat cattatattc ttaatgttta
    19981 agtcaccata ttcaatacca taataacgat tgaggtaagt aagtgccatc atgattttag
    20041 ctttattatc ttctactttc ttaagaaatg ctttgatggc tgcctcatca ctatttaact
    20101 gatgatcttc attttcaaca agagctttta ctaatttatc aagatttcct tttacttctg
    20161 caaaactttc ttctaagtat aatgctccaa cattacctgt tatcgcacga acttcaggag
    20221 attcaagagt aatcgtatct aatttcgctt taacatcact tagtaattga gcacggtctt
    20281 taaccaccat atttggtgtg taaacgacat ctcctaaatc tgtaatacca tattctttta
    20341 cttgttctac gtttgatgta ggcttaggtg atacagattt ttcttctttt gtaccatccg
    20401 catagtgaat cataatttta tcaatttctg ataagtcagt cacaaattga ccatctttca
    20461 tacctgtaac agataatact tctgtagtta ataatttaga atttgatgga actttattac
    20521 cttggtctac aatccactct ttattataga atggttgaag tttttcgata ttacgataag
    20581 caagttcacg gtctgctttg taatcttgag tatctttata agtatcagct ttttgtttga
    20641 tgttgttaag tttatttaca attggatcga taattgtaaa tttatctgct gtgataccca
    20701 attctttaat tttcttatct gcttcctctt gagatattga tttaatacgc ttttgttgtt
    20761 tagagtatgt atacgaagat ttaccttcac ttacaccgtc aacaatgaaa tttctattta
    20821 ctcgttctcc tgtgtaatat ggatcggtat cgatatcatg cgaaccgtag aaaatttcac
    20881 cgttcttaac tttcatcata gcaacagtgt cttctatata accaagataa tttaaacttc
    20941 caacagcgcc accaacttca attggttttt ctacatctat tgaaccttta acgacagatt
    21001 tcttaattgc tccatctcta ccgacagcat tattatctcc gctattttgc gaccaataag
    21061 atataccagc agctttagct cgcttacctt taatattagc ttcaacgtat gctttttcga
    21121 catatccttt ccagttttct ccaacaatac ctgttaagaa cttatcccca tctccaacag
    21181 aagttacatt accaataaat gcaacattaa ctaatctacc accactgtca attttatcaa
    21241 tgaaaccaga tacccagttt ctgccgagca cattaccttt gactttaaca ttctcaataa
    21301 ggctaccacc tttgatcaca tttgctacag atgcaatttg atcagcccaa ggcatatcga
    21361 tatttacatt gttaagatta atatttttaa cggtaccacc aacaatattg ttaaataatg
    21421 ggcgcgcagt attgtgaatc gtataatgtt gaccatcaac acttgataat ttacctttaa
    21481 attcacctgt tacatatgat ttacttggag ttggagtatt cgctgcatta agatctgcac
    21541 ctagtttgaa tgtaccagta ggattttttt gcatatctgt aattaactcg ttaaagctat
    21601 agtacacatt atctactttt ggtaattgtt tttcaaagta atgtacatac tcttcgctta
    21661 gtgtatcatc ttctctacgt tgaactaaat caggagcttt agctaccact ttgtacaatg
    21721 tttttccatc aacaacaact tcttcaactg aacttactgc cagtcttgtt gttttgttat
    21781 catgagttgt cactcgtagg taaagtggag caacgtctgt cggtttttca gtaagtaagc
    21841 tcttatctgt ttcaacacca gcatcatcca cactcatcaa gctagtttct ttgatgtttt
    21901 tgatttcaac ttttttaagg tctaactgaa cttctttatc ttctaacatt tcagtttctt
    21961 cgccttcgcc tcgattatag accatggttg tggatagtgt ataaccttga taatatttca
    22021 agttgtctaa agtagcgttt aagttatttt cttctaccgt tacttcttta ataactgttc
    22081 cagtattatc ttttagagct actttgatgg atttgatttc taccccatct ggtttattca
    22141 atgtataact ggctgtcgca ctcttcttca agacatcttt atctgtttta acccattcta
    22201 aggttggttt ttctaaacct tttgtgcctt ttttgataat ctcatcttga ggttgttcaa
    22261 ttactgtttc cttaactatt ggagcttcat ttgttttttc tccacgaatt gttttataag
    22321 tttcagtaat ttgtttctta ccttctacac ctttttgaac tacttgtctt gttccgcgtt
    22381 ttaaagtgtc atcttcttgt tcttttgttt caaaaggaat gacttcttct cttgtttcaa
    22441 ctgttgttcc ttcaactggt tttgttcctt ttttaacgac tttaggaaca gcaggagttt
    22501 ttacttctgt agttgtagaa aggactttgt ctgtttccac accttccact gtttcgtaag
    22561 ttgttttcgt aatttgaact cctttagacc cttgacgttc aacaacttct tcatctacat
    22621 attttgtgtc atccggaact acttctattg tgaaatctaa ttcactttcg gtagacttct
    22681 caactgtacc tgttgttact ttatattctg ggtttacttc ttgtactggt gcttgacctt
    22741 ctttgccttc ttcttgcgta cctttagctg ttttagtctc ctcttttggt tctacagttt
    22801 cttcagcctt ggtatctgga gttgactctt cttgtttcgg tgtttcctct acagccttct
    22861 cttcttcagg agcttctggt tgattttctg gctcgactgg tgcctgttcg tcttttcttg
    22921 gcgcgactgg ttcacctgct tgttcaactt ttgattcctc agctggtttg tctgatggtt
    22981 gactttctgg cttaactgct actttttcct ctggttttga ctcaacttct ccacctactt
    23041 cttcaactgg agctggttct gctgaatctt ctttcccctc ttctacttta ggaagggtgt
    23101 cgtcagtagg ttttacctcc gattttggtt cttcctttgg actttcttct gttttaggtg
    23161 cttcttcttt tggagcttcc tctgtctcta ctacttggtt ttctgtccta gcttgctcct
    23221 gatttgttgt tgattgagga gtctcaactt cgactacagt cacctctcca ggttttgctg
    23281 aggtttcttc taaaacagtg tccaagccaa gcgttttgag gatgtcacct gatagataac
    23341 caacatagcg atagccctcc atttcaacaa caccctctcg actagccagt gctagggtcg
    23401 caactgggtc tacagcccct gcactaggaa gaactaccaa tcccatagtt ccaactagaa
    23461 agacgctagc aattttcttt ctcttgtaga ttaaaagcaa gctcccaaca gtcagcaaac
    23521 caaaagctgt caaaacagat gcttctgtcc ctgtttgagg caactgatct ttttgataca
    23581 ccaaaccata tacaacttca ttcctgtcag gctttcctgt ctgaattaaa tctttagctt
    23641 cttgtgaaat aatctcttta tttacatagt gataggtggc tgcgtccact acagaaggag
    23701 ccatcaaaag gcttccaaga aatacagagc ctacaactcc cttaatctta cgaattgaaa
    23761 aacggtcttt tttaaacact tttatctcct ttattcattc tcaaaacttc ctaatagcat
    23821 cttgcggata gtgcgcacgc gcacctccga ttaattttgg acgactagtc agtgccgtta
    23881 catgggcatg accaatctct ctcaaaatag ggcgaatcgg aacctgaaca tgcttgacat
    23941 gcatgccaat tgcagtgtct ccgatatcca atccagcatg agccttgata aattcaacct
    24001 caactggatc ctgcataaac ttaaaggctg ccaactgccc cgaacctcct gcatgaagag
    24061 taggatggac actgacaatt tccagaccaa actgctctgc cacctgacgt tcaacaacga
    24121 gagcccgatt gacatgctca caaccttgaa ctgctaaatg gatacctcta ctacctagaa
    24181 tacccaagat agtctccact atcagctcac caatctcttg actggattct ttcccaatct
    24241 gaccacctag cacctcacta gaagatagac ctaaaacaaa aagggccccc tgtttcaaat
    24301 tggtcttttc taaaacatct tccactacct gacgtgtttc tctttgaatc tgtgtctcgt
    24361 tcatctctgt tacctctgtt gtcactcttc tatcataccg ttttttcttg tttttagcaa
    24421 gatagacaac ctagaaagtt tgcccaatta cgcataaaac tcccagaatt gactgggagt
    24481 tagctagttt ctattctatt tatatatatt tcaactttcg ttcctttttg gggtctagaa
    24541 tcaatcttca tctggtaatt ggctccaaaa tgaagtttga gccgttgatc gacattttga
    24601 agaccaactc ccccacgttt gagttgactt tgactactat caccagcatc ttggaagcca
    24661 acgccatcat cctcaatacg gatgaccaat cccgaatcct gtttctggac agaaagttta
    24721 atatggccct gaccttcctt ttccttaatg ccatggtaaa gagcattttc tacaaggggt
    24781 tgtaggacca gcttgggtaa gactaaatta tcaaaggcaa cattttcatt aatttcgtat
    24841 tccagcttat ctccatagcg ttgtttctgg ataaagagat actggcggac atgattgatt
    24901 tcgtcagaga gacaaatcaa gtccttgcct tgattgagcg ccaagcggaa ataggttgcc
    24961 aaggacttgg tcacctgcac cactcgctga ctatcatgaa attcagccat ccagatgatg
    25021 gtgtccaaag tgttatagag gaaatgtgga ttaatctggc tcgaaagggc ttgaagttgg
    25081 tactgacggg tcgtttcttc ctggctacga atagctacca tcaactgatc aatctgatcc
    25141 aacatggcat taaattggcg agttacttct ctcagttcat aggcaccaac ttccttggca
    25201 cgaagatttt gagcaccaga agcaatttcc aacatggttt ctctcaaatc cttcaaagga
    25261 gcaatccagc gtttaagact gaaccacact aagcagagac agacaagaag agatgtgaca
    25321 ctggccccaa gcaaggtcca caagagctga ctccgaacct ggtctaactt ttccaatgat
    25381 gacacgccaa gtaccgtcca atcagttcct gcaatcttct cttgactgac gtaggatttg
    25441 tgaccaggag tataaccctg acctgtctcg atgtagggtt tcatagcctc cattttgcta
    25501 gacgaactat aaactgtgtg ttgaggatgg tagacaaatt catggttttc attgataatg
    25561 aaggcaaagc cctgctgccc caactggagt tgattgagat aggcttccag agtttcataa
    25621 gaaatatcca aacgaagcac accaagattg gctccctttg catcaacaag ttcttgagtg
    25681 acagaaatga cccactgact atctgattta cgagctggag tcaaaacagg catagctccc
    25741 tgatgaatag ccttttggta ccaatcctca gccatcatat cagaggaagt tttcatctgc
    25801 acactgtcat ctgtagaaat gacctgacca gatttggtca ccagcacaac agttttcaag
    25861 tccttatctg acttcaagat ggtcaaaaac aaatctcgga ttccctcgac cttgtcttga
    25921 ctgggattct cagcataggc cagaacatcc gtctgctggg tcaaaccagt cgaggtggtt
    25981 tctagttttt tgatataaga ctgaataaag tggctagtct ggctgatggt cgtttggctg
    26041 ttgccctcaa tggtggcctc aatggctgaa gaacttgatt gatagtagaa agttccaacc
    26101 agagctagga gaatgagaaa gaccagaaag atggaaataa ccattctaac taaaagagaa
    26161 gaacgcttca tcggtcttct cccttcttaa actgacgagg tgtcacacct gcaatctgct
    26221 taaaacgttg ggtaaaatag ttcatatctt caaaaccaac cttctctgcg atctcataaa
    26281 tcttcagatc tgtagttaaa agcaagagct tggcttgttt aacacgttct ctcaccagat
    26341 aatcctgaaa aggcaagccc aactctttct taatcaagga actcagatag gtcggactaa
    26401 aacctaagtc actggctaaa gactttaaac taaattggct atcagccaga tgagactgga
    26461 ttttctgggc catgtttcct tcaaacctat tagtcaataa atcttgtaac tgctcttctt
    26521 tctcttcctt gtctagtttt tgtttgattt tccccaacat ttcctcaata tcctgacgag
    26581 aaaagggttt gagcaggtag tcgtccacac ctagtttgac agcagacaag gcataatcaa
    26641 aatcatcgta acctgttaaa aagaccaaat gaacctgagg ataggtttct cgtaccagac
    26701 tggccaactg gatgccattt agatgaggca tgttgatatc ggttaaaatg atatctggca
    26761 cctgcttttg gatcaattcc caagcctgcc ttccattttc agcctgaccg atgatttcca
    26821 tatcgtaggc tgctacattg accagtttag tcaaaccttg tcttaccaga tattcatctt
    26881 ctacgattaa gattgtgtag gtcatgcttc tctcctttgt cacttactag tatcagtata
    26941 gcaaaattct cctctaactg cttaggaaag acctcttata ctcaataaaa atcaaaaagt
    27001 aaactaggaa gatagccaca ggtttctcaa agtatagctt tgaggttgta aataaaactg
    27061 acgaagtcag ctcaaagtat agctttgagg ttgtaaataa aactgacgaa gtcagctcaa
    27121 agtatagctt tgaggttgta aataaaactg acgaagtcag ctcaaagtat agctttgagg
    27181 ttgtagataa aactgacgaa gtcagtaacc ctacatacgg taaggcgacg ctgacgtggt
    27241 ttgaagagat tttcgaagag tattaatcaa cataatctag taaataagcg tagccttttt
    27301 cttccatttg gtctttggga ataaagcgga tagagaggct attgatacag taacgtaagc
    27361 cgcccttgtc ctgtggacca tccgtaaaga catgcccaag gtgagaatct cctactcggc
    27421 tccgcacttc catacgcgtc atattgtagg acttatcttc cttgtaggtg acaacatctg
    27481 gactgatggg ttgggtaaaa ctaggccagc cacaaccaga ctcaaatttg tcttttgatg
    27541 aaaagagagg ttccccagtt gctatatcca catagatacc ggattcaaat ttatcccagt
    27601 aacggtttga gaaagctcgt tctgtttgat tttcctgggt aactgcatac tcctcaggtg
    27661 acagggtctt tttcaattcc tcatcacttg gttttggata tttgctggca tcaatgacag
    27721 gataggccgc ctgattaaca ttgatatggc agtagccatt tggatttttc ttgagatagt
    27781 cttgatggta atcctcagcc accacaaaat tcttcaagtt ttccttttca actgctagag
    27841 gttgatcgta tttcttagcc acctcatcaa agacttggtt aatcacttcc aaatccttgt
    27901 catctgtgta ataaacacca gtacggtact gggtccccac atcatttcct tgtttatttt
    27961 tgctggttgg attgataatg cggaaatagt gaagcatgat ttccttgaga gaaatttgct
    28021 tggcatcata ggtgacatgg acggtttctg catgacctgt ttggttaatc aattcgtact
    28081 tggttgtttc tcctctacca tttgcatagc ctgaaacggc atccgtcacc ccgggaacgc
    28141 gtgagaaata ttcctccact ccccagaaac aacctccagc tagataaatt tcgtgcaagt
    28201 ctgcgtcttt actaatttct gtttttttca ctgcttttcc tccttggcta actgccgcct
    28261 tttcaatttg cgaggcatct gtctgccctg catttcgtat caatagaaca tagaaaccgg
    28321 ttatggctag aaaaaatact cctagcaaca agaagatttt taacttatca ttcataagac
    28381 acctcctagg ctaattcctt caaagtttgc aaaattgcat ctttttccat gaatcctgga
    28441 tgtgttttga ccagcttgcc ttctttgtct ataaaggctt gggttgggta agaacggaca
    28501 ccataagttt ccaaaagttt gcctgatggg tcaactagga ctgggagatt tttataatcc
    28561 aatcccttat accaattctt aaagtccgct tcagattgct ctcccttatg tcctggtgac
    28621 actactgtca agaccacata gtcatcacca gcttctttag caatctcatc cgtatctgga
    28681 agactagcca gacagatgga acaccaagaa gcccagaatt tgagatagac tttcttgccc
    28741 ttgtaatcag ataaacggta ggtcttgcca tctactccca tcaattcaaa atcagccacc
    28801 tctttccctt tagctgcgct tgttttacta gctgtctgct ccgtcttcat ttcatctttc
    28861 gtttggtgtt cactagtcac ggacttgcct gaacaagccg tcaaacaaag gagcgaacct
    28921 gctccaagaa cacatgtttg ccattttttc atattgatat tcctttccat tttattcaaa
    28981 taattgactt aaaattgaag catttccaaa cagaaccaag agtcccatca caataatgag
    29041 aaaaccaccc acttttttga ggattccgag atagggatga agttttcgga aatgtttcaa
    29101 aacataacta gaggtcagag ctagaagcaa gaatggtagc gccaagccca gcgtatacac
    29161 caacatgaga ccagctccct gccaagctcc tgaaccacct gaagccgcca aggccaaaac
    29221 agaccccaga accggcccca cgcaaggcgt ccaagcaaaa ctaaaggtca agcccaataa
    29281 aaatgcctga ctatagccct taccattttg cccctgtcct tgcagttgta gtctcttttc
    29341 cttataaagc cccttaaagt gtagaatctc catttggtgc aaaccaagaa ggataataat
    29401 tgccccagta agatattgga accaagaagc ataaagcaaa tcgcctaaaa aaccagctcc
    29461 atagcccaac aaaataaata taaaggaaat tcctgctata aaggccagag ttcgtaataa
    29521 actagtaact gagattgaaa atttgccgct agaagcctga gcaccatcct tatcatctag
    29581 taacactcct gtatagaccg gtaacaaagg taagatacaa ggagaaaaga aggatagaat
    29641 ccctgccaaa aagacactta gaaaaaagaa aatatgaccc ataaagttcc tcctatcatt
    29701 ttattgatag atttattata ctccttccat tttcgaaaaa acagggacaa tgatagggga
    29761 aaataggaat ttaatcagat gatttagaaa tcttggacaa aaactataca aaaaactgtc
    29821 aaagcacaaa agcgcatagt atcaaggttc tataaagtct tgatactatg cgcttttata
    29881 atggataaat agttagtctt ttttaaagac cggatctttc aaactctgca tactggcatt
    29941 gataaccgcg cctaggataa caattttagc aatcaagata aaccaaaaca tcataacaac
    30001 aagaagaacg gaacctaaaa ttcggacatc caccaaatga tggacatagt aattgagata
    30061 actagagaac agagttagta aacctaaaat cactaagaga acaaaggcac tgcctggtag
    30121 ggtatagcta attttcctgt tagatagatt gggaagaaaa taataaagca tgaccaagat
    30181 agcaaagagg agggcgtaaa tcagaggacc tgccaaccct tgtaaagcct gatagataat
    30241 gccatctttt gtccaataat gagcaagtaa agccaaaatc atctgaccaa ataagatcaa
    30301 aaacaaggca aacgcaaaga ggagctgcaa gccaaaactg actaggagac ttagcatctg
    30361 atgggaaata agtccacgac tcttttcgac gccataagcc ttgttaaaag ctttttgcaa
    30421 gaaattcata gattttgaaa aactccataa cgccgataaa acagaaaaac tcaataaacc
    30481 tgttgaaggt tgcgtcaaga cttctctggc tattttttcc acaccttcat agaggcttgg
    30541 gggcaggacg tctttcataa agcccagaaa ttctcccaca ggaatctgaa aataggggag
    30601 gatattgacc accaccaaaa gcagggggaa aatcgaaatc aaccaatagt aggctactgc
    30661 gacactggtc aactcactat ctgatgcttg ataataatgc aaaaaagctt ttaataaagg
    30721 cttgtctatc agctctttcc accacttttt catgtcacac tccttcactt ataatcttat
    30781 actcaatgaa aatcaaagag caaactagga agctagccac aggctgctca aaacactgtt
    30841 ttgaggttgt agataagact gacgaagtca gtcacataca tacggtaagg cgacgctgac
    30901 gtggtttgaa gagattttca aagagtatta actaatttct tcttaccaat tccaccatat
    30961 catacggcag ggtattggca gcttccttca aggaatagtt ctctaagtta tttacatttt
    31021 gtcgtaattt cttggcatac ttagttgtaa ttaatcgttt ttcttcgtat tcgaaaatca
    31081 acttgcgctc cagataatag cctctcagca tttcatcgat attgttgggt ttgacacgat
    31141 tgataacccg ttcgacaaag gcaccactgc tgataatagc cgtttctcga agacgagact
    31201 cctgcataaa actaatcaaa gagcgtctgt agactccctt caggttttcc aaactttcaa
    31261 taatcatctc tgtattggca agatagagct ctgcaatttg gtcataatca agagcacgga
    31321 gacggctttg ctccttgtcc ttccagctac ggaaggtctt tccaagagta aaaacttcat
    31381 gaaggagaaa acgtaaaatc ctcaaggaaa caagaaaata ataggtcagt cttgaggcaa
    31441 gtttacgatt gattcctcgt tctatatttt tcagataacg ttggtaaact cggtaagcac
    31501 gattgctaat gttcccctct tcataggcct gttccaaacc atcactttca atactaagaa
    31561 tcaagagttt caaagcagcc cagtcttctt gatcatcctg gttttcttgg cttaaaatga
    31621 gattttcaat acgtccatga taattgtcaa tagccgcata gaggggaagt ttatttctgg
    31681 tgtcttccaa ttctttttcc aactctagcg ttacttcatt caaaatggcg atatgcatga
    31741 gataatcctt gctttcttcc tcttcatcag aaagatgagg caagatcaag agacctgtta
    31801 aaaagctgac aagcgtcaca cctgcaacaa ggaaaagcaa aagaggatac tcttgttcta
    31861 gattacttgg tatcaagaga atcgtagcaa tcgacaccgt tcccttaaca cctgaaaagg
    31921 tcaagagaaa catgtccttc atatacttat ttagcttttt cttgaggcgt cgggttctat
    31981 aggcataata gccatagatc ataataaaac gaatgacaaa gaggacaaag gtaagggcga
    32041 tgagagatag caataaaagt agaggattat agattggatt ggtcaagata ggttctgcta
    32101 tcatttccaa ctccatccct aaaatcacaa agacagaacc gttgagcata aaggtcactg
    32161 tatgccagac cgtctcggtc accgtatcca cttgggcttc gaggagcgtg attttcttga
    32221 agcgacttgc ctttaaaatt ccagcaacta cgacggcaat aatccctgaa acatgaactt
    32281 cttctgccag aaagaaggtc actagaggca aacttaattc taataaaagt tcactggcaa
    32341 tatccgttgc gcgcacactt agcaagaagg tatggaggaa gcggttggtc atggctgtta
    32401 aaaatccaat taaaaaaccg cctaggattg aaaagatgag cgaactgcta gcttgcccca
    32461 gagaaaaagc tccagttgtc caagctgtca aagctacctg aaaagccacc aaaccagaag
    32521 catcattcaa gagtccttcg cccttaagaa tattggacac gcgcttagga aagctaaaac
    32581 gctccgaaag agaggcaaag gccaccaagt ccgtaggacc aagggctgcc ccaacagcca
    32641 agcaagctgc caagggaagg ctgaaccaaa gaagatgggc caagccaccc aaactcaggg
    32701 tcgagataaa aatcactgga aatatgagat aaacaatgat tcgccagtgt tttaaaatag
    32761 ccgtaacatc tgcttcttca gcctctcgga aaagcaaggg tccgataacc agggccaaaa
    32821 acaactccgt attgaggtga aagtcggtat tgggtaaaaa gagaccaatc acaattccca
    32881 aaagaatttg caccaaaggg agaggcaaaa agggcaggag cttattggtt gtacttgaga
    32941 caatcaaaac cagtaaaaat aggatgaggt aaatcagtaa ttccacgcac gtcctcctta
    33001 atctttttta caacaggatt caaatatctc cttctgctct ttgatttttt ggtcaatctt
    33061 ggaacagtct ttgtgctcaa tttttctctg gcaccgttcc atttcaagag caactaattt
    33121 tttcttgatt ttaagcattt ttttgctcat atgcgcttgg tctagcacgc ccaccgatcg
    33181 ttcgtggtgg gttgattcaa caaaattctg gcgcatggca tccagctttt cgtgtaggta
    33241 ttgtttatcc atgtctgtat ctctctaatt tttcaatcat cactaaaaac ggcgggttgt
    33301 tgacttggtt taaagttcgg taaatggcag ctgtgtactc ttgttggttc aactggatta
    33361 caaaatccaa gacagcatct ctctcgaggt cgcctccttc atgaccatag taaatcataa
    33421 tagcaattcg tccacctttg acaagtaagc cacatagctt ttctaatgcc tcaatcgttg
    33481 tctgcggtcg ggtgatgaca gacttatcag ctgacggcaa atagcccaaa ttaaaaatcc
    33541 ctgccttagc ttttgtcaca aactggtcca gtgtctcatg gccttgcaag attaactggg
    33601 catttgtcaa gccagcctga tgcaaacgct cttgggtctt ttccaaggct tgcttctgaa
    33661 tatcaaaggc atagacttgc ttggctagct tggctaaaaa aagcgtgtca tgaccatttc
    33721 ccatagtcgc atccactacg acatcctctt ttgtcacgac ctcagccaaa aaatcatgtg
    33781 ccatctcaag tggtcttttc attttcaaac tcctgtttta cagccttgca tccttgaaca
    33841 cttccacgac gtcgcatctc catctcaatg ctgttgagag cttcccattt attgaggctc
    33901 cacataagcc caatcagcat atccctaggt gcatctcctg tgattcgatg gatgacgata
    33961 tgtttgggaa tgatttccag ttggtcacag atgaccctga catattcgtc ctgactcatc
    34021 aattgtaaac gtccctcatg gtaatctcgt tgcatacgag tatttgtcat aagatggagc
    34081 aaatgcagtt taatcccttg aatatcgtta ttcgtgacac aacggcggac attttcaacc
    34141 atcatctcat gggtttcacc aggcaaacca ttaatcaaat gggaaacaat ctcaatcttg
    34201 ggatactttc tcaaacgctt gaccgtttcc acctacaatt cataagaata cgcacggtta
    34261 atcaggtcag aagttgcttc ataagtagtc tacaagccca attcaaccgt cacatgcatg
    34321 cactccgata actcagccaa atattcgatg gtttcgtctg gtaaacagtc tgggcgcatt
    34381 ccaatattga ttcctaccac acctggctca ttgatagcct gttcataacg ctctcgaata
    34441 acttccacct tttcatgggt gttggtaaaa ttttgaaaat aaaccagata cttctgaaca
    34501 tccggccact tacggtgcat aaagtcaatt tccttataaa attgctcacg gataggcgca
    34561 tctggggcta caatagcatc tccagaacct gaaaccgtac aaaaagtaca gcctccatga
    34621 gccacagttc catcacgatt gggacagtca aattccgcat caatagggac tttaaaagtc
    34681 ttttctccaa agagttttcg ataataatca ttcaaggtat tataagattt tataactttc
    34741 attataacaa aaatcaccca caatctcaaa agcctgactt tcctataaat tcctctgttt
    34801 ctcgtttcca tta
//
LOCUS       DAVMBH010000020        33641 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVMBH010000020 DAVMBH010000000
VERSION     DAVMBH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.020"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..399
                     /locus_tag="VYP30_001067"
     CDS             <1..399
                     /locus_tag="VYP30_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1808082.1"
                     /translation="VQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPES
                     PKPTEEPEEESPEESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTG
                     LKNNLLFGTQDNNTIMAEAEKLLALLKESK"
     gene            821..1201
                     /locus_tag="VYP30_001068"
                     /pseudo
     CDS             821..1201
                     /locus_tag="VYP30_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            1659..2372
                     /locus_tag="VYP30_001069"
     CDS             1659..2372
                     /locus_tag="VYP30_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1808083.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2430..2834
                     /locus_tag="VYP30_001070"
     CDS             2430..2834
                     /locus_tag="VYP30_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808084.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQ"
     gene            2841..3032
                     /locus_tag="VYP30_001071"
     CDS             2841..3032
                     /locus_tag="VYP30_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808085.1"
                     /translation="MYFRFFSNFDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEK
                     IIFERGSKMLNDLKSNYKK"
     gene            3170..3823
                     /locus_tag="VYP30_001072"
     CDS             3170..3823
                     /locus_tag="VYP30_001072"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1808086.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3833..4297
                     /locus_tag="VYP30_001073"
     CDS             3833..4297
                     /locus_tag="VYP30_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1808087.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4310..5578
                     /locus_tag="VYP30_001074"
     CDS             4310..5578
                     /locus_tag="VYP30_001074"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1808088.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5592..5852
                     /locus_tag="VYP30_001075"
     CDS             5592..5852
                     /locus_tag="VYP30_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808089.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5863..7224
                     /gene="pdrM"
                     /locus_tag="VYP30_001076"
     CDS             5863..7224
                     /gene="pdrM"
                     /locus_tag="VYP30_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1808090.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAILVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7378..8346
                     /locus_tag="VYP30_001077"
     CDS             7378..8346
                     /locus_tag="VYP30_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1808091.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNVEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8362..9354
                     /locus_tag="VYP30_001078"
     CDS             8362..9354
                     /locus_tag="VYP30_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1808092.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            9572..10615
                     /locus_tag="VYP30_001079"
     CDS             9572..10615
                     /locus_tag="VYP30_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1808093.1"
                     /translation="MVDDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10679..12364
                     /gene="lpdA"
                     /locus_tag="VYP30_001080"
     CDS             10679..12364
                     /gene="lpdA"
                     /locus_tag="VYP30_001080"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1808094.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12428..13417
                     /locus_tag="VYP30_001081"
     CDS             12428..13417
                     /locus_tag="VYP30_001081"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1808095.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEITEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13490..14560)
                     /gene="xerS"
                     /locus_tag="VYP30_001082"
     CDS             complement(13490..14560)
                     /gene="xerS"
                     /locus_tag="VYP30_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1808096.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAKNIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(15054..16604)
                     /locus_tag="VYP30_001083"
     CDS             complement(15054..16604)
                     /locus_tag="VYP30_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1808097.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16620..17399)
                     /locus_tag="VYP30_001084"
     CDS             complement(16620..17399)
                     /locus_tag="VYP30_001084"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1808098.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQSLSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17386..18237)
                     /gene="ylqF"
                     /locus_tag="VYP30_001085"
     CDS             complement(17386..18237)
                     /gene="ylqF"
                     /locus_tag="VYP30_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1808099.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETFRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18404..18607)
                     /locus_tag="VYP30_001086"
     CDS             complement(18404..18607)
                     /locus_tag="VYP30_001086"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1808100.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVRNSFLLPLKSHHLMAFFYIG"
     gene            complement(18659..24550)
                     /gene="iga"
                     /locus_tag="VYP30_001087"
     CDS             complement(18659..24550)
                     /gene="iga"
                     /locus_tag="VYP30_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HEV1808101.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRKETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVN
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEESSNPSDS
                     TTSVGESNRPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDSYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DRDAQIQDSYAEGDINNVKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     SPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPAVKLTELY
                     LEEQFSKTKQNLGGSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     HHGTTDLFSALETYRKVFLPNTSNNDWFKKQTKAFIVEEKSTIAEVKAKQKQAGTKYS
                     IGVYDRITSNTWKYRNMVLPLLTLPERSVFVISTLSSLGFGAYDRYRNSEHKAGKDLN
                     NFVEENASETAKRQRDHYDYWYRILDNEGREKLYRTILLYDAYKFGDDTTSGKATVEA
                     KFDSSNPAMKNFFGPVGNKVVHNHHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPYDATITINSILKHSKSDSLEGSRLQVL
                     DPTERFQNSADLQNYVHNMFDLIYMLEYLEGQSIVKKLNVSQKMEALRKIENQYLTDP
                     ADGNEVYATNVVKELTEEEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAP
                     IFSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEGIAKQNGQTINLYGK
                     KQGLVTDKLVLEKIFSGKYPSWTAFKKAMYQERIAQFDHLTKVIFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24759..25937)
                     /locus_tag="VYP30_001088"
     CDS             complement(24759..25937)
                     /locus_tag="VYP30_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808102.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(26197..29847)
                     /gene="addA"
                     /locus_tag="VYP30_001089"
     CDS             complement(26197..29847)
                     /gene="addA"
                     /locus_tag="VYP30_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1808103.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQVMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWVISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29844..33119)
                     /gene="rexB"
                     /locus_tag="VYP30_001090"
     CDS             complement(29844..33119)
                     /gene="rexB"
                     /locus_tag="VYP30_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1808104.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKISSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLTNLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWNVFLKEGVVTKQLQDLTATMEAIEQERQAEVWKAFCHVL
                     EQFATVFAGSQISLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKIAQNTSLLTDEERQNINQATEEGVQLLIASSENLKKNHYTMLSLVNSA
                     RKQLVLSAPSLFNESESKESAYLQELVHLGFSRKEKRMNHKRLSKEDMGSYHSLLSSL
                     VAYHQQGETSDTEQDLTFVKVLARVMGKKLDQQGLENPALPTSPSSKQLTKDTLQALY
                     PAEQEFYLSTSGLTEFYRNQYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PDEDSFDNRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPVIE
                     TIKEEANFGGKEQAFIQLDNGRSVFVRGKVDRIDRLKADGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33319..33474)
                     /locus_tag="VYP30_001091"
                     /pseudo
     CDS             complement(33319..33474)
                     /locus_tag="VYP30_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9674 a         6579 c         6898 g        10490 t
ORIGIN      
        1 gttcaaagaa acaaaaatgg tcaagctgat accaatcaaa cggaaaaacc aaacgaggag
       61 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
      121 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga agaatcacca
      181 gaggaatcag aagaacctca ggtcgagact gaaaaggtta aagaaaaact gagagaggct
      241 gaagatttac ttggaaaaat ccagaatcca attatcaagt ccaatgccaa agagactctc
      301 acaggattaa aaaataattt actatttggc acccaggaca acaatactat tatggcagaa
      361 gctgaaaaac tattggcttt attaaaggag agtaagtaaa ggtagcagca ttttctaact
      421 cctaaaaaca ggataggaga acgggaaaac gaaaaatgag agcagaatgt gagttctagt
      481 tctcattttt ttcatgaaaa tgtgcaaaat atagtagatt gaaactagaa tagtatacct
      541 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gttcttattt cattttacta
      601 tatcttaaca gatagtgtaa ataaagataa actatttact ggctaattga tcagttaaac
      661 actagttaag gagtaatgat gaaaaaaaga acaatactat tattgatggc cagtctgtta
      721 gctcttgtct taggagcatg tggtttcttg gacatattga tcctggatca ttctcatcag
      781 gattactctt tactgctatt ttagaaactg gggtggtttg atggaaagta ttggtattgg
      841 tcttgttatc gtttcacatt ccaaacacat tgcagaaggt gttgttgaac tgattagtaa
      901 agtagctaaa gatgttccga ttacttatgt aggaggaacc gagggcggag gaattggaac
      961 gagttttgat taagtagata gggttgtttc cgaaaataca gcagatactt tacttgcctt
     1021 ttttgaccta ggttctgcta aaatgaactt aaaaatggtg actgatttca gtgataaaag
     1081 tatcatcatc aacagggttc caattgtaga aggtgcctat aatgcagctg ctcttcttca
     1141 ggctggtgca gaactgtcag ttattcaaac acagttagcg gagcttgaaa tcaataaata
     1201 aggaatttta ctataactct ttttataggt aagctattga ttatctcaac tataaaatgt
     1261 taagtaaatg atttcaaaat cagaaaggga ttgctttatg cagttccttt ttattttaac
     1321 aggagtgaaa ctatagtgtt tctaaattgt gaatcaatca aaactgattg tgatggggct
     1381 attctagctt tagaaacctt caaaaattaa aatttaaggc aatcaattac ttggaagagt
     1441 atgaaagcat ttagtttata ggaattctag gtctagaatt acacatatat ttatgaatac
     1501 ggggtgctcg atagttagta ttgttctatt ctgaaagatt tgagctgtca gttgtataga
     1561 aagtgttcga atttttttaa gtgattaaat tagttaattg tatgaggtgc tttatgatat
     1621 aatgttctta atgaattttc agaaaggaaa acctcaaatt gttctacaaa tttctactct
     1681 tcgacctcga ccacactctt cttgattttg atgctgctga ggatgtggct ttgacccaac
     1741 ttctaaaaga agaaggagtt gcggatattc aggcttataa agattattac gttcctatga
     1801 acaaggctct ctggaaagac ttggagctga agaaaatcag taaacaagag ctggttaaca
     1861 cgcgcttttc tcgtttattt tctcattttg gacaggaaaa agacggtagt tttcttgccc
     1921 agcgttacca attttatctc gctcagcagg gacaaacact atcgggcgct catgatctct
     1981 tggacagcct cattgagcgt gattatgact tgtatgctgc gacaaatggc attactgcca
     2041 ttcagacagg acgtttggct caatctggtc tagcacctta tttcaatcaa gtctttatct
     2101 cagaacagtt gcaaactcaa aagccggatg ctctttttta tgaaaagatt ggccagcaaa
     2161 ttgctggatt tagtaaagaa aagacgctga tgattggaga ttctctaacc gccgacattc
     2221 aaggtggcaa taatgcgggg attgacacta tctggtataa tcctcatcac ctcgaaaatc
     2281 acacacaagc ccagccgact tacgaagtct attcttacca agacttgctg gattgtttag
     2341 ataaaaatat tcttgaaaag atcacatttt aaaggagacg agctaatgac tacaaaaaag
     2401 ctaatattac tattgaagag tacattgaaa tgtctgaagt tgattttaat gaagctgtta
     2461 attatgaatt tacatctgac acttgtcaat tagcaaatag tatttatcaa tctcttttta
     2521 agttttttga taagaaaaat ttctctggcg atttaatttt tacttggaaa tctccatcat
     2581 tagtcaaaga aggggattat attgggagaa gggattcaca agtagataat cttagagtaa
     2641 taggaaatat atttccgaat tatcttacta atcgaaaata tagcctcaat atgaatcgta
     2701 atggctgtat gggagatttt cctcatgact tttttgatat atacctagat catgtagcaa
     2761 aatatgccta cgaacaaaaa gttaataata ttaaagagta ttatccttta aaaagagcga
     2821 ttttacacca atagaatgca ttgtattttc gatttttttc taattttgac gactttttag
     2881 aaaaaaatta tttaaagact atatggcaag tttctaaaga aactcctttt tctgaaatgg
     2941 attttaatat gtttaaaaat atttcagaaa agataatctt cgaaagaggt agtaaaatgc
     3001 ttaatgattt aaaaagtaat tataaaaaat agccagtctt tataaactgt attcacgtat
     3061 tcaaatcgta tatatagtcg atttattaaa tctttagata aactgtaaaa agtggtttcc
     3121 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcggcta tggaacactc
     3181 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
     3241 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
     3301 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
     3361 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
     3421 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
     3481 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
     3541 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
     3601 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
     3661 taagaagaag gcattagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag
     3721 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaagg ccaatgcatt
     3781 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
     3841 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
     3901 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
     3961 agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa
     4021 gccagttcta aaaggtgtca tcacttttcc tgaatttaca ccagatttag actggtacac
     4081 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     4141 agaatgggtt ccctatgatg aggttttgag caagccgact tgggaaggtg accacacctt
     4201 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     4261 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     4321 caaaaatggt cgtgtaatgg atcccaagtc tggtttggat caagtttgtg atgtcttagt
     4381 tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag cagaaacgat
     4441 tgatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc atttccgtga
     4501 acctggtcaa acacataaag aagacattca tactggtgcc ctggcagccg ctgcaggtgg
     4561 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     4621 gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     4681 tactaaaaac tttaatggta aaaacttgac tgactttaag gcgctcttag aagctggtgc
     4741 ggctggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     4801 ggaggaagcc aaaaaattca atacctttat cagccttcat gaggaagatc caggtttgaa
     4861 cggtgttctt ggctttaatg aaaatattgc tagagaacat ttccatatct gcggtgctac
     4921 tggagtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     4981 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     5041 ggggttaggt gcagaagtca cagcagaagt agcaccacag catttctcta agacagaagc
     5101 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     5161 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     5221 cgcgcctcat catgtagatg aaaaaaatgt tgaagatatt accaaagcgc catctggtat
     5281 gactggctta gaaacatccc tgtctctcgg cttgacctat ttggtagaag ctggtgagtt
     5341 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttaa
     5401 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     5461 ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     5521 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     5581 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     5641 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     5701 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     5761 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     5821 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     5881 ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt
     5941 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     6001 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     6061 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa
     6121 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     6181 gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga agcagcagta
     6241 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     6301 tttagcgtca ttcgttcctt actggattcg ctgggcttga ccaaactgtc catgtacctc
     6361 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     6421 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     6481 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     6541 gagaaacgaa ttccacttaa tatggataaa attaaggaag gagttcgttt aggtctgcct
     6601 attgggggaa ctgtcttcgc ggaagtggct atcttttcag tggttggctt gattatggct
     6661 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     6721 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     6781 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgccctcatt
     6841 tttgcggcct tcaccttaac cttcctttac atttttaggg ggaatgtggc cagtctttat
     6901 ggtaacgacc caaaatttat tgatttgaca gcgcgttttt taacttatag tcttttcttc
     6961 cagttagcag atacctttgc ggcaccgctt cagggaattt tgcgggggta taaggataca
     7021 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatcct tgtggctacg
     7081 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     7141 ttgattgtga gtggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     7201 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tattcttgat aagaaaatcc
     7261 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     7321 gtatttgcca aaaacggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     7381 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     7441 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     7501 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     7561 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cctcaacgga
     7621 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     7681 catatcgccg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     7741 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc
     7801 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     7861 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     7921 gatatcaaga aaatgaccaa tgtagaacat atccatcaac gtagcgccgc ttatggaatt
     7981 cctggaatgt tcatcgaaga cggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     8041 gctgtagacc atgttcgcag tggcaatggt ccagtcttga ttgaaagtgt aacttatcgc
     8101 tggcttggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     8161 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     8221 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     8281 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     8341 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     8401 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagacgtc
     8461 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa
     8521 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagctgcagc aggagcagcc
     8581 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     8641 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     8701 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     8761 tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct
     8821 gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt
     8881 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     8941 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt tacttatgga
     9001 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag cagaagaagg aatttcagtt
     9061 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     9121 aagaagactg gtaaggttat tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     9181 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaatacgc
     9241 cgttgtgcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     9301 ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga ctagagttac
     9361 ataatataag ttatgtaaat aaaataaagc tgacgagaaa ctttgtatct tttaggtgca
     9421 gagctcttcg tcattaatat cttagattag agcacgggct aaaagctcgg aaaaaagata
     9481 aatctccttg gcttcatcga agccatcgtc gatttcctat ttttcagtcg cttttgacgc
     9541 cctttgtatc ataaatagaa ttggagaggt catggttgat gacaagctaa gagcgactcc
     9601 tgcagctaga aagttagcgg atgatttagg gataaacctc tacgacgttt ctggctcagg
     9661 tgcaaacggt cgtgtccaca aagaagacgt ggaaacttat aaagacacaa acgtggttcg
     9721 catttcgcca cttgcaaaac gaattgccct cgaacataac attgcttggc aggaaatcca
     9781 aggaaccggt catcgtggta aaatcatgaa gaaggatgtt ttggccctgc ttcctgaaaa
     9841 tatcgaaaac gatagcatca aatctcctgc tcagattgaa aaagtggaag aagtccctga
     9901 taacgtaaca ccatatggtg aaatcgagcg tattccaatg acaccaatgc gtaaggttat
     9961 tgcccaacgc atggttgaat cttacttgac tgcgccaacc ttcaccctca actatgaagt
    10021 tgatatgact gaaatgttgg ctcttcgtaa gaaggttctt gagccaatca tggaagcaac
    10081 tgggaagaag actactgtaa cagaccttct ttcgcttgca gttgttaaga ctcttatgaa
    10141 acacccatac atcaatgctt cattgacaga agatggcaag actattatca ctcacaacta
    10201 tgtcaatctt gccatggcag ttgggatgga taatggattg atgacacctg ttgtttacaa
    10261 tgctgagaag atgagtcttt cagaactggt tgtagccttt aaggatgtta ttggtcgtac
    10321 cttggatggt aaattggctc caagtgagtt acaaaattca acattcacaa tcagtaattt
    10381 gggaatgttt ggtgttcagt cctttggccc gattattaac caacccaact cagctatcct
    10441 tggtgtcagt tcgacaatcg agaagccagt tgtcgtcaat ggtgaaattg tgattcgccc
    10501 aatcatgagt ttaggattaa ccattgacca ccgtgtcgta gatggtatgg ctggtgctaa
    10561 gtttatgaag gacttgaaag agttgattga aaccccaatc tcaatgttga tttaagagca
    10621 agagtattca tttttaagat atagataaag gaaggaagac atggccttag aagtaattat
    10681 gccaaaagcc ggcgtggata tgacagaagg acaaatcgtc caatggaata aaaaagtcgg
    10741 agaatttgta aaagaaggag aaatcctttt ggaaatcatg actgataaag tcagcatgga
    10801 attggaagcc gaagaagatg ggtacttgat tgccattctc aaaggagatg gtgaaactgt
    10861 ccctgtaacg gaagttatcg gttaccttgg tgaagaaagg gaaaacatcc caacagctgg
    10921 agcagcatcg ccagaagcta gccctgtacc tgtagcaagt acctcaaacg atgatggtaa
    10981 gagcgatgat gcttttgaca tcgttgtgat tggtggaggt cctgctggtt atgttgcagc
    11041 cattaaagct gcccaactcg gcggtaaggt tgcccttgtt gagaaatctg aacttggtgg
    11101 aacctgctta aaccgtggat gtattccaac caagacctac cttcatagcg ctgaaattat
    11161 tgaaaatatc ggtcatgctg caaatcgtgg tatcgtgatt gaaaatccta acttcactgt
    11221 tgatatggaa aaacttttag aaactaaatc taaagttgtt aatactcttg ttggtggtgt
    11281 tgcaggactt cttcgtagct acggagttgc tgttcataaa ggaattggta caatcactaa
    11341 agacaagaac gtcttggtaa atggttctga attgcttgaa accaagaaaa tcattcttgc
    11401 tggtggttca aaagtcagca agatcaacgt ccctggtatg gaatctccac ttgtcatgac
    11461 tagtgatgac attcttgaaa tgaacgaagt gccagaaagc cttgttatca tcggtggtgg
    11521 agttgtcggt atcgaactcg gtcaggcctt catgacattt ggttcaaaag tgactgttat
    11581 cgaaatgatg gaccgtatag ttccagctat ggatgtggaa gtttctaaga accttcgctt
    11641 gatccttgag cgtaaaggaa tgaccatctt gactggtact aaactgcaag aaatcattga
    11701 ggaaaatggt caacttcgta tcaaggttga aggaaaagac gatatcatcg caagcaaagc
    11761 tcttctttca attggtcgta tgccagacct tgaaggtatt ggagaggttg agtttgaatt
    11821 ggatcgtggt tgtatcaagg tcaacgaata catggaaact tcagttccag gcatttatgc
    11881 accaggtgac atcaacggta ctaagatgtt ggctcacgca gctttccgca tgggtgaagt
    11941 ttccgctgaa aatgccctta aaggaaatca tgcagttgcc aaattgaatt tgactcctgc
    12001 agccatctac actcttcctg aagtagcagc agtaggtttg acagaagaac aagcccgtga
    12061 gaaatacgat gttgccatcg gtaagtttaa ctttgctgct aacggtcgtg ctattgcatc
    12121 tgacgcagct caaggtttcg taaaagttat cgctgataag aaatacggag aaatccttgg
    12181 tgtacacatt attggtcctg cagccgcaga attaataaac gaagcatcaa gcatcatcga
    12241 aatggaaatc actgttgagg aaatgctgaa gaccatccac gggcacccaa cttactctga
    12301 agtgatgtac gaagcgtttg cagatgttct aggaatggcc atccattcac ctaagaaaaa
    12361 ataaaacgaa gatagattag actggaaggt tatttccagt ttctatcata taaagtaaag
    12421 ggatatcatg aaatacatta tcaatcattc aaatgacact gcttttaata ttgccttgga
    12481 agaatacgcc tttaaacacc ttttggatga ggatcaaatc ttcctacttt ggattaacaa
    12541 gccatctatc attgttggtc gtcaccagaa cactatcgaa gaaatcaacc gtgattatgt
    12601 tcgcgaaaat ggtattgagg tagttcgccg tattagtggt ggtggagctg tttaccacga
    12661 tttaaataac ctcaactaca cgatcatctc caaagaagat gaaaataagg catttgactt
    12721 caagagcttc tcaactccgg ttatcaatac cctggctcaa cttggggtta aagctgagtt
    12781 cacaggtcgt aatgaccttg agattgatgg taagaagttc tgtggcaatg cccaagccta
    12841 tatcaacggc cgtatcatgc accacggttg cttgctcttt gacgttgatt tgtcagtcct
    12901 cgcaaatgcc cttaaggttt caaaagataa atttgaatca aaaggtgtga aatccgtccg
    12961 tgcccgtgta accaatatta tcaatgaatt accaaaaaaa atcacagtcg aaaaattccg
    13021 tgatttactc ctggaataca tgaaaaaaga gtacccagag attactgaat acgtcttttc
    13081 agaagaagaa ttggccgaaa tcaatcacat caaggatact aagtttggaa cttgggactg
    13141 gaactatggt aaatcacctg aatttaacgt ccgtcgtgga accaaattca ctagtggtaa
    13201 ggttgaagtc tttgctaacg ttactgaatc aaaaatccaa gacatcaaga tttatggtga
    13261 cttctttggt attgaagacg ttgctgcagt agaagatgtc cttcgtgggg tgaaatacga
    13321 acgcgaagat gttcttaagg cgctaaaaac cattgatatc acacgctact tcgctggtat
    13381 tagccgtgaa gaaatcgctg aagcggtagt tggataaatc aaaaagaagt tggccaacta
    13441 accaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat
    13501 ccagagcatt cttttgttca tcactaacaa tatgggtata gaggtcagtg acttgtgtgc
    13561 tagcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag
    13621 ttgctagtgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    13681 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    13741 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    13801 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt
    13861 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    13921 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    13981 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    14041 tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg atatttttag
    14101 ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat
    14161 agaaataagg ttccccctga tcgttttcaa cctcctcggt tagatacttg taaagactag
    14221 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    14281 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    14341 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    14401 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    14461 tgtagggcac agccagctta gattggtagt attccagaac ataccagggc atgagttgtt
    14521 ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc cataagtaag
    14581 tatactagta gtatagcata gacttgtata tttttcaaga aaattatagt ttttcagaaa
    14641 gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata
    14701 aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacatag ctagaaattg
    14761 atttgattgt cctgattgtt ttatcctatt tctatttcat ttcactatat aattgctatt
    14821 gttttctttt tcatgatttt aatcttactg tacagatttg atacagtaaa ctcctttcta
    14881 gctttatgct ttatcatttc taacttaatt atagtcttat ttttaataaa gttcaattat
    14941 ttatatgtaa aattcctcat cagtaaaaaa taaccgatct catttctgag aatcggtttt
    15001 ctaaataaat caagctgagc atttacataa cataaattat gtaaatgatt gtactacaac
    15061 aacaaatctt tgacttttcc aatttcactt tttggaataa ccaggtgaat catatcaccc
    15121 agatacattc tggttgagcc gttaactgtt tggctcttgc cattatggac ttgagttgtg
    15181 atgaggacgt tgtgtggtaa gttgagttca tgaacttgtt tcccagcaat tttatcagaa
    15241 actggtattt cgataagtgt aacttctcct tcgctagata cttcttctgg aagcattttt
    15301 tccagcatgg cttcatagac tggcgtacct ttgagcaaat ccatgataat ataagaaaca
    15361 agagtgacaa gaccaagtgg catgaggttg cgaatatctc ctaccatctc agttacgagg
    15421 atcatagcgg ttaagggagc ttttgatatg gctccaaaat agccactcat tcctagaatg
    15481 acaaatatag ggaattgctc ttgactgaca agtccaagat tgacacagat agcaccaatt
    15541 aaggcaccaa gcaaagaacc aagagctaaa atggggagga aaattcctcc tggcagtcca
    15601 cttccatagc taatcatact ccaaataaag cggatcaaaa agtaagctaa taaaacttgg
    15661 aaactaaaat tttgttcagt taaagaaagg acaagctgat ttccgccacc aatgatttga
    15721 ggtaagaaga ttccgactgg tatgataagg ataaaagcca agatgggata ataagctcta
    15781 tccaaatgga ttttttgacc aatcaagtca taaactcttc caacgtttaa tacagctttc
    15841 tcatagagaa agcctgaaaa tccaaggaaa attcccatga cgagatatat ccaatactga
    15901 tctagggtca tgggaggaat gttatctggc atatccaata ctggtgtcaa accgaacatg
    15961 agtagagaca caaagtttgc tacgatgctg gctgctagag ttgagaccca gaaaaagcgc
    16021 gaaaaatggt gatagacttc ttctacaaca aagagaagtg ctgcaatagg agcattaaag
    16081 gctgcggcta aacctgctgc agctccactg gcaatcaagg aacgttcctc tactggactg
    16141 gatttgagcc acttggcaat tcctttacca ccaactgctc caagttgaat actgggtccc
    16201 tctcgaccca gcatgagtcc actggcaata gcaagaatac ctagtacata ttttttccaa
    16261 agaatgcccc accagttgag ggacatgagg cctttcagtt cggcttcgac ttgaggaatt
    16321 cctgagcctt taatatcttt ttctgaccgt gttagtttgg cactgagcca acagatgagt
    16381 atataaaaca aaaccagtac aaaaagattg cgcactaagt acccttgatc ttgataaact
    16441 ccttgtatca ggtggaagcc cttttcaatt aagaaacgaa aggatccgac gataattcca
    16501 acgatgaggc cgacaatgat tcctcgacca acttgggata gtatagtgct ggatgcaaag
    16561 gcgaattctt tcttagaacg gactatttcc gactgttcct ccatggtatt tcctttcaat
    16621 taactttctt ttttacctaa aaccagtgat ttaacgggtt caaagctggt tcggtgaatt
    16681 ggggtaactc ctagttttgt gaggccttcc agatgtttag ctgtgccata tcctgcatta
    16741 gtagcgaaat catagccagg gaactgctga tcgtattcct tcatcaattc atcacgtgtt
    16801 accttggcta ctatagatgc tgctgcgata gagagggagt tggcatctcc tttgataatg
    16861 gaggtttgtg aaatgggcaa gtccagtttc atggcatcaa tcaaaaggtg ctctggttga
    16921 gggctgagct gggagattgc ttcttgcatg gctagtttgg ttgcttcata gatgttgact
    16981 tggtcgatga cctgattatc tatgatacca attccaatcg acaaggattg gtcttgaacg
    17041 gcttggaaaa tctccagatg tttcttttta ggaattttct tgctgtcgtt gagaccttta
    17101 atcttacaat ttttaggtaa aatgacggcc gcagcgacta caggaccagc aagaggacca
    17161 cgaccaacct catcaatacc tacaattaag gtcaatcctt gcttataaag ttctttttca
    17221 taagaaagca tggattccaa gcgcaaattt tcatctaatt cagcttgaat ggctctttta
    17281 cgcttgctga tttccttttg aactcctgag cgattatcct tttcaagctc taaaaaaata
    17341 gggctttcta actccttgac tgtcacaagg agttctttga tttctttaat cgttgccatc
    17401 gaggtcttcc aatgtatcta aggtatagtt accgagtttg ccatcacgga cttccttcac
    17461 gaagagactg taaaaacggt catagtcatc acggaaaccg agggcgcggg tcatatccat
    17521 aataatcaca ggcgcttctt cttcaatttt catttgtttg aagcgttcag ccagcttttc
    17581 tggataatgt tctttgaaat aattgatacc aaaaatggta acctcatcca taggaagcaa
    17641 ctgatccttg atagctccag tcaatgccaa cttaagtgca acagtttcat cctcaaactt
    17701 aggccagaga atccccggtg tatccaagat ttccaggtct ttattggttt taagccattg
    17761 ttgacctttt gtgacccctg gcttgtttcc aacaacagca atctttttac cagccaaacg
    17821 gttcatcaga gttgatttac cagcgtttgg aatcccgata atcatagtac gaaaggtttc
    17881 aatctgaatc ccacgttctt tctggcgagc aatcttatca gccatgagct tcttggccgc
    17941 atctgttaca acttttacag tcacttgctc tttggagttg atagctagcg tctggattcc
    18001 ttgtgattca aaatactgac gccattcctt ggtcattgct ggatcagcca agtcggcctt
    18061 gtttaaaatc aagagttttg gtttatcacc aacaatcttg gtcaacatag gattttgact
    18121 agatagaggc aagcgtgcat ctactaaaat cgtcacaaaa tcaacaaatt ttaaattctc
    18181 ctgcacctgt cgacgagctt tagacatgtg accaggaaac cattgaatag tagccattga
    18241 gttttttcct ttcgtagctc tgaagctgtt aatctagaac taagagatct caatctaaaa
    18301 atgaatgatg tccaaacagt tcttgtttta tgacataaaa atctacttta tattatatca
    18361 tgccttcttt attttgtccg atgatagcct tttaccctat cttttaccct atatagaaaa
    18421 aagccatcaa atgatgactt ttcagaggga gcaaaaaact gttccgaacc aaaagaacta
    18481 aactaccaac agctaatagg cctaaagctg taagcgcaga agttgatgaa cctgttgcag
    18541 gaagagtttc ctgttgataa ataagagcat aacttacttc attatcagta ggaattcctg
    18601 cttgaatctt ggtttgttct tcatcacctt tttaaacttt atttcctaat agtaaacact
    18661 attttttatt ctcaaaaatt gaacttctaa aatcatttgt ttggtcaaga taggctttaa
    18721 agattgctct cttcaactta tgaacggcac tgtcgatttc tggattataa ttactccaac
    18781 gtggaccttc agcatccttg agaacagctt ggtccatgag ggcttgcaat tcatccacat
    18841 tattgatagt ctttgtgcca tagcttggcc atggttttgt cggatcttta aaaataactt
    18901 tagtcaaatg atcaaactga gcaatacgct cttgatacat agctttttta aaagctgtcc
    18961 aagatggata cttgccagag aatatctttt ccaaaacaag cttatctgtc actaatcctt
    19021 gctttttacc gtaaaggttg attgtctgac cattttgttt agcaattcct tcatattggt
    19081 tggaaatata tggtaccata ccatctttaa atcctttagc agctaagagt tcataagcta
    19141 tccttcgtcc cataagatct ccaggagtac ctttctcact gctcaatgct gaaaagattg
    19201 gtgcaaagag ttttatagta aagtagccat ttctctcata tgtaccagcc ttatactcac
    19261 gagctgaaag aatattattg tcaatcaaac tatcaaaact attcaggttt cgggcctctt
    19321 cttctgtcaa ttctttgact acgttagtag cgtaaacctc atttccatca gcaggatctg
    19381 ttagatattg attctcgatt tttctgagag cttccatttt ctgagaaaca ttcagtttct
    19441 taacaatcga ttgcccttct agatattcca acatatagat gaggtcaaac atgttgtgaa
    19501 catagttttg aagatctgct gagttttgga atctttctgt cggatccaag acttgcagac
    19561 gcgatccttc taagctatct gattttgaat gtttcaagat agagttaatg gtaatggtcg
    19621 catcatatgg atggtctggc gcttgtaata aacctttagc aaagaactca ggaccaagac
    19681 cacttcttcg accatagccg ccaaggtaaa tatcttgatc cgaatcatgg gtcatctcat
    19741 gggtataggt aatggctcca tccttgtcga gcatgcggta agacatatag tagacaccat
    19801 ctcctgttgc gtaggcaccg tgatgattat gaacaacctt attaccaact ggaccaaaga
    19861 aattcttcat ggctggattg gagctatcaa acttagcctc cactgtagct tttccagatg
    19921 ttgtgtcatc accaaactta taggcatcat aaaggagaat cgtacgatat agtttttcac
    19981 gtccctcatt atctaaaatg cgataccaat aatcgtagtg atctcgctga cgtttggcag
    20041 tttcactcgc attttcttca acgaaattat tgaggtcctt gcctgcttta tgttcactat
    20101 tacggtagcg atcgtaagca ccaaatccta gactagacaa ggttgagatg acaaatacag
    20161 atctttctgg caaggtaagg agaggcaaga ccatattccg gtacttccaa gtattactag
    20221 taattcggtc ataaacaccg atagagtact tagttcctgc ttgcttttgc ttggctttga
    20281 cctctgcaat agtggatttt tcttcgacaa tgaaagcttt ggtctgtttt ttaaaccagt
    20341 cattgttgct agtgtttggt aaaaagactt ttcggtaagt ttcaagtgcg ctaaacaaat
    20401 ctgtcgttcc atgatggctg gctagactga taccataagt atcgacattg ttcttggcaa
    20461 gaagattgtt aaagccagat ttacctaact caatcagagt atctagtggg gaagtatttc
    20521 ctttaccaaa gaagtctgga tgatacataa ctaggtcttt gacattcact tgaccatagt
    20581 taaagttata ccaacgttct aaataagtta aaccgagtag caaggcttcc ttattattct
    20641 tgattttatc tacaagatag cctctggtga ctgagttatc gctagctaga ccggcatctg
    20701 ctgacaaaag ttttttcaag ctgcctccca gattttgttt tgttttggag aactgctctt
    20761 ctaaatagag ctcggttaac ttaactgctg gagaaatacc aagtgtcttt ctgatagcat
    20821 ctgactggta atcaagcttc tgcaactcag gcaagacttc cttaacaata gagtctcgat
    20881 catataagaa ttggttagga gtgtagagaa gtcccgtatt acctagatta tattctgcta
    20941 gattggcaaa atcagtctgg tacttgagat caaatttctc agatgaatgg tcattatagt
    21001 gaagtaagag tttgtttgca gtctgtttgt tggaaacaat atctgtgatt acttggtcat
    21061 ccttcatcat aactgcagat aagagttctt tttggtataa gagactgttc tccttaacca
    21121 ggtttccgta tttcacgatg gttgacttat tataaaaagg taacaatttt tcaatgttct
    21181 tataaaccaa agcacggtta gcttgataat gggctatctt agaaaaatca ctgtctttct
    21241 tgccacttgt tgagaggggt tccaccgttg gtagagtgag aggacttatt tctgcttttt
    21301 tgcttacaat ttgagaagca tctagcattg ttcctctttc ttcaaaggat tccttgctga
    21361 cgacctcatc cttctctaaa gtgacattga aaactctatt agccttacta ctaaatgtat
    21421 tagctacctt cattcctgta tagtggtatc cagtgatggc atttccgttt gttacattaa
    21481 catcgctgag aacattggtc aaacttccag catgcctaac atcaccagaa gttcgatccc
    21541 acaaattgcc tgccactcca gcgactctac caaagtgctt gacattgttg atatcacctt
    21601 cagcatagct atcttggatc tgtgcatctc ggtctactag acctgcaaga ccaccgacag
    21661 tctgatctga cctattggtg tttgacgaaa tggttactgt cgctttggat ttagcaatag
    21721 acgcattttt tcctgttaaa tgaccgacca gaccgccaat attgtaggaa tcagtcgttt
    21781 cataggtatt gacaattctt cccttgaaac tgctctctgc gatgcttgat tggtctgcct
    21841 tagccaacaa accaccgaca ccacgttctc cagccagaac accatcaaca tgaacttgtt
    21901 taatctttgt gccattcgta gcttcatttg ccagtgaacc aatatcattt ttccctgaaa
    21961 tagcaacatt ttttagactc agtttttcta ctgtagcacc actcaagttt tcaaaaagag
    22021 gctttttcaa gttgtaaata gcataatgct taccatcttt ttcaccaatc aactgaccag
    22081 taaaggttcc cttgatatag gatttatcat cagtactaag ctccacttcg ttagcattca
    22141 ggctggccgc taaatgatag gttccagagg gattttggtt tatagctttg accaggttgc
    22201 taaaggaagt aaagtttgta ttttcctctt tagccttctt atcgaggtag aaggtgaaat
    22261 tgtcgacata tttattttct agttcttgct ggagtttctc agctttggct gtgattttat
    22321 aaactgactg cccatttctt ttctcttcag ttattgaagc tactggtata tagacatctt
    22381 taaatgctga agattttacc ttgacaaagt aagtatccgt attctctgga attccatcca
    22441 atgaaacatg ttgtctgtag gttccattcg tctgactata caactcaata tcagaaacat
    22501 ttcttaattc gagttttttc tctggttctg tttgtccatt ctctgatgtt gtattacctg
    22561 aattttctgg ttttgttgca gttccgtttt tttctggttg atttgattct tcaactggtg
    22621 gttttgaatc actaggttta ttggatactt ctccagtatt ttcgttagct attttcccag
    22681 agtttgtttg tgtttcttct gcaggttgaa ctggtttttc tgtttcttga tttgaggtac
    22741 cttctactgt gccttcattt ggatttactg gaacttcttc tacagttttt tctgaatttt
    22801 catttttaga gtcattatgt tctggtctat ttgattctcc aactgaggtt gtcgaatcac
    22861 taggattact ggactcttcc ccagtatttt cgctagatgt atctggtgat actttctctg
    22921 aattcgttgt tgattcttct gcaggttgaa ctggattttc tgcttcttga attgaggttc
    22981 cttctgtagt accttcattt ggatttactg gtgtttcttc tgttggattt actggaactt
    23041 cttcagtttt ttctggacct tgttctttgg tcttctcaac cggagtttca ggttttactt
    23101 gctcaatatt acccttatat tctggaagcg gtgctacctg ttcaggttca cctttatcac
    23161 ttaccacagt atctggcgac tctggttgaa cctcagtctc acctttgtcg gttataactg
    23221 ctttggacaa cgctggttga acttctggta cgcctttgtc acttactaca gcttcgggca
    23281 actcaggctg aattgcgggt tcaacaatag ctccagactg tacgtcctta tgttctacac
    23341 cagtctcagg ttgttccttt ataacttgag tttttttagt acctttttcg actattcttg
    23401 gaataggcgc agtcgttgaa gttgaaacaa tttctcgcga aacttcttcc ttgtttacag
    23461 agaatattct gacgatttca actttcttac ctaatttacc ttcttgtttt actcttacaa
    23521 ttccttcaac taaatcagga ttttcttgaa tttcttcttg aaaatctatt tttatctcta
    23581 tagtttcctt acgatataag agttcaggtt tgttcaattg acctgataaa acttcatcct
    23641 gtggatttaa tgtatttacc ccagtctttt cttttggaga aatcttctcc tctttcttcg
    23701 tttctagatt cttatgttcg gctaattgtt cttgagaatc tgaagattgt ttctcttctt
    23761 ttcttggatt gattaattca gtagagaaag gtttttcaac tacttgaact tctgtcggct
    23821 tagttgaaga aacaggtgtt tgttcctgaa tagcttgtac tgttgatgga tggtctacaa
    23881 aatttggtgt aacattataa tccacctttt gttgttttgt aggagtggct gctgattttt
    23941 cttgattact tacttcaaaa tcagaagtcg tttttccctc tttgatatat ccaatataag
    24001 tgtaacctga aatctcttta ggaagaggta atttttctcc agaggtcaat tcatagtccg
    24061 tattgtaatt tagcaaaaga tgattttcta aagcatggac tgaaactaag acaccatttc
    24121 ctattcccgc aaccaatact aaatgtaata ccgttttatt cttaaccttt ttcttggaaa
    24181 cagcaaaaat taaaattccc agagcagcta agctagcacc agcaactagg gcttgcctct
    24241 cattcttgct tccagtattt ggtaattccg ccagttgatt ttgagaattt aacttataaa
    24301 caagataata agtttcatca tcattctcca cgtatgtcgg aatatcatag acaagctgct
    24361 tcttttcttc tgatgatagc tctgaatctg ccacatattt atagtgaact cccgcagttt
    24421 cttgagcatc cacagatgaa ctagctaata cagacataaa aaataaactt gaaatcgttg
    24481 cagatacaag tcctactgat aattttctaa atgaaaaacg ctcttgtttt tcaccaaaat
    24541 acttttccat tattcctcct tgaaataaaa tttatatatg ttacaaagac ctttattata
    24601 ttagtgtatt atctattatc tatagaaaag gcagtatacc ttaattatac tcttaattta
    24661 caaaaaagtc ttaaaattga gatgcgcttt catactttgt tttatattat ttgggggtac
    24721 aataacacct accatgaaat ttacacggta ggtgttactc atatcactaa tcgttctaaa
    24781 aatggtttga ggcagttgag gagaattcct tctatccagc ttccttgtgc tgatgagcga
    24841 tggtcttcct gcaggctttt ttttagaaaa tctcggactt gttctggtgc gatttcaaat
    24901 tcaaaggctt tcattttata gaaaaagtcg atgagatgat ctgacaggta ttcagttgaa
    24961 aagggtactt caccattttt tcgatattct aataagagcc tagaaaatcg agctttttct
    25021 tcaggaagct cacgaaaata ggaattgagg agccaagtct gcttctgttt tctttcaatt
    25081 ggatcctgac tggcaattcg ttggtctttt tccagctctt tttggtattg tttggccttg
    25141 atagcccgtt ctgctctatt tttaccaaaa agaatttttt cccacttgcg ttcttcttga
    25201 gtcagggtct ctgtaaagcc aaagtaatct tgataagcac gctctgcggg tcccatggct
    25261 agaaccagat tgtctgcata ttgcttggcg attttatccc tcttcttacg ttctttctct
    25321 gcctggatac ggagttcttg ttcgtagtca attttctcct tgcctagctt gacaaggtag
    25381 agttggtcat ccgatttccc aagtaaaaag ggtttgatac acttttcaag gacttcttcc
    25441 atccgagcct ttttctttgg ttccgccttg gtccaacttc ctccctgaaa gacttctagg
    25501 aaaagctggt agtctctctc aggcgcaaat tgattgccac gattgggttt gaaaacacct
    25561 ttttcccaga gccattttag aagtcgctcg tcaaagtcac ttttattgac cttgattttt
    25621 tcctttttct gagcttttct ggttagattt tcaacctttc tgagcagttt ttcttcctct
    25681 tccaattgct ggtcaaggga caatcgatga aaatgacgaa cacagtcgct accaattgga
    25741 aagaggcgtt ggcctgtgac accgttaaag agttcataag cgtatttgat ggcatttcca
    25801 cagacacaat tgctacggcc aataccgtta aaaatcaagg aaacttcatt ccattccttg
    25861 gtagcttgtt cccaagtatc cgctttcgaa gcctgtaaaa ctgcatcgtg cagggatttt
    25921 ctaactggaa gtgtcatgag gtctcctttc taatactcaa taaaaatcaa agagcaaact
    25981 agaaagctag ccgcagtcag ctcaaaacac tgttttgagg ttgtagatag aactgacgaa
    26041 gtcagctcaa aacactgttt tgaggttgta gatagaactg acgaagtcag ctcaaaacac
    26101 tgttttgagg ttgtggatag aactgacgaa gtcagtaacc atatatacag caaggcgaag
    26161 ctgacgtggt ttgaagagat tttcgaagag tataagttat acttttacaa cttgaacctc
    26221 gtctttaccg agtaaaatca agtatttttc aatattttca atcgaatagg ctcgtgataa
    26281 agcctcttcg tatagagcta actgaccacg atagcggtct acgagttgac ttggttcatc
    26341 atagcggtct gtcttgtagt cgaacagaac aattttgttt tcgtaaagca gatagccatc
    26401 aaggatacca cggacaacaa agtcttcctg actcttttgg tctcgtttga gcatggagaa
    26461 aggttgctcg cgatagagat ggtcggtatt agcaagaatt tcctgaccga gtgctgtgtc
    26521 aaagaaagca agaattttat caagattgat cttgtctctg acagcttggc tagtttgaac
    26581 ttgtttgagt gtttctgtta ggctagcaag ggttagttgc tggctgaggt caattatctg
    26641 catgagttcg tgagtagcac taccaatctc agctccagtt accttttctt tggttgaaaa
    26701 atctggcaaa tcgaagctga ttttcttgcc tactgactga ccttgaccag caatctcgac
    26761 accttccata tccataactg gttcgtagaa tttcttgatt tgacttgggg tttgaacact
    26821 aggaagttca atagctgcgc ggtgaagagt attataaact tccacctcct tcagcatttc
    26881 cagagcttct ttgatggtat ctgactgacg attgtctgct tgggagctat cttggagagg
    26941 actcttggtt tccaactctc cgatagcttc tctggtcaac tgatcttcgc caataaaacg
    27001 ataactaaag ttgagcttgt ccttagtaaa cactttactg ataacccaaa gccaatcttg
    27061 gaaattccgt gcttgcagtc tagtattgct attcagtttc ccatttttgg ctgctgggta
    27121 ttccttggat tccagctttt cacgagaacc cttgccgaca agatagagct ttttctcagc
    27181 ccgcgtcata gcaacataca gcaaacgcat ctgctcagaa tagcttgcta gctgtaattc
    27241 ctcttcgttc tgcctatagg tcagactagg aatggagagt ttgatggttt taggatagtg
    27301 gtcttctact gcccctgtct ccatcttggc aatatatttg acaccaagac cattctgacg
    27361 actgagaatg acttctgaca tagagtcttg cttgttgaaa tcttgatcca tattgaggat
    27421 aaagacgtaa ggaaactcca gccctttact cttgtggatg gtcatgagct ctactgcatc
    27481 ttttggcggt gcgacggcca cgcttgccaa atcgtgctgg gcttctaaga cttggtcaat
    27541 catacgaata aaacgcgaca aacctttgaa attgctcttt tcaaattgat cagcacgcag
    27601 tgctagggca tagagattgg cctgcctagc aggaccattc ggcaaagccc caacatagtc
    27661 ataataaaaa cggtcgttgt aaatcttcca aatcaagtca tagagagagt gggttttggc
    27721 atacaagcgc caagaagcta ggatatccat gacttgcttt agtttttcag ctagagctgt
    27781 gtgaatcaag cctttttgac tacttgccat tttttgtgca ttgaccagtt tctcatagag
    27841 attttcgtgg actttatcct ctgctttctg aagggacaaa cgtgctagct catcctcatc
    27901 aaaaccaaac attggagact tcataagggc aaccaaggcg tagtcttgca ggggattgtg
    27961 aatgacacga agagtgtcta gcatgacttg cacttctagg gattggagat aattgttttg
    28021 ctctccgtca gttttgacag gaatcccgta ctcagacagg gcgaggagaa tctggtcatt
    28081 gcgactgcgg ctggaggtca gaagggcaat ttccttaaag gcaacacctt tttcttgatg
    28141 aagtttcaga atctccttga taactaagcg catttcgcct gttagtttcg tttctgtttg
    28201 actctcttct tcctcacctg tatcgtcctt gtcgtagagg agaaattctg ccttgttgtc
    28261 tggattggga gtcagtttgg tattggcaaa aacaagctgg tgcttgttat catagttgat
    28321 ttcgccgacc tcttggtcca tgagacgttc aaagacatca ttggttgctg acagcacttc
    28381 tgaactacta cggaaatttt ccttgaggag aatgagcttg ccttcttggg gattttgcgc
    28441 atagcgttgg aatttctcat tgaaaatctg cgggtctgcc tgacggaaac gatagatgga
    28501 ttgcttgata tctcccacca taaagcgatt gtggccatta gacaacaatt ccagcatccg
    28561 ttcttgaata tggttggtat cctgatactc atcgaccatg acttcatgga agcgctcctg
    28621 ataagactca cgaacttgtg ggaaattctc taaaatctca atggtgtaat ggctgatatc
    28681 agcgaattca aaggcatttt cctggcgttt gcgctgacga taagcctcca caaaatgact
    28741 cataaaggtt tggaaggttt tagctagttc ccatgtgtct tgatgataac gttcttgata
    28801 gtcgagaatg gttatctggt ctgataattg tcctagttta gcaaactggg tctttctctc
    28861 ttcgttgtag gcatcagcca ggggcttcaa atcagcctta cgactggcat tagtcagggc
    28921 tcgaccgttt ttctccttag agatggcgac aacacgcgca agcactgcct gataagcctg
    28981 actatcggac tcctgattta gggagccaat ttcatccaga attaactgaa cattttctaa
    29041 ataggcagcc tttgcaaact ccttggcatc gttatccaga tggtaacgga aaaagctttc
    29101 caaatcccaa agggcttgtt tgatttgctc agtcagtttt tctttttcac tggtaaaatc
    29161 agctttctca aagcctttga ggaaagattc actcagccac ttttgaggat tactggtgga
    29221 ttggaggaag tcatagattt tatagacctg ctggcgcaga ccccgttcgt ccttgccacg
    29281 cccagcaaag tttttcagca aatgactaaa ggtctctttc tgtttacctt ggtaatgcgc
    29341 ttcaaagacc tcatgaaaga cttcgttttc gagaagaagt tgctcgcttt ggttttgtaa
    29401 aatacggaaa ttaggtgcaa tatcaagcag ataaccatgt ttgccaagga atttttgtgt
    29461 gaaagagtcc atggttccga tggcagcgtt tggtaggtct gccaactggc gtcccaagtg
    29521 ttgtttgagg tcgacatcat ctgtttcttg gattttcttg ctgatttttt tctctaaacg
    29581 ttctttaagt tcatttgcag ccttgacggt aaaggttgag ataaagagtt gagaaatttc
    29641 gacaccacgc gccaattggt ccagaatgcg ctctgccatg acaaaggtct ttccagaacc
    29701 agccgatgct gagaccagga tattctggcc agaagtgtag atagcttcga tttgctcggc
    29761 agttttcttc tgttccttgc tcgaatttgc ttctgcttct tgcagttttt gaatctcctc
    29821 ctcacttaaa aagggaataa gcttcatcga ttcaactcct ctcttatttt ttcaagccaa
    29881 gcttgcttga gtttttctcc gaccagacgc ttgccatcag ctaggtccaa cttttctagg
    29941 aaacgggctt ggcccagatg gtaattggct tcaaagcctg taatagcctg atgttgctgg
    30001 acgtatgggg caatgcttct gccattttca gtataaggat tgatggcgaa ccggcctgct
    30061 aaaatcttct cagcagcttt cttgtaaaga taggcattgt agtccagtag gagctgaaat
    30121 tcctcatctg tcagttgatt cgccttgttt ttgttataaa attcgcctaa ataactgctt
    30181 tctttttcca agaagagccc ttggtatttc atagatttgc tggcttctac cactgctcct
    30241 gccagacttt ttaccgccat cagagattgg acaggttcag ccatttccaa gtacatggcg
    30301 ccgaaaaaat tctgctcccc ttctcttttt agggcagcaa gataggttgg taactgagaa
    30361 ttgagcccat taaagaaatg aggaaactgg aactgagtta gactcgactt gtagtctact
    30421 actcctatcg ctccatcagc tttcaaacgg tcaatccggt ccaccttacc tcgtacaaag
    30481 acactgcgtc cattgtccaa ttgaataaag gcttgctctt tcccaccgaa atttgcctct
    30541 tctttaatgg tttcgatgac tggattatgg cggagaatgt gaccagtcgt ccgtgcaaca
    30601 tcaagcaaaa cttctttggt aaactgggct tccaaacttt cttgataaat agcttcaaat
    30661 tcgcgttctt gactagtttc ttgaatagct tgttctagac ggttgtcaaa ggaatcttca
    30721 tcaggcaact gcaaggcacg ttcaaaaatg cggtgcaaga aatttccatg actgcgagca
    30781 tccggacgca aacgtaattc ctcctgcaag cctaacacgt agcggaggaa ataactgtat
    30841 tggtttctgt aaaactcggt caaaccggac gtagataggt aaaattcctg ttcagcagga
    30901 tagagagctt gtaaggtatc tttggtcaac tgcttactgc ttggactggt tggaagggca
    30961 ggattttcca aaccttgctg gtctagtttt ttacccatca cacgcgccag aaccttgaca
    31021 aaggtcaaat cttgctcagt atcactcgtc tcgccctgct ggtgataggc aaccagactg
    31081 gacaaaagac tgtgatagga tcccatatct tccttagaca gccttttgtg attcatcctc
    31141 ttctcttttc gactaaatcc caaatggacc aactcttgaa gataggctga ctccttgctt
    31201 tcactttcat taaaaaggct tggagccgac aaaactaatt gcttacgggc agaattgacc
    31261 aaagaaagca tagtgtagtg atttttcttg agattttcac tgctggcaat cagtaattga
    31321 acgccttctt cggtcgcttg gtttatgttt tgtctttctt catctgtcaa aagactggta
    31381 ttttgcgcga tttttggtaa attgtcctga gttagcccaa tggcgtagac aaagtcagca
    31441 gtcaaaggcg caatcaaatc gtaactctgc accagaacgg tgtccactgt cgctggaata
    31501 gtgcgatact gagacaaact cattccagaa tggagcaagg ctaggaagtc ctctagacta
    31561 atctgtgaac cagcaaaaac agtcgcaaat tgttctaaaa catgacagaa tgccttccaa
    31621 acctcggctt gtctttcctg ttctatagct tccatagtgg ctgtcaaatc ttgtaactgc
    31681 ttggtcacca ctccttcttt tagaaagaca ttccactttt gcaagagatt ttcggccttt
    31741 tgttttcggc tagcaaagag ggtttcaaga ggtgctaaaa ttctcagacg gaggacattc
    31801 aaacgctcaa gattaaattt tccatggtgg gatttggtga aggtttgctg aaaggctggc
    31861 aagccattga taccaagata gcggatatat tgctcaaaag catcaatatc agactgactg
    31921 aggtcagtat acaaatcagt tctaagaaga ttagtcaaat cctcctgacg aaaacggtaa
    31981 cgttttaaag ctaaaataga ctcgacaaac tgagtcaagg gatgatgagc catggcttcg
    32041 cttctaccaa gataaaaagg aatctgatac tggtcaaaaa tggttttgag agataactgg
    32101 taagaagcta catcccccaa gagaatacga aaatgcttgt agctcaggtc tgagttctca
    32161 tgtaatttct gacgaatact acgggctact agctccaact cctccttttg cgtcaaacaa
    32221 gaccagattt gtaaattttc acggtctttc tcatcgacat ccaaagcgag ttctgaaaag
    32281 tcataagaag actccaacaa acgagaggcc ttgtcaaaac tatccatctt ctcatgggtt
    32341 tgagaacagt cctgagcagg cgtttggtat ttagaagcca gatgatggag aaattttacg
    32401 ctggcttggt agagattgcc ctcgctaaaa ggactggtat aggctttctt actagcataa
    32461 gccccgataa caatctcaac acctttgccg tgaagtaagt ccacaacccg ctcttcctca
    32521 gcagaaaaac gagtaaagcc gtcaatgacc aaggcgattt gattaaaatc actacttatc
    32581 ttgtcattct caatagcctc aatcaaatgg gacaactgac ttccctgggc taactgacct
    32641 tgattaagat aggctgttac tttctcaaaa atcaagagta aatccgccct cttatcctca
    32701 tctgttaaat tctccaagtc caaaaaattc atctgagatt tggtcatctc atggtaaagc
    32761 tcaattaact gctggatcaa ttgaggatcc tgcttaatag cgccataaac acgcaagtcc
    32821 ttgggatcga gttcggcaag gcatttgtaa aaggccaacc caagaccgat atcatcaaga
    32881 gtagttttag ctggtaaatc attcaagacc agataacgag ccatttgagc aaagcgcgtg
    32941 acggtaatcg aaaaagaagc ctgctgggac aagcattcca gcacggcgcg ttccttttca
    33001 aaagaaagag agttgggggc aatgtagaag acccgcttgc cagctgcaac tagctcttct
    33061 gcctctcttg ttagaatttc tgtcaaagaa gtccgaatat cagtataaag taatttcatc
    33121 tcagcctcgt tggaattttt catcacccta tattatacca tgattagcct cgtaaatctg
    33181 ttaaaatatt taggccatcc tttcttttct tcatcatctg ctaaatctta aatacttagc
    33241 tttacttgta ttagatagaa taagtctggc tactgaaaat catataataa aaaagcctcg
    33301 gtaacaaggc tttgagtttt atgattgttt cttaggtacg gaatacactt caatgtgttg
    33361 tcccagtgtc ttaatgtcga cgggtagatt gtctgattta tcgccatcaa catcggactc
    33421 taattcgata tcagaagaag ttttaatatc acgtgccttt atatattcaa tattcttgat
    33481 agaatgattg aactatagta aattgaaact ataatagtac accgtggatg ctaaaatatt
    33541 gctagaaatt aatttgattt ccctaatcaa gctgttcgta tcttatttca atctactata
    33601 gtaaaatgaa ccaaaaatag tacacaatgt ggtataatct t
//
LOCUS       DAVMBH010000021        33287 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVMBH010000021 DAVMBH010000000
VERSION     DAVMBH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.021"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            69..566
                     /locus_tag="VYP30_001092"
     CDS             69..566
                     /locus_tag="VYP30_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1808105.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            566..2221
                     /gene="dnaX"
                     /locus_tag="VYP30_001093"
     CDS             566..2221
                     /gene="dnaX"
                     /locus_tag="VYP30_001093"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1808106.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2249..2443
                     /locus_tag="VYP30_001094"
     CDS             2249..2443
                     /locus_tag="VYP30_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1808107.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2593..3363
                     /gene="sufC"
                     /locus_tag="VYP30_001095"
     CDS             2593..3363
                     /gene="sufC"
                     /locus_tag="VYP30_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1808108.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3391..4653
                     /gene="sufD"
                     /locus_tag="VYP30_001096"
     CDS             3391..4653
                     /gene="sufD"
                     /locus_tag="VYP30_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1808109.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4664..5890
                     /locus_tag="VYP30_001097"
     CDS             4664..5890
                     /locus_tag="VYP30_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1808110.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSSVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5877..6317
                     /locus_tag="VYP30_001098"
     CDS             5877..6317
                     /locus_tag="VYP30_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1808111.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDII
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6371..7783
                     /gene="sufB"
                     /locus_tag="VYP30_001099"
     CDS             6371..7783
                     /gene="sufB"
                     /locus_tag="VYP30_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1808112.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8014..9255)
                     /locus_tag="VYP30_001100"
     CDS             complement(8014..9255)
                     /locus_tag="VYP30_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1808113.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9358..10467
                     /locus_tag="VYP30_001101"
     CDS             9358..10467
                     /locus_tag="VYP30_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1808114.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRIQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDCLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11113..11460
                     /gene="ssrA"
                     /locus_tag="VYP30_001102"
     tmRNA           11113..11460
                     /gene="ssrA"
                     /locus_tag="VYP30_001102"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11630..11717)
                     /locus_tag="VYP30_001103"
     tRNA            complement(11630..11717)
                     /locus_tag="VYP30_001103"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11681..11683),aa:Ser,seq:gga)
     gene            11879..12619
                     /locus_tag="VYP30_001104"
     CDS             11879..12619
                     /locus_tag="VYP30_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1808115.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12616..13527
                     /gene="pfkB"
                     /locus_tag="VYP30_001105"
     CDS             12616..13527
                     /gene="pfkB"
                     /locus_tag="VYP30_001105"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1808116.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13524..15476
                     /locus_tag="VYP30_001106"
     CDS             13524..15476
                     /locus_tag="VYP30_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1808117.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTIGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15640..17865
                     /locus_tag="VYP30_001107"
     CDS             15640..17865
                     /locus_tag="VYP30_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1808118.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17910..18338)
                     /locus_tag="VYP30_001108"
     CDS             complement(17910..18338)
                     /locus_tag="VYP30_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808119.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18476..19618
                     /locus_tag="VYP30_001109"
     CDS             18476..19618
                     /locus_tag="VYP30_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1808120.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19627..20841
                     /gene="thiI"
                     /locus_tag="VYP30_001110"
     CDS             19627..20841
                     /gene="thiI"
                     /locus_tag="VYP30_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1808121.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20976..21789
                     /locus_tag="VYP30_001111"
                     /pseudo
     CDS             20976..21789
                     /locus_tag="VYP30_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21811..22146
                     /locus_tag="VYP30_001112"
     CDS             21811..22146
                     /locus_tag="VYP30_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV1808122.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVGLMA"
     gene            22143..22550
                     /locus_tag="VYP30_001113"
                     /pseudo
     CDS             22143..22550
                     /locus_tag="VYP30_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22563..23729
                     /locus_tag="VYP30_001114"
     CDS             22563..23729
                     /locus_tag="VYP30_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1808123.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNEVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFEPQYCLATSRRANAHYVY
                     SEENLLAKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE"
     gene            24063..25556
                     /locus_tag="VYP30_001115"
     CDS             24063..25556
                     /locus_tag="VYP30_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1808124.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESNAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPIRDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25569..26462
                     /locus_tag="VYP30_001116"
     CDS             25569..26462
                     /locus_tag="VYP30_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1808125.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNHNLLVR"
     gene            26536..29887
                     /locus_tag="VYP30_001117"
                     /pseudo
     CDS             26536..29887
                     /locus_tag="VYP30_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            30131..30232
                     /locus_tag="VYP30_001118"
                     /pseudo
     CDS             30131..30232
                     /locus_tag="VYP30_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(30473..30943)
                     /locus_tag="VYP30_001119"
     CDS             complement(30473..30943)
                     /locus_tag="VYP30_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1808126.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(30960..33233)
                     /locus_tag="VYP30_001120"
     CDS             complement(30960..33233)
                     /locus_tag="VYP30_001120"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1808127.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPRKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCHAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        10002 a         6008 c         7294 g         9983 t
ORIGIN      
        1 aaaatccttt gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata
       61 atagttctat gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt
      121 ccttcctatt ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca
      181 taaaatcacg ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat
      241 tggttttagg tcccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg
      301 tttgtggtga ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc
      361 tcaactatat ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga
      421 atggtcagtt acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta
      481 tggatcgaga ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact
      541 ttacgatgtt tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca
      601 aaacttctcc cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga
      661 gcaagagaaa ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag
      721 tgttgctaaa atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg
      781 caataactgc tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat
      841 ggatgcagct tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta
      901 tgcgcctagc cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac
      961 aggggctttt aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat
     1021 tttggccact actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt
     1081 tgagtttaaa tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa
     1141 agaaaatatc agttctgaac cagaggctgt ggaaatcatt gccagacggg cggaaggtgg
     1201 aatgcgggac gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct
     1261 gacgactgct atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta
     1321 tgtggcggcc ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt
     1381 tgacaatggt aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt
     1441 gttaattgtt caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt
     1501 ggcacttcct caaaaaaatc tgtttgaaat gattcgctta gcaacagtga atttagcaga
     1561 tattaagtct agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga
     1621 aatcaagccc gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca
     1681 ggaagttgcc cgtctcaaac aagagctttc taatgcaggt gcggttccta aacaagttgc
     1741 accagctcct agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt
     1801 gcaatctatc ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg
     1861 tttgcagaat gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct
     1921 agttggttct caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa
     1981 cttcaatgct ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct
     2041 cagtcaggcg gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga
     2101 agttcgcgca gccttttcag ccaaagccaa atcttctcaa actgaaaaag aagtagaaga
     2161 aagcctgatt ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta
     2221 aagaaagatt tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct
     2281 atttacagct gctgagacct attttttcaa tgaagcctgg atgactggcc gctatattat
     2341 ggcagccttt tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggtaa
     2401 aatcgttgat gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca
     2461 aaatcaaagc cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt
     2521 gctctatttc tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag
     2581 aaaggaacta tcatgtcagt aatagagatc aaagatcttc acgttgagat tgaaggaaaa
     2641 gaaattttaa aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga
     2701 ccaaatggta caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa
     2761 gtaactaaag gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag
     2821 cgtgcgcgta tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc
     2881 aatgctgagt ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca
     2941 gttcgtgagt ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa
     3001 atggcagagc gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt
     3061 cttcaacttt tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt
     3121 gatattgacg ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt
     3181 ggtgctatga tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta
     3241 cacgtgatga tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg
     3301 gaacgtgaag gatacgcaaa actagctgaa gaacttggct acgactacaa ggaagaattg
     3361 taattccctc gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca
     3421 gaaatgcacg ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt
     3481 gagactttgg aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat
     3541 ggaacgatta cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat
     3601 cacttgaagt tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta
     3661 gctgaacagg gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg
     3721 atcgaagaat tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac
     3781 acagcttact ttaacagtgg tgctgtactc tatattccag ataacgtaga aatcacagag
     3841 ccaattgaag gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt
     3901 atgattatcg ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt
     3961 gaaggaagtg acaaagtaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg
     4021 caagtcaagt ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt
     4081 cgtggtaaat taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga
     4141 aatgtcgttg ctgattttga tagtgacttg attggtaatg gtagccatgc tgacctcaag
     4201 gttgtagctc tttcaagtgg tcgtcaggta caagggattg atactcgtgt aactaactat
     4261 ggctgcaact ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg
     4321 actttcaatg gtatcggcca catcatcaag ggtgctaagg gagcagatgc gcaacaagag
     4381 agccgtgttc tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt
     4441 gatgaaaatg atgtcactgc aggacacgca gcgtctatcg gacaagttga tccagaagac
     4501 atgtattacc tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt
     4561 ggtttccttg gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt
     4621 gcaactatcg aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc
     4681 gattcgcaag gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct
     4741 ggacaatgct gcgacgacac aaaaaccact agtagttctg aaagctatta acagttacta
     4801 tgagcaggac aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc
     4861 ttcttatgaa gctgctcgtg aaaccattcg taagtttatt aatgcaggct ctacaaagga
     4921 agttctcttt accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga
     4981 aattctcgct gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat
     5041 tccatggcag gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga
     5101 cggtgccttg gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc
     5161 cctagctcat gcctccaatg ttcttggtgt ggtcaatccg atcaaggaaa tcactcaatt
     5221 agcccaccaa gttggggcaa ttatggtagt ggatggtgct caatctacac ctcatatgaa
     5281 gattgatgtc caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg
     5341 tccgactggt atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt
     5401 agaatttggc ggcgagatga ttgattttgt ctacgagcaa tctgctagtt ggaaggaatt
     5461 gccttggaaa tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc
     5521 agttgattat ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattaat
     5581 tgcgtacgtc tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga
     5641 tttggctcaa cgttcgagtg ttattgcctt taacctaggt gatctccatc ctcacgatct
     5701 tgcgacggct ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc
     5761 cttgcttcag tatttggaag tcccagcaac agctcgtgca agtttttata tctacaatac
     5821 caaggcagat tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg
     5881 cactttctaa actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac
     5941 atcaccaagg gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtgggg
     6001 atatcatcaa cctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc
     6061 taaattcagg atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag
     6121 gaaaaaccaa acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc
     6181 aaaaagatga gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat
     6241 tccctcaaag aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa
     6301 atcaagaaaa acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag
     6361 aaaggatatt atggctgaag aaagagtaga accaaaacca attgaccttg gtgaatataa
     6421 atttggtttc catgacgatg tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg
     6481 tgttattcgt gaattatctg ctgctaaggg tgagcctgag tggatgttgg agttccgttt
     6541 gaagtcttat gaaaccttca aaaaaatgcc catgcaaact tggggagcag acttgtcaga
     6601 gattgacttt gatgacttaa tctactatca aaaaccatct gacaaaccag cccgttcttg
     6661 ggatgatgta cctgaaaaga ttaaagaaac ctttgaacgt atcgggattc cagaagctga
     6721 acgtgcttat ttagcagggg cttctgccca gtacgagtca gaagtggttt accacaacat
     6781 gaaggaagag ttccaaaaat taggtattat ctttacagat acagattccg cactcaagga
     6841 atacccagac ttatttaaac aatactttgc gaagttggta ccgccgacag ataacaagtt
     6901 ggcagccctc aactcagcag tatggtcggg tggaactttt atctacgttc caaaaggtgt
     6961 caaggtagat attccacttc aaacttattt ccgtatcaat aacgaaaata taggtcagtt
     7021 cgaacgtacc ttgattatcg ttgatgaggg agcaagcgtc cactacgtag aaggatgtac
     7081 agcaccaaca tattcaagca atagcttaca cgctgccatt gtagaaattt ttgctttgga
     7141 cggagcttat atgcgttata caactatcca aaactggtct gataacgtct ataacttggt
     7201 aacaaagcgt gctaaggctc aaaaggatgc cactgttgag tggattgatg gaaacttggg
     7261 tgccaaaacg actatgaaat atccatctgt ttaccttgat ggagaaggag cgcgtggtac
     7321 catgctctct atcgcctttg ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat
     7381 tcacaatgct ccacatacca gctcgtctat tgtgtctaaa tctatcgcta aaggtggagg
     7441 aaaggttgac taccgtggac aagtcacctt taacaagaac tctaagaaat ctgtttccca
     7501 cattgaatgt gataccatta tcatggatga cttgtcagca tcagatacta ttccatttaa
     7561 tgaaattcac aactcgcaag tggctttgga acacgaagcc aaagtatcta agatttcaga
     7621 agagcaattg tattatctca tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat
     7681 tgtcatggga tttgtagaac cctttacaaa agaacttcca atggaatacg cagttgagct
     7741 gaaccgcttg attagctatg aaatggaggg atcagttgga taaaatttga ttttatactc
     7801 ttcgaaaatc tcttcaaacc acgtcagcat cgccttaccg tatgtatggt tactgacttc
     7861 gtcagtttca tctacaacct caaaacagtg ttttgagcaa cctgaggcta gcttcctagt
     7921 ttgttctttg attttgagta ttagatttac tcaaaatcaa ggattttgaa gatgaacttg
     7981 tatcaaaaaa tcgcggttta aaatcgcgat tttttataat ttctcgttaa caaagcggac
     8041 aaactgattc caccaaactt ttaagaagaa ggctttttca attttcttgt ctgctaccat
     8101 ttcgaaacta gggcgctctg tggtgatgta accttgacca atcaagtcct tgtcttcata
     8161 agtcaaatgg ccaaccactg ttccagcttc aagtggtgct gggattgctt tggaatcagg
     8221 tgtgaattga acagattggg aagattgatt cccaacacgt tcgattagat agatatcctc
     8281 tggagccact gcagttactg tatcttcttt tccatcttgt acaggggctt tgctatcttg
     8341 ataggcatcg ccttgttgaa cgattttgcg aagtgtaaat gtagaagaaa tataatccat
     8401 tagggaagat gtagctgtaa atcgagcgta aggattattg tcttgatgat ctgcatttaa
     8461 aacaactgtg atgactctca tgcctttttc gacagtagta ccaacaaaag actctccagc
     8521 cttatctgtt gttcctgttt ttagcccatc aaaaccacca cggtaagcag gcataccttc
     8581 taacatgtag ttggttgaag tgattgtcat cccagcaaaa gtagaagaag gttttttggt
     8641 gatttctaag acttgtgggt attttttgat gaggttgcga gcaacgatag cgacatcata
     8701 agcactaagc ttattttcct catctttttt agaacctggg taaatgttat cccctagagt
     8761 ttcattgtta agacctgtcg tattgacaac agtggcatcc tgaattcccc attccaagag
     8821 ttttgcccgc atcatatcga cgaaatcttt ttctgagcca gcaattttct cagctagggc
     8881 aatagcggcg ctgttggcac tagataccag agttgcttca agcaactctt cgacagtata
     8941 attacgggcc tccataggaa tattactggc ttcagaattt gtcgtcaatt gataaggata
     9001 atcagaaata tctacaggag tggagagggt aatacttccg ttttccaaag cttcatagac
     9061 cagataaaca gtaatcaatt ttgttatgga agcaatttcg acaggttgcg ttgcatcctt
     9121 ctcatagaga attttaccag tatttgcctc aacagcaatc gcatgtttag cggcaatggt
     9181 aaaatcttga gcaacagcag tagaagcacc ccctaaaaga gagacagtta acaaagttaa
     9241 aaatattttt ttcatagtag tcttattcta tcataaagaa aaaaaatatt cttgctttaa
     9301 taattcatct gttaagcttt ttgaaaatat ggtaaaataa agtgagggag gtaactcatg
     9361 tttcgtagaa ataaattatt tttttggacc acagaaattt tactcttaac catcatcttt
     9421 tacctatgga gacagatggg gtctttgatt aacccttttg ttagcgtgct taatacaatt
     9481 atgattccat ttttattagg gggctttctt tattatttga caaaccctat tgttactttc
     9541 ttaaataaag tctgtaaact caatcgtttg cttggtattt taattacctt gtgtactttg
     9601 gtctggggaa tggtcatagg tgttgtctat ctcttaccta ttttgattaa tcagttatct
     9661 agtttgatta tatctagtca aactatttat agtcgaatac aagacttaat catagactta
     9721 tctaattatc ctgcgctcca gaatttggat gtagaagcta caattcagca gttaaactta
     9781 tcctatgttg atattcttca aaatatccta aatagcgtat caaatagtgt ggggagcgtc
     9841 ttgtcagctc ttatcagtac tgttttgatt ttgattatga ctccagtttt tttggtttat
     9901 ttcttattag atggacataa attcttgccc atgcttgaaa gaacgattct aaagagggat
     9961 tgcttgcata ttgcaggctt attaaagaat ttaaatgcga cgattgctcg ctatattagt
    10021 ggagtttcga ttgacgcaat cattataggt tgtttagctt atattggcta tagtattatt
    10081 ggtttaaaat atgctttagt ttttgccatt ttttctggtg tagccaattt aattccttat
    10141 gtggggccaa gtattggttt gattcctatg atcatcgcaa atatattcac tgatcctcat
    10201 agactgctga ttgcagtgat ttatatgctt gttgttcagc aggtagatgg caatatctta
    10261 tatcctcgaa tcgtaggaag tgttatgaag gttcatccaa tcacgatttt agttttactt
    10321 ttgttgtcaa gcaatatcta tggtgtagtt ggaatgattg tcgcagtgcc aacctattct
    10381 atcttgaaag aaatttctaa gttcttatcc cgtttgtatg aaaatcataa aataatgaaa
    10441 gaacgagaaa gagaattagc taagtaaaag tcaggagaac cctgattttt ctttactgga
    10501 agtggccttt agattagaag actgaaaata agttaaagtc ttaaactaat tttcacagct
    10561 aagaatagta gaagttaatc tgataaaaat cgaaaaaacc agtggaattc tgtgtcaggg
    10621 taagttccac tggttttcat agtctattaa agttcgaatg aaacctattt atagtatatt
    10681 gaaactagaa tagtacacct ctaattctaa aacattgtta gaaatcgatt tgactgtcct
    10741 aatctattcg tcctattctt atttcatttt actatatttt ggtgcaataa gtgaaaagta
    10801 gtccgaataa tataaggatt gattttatag tttttaaact caaatgaatt aaaataaaga
    10861 gagtacgaaa attctcatct gaaagtattt tagaataatt ctcttcgtga atttcttcaa
    10921 aacagatagc ttcatcttag gtatgtgtta attggatttc gtaagctcta tttacaatcg
    10981 taaagttatg cactgagaaa gttgtagtta gtcttccagt ttgctaaatt tctcgaatag
    11041 tatctttttt aggtatgtga tttctttttg catttttgag ttagataagg tataatagtt
    11101 ttattgtctt ttggggtcgt tacggattcg acaggcatta tgaggcatat tttgcgactc
    11161 gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa aataacactt cttacgctct
    11221 agctgcctaa aaaccagcag gcgtgacccg atttggattg ctcgtgttca atgacaggtc
    11281 ttattattag cgagatacga ttaagccttg tctagcggct tgataagaga ttgatagact
    11341 cgcagtttct agacttgagt tatgtgtcga ggggctgtta aaataataca taacctatgg
    11401 ttgtagacaa atatgttggc aggtgtttgg acgtgggttc gactcccacc ggctccatta
    11461 ttcctttgca ttcttttgca ttccttggta aaacgttgtt aaatcaacgt tttttatttt
    11521 tatatttggt attcctttgc attcttttgc taaaaaggga gtcacaaaca gaccctattt
    11581 taaaaaagga tacaacattt gtcgcatcct aaaaataatc ttttttcgac ggaagacatg
    11641 ggattcgaac ccacgcacgc tattacacgc ctaccgcgtt tccaacacgg cctcttaagc
    11701 ctcttgagta atcttccaat acttactcaa atagtctacc ataaaggctc ttatcttgca
    11761 ataaaaattc tagaaataag aaaaatgata gattttgaaa gaaaatgaca aaaaatgctt
    11821 gacttcgaaa taaagtatgg tagaatgaat agtgtaaacg ataacaggag gtgattcagt
    11881 gttaaaaaca gaacgtaaac aactgatttt agaggagtta aatcaacatc atgtagtttc
    11941 tctagaaaaa ttagttagtt tgctagaaac gtcagaatca acggttcgaa gagacttgga
    12001 tgagttggaa gcggaaaaca agcttcgtcg tgtgcatggt ggagcagaac tcccccactc
    12061 cttacaggaa gaagaaacca ttcaagaaaa atctgtcaaa aaccttcaag aaaagaagtt
    12121 gctggctcag aaagcagcct ctctcattaa agaaaaagat gtcatcttta tcgatgctgg
    12181 aacaacaact gcttttttga ttcatgaatt ggtcaataag aatgttacag ttgtgaccaa
    12241 ctccattcac catgctgctc agttggttga aaagcagatt ccaactgtca tggttggagg
    12301 aaacgtcaag acggcgacag atgctagtat cgggggcgtt gctcttaacc agattaacca
    12361 attgcacttt gaccgtgcct ttatcggaat gaatggtgtt gacgatggct attatacgac
    12421 tcctgatatg gaggagggag ctgtgaaaag agctattttg gagaatgcca agcagaccta
    12481 cgtcttggtg gattcgtcaa aaattggaca aacttgcttt gccaaggtag caccactcaa
    12541 acgcgctatc gttatcacta gtcaagggca tgagctcttg caggttatta aggagaaaac
    12601 ggaggtaata gaagtatgat ttatacagtc acactcaatc catccattga ctatatcgtt
    12661 cgtttggacc aagtcaaagt tggtagtgta aatcgtatgg acagtgatga taagtttgct
    12721 ggtgggaaag gaatcaatgt cagccgtgtc ttgaaacgtt tgaatatacc aaatacagcg
    12781 acgggattta tcggtggctt tactggtaaa tttatcacag atactttagc agaggaagaa
    12841 atcgagacac gttttgtcca ggtggcagaa gatactcgta tcaatgttaa aatcaaagca
    12901 gaccaagaaa cagaaatcaa cggaacgggt ccaactgttg aaccggttca gctagaagaa
    12961 ttgaaagcta ttttatctag tctgacagca gaagatacag ttgtctttgc aggttcaagt
    13021 gctaaaaatc taggcaatgt tatctataag gatttgattt ccttgacgcg ccagactggt
    13081 gcgcaagtgg tctgtgactt tgaaggacag accttaattg atagtttgga ctaccagcct
    13141 cttcttgtaa aaccaaacaa tcatgaactt ggagcgattt ttggggttaa actcgaaagt
    13201 ttagatgaaa ttgagaaata cgctcgtgag ttactggcta agggtgctca aaatgttatt
    13261 atctctatgg ctggtgatgg cgcccttctt gtcacatctg agggagctta cttcgctaaa
    13321 ccaatcaaag gaacagtcaa aaattcagtt ggagctggtg attctatggt tgctggattc
    13381 acaggtgaat ttgtcaaatc aaaagacgca gtagaagcct tcaaatgggg agtggcttgc
    13441 ggaacggcaa ctaccttctc agatgacttg gcaacggcgg aatttattaa agaaacatat
    13501 ggaaaagttg aggtagaaaa aagatgaaaa ttcaagacct attgagaaaa gatgtcatgt
    13561 tgctagattt gcaggcaact gaaaaaacag ctgtcatcga cgagatgatt aaaaatttga
    13621 cagagcacgg ttatgtaaca gattttgaaa catttaaaga aggaattttg gcgcgtgaag
    13681 ctttgacttc tactggtttg ggtgatggaa tcgcaatgcc tcacagcaaa aacgctgctg
    13741 tcaaagaagc gacagttcta tttgctaagt caaataaggg tgttgactac gagagcttgg
    13801 atggacaagc aactgacctc ttcttcatga ttgcagctcc agaaggtgcc aatgatactc
    13861 acttggcagc cttggcagaa ttgtctcaat acttgatgaa agacggtttt gcagacaaac
    13921 ttcgtcaagc aacatctgca gaccaagtta tcgaactttt tgaccaagct tcagaaaaaa
    13981 ctgaggaact tgttcaagca cctgctaatg actctggtga ctttatcgta gctgttacag
    14041 cttgtacaat aggtattgcc cacacttaca tggcccaaga agcccttcaa aaagtagctg
    14101 ctgaaatggg ggttggtatc aaggtcgaaa ccaacggtgc tagcggtgtt ggaaatcaac
    14161 taactgcaga agatatccgt aaggctaaag ctattatcat tgcagcagac aaggccgttg
    14221 aaatggatcg atttgatgga aaaccattga tcaatcgtcc agttgctgac ggtatccgta
    14281 agacagaaga gctaattaac ttggctcttt caggagatac tgaagtctac cgtgccgcta
    14341 atggtgccaa agctgcaaca gcctctaacg aaaaacaaag ccttggtggt gccttgtaca
    14401 aacacttgat gagtggtgta tctcaaatgt taccattcgt tatcggtggt ggtatcatga
    14461 ttgcccttgc cttcttgatt gacggtgctt tgggtgttcc aaatgaaaac cttggcaatc
    14521 ttggttctta ccatgagtta gcttctatgt tcatgaaaat tggtggagct gcctttggtt
    14581 tgatgcttcc agtctttgcg ggttatgttg cctactctat tgctgaaaaa ccgggtttgg
    14641 tagcaggttt cgtggctggt gctattgcca aagaaggttt tgcctttggt aaaattcctt
    14701 atgccgcagg tggtgaagca acttcaactc ttgcaggtgt ctcatctggt ttcctaggtg
    14761 cccttgttgg tggatttatc gcaggtgcct tggttcttgc catcaagaaa tacgttaaag
    14821 ttcctcgttc actcgaaggt gctaaatcaa tccttctatt gccacttctt ggaacaatct
    14881 tgacaggatt tgttatgcta gctgtgaata tcccaatggc tgcaatcaac actgctatga
    14941 atgacttcct aggcggtctt ggaggaggtt cagctgtcct tcttggtatc gtccttggtg
    15001 gaatgatggc tgttgacatg ggtggaccag ttaataaagc agcttatgtc tttggtacag
    15061 gtacgcttgc agcaactgtt tcttcaggtg gttctgtagc catggcagca gttatggctg
    15121 gaggaatggt gccaccactt gcaatctttg tcgcaactct tcttttcaaa gataaattta
    15181 ctaaggaaga acgtaactct ggtttgacaa acatcatcat gggcttgtca tttatcactg
    15241 agggagcgat tccatttggt gccgctgacc cagctcgtgc gattccaagc ttcatccttg
    15301 gttcagcagt agcaggtgga ctcgttggtc ttactggtat caaactcatg gcgccacacg
    15361 gaggaatctt cgttatcgcc cttacttcaa atgctctcct ttacctcgtt tctgtcttgg
    15421 taggagcaat cgtaagtggt gtggtttatg gttacctacg caaaccacaa gcataaaaaa
    15481 tagaaaaatg aaaagattgg accgtttggt gcagtctttt tctcttcccg aaatgcctgt
    15541 gaaatatggt ataatagaag aatggcaaac aagaatacaa gtacaacaag acggagaccg
    15601 tctaaagcag aactggaaag aaaagaagcg attcaacgaa tgttgatttc gttaggaatt
    15661 gcgattttat tgattttcgc agccttcaaa ttaggggctg caggtataac cctttataat
    15721 ttaattcgct tgctagtggg tagcctagct tatctggcga tattcggcct attaatctat
    15781 ctcttctttt tcaagtggat acgaaaacag gaaggactct tatctggctt tttcaccata
    15841 tttgctggct tactcttgat ttttgaggcc tacttggttt ggaaatatgg tttggacaag
    15901 tccgttctaa aagggaccat ggctcaggtt gtgacagatc tgactggttt tcgaacgact
    15961 agctttgctg gagggggctt gatcggggtc gctctttata ttccaacagc ctttctcttt
    16021 tcaaatatcg gaacttactt tattggttct atcttgattt tagtgggttc tctcctagtc
    16081 agcccttggt ctgtttacga tattgctgaa tttttcagta gaggctttgc caaatggtgg
    16141 gaagggcacg agcgtcgaaa agaggaacgc tttgtcaaac aagaagaaaa agctcgccaa
    16201 aaggctgaga aagaggctag attagaacaa gaagagactg aaaaagcctt actcgatttg
    16261 cctcctgttg atatggaaac gggtgaaatt ctgacagagg aagctgttca aaatcttcca
    16321 cctattccag aagaaaagtg ggtggaacca gaaatcatcc tgcctcaagc tgaacttaaa
    16381 ttccctgaac aggaagatga ctcagatgac gaagatgttc aggtcgattt ttcagccaaa
    16441 gaagcccttg aatacaaact tccaagctta caactctttg caccagataa accaaaagat
    16501 cagtctaaag agaagaaaat tgtcagagaa aatatcaaaa tcttagaagc aacctttgct
    16561 agctttggta ttaaggtaac agttgaacgg gccgaaattg ggccatcagt gaccaagtat
    16621 gaagtcaagc cggctgttgg tgtaagggtc aaccgcattt ccaatctatc agatgacctc
    16681 gctctagcct tggctgccaa agatgtccgg attgaagcac caatccctgg gaaatcccta
    16741 atcggaattg aagtgcccaa ctccgatatt gccactgtat ctttccgaga actatgggaa
    16801 caatcgcaaa cgaaagcaga aaatttcttg gaaattcctt tagggaaggc tgttaatgga
    16861 accgcaagag cttttgacct ttctaaaatg ccccacttgc tagttgcagg ttcaacgggt
    16921 tcagggaagt cagtagcagt taacggcatt attgctagca ttctcatgaa ggcgagacca
    16981 gatcaagtta aatttatgat ggtcgatccc aagatggttg agttatctgt ttacaatgat
    17041 attccccacc tcttgattcc agtcgtgacc aatccacgta aagccagcaa ggctctgcaa
    17101 aaggttgtgg atgaaatgga aaaccgttat gaactctttg ccaaggtggg agttcggaat
    17161 attgcaggtt ttaatgccaa ggtagaagag ttcaattccc agtctgagta caagcaaatt
    17221 ccgctaccat tcattgtcgt gattgtggat gagttggctg acctcatgat ggtggccagc
    17281 aaggaagtgg aagatgctat catccgtctt gggcagaagg cgcgtgctgc aggtatccac
    17341 atgattcttg caactcagcg tccatctgtt gatgtcatct ctggtttgat taaggccaat
    17401 gttccatctc gtgtagcatt tgcggtttca tcaggaacag actcccgtac gattttggat
    17461 gaaaatggag cagaaaaact tcttggtcga ggagacatgc tctttaaacc gattgatgaa
    17521 aatcatccag ttcgtctcca aggctccttt atctcggatg acgatgttga gcgcattgtg
    17581 aacttcatca aggctcaggc agatgcagac tacgatgaga gttttgatcc aggtgaggtt
    17641 tctgaaaatg aaggagaatt ttcggatgga gatgctggtg gtgatccgct ttttgaagaa
    17701 gctaagtctt tggttatcga aacacagaaa gccagtgcgt ctatgattca gcgtcgttta
    17761 tcagttggat ttaaccgtgc gacccgtctc atggaagaac tggagatagc aggtgtcatc
    17821 ggtccagctg aaggtaccaa acctcgaaaa gtgttacaac aataaaaaaa tagcttcttt
    17881 ccgagtttgg agggaagcta ttttagtggc tattgattgc ttttattttc tgaagttggc
    17941 gcattggact gtttttcgtt ttcagtagca ggtttacttg aagcaggagt agaagagtcc
    18001 tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt tggtgtttcc
    18061 tcttgctgtg ttttttcttg actagtgtta gtctctttag ttggactggt gttttcctta
    18121 ggggattcct tttggatttc tttgacaatg gttgtcgtct ggcttgtcgt aggttctttt
    18181 ttaatatttt tgttattatc caaggcgttc atgatcgtga tacccgcggt aatcaagcca
    18241 aggatactag cgattgtagc aacggttttt tgaaagactg taaagccttt tttgatgtgt
    18301 tctgtttttg gttttgaagt tctacgatag ttagacatac attctctcct ttgattatga
    18361 tttattatac tctgtttctt taaaaaaatc ttaaaaaaag agaaattgcc ctttcttgtc
    18421 gcaggctccg tttcatgata caatagaagg agtgatttta gaaagcgtga gaaacatgat
    18481 ttactttgat aattcggcga cgaccaggcc ctatccagaa gcccttgaaa cctatatgca
    18541 ggtggcttca aaaattttag gaaatccatc tagtctccat cgtttgggag accaggcaac
    18601 acgaatttta gatgcttccc gtcaacagat tgcagattta atcggtaaga aaagtgatga
    18661 aatcttcttt acatctggtg ggacagaagg ggataactgg atcatcaagg gagtagcatt
    18721 tgaaaaagcc cagtttggca agcacatcat cgtatcagcc attgaacatc cagcagttaa
    18781 ggaatcagcc ctctggttga aagctcaagg ttttgaagtg gattttgctc cagttgataa
    18841 caaaggattt gtggatgttg aggcgctaga agatttgata agacctgata cgaccctcgt
    18901 ttccatcatg gcagttaaca atgaaattgg ctctgttcag cccattgagg ctatttcaaa
    18961 actattggca gacaagccaa ctatttcctt ccacgttgat gcggttcagg cgcttgccaa
    19021 gattccgact gaaaagtatc tgacagaacg ggtggattgc gcgaccttct cgagtcataa
    19081 atttcatggt gtccgtggtg ttggctttgt ctatatcaaa tctggcaaga agattactcc
    19141 tcttttaaca ggtggtggtc aggaacgtga ttaccgttcg acaactgaaa atgtggcagg
    19201 aattgcagcg acagccaagg ccctccgttt atctatggaa aagctagata tctttaggag
    19261 caagactggg cagatgaagg cagtgattcg tcaagcactt ctggactatc cggatatatt
    19321 tgtcttttca gatgaggaag acttcgcccc tcatattctg acttttggaa tcaagggtgt
    19381 tcgtggtgag gtcattgttc acgcctttga agactatgat attttcatct caacgacctc
    19441 ggcttgttcg tccaaggctg ggaaaccagc cggaaccctg attgctatgg gagtggacaa
    19501 ggataaggct cagtcagctg tgcgtcttag tctagacctt gaaaatgata tgagtcaggt
    19561 cgagcagttc ttgaccaagc taaaattaat ttacaatcaa actagaaaag taagatagga
    19621 gcattcatgc agtattcaga aattatgatt cgctacggtg agctgtcaac caagggcaaa
    19681 aatcgtatgc gtttcatcaa taaacttcgc aataatattt cagacgtttt gtctatctat
    19741 ccccaagtta aggtaacagc agatcgcgac cgtgcccacg cttacctcaa tggagcagat
    19801 tacacagcag tagcagaatc gctcaaacaa gtatttggaa ttcaaaactt ttcccctgtt
    19861 tataaggttg aaaaatctgt agaagttctg aagtctgctg tccaagagat tatgcaggac
    19921 atctacaagg aaggcatgac ctttaaaatc tctagcaagc gtagcgacca cacctttgaa
    19981 ttggacagtc gtgaactcaa ccaaacgctt ggaggggctg tattcgaagc cattccaaac
    20041 gtacaagctc aaatgaaaag tcctgacatc aatcttcagg tggagatacg tgaagaagca
    20101 gcctatcttt cttatgaaac cgttcgaggg gcaggtggat taccagtggg aacttctggt
    20161 aagggcatgc tcatgttgtc agggggaatc gattcccctg tagctggcta tctagcgctt
    20221 aaacgagggg tagatataga ggcagttcac tttgccagcc caccttacac gagtcctggt
    20281 gctcttaaaa aagcccaaga tttgacccgt aaattaacca aatttggggg aaatatccag
    20341 tttatcgaag ttccttttac agagattcaa gaggaaatca aagccaaagc gccagaagcc
    20401 taccttatga ccttgacgcg tcgttttatg atgcgtatta ctgaccgtat tcgtgaggta
    20461 cgaaatggtt tagttatcat caatggggaa agtctaggtc aagtagccag ccaaaccctt
    20521 gaaagtatga aggctatcaa tgctgttacc aacactccca tcattcgtcc tgtggttacc
    20581 atggacaagt tggaaatcat tgacatcgcc caggaaatcg atacctttga catttcaatc
    20641 caaccgtttg aagactgttg taccattttt gcaccagatc gtccaaaaac aaatcctaaa
    20701 attaagaatg cggagcagta cgaagcgcgt atggatgttg aaggcttggt tgagcgagca
    20761 gtggctggaa tcatgattac tgaaatcaca cctcaagccg aaaaagatga agttgatgac
    20821 ttgattgaca atctgctcta attcagaaaa tccaaaagaa tagcgaaaat cagtaaaaaa
    20881 agttagtttt ttctctaaaa acaggtaaaa aactaacttt ttttattttt atgatataat
    20941 gatataaaat tttgaatata gagagttttc tgacaatgaa tcaatcctac ttttatctaa
    21001 aaatgaaaga acacaaactc aaggttcctt atacaggtaa ggagcgccgt gtacgtattc
    21061 ttcttcctaa agattatgag aaagatacag accgttccta tcctgttgta tactttcatg
    21121 acgggcaaaa tgtttttaat agcaaagagt ctttcattgg acattcatgg aagattatcc
    21181 cagctatcaa acgaaatccg gatatcagtc gcatgattgt cgttgctatt gacaatgatg
    21241 gtatggggcg gatgaatgag tatgcggctt ggaagttcca agaatctcct atcccagggc
    21301 agcagtttgg tggtaagggt gtggagtatg ctgagtttgt catggaggtg gtcaagcctt
    21361 ttatcgatga gacctatcgt acaaaagcag actgccagca tacggctatg attggttcct
    21421 cactaggagg caatattacc cagtttatcg gtttggaata ccaagacaaa attggttgct
    21481 tgggcgtttt ttcatctgca aactggctcc accaaccgct atatcgagtg ccagaaacta
    21541 tcgcctgacc aacgcatctt catctatgta ggaacagaag aagcagatga tacagacaag
    21601 accttgatgg atggcaatat caaacaagcc tatatcgact cgtcgctttg ctattaccat
    21661 gatttgatag cagggggagt acatctggat aatcttgtgc taaaagttca gtctggtgcc
    21721 atccatagtg aaatcccttg gtcagaaaat ctaccagatt gtctgagatt ttttgcagaa
    21781 aaatggtaag ttaagaaagg aaaaaacgaa atgcatattg aacatcttag ccactggagt
    21841 ggtcatccta accgtgaaat gtaccttaac cgttatggac atggtgggat tccagttgtg
    21901 gtctttgctt catcaggtgg tagtcacaac gaatactatg attttggcat gattgatgcc
    21961 tgtgcttcct ttatcgagga aggccgtgtc cagttcttta ccctatctag tgtggatagt
    22021 gagagctggt tggctacttg gaaaaatgct catgaccaag cggaaatgca ccgtgcctac
    22081 gaacgttatg tgattgagga ggccattctt ttatcaagca caagacaggt tggtttgatg
    22141 gcatgatgac gacaggttgc tctatgggag cctatcatgc actcaatttc ttcctccagc
    22201 atccagatgt ctttaccaaa gtgattgctc tcagtggtgt ttacgacgca cgtttctttg
    22261 tcggtgatta ctacaacgat gatgctattt accaaaactc gccagtagat tatatttgga
    22321 actaaaacga cggctggttt attgaccgtt accgtcaggc agagattgtg ctgtgtacgg
    22381 ggcttggagc ctgggaacaa gatggtttgc catcctttta caagctcaaa gaagcctttg
    22441 acaagaaaca aattccagcc tggtttgctg aatggggaca tgatgtcgcc catgactggg
    22501 aatggtggcg taaacaaatg ccttatttcc tcggtaatct ctatttataa aaggagttac
    22561 ctatgaatta ccttgttatt tctccctact atccacaaaa ctttcaacag tttaccatcg
    22621 aactagctaa taaaggcatc acagtcttgg gaattggtca agagtcttac gagcaattgg
    22681 atgagccctt gcgcaatagc ttgaccgagt attttcgtgt tgataatctt gagaacatag
    22741 atgaagtcaa acgtgcagtt gcttttctct tttataaaca tggtccaatt ggccgcatcg
    22801 agtctcacaa tgaatactgg cttgagctag acgcaacact cagagaacaa ttcaatgttt
    22861 ttggtgccaa accagaggat ctcaaaaaga cgaaatataa gtctgaaatg aagaaacttt
    22921 tcaaaaaagc aggtgttcct gtggtacctg gagctgttat caagacggaa gcagatgttg
    22981 atcaagcagt gaaagaaatc ggtcttccaa tgattgccaa acctgataat gaagtgggag
    23041 cagccgcaac ctttaaactt gagacagaag acgatatcaa tcacttcaag caagaatggg
    23101 accattcaac cctttatttc tttgaaaaat ttgtcacttc cagcgaaatc tgtacctttg
    23161 acgggctcgt ggacaaggat ggaaagattg tcttctcaac aacctttgac tacgcctata
    23221 caccgcttga cctcatgatt tataagatgg acaattctta ttatgtgctc aaggatatgg
    23281 atcctaaact gcgcaagtat ggggaagcaa ttgtcaaaga atttggtatg aaagaacggt
    23341 ttttccatat tgagttcttc cgtgaggggg acgattatat taccattgag tacaataacc
    23401 gccctgcagg tggtttcacc attgatgttt ataactttgc tcattccttg gacctctatc
    23461 gtggatatgc agccattgtc gcaggagaag agttcccagc gtcagacttt gaacctcagt
    23521 attgtttggc tacatcacgt cgtgcaaatg ctcactatgt ctattctgag gagaacttac
    23581 ttgccaaata tagccagcag ttcaaggtta aaaaaatcat gccagaggct tttgcggaac
    23641 ttcaaggaga ttacttttat atgctgacaa ctccgagtcg acaagaaatg gatcagatga
    23701 ttgctgattt cggacaacgt caagaataag aactatcgga ttaaggaaat tcactccctt
    23761 aatccttttg ttttgtctgg taaaaaataa gagcatccta acaaggtagc tatcataaaa
    23821 cttgttcgat aactatttga agcaggatta ggttgctcaa aacactgttt tgaggttgtg
    23881 gatagaactg acagagtcag tatcatatac ctacggcaag gtgaagctga cgtggtttga
    23941 agagattttc gaagagtata aaatattcag gtgacgcata gatatagtta attgaagctt
    24001 tgtttgaaat ctgataaaat aatgatatta ctaagtttta aaaactaaag aaaagggaag
    24061 atatgattac aggcgaatta aaaaataaaa tcgatcagct gtgggaaatt ctttggacag
    24121 aaggaaacgc aaatccttta acaaatattg aacagttgac ttatctctta tttatgaaag
    24181 atttggatag tgtcgagctt ggacgtgaaa gtaatgctga atttctaggg attccttatg
    24241 agggagtttt tccaaaagat aaacctgaat accgttggtc aacttttaaa aatataggag
    24301 atgctcagga agtttatcgt ttaatgactc aggagatttt tccgtttatt aaaaatctca
    24361 agggggatac agatgataca gccttttcac gatatatgcg agaagctatt tttcaaataa
    24421 ataaacctgc tacgcttcaa aaggcaattt ctatcttaga tgtttttcca actaggggat
    24481 tagatgtaga ttttgataat gacaaacaaa gtattactga tatcggagat atctatgaat
    24541 atctgttatc aaaattgtcg accgcaggta aaaatggaca gttccgtaca cctcgtcaca
    24601 tcatcgatat gatggttgag ttgatgcaac cgactatcaa agatatcatc tcagatcccg
    24661 ctatgggttc tgctggcttc ttagtatctg ctagccgtta cttaaagcgt aagaaagatg
    24721 aatgggaaac caatacagat aatatcaatc attttcataa tcagatgttt catggaaatg
    24781 atacggatac gactatgttg agacttgggg cgatgaacat gatgctacat ggagtagaaa
    24841 atccacaaat cagttacctt gactcgctgt ctcaagataa tgaagaagct gataaatata
    24901 ctttggtttt agcaaatcct ccttttaagg gctcacttga ctacaattca acctctaatg
    24961 accttcttgc aaccgtaaaa accaaaaaaa cagaattact ctttctttct cttttcttgc
    25021 gaactttaaa accaggtgga cgagcagcag ttatcgtacc tgatggtgtc ctttttggtt
    25081 cgtctaaagc tcataaagga attcgtcagg aaattgtaga gaatcataag cttgatgctg
    25141 taatctcaat gcctagtggt gtgttcaagc cttatgctgg agtttcaact gccattctca
    25201 tctttacaaa aactggtaat ggtggtactg acaaagtctg gttttacgat atgaaagcgg
    25261 atggtttaag tttggatgat aagcgacaac cgattagaga caatgatatt ccagatatta
    25321 tcgaacgctt tcatcatctt gaaaaagaag cagaacgtca gagaacggat caatctttct
    25381 ttgttccagt tgctgagata aaggaaaatg attatgattt gtctatcaat aaatataaag
    25441 agattgagta tgaaaaagtt gagtatgaac caacagaagt catattaaag aaaatcaatg
    25501 atttagaaaa agaaattcaa gctggcttgg ctgaattgga aaaattactc aagtagggag
    25561 gtggctgtat gaaaaaagtg aagttggggg aagtcttatc tctaaaaaaa ggcaagaaag
    25621 ccactgtact tgctgaacaa acaactctaa gccaacgtta tattcaaata gatgatttaa
    25681 gaaataataa taatttaaaa ttcactgaaa gtttaaatat gactgaagca cttccagatg
    25741 atattctaat agcatgggat ggtgctaatg caggaacagt tggttatgga ttatcgggag
    25801 ctgttggtag tacaattacg gtcttaaaaa agaatgagcg atacaaagaa aaaattatat
    25861 cagattactt gggagtcttt ttggaaagta aatcgcagta tttacgagat cattcaacag
    25921 gtgcaactat tcctcattta aacaagaata tattacttga tttacaatta gaattgctag
    25981 gtatcgaaga acaagagaac attatctgta ttcttaatac gattaaaagg cttattacta
    26041 aaagaaaatt tcagttagat gaactaaact tgctcgtcaa atcccgattt aacgagatgt
    26101 ttggggaaaa taaaatattt gaaagcattg ataacttatt tgatattata gatggtgata
    26161 ggggcaaaaa ttatcctaaa tcagatgagt tgtttagtga ggagtactgt ttatttttaa
    26221 atacaaagaa tgttactaaa aacggatttt cattcgatac aaagcaattt atcactaaaa
    26281 caaaggataa attacttcga aaaggcaaac ttgagcgtta tgatatagtc ttgacaacaa
    26341 gaggtactgt tggaaatgta gcgtactacg atgaattaat aaaatataaa catttacgta
    26401 taaattcagg tatggtaata ttacgtccca agacaccaaa tcacaatttg cttgtgagat
    26461 agctataaaa gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt
    26521 taaagtgaga aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct
    26581 ttttcaaaac cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc
    26641 tttatggcgc gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat
    26701 ttagaagctc cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat
    26761 atcgtagatt ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct
    26821 gctcatggtg gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag
    26881 tttgttaatt ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag
    26941 aagtgcttac cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag
    27001 ttacaagaca gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta
    27061 gaagttcaag agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct
    27121 ttccatattg atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc
    27181 cgtttagcag gatggatatt tgaagaaaac tgtcgtgttg agatagccgt tgatggtctc
    27241 aagcacggtt caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt
    27301 ttagcgattg tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc
    27361 aaagaatatg ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca
    27421 aatgggttga agcactatat acttgatggt ccgaaccgcc gccagattgc aggcttttac
    27481 tctcaagaag aattgcaatt agtgatggat agacgtcatc ttcaaaaacc gcttgaggat
    27541 atttctagta aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca
    27601 agcgtttgtg aagctttctc taatcatcgt agacaggcac ttttggttat ggcaactggg
    27661 gctgggaaaa ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta
    27721 aaaaacgttc tcttcttagc cgatagaact tccttggtta agcaagcata tgattcgttt
    27781 agaaaattac tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa
    27841 tcaagtcgca tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa
    27901 gaagtaaatc aacgcccttt cactgttggg cattttgacc ttatcataat tgacgaatct
    27961 caccgttcta tttatcagaa atacaagtcc atttttgatt attttgatgc aagaattgta
    28021 ggcttaacag ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg
    28081 ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag acggatattt
    28141 agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc tacattatga
    28201 tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg atagctgtga
    28261 aaaagatatt gatgggagtg tatttaattc ctttattttc aataaaagta cagtagaaat
    28321 tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg aaattggtaa
    28381 aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta tttttaacaa
    28441 ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta ttaagcatta
    28501 tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg cgatttctgt
    28561 cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct tcttcaagaa
    28621 agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc tatgtaaaga
    28681 tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg gggacaattt
    28741 tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt cgctgactca
    28801 gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc aataccaaga
    28861 agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag gtcgtataga
    28921 gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt atagctatag
    28981 gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc aaaaaaatct
    29041 ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat ttgatttgtg
    29101 gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc atatttccca
    29161 agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg tttttgagca
    29221 ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta acttgtctga
    29281 tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata aaacagaccg
    29341 taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg agaccacagc
    29401 atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt atttgaaaac
    29461 tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga catctgatga
    29521 tatgcttgca cttgaaaaat tgctttggga aaaattaggt agtaaagcag actaccaaag
    29581 tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct tagatagaga
    29641 gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg ccaggcagat
    29701 ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag agacgaaagt
    29761 gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc aacaccaact
    29821 accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag ctggagaagc
    29881 ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa agagtagaaa
    29941 tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct agaatacagt
    30001 atcagttgtt aagtggttga taaatttcaa agtagatact tgtaccacga tgtttgttga
    30061 tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa aaagccgagc
    30121 aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag agcaaactag
    30181 gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga ctgacgaagt
    30241 cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta accataccta
    30301 cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat cttcctagga
    30361 taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt tttctgatgt
    30421 taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt tattattctt
    30481 caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga gcagtatctg
    30541 catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata gcgtcaggga
    30601 agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg gtttttagta
    30661 ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag agttcgagac
    30721 gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta tcttcttcgc
    30781 ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg gttacttgaa
    30841 tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg ttttttgtga
    30901 taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg taactccttt
    30961 tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta gtctgtattg
    31021 tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt gtctccttct
    31081 tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc atctgcagta
    31141 atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc ttttgtcacg
    31201 actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat gtgatagcga
    31261 ccgttgtcaa tggttctagc acttaaaata gctggataag gttgtaggta tttcttttgc
    31321 ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt gatacgaaga
    31381 ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt aatagtaatc
    31441 tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt actatagcgc
    31501 tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc aagtgagaag
    31561 gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg tggagctgta
    31621 ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag taatttcttg
    31681 gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt catgtaaaca
    31741 tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc atggaacatc
    31801 tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa gacaacctct
    31861 gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg attgtagtcc
    31921 ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg agcttcattg
    31981 ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc aagggagtca
    32041 aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg gtagtagttg
    32101 taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac tcctgtagtc
    32161 gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac ttttccgttt
    32221 gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcatg gcaacggccg
    32281 ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc attagtcatg
    32341 aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa gcctctcgga
    32401 aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc ctcagcctct
    32461 gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt ctctagctca
    32521 atcttgcgag gaagcttaac cttaagctcg ccctccatct tgtagagagc cttgtcacta
    32581 gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg gatttttcca
    32641 tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt ttggtcagta
    32701 tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga aaaagtagcc
    32761 aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc atcactaaca
    32821 agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg atagagattt
    32881 tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac gtcactatct
    32941 tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata aaaaatatct
    33001 gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt atcagctgct
    33061 aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg taaaaaggtt
    33121 tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt ttttagctca
    33181 gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg catagaacct
    33241 ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaa
//
LOCUS       DAVMBH010000022        32059 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVMBH010000022 DAVMBH010000000
VERSION     DAVMBH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.022"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            63..926
                     /locus_tag="VYP30_001121"
     CDS             63..926
                     /locus_tag="VYP30_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808128.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYENLEYIYRIEIERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1309..1929
                     /locus_tag="VYP30_001122"
     CDS             1309..1929
                     /locus_tag="VYP30_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808129.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2015..2458
                     /gene="tsaE"
                     /locus_tag="VYP30_001123"
     CDS             2015..2458
                     /gene="tsaE"
                     /locus_tag="VYP30_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1808130.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2448..2966
                     /locus_tag="VYP30_001124"
     CDS             2448..2966
                     /locus_tag="VYP30_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808131.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTGE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQVSGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            2974..3990
                     /locus_tag="VYP30_001125"
     CDS             2974..3990
                     /locus_tag="VYP30_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1808132.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4075..5331
                     /locus_tag="VYP30_001126"
     CDS             4075..5331
                     /locus_tag="VYP30_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1808133.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRPLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQVLDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5386..6552
                     /gene="recA"
                     /locus_tag="VYP30_001127"
     CDS             5386..6552
                     /gene="recA"
                     /locus_tag="VYP30_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1808134.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEASEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            6858..8228
                     /locus_tag="VYP30_001128"
     CDS             6858..8228
                     /locus_tag="VYP30_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1808135.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQSLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8604..9560
                     /gene="lytA"
                     /locus_tag="VYP30_001129"
     CDS             8604..9560
                     /gene="lytA"
                     /locus_tag="VYP30_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1808136.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9919..10092
                     /locus_tag="VYP30_001130"
     CDS             9919..10092
                     /locus_tag="VYP30_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808137.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            10079..10285
                     /locus_tag="VYP30_001131"
     CDS             10079..10285
                     /locus_tag="VYP30_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808138.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            10331..10690
                     /locus_tag="VYP30_001132"
     CDS             10331..10690
                     /locus_tag="VYP30_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808139.1"
                     /translation="MKKSSVSLILIGEGDETERKADQLASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLG"
     gene            10819..11244
                     /locus_tag="VYP30_001133"
     CDS             10819..11244
                     /locus_tag="VYP30_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808140.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEMYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            11652..12647
                     /locus_tag="VYP30_001134"
     CDS             11652..12647
                     /locus_tag="VYP30_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808141.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLLFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPFSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            12637..13188
                     /locus_tag="VYP30_001135"
     CDS             12637..13188
                     /locus_tag="VYP30_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808142.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLNEDYYNILVHEKETIQGYLVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLRLAS"
     gene            13247..13507
                     /locus_tag="VYP30_001136"
     CDS             13247..13507
                     /locus_tag="VYP30_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808143.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(14272..14671)
                     /locus_tag="VYP30_001137"
                     /pseudo
     CDS             complement(14272..14671)
                     /locus_tag="VYP30_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14796..15254
                     /locus_tag="VYP30_001138"
     CDS             14796..15254
                     /locus_tag="VYP30_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1808144.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15267..15875
                     /locus_tag="VYP30_001139"
     CDS             15267..15875
                     /locus_tag="VYP30_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808145.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            15946..16278
                     /locus_tag="VYP30_001140"
     CDS             15946..16278
                     /locus_tag="VYP30_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808146.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            16289..17704
                     /gene="ply"
                     /locus_tag="VYP30_001141"
     CDS             16289..17704
                     /gene="ply"
                     /locus_tag="VYP30_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1808147.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            18585..19301
                     /locus_tag="VYP30_001142"
     CDS             18585..19301
                     /locus_tag="VYP30_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1808148.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            19425..19895
                     /locus_tag="VYP30_001143"
     CDS             19425..19895
                     /locus_tag="VYP30_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1808149.1"
                     /translation="MDKPMLVFKRFGHQIYLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            19911..20732
                     /locus_tag="VYP30_001144"
     CDS             19911..20732
                     /locus_tag="VYP30_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808150.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQPA
                     SMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVAVIINVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLGVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            20739..21770
                     /locus_tag="VYP30_001145"
     CDS             20739..21770
                     /locus_tag="VYP30_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1808151.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVRQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            21836..22198
                     /locus_tag="VYP30_001146"
     CDS             21836..22198
                     /locus_tag="VYP30_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEV1808152.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDSLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            22195..22698
                     /locus_tag="VYP30_001147"
     CDS             22195..22698
                     /locus_tag="VYP30_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1808153.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSAAIISMACLHASLPIGLVCLNFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLL"
     gene            22812..23258
                     /locus_tag="VYP30_001148"
     CDS             22812..23258
                     /locus_tag="VYP30_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808154.1"
                     /translation="MKLRIEIDGNLEETEIVIKAAALTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            23263..23937
                     /locus_tag="VYP30_001149"
     CDS             23263..23937
                     /locus_tag="VYP30_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808155.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            24098..24289
                     /locus_tag="VYP30_001150"
     CDS             24098..24289
                     /locus_tag="VYP30_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1808156.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            24626..24925
                     /locus_tag="VYP30_001151"
     CDS             24626..24925
                     /locus_tag="VYP30_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1808157.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            24922..25239
                     /locus_tag="VYP30_001152"
     CDS             24922..25239
                     /locus_tag="VYP30_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1808158.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            25255..25881
                     /locus_tag="VYP30_001153"
     CDS             25255..25881
                     /locus_tag="VYP30_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1808159.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            25914..26675
                     /locus_tag="VYP30_001154"
     CDS             25914..26675
                     /locus_tag="VYP30_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1808160.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            26753..27148
                     /locus_tag="VYP30_001155"
     CDS             26753..27148
                     /locus_tag="VYP30_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1808161.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            27304..27588
                     /gene="groES"
                     /locus_tag="VYP30_001156"
     CDS             27304..27588
                     /gene="groES"
                     /locus_tag="VYP30_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1808162.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            27604..29226
                     /gene="groL"
                     /locus_tag="VYP30_001157"
     CDS             27604..29226
                     /gene="groL"
                     /locus_tag="VYP30_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1808163.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            29364..30119
                     /locus_tag="VYP30_001158"
                     /pseudo
     CDS             29364..30119
                     /locus_tag="VYP30_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            30565..31338
                     /locus_tag="VYP30_001159"
     CDS             30565..31338
                     /locus_tag="VYP30_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1808164.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            31351..31689
                     /locus_tag="VYP30_001160"
     CDS             31351..31689
                     /locus_tag="VYP30_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808165.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            31722..32059
                     /locus_tag="VYP30_001161"
                     /pseudo
     CDS             31722..32059
                     /locus_tag="VYP30_001161"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT         9967 a         5373 c         7052 g         9667 t
ORIGIN      
        1 tgctattttg aactaaaaat tttataatga aattaagcaa acaggaaggt ttattatctt
       61 taatgaatac actcgcagag aaattcagat tgaaaagaaa agagttgaga ctctcccagc
      121 aaactcttgc agaaggaatt tgtgaacaaa gccagattag taaaattgag agagggcatt
      181 tcattccctc cgcagacctt ttgttcaaac tctcacaacg acttgaagtg ccattagatt
      241 atttttttaa tgaacaaatt gaaattaaat ctaacctctc taatttcaag caattatctg
      301 ctcgcctatt agatgataga aattatgaaa atttggaata tatttataga atagagattg
      361 aacgaagtac ttttctaaca ctagaagacc gaacttacct tgaatggatt aaatctataa
      421 ttgacttcta tcaatatgac agtaagtgtg aagcaatttc ttcattggaa aatatattat
      481 taaaagtctc ttcaaatact ctgatttatt taaaggcgtt gaatactcta tctaatttct
      541 attccttagt gggtcgtgaa caagaatatg aggcaaacta ctctcattta atagagttgt
      601 atcagacaaa aaatttggac catcaagagt ttttatttgg ctacatcaga gttcgttaca
      661 actacgctca ctacctagta tcaaaggaaa aatataatga agccatccaa gaagctcttg
      721 aaacgattga actctgtaaa caaagacaga caagctacca attggctcct ctacttattc
      781 ttgtaggaaa tgctggagcc aaatttctag acagagaaca agtcaaaaat tattatatag
      841 aagcaagaga gttatgtaag atttataaca atcctttaat gttgatgaag atagaaaatt
      901 atttgaagga actagatact gtttagttaa tcttgacatt atagtttttc tgaaacgtta
      961 aataacctgt aaggctgata gttagattaa tactatcagc cttataatta tgtgactctg
     1021 agtccgtctc gctccgtgag gtgcgagaca aaacaaccac ccgtttgacg gattttcatg
     1081 atttcaaatt tatattcttc gaaaatctct tcaaatcacg tcagctctat ctgcaatctc
     1141 aaaacagtgt tttgagcaac ctgtggctag ctacctagtt tgatctttga ttttcattga
     1201 gtattagtct ctagtgtttg tttagcgtct taaagagaca tttgagaaga ttagaaacag
     1261 ttctctcttt tctcctagta taatgattgg taggaaggga gagagaagat gaaatcaatg
     1321 agaatcttat ttttgttagc tttaattcaa atcagtttga gtagctgttt cttatggaag
     1381 gaatgcatct tgtcctttaa acaaagtaca gcttttttca tcggaagcat ggttttcgtt
     1441 tcaggaatct gtgctggagt aaattatctt tatacccgta agcaagaagt ccatagtgtc
     1501 ctagccagta agaagtcggt gaagcttttt tacagtatgt tactcttaat taatttgtta
     1561 ggagctgttc ttgttttgtc agataacttg ttcatcaaaa atacgctgca gcaagaatta
     1621 gttgactttt tattgccatc cttctttttc ctatttgggc tagatttgct gattttttta
     1681 cccttgaaaa aatacgtgcg cgattttctt gctatgctag acagaaaaaa gacagtgttg
     1741 gtgactattt tagcaacact tcttttctta agaaatccaa tgaccattgt ctcacttctg
     1801 atttatattg gactgggctt gttttttgca gcctatcttg tcccaaattc ggttaagaag
     1861 gaagtttcct tttatggtca tattttccga gatcttgtat tggtcattgt tacgctcatt
     1921 ttcttttaga gaaagcctgt tttttatgga tgttatgatg ataagtttag taggaaaata
     1981 gacacaaaag aaaagttttt ggtataataa gagtatgtac ataaaaaatg aagaagagtt
     2041 gcaagcctta ggggagcgtt tgggccatct attagcaaag aatgatgttt taatcttaat
     2101 tggagaactg ggtgcaggta aaacgacctt tactaaagga cttgcaaaag gattacagat
     2161 ttctcaaatg attaaaagtc ctacctatac tatcgtgaga gagtatgaag gtcgacttcc
     2221 actttatcac ctagatgttt atcgtattga aggagatgct gattctatcg acttggatga
     2281 gtttatcttt ggtggcggcg tgactgttat tgagtgggga aatctcttag gagatgcctt
     2341 gccagatgct tatttagaat tggaaattct aaaagaagca gatggacgcc gtttaaattt
     2401 tcaggcaaag ggtttgcgtg ctgagaaatt gttagaggag cttcaatatg gagtatgaat
     2461 tgctcattag ggaagcagag cccaaagatg cagctgaatt agtggccttt ttaaatcgtg
     2521 tgagtttgga gacagacttt accagcctag acggagatgg tattctcttg actggtgagg
     2581 agatggaaat attcctcaac aagcaagcta gttcggacaa tcagataacc ttacttgcat
     2641 tcttaaatgg caaaattgct ggtattgtaa atattacagc tgaccagcgt aagagagtcc
     2701 gtcatattgg agatctcttc attgtgattg gaaaaagata ttggaataat ggcttgggaa
     2761 gtttgttgct agaagaagcg atagagtggg cacaagtaag tggcattctg cgtcgtctcc
     2821 aactgactgt ccaaactcgt aatcaagcag cagtccatct ttatcaaaag catggctttg
     2881 tcattgaagg tagccaagag cgtggggcat atatagaaga agggaaattt atcgatgttt
     2941 acttgatggg taaactgata ggttagtaga aatatggtta aaaaaattat tggaatggtg
     3001 ctagctttac tttctgtaac tgtagtagga gtaggtgttt ttgcttatac tatttatcaa
     3061 caagggacag aaaccttagc taaaacctat aaaaaaatcg gcgaagaaac caaggttatt
     3121 gaagcgactg aacctctaac cattctgtta atgggagtgg acaccggaaa tgttgaacga
     3181 actgaaactt gggtcggtag aagtgatagc atgatcttga tgacagtgaa tcctaaaacg
     3241 aaaaaaacaa caatgatgag tttagagcgg gatattctga cgcgcattga atcagggaat
     3301 ggtcaggctc atgaagcgaa actgaactca gcatatgcag atggtggagc agagcttgct
     3361 atagaaacca ttcaaaaaat gatgaatatc catattgatc gctatgtgat ggtcaatatg
     3421 agagggttgc aaaaactagt ggatgcagta ggaggtatta cagtcaataa tatcctaggt
     3481 ttcccaattt ctatcagtga ccaagaagaa tttaatacta tttctatcgg tgttggggag
     3541 caacatattg ggggagaaga agccctagtc tatgcacgaa tgcgttacca agatcctgag
     3601 ggggattatg gtcgtcaaaa acgtcaacgt gaagttattc aaaaagtcat ggaaaaagct
     3661 ctcagtttaa atagcgttgg tcattatcaa gagattctaa aagctttgag tgacaatatg
     3721 cagaccaata ttgatttgtc tgcaaaaagt atccctaact tgctaggcta taaagattca
     3781 tttaaaacca ttgaaactca gcagttgcag ggtgaaggag agatacttca aggtgtttct
     3841 taccagattg tttcgagagc acatatgttg gaaatgcaaa atatactccg acgttctttg
     3901 ggacaagaag aagttactca gcttgaaacc aatgcggttt tatttgaaga tttatttggc
     3961 agagcacctg ttggtgatga agataattaa cttttgatac aaataaaaaa atcaatcgta
     4021 ggaaaattcc tgcgattttt tcaaaaaaat acgaatagat aggtaggagg aaacatgaaa
     4081 gcagaaatca ttgctgttgg aacagagatt ttgacaggac agattgtcaa caccaatgcc
     4141 cagtttttgt cggaaaaact agctgagatt ggggtagatg tatattttca gacggctgta
     4201 ggagacaatg aagttcgtcc cttgtctttg cttgagattg ccagtcaacg tagcagtctg
     4261 gtgattttga caggcggttt ggggccaact gaggacgacc taaccaaaca aaccctagct
     4321 aaatttttag ggaaagcatt agtctttgat cctcaggctc aggagaagtt ggatatcttt
     4381 tttgccctgc gaccagacta tgcccgaaca ccgaataacg aaagacaagc tcaaattgta
     4441 gaaggagcga ttccactgcc aaacgaaaca ggactggctg ttggaggaaa attagaagta
     4501 gacggagtga cctatgtcgt ccttccaggt ccgccaagtg aattgaaacc catggtctta
     4561 aaccaacttc tacccaagtt gatgacaggg agcaagctgt attcccgagt tcttcgtttc
     4621 tttgggattg gcgagagcca gctggttacg attttggctg atttaattga taatcagatc
     4681 gatcctacct tggcccctta tgccaagaca ggagaagtca ctctacgtct gtcaacaaag
     4741 gctagcagtc aagaagaggc gaatcaagtg ctggatatct tggaaaatca aatcttggac
     4801 tgccagactt tcgaaggaat ttctttacga gacttttgct atggttatgg ggaagaaact
     4861 agtttagcca gcattgtggt agaagaactg aaaaggcaag ggaaaaccat cgcggctgca
     4921 gagagtttga cggcaggtct tttccaagct accgtggcga atttttctgg agtttcaagt
     4981 atatttaagg gtggttttgt gacctatagc ttggaggaaa aatcaaggat gttggatatt
     5041 cctgccaaga atttggaaga acatggtgtg gtgtctgaat ttacagctca gaagatggct
     5101 gagcaggcac gaagcaagac ccagtctgat tttggaatta gtttgactgg agtggcagga
     5161 ccagatagcc tagaaggaca cccagttggg acagtcttca taggcttggc gcaagatcaa
     5221 ggaactgagg ttatcaaggt taatattgga ggcagaagcc gagcagatgt acgtcacatt
     5281 gcggttatgc atgcctttaa cctagttcgc aaggctttat taagtgacta acttttgata
     5341 taatagtaga taggtctgag gatcattaga atgtaggaga atagaatggc gaaaaaacca
     5401 aaaaaattag aagaaatttc aaaaaaattt ggggcagaac gtgaaaaggc cttgaatgac
     5461 gctcttaaat tgattgagaa agactttggt aaaggatcaa tcatgcgttt gggtgaacgt
     5521 gcggagcaaa aggtgcaagt gatgagctca ggttctttag ctcttgacat tgcccttggc
     5581 tcaggtggtt atcctaaggg acgtatcatc gaaatctatg gcccagagtc atctggtaag
     5641 acaacggttg cccttcatgc agttgcacaa gcgcaaaaag aaggtgggat tgctgccttt
     5701 atcgatgcgg aacatgccct tgatccagct tatgctgcgg cccttggtgt caatattgac
     5761 gaattgctct tgtctcaacc agactcagga gagcaaggtc ttgaaattgc gggaaaattg
     5821 attgactcag gtgcagttga tcttgtcgta gtcgactcag ttgctgccct tgttcctcgt
     5881 gcggaaattg atggagatat cggagatagc catgttggtt tgcaggctcg tatgatgagc
     5941 caggccatgc gtaaacttgg cgcctctatc aataaaacca aaacaattgc catttttatc
     6001 aaccaattgc gtgaaaaagt tggagtgatg tttggaaatc cagaaacaac accgggcgga
     6061 cgtgctttga aattctatgc ttcagtccgc ttggatgttc gtggtaatac acaaattaag
     6121 ggaactggtg accaaaaaga aaccaatgtc ggtaaagaaa ctaagattaa ggttgtaaaa
     6181 aataaggtag ctccaccgtt taaggaagcc gtagttgaaa ttatgtacgg agaaggaatt
     6241 tctaagactg gtgagctttt gaagattgca agcgatttgg atattatcaa aaaagcaggg
     6301 gcttggtatt cttacaaaga tgaaaaaatt gggcaaggtt ctgagaatgc taagaaatac
     6361 ttggcagagc acccagaaat ctttgatgaa attgataagc aagtccgttc taaatttggc
     6421 ttgattgatg gagaagaagc ttcagaacaa gatactgaaa acaaaaaaga tgagccaaag
     6481 aaagaagaag cagtgaatga agaagttacg cttgacttag gcgatgaact tgaaatcgaa
     6541 attgaagaat aagctgttaa agcagtggag aaatccgcta ctttttcgat ttttgattca
     6601 agtttttaga ttatatatag tagcttgaaa taagatatga acaactttat taggaaagtc
     6661 aaattaattt ctagaaatgt tttagcagct acagcgtact attccaaact caaccaatta
     6721 taatagatcg aaactagaat agtacacatc tacttctaaa acattgttaa aaatcgattt
     6781 gactgtcctt atttcattcc gctatatata gtttgctgtt tcttgtcgct cctctggaaa
     6841 gctgatataa tagctttatg aataaaaaac gaacagtgga cctgatacat ggtccgattc
     6901 ttccctcgct cttaagcttc gccttcccaa tcttgctatc aaatattttt caacagctct
     6961 ataacactgc tgatgtcttg attgttggac gatttcttgg tcaagaatcc ttggctgcag
     7021 taggagcgac gacagcgatt tttgacctga ttgtaggttt tacacttggt gttggcaatg
     7081 gcatggggat tgtcattgct cgttattatg gggctcggaa tttcactaaa atcaaggaag
     7141 cagtagcagc tacttggatt ttaggtgctc ttttgagcat tctagttatg ttgctgggct
     7201 ttcttggctt gtatcctctc ttgcaatact tagatactcc tgcagaaatt cttcctcaat
     7261 cttatcaata tatttctatg attgtgacct gtgtaggtgt cagctttgct tataatcttt
     7321 ttgcaggctt gttgcggtct attggtgaca gtctagcagc cctgggattt ctgattttct
     7381 ctgccttggt taatgtggtt ctggatctct attttattac gcaattgcat ctgggagttc
     7441 aatccgcagg acttgctacc attatttcgc aaggtttatc agcggttctc tgcttttatt
     7501 atattcgtaa aagtgtgcca gaactcttgc cacagtttaa acatttcaaa tgggacaaaa
     7561 gcttgtacgc ggatctcttg gagcaaggtt tggctatggg cttgatgagt tcaattgtat
     7621 ctatcggcag tgtgatttta cagttttctg ttaatacatt tggtgcagtg attattagtg
     7681 cccagacggc agctcgacgc attatgacct ttgcccttct tcctatgacc gctatttctg
     7741 catcaatgac gacctttgct tctcagagtc taggagctaa gcgacctgac cgcattgttc
     7801 aaggtcttcg aatcggcagt cgtttaagta tatcctgggc agtttttgtt tgtattttcc
     7861 tcttttttgc cagtccagcc ttggtttcct tcttggctag ttcgacagat ggttacttga
     7921 tagaaaatgg aagtctctat ctgcaaatca gttcagcctt ttatcccatt ttgagcctct
     7981 tgttgattta tcgcaattgc ttgcagggct tggggcagaa gatccttcct ctagtttcta
     8041 gctttattga actaatcgga aaaatcgttt ttgtggtttt gattattcct tgggcaggat
     8101 ataagggtgt tatcctttgt gaacctctta tctgggttgc catgacagtt caactgtact
     8161 tctcactatt ccgtcatccc ttgataaaag aaggaaaggc aattttggca accaaagtgc
     8221 aatcctagtt ggatttactg aataaaattc atttcctcta gtgaacatcg aaaaaacttg
     8281 tgttctcttc tttagtttgg tgttgaaaat agtttaacag acttttgact tcttttatat
     8341 gatataataa agtatagtat ttatgaaaag aacatataga gactgtaaaa atatactttt
     8401 gaaaagcttt ttagtctggg gtgttattgt agatagaatg cagaccttgt cagtcctatt
     8461 tacagtgtca aaatagtgcg ttttgaggtt ctatctacaa gcctaatcgt gactaagatt
     8521 gtcttctttg taaggtagaa ataaaggagt ttctggttct ggattgtaaa aaatgagttg
     8581 ttttaattga taaggagtag aatatggaaa ttaatgtgag taaattaaga acagatttgc
     8641 ctcaagtcgg cgtgcaacca tataggcaag tacacgcaca ctcaactggg aatccgcatt
     8701 caaccgtaca gaatgaagcg gactatcact ggcggaaaga cccagaatta ggttttttct
     8761 cgcacattgt tgggaacggt tgcatcatgc aggtaggacc tgttgataat ggtgcctggg
     8821 acgttggggg cggttggaat gctgagacct atgcagcggt tgaactgatt gaaagccatt
     8881 caaccaaaga agagttcatg acggactacc gcctttatat cgaactctta cgcaatctag
     8941 cagatgaagc aggtttgccg aaaacgcttg atacagggag tttagctgga attaaaacgc
     9001 acgagtattg cacgaataac caaccaaaca accactcaga ccacgttgac ccttatccat
     9061 atcttgctaa atggggcatt agccgtgagc agtttaagca tgatattgag aacggcttga
     9121 cgattgaaac aggctggcag aagaatgaca ctggctactg gtacgtacat tcagacggct
     9181 cttatccaaa agacaagttt gagaaaatca atggcacttg gtactacttt gacagttcag
     9241 gctatatgct tgcagaccgc tggaggaagc acacagacgg caactggtac tggttcgaca
     9301 actcaggcga aatggctaca ggctggaaga aaatcgctga taagtggtac tatttcaacg
     9361 aagaaggtgc catgaagaca ggctgggtca agtacaagga cacttggtac tacttagacg
     9421 ctaaagaagg cgccatggta tcaaatgcct ttatccagtc agcggacgga acaggctggt
     9481 actacctcaa accagacgga acactggcag acaagccaga attcacagta gagccagatg
     9541 gcttgattac agtaaaataa taatggaata tctttcaaat cagaacagcg catattatta
     9601 ggtcttgaaa aagcttaata gtatgcgttt tcttgtggag atatttcctt caatttttgt
     9661 tactatatta aacaaaaatc aaaaagcaaa ctagaaagtt atgctcaaat aaaatctaaa
     9721 tttgacaatg taaaccgagt cggatagctt taagtactgt tttgaggttg aagatacgat
     9781 ttttgatagg aactcatcaa ttttagattt ttaagcagca tcaataaatt gcttccttgt
     9841 tttgtcataa tttttttatt taaaaaatta tgacaaaagt gtgctattct ttttatgaga
     9901 ggtgtatgaa tatgataaat gtatgtgata aatgtatgtg atgttggaaa aagaataaaa
     9961 gaacttagaa tatcttcaaa tcttactcaa gataagattg ctgaatattt gtctttatat
    10021 ttgtctttga atcaaagcat gattgccaaa atggaaaaag gtgaaaggaa tatcacgaat
    10081 ggatttaagt aataaagctt caaatcttag aaaaaagttg ggagctgatg gtgaagcgcc
    10141 gatagatatt tttaaattgg tacaaaagat agaaaatttg acgctggtat tttatggact
    10201 cggaaagaat attagcggag tctgttataa aggaactcag ttcagtctca ttgcagtcaa
    10261 ttcagacatg tcattaggaa ggtaaagatt ttctttagca catgaactgt atcatcttta
    10321 ttatgatgag gtgaagaaga gttcagtcag tcttatcttg attggtgaag gagatgaaac
    10381 tgaaagaaaa gcggatcagc ttgcttctta ttttttaatt ttcccatctt cactgtatag
    10441 gatggttgag gaaatcagag aaaatgccaa tagaactcat cttgaagtag aagatattat
    10501 aaaattgggt cagttttatg gtatcagtca taaagctatg ttatatagat tgaggaatga
    10561 tggatacctt gatgcagaag aaattaaaaa tatggatatt agtgttatag agacagcttc
    10621 aagattaggc tatgatacaa gtttatatcg tcctttgtca gaaagtaaaa aggaaatggt
    10681 attaggataa tatattaatt caactgaaca acttttagaa aataacagaa tttcgcaagg
    10741 gaagtatgag gaactgttac tagatgcttt cagatatgat attgtatatg ggctagatga
    10801 agagggggga gttgtcgttt gactagtcgt gtatttattg atgcagattg tatttcagta
    10861 tttttatggg ttggcactga acatctttta gaaaagctct attcgggtaa aattgttatt
    10921 ccacaagaga tgtatgatga aatcaatata cctacaattc cccatttaaa atctaggata
    10981 gatcagttgg tagctaaggg ttcagctgag attgtgagca tagacattgg aactgaagaa
    11041 tacgcattat atagagattt aacaagaaat catgataata acaagattat tggtaaggga
    11101 gaagcggctt ctatttcctt agcgaaaaag cataatggga tattaggaag taataaccta
    11161 agagatgtta aatcatatgt agaagaattt tctttagaac atatgacaac aggagatata
    11221 ctgattgaag cgtttaaagc gtaatttatt actgaacaag agggcaatca tatctggaat
    11281 aatatgctta aaaagagaag gaaaattggt gcaaattcat tttcagacta tcttcgtgga
    11341 agtattcatc aaaatagaca aaaataaatt tggataaatc gaactcacta ttcaggaggc
    11401 atatgagcaa ttcgaaaaag aaaaatgtca aattgagcct ataggagtag aagtgaaata
    11461 gtaagtcctg catagtggat gagagaaaag ttctccttga agttttcctg aactatcagt
    11521 cgcatgtcaa acgatatgta gggtaatgtg agaggggata gcgagtagtt tttggttatt
    11581 ttatcaaaaa acttatattt tattatactg aatgataaaa tataataaaa atgatagaat
    11641 aaggaaaaaa catgaatgtc aaaaagataa tgtcaatttt tcaatccttt tatgttgatg
    11701 tcagtattga ggaactgact ttgactttac caatcagttt tgtaaaaagg tttgagtata
    11761 ctcaaatgac ttttcataag gaatcatttt tattgattaa agaaaagaga agggggagtt
    11821 tgagttcatt tgttactcag gctcgcacta tgggtgaaaa agccaatatg gatgttgttt
    11881 tgctgttttc gaagttatca gacagtgaaa aaaagcaatt acttcaagct agagttccgt
    11941 ttgtagactt taagggaaac ctcttcttcc ctccattggg actagtactg aatgcgaatg
    12001 atactgaagt ccctaaggaa ttaacaccta gcgaacaatt aacgtggatt gcctttttat
    12061 tgacaaaagg tcaaaaagta gtagatgttg atttgctttc acaagtcact ggacttccaa
    12121 actcaacaat ttataggtgt ttgaggactt ttaaagcttt atattggtta aacaagcaaa
    12181 ataagcttta cacatatacg gtgtcaaaga aagaattatt cttaaaatcc gtgtcatgtt
    12241 tatttaatcc catcaaaaaa cggattttat tgccagatgg cgatataaag cagataaaat
    12301 ctgtttctaa tcttctatat ggtggtgctt atgctttgtc gcattcaact tttttagctg
    12361 aaacggatga aaatattagc tatgtcatat ggcagagaaa attcaatcag ttatccttgc
    12421 cattttctca gcatatttta aaaggaaaga tgctagagat atggaaatat cgtccttttg
    12481 tatctgagtt ttggaatgat tttaaaaata atcatgataa acaatttgta gatccgattt
    12541 ctctttattt gaccttaaaa gatgatgatg acccacgtat agaggaagag agtgaagcac
    12601 tagaaaatat gatattacag tatctgggag aagatgatgc cagctaatac gaaagttatt
    12661 tttcaagaaa cgtttgcgga ttttcagaac tattatgttc tgattggggg aactgctacc
    12721 tctatcgtat tggattcgca aggatttaaa agtcgcacaa caaaagatta tgatatggtc
    12781 atcattgatg aagtaaaaaa taaggaattt tatactacct tgaatcattt tttagaattg
    12841 ggagagtatc aaggaagtca gaaagatgag aaagcgcagc tttttcgatt tacaacaact
    12901 aatcctgagt ttccttctat gattgaacta tttagtatct taccagaata tccattaaag
    12961 aaggacggtc gagaaattcc cttacatttt gaccaagatg ctagtttatc agccttatta
    13021 ttgaatgaag attattataa tatattggtg catgaaaaag aaaccattca ggggtatttg
    13081 gtattgagta attgtggtct atactcttcg aaaatctctt caaaccacgt cagcttccat
    13141 ctacaacctc aaaacagtgt tttgagcagc ctgcggctag cttcctagtt tgctctttga
    13201 ttttcattga gtattaatta tttttaaggc taaagcttgg ctggatatga gggaacgctc
    13261 tgctacaggt gctcaaggtt taagtaagtc cattaaaaag catttgaatg accttacccg
    13321 tttgacagct tccttgctag gagatgaaaa gttatcggct ataacatcaa gtagtgcggt
    13381 aaaagcagac atgcaccgct ttgtgataga attagagcct gtgaagtcaa ctattcttca
    13441 aaatgatgac atttcattag atcaaaatga aatttttgaa attctgaaaa attttttcga
    13501 tggttaaaat aattgtagcg agatggctat attgaattcg tttatatctg gaaactagaa
    13561 aaaacttcaa tttcaggaga aaatgaagtc aatcttccca caatcaaacg tatagtatca
    13621 aggtttttca agacctgata ttatgcgttt tttgcttttc aaaacttttt gcccagtttt
    13681 tgtttttatc ctctagtcac ttgatttgtt tcaggtggtt ttttagtata gtaaaatgaa
    13741 acgagaacag gacaaattga tcaggacagt caaatcgatt tctaatcaat gttttagaag
    13801 cagaagtgta ctattctagt ttcaatctac tatagttaaa tctgcggtca agtctactgg
    13861 tggatctatg attgtaatac tcttccaaaa tctcatcaac cacgtcagtc ttgccttgca
    13921 gtctgtatct tactgaccaa gctagtgatg gacttagaat aggtgatttg gagcgtccta
    13981 ttggctagga aatgctgatc atagtccttt gctgaggcta gggtgtttca acattcaaca
    14041 ctcaactggt tgatctagtt gataggaagg gaattactat aaaatactca ggcttccatc
    14101 atattttttg aaacgattgt gtaatcaaaa tgtaccaata ttgtagtatt ggtacagaag
    14161 atgttgtgaa tggataaata tatcataact gctgtctctc tatgtaaaaa gaaggttgta
    14221 tcaaaaagat ttcatatgtc tgtgcatata tataatagac tttctgcaag actagaatcc
    14281 tagttcatga tttataatgc cagcaatcaa attcattcgt aatccaaagc gtttacgatg
    14341 atttcgatag gttgttgaaa acattttaaa cgtttctact ttggcaaaga tgttctcaac
    14401 cttgcttctc tccttagata gcgcatggtt ataggtttta tcttcaactg ttagcggctt
    14461 gagtttgctg gatttacgtg gaatttgtgc ttgaggatat atcttcatga gcccttgata
    14521 accactgtca gccaagattt taccagcttg tccgactttt ttgataagct gtttttaata
    14581 cagctaatat ctcttcaaaa gtggtacgct gaacactaac aagacgctta aatcgtgcat
    14641 cagttagttg tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca
    14701 ggaagtctaa taagttatag tccagttttt actatacttt gatattcaaa tatgttatac
    14761 tatggttatc aaagtaaatg aaaggagtta cgaatatgac gccagaagaa atgtacctga
    14821 cagagcgatt agacgtacag atagctcatt ttttaaagaa aagcgttcaa catcgtaggc
    14881 gctataaggt attaaaaata acagaaatcg tggcaggttt cctcatagct gtcttttgtg
    14941 ctattcctat gccaggtgat cgctaccgtt tgatttcggt tgccttatcc agtctcggct
    15001 tgctgtgtga ggggattatc aatttgtata atgcaaagga aaattggatt tcttaccaaa
    15061 aaactgcgca actcctggag aaagaaaaat tcctctatca atgccaaacg gagaaatatg
    15121 caggaaagac caaggctttt gccctatttg tcaagacatg cgaaggtctt atctcagagg
    15181 agattaacca gtgggaaagt atccagtcaa aagaagtggc agctagtgca gatgctccag
    15241 ttaaaaaaga gtaggaggta gaggaaatgt ctcaatccag ttacctgtcg cccttgctct
    15301 ggttaaaaaa agaagccgat aaggaaaaga tgagcgcgac ccagtgccag atatttttct
    15361 tttactatca aatgtttgag ctcttatttg ctagagaaag cgacatgaaa gacttatgtc
    15421 tgggaacgaa aggtttttat ttctcgcagt tagagaaaaa tttgctttct ggagtttccc
    15481 gatttctaaa aaacttggag gggaaagtaa ctctcaaggc taaccaagaa gtatcagctc
    15541 gcaaagccct ttttctagcc ttgacaacta gccaatcaga ttggcaggag ttagctcctg
    15601 tttttgattt ttatcagact atcgggaggc ttgaaaatcc ttctctcttg agttctcagg
    15661 acagacaaca tctgatgtgg atttaccagt cagctttgga gaaggattat attgtcaagg
    15721 ttattggcga caagcatttt gtattgaaga gacaagatgc tactaaattg acagcgcgcc
    15781 aaactcaaac tttggaaatt ctgagtcaat cagaagactt ggtcaatcct gtctatgtta
    15841 cattaggaga aaagggggtg ctcttgcttg attaagagag gagatgttgt agctctttat
    15901 ttgccttttc cgactattag tagcgatttg gctgtgaaga atcatatgta tatctgtatt
    15961 gacaacagca tgactaaaaa caaagagttg gttaaaaatc agaccttcaa accagctctc
    16021 ttgaccagac gtttggtcaa gaactttatg atagaagagc cggatctagc tcgtaatcct
    16081 tttacaagac caaccttgat tgacttagat aaggtattta tgttggataa tacggttatt
    16141 ccgacttctt atctagccag acggcgacgc aatgtctcag aagaattgta cgaggaaatt
    16201 ttggatcact tagtccaacc acggctgatt tcgctgaaca agtctgagtt tatgcaactc
    16261 aatccaggaa cttattagga ggtagaagat ggcaaataaa gcagtaaatg actttatact
    16321 agctatgaat tacgataaaa agaaactctt gacccatcag ggagaaagta ttgaaaatcg
    16381 tttcatcaaa gagggtaatc agctacccga tgagtttgtt gttatcgaaa gaaagaagcg
    16441 gagcttgtcg acaaatacaa gtgatatttc tgtaacagct accaacgaca gtcgcctcta
    16501 tcctggagca cttctcgtag tggatgagac cttgttagag aataatccca ctcttcttgc
    16561 ggtcgatcgt gctccgatga cttatagtat tgatttgcct ggtttggcaa gtagcgatag
    16621 ctttctccaa gtggaagacc ccagcaattc aagtgttcgc ggagcggtaa acgatttgtt
    16681 ggctaagtgg catcaagatt atggtcaggt caataatgtc ccagctagaa tgcagtatga
    16741 aaaaatcacg gctcacagca tggaacaact caaggtcaag tttggttctg actttgaaaa
    16801 gacagggaat tctcttgata ttgattttaa ctctgtccat tcaggcgaaa agcagattca
    16861 gattgttaat tttaagcaga tttattatac agtcagcgta gatgctgtta aaaatccagg
    16921 agatgtgttt caagatactg taacggtaga ggatttaaaa cagagaggaa tttctgcaga
    16981 gcgtcctttg gtctatattt cgagtgttgc ttatgggcgc caagtctatc tcaagttgga
    17041 aaccacgagt aagagtgatg aagtagaggc tgcttttgaa gctttgataa aaggagtcaa
    17101 ggtagctcct cagacagagt ggaagcagat tttggacaat acagaagtga aggcggttat
    17161 tttagggggc gacccaagtt cgggtgcccg agttgtaaca ggcaaggtgg atatggtaga
    17221 ggacttgatt caagaaggca gtcgctttac agcagatcat ccaggcttgc cgatttccta
    17281 tacaacttct tttttacgtg acaatgtagt tgcgaccttt caaaatagta cagactatgt
    17341 tgagactaag gttacagctt acagaaacgg agatttactg ctggatcata gtggtgccta
    17401 tgttgcccaa tattatatta cttgggatga attatcctat gatcatcaag gtaaggaagt
    17461 cttgactcct aaggcttggg acagaaatgg gcaggatttg acggctcact ttaccactag
    17521 tattccttta aaagggaatg ttcgtaatct ctctgtcaaa attagagagt gtaccgggct
    17581 tgcctgggaa tggtggcgta cggtttatga aaaaaccgat ttgccactag tgcgtaagcg
    17641 gacgatttct atttggggaa caactctcta tcctcaggta gaagataagg tagaaaatga
    17701 ctaggagagg agaatgcttg cgacaaaaag aggcgatgat ctctctgcgg atatctgaaa
    17761 gtttatctct tgcctagcga tttccattgg agtatgctcg tgatgttaaa atgaatctat
    17821 caaacagaat gtgtaaaaaa gtaaaaaggg tagccaattc cttgatatac aggggattga
    17881 ttatccttta cttgttttag atgattggaa attcaagaat gacacgtatc ggaaatattt
    17941 tgctgtttat atctaatacc catttatgga aaaaatgaaa ttaaatatga acaaatcaat
    18001 tgctagcaat ggtttagaag tgccagtgta ctagtctaat ttctccatct tgggaacacg
    18061 taaattatac tcttcgaaaa tctcttcaaa ccaggtcagc cctatccgca acctcaaaac
    18121 agtgttttga gcaacctgcg gctagctttc tagtttgctt tttgattttt attgagtatt
    18181 agaggtttgc ttagaaactc ttctattgat ttcttggaat acaatagcgc ctataagaac
    18241 tgttggattt caaagtattt acttgaacta tgatatgtct ggagtagact gtcaacaaaa
    18301 ggtgcagtat gattgttttt gtcgcttata tctacaaact tcaaacagta atttgagctg
    18361 actttgtcaa acttggctga aactttctat ttgcagataa tggtctagtt tgttttttga
    18421 atgtggatga gtgtctgttg ataaagatag aaaggtaaga ccatcttagc aggtaaagtg
    18481 ctatcctagc ttgatttgct aataaaatcc atttcctcta gtgaaaatca aaaaaacttg
    18541 tgttataata agaaagatta aaatgtgaaa aaaggagatt cctaatggga cgtaaatggg
    18601 ccaatatcgt agccaagaaa acggctaaag atggagctaa ctctaaagta tatgcaaaat
    18661 ttggtgtaga aatctatgta gcagctaaaa aaggtgatcc agatccagaa tcaaactcag
    18721 ctttgaaatt cgttatcgac cgtgctaaac aagcccaagt gccaaaacac attatcgata
    18781 aagcgattga taaagccaaa ggaaacacag acgaaacctt tacagaagga cgttacgaag
    18841 gttttgggcc aaatggctct atgctaattg tggatacttt gacttctaac gttaaccgta
    18901 cagcagccaa tgtccgtgca gcctttggta aaaacggcgg aaacatgggc gcttcaggtt
    18961 ctgtttctta cctttttgac aacaaaggtg ttattgtatt tggaggtgaa gatgcggacg
    19021 cagtctttga gcaattgctc gaagcggatg tggatgtgga tgacgtagaa gcacaagaag
    19081 gtacaatcac agtttacaca gcgccaactg accttcacaa ggctatcgtt gctctccgtg
    19141 agtctggtat tgaagaattc caagtgactg aattggaaat gattcctcag tcagaagtgg
    19201 aattgtcagg cgaagacctt gaaacctttg aaaaacttta cagcgttctt gaagacgacg
    19261 aagacgtcca aaagatttat acgaacgtag atgggtttta atttaaccta tagaacatga
    19321 tcctaagtga gaaaatcact tgggattttt ttaatcaaga aaatagttct catagaaatt
    19381 taattattct ccagagaact atttttattt agaaggggga gattatggat aaaccgatgt
    19441 tagtctttaa gcgttttggt catcaaattt acctgatggt gcaaaaggaa gccaaacgtt
    19501 gcggcattga atttatgggt gggccgcaag gtcaggttgt gcgttttttg gataatcgcg
    19561 agaaaaacca agacttggtc ttgattaaag atatcgagca ggaactcaat attaccaagt
    19621 ctgttgctag taatctggtt aagcgtatag tgcaaaatgg tttggtggaa ttggaggcga
    19681 gtcctgttga taagcgggct aagtttgttc gtctgacgga caaagcacgt tctcagatgc
    19741 aacaggttaa ggcttttttt gaacgcatag acaagcagtt gatggaagac attgatgaag
    19801 atgaattact gatttttgag aaagttctcg gtcaactaca ggcaaatatc aagggaatag
    19861 gaggagagaa taaagaaatt agccaaaaga attagtagaa aagaatgggg gtgattttac
    19921 tagccattct ctttacttgc ttttcggtct atctagagtt ggaagtgccg acctatatct
    19981 cgaaaattac ggatttgcta ggtagtcaag aaactaattt agatgagttg tggcagccgg
    20041 caagcatgat gatgggaatg tcctttcttg ccttcttgtc cgtagttgca gttggatttt
    20101 ttgcatcccg agtggcggct tcttatacta gtaggctgag aagtgatatt tttaaccgag
    20161 ttttggatta ctcgcagaca gagattaaga aattttcaat tcctagcctc ttgacgcgta
    20221 ctaccaatga cattactcaa gttcaaatgt tgattactat gggcttgcaa gtggtaacgc
    20281 gtggttcaat tatggctatc tgggctattg ggaagatttt aggtcattca gaatactggc
    20341 tctgggccgt acttgtggca gtgattatca acgtcctgat gacgaccgtt ttgatgacgc
    20401 tagcctttcc aaaacagtcc ttgattcagg ggctgacaga taaactgaac agtatcactc
    20461 gtgagagttt aacaggtatt cgtgtcgttc gtgcctacaa tgcagaggat tatcaaaatg
    20521 aaaaatttgc agcagtaaat gatgaattga cccgtttgaa tttgtttgtc aaccgtctta
    20581 tggctatttt gaatcctatc atgatgggga tttcaagtgg tttgggtgta gcgatttact
    20641 ggattggggc ctatgtgatt aacgacgctg ctccgatagc gcgtctgcct ctctttagtg
    20701 acatgattgt tttcatgtct tatgccatgt aggttgtcat gggcttcctt ctcatgggag
    20761 cactcttcat cgttcttccc cgaactatgg tctctgctaa gcggattaat caagttttag
    20821 atttgcattc ttctatccaa aaccctgttc aagtgcagct gactgatgaa aacttcaaag
    20881 gtcaggtcga gtttaaggat gtgaccttcc gctatgcggc aaattcggag gcagttattg
    20941 aacatgttag ctttaaagca gaaactggtc aaacagtggc ctttattggg tcaacaggtt
    21001 ctggtaaatc aactctggtc aatctgattc cacgtttcta cgacgtgtca gcaggagaaa
    21061 ttctggtgga cggtgtcaat gttcaagact atgacttctc tgcgacagct catgctggtc
    21121 aaaaggttgc cattgttggg ccgactgggg ctggtaagac aaccattgtc aatcttttga
    21181 tgaaattcta tgagattgat aagggaagta ttcgcattga tggtgtggat accaaggcta
    21241 tgacgcgttc agaagtgcat gatgcctttt caatggtctt gcaggatacc tggctctttg
    21301 aaggaactat tcgagacaat ctcatctata atcaaatagg gattagtgat gaacgaatga
    21361 tggaagctag taaggctgtg ggaattcacc actttattat gaccttgcca gatggctatg
    21421 ataccatctt ggatgacacc gtgaccttgt ctgtaagaca aaaacaacta ttgactattg
    21481 ctcgtgccct tcttaaggat gcaccgcttt tgattttgga tgaggcgact tcttctgttg
    21541 acacacggac agaggaattg atccaaaaag ccatggaccg tttgatggaa ggacgcacat
    21601 cctttgtcat tgcccaccgc ttgtcaacca tccgaaatgc agacttgatc ttggtcatga
    21661 aagatggaaa tatcatcgag caaggcaact atgaggaact gatggcgcaa ggtggcttct
    21721 acgctgactt gtacaatagt caatttacag aagatgaagc agaagaataa atcaaaagaa
    21781 ggcttgacga ccttcttttt cttatttata ctagtacaca tagaaagaga gaagtatgag
    21841 tcagaaatta tacaatatga aatttgctgc tgtctactta gccttgattg caaaagttga
    21901 gcgaaagggt ggaaaggcag agtcagttca ccaagtgacc agttggttga cagggtatga
    21961 agtgagtgac gttcttgctt gtctggatag ggatgttact tacggagatt tttttcgaca
    22021 agcaccatat tatgtccctg aacgaattgc aattacaggg aagatttgcg gtgtccgtat
    22081 tgaggaaatt gatgattctc tgatgcagga aatacgtcgc ttggacaagc tagtggattg
    22141 gcttgccaag gggaaaacat cccaacaagt tctagaaaag tatgagaagc ataaatgaaa
    22201 aattatcaag aatggtatcg aaatatcagc tccagactaa ctagtcgtcc aattctttta
    22261 ttcctattac gcagtttcaa tcgtttgatg acagtcgcca tgcccctggt ctatctgatc
    22321 ttgctagtca ccacttacct gcaactagga cttggtcagc aagttggggt ttatgtgctt
    22381 attcctgcat caggttttgt gaccttgtcc ctgtttcgta agaaaatcaa tcacccgaga
    22441 ccttatgaaa cttgggatat ctgtcccctt cttgataagg atagttcggg acggtcgatg
    22501 cccagtcgcc atgtcttttc ggcagctatc atctccatgg cctgtctgca tgctagtcta
    22561 cctattggct tagtatgctt gaacttttca gctttgctgg ggttggtgag ggttttaggg
    22621 ggtgttcatt atcccaagga tgtcttggtt ggctatgctt gtggtctggt gtggggattc
    22681 cttttcttct tattatgaca tgtaagttaa gctagtccta caaccactta ctgcttcaaa
    22741 ttgaccactt gcttttttgc ccttgtattc ctaacttagc tttgatatag tagagtcaga
    22801 aaggagatgt gatgaagtta cgaattgaga ttgacggcaa tttagaggag actgaaattg
    22861 tcatcaaggc agcggctttg acagatgaga ttgcggattt acagcggctc ttgcaagaat
    22921 ccaagtctcc taggttgatt ttttataagg ggacgggtga atattatctg gacttgtcgg
    22981 aaattctctt ctttgagaca gaaggtagca agatttatgc ccatacccag aaaaatgcct
    23041 acgaagttcg gctcaaactc tatgagttag aggctatcct tcctcgctat tttagtcgag
    23101 tatccaagtc aacgatcgct aatattcggc aaatctattc ggtggacaag tccttttcag
    23161 gaacgggcac catttccttt tatcaaaccc acaaggaggt tcatgtgtca cggcattacc
    23221 aatccctcct aaaagaaaat ctaagaaata tgaggtaaga acatgaaaaa gaaagcattt
    23281 ggtattgttt tattggtttt agcagcttgg atcttgctgc aagggaattt tggaattcct
    23341 tctctaggag ggcacatttg gcccttgatt ggtattgctt tttttgccta ccaatcagtt
    23401 ggagctttgt tgcgtcgcca cttaacttca gcctctttta cagctctagt agccttaatg
    23461 attgctaacc acttttatgg cattttaccg attccaaacc agacactaat ctgggcagga
    23521 gttctaatcg ttctcggagt aaatatgttg actcattcta acagaacttg gaatgggaaa
    23581 aaatggtggt acaatgggaa aaaaacagtc gtcacggata aggaagtcgc ttttggtagc
    23641 gggaccttct ataagcaaga tcaagatctc gtagatgacc aagtggaagt cgcttttggg
    23701 gatgctaaaa tctactatga taatgcagag atgctaggtg attttgcaac tttaaatatt
    23761 gaagtggcct tcggaaatgc aaccgtctat gttccacaac actggcgtgt agatttgaaa
    23821 gtagaaacct cctttggtgc agctaaggct gacgctcctg tagccccaac cagcaaaacc
    23881 ttgactatcc gtggagatgt ggcttttggg aagttggaaa ttgtctacgt taaataaaaa
    23941 aatcttcact tcaaccatca aaatagacgt actaagagta ggaaattgat gccttgctct
    24001 gatttcagtt ctatggttgt tagactttaa aaaatgaaat gctgccttta aaagttgtat
    24061 atttttcgat attttggctt ttacgtttga tgtatctatg tactacagcg tagatgatgt
    24121 agtgtcaaat gcttttaaaa aacgaatgat attggacagt ttttttgcct ttaattgctc
    24181 aggaaccatg aaagtcagta cttgggttta tgacaaggga gaatggtatt atgtaagttc
    24241 ttctggttcc atgattgcga atgattgggt caaagacaat ggcaagtagt attatctggc
    24301 ttcatcaggt aagatgcttc gcaataccta cacacctgat ggttactacg ttggcaactt
    24361 aggtgcctgg caataagaat aatactcttt gaaaatctct tcaaaccacg ccagcttcat
    24421 ccacaacctc aaaacagtgt tttgagctga cttcgtcagt tctatctaca acctcaaagc
    24481 agtgctttga gcagcctgcg gctagcttcc tagtttggtc tttgattttc attgagtata
    24541 agaagtcctt ttccttaaag gaagaggctt tttacttgct tttctgctgc ttcctcattt
    24601 gtcctgaagc cttttttgtg ttaaaatgaa tggtatgaaa gctaaaaaaa tgtggatggc
    24661 aggcttggct ctgctaggta tcggaagcct tgctcttgcc acgaaaaaag ttgcagatga
    24721 ccgtaagctc atgaagactc aggaagagtt gacagagatt gtgcgagacc atttttccga
    24781 catgggggaa attgcgaccc tctatgttca agtttacgaa agcagtctgg agagcttggt
    24841 tggtggcgtc atttttgagg atggtcgtca ttataccttt gtctatgaaa atgaagacct
    24901 agtctatgag gaggaagtct tatgatacag ccagcaagtt tagaagaatt agcatcttta
    24961 gtggaaaaag cgggcaagaa ggtcttcctt tttgtggcag actggtgtgg cgattgtcgt
    25021 tatatttatc ctgccttacc agagattgag gagaccaatc cagagttcac ctttattcga
    25081 atggaccgag atcagtatat ggatttggcc aaactctggg atgtttacgg aattcctagc
    25141 cttgttgttc tagaaaagga caaggaaatc ggtcgttttg tcaatcgcga ccgtaaaagt
    25201 aaggagcaaa ttaacgattt tttagcagga ttgaaatagg agaaaaagga aacaatgatt
    25261 tttacgtata acaaagaaca tgtcggtgat gtccttatgg tcatcgtgaa aaatagcgga
    25321 gatgccaaac tgaatgtgga acgcaaaggc aaggtagccc gtgttttcct caaagaaaat
    25381 ggggaaacag tagcttggaa catttttgag gtttcgagct tgtttgaaat tgcagagcgc
    25441 ggtcaagtct ttttatcaga tgagcaagtc gctcgtttga accaagaatt acaggcggaa
    25501 ggttttacag aagaaattgt taatgataag gaacctaagt ttgttgttgg tgaaattgtc
    25561 gagatggtag ctcatccaga cagtgaccac ctcaacatct gccaagttgc agtcgcaagt
    25621 gacaagatag tgcaaatcgt tgcaggagca cctaatgcgc gtgttgggtt gaaaaccatt
    25681 gtggctcttc ctggtgccat gatgccaaaa gggaatttca ttttcccagg cgaacttcgt
    25741 ggtgaaaaga gttttgggat gatgtgtagt cctcgtgaat tgcatttgcc aaatgctccg
    25801 caaaaacgtg gggtgcttga attatcagaa gaccaagttg tcggaacacc gttcgaccca
    25861 gcgaaacact ggactgccta ggaacttgtc agcatctgat agaaggaaat aagatggcaa
    25921 aaaatgtagt gattacggga gcaacctcag gaatcggtga agcgattgcg cgtgcttatc
    25981 tggagcaggg tgaggatgtc gttctaacag gacgacggat agacagacta gaagctctta
    26041 aggcggagtt tgcagaaact tttccaaatc aaacagtttg gacttttctc ctagatgtca
    26101 cggatatgac aatggtaaag actgtctgct ctgatatttt agaaacgata ggtcagattg
    26161 acatcctggt caataacgca ggactggctc ttggcttagc tccctatcaa gactatgaag
    26221 agttggatat gctgaccatg ttggatacca atgtcaaagg tttgatggca gtcactcgct
    26281 gtttcttgcc agcaatggta aaagccaatc aaggtcatat tatcaatatg gggtcaaccg
    26341 caggaattta tgcctatgct ggtgcagctg tttactcagc caccaaggcg gcagttaaga
    26401 ccttttcaga tggactgcga attgatacca tcgcaacgga tatcaaggtg acgaccattc
    26461 agcctggaat tgtcgaaaca gatttttcta cagtgcgttt tcatggtgat aaagaacgag
    26521 ctgcgtccgt ttaccaagga atagaagcct tgcaagctca ggatattgca gacacagtag
    26581 tctatgtgac cagtcagcct cgccgtgttc agattacaga tatgaccatt atggccaatc
    26641 aacaggcgac aggtttcatg gttcataaaa aataaaaaat tttctcgaaa agttacaaat
    26701 ttctgtaact ttttttgatt tcctacgaat agataagtag gaggaagaaa atatgtataa
    26761 taaagttatc atgattggac gtttaacgtc tacaccagaa ttgcacaaaa ccaacaatga
    26821 caagtcagta gcgcgagcaa ctatcgctgt caaccgtcgt tacaaagacc aaaacggtga
    26881 acgtgaagct gattttgtca atatggttct atggggcaga ctagcagaaa ctttggcaag
    26941 ctacgcaacc aaaggtagtc tcatttccgt tgatggagaa ttgcgtaccc gtcgctttga
    27001 gaaaaatggt cagatgaatt atgtaaccga agtccttgtg acaggattcc aactcttgga
    27061 aagtcgtgcc caacgtgcta tgcgtgaaaa taatgcaggc caagatttgg cagatttggt
    27121 cttggaagag gaagaattgc cattttaaga attaaaaagt ctgagttggt ctcaggcttt
    27181 ttatcttgag aaagtcagac ttttttcttg attatttctg actaagtgat acaatagaac
    27241 tatgaattag cactcaggta taaagagtgc taataatatc tatctcatta tggaggaaat
    27301 cagatgttga aaccattagg ggaccgtgtg gtcttaaaag tagaagaaaa agaacaaact
    27361 gttggaggct ttgttctcgc aggttcagcc caagaaaaaa ccaaaacagc ccaagttgtg
    27421 gctactggac aaggtgttcg taccttgaac ggtgacttgg ttgctccaag tgttaaaact
    27481 ggagatcgtg tcttagttga agcccacgca ggtcttgatg tcaaagatgg cgatgaaaag
    27541 tacatcatcg taggcgaagc taacattttg gcaatcattg aggaatagaa ggagaaagta
    27601 agtatgtcaa aagaaattaa attttcatca gatgcccgtt cagccatggt tcgtggtgtc
    27661 gatatccttg cagacactgt taaagtaacc ttgggaccaa aaggtcgcaa tgtcgttctt
    27721 gaaaagtcat tcggttcacc cttgattacc aatgacggtg tgaccattgc caaagaaatc
    27781 gaattggaag accattttga aaatatgggt gctaagttag tatcagaagt agcttctaaa
    27841 accaatgata tcgcaggtga cggaactacg actgcaacag tcttgaccca agctatcgtc
    27901 cgtgaaggaa tcaaaaacgt cacagcaggt gcaaatccaa tcggtattcg tcgtgggatt
    27961 gaaacagcag ttgccgcagc agttgaagct ttgaaaaaca acgccatccc tgttgccaat
    28021 aaagaagcta tcgctcaagt tgcagccgta tcttctcgtt ctgaaaaagt tggtgagtac
    28081 atctctgaag caatggaaaa agttggcaaa gacggtgtca tcaccatcga agagtcacgt
    28141 ggtatggaaa cagagcttga agtcgtagaa ggaatgcagt ttgaccgtgg ttacctttca
    28201 cagtacatgg tgactgatag cgaaaaaatg gtggctgacc ttgaaaatcc gtacattttg
    28261 attacagaca agaaaatttc caatatccaa gaaatcttgc cacttttgga aagcattctc
    28321 caaagcaatc gtccactctt gattattgcg gatgatgtgg atggcgaggc tcttccaact
    28381 cttgttttga acaagattcg tggaaccttc aacgtagtag cagtcaaggc acctggtttt
    28441 ggtgaccgtc gcaaagccat gcttgaagat atcgccatct taacaggcgg aacagttatc
    28501 acagaagacc ttggtcttga gttgaaagat gcgacaattg aagctcttgg tcaagcagcg
    28561 agagtgaccg tggacaaaga tagcacggtt attgtagaag gtgcaggaaa tcctgaagcg
    28621 atttctcacc gtgttgcggt tatcaagtct caaatcgaaa ctacaacttc tgaatttgac
    28681 cgtgaaaaat tgcaagaacg cttggccaaa ttgtcaggtg gtgtagcggt tattaaggtc
    28741 ggagccgcaa ctgaaactga gttgaaagaa atgaaactcc gcattgaaga tgccctcaac
    28801 gctactcgtg cagctgttga agaaggtatc gttgcaggtg gtggaacagc tcttgccaat
    28861 gtgattccag ctgttgctac cttggaattg acaggagatg aagcaacagg acgtaatatt
    28921 gttctccgtg ctttggaaga acccgttcgt caaattgctc acaatgcagg atttgaagga
    28981 tctatcgtta tcgatcgttt gaaaaatgct gagcttggta taggattcaa cgcagcaact
    29041 ggcgagtggg ttaacatgat tgatcaaggt atcattgatc cagttaaagt gagtcgttca
    29101 gccctacaaa atgcagcatc tgtagccagc ttgattttga caacagaagc agtcgtagcc
    29161 aataaaccag aaccagtagc cccagctcca gcaatggatc caagtatgat gggcgggatg
    29221 atgtaagctt tctatagaaa acaacttata aaaaacacaa aaggagggaa tgactaaccc
    29281 ttctttttat aatattcact tctaaattga tttgagctct cctaacttat atgataaaat
    29341 aagactagaa aaaggagaag aacatgatcg atgtagaaga aattctgtgc aagatgaccc
    29401 ccaatcagaa gattaattat gaccgtgtca tgcagaaaat ggtacaagca tgggaaaaaa
    29461 atgagtagcg gccaaccatt ctcgtgcatg tttgctgtgc cccttgtagt acctatacac
    29521 tagaatattt gaccaagtat gcagatgtga ccatctattt tgccaattct aatatccatc
    29581 ccaaggcaga ataccataag cgggtctatg tcaccaagaa atttgttagt gattttaatg
    29641 agcggacagg aaatacggtt cagtacctag aagctcccta cgaacccaat taataccgaa
    29701 aactagttag ggggctagag gaggagcccg aaggtggcga ccgttgcaag gtttgttttg
    29761 actaccgact ggataaaaca gcgcaagtgg ctatggactt gggctttgac tactttggtt
    29821 cagccttgac catcagtcct cataagaatt ctcaaactat caatagcatc ggaatcgatg
    29881 tgcaaaaaat ttacacgccc cactatcttc ccaacgattt caagaaaaat caaggctaca
    29941 aacgttcagt agagatgtgt gaggagtatg atatctatcg tcaatgttat tgtggctgcg
    30001 tctatgcagc ccaagcccag aatattgacc tggtttaagt taagaaggac gccacagcat
    30061 gcttgttgga taaggatgtt gagaaagact attctcatat caaatttata gtagattgaa
    30121 actagaatag tacaccttta cttctaaaac attgttagaa atcgatttga ctgtccttat
    30181 ttcattttac tatactgtta cgaaattaga tatataaatg aaaacttgcc tcaaggtagg
    30241 ttttttgcta gtagaaaagc gatagacaga aattgttgga ctcttaaaaa aatgaagttt
    30301 tgctcaaaag agctttttaa attaaaacga gcaattatca gttcaaatct gtttcaaaag
    30361 aagaacggat aaattaatcg atgctttgtt tttgagttag gaagttaagc atgccaaact
    30421 gagtcgtagg aataaatttc tttatagaaa tgtgttacaa ctctgctata acggaatatt
    30481 ccttttttgc atttatataa cttatttaac actatcttta ttcttgtgat ataatgccaa
    30541 attatagagt ggaggtcatt taaaatgatt gataaagtaa ttgaacaata taaaagtcat
    30601 gataatcttg atattcgagt agaattgcat aagaagtatt caaaaaataa attgggattt
    30661 aataattgga tattttctaa ctaccaaatc actgatgaag taaaggttct agaattggga
    30721 tgtggtacag gagaattgtg gaaaagtaat agtgattcta tagataaaat gaagcagttg
    30781 attgttacag atttttctaa agatatggta aaatcaacga agtcagtgat tggaaataga
    30841 aacaatgtca attatgagat aatggatatt caaaagattt cttttgagaa tgaaactttt
    30901 gatattgtta ttgctaatat gcttctacat catgtgaatg atattcctaa agctctctct
    30961 gaggtgaata gggtcttaaa aaccggagga attttttact gtgctacatt tggtgaaaat
    31021 ggagttgtaa attatttggc aagtttattt aaagatgagg ttaatcaaga tttagaaaat
    31081 agaacgttta ctttacaaaa tggtaaaagg tacctgagta ggtattttaa ctctgtcgat
    31141 acattactct atgatgatga gttacaggta actagtatag atgacctagt taaatacatc
    31201 caatcgttta aaggaatttc agaaataggt tcactagaag aggaaataat acgtaaaaga
    31261 ttggaaagtg agtttaataa tggtatgttg atcattccta aagaatatgg tatgtttatc
    31321 gctcgaaaag aaagttaagg gaatgaaagt gtgaaaaatt acggagaagc ttttcgatat
    31381 tttagaaaat taaacggata ttctttagag tatgctgcag ctgattctat atcaaaatct
    31441 caactttcta gatttgaaag gggagaaaat gaaatttctc tttcaacatt ttttgaatta
    31501 ttatcaaata tcaatgtttc gatagagaat ttttgtaatc acttagaaca ttataaaaga
    31561 tcggagcgtg atgatttttt ggttaattta tctccaaatt tttatagttt gaatattaaa
    31621 ggattggagg taataaaaaa taagcaacaa aaactttttg agaagagtgg aaaaaaactc
    31681 ataaaataaa tacaattatg gttcagggat tatgaaatca gctagattgt aatcatgtag
    31741 ttagtagaga tgatctaaat ttagtatatg actatttatt ccagaaggaa cgatgggagt
    31801 cctatgagat aacgctgatt ggtaatttat atcatctttt tgaaatagat tatatttaca
    31861 tggtcggaaa agaaatacta gagcgtacac attattacga aaaaatcggc aagaatagaa
    31921 atttagttgt gtcagcttgt ttaaattttt ggttctgttg ccttgaaaat tcacatctaa
    31981 tatatgcaga ctactttgaa atgaaattac aaaaattatt aaaagatgac acaaaagttt
    32041 ttgaaaaatc tacattcaa
//
LOCUS       DAVMBH010000023        29661 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVMBH010000023 DAVMBH010000000
VERSION     DAVMBH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.023"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(140..1501)
                     /gene="dnaA"
                     /locus_tag="VYP30_001162"
     CDS             complement(140..1501)
                     /gene="dnaA"
                     /locus_tag="VYP30_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1808166.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1714..2472)
                     /locus_tag="VYP30_001163"
     CDS             complement(1714..2472)
                     /locus_tag="VYP30_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1808167.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKKQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2530..3711)
                     /locus_tag="VYP30_001164"
     CDS             complement(2530..3711)
                     /locus_tag="VYP30_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1808168.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3894..4373
                     /gene="rlmH"
                     /locus_tag="VYP30_001165"
     CDS             3894..4373
                     /gene="rlmH"
                     /locus_tag="VYP30_001165"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1808169.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4417..4490
                     /locus_tag="VYP30_001166"
     tRNA            4417..4490
                     /locus_tag="VYP30_001166"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4451..4453,aa:Arg,seq:tct)
     gene            4655..4780
                     /gene="comC"
                     /locus_tag="VYP30_001167"
     CDS             4655..4780
                     /gene="comC"
                     /locus_tag="VYP30_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1808170.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4801..6126
                     /locus_tag="VYP30_001168"
     CDS             4801..6126
                     /locus_tag="VYP30_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1808171.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6123..6875
                     /locus_tag="VYP30_001169"
     CDS             6123..6875
                     /locus_tag="VYP30_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808172.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6927..6998
                     /locus_tag="VYP30_001170"
     tRNA            6927..6998
                     /locus_tag="VYP30_001170"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6960..6962,aa:Glu,seq:ttc)
     gene            7004..7077
                     /locus_tag="VYP30_001171"
     tRNA            7004..7077
                     /locus_tag="VYP30_001171"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7038..7040,aa:Asn,seq:gtt)
     gene            complement(7118..7660)
                     /locus_tag="VYP30_001172"
     CDS             complement(7118..7660)
                     /locus_tag="VYP30_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1808173.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7838..9399
                     /locus_tag="VYP30_001173"
                     /pseudo
     CDS             7838..9399
                     /locus_tag="VYP30_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(9429..11981)
                     /locus_tag="VYP30_001174"
     CDS             complement(9429..11981)
                     /locus_tag="VYP30_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1808174.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEVIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12043..13665)
                     /locus_tag="VYP30_001175"
     CDS             complement(12043..13665)
                     /locus_tag="VYP30_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1808175.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13871..14896
                     /gene="trpS"
                     /locus_tag="VYP30_001176"
     CDS             13871..14896
                     /gene="trpS"
                     /locus_tag="VYP30_001176"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1808176.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15048..16526
                     /gene="guaB"
                     /locus_tag="VYP30_001177"
     CDS             15048..16526
                     /gene="guaB"
                     /locus_tag="VYP30_001177"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1808177.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16577..17674)
                     /gene="recF"
                     /locus_tag="VYP30_001178"
     CDS             complement(16577..17674)
                     /gene="recF"
                     /locus_tag="VYP30_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1808178.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(17677..18045)
                     /gene="yaaA"
                     /locus_tag="VYP30_001179"
     CDS             complement(17677..18045)
                     /gene="yaaA"
                     /locus_tag="VYP30_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1808179.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18204..19454
                     /locus_tag="VYP30_001180"
     CDS             18204..19454
                     /locus_tag="VYP30_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1808180.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYPSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19451..20734
                     /locus_tag="VYP30_001181"
     CDS             19451..20734
                     /locus_tag="VYP30_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1808181.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20776..21597
                     /locus_tag="VYP30_001182"
     CDS             20776..21597
                     /locus_tag="VYP30_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1808182.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVTLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21608..22153
                     /gene="pgsA"
                     /locus_tag="VYP30_001183"
     CDS             21608..22153
                     /gene="pgsA"
                     /locus_tag="VYP30_001183"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1808183.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILASAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22150..22977
                     /locus_tag="VYP30_001184"
     CDS             22150..22977
                     /locus_tag="VYP30_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1808184.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22962..23801
                     /locus_tag="VYP30_001185"
     CDS             22962..23801
                     /locus_tag="VYP30_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1808185.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23794..24588
                     /locus_tag="VYP30_001186"
     CDS             23794..24588
                     /locus_tag="VYP30_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1808186.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24647..25465
                     /gene="mreC"
                     /locus_tag="VYP30_001187"
     CDS             24647..25465
                     /gene="mreC"
                     /locus_tag="VYP30_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1808187.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25465..25959
                     /gene="mreD"
                     /locus_tag="VYP30_001188"
     CDS             25465..25959
                     /gene="mreD"
                     /locus_tag="VYP30_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1808188.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26053..27231
                     /locus_tag="VYP30_001189"
     CDS             26053..27231
                     /locus_tag="VYP30_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1808189.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27455..28234
                     /gene="rpsB"
                     /locus_tag="VYP30_001190"
     CDS             27455..28234
                     /gene="rpsB"
                     /locus_tag="VYP30_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1808190.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEAGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28313..29353
                     /locus_tag="VYP30_001191"
     CDS             28313..29353
                     /locus_tag="VYP30_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1808191.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
BASE COUNT         9446 a         4711 c         5897 g         9607 t
ORIGIN      
        1 tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga aaacagcctt
       61 taaacaagtc ctatcaagtt ttttagcttg tttaaaaaat gtggataaaa aagataaaaa
      121 actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt tctaaacgta
      181 aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg actgtggtat
      241 gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt agttctctag
      301 ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta cttcccttca
      361 tttctttgat actaacacca taaaagttac caacttcagt ttggatttta tcaattggga
      421 tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca gcaatatcaa
      481 tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg atggctccct
      541 caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta tcactttgga
      601 aattgtagcc taaatgttcc gtcttacttt gtaaaatggc aatacgtgtt tcaaagtcag
      661 ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc tcctcgagcc
      721 cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc ttgtcatgaa
      781 gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg ctgagtgact
      841 gtatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac ttttccattt
      901 ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg atatatttaa
      961 cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat aagtgagtct
     1021 taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc aaatcttcag
     1081 agacagctaa agcggctgat acagcccaaa catttccatc cccttgaata aagttatcaa
     1141 aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac tttggactat
     1201 agtcataaag agttaaattt gtagcttctt caacttgtga gctagtcgta tcttgaggtt
     1261 tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca gctactacaa
     1321 taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt agaaatatag
     1381 tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa tcatacatgg
     1441 atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt ttttctttca
     1501 attctttctc ctcctttact atttaaaagt ttaatactag agatatttta ccatagatag
     1561 caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt tatccacagg
     1621 ttggggataa aagaagaaat tattgattta ttaagctttt tatcgaaaaa catagtggat
     1681 aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga taattctact
     1741 atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt tagatagttt
     1801 aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt gtatgaaatg
     1861 attagttttt tgctgtttct tttgtttttt ctctgtcaga agagtttcta acttccttac
     1921 agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgtttct tatttaaccc
     1981 aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg agagaatctg
     2041 ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact tgcccatctt
     2101 atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg cgcgtgcttc
     2161 ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga ccatcatctc
     2221 ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta aaagtgaagc
     2281 ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt gacgaacaat
     2341 aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta gtttttctct
     2401 atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag aaatcatttc
     2461 aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct ttctttacat
     2521 agatgtcaat caagattcta aatcacctga actcttgtta agtttgatag aggtagtttc
     2581 ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat ggttgtaaag
     2641 agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg taattacatc
     2701 gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa caactacacc
     2761 agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca cattagataa
     2821 attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt ctaactgttc
     2881 aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta cagatgttcc
     2941 tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa tattgatcag
     3001 tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt ttgtagaaat
     3061 agcttgtcca tcttccgatc ttaaggatac atttctattg agactggata cgataccttg
     3121 agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag cagtttctcc
     3181 tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt ctgaagagat
     3241 tttgacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag gtactttagt
     3301 cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat tgttggtgac
     3361 gatgtaagct tctttatcat tctttttata aataactcca gatccttcac tagagattcg
     3421 ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt ttgccgaata
     3481 agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg ttgaattttc
     3541 gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta cactactttt
     3601 ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc taatgacgat
     3661 aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca tatttgcctc
     3721 catatgtttg aattactgaa agtataaact gactagctta attataactt aaacacaaaa
     3781 attttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt gaaatctatt
     3841 ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga gtcatgaaaa
     3901 ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt atcgcagagt
     3961 attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca gatgaaaaaa
     4021 caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa ggtcagagaa
     4081 ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa gggaaaactt
     4141 tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga ttttctactc
     4201 ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat agagccaatc
     4261 tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta gttcttgttg
     4321 aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa tagaaaattg
     4381 acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca gctggataga
     4441 gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca atataatagc
     4501 aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag aaaaaaatga
     4561 tagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt ttgtaagtta
     4621 gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta aattggaaca
     4681 gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga tgaggttgtc
     4741 aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg ggaaagagta
     4801 atggatttat ttggatttgg gacggttatt gttcattttt taattattag tcacagttac
     4861 cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg tgcttataca
     4921 ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga tgggttaggg
     4981 attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat gaaacagtat
     5041 gagagggata gaggactatt cctaagttta ctactatctc ttttatatga gagcactcat
     5101 aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt acaatatcat
     5161 ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa aatcatttac
     5221 tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt cttgaaaaaa
     5281 gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat ggtaagtacg
     5341 attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat ctctctcctt
     5401 ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat tgctttgaag
     5461 cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt tggtctgtat
     5521 aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat gcagatggca
     5581 attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt agtcaaagca
     5641 aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat agaagactca
     5701 gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg tgtagagttt
     5761 acactggaag taaaagatac gattaccaag cttccaattg aactattgga tttggttcgt
     5821 atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta taaaaagcag
     5881 atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca gaattcatgt
     5941 aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac taagggaaga
     6001 aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa caatattatt
     6061 ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa gagggaattt
     6121 gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta gagagaatat
     6181 tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg ggaaaagtcc
     6241 gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc ctagatatcg
     6301 atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt cattacaatc
     6361 cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta acctataaat
     6421 accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg tttaagaaga
     6481 gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa gatgttgtag
     6541 attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat gatattttgt
     6601 atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat tttgcaaaag
     6661 agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag cgattttatt
     6721 ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat cgaaaaaact
     6781 tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa attagaaaat
     6841 taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag aaattgatat
     6901 aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga caccgccttt
     6961 tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca tagctcagtt
     7021 ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact ggcggagtat
     7081 agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca ccaagcattt
     7141 tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca atccaagttt
     7201 ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat tcggtggtat
     7261 ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata tgaagtttat
     7321 ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca gccagaagtg
     7381 gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt
     7441 tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca atcatatcat
     7501 acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt tctactaatt
     7561 tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata gcattttcaa
     7621 tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct tgtaaacaaa
     7681 ttagactata tgtctaaaaa tagatttttt atcttgtaat ttagattttt taatgtataa
     7741 tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag tttaaagaat
     7801 ggaaagcaat ttaaaaaaaa caacctttat tattgtcatg atcgggattt ctcttattcc
     7861 agctctgtac aatatcatat ttttgtcatt aatgtgggat ccatatgggc aattgtctga
     7921 cttacctgtg gcagttgtaa ataatgataa agaggcttcc tataatggta atactatggc
     7981 aataggaaaa gacatggtgt ccaatttaaa agaaaataaa accttggatt ttcattttgt
     8041 agatgaagag gaaggaaaga agggattgga agatggcgat tactatatgg tagtgacttt
     8101 accaagtgat ttatctaaaa aaacaactac attatccaat attcaatcga cagcagctta
     8161 tcaatcattg acaagtgagc aacaaactgg gataagtgat tctgtatctc aaaattcaac
     8221 tgatagtatt caatcggctc agtcaattgt agctttagta caaggtttac agggaagttt
     8281 agaaaactta caaaatcaat cttctaatct ttcgacttta aaaaatcaag ctaatcaagt
     8341 attacctatt acttctactt ctttgatagg attgtcaagt ggattaacag agatacaagg
     8401 agctgttact agcaaattag ttcctgccag tcagttgatt gcatcaggtg taaacgcata
     8461 tactacaggt gttgataaag tttctcaggg cgcaagtcaa ctaagtgaaa aaaatgccac
     8521 cttgacacaa aaatcttcta gattgacagc aggagttgat aaattacaat caggatctgg
     8581 gcaattagca gacaaatcca gtcagttact ttcaggtgct tcttcattag agaatggagc
     8641 taataaattg gcagatggat ctgggaaact agcagaaggt ggaacaaagt taacttctgg
     8701 attggaagat ttacagacag gacttgcttc tttaggacaa ggactaggta atgctagtga
     8761 tcaactcaaa tcagtatcaa cagaatctaa aaatgcagag attttgtcaa atccactcaa
     8821 tctttcaaaa acagacaatg atcaagttcc tgtaaatgga atcgcaatag ctccttatat
     8881 gatatcagtt gctctttttg ttgcagcaat atcaacaaat atgatatttg cgaaattgcc
     8941 ttcaggacgt catccagaga gccgttggcc ttggttgaaa tctcgagctg aaataaatgg
     9001 tattatagct gttttggcag gaattttggt atatggagga gttcagctta ttggtttaac
     9061 tgctaatcat gagatgagaa tatttattct catcatccaa acaagtttag tattcatgtc
     9121 tatggtgacc actttagcaa cgtggaatag ccgtatagga gcttttttct cacttatttt
     9181 gcttttacta tagttagcat caagtgcagg tacttatcca cttgctttga caaatgattt
     9241 ctttagatct attaatccct ggttaccaat gagctattca gtttcgggat tacgacaaac
     9301 aatctctatc aacaagtcat tttcctagct gtcatactag ctctatttac tggtttaggt
     9361 atgctagcct atcaacataa gaaaatggaa gaagattaaa aaaatcgacc gattaactgg
     9421 tcgatttttt atgccttaga tgactttcgt ctgtgattat agattccaaa tagtaagaga
     9481 gaagtaaagg aacagattgc tccagtaata aaaccattgg gaatgaagga aagtgtaata
     9541 gttcctttcc ccttgggaat gtcaactttc ataaatccag tttgagcttg tttaatttct
     9601 attttcttac catcttggta ggcagaccaa cctttgtcat aaggaatggt gaagaaaata
     9661 gatgtatctt gttggacatc atatgtagca aaaaccttgt ttttagaagt tgatactgtg
     9721 acaggttgtt ctttaatttt ttgaattacc tcggtgaaag ttttggtatc taaacgatag
     9781 aaggtaggag attcaaatga tacttgtgaa tttccaggga aactaacatt gatattgaaa
     9841 gtttttttct ctttagtata tcctagatta aagaaggaga agacattatc agttgtaaaa
     9901 gtcttttttt caccatttac aaggatgtca accttctttt gtttatcgtt agaaaagtga
     9961 aggtttatga aagagagata aacttggctg ttttctggaa cttcaatttg atactggatt
    10021 gctgcatctt catttgaaga acttgtgaca ctaatcaaat cattagtatt ttctattttt
    10081 tctgtttttt cataaggtat tggagaaaaa taatcaaaat tgacgttagc aagttgattt
    10141 aaaaatgagg cctgattatc caaggtatgt tcattgaact tgacatcatt gtaaacagat
    10201 tgactagcaa ctgcaatcgg aagagagtat tgattttcat atagggtaag attatctttt
    10261 tgatagatat ctttaaagcc atacttatca ataggactgt ctgagatatt gtactggata
    10321 ccaaataaac tatcagccaa aatactatta tttgcatatc ggagattgag attagtccca
    10381 gaggatttaa aaccaagttt atctaaagta gagcttgatg aacgatttcg aacagatgaa
    10441 aattgagaga ttccattgta gttgaatttc atactgtcat ttcctgtctg agtttgtagt
    10501 ttttcagtac gagtaaattg atttccaata tatgttgaga aagattccat agctgggata
    10561 tctcgactat aagcacttcg agaagcaaat ccccattcct tagcaattcc gtccatttga
    10621 gatgaagcat ttaaactcat ttcaaccagt ataaataaag agattagaat ggcaaataga
    10681 ttcacagata taaacttttt gataactgca aggagtaaaa gagaatagac aaccaaaaat
    10741 tcaagagtaa gcagaatatt caaatctgtt aaaaaagaat aatgcgattt tagatagatg
    10801 gtagctaaaa atcctgctac tacaagaaaa agcgaaacta aaaaattcca gactttaagt
    10861 tctttcagac gctttaagac ttctgctgct gtgtaaatta acaaggtaga gaaaatccaa
    10921 gcatagcgat gtaaaaacat gtttggagta tgcatgcctt gccaaaataa gtcaagagct
    10981 tctatgtaaa agcttgcaat tagaaatgca aagaatatta catatatgag tttcacgtga
    11041 aacttaatag atttcagcgt aaaaaataaa atggtcaaaa taaagggaaa tagtccaaca
    11101 aaaatcattg ggatggcccc atactttgtt gtgtcaaagg aaccaatgaa ttgcttagca
    11161 aagagatcaa gataccagct actttcagtt tgaaactttg taacttcagt caatttttcc
    11221 ccatgtgtct gtaaatcaaa tagagtggga agagtcataa tcaaactagc cataccagct
    11281 aaaaaggaga taactatgaa atcaagaaca gatgattttc gagtcttaaa gtcccacgaa
    11341 atttgacaga gataccagaa aataagaaac aatactgtca tatatccaaa ataataattt
    11401 tgaataaata agattgacag acttgtaaag tacaatagga gtttcttttc agttatcagt
    11461 agatgtaaac cagttataat taaaggaatc aagataaaaa catctagcca ggtttttatc
    11521 tctaattgac tgacagtgaa actcatcaga gcataggaag tagataaggc tagttttaaa
    11581 gtctgaggga tagattgaaa caatttattc aaactaaaaa aggttgacag accaatcaat
    11641 ccaaatttta agagagttgt cagatagata gcatctggca tattcgttag atcaaaaaag
    11701 taaaccagag gcgcgagaaa actacccaag taataactag atagggcata gaagtttagc
    11761 cctagaccac ttgtaaaggt gtaaaacaga ctactatttc catgtaggat atttcgtaag
    11821 gctacatcaa aaataacgta ttgatgaaag ccatctccta atagaggaga gttgtcgcta
    11881 ttccagtaga taccttgaga tagatatact ccagacataa tcactacagg aatgatgaaa
    11941 gaaataaaat aggttcgata tgtttttaaa aatgatttca tgttacctcg tagaatgata
    12001 gaaaactcag ttggttaacc caactgagtt ttgaagtttt atttagtctt tccaaagttc
    12061 tttaactttt gcttgtactt ctgcattttc taggaattca tcgtaggttt catcgatacg
    12121 gtcaatgacg ccatttttag ataagacaat gatatggtta gccaaagttt gaataaattc
    12181 gtggtcatgg ctggcaaaga tgattgattc tttaaagttt ttcaatccat cattcaagct
    12241 tgagatagat tccaagtcca agtgatttgt tggatcatca agtacaagga catttgattt
    12301 taagagcatg agttttgaaa gcatgacacg aactttttct ccccctgaca agacatttac
    12361 aggtttgtta acttcatctc cagagaagag catacggccg aggaagccac gtaggaaagt
    12421 attgtcatct tcttctttac ttgcgaattg acgcaaccag tcaagaattg attctcctcc
    12481 tgcaaaatca gctgagttat cttttggtag gtaagattga ctagttgtaa ctccccactt
    12541 gacagttcct tcatagtcaa tatctcccat gattgcacga attaatgcag tcgtttgaat
    12601 atcattttgt ccaataagtg ctgttttatc atctggacgc aagatgaaac taatattatc
    12661 caagatagtt tcaccatcaa tctttacagt tagattttct actgtcaaga gatcattacc
    12721 aatctcacgt tccgctttaa agttgataaa tggatattta cgactagatg gcacaatctc
    12781 ttctagctca atcttatcaa gcattttctt acgtgatgtt gcctgccttg acttagaagc
    12841 attggcagag aaacgagcaa caaattcttg caattgttta attttttctt ctgctttagc
    12901 attacggtct gctagcaatt tagcagcaag ctcagaagat tccttccaga agtcgtagtt
    12961 tccgacatag agtttgattt ttccaaagtc aaggtcggcc atgtgagtac aaactttgtt
    13021 taagaagtga cggtcgtggg atactacgat aactgtgtta tcaaagtcaa ttaagaagtc
    13081 ttctaaccaa gtaatcgatt ggatatccaa accgttagta ggctcgtcca agagaagaac
    13141 atctggttta ccaaaaagtg ctttggcgag gagaaccttt actttttcac cgttggccaa
    13201 ttcgctcatg ttttggtagt gtaattcttc tggaatgttt aggttttgaa gtagttgaga
    13261 ggcttcactc tctgcttccc aacctccaag ttcggcaaac tctccttcga gttcggcagc
    13321 acgaaccccg tcctcgtctg agaaatcttc cttcatgtag atagcatctt tctctttcat
    13381 gatgctataa agtttttcat ttcccatgat aacgacatca atggcacgtt catcttcgta
    13441 gtcaaagtga ttttgacgaa gaacagagag acgttcatct ggaccaagag agatgtgacc
    13501 agtagtaggt tcgatatctc cagctaaaat ttttaaaaag gttgattttc cggcaccatt
    13561 agcaccgatt aatccgtaag tatttccttc tgtaaatttg atattgacat catcaaaaag
    13621 tttgcgatca ctaaaacgta gtgaaacatc agatactgta agcaatattt ttctcctata
    13681 tgtgtaatat atttattcta ctagaaaata cagaaatatt caaattttta tttgtcaatt
    13741 ttgtgtaaat tatatttaca gtatccttta cacaaatctg taaaaagcaa ggctgattta
    13801 ttttgataaa ttacggttat ttcattaaaa aaatgctata attgaaagga ctatatcgaa
    13861 ggagaacaaa atgactaaac ccattatttt aacaggagac cgtccaacag gaaaattgca
    13921 tattggacat tatgttggaa gtctcaaaaa tcgagtatta ttacaggaag aggataagta
    13981 tgatatgttt gtgttcttgg ctgaccaaca agccttgaca gatcatgcca aagatcctca
    14041 aaccattgta gagtctatcg gaaatgtggc tttggattat cttgcagttg gattggatcc
    14101 aaataagtca actattttta ttcaaagcca gattccagag ttggctgagt tgtctatgta
    14161 ttatatgaat ctagtttcgt tagcacgttt ggagcgaaat ccaacagtca agacagagat
    14221 ttctcagaaa ggatttggag aaagcattcc gacaggattc ttggtctatc caatcgctca
    14281 agcagctgat atcacagctt tcaaggctaa ttatgttcct gttgggacag atcagaaacc
    14341 aatgattgag caaactcgtg aaattgttcg ttcttttaac aatgcatata actgtgatgt
    14401 cttggtagag ccggaaggta tttatccaga aaatgagaga gcagggcgtt tgcctggttt
    14461 agatggaaat gctaaaatgt ctaaatcact aaataatggt atttatttag ctgatgatgc
    14521 ggatactttg cgtaaaaaag taatgagtat gtatacagat ccagatcata tccgcgttga
    14581 ggatccaggt aagattgagg gaaatatggt tttccattat ctagatgttt ttggtcgtcc
    14641 agaagatgct caagaaattg ctgatatgaa agaacgttat caacgaggtg gtcttggtga
    14701 tgtgaagacc aagcgttatc tacttgaaat attagaacgt gaactgggtc ctattcgtga
    14761 gcgccgtatt gaatttgcta aggatatggg agaagtttat aatatgattc aaaaaggtag
    14821 tgaaagagcg cgtgaagttg cgggtcaaac cctatctgag gtaaaagggg caatgggact
    14881 tcattacttt aactaagttt attttacaag aaactatcat ttctatctcg aagaaaagat
    14941 agttttttat ttacccctgt aacatttgac aaatttttat agaatggtat gatagataca
    15001 atataaaaag agtcaagctc aaaaagaaag aaaagaggaa acttcgaatg tctaattggg
    15061 acactaaatt tttgaaaaaa ggttttacct ttgatgatgt attgcttatt ccagctgaaa
    15121 gtcatgtgtt gcctaacgat gcagatttaa caactaaatt ggcagataat ttgactttaa
    15181 atatcccaat tattaccgct gccatggaca cagttacaga gagtcaaatg gccattgcta
    15241 ttgctcgtgc aggtggtctc ggagttatcc ataaaaacat gtcaattgct caacaagcag
    15301 acgaggttcg taaggtaaaa cgttctgaaa atggagttat tattgatccg ttcttcttga
    15361 cgcctgaaca tacaattgct gaagcagatg agcttatggg tcgttaccgc atcagtggtg
    15421 ttccagttgt tgaaacactt gaaaatcgta aattggttgg tattttgaca aaccgagatc
    15481 ttcgttttat ttcagattat aatcaaccaa tttcaaacca tatgactagt gaaaatcttg
    15541 ttactgctcc tgtgggtacg gatcttgcaa cggctgagag tattcttcaa gagcatcgta
    15601 ttgaaaaact tccgttggtt gatgaagaag gcagtctttc tggtttgatc actatcaaag
    15661 atattgaaaa agttattgag tttccaaatg cggctaaaga tgagtttggt cgtcttctag
    15721 ttgcaggtgc agtaggtgtt acttcagata catttgaacg tgcagaggct ctttttgagg
    15781 caggagcgga tgcgattgtt attgatactg cacatggtca ttctgcaggt gtcttgcgta
    15841 aaattgccga gattcgtgct catttcccag atcggacttt gattgctgga aatattgcta
    15901 ctgctgaagg tgcacgtgcc ctttatgaag cgggtgtaga cgttgttaag gttggtattg
    15961 gaccaggttc tatctgtact actcgtgtga ttgctggtgt tggtgttccg caagtaacag
    16021 ctatctacga tgctgcagct gttgcgcgcg aatatggtaa aacgattatt gctgacggtg
    16081 ggatcaagta ttctggagat attgtaaaag cacttgctgc aggtggaaat gctgttatgc
    16141 ttggatctat gtttgctgga actgatgaag ctccaggcga aactgaaatc ttccaaggac
    16201 gtaaattcaa gacttaccgt ggtatgggat caattgctgc tatgaagaaa ggttcaagcg
    16261 accgttattt ccaaggttct gtcaatgaag caaacaagct tgttccagaa ggaattgaag
    16321 gtcgtgttgc ttataaagga gcggcagctg atattgtttt ccaaatgatt ggtggtattc
    16381 gctctggtat gggttactgt ggtgcagcta accttaaaga actacacgat aatgctcaat
    16441 ttattgaaat gtctggtgct ggtttgaaag aaagccatcc tcatgatgtg caaattacta
    16501 atgaggcacc aaattattct atgtaaaaaa caatgaaaag aactccagtg aaaacaggag
    16561 ttcttttaca atgttgtcaa tttccattta cagcagcttt accatcctga atagtgaaga
    16621 tacttagatt ttctggcaga ttttgaagat ggtctaagct tgttgttgtg ataaaggttt
    16681 ggattgattg agaaatcgtt tctaataatt ttaactgtct agtgttgtca agttcactca
    16741 tcacatcgtc aagcagtaat ataggagatt ctgtggtaat gctttccatt aattcgattt
    16801 ctgctaattt tatcgagagg acgagactac gatgttgacc ttggcttccg aaactagcat
    16861 ccatcccatt tatataaaaa gaaatgtcat ctcgatgagg accgacacca gtattctttt
    16921 taaataaatc tctggatcta cttttttcta aagcaatttt gaaagattcg gataagtttt
    16981 gtttgtcagt tatattgaca gaagattgat aggatattga caactcttcg atctgattag
    17041 agagttcaaa atgtttctta cgcccaaatg attctagttt ttttatgaaa tctaagcggt
    17101 gattcattac acgacatcca taatcaacta gctgatcatc taacacagaa aggaatgttt
    17161 catctatttt ttgagctgat tttaggtaag tgtttctttg ctttaggatg tggttataat
    17221 tggttaagtc agataaatag attggcttaa tttgcccaag ttccatatca atgaattttc
    17281 gtcgaatcga aggtgctcct ttaattagtt gtaaatcttc aggagcaaat aagacaacat
    17341 tcatgtgtcc tacataatct gaaaggcgtg cctgttttaa gtgattaact tttgttacac
    17401 ggcctttttg tgttagttcg atttctaggg gaatggatcc agtttttttc tgaacgagac
    17461 ctgaaagatg aagttgttcc tcatcaaaat gaatgagatt tttatctgtt cgagttcgat
    17521 gactacgcgt taaggctaaa aaatagatag cctctaacat gtttgttttt ccttgtgcat
    17581 tacgtcccaa aaagacattc aatttaggat taaagtctat tttcgtttct ttgtaattac
    17641 gaaaagtctt gagagataga tgttgtagcc acatgattat ctaccaggga atcgtggagc
    17701 ttgttggctt ttaggtgatg aagcaggttt cgatttgtct tttttaactc ccttattcat
    17761 ctttttgaca agtttagcga tccgttcttt ttcaacttta tcagcttggt attcatcttg
    17821 ttcttcagaa gtaggttgtg tcaacaagat gtcaatgttc atgtcaggga tgtcaacttt
    17881 atcgccaata cgaagttttt ttccacgacg actctctaat tccctattaa agtaaacaga
    17941 atgttcagag agaaatgatt taatagctcc tccgctatgt gtaattccaa gttctttgag
    18001 tagtgcttgg agggtaataa attcttcaaa taatttgtat tccataattc acctcaatct
    18061 ttggtattat accatatttt cctaaaaata gtgagagaga cagcgagaaa tgtaagcgat
    18121 ttttatttca aaagtgttac agggaacaag aaaatttcag gttttcgtga tataatagaa
    18181 gtctgtatat aaggaggtaa atcatggagt tagtgcatgg aatttcaaca cattttatcc
    18241 aatcaaaaaa gtttaaaaca aacaaaatta ccgtgcgttt taccgctcca ttatcccttg
    18301 atacgattgc aggtcacatg ttgagtgcaa gtatgctaga gactgctaat cagatgtacc
    18361 ccacttctca agatttgagg agacacttgg ccagtctata cggtacagat atgtcaacca
    18421 attgtttcag aagagggcaa agccacatta tagaattgac atttacctat gttcgtgatg
    18481 agtttttaag taggaaaaac gtgctaacct ctcagatttt ggaacttgta aaagaaactc
    18541 ttttttcacc cgtagtagtt gataatgggt ttgatccggc cttatttgaa attgagaaaa
    18601 aacaattgct agcaagttta gcagctgata tggatgattc tttttatttt gcacataaag
    18661 aattggataa attgtttttt catgatgaac gtcttcaatt ggaatatagt gatttacgaa
    18721 atcgtatttt agctgaaact ccacaaagtt cttattcttg tttccaagaa tttttagcca
    18781 atgatcgaat agatttcttt ttcctaggtg attttaatga ggttgaaatt caaaatgtat
    18841 tagaatcatt tggctttaaa ggtcgaaaag gagatgtgaa ggttcagtat tgtcaacctt
    18901 attctaatat ccttcaggaa ggtatggttc ggaaaaatgt gggacaatct attttggaat
    18961 taggttatca ttacccttct aaatatggtg atgagcaaca tttacccatg attgtaatga
    19021 atggtttact tggtggattt gctcactcta agctctttac aaatgtccgt gaaaatgctg
    19081 gattagctta taccatttca agtgagcttg atttatttag tggattcttg aggatgtatg
    19141 ctggtatcaa tcgagaaaat cgtaaccagg ctcgtaaaat gatgaataat caactgcttg
    19201 atttaaaaaa aggttatttt acagagtttg agttaaatca gaccaaggaa atgattcgtt
    19261 ggtcgttgtt actttctcaa gataatcaat cttcattgat tgaacgtgct tatcaaaatg
    19321 ccttatttgg aaaatcttca gcagacttta aaagttggat tgcaaagctt gaacagattg
    19381 acaaagatgc tatttgtaga gtagctaata atgtgaaact acaagcgatt tactttatgg
    19441 aaggaataga atgacaaagg ttgtttttga agaaaaatac tatccagctg taaaagaaaa
    19501 ggtttatcga actcgtttgg ccaacggatt gacagttgct cttttgccta aaaaggaatt
    19561 taaagaggtt tacgggagtg taactgtaca gtttggttcg atagatacgc ttgtcacaga
    19621 agttgacgga gatgtaaaac aatatcctgg aggaattgct cattttcttg aacataaatt
    19681 atttgagaga gaagattcta gtgatttgat gtcggctttt acgagtctag gtgcagatag
    19741 taatgccttt acaagcttta caaaaacaaa ctatcttttt tcagcaacgg attatttttt
    19801 agaaaattta tatttacttg atgaattggt aacatcagca cactttactg aagcttccat
    19861 tctgacagag caggatatta ttcagcaaga acgagaaatg taccaagatg atccagattc
    19921 gtgtttattc ttttcaactt tagcgaattt gtatcctggt acacctttag caactgatat
    19981 agttggaagt gaggagtcca tttcccaaat caatttaact aatttgcaag aaaattttac
    20041 aaagttttac aaacctgtaa acatgtctct gtttttagtt ggtaattttg atgtggagcg
    20101 agtacaggac tattttgaaa gcaaagaact gaaagattca gattttcagg aagtagcaag
    20161 agaaaagttg tttttacagc ctgtaaagcc aacagatagt atgagaatgg aagtatcttc
    20221 tcccaaacta gcgattggag ttagaggtaa gcgagaagtt tctgaagcgg attgctatcg
    20281 acatcatatt ttattaaaat tattgtttgc aatgatgttt ggttggactt cggatcgttt
    20341 tcaaaaatgt tatgaatcag gtaaaattga tgcgtcctta tctctggaag ttgaaataac
    20401 aagtcgcttt cattttgtca tgttgacaat ggatacgaaa gagccagttg ctttgtctca
    20461 tcaatttagg aaggctattc gtaattttac aaaggattta gatattacag aggaacattt
    20521 agatattatc aaaagagaga tgtttggcga atttttcagt agcatgaact ctcttgaatt
    20581 tattgcaacg caatatgatg cttttgaaaa tggtgagaca atttttgatt tgccgaaaat
    20641 tttacaggaa attactttag aggatgtcct tgatgctgga catcatttaa tagatgatgg
    20701 tgacatagtt gattttacaa tattcccatc gtagtaacct atcataatag acactagaaa
    20761 gaagggatga caagtatgag aaaaaaaaca attggagagg ttttacgatt agctagaatc
    20821 aatcagggat tgagtttaga tgaattgcag aaaaagacag aaatccagtt agatatgttg
    20881 gaagcaatgg aagcagacga tttcgatcaa cttccaagtc ctttttacac gcgttctttc
    20941 ttgaaaaaat atgcatgggc tgttgagtta gatgaccaaa ttgttttgga tgcttatgat
    21001 tctgggagta tgattactta tgaggaagta gatgttgatg aagatgagtt gacaggtcgt
    21061 agacgttcaa gtaagaaaaa gaagaaaaaa acatcatttt tacctttatt ttattttatc
    21121 ctttttgctt tatcgatttt aatttttgtg acttattatg tttggaacta tattcaaact
    21181 caaccagagg agccttctct ttctaattac agtgtggttc aatcaacaag ttcaactagc
    21241 tctgttcccc actcctcaag tagtagttct tctagtatag aatcagctat aagtgtatca
    21301 ggcgaaggaa atcatgtaga aatcgcttat aagacaagta aggaaacagt taaattgcaa
    21361 ttggcagttt cagatgttac aagttgggtc agtgtttcag aaagcgaact tgagggcggt
    21421 gtaaccttat cgccaaagaa gaaaagtgca gaagcaacag ttgcaactaa aagtcctgta
    21481 acaattacgt taggtgttgt aaaaggtgtt actttgacag tagataatca gactgttgat
    21541 ttatcgaaat taacagctca gactggacaa atcactgtaa cctttactaa aaattaagga
    21601 aaaacgaatg aaaaaagaac aaattcccaa tctcttaaca ataggtcgaa ttctctttat
    21661 acctattttt atctttattt taacgatagg aaattcgata gagagtcata tagttgcagc
    21721 tattatcttt gctgttgcca gtattaccga ctatttagat ggatatttag ctcgtaaatg
    21781 gaatgtggtc agtaattttg gtaaatttgc agatcctatg gcggataagt tactagttat
    21841 gtcggctttt attatgttga ttgagttagg tatggctccg gcttggattg ttgcagtgat
    21901 tatctgtcgt gagttagctg tgacaggttt aaggctttta ttggttgaaa ctggtggaac
    21961 aattttagca tcagcaatgc ctggaaaaat taaaactttt agtcagatgt ttgctattat
    22021 tttcttgcta ttacattgga ctttgcttgg tcaagttcta ctttatgtag ccttattttt
    22081 cactatctac tctggctatg actatttcaa gggtagtgcc tatgtattta aagggacatt
    22141 tggttcgaaa tgaaatcaat aattgatgta aaaaatcttt cttttcgcta taaagaaaat
    22201 cagaactact acgatgtgaa ggatattacg tttcacgtga aacgtggaga atggctttcg
    22261 attgtagggc ataatggtag tggtaaatca actacggttc gattaattga tggcttactg
    22321 gaagcagaat ccggagagat tgtaattgat ggccaacgtt tgactgagga aaatgtttgg
    22381 aatatacgtc gtcaaatcgg tatggttttt caaaatccag acaatcaatt tgttggagcg
    22441 actgttgaag atgatgttgc ttttggtttg gaaaatcagg gactttctcg tcaagaaatg
    22501 aaaaagagag tggaagaagc tctggcttta gttggcatgt tggactttaa aaagagagag
    22561 ccagcgcgtc tatcaggtgg ccaaaagcaa cgtgtggcca ttgcaggtgt tgtagcccta
    22621 agaccagcta ttttaatctt agatgaagca acgagtatgt tggatcctga ggggcgtaga
    22681 gaacttattg ggacagtaaa aggaattcga aaagactatg atatgacggt catttctatt
    22741 acccatgatt tggaagaagt cgccatgagt gatcgcgtat tggtcatgaa aaaaggggaa
    22801 attgaatcaa ctagtagtcc aagggagctt ttctctcgaa atgatttaga tcaaattgga
    22861 ttagacgatc cttttgctaa tcaattaaaa aaatctttga gccagaatgg ctatgattta
    22921 cctgaaaatt atttgacaga aagtgagcta gaggataagc tatgggaatt gctctagaaa
    22981 atgtgaattt tacatatcaa gaaggtactc ccttagcttc agcagctttg tcggatgttt
    23041 ctttgacgat tgaagatggc tcttatacag ctttaattgg gcacacaggt agtggtaaat
    23101 caactatttt acaactctta aatggtttat tggtgccaag tcaagggagt gtgagggttt
    23161 ttgatacctt aatcacctcg acttctaaaa ataaagatat tcgtcaaatt agaaaacagg
    23221 ttggcttggt atttcagttt gctgaaaatc agatttttga agaaacggtt ttgaaggacg
    23281 ttgcttttgg accgcaaaat tttggagttt ctgaagaaga tgctgtgaag actgcgcgtg
    23341 agaaactggc tctggttgga attgatgaat cactttttga tcgtagtccg tttgagctgt
    23401 cagggggaca aatgagacgt gttgccattg caggcatact tgccatggag ccagctatat
    23461 tagtcttaga tgagccaaca gctggtctag atcctctagg gagaaaagag ttgatgaccc
    23521 tgttcaaaaa actccaccag tcagggatga ccatcgtctt ggtaacgcat ttgatggatg
    23581 atgttgctga atatgcaaat caagtctatg taatggaaaa gggacgttta gtaaaggggg
    23641 gcaaaccaag tgatgtcttt caagacgttg tttttatgga agaagttcag ttgggagtac
    23701 ctaaaattac ggccttttgt aaacgattgg ctgatagagg cgtgtcattt aaacgattac
    23761 cgattaagat agaggagttc aaggagtcgc taaatggata gtatgatttt ggggcgttat
    23821 atcccagggg attcgattgt tcaccgattg gatccacgta gcaaattgct tgctatgatg
    23881 ctactgattt tgattgtgtt ttgggctaat aaccccttga cgaatctgat tctttttata
    23941 gcgacaggga tatttattgc cttgtcagga gtatctcttt cattttttat tcagggcttg
    24001 aagtctatgt ttttcttgat tgccttcaca actatttttc aactattttt catttctaat
    24061 gggaatgttt tatttgagtt ttcgtttgtg agaatcacgg attatgcttt gcaacaagct
    24121 gggattattt tttgtcgctt tgtattgatt attttctttt caactttgtt aaccttaaca
    24181 accatgcctt taagtttggc atcagctgtc gaagctttat tagcaccttt aaagcgtgtg
    24241 aaagttccag ttcatgaaat tggattgatg ctgtctatga gtttgcgttt tgtcccaacc
    24301 ttgatggatg atacgacgcg gattatgaat gcacagaaag ctcgtggagt ggattttgga
    24361 gaaggaagta tcgttcaaaa agtaaaggcg atgattccca ttttgattcc tctttttgcg
    24421 acaagtttaa aacgtgcaga ttccttggct atcgctatgg aagcgcgtgg ctatcagggt
    24481 ggaaaaggca gaagtcaata ccgacaattg aaatggactc taaaggatac gctgaccatt
    24541 cttgttattc tcgtacttgg ttgttgttta tttttcttaa aatcttagta gctttcagga
    24601 attgataaaa agttactgta acagtttttg atataaaggt agggatatga accgttttaa
    24661 aaaatcaaaa tatgtcatta ttgtttttgt cactgttctg cttgtgtcag ctctcttagc
    24721 gacgacttat tcaagtacaa ttgtgacaaa attaggagat ggaatctcat tggttgatag
    24781 agttgtacaa aaaccttttc agtggtttga ttctgtcaaa tcagatttgg ctcatttgac
    24841 acgaacatat aatgaaaatg aaagtttgaa gaaacagctt taccaattag aagttaaatc
    24901 aaatgaggtg gaaagtttaa agacagaaaa tgaacaactg cgccaattgc ttgatatgaa
    24961 gtctaaattg caagccacaa agactttagc agcagatgtt attatgcgtt ctccggtatc
    25021 ttggaagcag gagttgacct tagatgcagg tagatcaaaa ggtgcttctg agaacatgtt
    25081 agctattgca aatggtggct tgattgggag tgtttcaaaa gtagaggaga actctactat
    25141 agtcaacctt ctgacaaata cggaaaatgc tgataagatt tctgttaaaa ttcaacatgg
    25201 ctctactaca atttatggaa ttattattgg ctatgacaag gaaaatgacg ttcttaaaat
    25261 tagccaatta aatagtaata gcgatattag tgcgggagat aaggtgacta ctggtggatt
    25321 aggaaacttt aacgttgctg atattcctgt tggtgaagtg gttgccacaa cgcatagtac
    25381 agactatttg acacgagaag taactgttaa attgagtgca gatactcata atgtagatgt
    25441 gatagaatta gtggggaatt cataatgaga cagttgaagc gagttggagt atttttattg
    25501 cttcctttct ttgttctaat tgacgcccat attagccagc ttctgggctc atttttcccc
    25561 catgtacatt tggctagtca ttttcttttt ctatttctct tatttgagac gatagaagta
    25621 tcagagtatc tctacctagt ctattgtttt gttataggct tggtttatga tgtttacttt
    25681 ttccatctaa tagggattac aactctctta tttatcttat tgggagcctt ccttcataaa
    25741 ttgaatagtg ttattttgtt gaatcgttgg acaagaatgc tagctatgat tgtgctgaca
    25801 ttcctgtttg aaatgggtag ttatcttttg gcttttatgg tagggttgac agtagatagc
    25861 atgtcgattt ttatagtcta tagcttggta ccgacgatga ttttaaattt tttatggatt
    25921 actgtttttc aatttatttt tgaaaaatat tatctataag aacgacatat aaatgtaaca
    25981 aaggcgtaat atttattagg cctttttttg gtatactagt attgtcttta aaagaaggag
    26041 tatctacgta atatgaagaa aaaaatctta gcgtcacttt tattaagtac agtaatggtt
    26101 tctcaagtag ctgttttaac aactgcgcat gcagaaacga ctgatgacaa aattgctgct
    26161 caagataata aaattagtaa cttaacagca caacaacaag aagcccaaaa acaagttgac
    26221 caaattcagg agcaagtatc agctattcaa gctgagcagt ctaacttgca agctgaaaat
    26281 gatagattac aagcagaatc taagaaactc gagggtgaga ttacagaact ttctaaaaac
    26341 attgtttctc gtaaccaatc gttggaaaaa caagctcgta gtgctcaaac aaatggagcc
    26401 gtaactagct atatcaatac cattgtaaac tcaaaatcaa ttacagaagc tatttcacgt
    26461 gttgctgcaa tgagtgaaat cgtatctgca aacaacaaaa tgttagaaca acaaaaggca
    26521 gataaaaaag ctatttctga aaaacaagta gcaaataatg atgctatcaa tactgtaatt
    26581 gctaatcaac aaaaattggc tgatgatgct caagcattga ctacgaaaca ggcagaacta
    26641 aaagctgctg aattaagtct tgctgctgag aaagcgacag ctgaagggga aaaagcaagt
    26701 ctattagagc aaaaagcagc agctgaggca gaggctcgtg cagctgcggt agcagaagca
    26761 gcttataaag aaaaacgagc tagccaacaa caatcagtac ttgcttcagc aaacactaac
    26821 ttaacagctc aagtgcaagc agtatctgaa tctgcagcag cacctgtccg tgcaaaagtt
    26881 cgtccaacat acagtacaaa cgcttcaagt tatccaattg gagaatgtac atggggagta
    26941 aaaacattgg caccttgggc tggagactac tggggtaatg gagcacagtg ggctacaagt
    27001 gcagcagcag caggtttccg tacaggttca acacctcaag ttggagcaat tgcatgttgg
    27061 aatgatggtg gatatggtca cgtagcggtt gttacagctg ttgaatcaac aacacgtatc
    27121 caagtatcag aatcaaatta tgcaggtaat cgtacaattg gaaatcaccg tggatggttc
    27181 aatccaacaa caacttctga aggttttgtt acatatattt atgcagatta atttacagag
    27241 ggactcgaat agagccctct tttcaggttt taccgtgaca atccctatta aaaattatat
    27301 caaaatagct tgaaaatatt ggaaaagtat ggtagaatga aaattgtcgt gtgaacgata
    27361 atactcattc ttgatgaatt gtgaagcagt tgcccttggg tcgttttgcg agttgaagtc
    27421 aagaagagga aaaaaacaaa aaggagaaat actcatggca gtaatttcaa tgaaacaact
    27481 tcttgaggct ggtgtacact ttggtcacca aactcgtcgc tggaatccta agatggctaa
    27541 gtacatcttt actgaacgta acggaatcca cgttatcgac ttgcaacaaa ctgtaaaata
    27601 cgctgaccaa gcatacgact tcatgcgtga tgcagcagct aacgatgcag ttgtattgtt
    27661 cgttggtact aagaaacaag cagctgatgc agttgctgaa gaagcagtac gttcaggtca
    27721 atacttcatc aaccaccgtt ggttgggtgg aactcttaca aactggggaa caatccaaaa
    27781 acgtatcgct cgtttgaaag aaattaaacg tatggaagaa gctggaactt tcgaagttct
    27841 tcctaagaaa gaagttgcac ttcttaacaa acaacgtgcg cgtcttgaaa aattcttggg
    27901 cggtatcgaa gatatgcctc gtatcccaga tgtgatgtac gtagttgacc cacataaaga
    27961 gcaaatcgct gttaaagaag ctaaaaaatt gggaatccca gttgtagcga tggttgacac
    28021 caatactgat ccagatgata tcgatgtaat catcccagct aacgatgacg ctatccgtgc
    28081 tgttaaattg atcacagcta aattggctga cgctattatc gaaggacgtc aaggtgagga
    28141 tgcagtagca gttgaagcag aatttgcagc ttcagaaact caagcagatt caattgaaga
    28201 aatcgttgaa gttgtagaag gtgacaacgc ttaatttata caaatagtaa ttacctagga
    28261 gggcggggct tagcccggct ctcctatttt caaaaaatat aggagaatta aaatggcaga
    28321 aattacagct aaacttgtaa aagagttgcg tgaaaaatct ggtgccggtg ttatggacgc
    28381 taaaaaagcg cttgtagaaa cagacggtga catcgaaaaa gcgattgaat tgcttcgtga
    28441 aaaaggtatg gctaaggcag ctaagaaagc tgaccgtgtt gctgcagaag gtttgactgg
    28501 tgtttatgtt aacggtaatg ttgcagcagt tattgaagta aacgctgaaa ctgacttcgt
    28561 tgcaaaaaac gctcaattcg ttgaattggt aaatactaca gctaaagtca ttgctgaagg
    28621 aaaacctgct aacaatgaag aagctcttgc tttgataatg ccttcaggtg aaactcttga
    28681 agctgcatac gtatctgcaa cagcaactat cggagagaaa atctcattcc gtcgctttgc
    28741 attgattgaa aaaacagacg cacaacactt tggagcatac caacataacg gtggacgtat
    28801 cggtgttatt tcagttgttg aaggtggaga cgaagcactt gctaaacaat tgtcaatgca
    28861 catcgcagcg atgaaaccaa cagttctttc ttacaaagaa ttggatgagc aattcgttaa
    28921 agatgagttg gcacaattga atcacgttat cgaccaagac aacgaaagcc gtgcaatggt
    28981 taataaacca gctcttccac acttgaagta tggatcaaaa gctcaattaa ctgatgatgt
    29041 tattgctcaa gctgaagctg acatcaaagc tgaattggct gcagaaggca aaccagaaaa
    29101 aatctgggac aaaattattc caggtaaaat ggatcgcttc atgcttgata acactaaagt
    29161 tgaccaagct tacacacttc ttgcacaagt ttacatcatg gatgacagca agacagttga
    29221 agcatacctt gaatcagtta acgcttcggt agttgagttt gctcgctttg aagttggtga
    29281 aggtatcgag aaagctgcaa acgacttcga agctgaagtt gcagctacaa tggcagcagc
    29341 cttgaataac taataataga aaggaagcaa attgcttcct tttttgtata gggcttagat
    29401 ttttcctgaa attgtttttt ccccagtctc actcgattag aataattaaa acaaaaagcc
    29461 ctataataag ggctaagtgc atttaggaga ctatacttca aattcatagt aagcgcgtca
    29521 taacaaggta tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatcg
    29581 gaggaaaggt attgtactat gataattcaa ctaagtgatt taggtcaagt tcaccttgtt
    29641 tgtggcaaga cagatatgag g
//
LOCUS       DAVMBH010000024        28093 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVMBH010000024 DAVMBH010000000
VERSION     DAVMBH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.024"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1..1090
                     /locus_tag="VYP30_001192"
                     /pseudo
     CDS             1..1090
                     /locus_tag="VYP30_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1379..1849)
                     /locus_tag="VYP30_001193"
     CDS             complement(1379..1849)
                     /locus_tag="VYP30_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1808192.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(1815..2621)
                     /locus_tag="VYP30_001194"
     CDS             complement(1815..2621)
                     /locus_tag="VYP30_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1808193.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(2827..3468)
                     /locus_tag="VYP30_001195"
     CDS             complement(2827..3468)
                     /locus_tag="VYP30_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808194.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(3465..5573)
                     /locus_tag="VYP30_001196"
     CDS             complement(3465..5573)
                     /locus_tag="VYP30_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1808195.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPNTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(5625..5912)
                     /locus_tag="VYP30_001197"
     CDS             complement(5625..5912)
                     /locus_tag="VYP30_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1808196.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPDAWARASLTKIPPTGMEYFYGFE"
     gene            6343..6663
                     /locus_tag="VYP30_001198"
     CDS             6343..6663
                     /locus_tag="VYP30_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1808197.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(6715..7302)
                     /locus_tag="VYP30_001199"
     CDS             complement(6715..7302)
                     /locus_tag="VYP30_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1808198.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            7544..8215
                     /gene="sdaAB"
                     /locus_tag="VYP30_001200"
     CDS             7544..8215
                     /gene="sdaAB"
                     /locus_tag="VYP30_001200"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1808199.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            8224..9096
                     /gene="sdaAA"
                     /locus_tag="VYP30_001201"
     CDS             8224..9096
                     /gene="sdaAA"
                     /locus_tag="VYP30_001201"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1808200.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9118..9750
                     /locus_tag="VYP30_001202"
     CDS             9118..9750
                     /locus_tag="VYP30_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1808201.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLVPQQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            9776..9874
                     /locus_tag="VYP30_001203"
                     /pseudo
     CDS             9776..9874
                     /locus_tag="VYP30_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10055..11905)
                     /locus_tag="VYP30_001204"
     CDS             complement(10055..11905)
                     /locus_tag="VYP30_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1808202.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(11944..13104)
                     /locus_tag="VYP30_001205"
     CDS             complement(11944..13104)
                     /locus_tag="VYP30_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1808203.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNMLQ"
     gene            13162..14328
                     /locus_tag="VYP30_001206"
     CDS             13162..14328
                     /locus_tag="VYP30_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1808204.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     IGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14468..14794
                     /locus_tag="VYP30_001207"
     CDS             14468..14794
                     /locus_tag="VYP30_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1808205.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            14781..15374
                     /locus_tag="VYP30_001208"
     CDS             14781..15374
                     /locus_tag="VYP30_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1808206.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGIEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            15367..16278
                     /locus_tag="VYP30_001209"
     CDS             15367..16278
                     /locus_tag="VYP30_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1808207.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQYDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            16340..17404
                     /locus_tag="VYP30_001210"
     CDS             16340..17404
                     /locus_tag="VYP30_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808208.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPYQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(17476..18336)
                     /locus_tag="VYP30_001211"
     CDS             complement(17476..18336)
                     /locus_tag="VYP30_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1808209.1"
                     /translation="MAKTFFIPNKQSILGEQEILTAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(18458..19444)
                     /locus_tag="VYP30_001212"
     CDS             complement(18458..19444)
                     /locus_tag="VYP30_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1808210.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(19716..21191)
                     /locus_tag="VYP30_001213"
     CDS             complement(19716..21191)
                     /locus_tag="VYP30_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1808211.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPVDYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(21449..22372)
                     /locus_tag="VYP30_001214"
     CDS             complement(21449..22372)
                     /locus_tag="VYP30_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1808212.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(22386..23315)
                     /locus_tag="VYP30_001215"
     CDS             complement(22386..23315)
                     /locus_tag="VYP30_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1808213.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(23634..23984)
                     /locus_tag="VYP30_001216"
     CDS             complement(23634..23984)
                     /locus_tag="VYP30_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808214.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(24410..24565)
                     /locus_tag="VYP30_001217"
                     /pseudo
     CDS             complement(24410..24565)
                     /locus_tag="VYP30_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(24750..25361)
                     /gene="rpsD"
                     /locus_tag="VYP30_001218"
     CDS             complement(24750..25361)
                     /gene="rpsD"
                     /locus_tag="VYP30_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1808215.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(25556..26608)
                     /locus_tag="VYP30_001219"
     CDS             complement(25556..26608)
                     /locus_tag="VYP30_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1808216.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(26605..27303)
                     /locus_tag="VYP30_001220"
     CDS             complement(26605..27303)
                     /locus_tag="VYP30_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808217.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(27470..>28093)
                     /locus_tag="VYP30_001221"
     CDS             complement(27470..>28093)
                     /locus_tag="VYP30_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV1808218.1"
                     /translation="MLTRLLLKASDKAPWSDNGEAKNPALSPLGENVKTKGQYFYQVA
                     LDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKE
                     TSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMS
                     DTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT         8377 a         6076 c         5122 g         8518 t
ORIGIN      
        1 ttcaagtgct atcattgttc taaaattatg gttgctgaaa cttctatcgt caagaagaat
       61 catcaaatcc ctcgtatcat caaccaaaag attgctcaaa agttaattga aaagatttct
      121 atgactgata ttgcccatca gctttccatc tcaacttcaa ctgtcattcg aaagctcaat
      181 gattttcact ttaaacatga tttttcttgt cttcctgaga ttatgtcctg ggacgttgaa
      241 acagtccgag gagtgactgt ttcaatcggg agatggagat gagcttcatt gcgcaagatt
      301 ttaacaatct taatattatc actgttcttg aaggcagaac acaagctgtc atccgaaatc
      361 actttcttcg ctacgataga gccgttcgtt gtcaagtgaa aatcattacg atggatatgt
      421 ttagtcctta ctatgacttg gctaaacagc ttcgctttca aatttctagg ctcaggctga
      481 aacagtctcc cagactgttt cactcccgaa tgctaaaatc gttcttgatc gctttcacat
      541 tgtacaacat cttagccgtg ctatgagtcg tgtgcatgtc caaatcatga atcagtttca
      601 tcgaaaatcc catgaataca aggctatcaa gcgctactgg aaactcattc aacaggatag
      661 ctgtaaactg agtgataagc gattttatcg tcctattttt cgtatgcact taaccaataa
      721 agagatttta aacaagcttt tgagctattc ggaagacttg aaacaccact atcaactcta
      781 tcagctcttg ctttttcact tccagaataa ggaaccagag aaatttttcg gacttattga
      841 ggacaatctt aagcaggttc atcctatttt tcagactgtc tttaaaacct tcctcaaaga
      901 taaagaaaag attatcaacg cccttcaact acactattct aatgccaaac tggaagcgac
      961 caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcgaaact ttgaaaactt
     1021 caaaaaacgg atttttatcg ctttgaacat caaaaaagaa aggacgaaat ttgtcctttc
     1081 tcgagcttag ctgacttcaa cccactacag ttgacaaaga gccttatttg ttcgttagtt
     1141 cttaatacca gccattgtta aaccagaagt ttttagctct gccaagccac atagtgtgtt
     1201 tactactatg tgtccatgtc accatgaatc gccgaacgat ttaacgagaa agtatgactt
     1261 ttacgtttat cccaactcaa ttatgacatt tttttcaaaa gtcaatatat ctcacttttt
     1321 caacgacaag aaagaggcta ccaatcgacc aacctcttat tctgaaccca tcactccatc
     1381 actttttagc ttcattcgct ttcttagcga ctgcaatctg gtattcgact tggtcattcc
     1441 ccttaccggt acaaccatga gcaattgtag tcgctcctat ctgatgcgct atttcaacca
     1501 attttttaga aatcagaggg cggctcaagg cagataccaa gggatacttt tgttcataat
     1561 aggcatgtga ctgatgagcc actagcacat aatctgtagc aaattcgtcc ttaacatcaa
     1621 tgacataaga ttctactgcc ccaaccttaa gagccttatc atggatgaaa tctaagtctt
     1681 tcccttcacc cacatccata caaactgaaa caacatcata gtctttcttt aaccaggtaa
     1741 tagcaactga tgtgtccaaa ccgccagaat aggccaaaat tactttttct ttactcatgt
     1801 tcttttcctt ctttctattt ttcaatggat gctttaaagg catcctcaat gagtttgtct
     1861 aattccccag actccttcaa cttttgaatg gttttatcga ctgcctcttt caattccttg
     1921 ctatcttttt tcatggctac cgcataggaa tcatcttgct ctttttcaaa attgaggtct
     1981 gcgattgcta aatcaggatt attttccaca aatcccttgg caacgggttc ttcaaaaata
     2041 acggcatcca cttgccctga ttttaaatct gtgattaaat tcccattttt aggcagagat
     2101 acgagggaag aattttgtag caaatctttc gccatcgtct cttgaatcga acctttctgc
     2161 gctccgacct ttttctgcgc caaatcgttg acagactgat aagtggctaa atcagatttt
     2221 ttgacaatga gtttattttt tgcagtatag tagggagttg aaaaatcaaa caccttgctc
     2281 cgttcatctg tcttagaaac acctgatatg gcaaggtcag cttttcctga ttgaacgcta
     2341 gccagtacat tgtcaaaact cataggagat agttccaatt cgacacctag ttctgttgcg
     2401 atagccttgg ctaattcgat atctgaaccc acaatctgat ttttcccatc aaccactttt
     2461 tgatattcaa atggagcaaa atctggattg agggctacaa ccaattttcc tttggacttg
     2521 atggcttcaa ttccagccga ttgattgtta ctacaagcaa atagtagggg gagcatcact
     2581 aaaccaaaca tcgtcatcaa caccttcttc atcttattca taacaaagcc tcctttatgt
     2641 ttattctttt ttattgtata aataatactc ctatactcat cctttgtcaa gcctaaattg
     2701 aaaaaatttt caatttgaaa caaaaaaacc tagaaatact acataaaatg tcattcctag
     2761 gcgtatttat gctatttttc tctagaaaac atgagtattc agccagtcaa aaggagctga
     2821 atgaactcat tttccctcgc ccaattcaat gacacgatga cattgttggg ctacataagc
     2881 atcgtgggtc acaataatga ctgttttccc ttctcgattc atctctaaga gaaacttcaa
     2941 gaccaaatct ctattttcag gatccagcga acctgtaggt tcatcggcta aaatcagctg
     3001 gctgggtttt aagatggctc tagcaactgc aattcgttgt tgttcgcccc cagacaactc
     3061 ggagaccctt tgatgcaaag tagctgacaa acctactctc tctaaaatct cttccacctt
     3121 tttgagtttg tctttcttag gcaatttcac atatttcagc gccagcatga gattgtactc
     3181 gaccgtttca tcatcaatca gggcaaaatt ttgaaacaga taagagatat gttcacggat
     3241 tattgtttgc gacttagcag aattaaccgc tagatttgtc tgaccaaaaa tctcataccg
     3301 tccgctataa tcaccatcta tcaaacccaa taaatttaac aaggtcgact tcccactacc
     3361 actcttacca acaatagcta ccaaatcccc ctgatcaatc ctgagagata agttatccaa
     3421 aatcactttt cccccaatgg ttttggtaat atttttcaac tcaatcataa gatgccccct
     3481 ttcaataact ctactagact tcttttctcc atcctagaag ctaagcctag cacaaatagt
     3541 atatccagac atgtaaaacc tgcaaacagt agaagtggta agaacgcatg ggcaaagaaa
     3601 atcaagacta gaagagggaa actatagccc agcaagagca gaacgaggag aggacggtag
     3661 cgatcgacca gtttccaccc cataaacttc ttggtaatga tatccctgcg cttcaataag
     3721 aaagttgtta ctagtaagaa gtaggaaatc atcatgctaa ggagaccaaa caaagcaaag
     3781 agtaggttaa aattccgaac agcatctcga taagaatcca ctttctcttg ttgaatggct
     3841 tgaatagatg aaaattttaa ataatttcca tctgacaatt tctcaactaa ctctgtaatc
     3901 tctttttgat gttgaaccgt attttcaatt ttaatcggat tatttaagcc agttgttgac
     3961 agggaggctt tctcatccca catcatatca gaatcattga ccaagctaat aattggattg
     4021 gagagatttt cctttcgctt atcactatat gggaaaaatg accaatctcc ttcataatag
     4081 gcaatctcga catccatctc ctctatcgtt cgtttttgct gctcttcata cttcatcgaa
     4141 tgaaaggcaa ttaacttccc caagagctga tttttatctt cttcaccttt cgtacttgct
     4201 ggcatcaaaa taactttttt aataccggta tttggtagct tgaatccctt gctctttaga
     4261 aaattgcgat tggcatagta aacatccacc gtatctgtta actgatattg ctgaatctgt
     4321 tctgattgga caaaattttt tacaggaaga ctgctactct gcacatagcc cgcctgcgtt
     4381 ttttctacca aatcctgata aaatcgatag aaataatctg tagatttccc tgaccctgct
     4441 agctcttctt gccacagatt atcattgagt ttgaaggttt ctaaggtcag gtaattacct
     4501 tgacttaccc actgttgctg ataagcaagt tctttgtttt cttgttctaa acttctgccc
     4561 accccaatca gtaaggccgt cagtaaaata gttgtcccta ttttcatcac ataattgaag
     4621 ataagaccaa atttgaaaga tgaaaaacct ttcagcagag agctgattgt cattttttgg
     4681 attaagaggt aagtcaacca actgataaag agataaagct gcaacagcaa aaaatgagac
     4741 aaccacagca taggaaacaa atcttttggc ttataatcaa gcaagaaaaa cacgcctaga
     4801 ttgatcacaa gagccccacc taggaggagg taaaggttgc cttttacaac atcagctaaa
     4861 acagccctat cttgaaaacc aagtaatttt tgtaccccaa ctcttttcat ctccatcatc
     4921 ggttgataca ctgtcactaa cacaagaagc aaaatagcca agacaaaaac aatggcagat
     4981 aaaagcaaat ctcgatttat gacttccact gcacttttgt aggtcggctc tagcaaggta
     5041 gcctggtcta tcttgaaaaa atcgctccat ttctgtacaa tcctatcctt gtccatctct
     5101 tgtgtagaag ttatcgtata gcgaccattt aaactacgag atgtatcctt gatataggtt
     5161 tgaaaagtca taagctgaat aggtttggct tttagaaagg tcggaatcgt accaagttta
     5221 ttggaaattt ctttattact atagactcct tcaccatctg tggtaaaatc aagagaagaa
     5281 atcccaaact cttggtaggg gaaggtatct ttatcaaaaa caccagactt gaccacctca
     5341 tcaccactgt ctgttttgat gatggagact ttatactcct ttgatacatc ctcaaaaaat
     5401 cgaagaacag acgctgcagg ttcgttaata tctttcaaat acaaatccaa agaatctaca
     5461 gtctttccca tttcttgaat ccgaaccact tctcgtgtat agtttacatt aaaaacaaaa
     5521 aaagtggtac acagaagcag gagtaacata cagaaattac tgattttttt cataaaagtg
     5581 cctccactac agttttccct ctccaaatag gagagggaag aattttactc aaatccatag
     5641 aaatattcca ttcctgttgg cggaatcttg gtgagggaag ctctagccca tgcatcaggt
     5701 tttgcataat ccttagaggt tctaccccca tgtctaacag ttgctgtatg atatcgagta
     5761 gaatgtaagt aatcagaata tccaaaagtt cctgtccaac ctactccata gttccattga
     5821 ccaccctcaa cccatactgc taaagcattt gtagtagcaa gtataccaca taccattaaa
     5881 gatgcaacac caattttaac taattttctc atgatttatt tctcctatta tcgagagctg
     5941 ttccgtaaaa acagctatag taatttatca acaagtatcg tagtccattg gactcacctt
     6001 ccttctatct catttcattt tttaacaacg aacttactct taaccgggag aatggtgcgc
     6061 ttctgtatca ggtccttgaa caaccagagt agtattaagc aaactctaac tattactcaa
     6121 gaatcagtcc aataaacaat atggatagcg ctttcaaatt tttaaactcc tatcccgtcc
     6181 ttttatctat ataataagca taagcgaaaa tataataact gtcaagtatc tgaagtgaat
     6241 tttataaaaa aattacaagc caaatttgta aagtttacac taagccgcta gggcaatcgt
     6301 ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc
     6361 tataaaaact atcaacgttt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
     6421 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag
     6481 gacgccaaga ataagaaaag ctacgatagg ctggctatct gctatgtccg tattgggatt
     6541 tgtacagata atgctaaact tatccaaaaa gggttctccc ttctggagct aaccgaggaa
     6601 acttctatgc tgtctcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
     6661 taaaaaagcc gagggatttc ctcgactctt tacatattat ttgttcgtta gttcttaata
     6721 ccagccattg ttaagccaga agtttttagc agcagtccat gaaccgtaac gtcctgcaac
     6781 gtaggcatct gctacacgtt cttggttttc agctgagtag tcaccgttca ggtatgaatc
     6841 tgttaattgg taacgtccga tataacgtcc atttgtagct gtatagctac cacctgattc
     6901 tttttgagcg atccattctt tggcttctgc ttcagatccg cttacagttg aaacaactgt
     6961 ttcacttact actggagttt ctgctactgg agctgaaaca gtttcatctt gagcggctgg
     7021 tgccgcataa gtagctggcg ctggtgttgc aacaggcgct acagggccat cgataaccaa
     7081 ctcttgacca acataaatca aatgaatgtt atcaatgtgg ttgttttctg ccaatttttc
     7141 aactgttgtg ttgtgagttt cagcgatttc tgaaagtgta tcaccttctt taacagtgta
     7201 agttgatgat tcttgagcag atacaaatga tggagcaaat actgcaaaca aggcagctac
     7261 tcctgcaaga gttgctttaa tctttttagt tattgatttc atattcgaaa attctccttc
     7321 tttctatagt tctatcatac cctttaaata ttaccgtttc ttgacacttt tatgtagaaa
     7381 tattacaaaa ttatttttta tttccctaaa taaggtgttt tttgtcataa aagatactat
     7441 ttttatgcta tttgaggtat tagaaaggtt ttcatccaca attaaagcca agcccctcat
     7501 tctttgatat aatagagata agaattttta taaggggaaa ctgatgaaat cacttcgttt
     7561 tcaatctgtc tttgatatca tcggaccagt tatgattggc ccatctagta gccataccgc
     7621 tggtgctgtt cgtattggga agattgtctc ttccattttt gatgatactc cgacagaagt
     7681 tgaattccaa ctttttaact catttgccaa gacctatcgt ggtcacggaa cagacctagc
     7741 ccttgttgca ggtattttag gaatggatac agatgatcct gaaattccaa atagtctgga
     7801 aattgcccac aagcgtggta tcaagattgt ctggaccatt cagaaagaca gcaatgcccc
     7861 tcaccctaac accactaaaa ttactgttaa aaatgcccac aagaccatca gcgtgactgg
     7921 tatttctatc ggtggaggaa atattcaggt aaccgaactc aatggttttg ccgtctctct
     7981 caatatgaat acaccgacta tcatcatcgt tcatcaagat attccaggta tgattgccct
     8041 tgttacagag gcgctttccc gctatggtat caatatcgcc cagatgaatg tcactcgtga
     8101 aaaagctggt gaaaaagcca ttatgattat cgaagttgac agtcgcaact gtgatgaggc
     8161 tatcgaagaa attcgaaaaa tccctcatct ccacaatgtc aatttcttta aataggagga
     8221 agcatgtttt attctatcaa agaattggtc gagcaagcag atctggactt tcaaggaaat
     8281 gtcgcagaac tcatgattac aacagagttt gaattgaccg gtcgcgaacg tgaagaagtc
     8341 ttccttctca tggaacgcaa tctggaagtt atgaaagcct ctgtccaact tggcctcaat
     8401 gaaaataaat ctcgtagtgg cctgacaggt ggagatgctg ccaaattgga ccactacatc
     8461 aaaaacgaaa aaactttatc agattacacg attctctctg ctgcccgaaa tgctatcgca
     8521 gtcaatgaac acaatgctaa aatgggcttg gtctgcgcta ctcctaccgc aggaagtgcc
     8581 ggttgtctcc cttccgttct cactgctgct attgaaaaat tagacctcag ccacgagcaa
     8641 caattggatt tcctctttgc tgctggtgcc tttggactag tcatcgcaaa caatgcctcc
     8701 atctcaggtg ctgagggtgg gtgtcaagct gaagttggtt cagcctctgc tatgagtgct
     8761 gccgccttga ctctggctgc aggtggaaca ccttatcagg ccagtcaagc tattgccttt
     8821 gtcattaaaa atatgctagg cctcatctgt gaccctgttg caggtttggt cgaagttccc
     8881 tgtgtcaaac gtaatgccat gggagctagc tttgctttca tcgcagcaga catggccttg
     8941 gcaggtatcg aatctaaaat ccctgtggat gaagtgatcg atgccatgta ccaagtagga
     9001 gcaagcatgc caactgcctt tcgtgaaaca gctgaaggtg gactcgctac cacccctact
     9061 ggtcgtcgcc tccaaaaaga aattttcgga gaataagctt atcaaatagg agaaaccatg
     9121 acctctatca cagcgatttt tttcgatttg gatggaaccc tcgttgatag ttctatcggg
     9181 attcacaatg cctttaccta tacctttaaa gagctggggg tgcctagccc tgatgctaaa
     9241 actattcgtg gttttatggg accacctctc gaaagtagtt ttgcgacctg cctgtccaaa
     9301 gaccaaattt ctgaagccgt gcagatatat cgttcttact ataaggcaaa aggcatctat
     9361 gaagctcaac tctttcctca gattatagac ttgcttgagg agttatcgag cagttatcca
     9421 ctctacatca ccacgacaaa gaatacatct actgctcaag acatggcaaa aaacttggaa
     9481 atccatcatt tctttgatgg catttatggt tctagccctg aagcacccca taaggcagat
     9541 gtcattcacc aagccttgca gacacatcaa ctagtccctc aacaagccat catcatcgga
     9601 gataccaagt ttgatatgct gggagctcga gaaacaggta ttcagaaatt ggccgtcact
     9661 tggggatttg gagagcaagc agatctacta aactatcaac ctgattatat cgctcacaaa
     9721 cccttagagg ttttggcgta ttttcaatag catagactgg gtaacaattc catttcagaa
     9781 gaaaatgaag taatactcaa tgaaaatcaa agagcaaact aggaaactag ctgcgggctg
     9841 ctctaaacac tgttttaagg ttgtagatgg aactgacgaa gtcagctcaa aacactgttt
     9901 tgaggttgtg gatagaactg acgaagtcag taaccatacc tacggcaagg cgacgttgac
     9961 gtggtttgaa gagattttcg aagagtataa gtctctacat aataaaacgc atattaccaa
    10021 ggttgtgtaa cttgatacta tgcgtttttc ttttttattc aatgtgggtt gtttgattag
    10081 caaaggcgat aatagcttgc ttcaactcat ctccactgag agtgcggaac tctccaatct
    10141 tttgattgat ggattctaaa ggcatgacat taaccttacc aacgaaaatc ttatccataa
    10201 cttgattatc aacgagttcg gttgatacca agagttcttc gtagagtttt tcacctgggc
    10261 ggattccaac ttcaacgatt ggaatttcac tttcagtgtg gccacttaga agcaccatct
    10321 tcttggccaa gtcataaatc ttgactggtt tgcccatatc aaggataaag acttccccat
    10381 ctttggcata agcaccagca tggataacca gacgactagc ttctggaatg gtcataaagt
    10441 aacgggtcat gcggaagtct gtcaccgtta caggcccacc ttcagcaatc tgacgttcaa
    10501 agactggaat gacactacca cggctaccaa gaacattccc aaaacgaact gcacagtagg
    10561 ttgattggct acgttggtta aagccagtga caatcaactc cgccacgcgc ttggttgctc
    10621 ccataacatt tggtggattg actgccttat ctgtcgaaat cataaccatc ttagacactt
    10681 tagcttcatc aacagcctta gcaacattgt aagttccacg gatattgttt ttgaaggctt
    10741 cttttggatt gcgctccatc ataggaacat gcttgtgggc agccgcatga taaacaatag
    10801 caggtttgta ctgctcaaag acttgcaaca aacgatcata gtcttgaatg tccgcaatca
    10861 caggtacata atcaatccct tggaacttac gaatcaattc atgataaaca aggtagattg
    10921 agttttcccc atgaccgagc aagacaatgc gttcaggatt gaagcgacta acttgacgac
    10981 agatttcaga accgattgaa cctccagctc ctgtgactaa gatggtctta cctgtcagtt
    11041 ctgcacccag acgcgattcg tcaagacgga tttcctgacg acccaaaagg tccgtaatat
    11101 caattttttg gaagccagta cctgcttggt gaaggccctg aacaacagtt tcaaccttag
    11161 gcatcttgta acatttgaca cccagcttat tacacatctg caagatacgc tcatattctg
    11221 acggatccag cgacggaatc gcaacgatga cacgctcgat ttgatggcgt ttggctaatt
    11281 caggcagatt gtcataagag cccaaaacag gaataccacc aagtttttga ccctttttct
    11341 tagaatcctt atccaaaata ccgaccagtt ctaattcact ggttggatgt tggtaactat
    11401 ccataaagag agccccacca tcaccggcac caatcaagaa ggtccgacgg tgttctccat
    11461 caccactacc ttttttgcgt ctggagtaga ttaactgcca agtaatccgt ggcaataaaa
    11521 tcaagaaggt actcaacaag ataaagagaa tgatgaaacg gatggagaag agtggcaaga
    11581 aggcataaca gatactatat gacaagacac tgctagcagt cacaccaaaa aagattttca
    11641 tgaaatccgt aatcttgctg taacgactaa tgctcgcgtt caacccccaa aaaccaatca
    11701 tcaattgata gaacaagaag gccaaactcg tatagataat gtagtcaaca ggtgctggat
    11761 taatcagccc ataaaataaa atataagata caatgatgga aaccaccata ctgaaaatat
    11821 caaatattcc ccaaaaaacc tgcttttgtt gtttatttaa aatttccacc agatcaatca
    11881 cataatctgt tagtttttta ttcatagaaa tctactcctc cttaaaagag ttttactata
    11941 ttgttattgt agcatatttt gatttatttg gcttatttta tccaaataaa ttattgttct
    12001 cttgtactcc ttcttccatt taaatcctct aattaaacct acaatcgtcc caaggccata
    12061 agcaaagtga atggaaaata aaagaaaggg catcacaatt agaaatccat ttttatgttt
    12121 taataaagtc agcaaagtga gtaatgacaa aagtagaaaa taggcaccta atagtaaagt
    12181 tatgaatacg aatgtgatcg gtaacaatgc tagactaaac acaagactca aaacaaataa
    12241 acaaggaaca tagtgaaata atgataaaca cttaaactga acatgacttg tcaagccaat
    12301 ccacaaacca tttgaatact tttgatgcag cattttcttg aatgttggtc gaatatactg
    12361 ataagataga atacttgggc tatagcggat tttataacca tattctcgaa ttctataatg
    12421 aatatcatta tcttcagttc ggccaagttg ctcatttact aaaccaacct tctggaaaac
    12481 ctctcgttta tacattccat gaaaaataga agaaacatat ctatcctcag aactatttcg
    12541 ataattggca atgctactgc caaacatatt ttcctcaaca agatgcaagg tctctgccca
    12601 ttttcctttt ccttcgacaa tcgtcggtct aggcccccca cagacaaatt caccttgttg
    12661 aataatagcc acattgttca ttacaaaagt ctcagtaact tttgaatgag catcaatttt
    12721 taaaataagg tcccctacag aatgtttaac tcccaggtta aaaccactag cttgattttt
    12781 cttaggattg ttatacaatc taattgagtt aaactctgta tcttccttta taaattgctg
    12841 aatgatagct gtggtcccat ctgtggacat agcatttata aatagaattt caatattctc
    12901 tttaggatag gtttgatttt ttaagtcttc aattagacca ggcagatatt tttcttcatt
    12961 gtatgcactg attacaatgg atacgagaag actttcaaca ttttgagtca ctactactct
    13021 cctgaatttt tccttccacc attctatcat aattttcaag actttcccat ttttatcttg
    13081 aaagccagaa accttacttg acattatagt gaaaaagcct taaaataagc tgttattaaa
    13141 atcagctaga agaggtatta tatgaaaaag caatcactct tttttgttcc aggtattatc
    13201 ctgattggtg tttccttgcg aactcctttt actgttttac ccattatttt gggaaatatt
    13261 tcgcaaggtc tggaggtaga agttagttcg cttggtgtct tgaccagcct gcctctcctt
    13321 atgtttaccc tcttttcacc attttctacc caactggctc agaaaatcgg cttggagcat
    13381 ctcttcacct acagcctctt cttcttgacc atcggctcac ttattcgact aatcaatctg
    13441 cccctgctct atctaggaac cttgatgatt ggggcaagtg tcgcagtcat caatgtcctg
    13501 cttcctagtc ttatccaagc caatcaacca aagaaaattg gttttctgac caccttatat
    13561 gtaacgtcta tggggattgc aacggctctg gcttcctatc tagctgtgcc cattacacaa
    13621 gccagttctt ggaaaggact tatcctcctc ctcacgttac tctgtctagc aacttttttg
    13681 gtctggctcc caaatcaccg ctataatcat agactagctc cacaaaccaa acaaaaaagt
    13741 caaataaagg tcatgcgtaa taaacaggtt tgggcaatta ttatcttttc aggttttcaa
    13801 tccttgatct tttacaccgc catgacctgg ttacctacca tgtctatcca tgcaggtcta
    13861 tccagtcacg aagctggctt gctgacttct atcttatctc tgattagcat tcctttttca
    13921 atgaccatcc caagcctgac aaccagttta tctactcgca accgtcagct catgctcact
    13981 ctggtttcac tagctggtgt ggtcggcatt tccatgctct ttttcccaat caataatttc
    14041 atttactggc ttgccatcca tctcctcatc ggaaccgcaa ccagcgccct cttcccttat
    14101 ctcatggtca acttttcact caagacaagc gcccctgaaa agacagccca attgtccggt
    14161 ctatctcaaa caggaggcta tatcctagca gcctttgggc caaccctctt tggttacagt
    14221 tttgacctgt tccactcttg ggtaccagct gtagctgccc tcttgctcat cgatatcctg
    14281 atgactgtgg ccctctttac agtggacaga gcggataaga tcctttaaac ttctagtttt
    14341 agctagaagt ttttttatat ataaaaattt tacacatttc tcttgacagg gctttctttt
    14401 agatgtacaa tgtatgtgta gaaaaattat atataaaaat cttacacatt agaaaaggag
    14461 gtttcccatg tactttccaa catcctctgc cttgattgaa tttctcatct tggccgtact
    14521 ggagcagggt gattcttatg gttatgagat tagccaaacc attaagctga tcgctaatat
    14581 caaagaatcc acactctatc ccattctcaa aaaattggaa ggcaatagct ttctgacaac
    14641 ctattctaga gagttccaag gtcgcatgcg caaatactac tccttgacaa acggtggtat
    14701 agagcagctc ttgaccctaa aagatgaatg ggcactctat acagacacca tcaatggcat
    14761 catagaaggg agtatccgcc atgacaagaa ctgaatacct gactcagcta gaactctatc
    14821 tcaagaaact acctgaagct gaccgtatcg aagccatgga ctatttcaga gagctctttg
    14881 acgatgctgg aatcgaagga gaagaagaac tcatcgctag tttgggaact cccaaagaag
    14941 cggcccacga agttctatcc aatcttctcg ataaaaaaat caatgaagca cccgctcaaa
    15001 aaaataaccg acaaatttta catatcgcct tgttagccct ccttgcagca cctatcggca
    15061 ttcctctggg aatcgccatc ctcgtgaccc tgttcgcaat ccttgtagcc gctttgactg
    15121 tcattctggc tttctttgca gtttccatac tgggtatcat cggcggattc ctatttttag
    15181 ttgaaagttt cactgtcctc gcccaagcca aatcagcctt tatcttgatt tttggttctg
    15241 gtttactggc tatcggtgct tcttcgctag ttttacttgg catttcctat gtaactcgct
    15301 tcttcggtct actcattgtt cgtctggtac aatttgttct taaaaaagga aagagaggta
    15361 atcagcatgc gtaaatggac aaaaggattt ctcatctttg gtgtggtgac taccgttatc
    15421 ggctttatcc tgctttttgt aggtatccaa tatgacggga ttaagagcct actttccatg
    15481 tccaaagaac ctgtctatga tagccgtacg gaaaagctaa cctttggcaa ggaagtcgaa
    15541 aacctagaaa ttactctcca ccaacacacg ctgaccatca cagactcttt cgatgatcaa
    15601 atccacattt cttaccatcc atctctttct gctcaccatg atcttatcac caatcagaac
    15661 gatagaactc tgagtctcac tgataagaaa ctgtctgaaa ctccgtttct ctcttctgga
    15721 attggtggga ttcttcatat cgcaagtagc tactctagtc gttttgaaga agttattctc
    15781 cgactaccaa aagggagaac tctaaaaggg atcaacatct cagccaatcg cggacaaacc
    15841 accatcataa atgctagcct tgaaaatgcg accctcaata caaacagcta tatcctccga
    15901 attgaaggaa gtcgtatcaa aaacagtaaa ctcacaacgc ccaatatcgt taatatcttt
    15961 gatacagttc ttacagatag tcagctagag tcaacagaga atcacttcca cgctgaaaat
    16021 atccaagtcc atggcaaggt tgaactgact gccaaagatt atctcagaat catcctagac
    16081 cagaaagaaa gccaacgaat taactgggac atctcaagca actatggttc tatcttccaa
    16141 ttcacaagag aaaagcctga atcaagaggt acggaattaa gcaaccctta caaaactgaa
    16201 aaaaccgatg tcaaggatca actcattgcg agatctgatg ataatattga tctaatatcc
    16261 acaccaagca gacgttgaca aaaacgctta catctgctac tatggaagca tatttatcta
    16321 accaaaagga ggttctacca tgaaacaaga atggtttgaa agtaatgatt ttgtaaaaac
    16381 aacaagcaag aacaagcctg aagagcaagc tcaagaggtt gcagacaagg ctgaagaaac
    16441 gatagccgat ctcgatacac caattgaaaa aaatactcag ttagaggagg aagtctctca
    16501 agctgaagtc gaattggaaa gccagcaaga agagaaaatt gaagctcctg aagacagtga
    16561 agcgagaaca gaaatagaag aaaagaaggc atctaattct actgaagaag agccagacct
    16621 ttctaaagaa acagaaaaag tcactatagc tgaagagagc caagaagctc ttcctcagca
    16681 aaaagcaact acgaaagagc cacttcttat cagtaaatct ttagaaagtc cttatatccc
    16741 ctaccaagct ccaaaatcta gggataaatg gaaagagcaa gtgcttgatt tttggtcttg
    16801 gctagtggaa gcgatcaaat ctcctacaag taagtttgaa acaagtatca cacacagtta
    16861 cacagccttt ctcttgctca ttctgttttc tgcatcttcc tttttcttta gtatctatca
    16921 catcaaacat gcttactatg gacatatagc aagcattaac agtcgcttcc ctgagcagct
    16981 agctccttta actctttttt ctatcatctc tatcctagta gcgacaacac tcttcttctt
    17041 ttcattcctc ttgggtagtt tcgttgtgag acgatttatc caccaggaaa aggactggac
    17101 gctagacaag gttctccaac aatatagtca actcttggca attccaatct tcctcactgc
    17161 tattgctagt ttctttgctt tctttgatag cctacgattt acagctctct tgtgtgtgat
    17221 tagcattgga atcattctgc ttgccagtct ccatatcatt acaagaccaa gtcaagcaag
    17281 tgaaaccgac tccttctatc aattattctt gtctgtcctt gtgaacggag ttattatcct
    17341 cctcttcttt gtagctgaag tggcactgat tggagattat cttcgtatct tggcctttct
    17401 ttaaaattca atcctgtcat ccttagcagg attttttcta tgtcaaaaaa gcaagtcgat
    17461 tgacctgctt ctgctttact tttcttgtgc taatgtttta aaatcttgtc ctaggatggg
    17521 ttgtatttct atttgattgg cgtctagttg gtggtaaaaa gataggggta atacctctaa
    17581 gaattttgca tagtccaagc gggcaatggc ttcatagtct tctggtttag agccatctcc
    17641 tgtgatttga accaagtcaa tctcccactg gacttcctta tccaccaatt gctcaatata
    17701 ggctgcagga acaaacggtt ctctcggtaa aactgtcttg actccttgag ctagatggta
    17761 aacgccatgc acttttcctt ctccatcctg atagaaggaa actctcgcaa agtaggcatc
    17821 tgtctcttga accgcacgca cacgcgcttc aaactgagcc aagccatctg cctctaaaaa
    17881 gcttttcaag ttctcacgac taaagaaaat aggattaaaa attccttggc aaatcgtaaa
    17941 acgagctaca gggtctgcta gataggcttg aatacttgct tggaaataag cttcaaaatc
    18001 aaaaccatct agcccttcaa tatcagtccc tgtataagca agcaaagcat ctaaaaatga
    18061 cttgataatc tgccagtctg tctttgttag taggtcagga agatcgacac ggtaagcctt
    18121 ttgaccatca gcataactga ccttaaagag aaattgtgat tgccccacta tcgcacactc
    18181 gatatattcg agacgattaa gaggctgacg gagatagact acatcatagc tatgtgactc
    18241 caaaccgtct agcaaggcca agatcgactt ggcagtcaaa atctcttgtt ctcctaaaat
    18301 gctctgttta tttggaataa aaaatgtttt cgccataact ggactccttt gaaatcgttt
    18361 acatacagta taccttattt ttctgaaaga tacaaaaaca aactttagat ttttgagtac
    18421 aaagcataga aaaacagccc ctgaggactg tttgatctta tacagtagct gcttgatcca
    18481 agctttcacc gatagcggct aggcgctcga tcacttcagc ttgtgtcaat tcattttttg
    18541 aaacatagcg gttacgtggg tgaacacggc actcgtgtga gcatccacga aggtacttgt
    18601 cttcattttc ttctgatgtc aagatacgac ggttacagaa gggatttcca cagttgacat
    18661 aacgttcaca tggtgttcca tcaaaccagt ctttccctac gatagttggg ttgacatggt
    18721 tgacatcaac ggcaatacgc tcgtcaaaga cgtacatttt cccatcccaa agctcacctt
    18781 gaacttctgg gtctttaccg taagttgcga ttcctccgtg caattggccg acatctttgt
    18841 aaccttcacg aaccatccag cctgagaatt tctcacagcg aacgccacct gtacagtaaa
    18901 ccacgacacg cttgtccatg aatttttcct tgttatcacg gacccattgt ggtaactcac
    18961 ggaagttgcg aatatctggg cgaatagctc cacggaaatg tcctaggtcg tactcataat
    19021 cgttacgtgt gtcaaggaca acggtatctt tatcaagaag cgcttctttg aactcttttg
    19081 gagacaagta agcacctgtt gtttcaagtg ggttgatgtc attgtcaaag tcgttgtctt
    19141 ccaaaccaag gtggacaatt tctttcttgt agcgaacaaa catcttcttg aaggcttgtt
    19201 cattttcttc gtcaatcttg aaccagagtt cttccattcc tggaaggctg tgaacgtagt
    19261 ccatgtattt ttgagttgtt tcatagtcac ctgaaactgt tccgttaatt ccctcgtcag
    19321 cgactaggat acggccttta aggccgattg atttacagaa agccaagtgg tctgcagcaa
    19381 attgctctgc attttcaatt ggagtataaa ggtagtaaag taagacacga atatcttttg
    19441 ccataagatt tgttctcttt tctattctta aattttctaa attttttatt tatctacact
    19501 agtatacctg cttgagaaaa cgaatgcaat ttatttgact ggaaattgta gagggttctc
    19561 gaaatttcct gaatggttaa aataaggaca agagaaaaca tggatatcta tatccttgtg
    19621 ccaaaaaaac cactgccctc cccagaccaa cctgaggaaa gcagtgattc ttattttagg
    19681 agttaggaat gaatacacga aatcaattta gctgattatt ttttgttttt caagaattca
    19741 tcgtattgtt tttgcatttc gttcaatact ttttcgtagg caccttcaga tttcaatttt
    19801 tccatcaatt ctggaatcgc tttatctggg tctacagtac cagtgttgat agctgtatca
    19861 aattgttgca ttgtgttagc aatagctgag atttcagatt tcacattgtc agtattgaag
    19921 ataaatccaa gcgctggaga ttctttagct tctgccaatt ctttcttaga attttcgatt
    19981 tgttggtctg taacgttttc gttgatgtaa aggatccagt tgttaccagt gttccatcca
    20041 cccatgtgag tgtttccttt gtagccatca agaacgcgaa cacggttttc tttaccttca
    20101 attttttccc agttcttgcc ttctggaccg taaacaagac cgttcaagag ttctggattc
    20161 gtattcaaga ggttcaagat ttccattgat ttttctttgt tcttagagtt gtttgagatg
    20221 acaaagttag caacttgtgt tgtttggttt ttcttgatga agttagtaat tggtttgatt
    20281 tggatatctt tgttggcaac acgtgaaagc aagctgttac cgtagtcaac tggtcctact
    20341 gtttcttcac gaacgaacca agtatcttgt tgaaggtcaa aggaagtatc gcttgttgcg
    20401 acgtcttttg gaatgtagcc agcttcatag aatttgtgaa gagtcttcaa gtgttctttg
    20461 aaacgaggca cttcgtaacg gtttacaact ttagtagtat cgccttcaag gtcgataacg
    20521 aatggaagac cgtttgctac tgggtagtca aagttatcag atgggatgaa aactttacca
    20581 atagcaaatg gtactacgtc tggagctttt tctttgattt gtttcaagac tggctcaaga
    20641 gtttcgtaag aagtaacacc tgaaatatcg ataccatatt tagcaaggag agttccgttg
    20701 aaggcaaagt tttgagatga tgcaacgttg gctgcaactg gaacagcgta aatcttacca
    20761 tttacagtat tacccttgat gtaagctggg tcaagtgctt tgtaaaggtc tttaccttct
    20821 tttttgtaca attctgtcaa gtcagcgtaa gcaccttttt gagcatttac aatatagtta
    20881 tctgcaaagg caatatcata gttttcacca gatgatgtga taactgacat tttcttacca
    20941 tagtcacccc agccaaggta ttggatatcc aatttggcac caactttttc ttcgatgatt
    21001 ttgttggcat ttgctaacaa ttcatccaag ttatctggtt tgtcaccgat ttggtacatt
    21061 tttataacag gtttgtcacc tgaatcagca gcttttttgc tgttacctgt caaatttcca
    21121 caagcagcaa gacctgcagc caaagcgact acactagcag atgcaaaagc atattttttc
    21181 cagtttttca tgataaaaac tccttttttt atttttaaac ttataaacaa tgtaatgatc
    21241 ttatactcaa tgaaaatcaa agagcaaact agaaaactag ccgcaggttg ctcaaaacac
    21301 tgttttgagg ttgtggataa gactgacgaa gtcagttaca tatatctacg gtaaggcgaa
    21361 gctaacgcgg tttgaatttg attttcgaag agtattaact tcacacaagg gaagttggga
    21421 actgagaaat gttatttctc aataagcact attctttcac accaccgata gtcaaacctt
    21481 ttacaaagta gcgttggaag aatggataca aaatcgcgat tggaagggtt gcaaccacaa
    21541 ccatggccat acgacctgtt tctttcggta gagcaactcc cagttgacca gtcaagccga
    21601 ccgctttggc aatgtagtcc atattttgtt ggatttgcat gagcaaatat tgcaatggat
    21661 acaagttgtc actcttgatg taaagaaggg cgttgaacca gtcattccag aaaccaagag
    21721 ctgtcaaaag cgtgatggtt gcgatacctg gtagtgacaa tggcaaacag atttggaaga
    21781 aaatccgggc ctcactggca ccatcgatac gagccgattc gagaatggct tctggaatgg
    21841 tcttcttgaa gaaggaacgc atcaagatga tattgaatgg tgagagaagc attggaacaa
    21901 tcaaggccca aacagtgtca ccaagctgaa gtacacgggt caccatgata taacctggta
    21961 ccaaaccagc gttgaacaac atactgagaa ggacgaagat ggtaaaaaat ctgcgatact
    22021 taaaggttgt ccgtgaaata gcgtaggcat aggttgttgt gataaagaca tttgtcaatg
    22081 tcccaactac ggttacaaag acagagatga agagggcttg taggatttta tccttaaact
    22141 gtgccaaaaa ctcaaaaccg tctaagccaa attgggatgg gaagaagcta tagccgtatt
    22201 ggaggaggct tttctcgtct gtcactgaaa taatgataac gaatacaaaa ggtaggatac
    22261 aagagagggc aatcaaaccc gaaatgatac tgaagaagat atctgctttc ttactgaagg
    22321 agtgaatgcc gacattatca attttttctt ttttaatttt cttttttgcc atattctcct
    22381 cctttctaga acaaagctga gtttggatcg actcgtcttg caagcaagtt tgataggata
    22441 accagaatca aaccaacaac ggattggtaa agaccggctg ctgcagccat accgatatct
    22501 gctgtctgag tcaaaccatt aaaaacatat acgtccaaaa cgttggttac attgtaaagc
    22561 tgaccagcat tgtgtgggat ttgatagaag agaccgaagt ctgcgcggaa gatatttccg
    22621 actgcaagga tggtcaatac agttacaagc ggagtcaact gaggaatggt tacgttgcga
    22681 atacgttgcc acttgctagc tccgtccact gtcgctgctt cgtagtaggt tggatcaatt
    22741 cccatgatcg tcgcatagta catgacactg ctatatccaa aacctttcca aatacctagg
    22801 aaaagtagga gatagggcca gatgcccagg tcagcgtaga aattgacttc tttgagacca
    22861 agactttcca atagatgatt gaacacccct ttatcaatat ttaggaaggc atctgtaaag
    22921 aaactgatga taacccaaga caagaagtaa gggaacaaca tagaagtttg gaaaatcttc
    22981 accattctct tagaacggag ctcgctgagg ataatggcaa tccctacaga tacaactaaa
    23041 cctagaaaga taaagccaag attgtagagg acagtatttc gtgtgataat aaaggcgtct
    23101 cttgaactaa ataagaatct gaaattatcg agtccgaccc atttactatt tatgatacta
    23161 tctatgaaac cattactggt catgtggtag tctttgaagg caaccacgtt cccaaatact
    23221 ggaatgtaaa agaatagaat caaccagagt gcccctggca aaaccatcaa gagaaagatc
    23281 cagttgtctc tcaatgtttt tgaaaacttt ttcataattt cctccctttt tattttgata
    23341 tccatctaaa aattcttttt tagacttttg ataacgatta cattattagt atactcctat
    23401 ttgcaggtta ggttaaactc ctaattatag aaaaaactcc acaaattatg tagcagattt
    23461 aaaactttat caccactatc aaacaaatgt cctaaatcaa ttgtttattt tatctctatt
    23521 agcccagtga tggcgtcact ctgttataag catccaacaa cggggtatac tgaaaaatct
    23581 ccagactagg gaactcagcg atagttccta atctggagat ttttaatatg ttattaggcg
    23641 tttgctttca acttagcaat aacctcttta agattatcaa tcaactctgc ttcagtatgc
    23701 tcagagcctt tttcatctgc caagaacaaa actgcttttt gaagttcttc ttgagagttt
    23761 tcaaggacat ccttatctgc tgtttctttg cccgctgttt gtcctccatc cttagttgct
    23821 gactggcttt ccttaatgga ctctagggaa gcaatggcat ctttgactgt ttgcaagata
    23881 tcacgtaaac cttgctctgt caaactatca tctgtaagag ctttcttagc ctctgccaaa
    23941 accagacgtg ctgaatctgt ggtaggattc gatacacctg tcaatgatct caaaagattt
    24001 tctaaggttt gagtctgctt actaatacta gactaaaatc aaaaagcatt acataacagt
    24061 gatatgaaat caactaaaga agaaatccaa accatcaaaa cacttttaaa agactctcgt
    24121 acagctaaat atcataaacg ccttcaaatc gttctatagt aaaatgaaac aagaacagga
    24181 caaatagatc aggacagtca aatcgatttc taacaatgtt ttagaagtag atgtgtactg
    24241 ttctagtttc aatccattat atttcgtctg atgggcaaat cttataaaga gattatagag
    24301 cttttatagt gatttgaaat aagatgtgaa caactctatc aggaaagtca aattaattta
    24361 tagaaatatt ttaacagcca aggtgtactg ttataaattc aatacactat acttggtggt
    24421 ttagctctcc tgttttctct tttagcttta accagccata aatggtatta cgtgagattt
    24481 gaaaaacgtg tgatgcttct gttatactac ctgttcgctc acaataagag agaacttttt
    24541 tacgaaaatc tattgaatat gccataaaag attataccac attgtgtact atttttggtt
    24601 cattttacta tatcactttg gactatatcg gtctagttat gtctaaacga ttatagctgg
    24661 atactaagag aaatcaaaaa agcactaagg gagaacgtcc caaagtgctt aatatcaagg
    24721 cctcaaagcc tatcttattt aataaaatat tacaacattt tgttgtagaa ttcaacgaca
    24781 agtgcttcgt tgatttctgg gttgatttcg tcgcgttctg gcaagcgagt caatgaacct
    24841 tccaactttt cagcgtcgaa tgatacgaat gctggacgtc caagagtagc ttctactgct
    24901 tcaaggattg ctggaacttt caatgatttt tcacgaactg agatcacttg acctggagtt
    24961 acgcggtatg atgggatatc aacgcgtttc ccgtcaacaa ggatgtgacc gtggtttacg
    25021 aattgacgag cttgacgacg agtagtcgcg agaccaagac ggtaaacaac gttatccaaa
    25081 cgacgttcca aaagaagcat aaagttgaaa cctaggattc cgcctttgat ttttgtagct
    25141 tgtacgaaca agttacggaa ttgtttttca cctacaccgt aagtgaaacg aagtttttgt
    25201 ttttcagcca attgcaaacc gtattctgac aatttagaac ggttgtttgg tccgtgttgt
    25261 cctggtacgt agttacgacg tgccaattct ttacctgtac ctgtaagtga aaggccaagg
    25321 cgacgagctt gtttccaaga tggtcctgta taacgtgaca tatgaatgtc ctcctgatat
    25381 aaataatatt tcggtggaaa tagtcactta gaaagccctg attcgtgcag atgcccttcg
    25441 cctaaacagc caaggttact tgtcataaga cacctgttga cgagcttcat gctttcctgc
    25501 tgatatttca cacaaaatct attctaccat gaatagctgg atttgtaaag gggttttagg
    25561 ctttattttc actaccagag aggttgagaa cgagggtaaa ggtacttcct agaccgtact
    25621 ggctgctgac tgtgatttcc ccacccaatt gatgggccaa ttcacgcgca atcgcaagtc
    25681 ctaatccatg accacctgtc ttcatgttac gcgaagtttc gacacgataa agacgtttga
    25741 aaatattttc caaatcctct ggggcaatac cctgcccttc atcggtcaca ctgattgaaa
    25801 gctggtcctt ctccagctta gccaccactt ccagcttggt tcctggagca gaatatttaa
    25861 aagcgttatc gaccagattc accaagatac gagaaagctt agcataatct ccctcaatcc
    25921 gggcagactc tgggattacc tgcaagtgga catctcttct ctcctgctca atcaaaaact
    25981 gaaattcact catgcactca attaagagct tgtccagaaa aatactgtct ttactggtag
    26041 tttccacctg atttctagct gtgtttaggg tcaaaaaatt caactcctca accagtttat
    26101 tgagcctctc cgtctggcgt ccaatggttg ctagataatg agcttgctcc gactccttga
    26161 taatcccatc caaaatccct tctaccgtcg cttgaatcga agtgataggg gtcttaatat
    26221 catgcgacaa ctgggcaatc atcaagccct tttctcgttc gctttcttcc aaggaatcaa
    26281 agcttacctg caaatcatgg gacatctcat taaaagtttg ccctaattgc tgaaattcta
    26341 caggaccttg aacctccaaa tttgaaggaa aatccttggc cgctacccgc ttggcatgct
    26401 ccttgagttt gcccaacgac gtaaagactg gcaataggag aaagagacta atcccagcac
    26461 cgacaaggct ggcaacgatg gtcatcccaa gcaaaaagta aatctcgcct ttcgcaatca
    26521 gcattttttg aacagcccaa aaaacaacca aaatggttaa gagggttgaa ataatatatc
    26581 caaccaaaat ataacttttt agtttcatgt ttgtcctctc ggtttctcta tcttatatcc
    26641 caacccccaa actgtcttaa tagtgggcgt ttggtcacta ctatattttg ccagctcctg
    26701 tcgaagagca tggatatgca cattcaaggt attggtgtca tccacgtagt cttctttcca
    26761 gatcttttca tagaggtctg tcttggagaa aactcgctct ggattgctag ctaaaatcca
    26821 cagcaattca aatgatttaa cagttaaatc cagcatttct tctcctattt gaacttcatg
    26881 actactatga ttcattttta gattgccaag ggaaatcagc tctgtttcgc ccccacgatg
    26941 aaggcggcgc aaaatattgt ggacacgcaa aactagctca cgtgggctaa aaggcttagc
    27001 aataaaatca tctgctccca agctcaggcc gtaaatcttg tcctgttcac tggtcttagc
    27061 agtaataaat aggaaaggct gctctggtga taagtattga acctcactga ttaaatcata
    27121 accatccatc cgaggcatca tgacatctgt gataatcaaa tcaatcggtt ttttcttgaa
    27181 cagctctagc gcttccagtc catcatgggc taccaagacc tgataacctg cctgaattaa
    27241 gtatctctga tgaatatctg tgatttctac ctcgtcgtca acgagtaaaa ttgtctttcc
    27301 catctgtctc tcctttgata aaaacagtgc tatactgctt taagtataac actattttta
    27361 ttgttttacg atgattttaa tctgctattg aaagaaagtc ctgattgctg attgagttgt
    27421 taaactaatc ttagtcagcc cactatccat catttatttc cttagctgat tagttttctt
    27481 cttttttgtt tttcaaacct agaccaccga gtaaacctgc aagcgcaagc ccaaggaaac
    27541 caatacttgc cattgatgtt tgagtctcac cagtatttgg tagcatagct ttatcctctg
    27601 acatcatcgt atcagacatc ttgttagcag aagcagccat gttttcacct gccatcgtgt
    27661 tggtagaact tgtcatggtg tcagcaggca tgctatctgt agtacctgta gcatgattgt
    27721 gattcatcgg agtcacgcca gaaccagagt tagaaggtga taatgaacca tttgctgtgt
    27781 ctgatgtttc tttaacattt atcttaatag tgactttttt agttgctacg atgttgtcca
    27841 agtctggttt accgtctttg ttaccataga cattgactgt agcgctgtaa gtttgagtac
    27901 cgtttgctcg gaactggtca atgagcgctt gtttttcttt gccagctaca tttccgtcca
    27961 aggctacttg atagaagtat tgacctttgg tcttcacgtt ttcgcctagt ggagataggg
    28021 ctgggttttt agcctcaccg ttatctgacc atggtgcctt gtcagatgcc ttgagcaaga
    28081 gacgagtcaa cat
//
LOCUS       DAVMBH010000025        26442 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVMBH010000025 DAVMBH010000000
VERSION     DAVMBH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.025"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(98..2356)
                     /locus_tag="VYP30_001222"
     CDS             complement(98..2356)
                     /locus_tag="VYP30_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1808219.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDTKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VYP30_001223"
     CDS             complement(2585..2815)
                     /locus_tag="VYP30_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1808220.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VYP30_001224"
     CDS             3005..3688
                     /locus_tag="VYP30_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808221.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VYP30_001225"
     CDS             3688..4422
                     /locus_tag="VYP30_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808222.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VYP30_001226"
     CDS             4576..5433
                     /locus_tag="VYP30_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1808223.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAVGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLTIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VYP30_001227"
     CDS             5575..6447
                     /locus_tag="VYP30_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1808224.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP30_001228"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP30_001228"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1808225.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VYP30_001229"
     CDS             7426..8637
                     /locus_tag="VYP30_001229"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1808226.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VYP30_001230"
     CDS             8639..9181
                     /locus_tag="VYP30_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1808227.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKFESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VYP30_001231"
     CDS             9197..10006
                     /locus_tag="VYP30_001231"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1808228.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10503..11525
                     /locus_tag="VYP30_001232"
     CDS             10503..11525
                     /locus_tag="VYP30_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1808229.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDDQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILYHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVYMLAIRGTRVNDAKDLSADLVLLGGNKPAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     DAKNGF"
     gene            11535..12110
                     /locus_tag="VYP30_001233"
     CDS             11535..12110
                     /locus_tag="VYP30_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1808230.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSFSQPSAEPME
                     NIALGKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12135..12647
                     /locus_tag="VYP30_001234"
     CDS             12135..12647
                     /locus_tag="VYP30_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1808231.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13301..14011
                     /gene="deoD"
                     /locus_tag="VYP30_001235"
     CDS             13301..14011
                     /gene="deoD"
                     /locus_tag="VYP30_001235"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1808232.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14034..14558)
                     /locus_tag="VYP30_001236"
     CDS             complement(14034..14558)
                     /locus_tag="VYP30_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1808233.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14611..14847)
                     /locus_tag="VYP30_001237"
     CDS             complement(14611..14847)
                     /locus_tag="VYP30_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1808234.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14915..15835)
                     /locus_tag="VYP30_001238"
     CDS             complement(14915..15835)
                     /locus_tag="VYP30_001238"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1808235.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16033..16437
                     /locus_tag="VYP30_001239"
     CDS             16033..16437
                     /locus_tag="VYP30_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808236.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16653..17234
                     /locus_tag="VYP30_001240"
     CDS             16653..17234
                     /locus_tag="VYP30_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1808237.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            17231..18508
                     /locus_tag="VYP30_001241"
     CDS             17231..18508
                     /locus_tag="VYP30_001241"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1808238.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18526..19188
                     /gene="deoC"
                     /locus_tag="VYP30_001242"
     CDS             18526..19188
                     /gene="deoC"
                     /locus_tag="VYP30_001242"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1808239.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASADKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            19175..19564
                     /locus_tag="VYP30_001243"
     CDS             19175..19564
                     /locus_tag="VYP30_001243"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1808240.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19655..20707
                     /locus_tag="VYP30_001244"
     CDS             19655..20707
                     /locus_tag="VYP30_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1808241.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20851..22386
                     /locus_tag="VYP30_001245"
     CDS             20851..22386
                     /locus_tag="VYP30_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808242.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISESIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22379..23437
                     /locus_tag="VYP30_001246"
     CDS             22379..23437
                     /locus_tag="VYP30_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808243.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23440..24396
                     /locus_tag="VYP30_001247"
     CDS             23440..24396
                     /locus_tag="VYP30_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808244.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSVVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            24481..25829
                     /locus_tag="VYP30_001248"
                     /pseudo
     CDS             24481..25829
                     /locus_tag="VYP30_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            25958..26442
                     /locus_tag="VYP30_001249"
                     /pseudo
     CDS             25958..26442
                     /locus_tag="VYP30_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7854 a         4746 c         5927 g         7915 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctcattttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgt atcataacct aggtcaacca
      301 acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag attgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaggaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggttggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattaac cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttgaccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa tcgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaagc attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 ggagacaatg cttttggaga agatttagtt aaacaggtct ttgctggctt aaaacagaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattacaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatt aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtcat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcggata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aagtttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aaggggaagt gcctctgttt tttcaggatt gactgcctat ccggattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagctttcta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatttgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag actcacctat tcttgctcct gtagaagaaa
    10681 ctaaagaaga agctgtgaca gaaaaaccaa caaatactcg ttctctaact gcagaagatt
    10741 tggtgaagat ttccaaaggg gaattgcatt tagaaaatga tttgattgat gaatctttct
    10801 atggtgaaaa agctcttgat ttggaagggg atgatgacca ggatggcatc aaaaacaaag
    10861 atggtaagga ttatctagga tataacagtc atcccttgct agcagacagt gatggggatg
    10921 gtttggcaga tggggaagat gataataaga aagaatggta tgtcacagac cgtgattctc
    10981 ttctctttat ggagttagct tatcgagacg atgattatat tgagaaaatt ttatatcata
    11041 agaatctttt ccctagtctc tatcttgacc gtcaagaaca caaactcatg cacaatgaat
    11101 tggctccttt ctggaagatg aaaaaagcct actatacaga tagtggcttg gatgctttct
    11161 tatttgagac caagagcgac cttccttatc tcaaagatgg aacggtgtac atgttggcta
    11221 ttcgtggaac gcgagttaat gacgccaagg acttgagtgc agatttggtt ttattaggtg
    11281 gaaataaacc agctcaagcg gatgatatcc gcaaggttgt tggggaatta gccaaggata
    11341 taagtattac taagttgtat atgacaggtc attctcttgg aggctaccta gctcagattg
    11401 cagcggttga agattaccaa aaatatcctg atttttataa ccatgtattg aggaaagtga
    11461 caactttcag tgctcctaaa gtcattactt ccagaactgt ttgggatgct aagaatggtt
    11521 tctgagatgt tggtttggaa agtcgtaaat tagctgttag tggaaaaatt aagcattatg
    11581 tggttgataa tgacaatgtt gtgactccct tgattcataa taatcgtgat attgttacat
    11641 ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta ttttgaaagt ccaatgaatg
    11701 atattcctaa ctttaatatt ggtaaacaag ctaccttgga taaacatggt tatcgtgatc
    11761 cgaaattgga taaagtgcga ttctttaaga aacaggctct gcctcgatct tttagtcaac
    11821 caagcgctga accaatggaa aatattgcct taggaaaaca ggttactcaa agttcgacag
    11881 ttttcggagg agatgctaga agagctgtgg atggcaaagt cgatggtaac tatggtcaca
    11941 attctgtcac tcatacaaac ttccaatcta agccttggtg gcaagtagat ttggctaaag
    12001 aagaaaccat tcgccaaatc aatatttaca accgaacaga cactgcccag gatagattgg
    12061 caaactttga tgtcattctt ttagacagtt ctggtaaaga aattgagtga aaacgtataa
    12121 catctcctaa agatgtgtca gcacaaatta cgattaacca taaaaaagtg cgctatgttc
    12181 ggattgagct agaaggctat aatgccctca gtcttgcaga agttgaagtt ttccgcttta
    12241 tagctacgaa tgctgaaacg gcgacacaag tttctaagcc agttcaacca atcagtcaga
    12301 ctcctgtgaa agataaaaca ttgacaattc aacacagtgg agcttacatt gcccgctact
    12361 ccataacttg ggaagaagtt ccagtagata aagatggaaa ccaagttgtt cgtagtcatt
    12421 cttgggaagg aaacggttgc aaccagactg caggttttgt cctcaacctc ccaatcaaag
    12481 aaaatatgag aaatctgcga gttaagattg agaaaaagac gggcctacta tggaatagat
    12541 ggcaaacaat ctatgaaaac agaccaattt tagctcaacc ccaccgtaaa attacccatt
    12601 ggggtacgac attgaattcc aaggtgagtg acgatgatgt cttgtaatct gatggtacaa
    12661 tgacagttag tttgtctagt ttataagaaa gtactacctg agcttgaata gaactcaggt
    12721 agctctctgt gaaagaacaa aattaatact caatgaaaat caaagagcaa actaagaaac
    12781 tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtc
    12841 acatatataa tccaaggcga cgttgacgtg gtttgaagag attttcgaag agtataaaca
    12901 gaaaggtaga gcgcgtgttc taatttgaac acgagtagaa aacttttcta aaaacaaaaa
    12961 cgaaaggatg ggtaaactgt attcgctgaa ctgaatacgg gcgactctcc tctaaatcaa
    13021 aattaagaaa ggaattgacc ccaccctaaa agtagtggga aaaagatagt tgatctagcg
    13081 agcatcgctc actgcgccca actcctattt tcccttcgct ttttgatggg tttggtatct
    13141 ttctcaatat aaaatataaa ataaagaaag gtagagcgtg tgttttgatt tgaacacgag
    13201 cggaaaactc ggaaaataga taatctgact gaaaaatcag gatttctcgt caggttccta
    13261 attttcagtc gttttcttct cgctctttgt atcataaatt atgtctatcc atattgctgc
    13321 tcagcagggt gaaattgctg ataaaattct tcttcctggg gatcctcttc gtgctaagtt
    13381 tattgcggag aatttccttg atgatgctgt ttgttttaac gaagtgcgta acatgtttgg
    13441 ttacactggt acttacaagg gtcactgtgt atctgtcatg ggaactggga tgggaatgcc
    13501 atctatttcg atttatgcgc gtgagttaat cgtagactac ggtgtgaaga aattgattcg
    13561 tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt cgtgaattag ttttggcgca
    13621 ggcggctgca accaactcaa acatcgttcg taatgactgg ccacagtacg attttccaca
    13681 aattgctagc tttgatttgc ttgataaagc ctaccatatc gccaaagaac ttggtatgac
    13741 tactcacgtt gggaacgttt tgtcatctga tgtcttttac tcaaattact ttgaaaagaa
    13801 tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg gaagcagcag ctctttacta
    13861 tcttgctgcc caataccatg ttgatgcgct agctatcatg accatctctg atagcttggt
    13921 caatccagac gaagacacaa ctgcagaaga acgtcaaaat accttcactg atatgatgaa
    13981 ggttggtttg gaaaccttga ttgcagaata attatagcca aaaaggaagc cctttatgaa
    14041 ttgtaggact tccttttctt atccagaaat tgatctagct ctctctgatt tcgaagaata
    14101 gtgactttat gtgaatattc ttggcaaagt ttttggtaat tttctttttg agttttgcta
    14161 cgcccatccc aaagaatcca tctgataaac tcccactcaa agcgttcagg gcaatctgcc
    14221 gccatacttt ctctgacttt tccacggtat ttaagataac gcttaaaggc tctaaagaga
    14281 caggtcaatg gcgaaaaatt gagaaagatg atttggtcag cttcttgcat tcgttcttgg
    14341 tagtagcacc aagaataatt accatcgatg acccaagctt tatgcttggt gagaaagttt
    14401 tttatctcgg ttaacatcca ttcgtggtca ctgtcttgcc aaccaggttg aaattggagt
    14461 gtgtccatgt gcagttttgg aatggagtag tagttagata acttttctgc tagagttgac
    14521 ttaccagaac cagaatatcc gataattgcg attttcattt tctacctttt cctatttgga
    14581 gacaaaaaaa cagcctctat ggactgtttc ttatttagca agtttagctg aaagacgagc
    14641 tttatcgcgg cttgctttgt ttttgtgaat caaaccttta gtttctgctt tatcgatagc
    14701 tgagctagca gcacggaaaa gttcttcaga tgggtttgct tcgaaagctt ttatagcagt
    14761 acgcatagct gatttttgag ctgagttctt ttcgttttgt ttaacgttca attcagcgcg
    14821 tttgatagct gatttaatgt ttgccaatgt tcttacctcc atatttacta actataccat
    14881 tatatatgaa aacttacgtt ttgacaaggg aaaattactt ttttaagtaa atttcatcga
    14941 tttcatggtt cttgctttta tgaagaatca cttctgcacg atttctggtt ggttcaatat
    15001 aattttgcag atttgtgaga ttgatactga tccagacctg atgggcaaag gcttccactt
    15061 ccccaatcgg catctgagta aaacgataat agtagctatc agggtcgttt tgggctagac
    15121 tcagcatttt caagaaacgg tccagatacc aactttcaat atcatccact ccagcatcta
    15181 catagatgga aaagtcaaag aagtcagtga tatagagacg atcgttttgt ggattttgaa
    15241 agacattgat tccctcaaca attacaaaat cagcagcttt gacactttgt ttctcttcgg
    15301 gtacgatgtc gtaaacttca tgagaataga caggaatatc tacatcttgt ccatttttga
    15361 tgcggtccaa gaagttgaga agagcttcca tatcatagct ttcaggaaat cctttacgat
    15421 ttaaaatccc ctgctcaatc aaggtttgat tgggatagag aaaaccatca gttgtaacca
    15481 actcaaccgt agcatctgta aacgtacggg acagtaggat ttgaagtagg cgactggttg
    15541 tggattttcc aacggcaaca ctcccagaaa ccccaataat aaaaggttga gatttacttt
    15601 cacgttggag gaaaattcct tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct
    15661 gaatcagatg agctaagggg agatagatat ctgtaacgtc ttggagactg atttggtcat
    15721 taaaactctt gatagattcc aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta
    15781 aagattgcca agtctggcgg ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt
    15841 ttcccctaga tattttgtct atcataccat aaaaatctaa aaaaataaag cggtttcttg
    15901 aatgtggtaa gtcaatggta tatagtataa gtgatcaatt tattgatgaa ataggagata
    15961 gattctactg atttataagt ttataagctt ataaaggggg ctttttagtt cacaacttat
    16021 aggaggtgta ctatgaaaat cttaaaacgt tacatattgg aactctgttt tattttaagt
    16081 tttgctttac cttttataaa aggagccaat gcagataatg gtatatgctt tgtggaaacc
    16141 tattacggtt ttactttttt gatggaacat gctattgtaa cagctgtctt tatctattcg
    16201 tttttaattg ctttcttact aaaaaaacga tgggcgaaat ggattgctgc tggtagttat
    16261 tgctttttag tcctatggat tgcgacagag ggttatttct tccgcatgtc actagaagat
    16321 ttgatacgac tttggacaag tttggaaatc ctgacacaaa cgtatcagtt gggcttttat
    16381 ctaaacattt tgttaggaat tttgttgata ataaagtatt ttaaggttaa gcaatagaaa
    16441 taataatctg cctgattata gatgataaac tttttgtttt tatctggact gtgatattta
    16501 tagttctaaa tggtttatta tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg
    16561 acttgctttc ttcggtcttt ttcgttttat tatcaatttg taaacgattt acaatttgag
    16621 tcaaattatg gtaaaatagt gtcatgagta aaatgtatta tgcagaaaat cctgacgctg
    16681 ctcacgacat tcatgagttg agagtagagt tgttgggaca aaaaatgacc tttttaacgg
    16741 atgcgggtgt ttttagcaag aaaatagttg actttggaag tcaactattg ctcaagtgtc
    16801 ttgaggtcaa ccaaggagaa actgtccttg atgtaggctg tggttacgga cctttgggtt
    16861 tgtccttagc taaggcttat ggagttcagg ctactatggt tgatatcaac actcgtgcct
    16921 tggatttagc tcggagaaat gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca
    16981 acatctatga acaagttgaa ggacattttg atcatgtcat ttccaatcct cctatccgtg
    17041 cgggcaagca agtcgttcat gaaatcattg agaaaagtaa agatttcttg gaaactggtg
    17101 gggatttgac aatcgtcatc cagaaaaaac aaggggctcc aagtgctaag tccaagatgg
    17161 aggatgtgtt tggtaattgt gaaatcctta aaaaagacaa gggatactat atccttagaa
    17221 gtgtgaaaga atgagagcag ttgatttaat acaaaaaaaa cgagacggtc aagaactgac
    17281 ttcaagtgaa attgaatggc tggtagaagg ctatgtgtca ggaactgttc ctgattatca
    17341 gatgtctgcc tttgctatgg ctgtttattt taaaggaatg acgactcgtg aaatttctga
    17401 tttaacgatg aatatggtta agactgggca agagtttgac ctgtcagcca ttgatggtgt
    17461 gaaagttgac aagcattcta ctggtggtgt cggcgataag gtaaccttga ttctagctcc
    17521 tcttgttgct agcttcggtg tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac
    17581 aggcggaaca attgataaat tggagtccat taagggctat caagtagaac gtagtcaaga
    17641 ggattttatt cgtcaggttc aggatattgg agtatctgtc attgggcaat cagaccagct
    17701 ggtcaaagca gataagcttc tctatgccct tcgtgatgtg accgcaactg tcgacacgat
    17761 tcctttgatt gcgagttcgg tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt
    17821 gctagacgtg actgtcggtg agggtgcctt catgaagacg gttgatgagg cgcgtgagtt
    17881 ggctcaaact atggtagatc ttggtaaggt tgttggacgg aagacagtag cagtgattac
    17941 ggatatgagc cagcctttgg gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt
    18001 ggagattttg caaggtcaag gacgtcagga tattacccac tttatttgtg aattggctca
    18061 aattatgctt ggtttggcaa atgttaacaa gactgttgaa gaagttcgcc aacatcttga
    18121 gaatggtcaa gcactggcta agtttgagga aatggtgcaa gcccaaggtg gagacttgga
    18181 agacctctat cgtcctgtaa atgtagctca tgtggtggaa atccctgctc aggaaacggg
    18241 tgtcatttca gctcttccag ctatggactt tggtctttat gccatgaggc tgggtgctgg
    18301 tcgtgcagtt aagtctgatg ccttggacta tgaaacagga attgtttttg aaaagaagat
    18361 tggagactcc gttcaaaagg gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc
    18421 acctcaacta gttacagatt tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat
    18481 ccgtgaaatt gtagaaatca tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa
    18541 tatatagatc atacgctttt aaaacaagat gcaaagaaaa aacaaattga tagtttgttg
    18601 tctgaggcta gagagtatga ctttgccagt gtttgcgtta atccgacctg ggttgaacat
    18661 gctaaaaaag gacttgaagg cacagatgtt aaggtttgca cagtagtagg tttccctttg
    18721 ggagcaacaa cttcagccgt gaaagcattt gagacaaaag aagctatcca aaatggtgca
    18781 gatgagattg atatggtgat caatgttgga gctctcaaat caggtaattt agccttggtt
    18841 gagtcagata ttcgcgcagt agtggaagca agtgctgata agttagtgaa agtcattatt
    18901 gaagcttgcc ttctgacaga ccaagaaaaa attgttgttt gccaattggc ccaaaaagct
    18961 ggggctgact ttgttaaaac atctactggt ttttcaactg gtggtgctac gatagcagat
    19021 gttacattaa tgcgtgaaac agttggatct gatatgggag tcaaggctgc tggtggagct
    19081 cgttcttatg cagatgctct tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca
    19141 gctggggtag ctattttaaa aggagaattg gcagatggcg actactgagt tgattgaact
    19201 ggcaattgaa accagcaaac atgcctatgt cccctattct cactttccta tcggagcagt
    19261 tttagtagcc aaagacggaa atgtttacac gggagtgaat atcgaaaatg ctagctatcc
    19321 tttgaccaat tgcggtgaga gaacagctat ttttaaggct atatctgaag gccaaagaga
    19381 attttcagaa ttgattgtct atggtcaaac tgaaaaaccg atttcaccat gtggtgcttg
    19441 tcgccaagta atggtcgaat tttttgaaca agatttaaaa gtgaccttag tcgcaaaaga
    19501 taaatcgacg gtcgagatga cggtcgggga gttacttcca tattctttta cagacttaaa
    19561 ttagtctgag tcgctctttg agtggcaagg gtctttgtga ccaatcaatc catacttgca
    19621 acatcgttgc acatcttatt taggaggttc agtaatgaac aagaaacaat ggctaggtct
    19681 tggcctagtt gcagtggcag cagttggact tgctgcatgt ggtaaccgct cttctcgtaa
    19741 cgcagcttca tcttctgatg tgaagacaaa agcagcaatc gtcactgata ctggtggtgt
    19801 tgatgacaaa tcattcaacc aatcagcttg ggaaggtttg caggcttggg gtaaagaaca
    19861 caatctttca aaagataacg gtttcactta cttccaatca acaagtgaag ctgactacgc
    19921 taacaacttg caacaagcgg ctggaagtta caacctaatc tttggtgttg gttttgccct
    19981 tcacaatgca gttgaagaag cagctaaaga acacactgac ttgaactatg tcttgattga
    20041 tgatgtgatt aaagaccaaa agaatgttgc gagtgtaact ttcgctgata atgagtcagg
    20101 ttaccttgca ggtgtggctg cagcaaaaac aactaagaca aaacaagttg gttttgtagg
    20161 tggtatcgaa tctgaagtta tctctcgttt tgaagcagga ttcaaggctg gtgttgcgtc
    20221 agtagaccca tctatcaaag tccaagttga ctacgctggt tcatttggtg atgcggctaa
    20281 aggtaaaaca attgcagccg cacaatacgc agccggtgca gatattgttt accaagtagc
    20341 tggtggtaca ggtgcaggtg tctttgcaga ggcaaaatct ctcaacgaaa gccgtcctga
    20401 aaatgaaaaa gtttgggtta tcggtgttga ccgtgaccaa gaagcagaag gtaaatacac
    20461 ttctaaagat ggcaaagaat caaactttgt tcttgtatct actttgaaac aagttggtac
    20521 aactgtaaaa gatatttcta acaaggcaga aaaaggagaa ttccctggcg gtcaagtgat
    20581 cgtttactca ttgaaggata aaggggttga cttggcagta acaaaccttt cagaagaagg
    20641 taaaaaagct gtcgaagatg caaaagctaa aatccttgat ggaagcgtaa aagttcctga
    20701 aaaataatgg atggaagtca tttcttagga agcggccaag ggccgctttt ttaagagttg
    20761 agacaaagtc attttgtctc agtaaagctt gctactagac aaactagcaa gttttattga
    20821 aataaaataa gactctgaaa ggaagagcac atggcacacg aaaatgtcat tgagatgcgt
    20881 gatattacca aggtgtttgg tggatttgtt gctaacgaca aaatcaactt gcacctacga
    20941 aaaggtgaaa ttcatgcact tttaggagaa aatggggctg gtaagtccac gctaatgaac
    21001 atgttagcag ggcttcttga accaactagt ggtgaaatcg cggtcaacgg tcaagttgtc
    21061 aatctcgact ccccatctaa agcagctagc ttgggaatcg ggatggttca ccagcacttt
    21121 atgttggttg aagccttcac agtggctgaa aacatcattt taggtagtga attgactaaa
    21181 aatggtgtgc tagatatcgc tggagctagc aaagaaatca aggctctttc tgaacgttat
    21241 ggcttagctg ttgacccttc tgccaaggta gcagatatct cagttggagc ccaacaacgt
    21301 gtagaaattt taaaaacact ttatcggggg gctgatatcc ttatctttga cgaaccaacg
    21361 gctgttttga ctccatcaga aattgatgag ttgatggcta ttatgaaaaa tcttgtcaaa
    21421 gaaggaaaat caattatctt gattacccac aaattggatg aaattcgagc agtttctgac
    21481 cgtgttacag ttatccgtcg tgggaaatca attgaaaccg ttgaaattgc aggggctacc
    21541 aatgctgatt tggcggaaat gatggtagga cgttctgttt cctttaaaac agagaagcaa
    21601 gcctctaaac caaaagaagt ggttttgtct atcaaagatt tggtggtcaa tgaaaaccgt
    21661 ggtgttccag ctgttaaaaa tctgtccttg gatgttcgtg ctggagagat tgttggtatt
    21721 gcggggattg atggaaatgg tcagtctgaa ctgattcaag ccattacagg tcttcgtaag
    21781 gttgaatctg gtagcattga gctaaaagga gattcaattg taggcttgca cccacgtcag
    21841 attacagaac taagtgttgg gcacgttcca gaagaccgtc accgtgatgg cttgattttg
    21901 gaaatgatga tatctgaaag tattgccctt caaacctact ataaagaacc acatagtaaa
    21961 aatggaattt tgaattattc aaatattact tcttatgcta aaaagctgat ggaagagttt
    22021 gatgttcgcg ctgccagtga attagttcct gcagctgcac tctcaggagg aaatcaacaa
    22081 aaagcaatta ttgctcgtga aattgatcga gatcctgatc tccttatcgt tagccagcca
    22141 actcgtgggt tggatgtcgg tgccattgag tatatccaca aacgcttgat tgaagagcgt
    22201 gataatggca aggctgtcct tgttgtcagc tttgaattgg atgagatttt aaacgtctca
    22261 gaccgtattg ccgttatcca cgatggtaag attcaaggta ttgtatcacc agaaacaacc
    22321 aataaacaag aacttggtgt cttgatggct ggtggaaact tgggaaagga gaagagtgat
    22381 gtctaaaaaa ttacaacaaa tttcggttcc cttgatttct gtatttctag gaattttact
    22441 cggagccatt gtcatgtgga tcttcggtta tgatgctatt tggggctacg aagaattgtt
    22501 ctatacagcc tttggcagtc tgcgtgggat tggagaaatc ttccgtgcta tgggtcctct
    22561 ggtcttgatt ggtcttggtt ttgcggttgc cagtcgagct ggtttcttta acgtcggact
    22621 tcctggtcag gctttggcag gttggattct cagtggttgg tttgcgctgt cgcatccaga
    22681 tatgccccgt cccttgatga ttctagcaac catcgtgatt gccttgattg ctggtgggat
    22741 tgtcggagcg attccaggta ttcttagggc ctatctaggg acgtcagagg ttattgtaac
    22801 catcatgatg aactacattg tcttgtatgt agggaatgcc tttatccatg ctttccctaa
    22861 agacttcatg caaagtacag attcgaccat tcgtgttggg gctaatgcaa cctatcagac
    22921 accttggttg gctgagttga ctggtaactc acggatgaat attggtattt tctttgccat
    22981 cattgccgtt gcagttattt ggttcatgct caagaaaaca actcttggtt ttgaaatccg
    23041 tgcagttggt cttaatccac atgcttcaga atatgctggt atttctgcca agcggactat
    23101 tatcctatct atgattattt caggtgcctt ggcaggtctt ggtggagctg ttgaaggttt
    23161 gggaaccttc cagaacgtct atgttcaagg ttcgtcatta gctatcggat ttaacggaat
    23221 ggcggttagt ttgcttgcgg ccaactcacc aattggtata ctctttgcag ccttcctatt
    23281 tggcgttctc caagttgggg ctcctggtat gaatgcggcg caggtaccat ctgagcttgt
    23341 cagcattgta acagcgtcta ttatcttctt tgtcagtgtt cattacctta tcgaacgctt
    23401 tgtcaaaccg aaaaaacaag ttaaaggagg taagtaaaga tgtctattat aaccttgctc
    23461 cccctcttgg tgtcttctat gctgatttac tcagcacctc tcatctttac aagtatcggt
    23521 ggtgttttct ctgaacgtgg tggtgtggta aacgttggcc ttgaaggaat tatggttatg
    23581 ggtgcctttt ctgtagttgt ctttaacctt gaatttgcag aacaatttgg agcagcaact
    23641 ccatggctat ccttgcttgt agcaggattg gttggtagtg ttttctctat catccacgca
    23701 gcagcgacgg ttcatttccg tgcagaccat gttgtcagcg gtacggtatt gaacttgatg
    23761 gcgcctgcct tggctgtttt cttagttaaa gttctttata acaaaggaca aaccgacaac
    23821 ctaagtcaaa cttttggacg ctttgatttc ccagtcttgg caaatatccc agtgattggt
    23881 gatatcttct tcaagtcaac tagtctactt ggttatctgg cgattgcctt ctcattcctt
    23941 gcttggttta ttctctttaa gactcaattt ggtcttcgtc tccgctctgt cggtgaacat
    24001 cctcaagcag cggatacctt gggaatcaac gtctacaaga tgagatattt aggggttatt
    24061 atttcaggtt ttctaggtgg aattggcgga gcgatttatg cgcaatcaat ctcagttaac
    24121 ttctcagtga caactattgt tggacctgga tttatcgccc ttgctgcgat gatctttggg
    24181 aaatggaatc caatcggtgc tatgctttct agtctcttct ttggactttc acaaagtttg
    24241 gctgttatcg gttctcaatt gccgttccta caaggagtgc cagcggttta tcttcaaatt
    24301 gcaccttatg ttttgacaat tcttgtctta gcagccttct ttggaaaagc agtcgcccca
    24361 aaagcagatg gtatcaacta catcaaatca aaataagcat acaaaaaaac gtcagtccaa
    24421 tgactgaact accccccaaa agttagacag aaaaaatcta acttttgggg tgtttttatt
    24481 atgaaactaa cttatgatga taaagctcag atctatgaac ttagaaaaca aggatatagc
    24541 ttagagaagc tttcaaataa atttgggata aacaattcta atattaggta catgattaaa
    24601 ttgattgatc gttacggaat agagttcgtc aaaaaaggaa aaaatcgtta ctattttcct
    24661 gatttaaaac aagaaatgat taataaagtc ttacatgaag gctgaactaa agatagagtt
    24721 tctcttgaat acggcctccc aagtcgtacg atacttctta attggctagc acaatacaag
    24781 aaaaacgggt atactattgt tgagaaaaca agagggagag tacctaaaat gggacgtaag
    24841 ccacaaaaga gacctgaaga gaggacagaa ttagaacgtc ttcaatcaga aaatgagtac
    24901 ctgagagcgg agaatgccat cctaaaaaag ttaagagaac tccgattgaa ggaggaaaaa
    24961 gagaaagaag aaagacagaa attgttcaag aattaatgac tgagttttcg ttagttcttc
    25021 ttctaaaatc cattaaacta gctcgttgga cctactacta tcacttgaaa cagctagaca
    25081 aaacagataa ggaccaagag cttaaagctg aaattcaatc catttttatc gaacacaaag
    25141 gaaattatgc ttatcgccgg gttcatttag aactaagaaa tcgtgcttat ctggtaaatc
    25201 ataaaagagt tcaaggcttg ataaaagtac tcaatttaca agctaaaatg cgacagaaac
    25261 gaaaatattc ttctcataaa ggagacgttg gcaagaaggc agagaatctc attcaaggtc
    25321 aatttgaagg ctctaaaaca atggaaaagt gctacacaga tgtgactgaa tttgccattc
    25381 cagcaagtac tcaaaagctt tacttatcac cagttttaga tggctttaac agcgaaatta
    25441 ttgcttttaa tctttcaact tcgcccaact tagaacaagt gaagagtatg ttagaacagg
    25501 cctttacaga gaaatactat gagaatacga ttctccatag tgaccaaggc tggcaatacc
    25561 gacacgattc ttatcatcgg ttcctagaga gtaagggagt tcaagcatcc atgtcacgta
    25621 agggtaacag cccagacaat ggtatgatgg agtccttctt tgggattctg aaatcggaaa
    25681 tgttttatgg ctatgagaaa acatttaaat cacttaatca attggaacaa gctattgtag
    25741 actatattga ttactacaac aataaacgaa ttaaggtaaa actaaaagga cttagccttg
    25801 tgcaatacag aactaaatcc ttcggataaa ttaggctcta taatatttgt agtgggtaaa
    25861 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atgacctata
    25921 atgaaaagcg acaaaacaac tcattagaaa gattcatatg gaacaattac attttatcac
    25981 aaaattacta gacattaaag acccaaacat caagattcta gatatcatca ataaggatac
    26041 acacaaagaa atcatcgcca aactggacta cgacgcccca tcttgccctg agtgcggaag
    26101 tcaaatgaag aaatatgact ttcaaaaacc gtctaagatt ccttatcttg aaacgactgg
    26161 tatgcctact agaattctcc ttagaaagcg ttgattcaag tgctatcact gttcaaaaat
    26221 gatggtcgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca
    26281 aaaaattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
    26341 cacctcaact tcaactgtta ttcgtaagct caatgatttt cactttaaac atgatttttc
    26401 ttgtcttcct gagattatgt cttgggatga gtatgctttt ac
//
LOCUS       DAVMBH010000026        26064 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVMBH010000026 DAVMBH010000000
VERSION     DAVMBH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.026"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(527..1321)
                     /locus_tag="VYP30_001250"
     CDS             complement(527..1321)
                     /locus_tag="VYP30_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808245.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(1321..2328)
                     /locus_tag="VYP30_001251"
     CDS             complement(1321..2328)
                     /locus_tag="VYP30_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1808246.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(2328..3335)
                     /locus_tag="VYP30_001252"
     CDS             complement(2328..3335)
                     /locus_tag="VYP30_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1808247.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(3325..4350)
                     /locus_tag="VYP30_001253"
     CDS             complement(3325..4350)
                     /locus_tag="VYP30_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1808248.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(4743..4961)
                     /locus_tag="VYP30_001254"
     CDS             complement(4743..4961)
                     /locus_tag="VYP30_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808249.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(5207..5485)
                     /locus_tag="VYP30_001255"
     CDS             complement(5207..5485)
                     /locus_tag="VYP30_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808250.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(5699..7330)
                     /gene="rlmD"
                     /locus_tag="VYP30_001256"
     CDS             complement(5699..7330)
                     /gene="rlmD"
                     /locus_tag="VYP30_001256"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1808251.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGLAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(7404..8378)
                     /locus_tag="VYP30_001257"
     CDS             complement(7404..8378)
                     /locus_tag="VYP30_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1808252.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDSDKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(8452..9066)
                     /gene="pmp23"
                     /locus_tag="VYP30_001258"
     CDS             complement(8452..9066)
                     /gene="pmp23"
                     /locus_tag="VYP30_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1808253.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(9066..10040)
                     /locus_tag="VYP30_001259"
     CDS             complement(9066..10040)
                     /locus_tag="VYP30_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1808254.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(10048..11304)
                     /locus_tag="VYP30_001260"
     CDS             complement(10048..11304)
                     /locus_tag="VYP30_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1808255.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPKTELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(11365..11796)
                     /locus_tag="VYP30_001261"
     CDS             complement(11365..11796)
                     /locus_tag="VYP30_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808256.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKVQKRFIRIF"
     gene            complement(11798..12400)
                     /locus_tag="VYP30_001262"
     CDS             complement(11798..12400)
                     /locus_tag="VYP30_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1808257.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFSKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(12384..13223)
                     /gene="prmC"
                     /locus_tag="VYP30_001263"
     CDS             complement(12384..13223)
                     /gene="prmC"
                     /locus_tag="VYP30_001263"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1808258.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(13223..14302)
                     /gene="prfA"
                     /locus_tag="VYP30_001264"
     CDS             complement(13223..14302)
                     /gene="prfA"
                     /locus_tag="VYP30_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1808259.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(14312..14791)
                     /locus_tag="VYP30_001265"
     CDS             complement(14312..14791)
                     /locus_tag="VYP30_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808260.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(14781..15380)
                     /locus_tag="VYP30_001266"
     CDS             complement(14781..15380)
                     /locus_tag="VYP30_001266"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1808261.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            15503..15685
                     /locus_tag="VYP30_001267"
     CDS             15503..15685
                     /locus_tag="VYP30_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1808262.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            15822..17195
                     /gene="mnmE"
                     /locus_tag="VYP30_001268"
     CDS             15822..17195
                     /gene="mnmE"
                     /locus_tag="VYP30_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1808263.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(17242..18177)
                     /gene="dapA"
                     /locus_tag="VYP30_001269"
     CDS             complement(17242..18177)
                     /gene="dapA"
                     /locus_tag="VYP30_001269"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1808264.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(18233..19309)
                     /locus_tag="VYP30_001270"
     CDS             complement(18233..19309)
                     /locus_tag="VYP30_001270"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1808265.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(19651..19723)
                     /locus_tag="VYP30_001271"
     tRNA            complement(19651..19723)
                     /locus_tag="VYP30_001271"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19688..19690),aa:Thr,seq:ggt)
     gene            complement(19823..20332)
                     /locus_tag="VYP30_001272"
     CDS             complement(19823..20332)
                     /locus_tag="VYP30_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1808266.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(20330..20426)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            20455..20886
                     /locus_tag="VYP30_001273"
     CDS             20455..20886
                     /locus_tag="VYP30_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1808267.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            20968..21345
                     /gene="mscL"
                     /locus_tag="VYP30_001274"
     CDS             20968..21345
                     /gene="mscL"
                     /locus_tag="VYP30_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1808268.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(21387..22481)
                     /gene="hemH"
                     /locus_tag="VYP30_001275"
     CDS             complement(21387..22481)
                     /gene="hemH"
                     /locus_tag="VYP30_001275"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1808269.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            22635..23855
                     /gene="pepT"
                     /locus_tag="VYP30_001276"
     CDS             22635..23855
                     /gene="pepT"
                     /locus_tag="VYP30_001276"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1808270.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVRSL"
     gene            complement(23898..24527)
                     /locus_tag="VYP30_001277"
     CDS             complement(23898..24527)
                     /locus_tag="VYP30_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808271.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            24492..24713
                     /locus_tag="VYP30_001278"
     CDS             24492..24713
                     /locus_tag="VYP30_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808272.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(24822..25067)
                     /locus_tag="VYP30_001279"
     CDS             complement(24822..25067)
                     /locus_tag="VYP30_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1808273.1"
                     /translation="MVMVFDANRIISEDSEGFVIPHGDHNHYIKVQTKGYEAALKNKI
                     PSLQSNYQPGTFDEKAVLAKVDQLLADSRSIYKDRLS"
     gene            complement(25174..25269)
                     /locus_tag="VYP30_001280"
                     /pseudo
     CDS             complement(25174..25269)
                     /locus_tag="VYP30_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(25339..25479)
                     /locus_tag="VYP30_001281"
     CDS             complement(25339..25479)
                     /locus_tag="VYP30_001281"
                     /inference="COORDINATES: protein motif:HMM:NF016182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1808274.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAVA
                     KV"
     gene            complement(25523..26064)
                     /locus_tag="VYP30_001282"
                     /pseudo
     CDS             complement(25523..26064)
                     /locus_tag="VYP30_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         7705 a         5231 c         4627 g         8501 t
ORIGIN      
        1 aaaatgaaac agatataaaa ttttcaaaaa ctctataatt tttatcatct atatcttcgt
       61 agtaacctaa gataccattg tcaatatttg tagcactaat tctaggagtt tttccatcga
      121 gtaaatatct ttttggaata gatgagcctg ttggtacttg actcgatttc cccttttttt
      181 cggtaataaa tatttctttt tattttgttg tctgatattt ttcctacctg tcctttgtag
      241 gatgagtatt ttctagattt tcttgaataa ctttttactt gaagttttag cttttgaact
      301 agtcgttgta ctttcttttt gtttattatc agtcctgatc tttttaatat tgctgttatt
      361 ctctatatcc tatttttcat tcatgatatt cttttactaa ttttatctta aattctgtgc
      421 tgtatttgcc attaaaaaac tgacctcctt tagttagttt tttgtcctaa cttttgaggg
      481 tcagttcaaa agttgcgact tttaaatgaa ttccaatatt caattattaa gagttaacat
      541 ggtgcttgcc aataggaatc attagaggcg aattggaaat agggtcacgt ataatttttg
      601 cttcaagatt aaagatatct ttaactagtt tatcatttag tatatcttca ggctttccct
      661 ctgcaacaag tttaccttct ttaattgcaa ataggtaatc agcgtatctt gctgttagat
      721 ttatatcgtg caaaatcatg caaatggttg tcttatattt ttggtttaga tcagtcaaga
      781 ggtctaatag ttctatttga tatgagatat ccaagtaagt agttggctca tctaaaagta
      841 ggatacttgt atcttgggct agggctagag ctatccatac tctttgcctt tgacccccag
      901 aaagttcttc aactaggtta tttgctagat cttcaacatt ggccataacc attgatctgt
      961 ttattatttc aaggtcatct tttccaagac tcttaaaagg ctttctgtag gggaaacgac
     1021 cacggcttac aagatcagct actgttattg attcagggat tattggagat tgaggtaata
     1081 tagctatgtg ttttgctaaa tctttttctt tataagaatt aattgattta ttatcaagca
     1141 atacttctcc ctctaatggc tttataagtc gagacaaggt tttaatgagt gttgatttcc
     1201 cacaaccatt tgacccaata ataactgata ttttttcttc aggtattttt atatttatat
     1261 tttccaagat tattttttca tcataaccgc aggtaagatt atttgaccac agacctttca
     1321 ttatatattc ctcctgttca tttttattag taaatatatt aagtatggtg aacctaacaa
     1381 gccagttaca acacctactg gatatctagc tggtaaaata ttttgagaga atatgtctga
     1441 taacaaaact agtaaaattc caaccaatcc agctaatatt gggcttcttt tcttgccaat
     1501 atttaaggct atgggaccag ctaaaaaaga tatacaagct attggtcctg taattgaagt
     1561 agaaaaagca gttaaagata cagcgcaaaa aattaaaaca agccttgaaa gctcgggatt
     1621 tgcaccaagt ccgattgcta tttcttcacc aagttcaata atttctagtc ttttattaaa
     1681 aaataaaact aatatagtag caataatact tactattaga acaagaggta tgtcatctaa
     1741 ctttgtaaaa gataaagagc cactgagcca tctcataact tcttgtaatt catatcttgc
     1801 tactttcaac aataaaaatg aggtgcctgc tcttgtgaca gcttgaaaac caatacctaa
     1861 tattatcagt cttgctgctg aaaaaccatc ttttttagct agtaaaaata atattaaaga
     1921 tgatgttagt ccacaagtta ttgaaataat tccagtagtt aaactatttg tttttaatac
     1981 caatatgcaa aagaccgctg caatagatga agaacttgtg acaccgatta tatcaggact
     2041 tgcaagagga tttcttaaca tagtttgaaa gataaatcct gccaatccaa aagaccagcc
     2101 agctataatt cctgctaata attttggtaa tctaatttcc ataatcgaaa aactagctcc
     2161 aggaacagtt tcactattta agactttaat caaagttgaa aaagaataac tttcatctcc
     2221 gataagtaaa atgaaaaatg atagactgat tattattaat aaaaatagtg aggagaatag
     2281 tgttattcta ttttttcttt tttgaatacc tataattaaa ttttgcatta gttattaacc
     2341 cctctatttt tcatagttac ataaataagt actggacccc cgattattgc agtaattatc
     2401 cctacttcaa tttcacctgg tttacctaac atacggccga ttatatcaca tataagcaag
     2461 agctctgcac ctataaaaga tgaagaaatg gtcattgtgc gtatatcttt gcttataaat
     2521 aagccacaaa agtgaggaac tataagacct acgaagccaa taggtccacc aattgcagta
     2581 atacttgaac ataaaagcac acttgcaatt attgcaagtg atcttatcct attaacatta
     2641 actccaagac caacagccat ttcatcaccc atagctaaag cgtttaaatc tgatgaaata
     2701 aatatagcta tcaagtgacc taaaattata aaaggtagta gtgtagatat agaagataat
     2761 gtagctgctc caaggctacc tatttgccaa aatctaaatt tgtctaagac gttattattc
     2821 ggtaaaatta aaaaacttac aaaactgctt aaagccatac taacacaagt tcctgataag
     2881 gcaagtttta taggggtaag gcctgctttt ccgcttacag caatcgcgta tacaaaaatt
     2941 gcacttacta agccaccaat gattgcaaaa cttatatggc ttatgcttga tgaaattcct
     3001 aaaaaagaaa gaccaattac tacactaaga cttgctcctg tgtttatacc gagtatacct
     3061 ggatcagcta ttgggtttct agtaactgat tgcatcaata caccgcttat ggcaagacta
     3121 gaacctgcta aaattgcaaa aatagttcta ggtattcttt tatatataat tgatttaata
     3181 aaatcatcat ttgtattacc cattccaaaa gctgctaaaa aatctctgat attaatttct
     3241 tttgttccaa gctttaatga caaaaatatt gtaataagaa gacctaggca gattacaaaa
     3301 attatgccta ggtttatttg ttttttattt cgcatttttg catgcatttc ctaaaagatt
     3361 tagatattct tcaatagtat agtttattga aagtggtgtt ggagtgcatg aggctgctaa
     3421 cggtgtatta tctggaatta cagcaacggc accattttta attgcattta ttttacctaa
     3481 aagaggatct ttttgtaaag cttcaagagt tttatcatca ccataagtta tgattacatc
     3541 agcatcattt atcttatttg cttcttctgc agaaatttcc tttgcaaaac tatcttcact
     3601 ctcaaattct tttaatgatt cagggaaaac tagacctaaa tctgttaaat aatttgctct
     3661 tggatctttg ctagtataaa tccagaattt tgatgtatct gcagcattaa tcatagtaaa
     3721 taatactttt tttcctttga tttttccttt gatttctgga tgtttttcta attctttgga
     3781 tatacgagct tcagtatttt tgattaactc atcaccttct ttttccatac ctaaggcttt
     3841 tgaatcaatt ctaatcatat ctctccataa agtttgccaa ggtttagatt tgtatgctgc
     3901 tacaggagca atttttgata gagtgtcata atcttcttta gttataccag aataacctgc
     3961 taagataaca tctggtttag aatttgatat tgcttcaaag ttaagtccat ccaaatcgtc
     4021 aaataggtta gctttaccat ttagttcttt gattttttct tctgtccatg gtaaaactcc
     4081 tttatcagca cttacaccgt aatttgcttt tgaaagtcca acaggaacta ttcctaaagc
     4141 taatgctaca tcatgatttc cccaagcaat agttgcaact ctttcaggtt ttttatctaa
     4201 tatagtttga ccgaaagcat gatctaaaac tattttatca ggcgcatgct ctttagaagt
     4261 attttcttca tttttaacag aattagaaga acaagcgcta aaaactatac acatagctaa
     4321 aatagctatt agaaaaaatt tgtttttcat aaaaactcct taaacatatt tcaagtctat
     4381 tgtatcgata ataattatca ttgtcaatag atacagttac aaatttaata atataatttt
     4441 ttcaaaaaag gatctagttt ttatttttag ttaaattatg tctatatttt tcattaactc
     4501 atcaataaaa atttgtttgc taatatctct ttcttctgat tttgtttcaa ggattattgc
     4561 tacatcattc atatttttag gtaaatacca accatctggc ttatctgaat atcccttgaa
     4621 gcctaattga ttaaaagtag ttatttgacc agtaccttga ttgatgtttt cttcaacttc
     4681 attaaagcct atacttctct tgcataatcc ctaacttgat cttctgtcct taaagtcatt
     4741 ttctattcct cgtcactaaa attatcttca aaactaataa tatcattagg agtgcaagat
     4801 aaagccttac atattctttc taaattctta aatgtaattg gtttatcctt tcccatttgt
     4861 gccataacat ttgttgtaag tcctgccata gctattacat ctgttttctt tagtcctttt
     4921 tttgctaact gtatccataa tggtttatag ttaagtgcca taatatccct ctttttttct
     4981 tcattaaatt tatttaatta tagcataaat attgatttca ttcaatctta cattgattta
     5041 gtgatttgtt ttagagaatt tgttgtgtta ttccgtcctt attttgccat aaattgtttt
     5101 aagtgggacc tcttatcctt accattttta cctcctaatt ttgagtataa aaaagacgat
     5161 agagttttta atttctatcg tctgagattt acatattaaa ttttcatcac aaaataagac
     5221 tctttaaaga atctttaaat tcattggtat gctgcttaca atatccatta ttaaaatgga
     5281 tattgtaagc agcacaccaa ctatttattt tttgagtttt aaactttggt agaagtcttg
     5341 aactccttat atttacataa ctatttgcct ctataactgt tatgacacga aaccaacaag
     5401 caagttcaag cacctccata tctttattca aatgaggact aagatattca caaactttat
     5461 cataaacctc tttatctttt ttcataaaag gggcatacaa cttagcaaat ttatcctaaa
     5521 attttttgtt gcctttatca atcatttcaa cgctccttta aatataaaaa tgatcctatc
     5581 aatctttata ttgagcctat tttctaattg ataccttgca agaaaggaat aatagctgtt
     5641 cctataccaa gtaggaatgt aataaatgca gaaagtcata tactgtcatt cttttctatt
     5701 aaatcatttt gaagtgtctc aaagcatcca tgatggcttc ttctttttca ggtgtacact
     5761 gtggaataat ttgtttatcc tttttagact tgttgtaatg ttctcgtaat tctattccac
     5821 atttcttttt tatctgtgca atatataatg tcgaaacttt taattcaaat ttattccaaa
     5881 catattcttt gatttgagca tatgttgctt tgctctccgc acttgtcaaa tccatctcat
     5941 ccagctcaat ttcaacactt atgtgcttat cgacatcgag tttggacaaa agtgctaccg
     6001 tctcgacgtg atgcgtttga ggaaatagat ccaccggctg gactttcttc aattcatatc
     6061 ccaactcttg gtatagttta atatcacgcg ccatggttgc gacattgcag gagatatagg
     6121 cgatgcgatc ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc aagcccttgc
     6181 gtggaggatc aaccaagata acggttggtt gaatcccatc tttaagccaa ttcttcatag
     6241 cattttcagc tgtgtcacag acatagtggg cgtttgaaat attgttcagc tgagcatttt
     6301 ttttactatt ctcaaccgct tctggaatca gttcaacacc gtagacttct ttgacatgct
     6361 tggcgactga taaaccaatg gttccaatac cagaataagc atcaataacc acgtcatctt
     6421 tttttaactc tgcaaagtca atggctgttt gatagagttt ctccgccatt tcagtattga
     6481 cttggtaaaa ggctaggcca gcgatttgga agtcatttcc caacatctgg tccgtaatat
     6541 agtcttgacc ataaagagtg cgccactcct taccaaaaat cgcattggta ttctggtcgt
     6601 tgatattttg catgacagac acaatctctg ggaactgctt gataacttgt tcaatcaatt
     6661 ggtcaacacg aaaaactttt ggacgagttg tcaccaaaac gaccatgatt tgtcctgaat
     6721 agtgaccacg acgcaccaca agattccgaa tcaatccaga ctgttccttt tcgtcataag
     6781 gttttaaatc aaaacgacgg agcaggtctc gaagagctac tacgacttgg tcaatgacag
     6841 gatcctggat aaagaaatct tcaaggggca tgaggttgtg cgaattctta cggaaaaatc
     6901 ctgtttccaa gacaccattc actcgacgaa cgggcacctg cgccttattg cgatacttga
     6961 ctggatgttc cataccaagc gtttcagcaa cttctacatc tgcaattcca gcaatcttgt
     7021 agagactgtc cttgacttgc ttggttttaa acttgagctg ttctggataa gaaaggtgtc
     7081 ctaaatccgc gattcctgaa cgcaggtaag ccaaatctag atcttgatta cggtgtggtg
     7141 actggacaag gtatttttca acttttccaa agccaatctt tttattgacc ttgaggacac
     7201 gcatgagaat tttttcactc ggtaaagcat tctctacaaa aaagaccaaa ccatctacct
     7261 tggcaactcc tgccccttca tgggtcaaat caacaatttc aacttctaca atatcatttt
     7321 tctttaacat tcttttctct ttctattggc cgacaaaaaa gacggcaacg ttacggttac
     7381 catccattat accatgaaat ttcttaagaa ccaaaactct tgaagaagtt gacaagggct
     7441 tgccagaggg agcttaagaa gttaccaccg tcctctagcg ccttatccga atcaaagtta
     7501 aggttgatat ttttaaaact gtcgccagct tgtgatacga tgctttgttt aaggtcattt
     7561 aaggttttag tgaaatctgc attgctgagg atatcactct ttgagagatt caaggcaaaa
     7621 ttgatgatga tattgatctg gtttcctgtt atgacctgat caagtttgta attttttaag
     7681 gtatcttcaa caatcttgcg gatatcttct tctgtcagat ttcccttgct ttctttagct
     7741 ttggcgagtc ctgacttgat atcagctagg gcaacgttta atttattagc atcatagcct
     7801 gatttgtcct tgttttcagc attgatatct gacaaagcct ttagctcttc ttgagccaaa
     7861 tctttattgg cttgcggcac cttggctcca ttagcttcta gcgaatagta gatcccagcc
     7921 aaagcactct cacctgtaac tggaatgggt gctgctacag tgattttggc gtgttccaca
     7981 cccaaagtta cggctgcatt tcggtacata tcctgagtta ccttagtgat gttttcaggt
     8041 gtttcaatct tgacctcaag tggcgatttg tcacctagct tttgaatctt ggctgatgaa
     8101 tacaactgta agctagagtc attggccaca ttcatgattt tagaataaac atcaggtgtc
     8161 atggtcttga gttctttggt atctgttgag gcattgtagc ccagtttttt aagagtttga
     8221 tttttttggt cttcagatag ggaagaacct aggacatatt caggttggac ataggtttca
     8281 tcgataactt tttgaacatc tgttgctgca tggacgctat tcatagctgt tactgcccac
     8341 aagatcgcag cgctagtcag aaagagtttc tttctcatag ggaatttcct cctttacttc
     8401 tttagagtaa tatatctatc ttaaagaaaa cttataataa aaacacctgg tctagccaga
     8461 tgttgaaaag agagtgaaac atttgatgat gtaaaggtta agtcgtacct gtctagaata
     8521 ataatagttt cctccattta catagagttc agcaccgtga aaaatggaaa tggggtgaat
     8581 ataactataa gtctttccag tcctattacc aagcaagggg gcaacagtct cacgagagta
     8641 ctgtttggct agagccaagg tattttcctt gccattttgg gcgataaaat cgatataggc
     8701 aggtccaaaa ttataggctt gaacagctgt ccagatatct acacccttct tctgcgccag
     8761 atagagattg cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat tatcattgat
     8821 ggtgttggtg gaaccacttg cagactcact agactgcata acatcgcctt cttttccttt
     8881 tgtttcagta taaatcatag caagcacaag ctcttcgttt gctggggtgt ctttttcact
     8941 caatatttct cgcaccatgg gttgataggt catgacttgt ttgacatctt gatgaacgcg
     9001 gtaagcttta tagccagcaa aaaggaagac tgctagtaca agcactcttc gaattcgttt
     9061 aaacattatt tactttggat atcctcgata tttttgatta agatagagta ggttccattt
     9121 tcgttttgga taaactcaac agactcggcg tcttgataga cgttattggg aacgatgagc
     9181 tcaattccat ttgataagga gagtttttgg ttttcaaatt tctttaattg gcgactggca
     9241 tcaatttcat caaattgaac aggttctggt acggcttctt tgacttggtc aataaagctc
     9301 aaacgagccg tcagattgtt gtcaaaaagg tcattagcca atttctcagg tgacaattca
     9361 ttgctttctt ctaggttgtt gaaaatagct gatttgacct tggattgaaa ttgaaaatca
     9421 tctgtgttaa aagattcagc aattctctgg gctgtttttt ccagttcctt gatagatttt
     9481 ttaggagaaa tcttaggagc gacagcaaga agattatctg aaaaatagtt caaaaaagtc
     9541 ccgttgtact tgattcgttt ttcaatcagg tgatacttgc gactctgaag attgaccacc
     9601 aaggcctcgt cagcacccgt tccaaatcca ggcaggttat tctgagtcag cttgattgga
     9661 ttatcaactt ctcctccgag gtgggtcaag gtctcccgca gggcaattcg caagaaagcg
     9721 aaatgttcta caccttcttt agaaaattga acaaaaatca agtcattggt cttgagattt
     9781 tcagaaatgc taaactcctc tttccagaga ttagccagcg ttactgatgt ctccaacaaa
     9841 tcgtctgtaa tatgattgaa gaagggattt tcttcttcga aaatcccagt cttggcttca
     9901 tctgaataca catgttcaat ttttttacgt aggtattctt cgatttttgg agtaatattg
     9961 agaaacttat ctgctaagaa cagctcggta tcatccggac tgaactggtg aataatggct
    10021 ttcttaatat aaatgtccat aaaagtttta ttcctcgtat aatgggaagg catctgtcaa
    10081 ttctttgact gcacttctca cttcttctaa tacagcctca ttttctgaat tcttaagggt
    10141 tttaatgatg agttcagcca ctttgcgact ttcttcttca ccaaatccac gtgcagtaat
    10201 agctgctgct ccgatacgaa tcccacttgt cttgaatggt gacaaggttt cgtaagggat
    10261 tgaattttta tttagggtaa tattgacttc atccagcaag ttttgagcaa cttttccgtt
    10321 ttctacaacc ttagtcacat caacaaggaa gagatggttt tcagttccac ctgaaataat
    10381 acggaaatca gggtcttgca agaagacatc tgccatagcc ttgctgttct taattacatt
    10441 ggcagcatat tccttgaagg ctggatccaa aacttctttg aaggaaactg ccttagccgc
    10501 cacaacatgc tctaaaggac cgccctgaat acctgggaaa atagctgaat tgattttttt
    10561 agcaagttct tcgtcattgg tcaaaatcaa accaccacga ggtccacgaa gggttttgtg
    10621 ggtcgttgtt gttgtgatat gagcgtatgg aactgggctt ggatgaaggc cagccgcaac
    10681 caagccagcg atatgggcca tgtccaccat gagcttcgca ccgacagcat ctgcgatttc
    10741 acggaatttt gaaaaatcga taatttgaga ataggctgaa gcaccagcta caatcagttt
    10801 tggttttact tcttgggctt gtttcaagat agcatcaaag tctaagagtt ccgttttagg
    10861 atcaacacta taagaaacaa agttgtaggt ttgaccagag aagctaacag gagccccatg
    10921 agtcaaatga ccacctgatg ccaaatccat tcccataacc gtatcacctg gctcaatcaa
    10981 ggacatgtaa gccgcacagt tagcttggct tcctgaatgt ggttgaacat tggcaaattt
    11041 agcaccgaaa atttcttttg cgcgttcaat agcaagagtc tctacaacgt ctactacatc
    11101 agttccacca taataacggc gtcctgggta accctcggca tatttgtttg tcaagataga
    11161 cccttgagct gccataacag ccttggaaac tacgttttcc gaagcaatca actcgatatt
    11221 attttgttgg cgttcttctt ctttagcaat agcattccag agatcagcat catatgcttt
    11281 aaaatcatct ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta gtccattagt
    11341 ttgattttac aataagaaaa taaactaaaa gatgcgaata aaccgtttct gcactttatc
    11401 acaagtataa ccaacttttt cataaaatgc atgagcaccc agacgatgat tggcagaatt
    11461 taagcggata aacccataac cacatctttt ggcttcttgt tccaaccctt gtagtaaact
    11521 tttaccgata ccttgacctt gcgcttgagg tgaaactgct aaagctaaga tattaaatcc
    11581 tgctttggaa tagagtgatt cgtaaacttc agcgtggaca tatccaagta agacatgatt
    11641 agctgcatcc tcatagccaa gtaggaaatg atgggaatcc tgagacagtc tagctagttg
    11701 gctagccgtt tcctctggac taaaagtata acccaaagcc tcttggttga tgtcacatat
    11761 cgctttcaca tctgtttctt gcaaatctct tagcatttca agcctcctca aaagaaatct
    11821 ctggcaaccg agcaagaata tcttctcgtt taattgcgcc ttggcgtaag attttcacct
    11881 tgtctccaga caaatccaca atagttgaat cctgtccagt tagaaaagca tcgtcttcca
    11941 gacccagaac ctcttggtca aaatccttca gaatttgttc aaaggttaca ccacttgcct
    12001 gacctgagat attggcagac ggcccaatca agggacctgt ctctcgaatt aaatccagtg
    12061 tgatagggtg actgggcatc cgaaatccaa tagttgcaag gtcagaattt acccaatagg
    12121 gaactcggtc attggcttcg agaataatgg tcaagggacc tggcaaaaag gtctctacaa
    12181 gtttttgtag ataagctggc tgattctttg aaaagtgcaa gatgtcctcg aaagaggcga
    12241 tattgagatt gagtgcctta tctctaggac gacgtttgag ttggtaaaca tggtcaactg
    12301 ctttttcatc taaggccttg gaaaaaagac cataaacagt ctctgtaggt agaacgacag
    12361 ctccaccatt ttccaactct tgtctaatcc tgtccatcat caaccacaac catcctattt
    12421 tgaccaaatt ggtctttgag tgttcgaact cttttttcag gaagatgttt tctaaaaagt
    12481 tcgggaacac tttgaccttg cttgtatcca atttcaaggt aaatcttacc accatctttg
    12541 agatagtctt ttgcatcttc cgcaattcta cagtaaatag ctaggccatc ctcgtctgca
    12601 aagagagcta gatgaggctc cgaatacaag acattcaagc ctacctctga ctcatcttca
    12661 cgagagatat agggtggatt ggaaacaatt atatcatatt tttcagaaat ttctgtaaaa
    12721 cagtcagatt ttttaaaaaa tatttgaaga ttttgatttt tagcattttc gctagctaaa
    12781 tctaaagcct cttgagaaac atctgctgct gtcactgacc aatctggtct attttttgct
    12841 agagcgagag caatagctcc actacctgtt ccaatatcca gaactgaaag attcgtctca
    12901 agattttcag ttagaataag ctccactaac tcctctgttt ctggacgagg aatcaaaacc
    12961 cgttcatcca cctttaaatg cattccataa aaatctgcct gtccaatgat gtactgagct
    13021 ggcttgtgag ctgctagttg ctggtaaata tcttctacaa attgtttttc ttcctctgtt
    13081 gtcacctcct gctggagggc aaaaataaag tctgtaaaag atagattttt cagactacga
    13141 tagacaaaag agaggctttc cgcttcctct ccttgtctta tcaactcttc ttcaaaattt
    13201 gaaaataatt gagctaattt cattatttgt ttaattcttc tagtttttgt gtttggtcat
    13261 aaagcaccaa ggcatccaca acttcgtcca atttaccaga caaaatcgta tctagttttt
    13321 ggagggtcaa gccgatacgg tggtctgtga cacggttttg tgggaagtta taagttcgga
    13381 tccgttctga acggtcacca gtaccgattg tcgacttacg ctcagcgtct tgttcatcct
    13441 gagcaatctg agcaaagtgg tcagcgacgc gtgcacggat aatcttcata gccttctcgc
    13501 ggttcttctg ctgggtacgt tcttcctgca tctcaacctt gatattggtt ggcaagtgaa
    13561 cgatacgaac ggcagtcgca accttattga cgttctgtcc accagcacca gaggcgtgat
    13621 agatgtcgac acgaaggtct tttggatcaa tgtcgtattc aacctcttca acttctggca
    13681 taacaagaac tgtcgctgtc gaagtatgaa cacggccttg gctttctgtc acaggaacac
    13741 gttgcacacg gtgggcacct gattcatact taagcttaga gtatacagac tgacctgaaa
    13801 ccatagcaac cacttcttta aaaccaccga caccattcat agaggcttcc atgacttcaa
    13861 agcgccaacc ttgggcttcc gcatactttt ggtacatagt tagcaaatct ccagcgaaaa
    13921 gtgccgcttc gtctccacca gctgctccac ggatttcaag gatgatattc ttgtcatcgt
    13981 ttggatcctt tggaaggagc aaaattttca gtttttcttc atattcttct ttttcagcct
    14041 tggcatcttt gagttcttgc ttggccaatt cttccaagtc cgcatctccg cctgattcct
    14101 taatcatctc ttcggcatcg acgatatttt gaaggacttg tttatactca cggtaggcta
    14161 ttacggtgtc acgattggaa gcttcttctt ttgaaagctc cataaaacgc ttggtgtctg
    14221 aaacgacatc agggtcactc agcaattctc ctagttcttc ataacggtct tctacagctt
    14281 gtagttgatc atagatgttc attttttctc cttatttctc aattgttaaa tcatagattg
    14341 ctactacttc attctcggat atttccccag tttctttaaa tccataactg aggtaacaaa
    14401 atcttgcctg ttcattttct ggttcataag acaaccaaag tttattgctt aaacctgctg
    14461 gcgctgttcg aacatagtct agtactttat ccataattgg tttaaaatat ccttgatttt
    14521 gaaaattctt atcaatcata aaacgaaata gtaaataatt tccactacta attccgatct
    14581 ttttatcata agctatcatc acaaaaccta taattgcatc attatcataa actgccaatg
    14641 gagctacaaa atctccattt ttagtgtaga cgtatgcttc agctaaacta attgcgttgg
    14701 ttgcaatgaa ttgtttttga tattccttga catccaaatt taaaacatca aaataatttt
    14761 ccattgtaac atctcttagt tcaattgtca tagttttgct ccttgttaga ggttatcatt
    14821 ggcgcaaaat aatgtttacg gcaaaccgag atataggttt cattaccacc aatctggatc
    14881 tgttctccat cgtaaacggg cagtccatcc tgtgttcgca acaccatggt cgcctttttc
    14941 ttgcaatact gacagatggt cttgatttcg tcaatcttgt ctgctaaaag caagagatat
    15001 ttggaacctt cgaacaattc attgcgaaag tcatttttca agccaaaagc catgacgggt
    15061 atgtctaact cgtccacaac acgagctagg tcataaacat ggtggcgttt gagaaactgg
    15121 gcttcatcga ccaaaacaca gtaaggtttt tctggtaggt ctcggatata gccaaagata
    15181 tccgttgttt cctcaatcgc aagggcaggg cgtttcatgc caattcgact cgacacatag
    15241 ccaacaccgt cacgcgtatc cagagccgag gtcataatca caacaccttt tccttgctcc
    15301 tcgtagttat aggccacttt gagaatctca atcgttttac cagagttcat ggtcccataa
    15361 cgatagtaca actgtgccat gtttcttgct tcacgtccat ttctaaattt ttgctacatt
    15421 ctagtatatc ataattttct taagctttaa acggcaaaat gtggtaaaat ggaagaaatc
    15481 aaaactagtg gaggaagcta ttatgccatt tgtacgcatc gatttatttg aaggacgcac
    15541 gctcgagcaa aagaaagctc ttgctaagga agtaacggaa gcagttgtcc gcaacactgg
    15601 agcccctcaa tctgctgtcc atgtcatcat caacgacatg ccagaaggaa cttacttccc
    15661 acaaggggaa atgcgtacta aataagctag cttaagcaga attgcttagg ctttttcaat
    15721 ctccaagtag cattcattga agaaatatcc taaatttgtt acaatttgaa aagaaacttg
    15781 gagaatttcc aagaaaatag ctattaatta aaggaaacat tatgattaca cgtgaatttg
    15841 ataccatcgc tgctatctct actccactag gtgaaggggc tattggtatt gtccgcctga
    15901 gcggaacaga cagttttgct attgcgcaaa agatttttaa aggaaaagac ttgaacaagg
    15961 ttgccagcca cactctcaac tacggtcaca ttattgatcc tctgactggt aaagtcatgg
    16021 acgaggttat ggttggggct atgaagtctc caaagacctt cactcgtgag gatattatcg
    16081 agattaacac ccacggtggt attgcggtga ccaatgagat tctccagcta gctatccgtg
    16141 aaggagctcg gttggcagaa cctggtgaat ttaccaaacg tgccttttta aacggtcgcg
    16201 tagatttgac acaggccgag gcggtgatgg atatcatccg cgccaagaca gacaaggcca
    16261 tgaacatcgc ggtcaaacaa cttgatggtt ccctttctga tcttatcaat aatatccgtc
    16321 aagaaatcct taacacactt gcccaagttg aggtcaatat cgactatcct gagtatgacg
    16381 atgttgagga agccactact gctgttgtcc gagagaagac aatggagttt gagcaattac
    16441 taaccaagct ccttaggaca gcacgtcgtg gtaaaatcct tcgtgaagga atttcaacgg
    16501 ctatcattgg acgtcccaac gttgggaaat caagccttct caacaacctc ttgcgtgagg
    16561 acaaggctat cgtaaccgat atcgctggga caacacgaga tgtcatcgaa gagtacgtca
    16621 acatcaatgg tgtacctctc aaattgattg atacagctgg tattcgtgaa acggatgata
    16681 tagtggaaca aatcggtgtt gagcgttcga aaaaagccct caaggaagcc aacttggttc
    16741 tactagtgct aaatgccagt gaaccactga ctgcgcaaga cagacaactt cttgaaatta
    16801 gccaagatac caatcgcatt attctactta ataaaaccga cctgccagaa acgattgaaa
    16861 cttcgaaact acctgaagac gttatccgta tttcagtcct taaaaaccaa aacatcgaca
    16921 agattgaaga gcgaatcaac aacctcttct ttgaaaatgc tggcttgatt gagcaagatg
    16981 ctacttactt gtcaaacgcc cgtcacattt ccctgattga aaaagcagtt gaaagcctac
    17041 aagccgttaa tcaaggtctt gagctgggga tgccagttga tttgcttcaa gttgacttga
    17101 ctcgtacttg ggaaatcctc ggagaaatca ctggggatgc tgctccagat gaactcatca
    17161 cccaactctt tagccaattc tgtttaggaa aataagaaaa atccatgatc cttcattcgg
    17221 tcatggattt tattgtcttt attagtaatc tggtcttaag acccctgtta cagttgcctt
    17281 agttgcttcg tagtcgccat ctacgacaac cttgataatg cgtttggcat cttcttctgg
    17341 tgctggaaca agaggtagac gagtgggtcc agcttcaaat cccatatagt taagaattgc
    17401 cttaactgga gcaggacttg gataagagaa gagagcatta accttaggaa tgaatttacg
    17461 ctgaattgct gcggctttct tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat
    17521 ttcatcccca tttgtatgag aggcaacaga aataacccca tccgccccaa ggttcatggc
    17581 atggaaagca tctccatcct cacctgtata aatcaagaac tcttcaggct tgtgctcaat
    17641 caagtaagcc atattagcca agctagtaca ttctttgaca ccgataatat ttggatggtc
    17701 agccaagcga agcatggttt ctggagtcaa ttcgacaact acacgccctg gaatgttata
    17761 gataataatt ggtaggtcag aagcatctgc aatagtctta aagtgctgat acatcccttc
    17821 ttgagaaggt ttgttgtagt aaggaacaat agcaagccca gctgcgaaac caccaaattc
    17881 cgctacttct ttgacaaact caatagagtc acgcgtatca ttagtaccta cacccgcaat
    17941 caaaggaacg cgtccattga caaccttttg tacagccgca aacaactcca actcctcatc
    18001 gtgggtcaaa gttggactct cagcagtcgt tcctgcgaga agaattccat ccgtatgatg
    18061 ggccaataaa tgctcaatca aggctggaat agcatcaaag ttaatagaac catcctcatg
    18121 aaagggggta ataaaggctg taatgatttt acattctttt aaatcttgat aagacatgaa
    18181 aacacctctc tatttcaaag aaggagttca tctgaactcc taaacgatat gactatttta
    18241 attcaaattt caattcggct gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa
    18301 tctgaactga gttccaagca gcacctttga gaaggttatc tgaaacaacc cacatgtgaa
    18361 ttcctttttc tgcatccaag tctttacgga tacgaccaac aaaggtatca cgcgaaccaa
    18421 ctgcattgat agcttgagga tagatttgat gagctacatc atcttcaaga acagcacctg
    18481 ggaaggctgc gatagctgct tttacttctt cgattggagc cacttctttt gtttcgatat
    18541 aaacagactc agagtgagct gacaagactg gaatacgcac acatgttgca gatactgcaa
    18601 tgctatcatc ttccataatt ttcttagttt ccttggtcat cttcatctct tcgtaagtgt
    18661 aatcattgtc agtgaagaca tcgatttgtg gaagagcatt gaaggcgata ggataatgtt
    18721 tcttgtcacc acctgaaggc aaaatttccg catgcaaatc acatggtttc acaccatcat
    18781 tcaagacctc acgaagttca cgttgtgtct caagaattgc tcccatacca gcacctgaaa
    18841 cggcttgata agttgaaaca atgatacggt ccaagcccca tttttggcga accggctcaa
    18901 gagccaccat catttggatt gttgaacaat tagggcaggc aatgattccg ttgtgagcat
    18961 caagtgcatg agcattgacc tctggaacaa ccaaaggaac atctggattt tgacggaaat
    19021 aagatgtatt atctactact accacgccag cttttactgc gtatggtgca tacttagctg
    19081 atgtagaact acctgctgaa aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg
    19141 tttcttcaat tgtaatatct tgatctttaa atttcaatga cttacctgct gaacgtgcag
    19201 aagcaaggta acggatttta tcgattggaa gtgttgattc ttccaacatt tttatcatct
    19261 gagcaccgac agcacctgtc gcgccgacta cagcaactgt atatcccata aataacctct
    19321 ttcggaattt tctaaaaatt tctataatag aagtattata ctactttttc catgaattgc
    19381 aaagcttttt cattattttt tggaaaataa aaatcccagt cgctagacta gggactaaga
    19441 ggcatcttca tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga
    19501 cctccttatg ctcaatagta gtccgaagac tacctatcga ctcatcgcat attctatatt
    19561 actagagata cttgattttg tcaataagaa attttttcga tcgagtataa caaaaaactc
    19621 ttgtattcaa gagtttccct atacatatca tgctaattgc cgggattgaa ccggcgacct
    19681 catccttacc atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac
    19741 tataatcaga aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa
    19801 gaactaccta gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa
    19861 taataatcgc tccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa
    19921 ggaagaatgg taattctgct acaatattta actctgcagc gatagtaaac atggaaattg
    19981 aaaagaggat tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct
    20041 tgctatattt tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac
    20101 caacaaagac atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa
    20161 ctccgatgat gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa
    20221 actgataagc accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga
    20281 tagcagcgac gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc
    20341 ctttggcggt tatccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgat
    20401 tcattcaacc ttactagtat agcacaatag cctgctttat gctatactta aagcatgaaa
    20461 attcctattc aaaaattttt taacaatgaa atcttagcct atctcttttt tggccttgcg
    20521 acaactctag tttcgattct ctcacgacta gtcatttatc aactaagtca tcaggaactc
    20581 cttgctacgg ccttggcaaa tattatcggt atcttatttg cctttatcac aaatgatacg
    20641 attgtattta agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct
    20701 cgcctttcta cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct
    20761 cacatcatag ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata
    20821 attgcacaaa tattcattat tatcatcaat tatatcttga gcaaggtcta tatttttaga
    20881 aaataatgct ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga
    20941 aacacgaaac attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga
    21001 ggaaatgtta ttgaccttgc tgtcggtgtt gtcattgcct ctgcttttgg tgctatcgtt
    21061 acttcacttg taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct
    21121 aaagtcgaac gtatcgctca actttcttgg catggagtcg gctatggtaa ctttttaagt
    21181 gctattatca attttatctt tgtgggtacc gccctcttct ttattatcaa gggcattgaa
    21241 aaagcacaga aactgactgg cataaagaaa gaaaaaactg ccgaaaaaaa accaaccgaa
    21301 ttggaagtcc ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc
    21361 tagcgcaaag ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc
    21421 atttttttga taagataagg catcttaata ttctcccgcc cttttttctc aatcagtttt
    21481 ttcacaaatt ctggcatttg taaatcttca gattcagcta aaatgttttt cgtctcgtct
    21541 gaaggaacta actcatcaaa ggtctcttct tctgggagaa attccttaaa ctcttgattt
    21601 tcattgactc taactgtatt gaccaaagca tcaatcaaac gagaatctgt atttggcatt
    21661 ggtggacgat ggtagtttac cccaaattcc tgacataaat cataacattc cacatcattg
    21721 tcaaacaaga cctcaatatg ctcactgatg aaactaatag gtacaaaaat ataatggtct
    21781 ggatgttctg tctgttctct gagatactcc aaaacatctg gtttaatcca tggaatacca
    21841 atatcactct cactctgcca agtgttggta tattgttctg aactcaagcc cagtttttca
    21901 gcgactagct tgctattttc gaaaatttgg tctatataag gatctccaaa gtccaaggca
    21961 aaaataggca cactatgggc tgaaaagatg actttaaagc tgtcttgctt tacttcttct
    22021 tttaaaatct tagcaatttc atctgcccaa tagtttaaga gcgcttcttc ctgataccag
    22081 tccttaatga ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca
    22141 gagtagaaag aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct
    22201 tccatttgac cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca
    22261 ctgtattcat tccccagcct agcttctacc aaggcaacct cttgacgggt aattttttgc
    22321 agaggcgtgc ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg
    22381 ggtctcatcc cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct
    22441 tctggtgaac cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt
    22501 ttttatcaag tttattttat cattaattca tcgataagta aacgctagca tagggacatt
    22561 ctcaatcttc tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc
    22621 aaaaggagtt ttttatgact tatccaaatc tcttggaccg cttcttaacc tacgttaagg
    22681 tcaacacgcg ctctgatgaa cactctacta ctactccaag tacacagagt caggttgact
    22741 tcgcaacaaa tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat gtttactatc
    22801 taccgaatgg ttttgctatt ggaaccttgc cagccaacga tccgtcttta acacgtaaga
    22861 ttggttttat atcgcacatg gatactgctg attttaatgc tgaaggagtc aatccacagg
    22921 taattgaaaa ctacgatggt ggtgtgattg aactagggaa ttctggtttc aaactcgatc
    22981 cagctgactt caagagtctt gaaaaatatc caggacaaac gctcatcaca acagatggaa
    23041 caagcttgct aggtgctgat gacaagtcag gaattgctga aattatgaca gccattgaat
    23101 atctaactgc tcatcctgaa attaagcact gtgagattcg tgttggtttt ggtccagatg
    23161 aagaaatcgg tgttggtgcc aataaatttg atgcagaaga ttttgatgtg gattttgcct
    23221 acactgttga tggtggtcca ctaggtgaac ttcagtacga gactttctca gccgctggtg
    23281 ctgaattgca tttccaaggc cgtaatgtcc accctggtac tgccaaaggg cagatggtca
    23341 atgcccttca gctagcaatt gattttcata atcaacttcc agaaaatgac cgacctgagt
    23401 taactgaagg ttaccaaggt ttttaccatc taatggatgt gacaggtagt gttgaggagg
    23461 cgcgtgcaag ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat
    23521 ccatgcaatc tatcgctgat aagatgaatg aagaacttgg gagcaaccgt gtcactctca
    23581 acttgacaga ccagtactac aatatgaaag aagtcattga aaaagatatg actccaatta
    23641 ccattgctaa agccgttatg gaagatctag gtatcacgcc tattatcgaa ccaatccgag
    23701 gtggaacaga cggctctaag atttccttta tgggaatccc aactccgaat atctttgcag
    23761 gtggcgaaaa tatgcacgga cgttttgaat acgttagcct tcagactatg gaacgtgcag
    23821 ttgataccat cattggcatc gtacgtagct tataaaagct aaaaagacga ggtagctcag
    23881 ctacttcgcc tttcttttta ttctactggt ttttcttgat ttccagtagt tgtagaagat
    23941 tctgttgttt tattttctga agttgattca gcaggtttag aatctcttgt attgcttggt
    24001 ttgttttcgt cgctagcagt ttcaatgtta gattctgcag ttgcgtttgg ttggttctca
    24061 gcactggtgt tatcaccatt tgcttcagca tttcttgctg gacttgtttc ttcacttgcg
    24121 ctagcttttg actggatttg atgattcaaa actagaatag cttttgtcga ttcaagtaaa
    24181 gctgttttgt ctttactctt agcagaaagt tgatctaata atgcatccac cttatcaaag
    24241 tccgcatcag atccattatt actttctaaa taagagtgaa gcgacatgag aatatcgtag
    24301 agtttttgat agagtacaag tgtctgagga tcttgctcag cattttcctt ttcttgttga
    24361 agggcgctag cgatacgagt caaaacatct tttacctgac tgtttacttc atccaagtct
    24421 gcatcagcct tgtttgtggc agcttttaga ttttctactt cttctgccaa ggattgtctg
    24481 attccttctt catggatttg ttccaagagt tgatttgcct tgttcaaaag actttctact
    24541 tcttccttgc tatctgtcgc agattattgg ttgctatcta ccatgtactc ctaaaacagg
    24601 agagttataa tccaagatta caaggcctta cagaaataag aaatccagat aagacaatgt
    24661 tcgtccaaga cgctattcgc ttcgcacagc agcacggatt caatatgctt taattttaaa
    24721 gtttaggtgt caagacctct ttttagtgtg cccaaaattt agagaagtaa tcaatcaact
    24781 aacttttatt tttttcaaac tttcagtaaa ctgacctaaa gctaactcaa tctgtctttg
    24841 tagatgcttc tgctatcagc tagaagttga tctacttttg ccaagactgc cttctcatca
    24901 aaagttccag gttgatagtt ggattgcagg gatggaatct tgtttttcaa agccgcttca
    24961 tatcccttag tttgaacctt gatgtagtga ttgtggtcgc catgaggaat cacaaaacct
    25021 tctgaatctt cacttataat tcgattggca tcaaaaacca tgaccatctt cttcctcatg
    25081 gtggacatgt agtgacggat tacttaatac agaactagaa gaacttccta cctcttccgt
    25141 gttagagtgt gatgggggat tgttaagaga tgacttagga atatagtgat agtgttcccc
    25201 atgtcttact atataagcat cacctatatc tctgacaata tcattagggt taaagacata
    25261 accatcatct actgcagaaa caccattatt cggtgtcacc ggcaaagatt gactgagagc
    25321 tgtagtattc cctgataatt atacttttgc gactgctaat tcacctgccg acaagtcact
    25381 ctcaggaatg aaatgatagt gaccaccatg tggtactatc gtagattgaa atagaatatg
    25441 agcaaattga taaggggatt ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg
    25501 ctattctaaa ttcaactcac tatatataac catcatcggt agtataacgt ccctgtaatt
    25561 ttgctacaga tacttctgca ctagctcctt tatcgtcttt accatgttct tgtttttggc
    25621 gattgatttc atcttttgtt cgtacatttt ctgcatgagc ttgatcttta aggtaaacat
    25681 aatactttcc atctccctta ataatatatc ctcccttaac ctaactgacg atatcttgat
    25741 ctttcggctg atagttgggg gctttcatta gtagctcttc actaaagagc gcatcaaaag
    25801 gaactttacc attatagtag tgataatgat cgccatgaga agttacataa ccttgatctg
    25861 taatcttaat aacaatttgt tttgcttgaa ttccttcttt ttgactaacc tagtctggag
    25921 tcaaattttc agtcttctta gtgtctttat tactgtttac atatgaaaca cgatttttat
    25981 ctgtattggc ctgttagcta tgttggttca gagcataaac acacagactt aaggaaagga
    26041 taacaacaga tccagctgct atat
//
LOCUS       DAVMBH010000027        25797 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVMBH010000027 DAVMBH010000000
VERSION     DAVMBH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.027"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..215)
                     /locus_tag="VYP30_001283"
     CDS             complement(<1..215)
                     /locus_tag="VYP30_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEV1808275.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAA"
     gene            complement(284..553)
                     /gene="blpJ"
                     /locus_tag="VYP30_001284"
     CDS             complement(284..553)
                     /gene="blpJ"
                     /locus_tag="VYP30_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1808276.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1020..1217)
                     /gene="blpI"
                     /locus_tag="VYP30_001285"
     CDS             complement(1020..1217)
                     /gene="blpI"
                     /locus_tag="VYP30_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1808277.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1499..2086
                     /locus_tag="VYP30_001286"
     CDS             1499..2086
                     /locus_tag="VYP30_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1808278.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2013..3656
                     /locus_tag="VYP30_001287"
     CDS             2013..3656
                     /locus_tag="VYP30_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1808279.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLIMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3667..5028
                     /locus_tag="VYP30_001288"
     CDS             3667..5028
                     /locus_tag="VYP30_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1808280.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5085..5213
                     /gene="blpC"
                     /locus_tag="VYP30_001289"
     CDS             5085..5213
                     /gene="blpC"
                     /locus_tag="VYP30_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1808281.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(5284..6624)
                     /locus_tag="VYP30_001290"
     CDS             complement(5284..6624)
                     /locus_tag="VYP30_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1808282.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMIGYMVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(6638..7375)
                     /locus_tag="VYP30_001291"
     CDS             complement(6638..7375)
                     /locus_tag="VYP30_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808283.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(7380..7718)
                     /locus_tag="VYP30_001292"
     CDS             complement(7380..7718)
                     /locus_tag="VYP30_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808284.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7994..8323
                     /locus_tag="VYP30_001293"
     CDS             7994..8323
                     /locus_tag="VYP30_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1808285.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKTETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8491..9540)
                     /locus_tag="VYP30_001294"
     CDS             complement(8491..9540)
                     /locus_tag="VYP30_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808286.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9537..10268)
                     /locus_tag="VYP30_001295"
     CDS             complement(9537..10268)
                     /locus_tag="VYP30_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808287.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10336..10746
                     /locus_tag="VYP30_001296"
     CDS             10336..10746
                     /locus_tag="VYP30_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1808288.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10756..11043
                     /locus_tag="VYP30_001297"
     CDS             10756..11043
                     /locus_tag="VYP30_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808289.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(11377..12513)
                     /gene="dnaJ"
                     /locus_tag="VYP30_001298"
     CDS             complement(11377..12513)
                     /gene="dnaJ"
                     /locus_tag="VYP30_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1808290.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12915..13271)
                     /locus_tag="VYP30_001299"
     CDS             complement(12915..13271)
                     /locus_tag="VYP30_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1808291.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTRY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(13273..15096)
                     /gene="dnaK"
                     /locus_tag="VYP30_001300"
     CDS             complement(13273..15096)
                     /gene="dnaK"
                     /locus_tag="VYP30_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1808292.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15576..16109)
                     /gene="grpE"
                     /locus_tag="VYP30_001301"
     CDS             complement(15576..16109)
                     /gene="grpE"
                     /locus_tag="VYP30_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1808293.1"
                     /translation="MAQDIKNEEVEEVEEVQEEEVVETAEETTPEKSKLDLANERADE
                     FENKYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDV
                     KKGLGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKG
                     YKLHDRILRPAMVVVYN"
     gene            complement(16136..17170)
                     /gene="hrcA"
                     /locus_tag="VYP30_001302"
     CDS             complement(16136..17170)
                     /gene="hrcA"
                     /locus_tag="VYP30_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1808294.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17334..17843)
                     /locus_tag="VYP30_001303"
     CDS             complement(17334..17843)
                     /locus_tag="VYP30_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1808295.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18450..20783
                     /locus_tag="VYP30_001304"
     CDS             18450..20783
                     /locus_tag="VYP30_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1808296.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20796..22259
                     /locus_tag="VYP30_001305"
     CDS             20796..22259
                     /locus_tag="VYP30_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1808297.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            22259..23827
                     /locus_tag="VYP30_001306"
     CDS             22259..23827
                     /locus_tag="VYP30_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1808298.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            23884..24681
                     /gene="psrA"
                     /locus_tag="VYP30_001307"
     CDS             23884..24681
                     /gene="psrA"
                     /locus_tag="VYP30_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1808299.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            24692..25300
                     /locus_tag="VYP30_001308"
     CDS             24692..25300
                     /locus_tag="VYP30_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1808300.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(25248..25793)
                     /locus_tag="VYP30_001309"
     CDS             complement(25248..25793)
                     /locus_tag="VYP30_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1808301.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         8323 a         5081 c         4624 g         7769 t
ORIGIN      
        1 gctgcatagg ctacacctcc aagtatagct ccacccgcag caccagttgc tgcaccttgc
       61 catgttcctg ttttaatgcc tagttgaaga cctcttgctg ctgctcctcc aacacctgct
      121 ttggcaaaat ctccccaatt gcatccgcca ccttcaacgc aagcaagcat ttcagtatcc
      181 ataacagaaa attgtgacat catttttgta tccatgacaa atactccttt tttaaaaaac
      241 taaaataaat cagaatagaa tcctcataat tttactataa gtcttaccaa cttagtccca
      301 atttatcacc aaccatacct cctaagcatg ttaatccacc cccaattgca ccaatgtgtg
      361 ctccaacaaa tgcaccagca agtccagcta ctcctaaagt ggccaaacct gctccagttc
      421 caccagttat aattcccgta gtgactcctg taatcagtgc attttgacaa tcagtggagc
      481 tatacccccc ttcaactttc gcaagcattt cagtatccat aacctctaac tgtgacaaca
      541 tttttgtatt catgatgaat acctcctttt tattttcaat ttgttaccaa agtcttaaat
      601 tcaataaaca aatagatttt ttatagtatc tttttgattt tcttaaaaaa gtatatacgt
      661 ctactatctt cttaaaggta gcagtaccta ttttttagtc taagatttca ataatcttga
      721 gtatctaaaa tatcttaatt tcgttattct ccttgcaata aaaagtttta ctatactatt
      781 tattaacttg cagaaagcaa aaaatattag taaataatag tttatagtta agttttttat
      841 tcctaccaat ccatcaacta agtaaagcat caacgattac ataaacgatt gataatataa
      901 ttaaaatttt gctaactatc ttattctcat cattcttaga taactttgat attttgtaag
      961 taagtaaata agacagtaaa ttaatagcga taataatact atatttaaga atcataatct
     1021 tacaaagagg acataattcc tgaacctaca caaataagtg ttgctgctcc cccagttatc
     1081 ggaccagtcg cagcagctaa tagtactgct ccaatacaac caccgattgc agatcctaaa
     1141 ttgcctcttc ctccactaac tatttcgagt tcttcattat ccataacaga aaattgttcc
     1201 atcatttttg tattcatgac aaatactcct tttttctttt tttatttttg tcttgttgta
     1261 actttgataa gtttagtata tcatcgtttt ttaaaatttt tcatccagat cttgaattgt
     1321 catcgaaacg tcttgaatta gcttttttat tttaagccac ctctaaatgt ttaaaaaaaa
     1381 taatttctaa tcactttttt accattcagg aagttttaat gactattcaa gatttcataa
     1441 aatatgaact tagttttatg acataataga cctatccact atatgaaaag aattgccaat
     1501 gacttcttat aaacgtacat ttgttcctca aatagatgcg agagactgtg gtgtcgctgc
     1561 cttagcctcg attgctaaat tctatggttc agatttttct ctagctcact tgagagaact
     1621 tgcaaagacc aataaagaag ggacgactgc tcttggcatt gtaaaagccg ctgatgaaat
     1681 gggctttgaa acaagacctg ttcaagcaga taaaacgctc tttgacatga gtgatgtccc
     1741 ctatccattt atcgttcacg ttaacaaaga aggaaaactc caacattact atgttgtcta
     1801 tcaaacaaag aaagactatc tgattattgg tgatcctgac ccttctgtaa aaatcactaa
     1861 aatgtcaaaa gaacgctttt tctatgaatg gactggagta gctatttttc tagctaccaa
     1921 acccagctat caaccccata aagataaaaa gaatggtcta ctaagcaagc ttccttcctc
     1981 tgattttcaa acaaaaatct ctcattgctt acattgttct ctcaagctta ttggtcacta
     2041 ttatcaatat aggtggttct tactatctcc aaggaatctt ggatgagtac attccaaatc
     2101 agatgaaatc aactttagga atcatctcag ttggtctggt tatcacctat atcctccaac
     2161 aagtcatgag cttctccaga gattatctcc taaccgttct gagccagaga ttaagcattg
     2221 atgtgatttt atcctatatt cgccatattt ttgaacttcc catgtctttc tttgcgacac
     2281 gtcgtacagg agaaatcatt tcacggttca cagatgctaa ctctattata gatgccttgg
     2341 cttctaccat tctttctctt tttctggatg tttctattct gattcttgta ggaggcgtct
     2401 tactggcaca aaaccctaat ctcttccttc tttctcttat ttctattcct atatacatgt
     2461 tcatcatctt ttcttttatg aaaccttttg aaaaaatgaa ccatgatgtc atgcaaagta
     2521 attctatggt tagctctgcc attatcgaag atatcaacgg gattgaaact ataaagtcgc
     2581 tcacgagtga agaaaatcgc tatcaaaata tagacagcga atttgtagat tatttggaaa
     2641 aatcctttaa gctcagtaaa tattctattt tacaaacgag tttaaagcag ggaacaaaat
     2701 tagttctgaa tatccttatc ctatggtttg gcgctcaatt aatcatgtcg agtaaaattt
     2761 ctatcggtca gctgattacc tttaacacac ttttttctta ctttacaact cctatggaaa
     2821 atattatcaa cctccaaacc aaactccaat ctgcgaaggt cgctaataac cgtttgaacg
     2881 aagtctatct agtcgaatct gaatttcaag ttcaagaaaa ccctgttcat tcacattttt
     2941 tgatgggcga tattgaattt gatgaccttt cttataagta tggttttgga cgagatacct
     3001 taacagatat taatctcacg attaaacaag gagataaggt tagcctagtt ggagttagtg
     3061 gttctggtaa aacaacttta gccaaaatga ttgtcaattt ctttgaaccc tacaaagggc
     3121 atatttccat caattatcag gatattaaaa acattgataa aaaagtcttg cgccgtcata
     3181 ttaattacct accacaacaa gcctatatct ttaatggctc tattttggaa aacttaactt
     3241 tgggcggtaa tcatatgatt agccaagaag atattctaag agcttgtgaa ttagctgaaa
     3301 ttcgtcaaga cattgaaaga atgcctatgg gctatcaaac tcagctctct gatggagctg
     3361 gtctatcagg aggacaaaag caacgaatag ccctcgctcg tgctctttta actaaatctc
     3421 ctgttttaat actagacgaa gctactagcg gtcttgatgt cttgactgag aaaaaggtta
     3481 tagataatct tatgtctcta actgataaaa ccattctctt tgtagcccat cgtctcagta
     3541 tagccgaacg aaccaaccgt gtcattgttc ttgaccaggg gaaaatcatt gaagttggta
     3601 gtcaccaaga gttaatgcag gcgcaaggtt tctaccatca tctattcaat aaataaggag
     3661 aatgtcatga atcctaatct ttttagaagc gtcgagtttt atcagagacg ttaccataac
     3721 tatgcgacag tgttcattat acctctttca ttactattta ctttcatctt gattttctcc
     3781 cttgttgcca caaaagaaat tactgttact tcccaaggag aaatcgcccc tacaagtgtc
     3841 attgcctcca ttcagtcaac cagtgataat cctatcctag ctaatcattt agtggcaaat
     3901 caagtagttg aaaaagggga cttactcatc aaatactctg aaacaatgga agaaagtcag
     3961 aaaactgcct tagcaactca attacaaaga cttgagaagc aaaaagaagg acttggaatt
     4021 ttgaaacaaa gcttagaaaa agcgactgat cttttttctg gcgaggatga atttggctac
     4081 cataatacct ttatgaattt tactaaacaa tcccatgata ttgaactggg tatcacaaag
     4141 actaacaccg aagtttcaaa tcaagctaat ctttccaata gcagttcatc agctattgaa
     4201 caagaaatta caaaagttca acaacaaatt ggagaatatc aagagttgag agatgctatc
     4261 ataaataaca gagcacgctt accaactggc aatccgcacc agtcaatttt gaatcgttat
     4321 cttgtagcct cacaaggaca aacacaagga actgcagagg agccattttt atctcaaatt
     4381 aatcaaagta ttgcaggtct tgaatcatct atcgcaagcc tcaaaattca gcaagctggt
     4441 atcggaagtg tagcaactta tgataacagt ttagcaacca aaattgaagt actccgcact
     4501 cagtttttac agacagcctc acagcaacaa ctaactgtgg agaatcaatt aacagaatta
     4561 aaagtacaac tagatcaagc cacacagcgt ttggaaaaca ataccttaac ctccccaagt
     4621 aaaggtatcg ttcatctgaa cagcgaattt gaaggtaaaa atagaattcc aactggtaca
     4681 gaaattgctc aaatattccc tgtcatcaca gatacaagag aagtactaat cacttactac
     4741 gtatcttctg actatctacc tctactagat aaaggacaaa ctgtaagatt aaaactggag
     4801 aagattggaa atcacggcac caccatcatc ggccaacttc agacaattga tcaaactcct
     4861 accagaacag agcaaggaaa tctctttaaa ttaaccgctc ttgcaaaact atctaacgag
     4921 gatagtaaac tcatccaata tggcttacaa ggtcgcgtca ctagtgtaac tacaaagaaa
     4981 acatattttg attatttcaa agataaaatt ttaacccatt ctgattaatt ttcagataac
     5041 actctataac tatttattat cttatcaaaa aggagaatca taacatggat aagaaacaaa
     5101 acctaacttc atttcaagaa ctaacaacta ccgaactcaa ccaaattaca ggtggaggat
     5161 tgtgggaaga tttattatat aacattaata gatatgctca ttacatcaca taagaacttc
     5221 atcatccaat acaactataa aaaaataaga ccgagaaaca agtactctcg gtcttatttt
     5281 tcatcattct gtatgtatca cagtaagtac ctgacgaaag acttgatttt gacaggtggt
     5341 atttagactg gtattaggat ggctttccac aatcttcatg acggtataga gaccaactcc
     5401 tctctcctcc cctttagaac tggctccaaa ggagaagatt tcagaaatat cgatgccctc
     5461 ttctttgatg gagttttcga tgataaaggt ctcctgtgct ccatttttta aaaaggcgat
     5521 tgaaacatga ggttgactag cttccacact ggcttcaata gcattgtcac aaaggataga
     5581 cacaatggtt agaaaatcaa gtagactcat cccctcgacc tgaatctcct caggaacttc
     5641 gacattaaag acaatgttct tatctctggc ttttaaaaat ttccctgcta gaagactttt
     5701 gagggcttta tcacgaatat ttaccaatct gcccaggtca tatttattgt tctgcaattt
     5761 ctgactggaa tcctttaaga cggagccata gacctctttt atctgctcca tatcctcctc
     5821 ttcaatgccc agacgtaagc tagtcaagag gttggtataa tcatgacgaa agctccgtac
     5881 ttccttgtaa agctcctcta tatgccgact atagcgttcc atatctctat agcgcagggc
     5941 ctgctcttgt tccaatctct catagagttt ttccttcaaa taggtatcca atttcttgat
     6001 aacccccata aaaaagagta ggtaaaagac taggatgaga tggcgaacag tctttgattg
     6061 aatactttgt tcatattcaa aaaaagacag actttccatg actagatagt agccacccat
     6121 tatccagtta atctgagtca gggacttttg aaaggcttta tcgagaatct cctttctcaa
     6181 gctagtaaaa tcgtagtcca accatttcaa aaaagctaga gaaatgaaga aattgaaaat
     6241 tattatacat aacccagtaa atgagtagcc atcatatact tgcccttgtc ccaaaaatgg
     6301 aagcacaaaa taggagactc ctctataaaa gagattcacc aatatcattg gaaagagacc
     6361 ataaaagaaa aggagttttt taggaagccc tctcaataat aagaaagata agcctatgcc
     6421 gtacaagggt tccataaaat aagataggta aacatttcct accatatagc caatcatcac
     6481 aaaaacaaag gccaacagta tcttaaaaag aaaggcctta aaaatcctct cgaaagtaag
     6541 atcaattcca tccaccttaa agaaaatgac aatttctagt ccattagtaa caagtgtata
     6601 caacaatatc caagcaatgt tcataaattc tcctagctca gtgtaattta ttgatggcct
     6661 cagacacttc cctgacctta taacgggcga ttagacaact tccaccattg ggaaagaaaa
     6721 gcagtttttc tttcttatcc aaatgcacca catttgcagg attgatgaga aaagagcggt
     6781 ggcactgcaa gagacggggc tcctgcttga aaacctcctc taaactcgct gtaaattcca
     6841 gcctgtctgt cttggtatag agaataacac gatgggctct gggcgacgtt tcgagatagt
     6901 aaacctcttt aaaaggatac tgaaattggg caaattttga tttaaagtaa aagcaatctt
     6961 ccgccagact tttactatct tgactattgg catagaggag ggctgtctcg atccgagatt
     7021 caaactcctc tgctgacaag gccttatcaa tgtagtccaa agcagacact tggtagcgaa
     7081 aagacagggg cataaactcc gagtgagtcg tcacaaagac aatcagggca taaggatccc
     7141 gatcccgaat ctttctagcc acttccagtc ccttcatctc ttcatttcga atctcaatat
     7201 ccaaaaagaa tagctgatgg gcccccttct catgcacttc agccagcagt tggtccggct
     7261 tgccaaatac ctcaaaagag ctaggaatga tatgatgtgc tttcaaaagt ttctcaatcg
     7321 tcgtttcaat tctagtctgt tgggaaaaat catcctctaa aacaaatatt ctcatcttct
     7381 tactctccct ctttcaacca tttttgacga atttctctat agcgacgtct ggcatacttg
     7441 acagcgtatt gaccttcttc tccgagaaaa aggattcttt cttgaaaatc aatcgatttt
     7501 aatttatcaa gattaaccaa acaatttcga tgacatctca tcaaggtttc cccacattgg
     7561 ttctcaagat tacttaaatt ttgaagcata ttaaaactag cttcttctgt aacaatctgt
     7621 acggtatggg ctttagttgg atgtgtttgg atatagtaga tatcgtcgat gtttacttta
     7681 tagactgttt tctgcgtctg aataatcata tatttcattg gattctcctc ctaagaaaag
     7741 aataacagaa aaggtctagc ccaagcacac ccaatcctaa acagtctttg aaaactccta
     7801 aaaggattat tttctacaac atcatgatga gcttacaact attttatcat aaaattcact
     7861 cagcgcaatt caagacattt caatgacaat taaagatttg aataaaaaaa aagaattaaa
     7921 agtgataaac taacagtatc aaaacacagt tgccagaagt aagactggca cccagattaa
     7981 aggaggcatt cccatgacag atacagaccc catcaaaaga gctcatactt tgattactga
     8041 cttaaacaaa gcctaccaag catgcaaaca ggcaagcgct gacgacgtcc gctttcagga
     8101 gcaattaaac tctattcttg gttttctagc caagactgaa acagtggata atcgattctt
     8161 gattgaacta gaaaaatttt accagacttc cagtcttctc atgggactca gcgctcttga
     8221 tccagatgct ccaactcgcg ccgcttggcg ggcctatgac cgcttccact ttgaccaagt
     8281 caagaccaag ttaatactca atgagaatca aagagcaaac taggaagcta gccgcaagct
     8341 gtacttgagt acggtaaggc gacgctgacg tggtttgaag agattttcga agagtataag
     8401 tctctacgga ccaaccatta tcctgtagta acaaaaaaga agctgagaca aactgaactc
     8461 aacttctttt ttagtgtcgt atcagcaatg ttagtcctgc atctgacgtt ttacctgata
     8521 aggcaaatac aagactagta aaaccaaacc agctcctagt aaggctagaa gggctagttt
     8581 ttcttggaag gtaatcaacc caacaactaa ttccacaagt aaaacaaaac tggtcaatcc
     8641 tcgaactacc tcctgtaagc ctttttcctt ttgccccttg tccagcggaa agagttgggt
     8701 caaatactgg tagtcaaagg catgatagag ggccagcaac tggaagagca agaggtagtt
     8761 aaagagaact accactgctg tcgcaatcca agcttgctcg ataaaaacct gcgccagtac
     8821 ggaaagtaag agaagacgaa gactgagagc aaagaggtcg ccatttcgca gataagaacg
     8881 cagatagaga ttttgccaaa tcttcccagg caccttctga acagccttta agataaagtc
     8941 cagataggca cgacgcttga cactgtttga aattcccttg acctgcgtaa agagggcaaa
     9001 gaaacgaagc aagacttgct tacgcttgct ttcttgagaa ataagatagt cccagtccag
     9061 tccagtttca gtgaaaaatt tgctggcctt ttgacgaaag tggaaatatt ttcctacccc
     9121 caataaaagc acatagagca gaaaaactgg caagccataa cccattgcta aaaacaaggg
     9181 cgcaaataac agcaagaaaa gggtctgtac aaagagccaa aagactaggg aaatgccagt
     9241 ttgacgcttg agatggagct tgatttcctc ttctccaact aagagaaaga gcttgtctgg
     9301 agcctccata taggtggcaa ttcctcccca aagtaaaagt aaaacagacg taattcctac
     9361 aaacaaaaga ataggccaat gattttcagg aaaatgttgt aagagttgac tgtactggta
     9421 ggctagaaag cccaacagga caagcaggaa taagacaaag tggtcattga gcacatagcg
     9481 cagataacca agacactcct tacgaaaggc ctgctttctc tttaaaaaca agtctttcat
     9541 aggtcctcct cttttgtcag agccaagtaa atatcattca aactagcctc aggcatatca
     9601 aaggcttcgc gtagttgcag gagattgcct ttggcacgca cctctccctt gtgaagaatg
     9661 acaaaggcat cacacatctt ttccgccgaa tccagcacgt gggtactcat gagaatagac
     9721 ttgccctttt gcttctccac ttccaaaagc tgaatcaaat cagaaatagc cagcggatca
     9781 agaccaagga aaggctcatc cacgatgaaa agacttggat ccaccacaaa agcacagata
     9841 atcatgacct tctgcttcat cccttttgaa aaatgaacag ggaaccagtc taatttctgt
     9901 tccagacgga acatctttaa caagggctct actcgttcga aagccacttt ttgctcaata
     9961 ccataagcca tagcaaccgt ttcgatatgc tctctgaggg tcaattcctc atacagacta
    10021 ggcgtctcag gaatgtagcc aatctgcttg cggtagctag tcgcatctcc ttgcagagtc
    10081 aggccattga tattgatgga gccactataa ggtgccaaca gaccgataat ctcattgatc
    10141 gtcgttgatt tcccagcacc attgagacca atcaaaccga ccaactgccc actttcaaca
    10201 gtaaaggaca catctttcaa aacaggaaca tgaacatagc cacctgtcag gtttttaatt
    10261 tctaacatat tttctccaaa tctggtataa tgtagctata ttatatcaaa attcagtaca
    10321 gtagaggtag attttatgtc agattgcatt ttttgtaaaa tcatcgcagg ggaaattcct
    10381 gcttcaaaag tatatgaaga tgagcaggtc cttgcctttc ttgatatctc tcaagtaaca
    10441 ctaggacaca ccttggtcgt gccaaaagaa cactatcgca atcttttgga gatgaatgct
    10501 acgagcgcca gccaactctt tgcccaagta ccaaaagtag ctcaaaaagt catgaaagtc
    10561 actaaggctg ctggtatgaa tatcatttcc aactgtgaag aagtcgctgg tcaaacagtt
    10621 tttcatactc acgttcacct tgtgcctcgc tacagtgctg acgatgacct caagattgat
    10681 tttatcgccc acgaaccaga ctttgacaaa cttgctcaag tcgctgaaac catcaaaaac
    10741 gcttaaggag ttgctatgaa attatccaac ctactgctat ttgcaggagc tgcagccgga
    10801 agttatctgg ttacaaaaaa tcgccaaacc atcacagatg aagtcttaaa taccactgac
    10861 cgcgttcaag ctatcaaaga cgatgtggat attatccaaa atagcctgca aatcatcgac
    10921 cagcaaaaag aacttatcaa ggaataccaa gaagacttga cttacaagtt taaggtcttg
    10981 gaaaaggata tccagactag actagctgtg ataaaagaaa tgcagggaac tgaagataag
    11041 taaaaagagc ccccggctct tttttaaaac gtaaacaagt tatagtgaat tgaatttaga
    11101 atagcacacc atagtttcta aagcattgtt agagattact ttaaaatcct cttatcaatt
    11161 tgttcatatt ctatttcaat ctattatata tatcccatca actatgcatc ataatttagg
    11221 taactcatac tcaataaaaa tcaaaaagca aactagaaag ctaggcacag actgctcaaa
    11281 acaccgtttt aaggttgtgg atagaactga cgaagtcagt aaccataccc atgataagcc
    11341 gacgctgacg tggtttgaag aaatttttga agagtatcat tctccatcaa aggcatcttt
    11401 tatatggtca aagaagcctt ttttctttgg atttactttc aagtcaccag cagccgcgaa
    11461 ttctttcaag gctacttttt ggcggtcgtt caagcctgtc ggtgttacga cattaacagt
    11521 aacgtattgg tcaccaactg caccgccacg aaggctcggt gcccccttac tacgtaggcg
    11581 gaatttctta ccagtctgag ttccctctgg aataaccaat tcaacatcac cgtgaacagt
    11641 tggaatatct actgtatcac caagagccgc ttggacaaag ttgaggttga gattgtagaa
    11701 gatagtcgtt ccttcacgtt caaacttgtc gctagcttct acagaaacta ctacatacaa
    11761 gtcaccataa ggtccaccgt taaagcctgc ttcaccttga ccagcgaggc gaatttgttg
    11821 acctgtttcc acaccagcag ggattttcac atgtacgcta tgagcttgtt tctcatgacc
    11881 tgttccatga caggttgtac atggatattt gatttctttt ccttggccgt gacagacatc
    11941 acaggttact tggcgacgca tcataccaag aggagtctgc gtatcgacgt taatgacacc
    12001 agcgccatga cagcgtccac aagtgactgg acttgtccct ggcttagcac cagagccatt
    12061 acatgtacga cagccagctt cacgatgata cttaacttcc ttctcagttc cgaagatagc
    12121 ttcttcaaag gtcaaattga cacgatactg gagatcatct ccttggcgag gagcgtttgg
    12181 attgcgcgaa gaaccgcctc cgccgaagaa acttgagaaa atatcctcaa aaccaccgaa
    12241 gccacctgcc ccattgaaac cgccgaaacc accagctcca ccaaaaccac cattggcgcc
    12301 tgcagcacca tactggtcat aggcagcacg tttttggtcg tcactcaaag tctcataggc
    12361 ttcttgaact tccttgtact tgtcctcagc accaggctcc ttgttgatat ctgggtgata
    12421 ttttttggaa agcttacgat aagccttttt gatttcgtct gccgaagcgt ttttggatac
    12481 ccccagacga tcataaaatt cagtattgtt cataattcaa gatacaaagg gcgtcaaacg
    12541 gacacagcca tctaggagtt ttgacgacgg acgcttatgt cctagaaaaa actatctttt
    12601 tggcacagtc cgtagcccgt gttcagttac gaacaccctt attcctttct attgatgttc
    12661 tgaatcgaac caccatttag gtcggattca attcctttct tttatattta gtaagaaatt
    12721 ctgaaacccg tgttcagtta cgaacactct ttgttccttt ctattgatga gacaaaaccc
    12781 aaacaaatga gattccgtcc ctttttatcg aaaaacagag gctgggttgc aacctctgca
    12841 aataagtaaa ttaactttat tttgatttta aatatcctat aagtacagaa atatttatat
    12901 atttttgtct cttcttagta tttgcctata taattccaat tgatcataag aaatacaact
    12961 actgtccaaa tcataccaat tatgaacggt attacaaatt tatatgtttg tatttctaat
    13021 gatatcatag ctgataccat cgccgataca aatgcagaca acaatactga ggtaacaaaa
    13081 ttccttaccg cttcatcatt tttgatacaa ctatcatgtt cagctaatat aatttctcta
    13141 tatctagtca aacattctac tggaatatta tctataaaac cttttgctgc ttcatagttg
    13201 tcagcttgat tacaaaaatc attataaact tttcgtgtat tttttagata ctcatcatcc
    13261 aatacactca tcttactttt ccgtaaactc tccgtctacg acgtcatcgc ctgcgtttcc
    13321 tgttgcttgt gcgccttctg ctccttcttg agcttgttgc gctgctgcgg cttgttcgta
    13381 gagtttaaca gcaagtcctt gagctttttc gttcaatgct tcaagtttcg ctttcatgtc
    13441 gtccaagttg ttgtcttctt gagctttctt aaggtcatca agggcagctt gggcagcgtc
    13501 acgttctgcg tcgaagcctt taccttcagt ttccttgatt gtcttttcag tcgcaaagat
    13561 tgcttggtct acttcattac gaaggtctac ttcttcttta cgtttcttat cggcttcagc
    13621 gtttgcttct gcatctttca tcatgcggtc gatttcttcg tcagtcaaac ctgagttcga
    13681 ttggatgaca atagtttgtt ctttttgagt tccaaggtct ttggccttaa cagacacgat
    13741 accgttcttg tcgatgtcaa atgttacttc gatttgagga attccacgag gtgcagctgg
    13801 gatatcagtc aattggaagc gtccaagagt cttgttatct gctgccattg ggcgttcacc
    13861 ttgaagaacg tggatatcaa cggctggttg gttgtctgct gctgttgaga agacttgtga
    13921 tttagatgtt gggattgtag tgttgcgatc gataagtttt gtaaatactc cacccattgt
    13981 ttcgatacca agtgacaatg gcgttacatc aagaaggaca acgtccttga catcaccagt
    14041 aatcacacca ccttggatag ccgcacccat agcaactact tcatcagggt ttactgattt
    14101 gtttggttct ttaccagttt cagctttaac agcttcaaca acggcaggga tacgagttga
    14161 accaccaaca aggataactt cgtcgatttc tgacaagctc aaacctgcat ctgaaagggc
    14221 ttgacgaact ggaacttttg tacgttcaac aaggtcacga gtcaaatcat caaatttcgc
    14281 acgagtcaaa gtcatttcca agtgaagagg tccagcctca cctgcagtga taaatggcaa
    14341 gctgatttgt gttgaagtta caccagaaag gtctttcttc gctttttcag ccgcatcttt
    14401 caaacgttgc attgccatct tgtcagtaga caagtcgata ccgttttctt tcttgaattc
    14461 tgctaccaag tggtcaatga ttttttggtc aaagtcgtca ccaccaagtt tgttgtcccc
    14521 tgcagttgac aatacgtcga agacaccgtc acccaattca aggatagaga cgtcgaatgt
    14581 accaccacca aggtcaaata ccaagatttt ttcttcttta tcagtcttgt ccaaaccata
    14641 agcaagagct gctgcagttg gttcgttaac aatacgttct acttcaagac cagcaatttt
    14701 accagcgtct tttgttgctt gacgttgagc gtcgttgaag taagccggaa ctgtgataac
    14761 agctttggtt actttctcac caaggtagtc ttcagcgtag cctttcaagt attgaaggat
    14821 catagctgag atttcttgtg gagtgtattc ttttccattt gcagaaactt tttcagaagt
    14881 tcccatctta gatttgatag agataactgt atctgggttt gtgactgctt gacgttttgc
    14941 agcatcacca acgatgattt ctccgttttt gaatgagact acagatggag ttgtgcggtt
    15001 tccttctggg tttgcgatga ttttgctttc agttccttca agaactgcaa ctgctgagtt
    15061 tgttgtacct aagtcaatac cgataatttt agacatgtgt ttttctcctt gttagttaat
    15121 tttctatttt tctttttgat actcttctta agtggcgacg ccgtcagagc ttgacttcgt
    15181 caatctcttt gactaaactt tgagcctaag gtctcaaaat ttgcgcaaat agcgccacgg
    15241 cgaagagtat cgtgtttggt tcgcttcgct cactattaca aagccaaaca tattttatct
    15301 ttcttcatag tttattgtcg tttcggacaa gttttctatt atgtaaattg cgacacgaag
    15361 agtcgaaatc gattttattt cgacgacgag ttagtaagga agctaggcaa acgccatagc
    15421 gattgccgtt ttctgacgag ttgctttagc taccgtcaga attgccgaat cgaacacgcc
    15481 ctaagctctg agtaaaaaag atagattttc ttgtgttcat cgaacacttc gttaatctcc
    15541 tatttttact gcgagctttt tacgggcttt gtatcttagt tatacaccac taccattgct
    15601 gggcgtagga tgcggtcatg gagtttgtag cctttttgaa agacttgagc gatggtatct
    15661 actgggtgtt catcgtctgc tgggagagtt tgtatggcca tatggtagtt atggtcaaat
    15721 tcgccatctg ctgcgatttc ttcaattcct tcttctttca aagcgtgaat caagctttct
    15781 tgcaccatcc ccaagccctt cttcacatca tctgtcaaac cttcaactgc aagtgcacgc
    15841 tcaaggttgt caagagatgg taagattgct tttgccaagt cctggctacg ataacgttgc
    15901 aagttttgac gttcttcatt ggcacggcgt tggatatttt gcatttctgc atgagcgcga
    15961 agatatttgt tttcgaactc atctgcacgt tcatttgcca agtccaactt agacttttca
    16021 ggagttgttt cttcagctgt ttccacaact tcctcttctt gaacttcttc tacttcttct
    16081 acttcttcat tttttatatc ttgggccatg ttcgcctcct ttaatgattt caatcttaat
    16141 gtacttcgta atgattactg ctgaggtagc ggtaaaaatc tgtcaacttc atagtcaaaa
    16201 cacggttgac cacattgact tgattgatta gctgttggta atccagatta actggaccga
    16261 taatggctag aattccaact cctcgataag gaatgaggaa cttactacta atcaccgcta
    16321 ggtcagctaa acaggactct tgaccgtctg caatacgaac attttgcatc tgatcctcac
    16381 gcaacccctc acgaatctcc aaggccacct tttgcggttg gtcaaagaac tgataggctg
    16441 ctagattggc aaaattcaag agattgacct tgcccgccat cacaatgttt tcgttgaaca
    16501 tttccttaaa gatgtgttca aagagatcga tgacattatc cgttgttgta aagtaacgct
    16561 ggataatctg cggaatctcc gtccgaatct tgtagtgaat atctaaaacg gtgtgaccga
    16621 ggaaacgttc ctgaatgatg ctcttcagtt tcagcaaatc ctcctgcaag aagttccttg
    16681 gaatcagaaa ctgactagta accgttcgcg actcgtctag ggtaaatacc gccaaggctg
    16741 tatgttgccc caaaacaacg atatcaaagg ctgtcaaacg ttgcctgctc ggctcaacat
    16801 ccagtgccac taccgtacag ccactcaggt ctgttagcaa gttagcagcc tcttgcagaa
    16861 tatcctccaa tttgaagaat tcctgatcaa aggctttgac aatctcatat acctcatttt
    16921 cagccagccg gtgaaaatcc agtgagtgtt tcacatagta ctgaaaacca gcaacacttg
    16981 gcatccgacc gcttgaagta tgagccttct caagcaaccc ttgtttttct agttccgcca
    17041 tgtcattacg aatggttgca ctgctagagt taatagactc ttgcaaggct tttgatccga
    17101 caggttcgtg cgttttggta aagatgtcaa taatcagatt taaaatatcc tgctgacgct
    17161 ctgtaaccat ctcatcactc ctctctgtct gatcaattag cactcaatgc atccaagtgc
    17221 taacttatga ttctattata cacccttaga agagaatgtc aagacaaaaa ctcaaaaaat
    17281 tagcactctt ttatcaagag tgctaaaaat caatctgaag acctagaacc ttgctattca
    17341 tctactcggt atttcctttt tagtctgaaa taaccatgaa ttagataaga aatcagaaaa
    17401 gcatataaaa caaaaataag aaagaaagac atagaaagat cctctctaaa caaactcgta
    17461 caaacaacaa gaccacctaa gaaagtagtt gtacaggaac gaagtctaga tcgcataact
    17521 tcccatttga gccccttact catatagact tgatcctctg gaagtaaatc agaagacgat
    17581 ttacgaagaa tcgaacaaga acctgctcct atcaattccc aacctctatc tctaaaatct
    17641 tgcagttcat gcttatattt tttaagaaat ctagaatcat agatacggta gatgacatcg
    17701 tctggttgac attggtcaaa atagaacaaa ccaaaacgac tcgttctata cctccaacct
    17761 ttcaaatgca tctcatgtaa atattcttct tccttgtcca aatcaacaat agtgaaaatc
    17821 cgaaattcta ctctgctatt cattgtctta ccccaaaatt agaaaacatg cctggcgtta
    17881 tttattagat aattctttcc gcttttgact caatctccaa aaaatataag aaatctgaat
    17941 cgcaaaaact atcaataaaa cccaatctat tatgaaagtc aaaaacactt cccaactgaa
    18001 agaactacct ccagtgacaa actttgagaa aaacggtagt agagctaaaa agagaagcaa
    18061 aataggaagc atccgcattg ttaaaatcct tttggcataa aaaaatcttt atttaaacga
    18121 aaatattatg gcaaaattta cgccagtttt tgaacggctg atgtagatat tttatacttt
    18181 caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc gactgaaagt
    18241 gcttataaat gataataagt cgcctgccga aaacagcgaa aaatagcggt gttatgcgga
    18301 gataatctga cgcgatgcga aagtatattg catacttatt ttcaacaatt tagcagagta
    18361 tttttataag tgtgatataa tagaagtata atttgttctg atagtttatt ttatggagaa
    18421 gtagattttt agaatgcgga gggttcaata tggttgagtt tataaagtct aagaaagaaa
    18481 tgagtgagga ggatattaaa gcaaatttca tcactcctgc tattgtatcc aaaggatgga
    18541 aaaatggtga gcatatcgct tacgaagaat acttcactga tggtcgaatt gaggttagag
    18601 gagataaggc tcgtcgtaaa gaaggaaaaa aatcagacta ttcactgtat taccaatttg
    18661 gaactcgaat tgcaattgtt gaggcaaagg ataataaaca cagcgttcga gcaggattac
    18721 aacaagctat tgaatatgga gagattttag atgttccatt tgtttattct tcgaatggtg
    18781 atggctttat tgaacacgac cgtatcacga gagaagaacg tgagctggag ttagatgaat
    18841 tccctactcg tgaagaatta ttttctcgta tgacgaagga aaaaggattg acgtacgaaa
    18901 ttacagaagc tatctcaact ccatactata cagacgcctt ctcaatgaaa acgccacgct
    18961 attatcagca aatagctatc aaccgtacta ttgaaacagt tgccagagga caaaaacgag
    19021 taatgtttgt gatggcaaca ggaacgggga aaacgttcat ggcttttcaa attattcatc
    19081 gccttcgaaa agctggtttg gctaaacgag ttttattctt agcggataga aacatcttag
    19141 tagaccaaac gatggctgaa gactttaggc cattcgaaaa ggtaatgacg aaaattacac
    19201 caaaactttt gactgctcct gaaaaattaa attcttttga aatttatcta gggctttatc
    19261 agcaactaac tggtgaagat ggaactgaaa cacattatca aaaatttgac aaagacttct
    19321 ttgatttaat cgtaattgat gaagcgcacc gtggttcagc taaggaaaac agtaactggc
    19381 gtaagataat tgattatttc agttctgcga cacagattgg gatgaccgct actcctaaag
    19441 aaaccaagaa tgcttccaat acggaatact ttggtgagcc aatctatact tatagtttaa
    19501 aacagggaat cgaggatggt tttttggctc catatcgtgt tatgagagtt aatttagatg
    19561 tagatgtgga tggttatcgt ccagaaactg gaaaagttga tgctaacgga caattaatag
    19621 aagataggta ctacggcagg aaagattttg ataaaaccat tgtcattgat gatagaacgc
    19681 aaagagttgc caagtttgtt tctgattata tgaagcaaaa caatgcacga tttgataaaa
    19741 caattgtttt ttgtgttgat attgaccatg ccgagcgaat gcgtgctgca cttgtaaaag
    19801 agaatctaga cttagtccaa gaagactatc gttatgtcat gcaagtaact ggtgacaacg
    19861 ctgaaggaaa agctcaactg gataacttta tggatgtcaa ttctaatttt cccgctattg
    19921 taacaacgtc taaattatta acgacaggag ttaatgctaa aacatgtcgt ttgattgttt
    19981 tagactctaa tatccaatcc atgactgaat ttaaacaaat tattggtcgt ggcacacgtc
    20041 tttatcctca aaaggggaaa gaatttttta cgattattga ttttcgaaat gttaccaatt
    20101 tgtttgctga ccctgatttt gatggtgatc cagtgaaggt gctggaaaca ggtgcgaaaa
    20161 cagtcagtgg ttctacgccc ggtttcgtaa gtgaggaagg tgacccagta gaaaaatata
    20221 tcgttacaga caagcaggtt accattctta attctactgt tcaagtattg gatgaaaacg
    20281 ggaaactgat taccgaaagc ctgaccgact acactcggaa gaatatctta ggtagctacg
    20341 ccactttgaa cgattttatc acagtttggc atacggcgga taaaaagaag cttatcttag
    20401 acgaacttta taaaaaagga gtttatctag atgctattcg agagtcggag ggaatatcag
    20461 aacaagaaat cgatgatttt gatttactcc taaaacttgc ctatggtcaa aaagaattaa
    20521 ccaaaacgga acgtatcaat aagctcaaac aaagcggata tttatataaa tatagtgagg
    20581 aagcgcgtgc tgttttggaa attttactga acaaatacat ggataaaggt attggagaac
    20641 tcgaaagcat tgaaacatta aaacttccag aatttcagat atatggtgga accttcaaaa
    20701 tcatcaatac ttattttgga gataaaaaac gatatttaca agcaattaaa gaattggagc
    20761 aagagctatt tacagtagct taatgaaagg aaagtatgtc aattacatca tttgtaaaaa
    20821 gaattcaaga tatcactcga aacgatgctg gtgttaatgg tgatgctcaa cgtattgagc
    20881 aaatgtcttg gttattattc ttaaaaattt atgatagccg tgaaatggtt tgggaattag
    20941 aagaagacga gtatgagtca attatcccag aggaattaaa atggcgaaat tgggctcatg
    21001 ctcaaaatgg ggaacgggta ttgacaggcg atgaattact tgattttgtc aataacaagt
    21061 tattcaaaga gttgaaagag cttgaaataa cttcaaatat gcctattcga aaaacgattg
    21121 ttaaatcagc ttttgaagat gcgaacaact atatgaaaaa tggcgtcttg ttacgccaag
    21181 tcatcaatgt tattgatgaa gttgatttca atagccctga agatcgtcat tcgtttaatg
    21241 atatttacga aaaaattctt aaagatattc aaaatgctgg gaactcagga gaattttata
    21301 cgccacgtgc agcgactgat tttattgccg aagttcttga cccaaaactt ggagaatcaa
    21361 tggcagacct tgcttgcgga acaggaggct tcttgacttc gactctgaac cgtttaagta
    21421 gtcaacgtaa aactagtgaa gataccaaaa aatataatac agctgttttt ggtattgaaa
    21481 agaaagcatt tcctcatctt ttagcagtta caaatctgtt tcttcacgaa attgatgacc
    21541 ctaaaattgt tcatggaaat actttggaga aaaatgttcg tgaatatacg gatgatgaaa
    21601 aatttgacat tattatgatg aatccacctt ttggagggtc agaattagaa acaataaaaa
    21661 ataactttcc agcagaatta cggagttctg aaacagctga tttatttatg gctgtcatta
    21721 tgtatcgttt gaaagaaaat ggtcgtgttg gagttatttt acctgatggt tttctatttg
    21781 gtgaaggtgt aaaaactcgc ttgaaacaaa aactggtaga tgagttcaac ttacatacga
    21841 ttattaggtt gcctcatagt gtctttgcac cgtatacagg aatccatacg aacattcttt
    21901 tctttgataa aacaaagaaa acagaagaaa cttggtttta tcgtttagat atgccagatg
    21961 gttataaaaa tttctcgaaa actaagccga tgaagtcaga acacttcaat cctgttcgtg
    22021 actggtggga aaatcgtgaa gagattttgg aaggtaagtt ctacaaatct aaatcattta
    22081 cacctagtga attggctgag ttgaattata atttagacca gtgtggcttt ccaaaagagg
    22141 aagaggaaat cttaaatccc tttgagttga ttcagaatta tcaagcggaa agagcaactt
    22201 taaatcataa gattgataat gtattagctg atattttgca gttgttggag gacaaataat
    22261 gacaccagaa caacttaaag caagtattct ccaaagagcg atggaaggga aattagtgcc
    22321 gcaaaatccc aatgacgaac ctgcaagtga attattaaag agaattaaag ctgaaaaaga
    22381 aaaacttatc agtgaaggaa aaatcaaacg agataaaaag gaaactgaga tatttcgtgg
    22441 tgatgatggg aaacattatg ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc
    22501 ttatgatatt cctgatactt gggagtgggt gaggttttct acattggttg aaattgtcag
    22561 aggtggctct ccacgaccaa tcaaagatta tcttacttct gaagtagatg gaataaattg
    22621 gataaaaata ggtgatactg aaaagggtga aaagtatata aataatgtta aagaaaaaat
    22681 caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa ggtacatttt tgttaactaa
    22741 ttctatgagt tttggtagac cttatatttt gaatgttgat ggtgcaatac acgatggatg
    22801 gttggctatt tcgaactatg aaaactcatt aaataaagat tacctattct atattctttc
    22861 atcaaatgta gtttattctc aatttctatc tctaattagt ggagctgttg tgaaaaactt
    22921 gaatagtgat aaagttgctt ctattcttat ccctctcccc ccactatccg aacaacaacg
    22981 cataatagaa gcaatcgaat cagctttaga aaaagtagat gaatatgctg aaagttataa
    23041 tagactagaa cagctagata aagaatttcc agataaacta aaaaaatcta ttcttcaata
    23101 tgctatgcaa ggaaaattag ttgaacaaga cccaaatgat gaatcagtcg aagttttact
    23161 tgaaaaaata cgagcagaaa aacaaaaact ctttgaagaa ggcaagatta aaaagaaaga
    23221 tttggacatt tctattgttt cccaaggaga tgataactct tattatgagg aagtaccttg
    23281 tgaaatacca gaaagttggg aatgggtgag gttaaacgat ataacctcct acattcaaag
    23341 agggaagtct ccaaaatatt caaatattcc tatataccct gtgattgctc agaaatgtaa
    23401 tcaatggtct ggcttttcta ttgacttagc aagatttatt gatcccgaaa cagttcatag
    23461 ttaccagaaa gaaagattac taagagatgg tgatttaatg tggaattcaa caggtctagg
    23521 tacgttagga cgattagcta tttaccatga aaataaaaat ccttatggct gggctgttgc
    23581 agatagccat gttacagtta taagagtctt atcgggagtt attaattgcc atttcatcta
    23641 taattttctt tcctctccta ttgttcagtc agttattgaa gaaaaagcgt cgggtagtac
    23701 aaaacaaaaa gaattattaa cgaaaactat aaaagaatat ttaatccccc tcccacccct
    23761 tcctgaacaa tccagaatcg ttgataaaat cgaacaattt ttcgcccata ttgacgcact
    23821 aatttagtat aatagtttta cgtgcggtgg aatttctatc aaacataaga taggagtttt
    23881 acgttgaaag attttgaatt acatttgaag aaagctggtt tagctgaaaa tactgtgcgt
    23941 tcgtaccttt atggtgttcg atttttcttg gagaattacg aactcaaaat ggaagattta
    24001 tttgaataca aaggatattt attagacaat tttaaaccta aaactgtcaa tttgcgacta
    24061 caaggagtaa ataaatatct ggcttttatt ggtcatgatg atttgaaatt aaaatttgtc
    24121 aaagtacagc aaaaaccgtt tttagaagat gtcattagcc atgctgatta cctttttctt
    24181 aaacgtagtt tgaaaaaaga tggtatttta aaatggcatt ttgtcgtttg gtttttaggt
    24241 gcaactgggg ctcgtgtaag tgaacttatt aaactaaaag tagagcatgt agaaatcggt
    24301 tattttgaca tttactcaaa aggtggtaaa attcgtagac tgtacattcc taaaaaatta
    24361 agaaatagtt gtcttagttg gttagaatca gaaaatcgcc gaagtggtta tttatttttg
    24421 aataaattta acgaaccaat tacagcaaga ggagttgctc aacagttaaa aaattatgct
    24481 gataaataca aaatgaatcc taaagtaatt taccctcatt cttttaggca tttatttgct
    24541 aagaattttt tagcgaagta taatgatatt gccttgcttg cagatttgat gggacacgaa
    24601 agtatagaaa ctactcgaat ttatctaagg aaaacagcta ctgaacaaca aaatattgta
    24661 gataaaattg ttaattggta aaaaataaca ggtggtcaaa ctgactacct gctatttttg
    24721 tgattatggc tcttattatg ggaataaaga cgaaacaacc tcttatccta tatatgaaat
    24781 cccagaagca tggagatata ttaaatttgc tagcctagtt aacttcagaa taggaaaaac
    24841 tcctccacgc agtgaagcta ctttttgggg aactgaaata ccttgggtat ctatatcaga
    24901 tatgcctata tctggttatg taactaatac gagagaatct atttctaaat tagcattaaa
    24961 atcaaagaaa atagacattt cacctaaagg aactttatta atgagtttta aattatctat
    25021 tggaaaagtt gccatattgg atattcctgc cactcataat gaagccatta tatcgatatt
    25081 cccctatgct aataaagaaa atattatcag agattactta atgatatttt tgccacttat
    25141 ctctacttta ggtgattcaa aagatgctat caaagggaaa acattaaata gtaccagtat
    25201 ctccgaatta ttaatcccta tttctaatca tgaagagatg aaaagaatca tttccaaagt
    25261 tgatttactt tttcaaaaag tttctcaact ttttgagtaa taagttcctg ttcctcaaaa
    25321 ggagctaacg gaattaatag ctcgctcagt gtagttttag gaatattata taaagcttga
    25381 cctgatagtt tagttattgc tttcaattgt ttataaaata acggagaaga caagttaaat
    25441 aatagaaatt ttgaaataat ctctgaactt tcgaatggtg ttaattggaa aataaatcca
    25501 ccagccacaa caccatcata gtctttatcg attcttgcaa actttccaat atgttctaaa
    25561 gaggttgata caggtgttat tagctgatta tgttttaaat aaacttgttc agaggagatg
    25621 aattgtgtat caatgtagta atcgttatcc aacagagaaa attctaaagg cttaatatta
    25681 ccaccacgta taattctaac acctttatta ttaatgctta aatcgccctt cttgtaagaa
    25741 agacctgtat tcattgaaaa aatatctttt atttttataa caacccaatt cataggt
//
LOCUS       DAVMBH010000028        24895 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVMBH010000028 DAVMBH010000000
VERSION     DAVMBH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24895
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.028"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(295..1194)
                     /gene="galU"
                     /locus_tag="VYP30_001310"
     CDS             complement(295..1194)
                     /gene="galU"
                     /locus_tag="VYP30_001310"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1808302.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(1216..2232)
                     /locus_tag="VYP30_001311"
     CDS             complement(1216..2232)
                     /locus_tag="VYP30_001311"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1808303.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVGAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            2444..2824
                     /locus_tag="VYP30_001312"
     CDS             2444..2824
                     /locus_tag="VYP30_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1808304.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(2998..3423)
                     /locus_tag="VYP30_001313"
     CDS             complement(2998..3423)
                     /locus_tag="VYP30_001313"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808305.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(3499..4149)
                     /gene="phoU"
                     /locus_tag="VYP30_001314"
     CDS             complement(3499..4149)
                     /gene="phoU"
                     /locus_tag="VYP30_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1808306.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(4164..4916)
                     /gene="pstB"
                     /locus_tag="VYP30_001315"
     CDS             complement(4164..4916)
                     /gene="pstB"
                     /locus_tag="VYP30_001315"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1808307.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(4918..5733)
                     /gene="pstA"
                     /locus_tag="VYP30_001316"
     CDS             complement(4918..5733)
                     /gene="pstA"
                     /locus_tag="VYP30_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1808308.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(5726..6589)
                     /gene="pstC"
                     /locus_tag="VYP30_001317"
     CDS             complement(5726..6589)
                     /gene="pstC"
                     /locus_tag="VYP30_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1808309.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(6707..7582)
                     /locus_tag="VYP30_001318"
     CDS             complement(6707..7582)
                     /locus_tag="VYP30_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1808310.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIESKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(7749..9080)
                     /locus_tag="VYP30_001319"
     CDS             complement(7749..9080)
                     /locus_tag="VYP30_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1808311.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(9081..9788)
                     /locus_tag="VYP30_001320"
     CDS             complement(9081..9788)
                     /locus_tag="VYP30_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808312.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(9872..10174)
                     /locus_tag="VYP30_001321"
     CDS             complement(9872..10174)
                     /locus_tag="VYP30_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1808313.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYETVTLGLNISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(10161..10382)
                     /locus_tag="VYP30_001322"
     CDS             complement(10161..10382)
                     /locus_tag="VYP30_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1808314.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYVRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            10344..10902
                     /locus_tag="VYP30_001323"
                     /pseudo
     CDS             10344..10902
                     /locus_tag="VYP30_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11217..12908)
                     /locus_tag="VYP30_001324"
     CDS             complement(11217..12908)
                     /locus_tag="VYP30_001324"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1808315.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NEDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            13044..13490
                     /gene="argR"
                     /locus_tag="VYP30_001325"
     CDS             13044..13490
                     /gene="argR"
                     /locus_tag="VYP30_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1808316.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            13541..16075
                     /gene="mutS"
                     /locus_tag="VYP30_001326"
     CDS             13541..16075
                     /gene="mutS"
                     /locus_tag="VYP30_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1808317.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            16222..17916
                     /gene="patA"
                     /locus_tag="VYP30_001327"
     CDS             16222..17916
                     /gene="patA"
                     /locus_tag="VYP30_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1808318.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(18246..18509)
                     /locus_tag="VYP30_001328"
                     /pseudo
     CDS             complement(18246..18509)
                     /locus_tag="VYP30_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            18703..20469
                     /gene="patB"
                     /locus_tag="VYP30_001329"
     CDS             18703..20469
                     /gene="patB"
                     /locus_tag="VYP30_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1808319.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSAGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            20608..21297
                     /locus_tag="VYP30_001330"
     CDS             20608..21297
                     /locus_tag="VYP30_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1808320.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            21301..21480
                     /locus_tag="VYP30_001331"
     CDS             21301..21480
                     /locus_tag="VYP30_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808321.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            21467..22816
                     /locus_tag="VYP30_001332"
     CDS             21467..22816
                     /locus_tag="VYP30_001332"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1808322.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            22940..24400
                     /locus_tag="VYP30_001333"
     CDS             22940..24400
                     /locus_tag="VYP30_001333"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1808323.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            24414..24848
                     /locus_tag="VYP30_001334"
     CDS             24414..24848
                     /locus_tag="VYP30_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1808324.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         7404 a         4885 c         5316 g         7290 t
ORIGIN      
        1 tttaatttaa ccatgactac tccaacagtt aagtcaaatt taaaattatt tattattttg
       61 gaaccattag aaacaacaca gcaaagttaa aataaggctt tgtccgtaca caacttgaaa
      121 aagtgcgcac cgattcggtg cttttttgtt ttactatact aatttattct actcttattt
      181 taatgaaaaa acaaatacaa gtatagcgtt ttcattagtt tttattaaat aggtagattc
      241 aagtagagaa tttacttaat ttatgtgtgg ctaatcttta tataaatgat tttgttattc
      301 cttctcagtc aattcttttc caagttggat gaggtaattc ttcaaatcat ctttgacttg
      361 tgggtgtttg agggcgtagt cgatggatgt tttcatgaag ccaaacttgt ctccaacgtc
      421 gtaacgagct cctgtaaatt cacgggcaaa aacacgctgt gttttattaa gagtatcgat
      481 tgcatcagta agttggattt catttccagc accaggagct tgcttttcga gaatctcaaa
      541 aatttcaggc gtgaggaggt agcgtccgat aatagcaagg tcgctaggag cgtcctctgg
      601 agctggtttt tcaacaaagg tttcaacact gtaaagacca tcttttcctt cgccttgcgg
      661 agcaataacc ccgtaagcag atacttcgtc atgagggact ggcatgacag cgatagtaga
      721 cgcgtgggta cgctcgtagt catccatgag ttgtttggta agtggaacag ccttttcgtc
      781 tgtgatatcc atcaagtcat caccaagcat aacgacaaaa ggttcatttc cgacgaaagc
      841 cttggcttgc aaaacagcat ctccgagacc gcgtggatga gtttggcgga taaaatgcag
      901 acgcatgcca gttgtttcat caactagctt caaaagatct gttttccctt tttctttgag
      961 gttatattcc aattcgaagt ttgaatcgaa gtggtcctca atagaacgtt ttgatttacc
     1021 agtgacaact agaatatctt caatacctga tttgagagct tcttccacga taaactggat
     1081 agttggtttg tctacgattg gcaacatttc tttggcaagg gccttggttg ctggtaaaaa
     1141 tcgagttcct agtccagcag cagggataac tgcctttcta acttttgatg tcataaaaat
     1201 cctttctata gagggttaag accactcatt ttctgcttta aattcattgt tcatgatgtc
     1261 ataaatggca tctttgatat tggttccgtg ataaataact tggtaaatag cctgtgtaat
     1321 gggcatatag actccaagtt cttgggctag ttcataggct gctcgagtcg ttgaaattcc
     1381 ttcgattacc atgcccatat tagcttctat atcagctagg gattctcctc gtccgagagc
     1441 atctccagct ctccagttac gagagtggat ggaagttccc gttacgatca aatctcccac
     1501 accagataag ccgctatagg tcaatggact ggccccgagt gctaccccta ggcgggtgat
     1561 ttctgctaaa cctcgagcga tgatggctgc cttagcatta tcaccaaatc caagaccatg
     1621 taaagctcca gcaccgacag caataatatt tttaagagca ccagcagttt caaccccgat
     1681 aacatccgta ttggtataaa gtcggaagta gtgattacta aatagcttct gaacgtattg
     1741 agctgtttgt aaatctttag aagcagcagt tattaaagtt aggtcacgca caatggtctc
     1801 ttctgcatga ctaggccctg aaacaacgac gatatcacta cggagatgtt caggaatttc
     1861 ttcttcaaga atggttgata atcgtttatg gctatcaggt tctaatccct ttgatgcgtg
     1921 catgatgata accttatggt ccaaggtttg tgcaacttgc tgggcaacaa gtcgtgtcac
     1981 ttttgttggg acaacaaaca aaatcgcacc cacatttttc aatgtttctg ctaagtcggt
     2041 gtaggcaatg atattttcgt ctagaacgac atctttaaag tagtgcttat tagtatggtg
     2101 tgtattaatt tcattgattt gctcgggaag atttccccaa atacgtacct cgtgtccatt
     2161 gtcatttaag acttgtgaaa gggcggttcc ccaagaacca ggccccaaga cggcgacggt
     2221 ttgtttttcc atgatttcct ccttgataga gttctttctc ttattctatc atattctagg
     2281 ggattttgca cttgcattac tggggtatgg tggaaaaata cacaaaaacc gagacgaagg
     2341 gataaactct tagtctttag ttaaagtgag aagaaatctg atagatagtt tgattcagta
     2401 tatgcttata atagaggtaa acaactcagg aggttcttgt aggttgcgag agtttggcga
     2461 aaaaattaaa agattacgtt tggctaaaaa aatcagtcgt tcagaatttt gtggtgatga
     2521 gtctgaatta agtatccgtc aattaattag aattgaaaat ggagaatcca gaccaacact
     2581 aacaaagtta aaatatatcg ctgaacgttt gggggttgaa gattacaagt tgatgccaag
     2641 ttatatagag ttggataagg aatacctaga attgaagtat ttcttgatga gaactcctac
     2701 atacgaagat gaaactatcg cccaaaagaa agagagtgtt ttgataagat ttttgaagag
     2761 tattatgata ggctacctga ggaagaaaga tttatcatcc caaattattc atatctggca
     2821 ctaacgaact acacagttca aaaattacca gaaaagctag ttgaaatact gtccttctgg
     2881 tgattttgct taatttctga tgttcgagac ataattgagg agatttgtct tgattttttc
     2941 ctaaaaaagg gtagactcct cccttggttt gatgctcgat ttttaaaata aggtgactta
     3001 ttctgttagg catgttttcc cctgccctct agctctatat ggaacaggga gtatcagatt
     3061 tatctggcag attgtatcaa ataaggcttg aaactgtttt gaataggcgt atagacttga
     3121 gaatttgaga atatgtcgtc tagcagtaga gacatatttt ccggcaatat gaaggaagag
     3181 acgtcgaaaa cgcttgatag tcaaggcctt tacttcatca ccagctagct gctttaaaaa
     3241 gaggtagaga ttataagcca gacagcccat catcatacgt acttcattct taatcatggt
     3301 cgaactatct gtcttatccc caaagaatcc tgctttcctt tctttgataa agttttcagc
     3361 attccctcgt tcacgataga attgaaacag ctcctcacta tctacactgc ttaaattggt
     3421 caaatgaact tttttacaac cataaaaaag agcacttaat cgtactcttc tcttttaagg
     3481 attaaaggat tagttgaatt aattcaaatc cactagttct cctgtttcta ggtagactag
     3541 gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc agatgcccta tgatataaag
     3601 gtattgtgtt ccattgggaa ttgaggtttc ttggtctttc ataagtccaa tgatttcctt
     3661 tgataaggca taataatatt ggtcaatctg ttcatctttt tgagcaatac taatagcttt
     3721 tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggct agcatgctga gggataattt
     3781 acccatttgg tgtaactgtt cttcgtcagg ggctagttga ttttctttta gttgcaaaac
     3841 agctttggca atgcctgcca tatggtctcc catacgttca aggtctgaac aagaagacat
     3901 gatgctaatc acaaatcgaa ggtcagacac ttgtggctgc tgcaaggcca acaaacgggc
     3961 acaggtcaat tcgatagcgc tttgaccttg gttgatagca tgatccttat tgataattag
     4021 ctctgccatc tccttgtctt tggaggctaa ggccagtaag gcttttgaag ctgtttcaag
     4081 gacaagttgc cctagtccta aaaaggattg ttctaattca tgcaattcta agtcaaattg
     4141 atttctcata ggtttttcct tccttatccg aaccgtcctg aaatatagtc ttctgtgcgc
     4201 tgatcttttg gattggtaaa cacgtcaacg gtatctccaa attcgcaaat ttctcctgtt
     4261 aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt gcatgttatg ggtaacaatg
     4321 ataatcgtat aatccttttt tagttgctga atgaggtctt caatttttaa agtggagata
     4381 gggtctaagg ctgaagtcgg ctcatccatt aacagaatat caggttctac tgctaaagct
     4441 cgcgcaatgc aaaggcgttg ctgctgaccg ccagataagg acatggcact ctttttaaga
     4501 tcatctttga cttcttccca aatggctgcc ccttttaaag atttctccac taaggcatct
     4561 aattgttttt tgtctcgaat accatgtgtc cttgggccat aagccacgtt atcatagata
     4621 gacatggcaa agggattagg ctgttgaaaa accatcccta cacgcttacg tagctgatta
     4681 aggttgaatt tgctactata aatatcttgc tcatctaaga ggacttggcc ttcaatatgg
     4741 caagaaggaa ccaaatcgtt catccggtta agggttttta gaaaagttga tttgccacaa
     4801 ccagatgggc ctatcaaggc agtaatctgt ctttctggta attgaatcga aatatttttt
     4861 aaggcttgaa aatccccgta aaataagtct aggtgtctga ctgaaaatgt tcccatacta
     4921 ggaagctcct ttcacaagtt ttcgagataa taagcttgat agagtattta tcattaaaac
     4981 agtaataatc aaaatcacgc cggtagcata ggcttcattg acatgtagcc cctcacttga
     5041 cagcatatac atatgtaggg ctagagaacg gcctgaagac atgagactac ttggcgtatt
     5101 ggtagaggta cctaatgtat acatgagggc agctgtttca ccaacgatac ggccaatagc
     5161 tagtatcact ccagctaaaa tacctggcat ggcaactggt agaacaattc taaaaacagt
     5221 ccgtaactta cctgccccaa gtccataact tgcttgacgc atgctatcac taacagataa
     5281 aagggcttct tctgttgagc gaataatgac tggcaacacc atgataactg aggttaagat
     5341 tcctgataac agagagtatt gaaaacctaa gaagactaca aagaagagca tgccaaacag
     5401 accaaaaaca atggaaggaa tcccagataa ggtatctgag gccaatcgca tgattttaac
     5461 acaaagggaa tctttttttg tatattccac aagataaaaa ccagcaaaaa tccctatggg
     5521 caaggctaaa agaagagcac caaagaccag aataacggtg gaaataatcg ctggcataag
     5581 ggaaatgttc tcagaagtat aagtccaaga aaagagggat agacttagat gaggtaagcc
     5641 tttgatgagg ataaaaccaa tgattaaaaa gagagagcca aaggttaaag ctgaaaaaca
     5701 ataaacgaga agttttagca ggtatttact cataagatga ttttcctttc aagtaggcaa
     5761 agtaggcatt aatcaagaga ataaggaaaa agagaactgc tgaggttgca ataagggctt
     5821 ccctatgctg acctgatgcg taagccattt ccagaacaat attggttgtt aaggttctgg
     5881 ttcctgaaaa gagtccactt ggaataatcg gctggttgcc tgccaccaaa ataactgcca
     5941 tggtttcacc tactgcgcga ccaattccta aaataactgc tgataaaata ccagatctcg
     6001 cagctggcaa gatgacacta aaaatactcc gttcatgact agctcctaga gccaagctac
     6061 cagaataata cgttttggga actgttcgga tagcagattc tgacaaactg ataatggttg
     6121 gcaaaatcat tattcctaat agtaacgaag cggttaggac actcatgcca tttcctaaaa
     6181 aggttctaat ccaaggcacc aataattgta ggccgaaaaa accataaaca atagatggaa
     6241 tggccgccat caagttgata gctgatttta agaagccata gacgggcttt ggacaataat
     6301 aaaccataaa caccgatgtc aagatgcctg ttggcacccc aatcacaatc gctcctaagg
     6361 taattaataa ggaaccaacg atcattggta aaataccata gcttgccgga atgttcgttg
     6421 gcgaccaatc actgcctaat aaaaaacggg caaagccgta gttagccatg aaaggtaagc
     6481 cattactaaa aataaagaaa cagattagca aaatagctac aacagctact gttgcactca
     6541 tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg ttttgtcaca tcttgtcctt
     6601 tctagtgaag aaagtaaggg agatacgaca cctccctact tgccttcttt atcttattgt
     6661 acgatgaaac gtctgcatct ctttagagat ttatggagca aacattttat ttaatcttgt
     6721 cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc agccatactg acttggcttg
     6781 ccttattgtc attattgacc acaacagcaa taccgtctaa agcaatagca tcatgggtga
     6841 gactcttacc ttcttcagga gttagttccc tagaaaccat accaatatca gcggttttct
     6901 ccttaacagc ggtaatacct gctgaagacc cattagaggt aatatcaatc gtaacttctg
     6961 gattttcttt tttataagct tctgctaatt tttccattaa agaagatact gaagtggaac
     7021 ctacaacaga caacttgcct gataagtgtt ggcttgtata ttctgtggtt tcggttttag
     7081 attcaataaa tttattatct gtgaccactt gttgaccttg tttggagtgg ataaagctga
     7141 taaaatcttg acctagcttg gaaagattag aagaccaaac aatgttgaag ggacgttgaa
     7201 gagggtattc accatctaaa actgtgtctc gactagcctt gacaccatca atctctaaag
     7261 ccttgacaga tttcgttaaa gatcccaagg agatgtagcc gatagcatta gcattccctt
     7321 gaactgctga gagaacacct tctgtactat tttgaatcac agctgttttg gcagtgttgt
     7381 caattttttt atcaccgtct tttttgagaa tccctgtgat ttctgtgaag gcaccccgtg
     7441 ttccagagcc attttctcgt gaaatcacct caatcgttcc tgaagctgac tgtttggaag
     7501 cagctgactg attgccacag gcaacaagcc caaatcctga taagccaatg gctgcaagag
     7561 taagcatttt tttgaatttc ataataatca cctttatctc tatgtatttt tcttgtgtag
     7621 gcttactaca tttatagtct aacaagtctt tgtaaaggtt tatccctgat tcatgtaaag
     7681 attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg ctgctcctaa aaatagcttt
     7741 aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa aaatcgtgaa gcaactgcct
     7801 ctgccaagct gactcgtcac cgtgacttgg ccacctaata attgactgag ttctttgaca
     7861 atggcaaggc caagaccagt gccaccagtt tgtctgcttc gacctttatt aactcggtaa
     7921 aaacgttcaa aaatacgatc ctgctctaat tgactaatac caatccctgt atctgataca
     7981 gaaatcttaa tgccttcgtt caccttttgg gtcttgacct caattttccc cccttgttca
     8041 gtgtaacgga tggcattgga taaaagattg agtaagattt gggaaagtaa ttgactatct
     8101 gatacgaggg tgacatcatc tggcacctgc acctttagct gtaaatcctt cttcttgagc
     8161 tgaggttgca agctttgagt caaatcctgt acaaattctg ccaaagaaag ggtcgtccat
     8221 tgtataggca tttgttgagc cttagataag gtaagaagat gctcaacaat atgctcaaga
     8281 cgcaaacttt ctttgtaaat aatgtctaga aagtcatcct tgagcgcttc ttcttcagct
     8341 gacatcccct taatggtttc agcaaagccc ttaatcgaag taactggtgt cctcaattca
     8401 tgggaggcat ttgagacaaa ggctaaattt aacttttcat aagttctaat cgttgttaaa
     8461 tcatatagca agacgagcac agcttccaca gattgggtgg ggctaaaaac gggaactgct
     8521 gtcacttcta aaatcaagtc accctcatga aacccactta cttcttgttt taaccttgtt
     8581 ttttgatcaa aggcttggtg aactaaattc cgaatatcca tccgtttgag gtcatcaagt
     8641 gaacttatgt cgccgtccac atcgggaaaa taatgaggca gagagcgact ggataataac
     8701 atctgacctt gagcggaaac taaaaacgtc cccatggtta ggtgcgacag aagaacctcc
     8761 attgtttcgg ctaggtcctt gtattgctga tcctgttggg agactttggt ttttagggca
     8821 gacacatact gagccaaaga ctttaagtct tcttgccctt tttctaaaaa gtattcacta
     8881 ctggtcaaga gaggttggtg caaggtctca aaagcaactt cccatttcca aaggcaaaag
     8941 agccagtagc caccttgtcc caaagaaagg gctagaagaa agagaccgat gcctttactg
     9001 atccaagtta atgccatccc tgcaatcaga atgaggctaa cacttagatt gactagccaa
     9061 aattgaaggt agcgtttcat ctataactcc ttgaacttat aaccataacc ccgaatggtt
     9121 cgaataaatt gaggggcttt aggattgtct tcaatttttt ccctcaactt accaatatga
     9181 acgtccacca aacgtgtttc ctgcccaaag tcataccccc agatacgttc caaaagacgc
     9241 tctctagtca gtgtcatgtt gggatgtttc ataagataga gcaagagttc aaattctttt
     9301 ggggtcaaac tcagtaactt attcgccttg tagacttcat gacgctcagg gtatactttc
     9361 aaggtcccaa atagccaaga atcgtcagcg atattatctg aatcatctcc ttcttgttct
     9421 cctttagttc gcctgaggac agccttgaca cgcgccagca attctctagg gctaaaaggc
     9481 ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa ccttatcaaa ttcatcactt
     9541 ttcgcagaaa ccatcataat tggagttttg acgcctttgg ctctcagccg cttacaaact
     9601 tccatgccat ctaattgtgg taacatgata tcaagcaaga taaaatcaaa gggttctgtt
     9661 tctgccaaag ctaaggcctt ccgtccattt gttaccaatt gagtagaaaa gccttcctta
     9721 cttaaatggt agtcaagcaa tttcagaatg tgttcttcat catccactaa taagacttgt
     9781 tttgtcatct attatctcct attggtaaca ttataacaca attatcagaa atcctaacat
     9841 tgctaaatca gattaaattt gcttatcaag actagtatct ggtcaaacgc tcaatcatct
     9901 ccttgtgctc tggataggtc gccagtagat ctaccctttc aaataattca aaatcctcaa
     9961 attcaaaacc aggagcaaca agacaagaaa ccagagcatc atccttatca actgttgatc
    10021 cccaaatagt gcccttagga acacagtagt gaagttgttg ccctttggat atgttcaggc
    10081 ctaaagtgac tgtttcgtag tgaccatctg ctgtaatcat gtgaacagta agtggggatc
    10141 ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg aaaatgtgaa ggattcgttt
    10201 cttcttaata agaaataaat actggtataa agcgcccttc ccttaccagc aaggtttata
    10261 gtgtctgaag ctttttttgt ttgtctaaca tagccacctt caacatgggg agctaactct
    10321 agagttctta tcaagtcttc tttatccgtc ggagccaatg ggttgaagta actcttgttc
    10381 aaagtggtgt tacgatttca agaactcctc tcagctctga ggacacggta atgattgatg
    10441 cgacggaagt acaaatcaat cgccctaaaa aaagaattag cgaatgattc tggtaaaaag
    10501 aaatgccacg ctatgaaggc tcaagcgatt gtcacaagtc aagggagaat tgtttctttg
    10561 gatatcactg tgaactattg tcatgatatg aagttgttca aaatgagtcg cagaaatatc
    10621 ggacaagctg gtaaaatctt ggctgacagt ggttatcaag ggcccatgaa gatatatcct
    10681 caagcacaaa ctccacgtaa atccagcaaa ctcaagccgc taacagttga agataaagcc
    10741 tgtaaccatg cgctatccaa ggagagaagc aaggttgaga acatctttgc caaagtaaaa
    10801 acgtttaaaa tgatttcaac aacctatcga aatcatcgta aacacttcgg attacgaatg
    10861 aatttgattg ctggcattat caatcatgaa ctaggattct agttttgcag gaagtctatt
    10921 atttggttag gtgaattagt gaagcgttta ggcaagtgtc tctggttacg acgtcatgac
    10981 ctctaaatcg attatattta ggggtcatga ctagtgaagc agttagctag ttcgcatata
    11041 agcggctagc gtctaacaat taggaacttt agttccaata actttaagat tacgacgttt
    11101 taggacataa atcgatcata tttatgtcct aaaactagtg aagcgcctag ccaaagtccg
    11161 aataggattt ggcgttagtt acttagattg ctttgcaatc aagtaacttt ggcgatttac
    11221 atcttctctg gcgcttctac tccaagcaag cgaagggctt ctttgagaac gactgcggtt
    11281 gcgtagctga gggctagacg gctgtcgcgt tctgggcttt catccaagat acgtgtatgt
    11341 gcatagtatt tgttaaagga ttgagccagg ctaattgcaa atttagcaat gatagaaggt
    11401 tcaaagttat ctgccgcacg gttgataata cgtgggaagt cttgaatgag tttaatgatt
    11461 tcccagcttt cagtatcatt caagctatag ttgccagctg tttctggttt gaaatcggct
    11521 ttgcgtaaga tagattggat acgagcgtag gcatattgaa cgtaaggtcc agtttcaccc
    11581 tcgaaggata ccatagcctc taggtcgaag tcgtatccat ttgtacggtc ggttttgagg
    11641 tcatagaatt taatggctcc aaccccaaca gcatgtgcta cctgatcttt attttccaat
    11701 tcaggatttt tagcctcgat ttggaccttg gcacggctaa cagcctctgc aacagtaggc
    11761 tctagcaaga tgacattccc tttacgagta gagagcttct tcccttcttt tgtaaccaag
    11821 ccaaaaggaa cgtgagtaat gtcgtcactc cagtcgtagc ccatctcttg caagacagct
    11881 ttgagctgtt taaagtgggc agattgttct tgaccaacga catagataga tttagcaaat
    11941 tggtattcgt ttttacggta aagggctgca gccaagtcac gtgtgatata gagagttgca
    12001 ccatcagact tcttgatgag ggctggatgt tcaattccgt atttctcaag attcacaact
    12061 tgggcacctt ctgattcaag aagtagtcct ttttcagaaa gaatgtctac aactgcatcc
    12121 atcttatcat tgtagaaggc ttctccgtta tagctgtcaa attcaacctt caattcattg
    12181 taaaggcggt taaattccac taaactttca tcgcggaacc attgccaaag agcgagagct
    12241 tcctcatctt cattttcaag tttacggaac cattcgcgcg cttcttcatc caagctaggg
    12301 tcattttcag cttcagcgtt gatgcggaca tagagtttaa ggagttcatc gattggatga
    12361 gcttttacag cttcttcgtc gccccatttt ttgtaggcaa caatcaacat cccaaattgt
    12421 ttaccccagt ctcccaaatg gttgaccttg accgtttgat aaccgatttt ttggaaaata
    12481 tgtgacaagc tatctccgat aacagttgaa cgcaggtggc caatagaaaa tggtttagcg
    12541 atattcggac tagacatgtc gataacaaca ttttcttgtt tgccaatatt ttggtcagca
    12601 tagtgttctt tttcagtggt aacagcttgc aatacttgag cagaaatggc agatttatca
    12661 aggaaaaagt taacgtaagg tcctgttgcg acaacttttt caaaggcttg gctgttcatt
    12721 ttttcagcca gttcagccgc aatcatttgt ggtgctttac gttcgacttt ggcaagagaa
    12781 aaagcaggga aagcgatgtc acccatttct gagtttttag gggtttccag taactttaaa
    12841 atagcctctt ggtccaggct atcaatgatg ctagccaatt cgctagcaat caattctttt
    12901 gtattcatta agagctcctt tttggacttt tctactattt taacacaatt ttaaagaaag
    12961 aagaaaaaat ttttgaaatc tcctgttttt ttggtataat atggttataa atatagttat
    13021 aaatatgcac gcaagaggat tttatgagaa aaagagatcg tcatcagtta ataaaaaaaa
    13081 tgattactga ggagaaatta agtacacaaa aagaaattca agatcggttg gaggcgcaca
    13141 atgtttgtgt gacgcagaca accttgtctc gtgatttgcg cgaaatcggc ttgaccaagg
    13201 tcaagaaaaa tgatatggtg tattatgtac tagtaaatga gacagaaaag attgatttgg
    13261 tggaattttt gtctcatcat ttagaaggtg ttgcaagagc agagtttacc ttggtgcttc
    13321 ataccaaatt gggagaagcc tctgttttgg caaatattgt agatgtaaac aaggatgaat
    13381 ggattttagg aacagttgct ggtgccaata ccttattggt tatttgtcga gatcagcacg
    13441 ttgccaaact catggaagat cgtttgctag atttgatgaa agataagtaa ggtcttggga
    13501 gttgctctca agacttattt ttgaaaagga gagacagaaa atggcgatag aaaagctatc
    13561 acccggcatg caacagtatg tggatattaa aaagcaatat ccagatgctt ttttgctctt
    13621 tcggatgggt gatttttatg aattatttta tgaggatgcg gtcaatgctg cgcagattct
    13681 ggaaatttcc ttaacgagtc gcaacaagaa tgccgacaat ccgatcccta tggcgggtgt
    13741 tccctatcat tctgctcaac agtatatcga tgtcttgatt gagcagggtt ataaggtggc
    13801 tatcgcagag cagatggaag atcctaaaca agcagttggg gttgttaaac gagaggttgt
    13861 tcaggtcatt acgccaggga cagtggtcga tagcagtaag ccggacagtc agaataattt
    13921 tttggttgcc atagaccgcg aaggcaatca atttggccta gcttatatgg atttggtgac
    13981 gggtgacttt tatgtgacag gtcttttgga tttcacgctg gtttgtgggg aaatccgtaa
    14041 cctcaaggct cgagaagtgg tgttgggtta tgacttgtct gaggaagaag aacaaatcct
    14101 cagccgccag atgaatctgg tactctctta tgaaaaagaa agctttgaag accttcattt
    14161 attggatttg cgattggcaa cggtggagca aacggcatct agtaagctgc tccagtatgt
    14221 tcatcggact cagatgaggg aattgaacca cctcaaacct gttatccgct acgaaattaa
    14281 ggatttcttg cagatggatt atgcgaccaa ggctagtctg gatttggttg agaatgctcg
    14341 ctcaggtaag aaacaaggca gtcttttctg gcttttggat gaaaccaaaa cggctatggg
    14401 gatgcgtctc ttgcgttctt ggattcatcg ccccttgatt gataaggaac gaatcgtcca
    14461 acgtcaagaa gtagtgcagg tctttctcga ccatttcttt gagcgtagtg acttgacaga
    14521 cagtctcaag ggtgtttatg acattgagcg cttggctagt cgtgtttctt ttggcaaaac
    14581 caatccaaag gatctcttgc agttggcgac taccttgtct agtgtgccac ggattcgtgc
    14641 gattttagaa gggatggagc aacctactct agcctatctc atcgcacaac tggatgcaat
    14701 ccctgagttg gagagtttga ttagcgcagc gattgctcct gaagctcctc atgtgattac
    14761 agatggggga attatccgga ctggatttga tgagacttta gacaagtatc gttgcgttct
    14821 cagagaaggg actagctgga ttgctgagat tgaggctaag gagcgagaaa actctggtat
    14881 cagcacgctc aagattgact acaataaaaa ggatggctac tattttcatg tgaccaattc
    14941 gcaactagga aatgtgccag cccacttttt ccgcaaggcg acgctgaaaa actcagaacg
    15001 ctttggaacc gaagaattag cccgtatcga gggagatatg cttgaggcgc gtgagaagtc
    15061 agccaacctc gaatacgaaa tatttatgcg cattcgtgaa gaggtcggca agtacatcca
    15121 gcgtttacaa gctctagccc aaggaattgc gacggttgat gtcttacaga gtctggcggt
    15181 tgtggctgaa acccagcatt tgattcgacc tgagtttggt gacgattcac aaattgatat
    15241 ccggaaaggg cgccatgctg tcgttgaaaa ggttatgggg gctcagacct atattccaaa
    15301 tacgattcag atggcagaag ataccagtat tcaactggtt acagggccaa acatgagtgg
    15361 gaagtctacc tatatgcgtc agttagccat gacggcggtt atggcccagc tgggttccta
    15421 tgttcctgct gaaagcgccc atttaccgat ttttgatgcg atttttaccc gtatcggagc
    15481 agcagatgac ttggtttcgg gtcagtcaac ctttatggtg gagatgatgg aggccaataa
    15541 tgccatttcg catgcgacca agaactctct cattctcttt gatgaattgg gacgtggaac
    15601 tgcaacttat gacgggatgg ctcttgctca gtccatcatc gaatatatcc atgagcacat
    15661 cggagctaag accctctttg cgacccacta ccatgagttg actagtctgg agtctagttt
    15721 acaacacttg gtcaatgtcc acgtggcaac tttggagcag gatgggcagg tcaccttcct
    15781 tcacaagatt gaaccgggac cagctgataa atcctacggt atccatgttg ccaagattgc
    15841 tggcttgcca gcagaccttt tagcaagggc ggataagatt ttgactcagc tagagaatca
    15901 aggaacagag agtcctcctc ccatgagaca aactagtgct gtcactgaac agatttcact
    15961 ctttgatagg gcagaagagc atcctatcct agcagaatta gctaaactgg atgtgtataa
    16021 tatgacacct atgcaggtta tgaatgtctt agtagagtta aaacagaaac tataaaacca
    16081 agactcacta gttaatctag ctgtatcaag gagacttctt tgacaattct ccactttttt
    16141 gctagaataa catcacacaa acagaatgaa aaggagctga cgcattgtcg ctcccttttg
    16201 tctatttttt aaggagaaag tatgctgatt cagaaaataa aaacctacaa gtggcaggcc
    16261 ttggcttcgc tcctgatgac aggcttgatg gttgctagtt cacttctgca accgcgttat
    16321 ctgcaggaag tattagacgc cctccttact gggaaatatg aagctattta tagtatcggg
    16381 gcttggttga ttggtgtggc cgtagtcggt ctagttgctg gtggactcaa tgttgtcctc
    16441 gcagcctata ttgcccaagg agtttcatcc gaccttcggg aggatgcctt ccgtaaaatt
    16501 caaacctttt cttatgctga tattgaacaa tttaatgcgg gaaatctagt cgttcgaatg
    16561 acaaatgata tcaaccagat tcagaacgtt gtcatgatga ccttccaaat tcttttcaga
    16621 cttcccctct tgttcatcgg ttcgtttatc ctagcggttc aaaccttacc ttctctgtgg
    16681 tgggtgattg ttctcatggt agtcttgatt tttggtttga ctgctgtcat gatgggaatg
    16741 atggggcctc gttttgccaa gtttcaaacc cttcttgagc gcatcaatgc cattgccaag
    16801 gaaaatttac gtggcgttcg tgtggtcaag tcctttgtcc aagaaaaaga gcaatttgct
    16861 aagtttacag aggtctcaga cgagcttttt ggtcaaaacc tttacattgg ttatgccttt
    16921 tcagtagtgg aaccctttat gatgttggtt ggttacgggg cggtcttcct ctctatttgg
    16981 ctggtcgcgg gaatggttca gtcggatccg tctgttgttg gttccatcgc ttcttttgtt
    17041 aattacctaa gccagattat ctttaccatt gttatggttg gatttttggg aaattctgtc
    17101 agccgtgcca tgatttccat gcgtcgtatt cgagaaattc ttgacgcaga gccagctatg
    17161 accttcaagg atatcccaga tgaagagttg gttggaagcc ttagctttga aaatgtgacc
    17221 tttacctatc caatggacaa ggaaccgatg ctgaaagatg tgagctttac tattgaacct
    17281 ggtcaaatgg ttggtgtagt tggagcgact ggtgcaggaa agtcaacctt ggctcaattg
    17341 attccacgtc tctttgatcc acagaacggg gccattaaaa tcggtggcaa ggatattcga
    17401 gaagtgagtg aaggaaccct gcgtaaaaca gtttccatcg ttctccaacg tgccattctt
    17461 tttagtggaa cgattgcaga taacttgaga caggggaagg gaaatgctac tctatttgaa
    17521 atggagcgcg cagccaatat tgcccaggct agtgaattca ttcatcgtat ggagaaaacc
    17581 tttgaaagtc cagttgaaga acggggaacc aatttctctg gtggacaaaa acaaaggatg
    17641 tcgattgcgc gtgggattgt cagcaatcca cgtattctga tttttgatga ttcgacctca
    17701 gccttggatg ccaaatcaga gcgcttggtg caagaagctt tgaataagga cttgaagggg
    17761 acgacaacca ttattattgc tcaaaaaatt agctcggttg tccatgcaga caagatcttg
    17821 gttctaaatc aaggacgatt gattggtcaa ggtacgcatg cagacttggt tgccaacaat
    17881 gccgtttacc gtgaaatcta tgaaacacag aaatgaaaga caaactataa gaaaagtcaa
    17941 tagttttatc taaactattt cttatttcaa tttgatgatt tggcgatgat tttagagcac
    18001 ggcaaaaggc ccttgaaaaa gtccattttt tcaaaggtaa tcctgtgtta atttcagaaa
    18061 ttacatcact ttttgttcgt caaatggcag ctctttttta ggatataaaa cagggttcgg
    18121 ataagttttt ttgcaaggtg gatgatggct acattgtaat gttttcctta ttctaactta
    18181 gtcttaagat aggccttaaa agcaggtgaa aagcgagcgc atgctttggc agcttgtatg
    18241 agtgcctacc gcagatgagg ggaaccccgt ttgatcattc ttccagctaa atcaatctga
    18301 cctgactgat aaatagaaga atccagtcca gcgaaagctt gtaattgagc aggattatca
    18361 aaggcatgaa tattttgaat ctcggctaaa atgaccgccc ctaaacgatt cccaatccca
    18421 gtaaccgtcg tgatgaccga atttaactca gccatcaagt cattgacaca tttttccgcc
    18481 ttgtcaatga gcctcttgta atgtttgatg ttttcattac acgagataaa acgtctatgc
    18541 gttatcaaac tcattaccaa ttaaaacaaa tgtggttaga tcctttcgga aattgtcaag
    18601 cgattggagg aaatgaacta atccacagcg gcttattcca agtataccac ttgggctttg
    18661 gcagtagcta actgcgctaa atataatata aggaggagta aaatgaagac agttcaattt
    18721 ttttggcatt attttaaggt ctacaagttc tcatttgtag ttgtcatcct gatgattgtt
    18781 ctggcgactt ttgcccaagc cctctttcca gtcttttctg gacaagcggt gacgcagcta
    18841 gccaatttag ttcaagctta tcaaaatggc aatccagaac ttgtatggca aagcctatca
    18901 ggaatcatgg tcaatcttgg cctgctggtt ttggttctat ttatctctag tgtaatatac
    18961 atgtgtctca tgacgcgcgt gattgcagaa tcgaccaacg agatgcgcaa aggtctcttt
    19021 ggtaagcttg ctcagttgac ggtttctttc tttgaccgtc gacaagatgg cgatatcctg
    19081 tctcatttta ccagtgattt ggataatatc ctccaagcct ttaacgaaag cttgattcag
    19141 gtcatgagca atattgtttt atacattggt ctgattcttg tcatgttttc gagaaatgtg
    19201 acgctggctc tcatcaccat tgccagcacc ccattggctt tccttatgct gattttcatc
    19261 gtgaaaatgg cacgtaaata caccaacctc cagcagaaag aggtagggaa gctcaacgcc
    19321 tatatggatg agagcatctc aggccaaaaa gccgtgattg tgcaaggaat tcaagaggat
    19381 atgatggcag gatttcttga acaaaatgag cgcgtgcgca aggcaacctt taaaggaaga
    19441 atgttctcag gaattctttt ccctgtcatg aatgggatga gcctgattaa tacagccatc
    19501 gtcatctttg ctggttcggc tgtacttttg aatgataagt ctattgaaac aagtacagcc
    19561 ctaggtttga ttgttatgtt tgcacaattt tcacagcagt actaccagcc tattatccaa
    19621 gttgcagcga gttggggaag ccttcagttg gcctttactg gagctgaacg aattcaggaa
    19681 atgtttgatg cagaggagga aatccgacct gaaaaggctc caaccttcac taagttgcaa
    19741 gaaagtgttg aaatcagtca tatcgatttt tcatacttgc ctgataaacc tattttgaaa
    19801 gatgtcagca tttctgcccc taaaggccag atgacagcag ttgttgggcc gacaggttca
    19861 ggaaaaacga ctattatgaa cctcatcaat cgcttttatg atgttgatgc tggtggtatt
    19921 tattttgatg gtaaagacat tcgtggctat gacttagata gtcttagaag caaggtggga
    19981 attgtattgc aagattcggt cttgtttagc ggaacgattc gagacaatat ccgatttggt
    20041 gtgccagatg ctagtcagga aatggttgag gtagcagcaa aagcaaccca cattcacgac
    20101 tatatcgaaa gtttgcctga taagtacgat actcttattg atgatgacca gagcatcttt
    20161 tcagcagggc agaagcaatt gatttcaatc gctcgaaccc tgatgacaga tccagaagtt
    20221 ctcattctcg atgaagcaac ttcaaacgta gatacggtga cagaaagcaa gattcaacat
    20281 gccatggagg tggttgtagc aggtagaact agtttcgtca ttgcccaccg cttgaaaacc
    20341 attctcaatg cagatcagat tattgtcctt aaagatggag aagtcattga acgtggtaac
    20401 caccatgaac ttttgaagct aggtggcttt tattcagaac tctatcacaa tcaatttgtt
    20461 ttcgaataag aaagaagttg tcctatgtgg gcagcttttt cttgtccata aaaaatgttt
    20521 atcacagcct taaaaaaaac atattagacg aaagtcattt tgagtgatat gataggacta
    20581 tcgttagcat tcgaaaggag aggcatcatg gctagaacgg ttgtaggagt tgctgcaaat
    20641 ctatgtcccg tagacgcaga aggcaaaatc attcattcat ctgtatcttg tagattcgca
    20701 gagatcattc gtcaagtcgg tggtctccct ttagtcattc ctgttggtga tgagtcagtt
    20761 gtacgtgatt atgtggaaat gattgacaaa ctcattttga caggaggcca aaatgttcat
    20821 cctcagtttt atggagagaa aaagaccgtc gagagcgatg attacaatct ggtccgtgac
    20881 gaatttgaat tggcactctt gaaggaagcg cttcgtcaga ataaaccaat tatggcaatc
    20941 tgtcgcggtg tccaacttgt caatgttgcc tttggtggaa ccctcaatca agaaatcgaa
    21001 ggtcactggc aaggactacc tttcgggaca tctcactcta ttgagacagt agaaggaagc
    21061 gtggtggcta agctatttgg gaaagaaagt caggtcaact cagtccatcg tcaaagcatt
    21121 aaagatttgg cacctaattt ccgtgtaact gctattgatt caagagacca aactattgaa
    21181 gcgattgagt ctatcgacga gcaccgcatt atcggtttac agtggcatcc agagtttctg
    21241 gttaatgaag aagatggcaa tttagaatta tttgagtatt tattgaatga actgtaacga
    21301 ttggaacatc tggtcgttct ttcttttatt ttttcaaaat ttttagaatg tggcatttta
    21361 cgcaaacgtt tgaattctga taaaaattgg agaaattcga caaaaaaact tgaaaaaaac
    21421 gaaggtaagc gttatgatag aaaagaagaa atattggagg aagaacatgt cacatattaa
    21481 atttgattat tcaaaagttt tagacaaatt tgttgcacca catgaagtgg aatacatgca
    21541 atcacaagta acagcagcag atgaattgat ccgtaaagga actggtgctg gtagcgactt
    21601 cttgggatgg ttggaccttc ctgaaaaata cgaccgcgaa gaatttgacc gcatcttgaa
    21661 agctgctgag caaatcaagt cagacagcga tgttttggtt gtgatcggta ttggtggatc
    21721 ttaccttggt gcaaaagcag caatcgactt cttgaatcac cattttgcta acttgcaaac
    21781 aaaagaagaa cgcaaagctc cacaaatcct ttacgcagga aactcaatct catctactta
    21841 ccttgctgac ttggtagagt atgttgcaga caaagacttc tcagtaaacg taatttctaa
    21901 atcaggtaca acaactgaac cagcgattgc tttccgtgtc tttaaagaac tcttggttaa
    21961 gaaatacggt caagaagaag ctaacaaacg tatctatgca acaactgacc gccaaaaggg
    22021 tgctgttaag gttgaagcag acgctaacgg ttggggaaca tttgttgttc cagatgatat
    22081 cggtggacgc ttctcagtat tgacagccgt tggtttgctt ccaatcgcag catcaggagc
    22141 tgacatcaaa gctcttatgg aaggtgcgaa tgcagctcgc aaagactaca cttcagacaa
    22201 aatctctgaa aacgaagctt accaatacgc agctgttcgt aacatccttt atcgtaaagg
    22261 ctatgcaact gagatcttgg taaactatga gccatcactt caatacttct cagaatggtg
    22321 gaaacaattg gctggtgaat cagaaggaaa agaccaaaaa ggtatctacc caacttcagc
    22381 caacttctca actgacttgc actcacttgg tcaatttatc caagaaggaa ctcgtatcat
    22441 gtttgaaaca gttgtccgtg ttgacaaacc tcgtaaaaac gtgcttattc ctactttgga
    22501 agaagacctt gacggacttg gttaccttca aggaaaagac gttgactttg taaacaaaaa
    22561 agcaactgac ggtgttcttc ttgcccacac agatggtgat gtaccaaaca tgtatgtgac
    22621 tcttccagag caagacgctt tcactcttgg ttacactatc tacttcttcg aattggcaat
    22681 tgccctttca ggttacttga atgctatcaa cccatttgac caaccaggtg ttgaagctta
    22741 taaacgtaac atgtttgccc ttcttggaaa accaggattt gaagaattga gcaaagaact
    22801 taacgcacgt ctataataga agaaaagagt ggtttgccca ctctttttac tctctttatc
    22861 catagaaatt ggactcagcc aagacttgtg atataatata gaaagcaaaa aggcagacgc
    22921 ctagataata ggagaaacta tgtcaaaaga tatccgcgta cgttacgcac caagtccaac
    22981 aggactacta cacatcggaa atgctcgtac agcattgttt aattacttgt atgcgcgcca
    23041 tcatggtgga acatttctca tccgtatcga agatactgac cgtaaacgcc atgtcgagga
    23101 tggtgaacgt tcacaacttg aaaaccttcg ctggttaggc atggattggg atgaaagtcc
    23161 agaatcacat gagaattatc gccagtctga gcgtttggac ttgtatcaaa aatacattga
    23221 ccaactatta gctgaaggaa aagcctataa atcttacgtt acagaagaag agttggcagc
    23281 tgaacgcgaa cgccaagaag tagctggcga aacaccacgc tacatcaatg aataccttgg
    23341 tatgagtgaa gaagaaaaag cagcttacat cgcagaacgt gaagcagcag ggatcatccc
    23401 aactgttcgt ttggctgtca atgagtcagg tatctacaag tggcatgata tggtcaaagg
    23461 cgatatcgaa tttgaaggtg gcaatatcgg tggtgactgg attatccaaa agaaagacgg
    23521 ttacccaact tacaactttg ccgttgccat cgatgaccat gatatgcaaa tctctcatgt
    23581 tatccgtgga gacgaccata ttgctaacac accaaaacag ctcatggttt atgaagcact
    23641 tggttgggaa gctccagagt ttggtcacat gaccttgatt atcaactctg agactggtaa
    23701 gaagttatct aaacgtgata ctaatacact tcaatttatc gaagattacc gaaagaaagg
    23761 ttaccttcca gaagcagtct ttaactttat tgctcttctt ggttggaacc caggtggtga
    23821 agatgagatt ttctctcgtg aagaactcat taaacttttt gatgaaaacc gcctcagcaa
    23881 gtcaccagca gcctttgatc agaaaaaact agactggatg agcaatgatt atatcaagaa
    23941 tgcagacctt gaaaccatct ttgaaatggc aaaaccattc ttagaggaag caggccgttt
    24001 gactgacaag gctgaaaaat tagttgagct ctataaacca caaatgaaat cagtagatga
    24061 gattatccca ttgacagatc ttttcttctc agatttccca gaattgacag aagcagagcg
    24121 cgaagtcatg acgggtgaaa cagttccaac agttcttgaa gcattcaaag caaaacttga
    24181 agcgatgaca gatgataaat ttgtgacaga aaatatcttc ccacaaatta aagcagttca
    24241 aaaagaaaca ggtattaaag ggaaaaatct tttcatgcct attcgtatcg cagtttcagg
    24301 cgaaatgcat gggccagaat taccagatac aattttcttg cttggacgtg aaaaatcaat
    24361 tcagcatatc gaaaacatgc taaaagaaat ctctaaataa agaggataca ataatggaca
    24421 tctgggaaaa gatgtacgaa gaagcacaga aactatacaa tccacatgaa gtatcagact
    24481 ttgtttatgc caatcatgtt gtagctgcag tagaagcaga agatggacaa atatttacag
    24541 gattctgtat ggagggaacc tgtggtgttt tccatctctg cgcagaacgg gcggccctct
    24601 tcaatatgta ccaattttca ggacaaacta aggttaagaa agtattagcc tttcgagaca
    24661 aaccacctta tggtggaagt tcagccatgc cttgcggtgc ttgtagagaa ttccttttag
    24721 agcttaatgc tgaaaataaa gatgcagaat tcatgatgga ctataatata agaaaaacag
    24781 ttaaagtcgc agaactaatc ccttattggt ggggagaaga acgtgcttct aagtttaatg
    24841 agcgatagaa gagtcagtat aattctggct ttttttacta taagttgaaa aaata
//
LOCUS       DAVMBH010000029        23795 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVMBH010000029 DAVMBH010000000
VERSION     DAVMBH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23795
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.029"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(344..1540)
                     /gene="tuf"
                     /locus_tag="VYP30_001335"
     CDS             complement(344..1540)
                     /gene="tuf"
                     /locus_tag="VYP30_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1808325.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2451..3320)
                     /locus_tag="VYP30_001336"
     CDS             complement(2451..3320)
                     /locus_tag="VYP30_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1808326.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLSIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3543..4220)
                     /locus_tag="VYP30_001337"
     CDS             complement(3543..4220)
                     /locus_tag="VYP30_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1808327.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANAILASAGIMTLLAGLGLGFF
                     KKKEDEK"
     gene            complement(4192..5283)
                     /locus_tag="VYP30_001338"
     CDS             complement(4192..5283)
                     /locus_tag="VYP30_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1808328.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEVDTNSASLTGNIVSKGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTIITVRMLRKSGSQNSNLY"
     gene            complement(5394..5648)
                     /locus_tag="VYP30_001339"
     CDS             complement(5394..5648)
                     /locus_tag="VYP30_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808329.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5988..6434)
                     /locus_tag="VYP30_001340"
     CDS             complement(5988..6434)
                     /locus_tag="VYP30_001340"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808330.1"
                     /translation="MDETGIDRYLYRPYARAPRGEKVYEKISGRRFERTSIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNASFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDVLREVSTIFECLECFFKTR"
     gene            complement(6507..6833)
                     /locus_tag="VYP30_001341"
     CDS             complement(6507..6833)
                     /locus_tag="VYP30_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808331.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7067..8785
                     /locus_tag="VYP30_001342"
     CDS             7067..8785
                     /locus_tag="VYP30_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1808332.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            8896..9243
                     /locus_tag="VYP30_001343"
     CDS             8896..9243
                     /locus_tag="VYP30_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1808333.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9522..10358)
                     /locus_tag="VYP30_001344"
     CDS             complement(9522..10358)
                     /locus_tag="VYP30_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1808334.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10371..11000)
                     /locus_tag="VYP30_001345"
     CDS             complement(10371..11000)
                     /locus_tag="VYP30_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808335.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11010..11651)
                     /locus_tag="VYP30_001346"
     CDS             complement(11010..11651)
                     /locus_tag="VYP30_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808336.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11797..13026)
                     /locus_tag="VYP30_001347"
     CDS             complement(11797..13026)
                     /locus_tag="VYP30_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1808337.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLKQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13016..14182)
                     /locus_tag="VYP30_001348"
     CDS             complement(13016..14182)
                     /locus_tag="VYP30_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1808338.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14326..15339
                     /locus_tag="VYP30_001349"
     CDS             14326..15339
                     /locus_tag="VYP30_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1808339.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15384..15803)
                     /locus_tag="VYP30_001350"
     CDS             complement(15384..15803)
                     /locus_tag="VYP30_001350"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1808340.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15814..17220)
                     /gene="atpD"
                     /locus_tag="VYP30_001351"
     CDS             complement(15814..17220)
                     /gene="atpD"
                     /locus_tag="VYP30_001351"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1808341.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17306..18184)
                     /locus_tag="VYP30_001352"
     CDS             complement(17306..18184)
                     /locus_tag="VYP30_001352"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1808342.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18200..19705)
                     /locus_tag="VYP30_001353"
     CDS             complement(18200..19705)
                     /locus_tag="VYP30_001353"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1808343.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19720..20256)
                     /locus_tag="VYP30_001354"
     CDS             complement(19720..20256)
                     /locus_tag="VYP30_001354"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1808344.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20256..20750)
                     /gene="atpF"
                     /locus_tag="VYP30_001355"
     CDS             complement(20256..20750)
                     /gene="atpF"
                     /locus_tag="VYP30_001355"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1808345.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20764..21480)
                     /gene="atpB"
                     /locus_tag="VYP30_001356"
     CDS             complement(20764..21480)
                     /gene="atpB"
                     /locus_tag="VYP30_001356"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1808346.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21515..21715)
                     /locus_tag="VYP30_001357"
     CDS             complement(21515..21715)
                     /locus_tag="VYP30_001357"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1808347.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21790..22743)
                     /locus_tag="VYP30_001358"
                     /pseudo
     CDS             complement(21790..22743)
                     /locus_tag="VYP30_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155340.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23174..23572)
                     /locus_tag="VYP30_001359"
     CDS             complement(23174..23572)
                     /locus_tag="VYP30_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808348.1"
                     /translation="MENKESYKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     GFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT         7062 a         5089 c         4331 g         7313 t
ORIGIN      
        1 atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata gatgttactg
       61 acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgc agctaacttt
      121 ctataacaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat cgatttctaa
      181 caatgtttta gaagtagatg tgtactattc tagtttcaat atattatagt ttgctctttg
      241 attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca agattctttt
      301 agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct tcgatttctg
      361 taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta gtaccttgtt
      421 ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca ggcattacca
      481 tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg aagtagaatt
      541 gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta gtaaggatgt
      601 agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg ataacttgtc
      661 cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta tctccagcaa
      721 gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct ttttgagttt
      781 cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca cggtcgatac
      841 gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact ggaagaagca
      901 atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg ttcatcaatt
      961 ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct gaaccttgga
     1021 taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg atttccattt
     1081 caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg aagacgataa
     1141 ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt ggcattggtc
     1201 cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca gtgatcatgt
     1261 ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt ttttcagttt
     1321 cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct ggagcagcat
     1381 cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt gccaaaacag
     1441 ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata gtaccaatgt
     1501 taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa gcctccaata
     1561 aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac tattttatca
     1621 aatttcagct aaattgcaag tgttttacaa tgtttttgtg aattattctt ggtaaaaatt
     1681 taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc agcattatcc
     1741 atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa tgaaacaaga
     1801 atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagatgt
     1861 gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa caacctgcgg
     1921 ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat aaaacgataa
     1981 caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta atcgcttatt
     2041 ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc aattcctcac
     2101 aatgtttgag aaagaagggg ggactattcc aacttcaacc cactataaag cagacttaca
     2161 agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa tttgattgga
     2221 gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt caactgcaac
     2281 ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac tgctggagag
     2341 gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa ccagtctgat
     2401 cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc ttagagataa
     2461 aggaatttaa atacagctac tgccgcaatt gctgctgcga taggtgctac tactggtacc
     2521 caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt tggaaggaaa
     2581 gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc tgtaggtcct
     2641 ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc cacagaaagt
     2701 cctgaagcag tgtgtggagc cacctgtgct ttaatagaca agtcagaaaa atcaactgtt
     2761 tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc aaagaagttt
     2821 ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaattc attaatcaaa
     2881 ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact tgaaatagtt
     2941 gagaaagttc ccaagatgtt atttgggttt tcagttttca agtagaatgg acggtatgtt
     3001 gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat gtaaggtacc
     3061 acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc agggttgatg
     3121 tgattcccag atacgttacc aaacatcaag gcagggatca taacccccat accataacca
     3181 acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc aacgttggca
     3241 actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt ggcatacttc
     3301 agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat attccttatt
     3361 ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa aaaataggat
     3421 tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa agacctcatt
     3481 ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga ttctaaaatc
     3541 tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc taacaaggtc
     3601 atgataccag cactagccaa gatagcatta gcttctgtac ctgtgtttgg caattcctct
     3661 ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt ttcagttttt
     3721 ggagtacctg gttctggagt tggctctggt attggagtct cttgatttgg tagttctggg
     3781 tttggtgtcg gaacacttgg atgctctgga tttggttgtg ggattggttt ttctggagtc
     3841 ggttcacctg gagtacctgg ttcctgagga cttggaattt ctggtttttc tggagttggt
     3901 ttatctggtg ttgataaacg gtcatacctt accgttattt ctttatcact agagtctgac
     3961 gtaacttctt gtgattcaac tgttggaata tctggatctt tgtacttgtc aatcttacca
     4021 gatacaacct cgtcccagtt tcctgttgtc cattcaccgt aggttacaac tcccgtgacc
     4081 ttgttctcag tttttgtacg gcttaaggtt acaggttgaa caacatcttc ttttacattt
     4141 tggttcgtaa ctttatcaac gtaatgaatg atacgcgtta tagtcttcgt ctcagtagag
     4201 gttgctgttt tgggaaccac ttttcctcaa cattctcacg gtaataatag tcaactgttg
     4261 caccgtcttc tggtacgcat ttgcaggagt tgctaccaag gtgtatgttg ttttccttgt
     4321 gataactcgg tcttctttgt cctcagttgt tgttttccct tcaatagttt ttgattctgt
     4381 ggtatactca gaacctatcg ctaaatcagc ttttataaca gactctgcca acttctcttg
     4441 gctaccttct ttatagtaat tggctgttac tgtagcagtg gttggcgctt cgctttctct
     4501 ataaactaag gtcactgttc tacctttgct tacaatattc ccagttaaac ttgcagaatt
     4561 tgtatctact tctttaaaag tataatattt tccgtcagta gtagtcatgc tactgagttt
     4621 tttatctgtg acattatagc tggtaccaat cagttgtttt ttattggtaa tgtaggttcc
     4681 gtcactttct ttttctccaa ttccagtatc atttttcaat gatagcaaac gcccttgttc
     4741 atcaacatag cgaactttca cattttctga gattagttct gccaattctg aggttttttt
     4801 ctttttcttg atttcttcgg ttattttccc tttctcttct tcgggaatat ttagttttgg
     4861 aatgattttt tcaacaacgg ttcgtgatgg ttccacagta tcttggatga ctgaaaagtc
     4921 agctagaatt gggagattat actgaacacg gtgactttga gtgtttactc ctactctttc
     4981 attattctct gaaaatactt gtacggtata agaaacaaca tcttttccta atagaacatc
     5041 cccagtagag aaatagccgc cttttcctag tttgctatct ccagagccca cttctttcct
     5101 aatcttatca gatagttttt taccagtcag tacattcgtt cgcacaatcc ctttgtctac
     5161 ccctacaaag tgggagaatt ttttgaactc ttcagaacca gatctagccc aaccattatt
     5221 aagggcattt gcttttgtat ttgtattctc tctcaaaggt ttggcgatta gaattatatt
     5281 catcggcgct tagagttgct gctatatctg actcttgaat accaacttcc ttactaccat
     5341 ttctagcggc agtatatgtg tatttatctg tttctacttc tagctgatta tccttaacat
     5401 gataggtaat tttctcctgg tataagagtc ttcagtagtt tatatgctct gtcatcatct
     5461 ttagctttag aagcagctga gtttagccaa gttggggtat taggagtatc tttatcagcc
     5521 tgtttcaaga cattattcaa gtcatttgct agcctattgg ttatcctcac tgtgaaagtt
     5581 ttcttccagt ctgaaccact tttattagac ttagatatgc tcatgaaatc ctggtcaaca
     5641 ttcaacacaa tatcgcctta ttttttagca tcttccgttg cttctgcttc aaattgatca
     5701 tggagttttt gttgctctgg tgtatagttt ttttatttac acgatttaat gtactatttt
     5761 ttattttagt attaagaact ccattaatac gatttttaaa ctctgcttca aaaaatccct
     5821 taatttgttg gtgcgcaagt tcaacattca aacctttctt atacaagtct tcattctgaa
     5881 cgatttcggc tacacggtga atggtttgat cgtataccgt cttctcttaa ccagcagtat
     5941 ccttagtttt aatgactact cgataggttc ctttagaacc gttatagtca tctagtttta
     6001 aaaaagcatt ccaaacattc aaaaatagtt gaaacttccc ttaatacatc cgtcactttc
     6061 tttttcaaga tagcccaagc ttgctcaata ggattcaaat ctggtgaata aggtggtaga
     6121 ggtaagaaaa agtgtttatc ttggatgcag agttcatcca aaatgttctt gggatgaaaa
     6181 ctagcattgc ccatgacaat aacatgaggt gtcttcaaag caggtaggag ttgcgttttg
     6241 aaccactcca caaagaaatc gcttgtcatg cttttcttgt aaatcatggg agctataaac
     6301 tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa aacgacgtcc gctaatcttt
     6361 tcatagactt tctcccctct aggagcccgt gcataaggac gatagagata gcggtcgatt
     6421 cctgtttcat caatataaac aggtgctagg tgctttaaac tattaaaatt cttaagaaat
     6481 aaggctactt ttctgggtct tgttccttaa agatcgtcat ctttttttaa agtgacctta
     6541 atctgcttta aagctgccca tactgaagga acagcacaat caaaatgtgc cgcaatttcc
     6601 cgtaaaaaag catctggatg agcctctaca aaggctttca attcttctaa agggatctta
     6661 cgctttttga cgactcgctt tttccgctct aagttccttt gttcacgtct ttcttttccc
     6721 acgtgaagag agttctgacg ccaacaccaa aaaactttgg ccgcctcgac atgtctgtgc
     6781 cctcctttga tggaatctaa tgctccttgt ttaaaatcag tattatatgc catagcttta
     6841 ttagaccatg cttattttaa actaagcaac tatatcaatg ttttgttatg agaagactta
     6901 ctttttttac tgaaattgaa tttttcctag cctcaacatc atataacccc aaaattcaat
     6961 ctgacctggt ttgaatagat gttcgaagca gataaggttt tactaaaact aaaaaaaatg
     7021 atataatcaa attgattaaa tgttttaaaa ataaaggaga atttgaatgt cttaccaaga
     7081 aaattaccag aaatgggttg attttgtgga gcttcctgac taccttcgtc aagatttgga
     7141 aaatatggac gaaaaaacta aggaagatgc cttctataca aatcttgaat ttggtactgc
     7201 aggtatgcgt ggcttggttg gtgctggtac aaaccgtatc aacatctacg ttgttcgcca
     7261 agctactgaa ggattggctc gtttgattga gtcaaaaggt ggaaacgaga aagaacgcgg
     7321 tgtagcaatt gcctacgata gccgtcactt ctcacctgag tttgcctttg aatctgcggc
     7381 agttcttgct aaacacggca tcaaatctta cgtatttgaa agccttcgtc cgactccaga
     7441 actatcattt gcagttcgtc atctcaactg tttcgcaggt atcatggtca cagccagcca
     7501 caaccctgct ccatttaacg gttacaaggt ttacggtgaa gacggtggac aaatgcctcc
     7561 acacgatgcg gacgctttga ctacttatat ccgtgcaatc gaaaacccat ttgcagttga
     7621 agttgctgat gtggaaactg aaaaagcttc tggcttgatt gaagttatcg gcgaagctgt
     7681 tgacgtagaa taccttaaag aggttaagga cgtaaacatc aacccagcct tgattgaaga
     7741 atttggtaaa gacatgaaga ttgtctacac accacttcat ggtactggtg aaatgttggc
     7801 tcgtcgtgct cttgcccaag caggatttga ctctgttcaa gttgttgaag cgcaagcaac
     7861 tgctgaccca gacttctcaa ctgtaacatc tccaaaccca gaaagccaag cagcctttgc
     7921 ccttgctgaa gaacttggtc gtcaagttgg tgcagatgtt cttgtcgcaa ctgacccaga
     7981 cgctgaccgt gttggtgttg aagttcttca aaaagatggt agctacctca acctttcagg
     8041 taaccaaatc ggtgctatca tggctaaata catcttggaa gctcacaaaa acgctggaac
     8101 tcttcctgaa aatgccgctc tctgcaaatc tatcgtttca actgacttgg taacgaagat
     8161 tgctgaaagc tacggcgcaa ctatgttcaa cgtcttgaca ggtttcaaat ttatcgctga
     8221 aaaaatccaa gaattcgaag aaaaacacaa ccacacttac atgatgggat ttgaagaaag
     8281 cttcggttac ttgattaaac catttgtacg tgataaagat gccatccaag ccgttcttgt
     8341 cgttgctgaa cttgctgcct actaccgttc tcgtggtttg acacttgctg acggtatcga
     8401 agaaatctat aaagaatatg gctactacgc agaaaaaaca atctctgtta ctctttcagg
     8461 tgtcgatggt gctgaacaaa tcaaagcgat tatggctaaa ttccgcaaca atgctccaaa
     8521 agaatggaac gcaacagcta tcactgtcgt agaagacttc aaggcacaaa ctgctactgt
     8581 tgctgacggt actgttacaa acttgacaac tcctccaagt gatgtgttga aatacacact
     8641 tgctgacggt tcatggattg ccgttcgccc ttcaggtaca gaaccaaaaa tcaagttcta
     8701 cattgcagtt gtaggggaaa ccaacgaaga atcgcaagct aagattgcta acatcgaagc
     8761 agaaatcaat gcatttgtaa aataaagacc tataaaagat gagaccaacc aacctcatct
     8821 tttttcgtat caaatctaag caattttaga aactttatgg catactagac ttatcaatga
     8881 aagcgaggta atctcatgga acaattttta gataacatca aagaccttga agtcactaca
     8941 gttgtgcgtg cacaagaagc tcttgataaa aaagaaactg caaccttctt tatcggtcgc
     9001 aaaacttgcc cttactgccg taaatttgca ggtacattgt caggtgtcgt agctgaaacc
     9061 aaagctcaca tttacttcat caatagtgaa gaaccaagcc aactcaatga tttgcaagca
     9121 ttccgctcac gctatggaat cccaactgta ccaggttttg ttcatattac agatggacaa
     9181 atcaacgtcc gttgcgactc ttcaatgtca gcacaagaaa tcaaagattt cgcaggattg
     9241 taaaaaatca gctaacaagt cttaaaatca caaaaacgca taatgtaagg tgcaaaaacc
     9301 ttgatattat gcgttttatt gttcctaaaa cagttacatc agcatttcat tacagaacat
     9361 tttaattttg gaagtcaaat caatttttaa caatgtttta gaaatcacag tgggctattc
     9421 catattcaat tatccagatt caatcgctat tatcgttttc ctagattaca aaaaaaactg
     9481 cgttttgcta atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact
     9541 tctttggttg ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc
     9601 ttgtaaagac tagaaaaagc ttcatttatc ttcttaacca aggttgtatc ttccttacgg
     9661 gctccaaccg caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa
     9721 acaccttctg cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt
     9781 cgatcgtttt tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta
     9841 ttagcgacaa tattcttcaa aatttctgga tttgcttcaa agtccgcata accagatgaa
     9901 ccagcttgag ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat
     9961 ttcttcgtaa ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca
    10021 cggcgttcgt ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat
    10081 tcagcttctt tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca
    10141 aaaacagctg tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat
    10201 cccattggaa caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt
    10261 gaccaattat ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca
    10321 gtcatcagac tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt
    10381 tctactttca ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca
    10441 atctgggtca tcccaagttc cctattttgc aagattagct tctccacttc caaacgcaat
    10501 tctggatcca gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata
    10561 gcacgcgcca aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggcctct
    10621 gcgtgtcctc ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc
    10681 tgcttcattc ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga
    10741 ggaaatagtt gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatcc
    10801 agctctaaag gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacccgca
    10861 agcatacgta aaagagtcgt cttacctcca ccagaaggtc caacgatagc caggatttgc
    10921 ttttcaggaa tacttagact gaaattagac aggatttgtt tgtctccaaa gactttattg
    10981 atatttcgta attctaacat ggcagcctcc tatctataat aactatactt cttctcaact
    11041 tttttggaaa taattgtcac aatcccaatc aaaatcaaat aaatggctcc tgccaagaac
    11101 ataggaacta gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa
    11161 attccgagag catagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca
    11221 ctaggaagaa cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg
    11281 ctaaacttca agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca
    11341 cggaaaattt ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga
    11401 aggcggtcta aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag
    11461 agtaaggggg ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc
    11521 caatggactt gcaaggcaaa ggcaatcaaa acgcccaagg gaatcgaaaa tagcaagacc
    11581 agtgcaaaga cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat
    11641 aaataagaca tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag
    11701 attaccaagt atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa
    11761 aagagataaa ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg
    11821 catttgcaca tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc
    11881 aaaatgtccc aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt
    11941 caaatctcct gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg
    12001 ataagaacga gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc
    12061 tagaatatcc tcataacgct cctgcttcag ataaatagtg gctaaacgaa gcaagatttc
    12121 ttctgtatcc tcagcgtctt cttttgcagc aagaagataa ttttctgcac cactagcatc
    12181 atgcaattca taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt
    12241 ctctaatcct tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc
    12301 ctgactgtac ccatactcat agccttcaaa gtcaggagaa atggtatcaa gctgcttaaa
    12361 gtagagggtg gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc
    12421 tgttaagtca tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa
    12481 tttccctaac tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc
    12541 ataaatcgag cgattatcta actgggcata agcttgaata gccgcttggt aattttccaa
    12601 ctcactatcc aactctgcca aacccaacat caagagagaa tcctctgagt aggtcaaggc
    12661 ctccaataat ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt
    12721 cagagccaaa gacgagacat accagtcact atcagcttgg atttcctcaa gataggtaaa
    12781 ggcttcttct atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg
    12841 aaaatcctct acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc
    12901 aagataagtt gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa
    12961 ataatgctca gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt
    13021 gttcactctt gacttcctca ccctctaatt catatagacc actgactacc ttataccatt
    13081 cgaaaatggc tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc
    13141 cccagatacc aaacatagat cctgaagtta acaaaacaaa gagaacatta atagggtgga
    13201 tgtttaattg acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta
    13261 caataaagac aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta
    13321 gggcaggaag catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag
    13381 taacccccag cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta
    13441 ctgctacaat aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca
    13501 catctgatag aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat
    13561 agttacgcaa gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca
    13621 aggcaacaat cacttgagaa gctccgctaa taaaggcact cacccagttg actgcctgag
    13681 atgaaacctt acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta
    13741 attgaggtct gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta
    13801 tatcttctaa gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg
    13861 gaatggcgac tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga
    13921 tagctataac acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat
    13981 aatataacaa accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag
    14041 gtgaaaatag aaaactaatc ttacttaaaa taaaaagatt cagtcccaat aataaggtta
    14101 ctaaaaatac cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa
    14161 aatgtttctc tttttgctcc ataaatactt cctttctatt gttctctcat tataccattt
    14221 ttaaaacaaa ataactcttt tttaaagtgc ttacatctaa ttggatatct ttaatttact
    14281 tgtttttgtg atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt
    14341 tattttggaa cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca
    14401 gaaactggtc agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt
    14461 gcctttgacc agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt
    14521 gcagcctatc aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac
    14581 tgttatgttg ctgtcgatga aaagcgtgat ttggtttacg cagctaacta tcacaaggga
    14641 caagtccttg tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa
    14701 cacagtggcc aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta
    14761 acacctgacc actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac
    14821 ctcgatcaag aaggaaagtt atctaagctc tatacctatc acagcaagcc aggagcaggc
    14881 tcacgccata tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat
    14941 agtactatcg aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt
    15001 tcaactttac cggaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa
    15061 gacggtaaat acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc
    15121 cttgcggacg gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt
    15181 gattttgatt tgacacccga ccaaaaattt ctcattgttg tccatcaaga ctctgacaat
    15241 gcaactgtct ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc
    15301 catgttcccg aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt
    15361 ggtattttca agttcatttt ttcttatagt ctatttccga cattaatacg gttaatagca
    15421 cgttgcaaag caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct
    15481 tcaattgcac gttctgcacg aagtttggca cgttctgcac gactgatatc gatatcacga
    15541 gcacgttctg cagagtcagc gacgattgtg atcatatcat tggcaatttc aataacgcca
    15601 ccgtttactg caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca
    15661 tcaactgcta aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc
    15721 agagttcgaa ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg
    15781 atctggacag ttaactgagc catagatcac ctcttaaaat cccatttttt cagcttttgc
    15841 aatcacatct tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt
    15901 accatcaagg atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg
    15961 ctgaccagta aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg
    16021 ggcgcgagca accaaggtct tttcttcatc agaaagttca tccataccaa ggatagcaat
    16081 gatatcttgc aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata
    16141 gtgctcttct ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac
    16201 ggctgggtag atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg
    16261 agcgaaggct gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg
    16321 gatagaggtt acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc
    16381 cgtagcaagt gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac
    16441 ttctgaacca gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc
    16501 ttccacatca cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc
    16561 tcctggtggc tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc
    16621 tttcatttcc cagtaaaggt cattcccctc acgagtacgt tccccaacac cagcaaatac
    16681 tgaaatacca ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacagtttt
    16741 accaactccg gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag
    16801 gtcaataacc ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt
    16861 tggagctttt ttatgaattg gctgacgctc tgcgtcttct gtaaaaggag cttccaagtc
    16921 aatggtatct cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga
    16981 gattggacga cctgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat
    17041 ggcgatagta cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt
    17101 ttttctttcg tcatttttgt agacgacaag tgcattgtta atctcaggaa gtttttcccc
    17161 tgctgcaaac aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat
    17221 ctccttctcc tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc
    17281 attttcatac gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg
    17341 taatttcttg tgtaatcgcc gcctgtctgg cacggttata ctgaattgtt aaatcattga
    17401 tgactttctt agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag
    17461 ctgtcttggc atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact
    17521 gctccagaat ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg
    17581 cttcatttgg atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta
    17641 gcgtattgac atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca
    17701 tttcaacagt ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgccaagc
    17761 cacgtaattc ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac
    17821 cgatacagat catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa
    17881 cagctttcaa aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga
    17941 tatagcctgt cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc
    18001 cattaccatg aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt
    18061 tgcgagcagc ttcttcagag cgacctaact tagcagccga taccatttgc atggcattag
    18121 tgatttgact cgtatttttt gttgaggcga tttttgtttt aatatcattt agagacactg
    18181 ccatctgaca cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag
    18241 catccaagac tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg
    18301 gatgttgagc atcaaagaag gcatggaact cttcctcgaa acgaacaata tcatctactg
    18361 gaacagtatc caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag
    18421 gtaatggttt gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact
    18481 tagcctgtgt tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt
    18541 atgaagcaag gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag
    18601 aaccacctac acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga
    18661 agaggccatc gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat
    18721 aggctgagat atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac
    18781 caagttcatc agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat
    18841 cccctgggaa ggcttcacga cctggaggac gacgaagcaa gagcgacagt tcacgataag
    18901 ctaccgcttg ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa
    18961 attcttccgc catagcgacc ccagtataag gagctaggaa gagcaatgga gatggttgtg
    19021 aagcagaggc tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta
    19081 cttgcgtacg aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt
    19141 gatctttttg gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac
    19201 cgataatcaa ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac
    19261 cagtttgcaa tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta
    19321 ctggacgagt tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat
    19381 ccacaacacg accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc
    19441 ggattgtatc gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg
    19501 ttgactccaa gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac
    19561 tcatgacatt ttcaaggccg tgagcacgcg cgataccgtc cccgatatag gttacaacac
    19621 ctgtttcagt cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc
    19681 tgatttcttg tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac
    19741 aactttaagt tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa
    19801 accaccaatg agactttcat cgatttgttc ttttacactc cttactttca gagacatttt
    19861 tttctcaatc aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt
    19921 aatcgtcact tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac
    19981 atcataaaaa agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa
    20041 aggcgacaca gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc
    20101 cacttgtttt aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa
    20161 gtctgaaaag atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct
    20221 gtatttttca attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata
    20281 tactgatcaa tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca
    20341 gctaagctga tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta
    20401 ttttgagcaa tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct
    20461 gctaagatat tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta
    20521 gcttctttac ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt
    20581 tgacgggctt cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa
    20641 atgcctgtaa tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag
    20701 ccagtgatta aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc
    20761 tttctattcc tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa
    20821 aacataagct tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc
    20881 aaaggctact ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat
    20941 gacctctcct gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa
    21001 ttcttccaag atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt
    21061 tttaaatcca cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa
    21121 ggttaagtca tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt
    21181 ttgaagcttt gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag
    21241 gaaaaagagt gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat
    21301 aacaaagtca tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt
    21361 gcggcttgcc caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa
    21421 catagtcaga ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat
    21481 ctaaaatcct cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa
    21541 gagttacaaa gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaact
    21601 cagaaagcat atctggttgg cgtgctactg atttaaacag tccattcatc aataaacctt
    21661 caccgacaga tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa
    21721 attctccttt aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac
    21781 ttttaaccgc tattggaagc gtttaataaa aattatttcc attttgctaa atttcaagtt
    21841 caagttagcc atccaaaagt cttctctggg tgacttgtag tccaagcatt ttttaggata
    21901 gttgttaatc cacttttcga tgaatgcgac ttctttggga gtcattttct tggttccctt
    21961 aggtaaccat ctacgaatga gcctgttgtg attctcatta gttccccttt cccaagaggc
    22021 atagggatgt gcataataaa tgtgctcctc agaaaataca ttagacaagc gattgaattc
    22081 cgttccatta tctgccgtga tggaaagaat cttgtgttgt tttaagatga gttttagagc
    22141 ctgattgacc acctcagcac ttttatttgg aatcaatcgg atgatctgat gtctactttt
    22201 tcgatccgtc aagacaagca agcagtagtt tttcgctctc gtaagtagaa ctgtatcaat
    22261 ctcataatgc ccattctcca agcgaaaatt gatagcttca agccgctgtt cgatggattg
    22321 accagcaggt ttaaagttgg tgctggcctg tttcttaagc gcttttcctt ttctagggta
    22381 aagcagatcc tgcttgcttt accccaattt tccatgatga atccaatagt aaatggttga
    22441 aattcccacg ttaacccctt tagccataac catcatttca ggcaaaaatt tttggttatg
    22501 atagtggaga atcttttcct ttagttcctt ggtcacgctt gatctcttga ccgagtgctt
    22561 gcgattattt tcataagact gttgagcata gtcggcagaa taaacctctt tgaagcgccc
    22621 ttttccaaga cattttcgga ctgtcctacg cttgatttca gtgtggatag tttgaggagc
    22681 ttttccaagt agagaggcaa tttctctatt tgatttccct ttgttcgcct tttgtagtat
    22741 aatggttttg catctctgtg cctttcttgt gtttgtggtt gaacaacaag tataacacaa
    22801 aggtgttttc ttatgcctac aagagctttc attatttcca ttttcttttg gatttcactc
    22861 tattctgaaa aacttgtgta tatttactga agctagcaag tcttacctgt aaatttaatg
    22921 aaagcaacac aaaatccgag aggggaatct cggattaatg tcaatttaaa aagatagaga
    22981 gtttttagtt taaataaatt gttttaaaat atcaacaaca tcacttcttt tcttaacctg
    23041 ataagccttg attcctaatt ttggggctac gattatattg tcctcaatat cgtctagaaa
    23101 gacacaattt ctaggttata actggtattt atcgatagtt actcatatat atcagtccac
    23161 ctccatactc accttacaga ttcttttgat aataatatct ttgcctaatg tagagatagt
    23221 cttgcaaaga aaaaacttcc ttgtagccat gtttctgata aaagcccggt gcctggaact
    23281 ggtaagtatt gacaaaggca aaacaacaat ttcgattttt agcttcactt tctgcctgtt
    23341 gcaatagttt tgaaccgatt ccttgccctc gcagttcctc ttttacaaac aaatactcga
    23401 tttctagcca atttccaaaa gtctctgcta tcaaacccgc aaggagattg cccttttcat
    23461 cttcgacata aagattaagt ggctcacttt cagcctcttc tctttttgaa cggttataaa
    23521 cacgaatcag attccctatt tcttgcgatt tatatgattc cttattttcc aatctaaagt
    23581 ataatgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta atttctaaca
    23641 atgtcttaga aatcaaagtg tactatttta acttcaatgc actatacatc taatactcaa
    23701 tgaaaatcaa agaacagact aggaaactag ccgcaggttg ctcaaaacac tgttttgagg
    23761 ttgtagatag aactgacgaa gtcagctcaa aacat
//
LOCUS       DAVMBH010000030        22201 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVMBH010000030 DAVMBH010000000
VERSION     DAVMBH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.030"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            635..1018
                     /locus_tag="VYP30_001360"
     CDS             635..1018
                     /locus_tag="VYP30_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1808349.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1070..1759
                     /locus_tag="VYP30_001361"
     CDS             1070..1759
                     /locus_tag="VYP30_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1808350.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFLSLPSLLDIFVFATFGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1801..2034
                     /locus_tag="VYP30_001362"
     CDS             1801..2034
                     /locus_tag="VYP30_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808351.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2185..2796
                     /locus_tag="VYP30_001363"
     CDS             2185..2796
                     /locus_tag="VYP30_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1808352.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGDFFQNESALIIVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2957..3751
                     /locus_tag="VYP30_001364"
     CDS             2957..3751
                     /locus_tag="VYP30_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1808353.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3748..4383
                     /gene="trmB"
                     /locus_tag="VYP30_001365"
     CDS             3748..4383
                     /gene="trmB"
                     /locus_tag="VYP30_001365"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1808354.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4509..4988
                     /gene="rimP"
                     /locus_tag="VYP30_001366"
     CDS             4509..4988
                     /gene="rimP"
                     /locus_tag="VYP30_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1808355.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            5032..6168
                     /gene="nusA"
                     /locus_tag="VYP30_001367"
     CDS             5032..6168
                     /gene="nusA"
                     /locus_tag="VYP30_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1808356.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6190..6483
                     /locus_tag="VYP30_001368"
     CDS             6190..6483
                     /locus_tag="VYP30_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1808357.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6476..6775
                     /locus_tag="VYP30_001369"
     CDS             6476..6775
                     /locus_tag="VYP30_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1808358.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLAKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6792..9584
                     /gene="infB"
                     /locus_tag="VYP30_001370"
     CDS             6792..9584
                     /gene="infB"
                     /locus_tag="VYP30_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1808359.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9835..10185
                     /gene="rbfA"
                     /locus_tag="VYP30_001371"
     CDS             9835..10185
                     /gene="rbfA"
                     /locus_tag="VYP30_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1808360.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            10464..11243
                     /locus_tag="VYP30_001372"
     CDS             10464..11243
                     /locus_tag="VYP30_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808361.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            11245..11427
                     /locus_tag="VYP30_001373"
     CDS             11245..11427
                     /locus_tag="VYP30_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808362.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            11424..11564
                     /locus_tag="VYP30_001374"
     CDS             11424..11564
                     /locus_tag="VYP30_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808363.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(11769..11846)
                     /locus_tag="VYP30_001375"
                     /pseudo
     CDS             complement(11769..11846)
                     /locus_tag="VYP30_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            11877..12110
                     /locus_tag="VYP30_001376"
     CDS             11877..12110
                     /locus_tag="VYP30_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1808364.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            12110..13444
                     /locus_tag="VYP30_001377"
     CDS             12110..13444
                     /locus_tag="VYP30_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1808365.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWIQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            13454..13708
                     /locus_tag="VYP30_001378"
     CDS             13454..13708
                     /locus_tag="VYP30_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1808366.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            13804..14199
                     /locus_tag="VYP30_001379"
     CDS             13804..14199
                     /locus_tag="VYP30_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1808367.1"
                     /translation="MSKKLNRKKQLRNGLRRSGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            14611..15060
                     /locus_tag="VYP30_001380"
     CDS             14611..15060
                     /locus_tag="VYP30_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV1808368.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGGFIKKARKKDGKN"
     gene            15047..15604
                     /locus_tag="VYP30_001381"
     CDS             15047..15604
                     /locus_tag="VYP30_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808369.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKVTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            15606..16568
                     /locus_tag="VYP30_001382"
     CDS             15606..16568
                     /locus_tag="VYP30_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HEV1808370.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDINFTYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            16580..19231
                     /locus_tag="VYP30_001383"
     CDS             16580..19231
                     /locus_tag="VYP30_001383"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1808371.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAIAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNIMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            19301..20056
                     /locus_tag="VYP30_001384"
     CDS             19301..20056
                     /locus_tag="VYP30_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1808372.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            20337..21140
                     /locus_tag="VYP30_001385"
     CDS             20337..21140
                     /locus_tag="VYP30_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1808373.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(21256..22201)
                     /locus_tag="VYP30_001386"
                     /pseudo
     CDS             complement(21256..22201)
                     /locus_tag="VYP30_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6736 a         4042 c         4918 g         6505 t
ORIGIN      
        1 atgcttactt tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg
       61 atgaaaaatt ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctgct
      121 acattatgtt aaaaatcgct cttgattgat aagttggatt tgttaggaaa ggagtaaata
      181 attatggata agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca
      241 gtagataatt tttttagaga cttaaccccg ttactgttca ttttaaatat tattggcctg
      301 tcttgctttt cagtgctaac atacattaac ataaaagaga tactcttaaa tataagtaaa
      361 tgatgatttg gttagtccta gaaccaatca atttatgttt atcggcttgg cagattttat
      421 gtttgtcatt tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc
      481 ttatataggt gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat
      541 tataaaaagt agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa
      601 ttgttagtga aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat
      661 tttcttgagt agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc
      721 tattgggtgg cttgttcttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa
      781 taaaggggtg gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt
      841 tggaaaaacc ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct
      901 tggtttggat gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt
      961 aatgtatcta ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc
     1021 ttacagcagt agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta
     1081 tcaacttcta ttcaaaataa gtgcagtctt ctcttactta tttttcgtat ttggtctttc
     1141 tcagctgacg cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt
     1201 ctggattcaa aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa
     1261 gacaggccat ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt
     1321 gacagtatta gtggtagtgt tccagatctc ttttaacgtt cagacagcta aacatgttca
     1381 gtcaactgcg gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct
     1441 aggtatttat atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg
     1501 attactgcaa catgctttct ttaagcattc gcgatttggc cttgatttgc ttcttccttc
     1561 cattttgttt gctcttcctc attttttgag tctgcctagt ctgttagata tcttcgtctt
     1621 tgcaacattt ggaatcatct ttgccggttt gacccgctat accaagagta tttatccatc
     1681 ctatgcggtg catgtgatca ataatattgt agcgaccttc ccgtttttgc tcacttttct
     1741 acatagggtc ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc
     1801 atgtataaac acttattttt cctagattcc aaaactttag atcggttgac accctatatt
     1861 ctagtcttgg cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg
     1921 gtggttttta atttcctaaa ttccatgcta gctttaatgg ctatattcat aggggctggc
     1981 tatgtggtcg gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact
     2041 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc
     2101 gaagagtata aaatggtttg ttttggaaag gctagaacta aagaatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tggggatttt
     2281 tttcaaaatg aatctgcatt gattattgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct
     2521 ttgattttga ctacctcagt ttttggcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggcttg
     2701 ttgctgggcc ttgcttataa aaagagccaa aacctatggg tttctactct agtccacatg
     2761 ttttacaaca gttggccact cctatattat ttataaaaat tatgaaaagg taagcagaag
     2821 acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg
     2881 agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt
     2941 tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg
     3001 gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat
     3061 gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg
     3121 gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat
     3181 attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg
     3241 ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga
     3301 tttactacag tcttggcaag aaacggctcc agatgctttg cgtaaaaatc attttatcag
     3361 tgaagtgatg gctgatttgc gtcagactat tccaggattt agagaggacc atgcgaccat
     3421 tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt
     3481 agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg
     3541 ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa
     3601 tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc
     3661 caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca
     3721 tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa
     3781 ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg
     3841 cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc
     3901 tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa
     3961 aaatctgttt tgagctacgc tttggacaag gtgcttgaag ttggagtgcc taacatcaag
     4021 ctcttgtggg tagatggttc tgacttgact gactactttg aagacggtga gattgatcgc
     4081 ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg tcgtttgacc
     4141 tacaagacct ttttggacac cttcaaacgt atcttgcctg aaaatggaga aattcatttc
     4201 aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca atatggcatg
     4261 aaactcaatg gtgtctggct agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca
     4321 gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga ggcagaattt
     4381 taagagatag cctaaaatta ggctgtacaa gtgcttttgc tttacataag ttggcaaacg
     4441 tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg cctcttgctt
     4501 atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt gtagaacctg
     4561 tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc agtgacatga
     4621 ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg gcagacttga
     4681 cagaaattat cagtcctgtc ctagacacca tcaagccaga tcccttccca gaacaatatt
     4741 tcctagaaat taccagtcca ggcttggaac gtcctttgaa aaccaaggat gccgtcgctg
     4801 gagcggttgg aaaatacatc catgtcggac tctaccaagc catcgataag caaaaggtct
     4861 ttgaaggaac tttgttggcc ttcgaagagg acgagttgac tatggaatat atggacaaga
     4921 cgcgtaagaa aaccgtccga attccataca gtttagtatc aaaagcacgt ttagcagtta
     4981 aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa
     5041 gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa agaagatatc
     5101 atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg tcagtcagac
     5161 agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa
     5221 gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc tcttgccatt
     5281 aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc tgagtttggt
     5341 cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt
     5401 gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg tacagtagaa
     5461 cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca attgtcaaaa
     5521 caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt ttatgtttac
     5581 aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagcca tccagaaatg
     5641 atcaaacgtt tgatggagca agaaattcca gaagtttatg atggaactgt tgaaatcatg
     5701 agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca caatccaaac
     5761 gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa gattactagc
     5821 aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat
     5881 atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc catcgctcct
     5941 gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt
     6001 ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg cttggcggct
     6061 cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc catggaagac
     6121 gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa gctgctagag
     6181 gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg
     6241 attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt ctttattgat
     6301 cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc agaagcccta
     6361 gaggcgaaaa agaagaaggt ctttaaccgc agctttagca tggaagtgga agaaagcttt
     6421 tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa
     6481 taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca tcatatcggg
     6541 tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct ttctagctca
     6601 tgatgctgga cccaatctgg ccaagaagat tcaagataaa agtcattatt atcaagtaga
     6661 aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat cgagaaaggt
     6721 tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg aatagaagag
     6781 gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa
     6841 gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagc cactcatcaa
     6901 gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca gctgctccga
     6961 aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaaacc gaaaaatctg
     7021 agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca gttgctccga
     7081 aaacagaaaa agtagcagcg aaaccgcaaa gccgtaattt caaggctgag cgtgaagccc
     7141 gtgctaaaga gcaggcagaa cgacgcaagc aaaataaggg caataaccgt gaccaacaac
     7201 aaaacggaaa ccgtcagaaa aacgatggcc gtaatggtgg aaaacaaggt caaagcaacc
     7261 gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa aaacgtagaa
     7321 atgagcgccg tcagcaagag gacaaacgtt caaatcaagc ggctccacgt attgacttta
     7381 aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg
     7441 aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac aaacgcaagg
     7501 aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag caagttcaag
     7561 cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac
     7621 aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt cctagaaaac
     7681 aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt aactggaata
     7741 acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact ccaaaacctg
     7801 ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat ggtatgaccg
     7861 ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag aaacttttca
     7921 tgatgggtgt catggccaca caaaaccaat ccttagatgg ggaaacaatt gaactcctca
     7981 tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct gacatcgaac
     8041 gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt ccaccagttg
     8101 ttactatcat gggacatgtt gaccacggta aaacaaccct tttggatact cttcgtaact
     8161 cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc taccaaatcg
     8221 tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc tttacatcaa
     8281 tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg gcagatgacg
     8341 gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac gttccaatca
     8401 tcgtagccat taacaagatt gataaaccag gtgctaaccc agaacgcgtt atcggtgaat
     8461 tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt gttgaaatct
     8521 cagctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt gtagctgaaa
     8581 tccaagaact caaggcagac ccaacagtgc gtgcaatcgg tacggttatc gaagcgcgct
     8641 tggataaagg aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc
     8701 aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc aacgaccttg
     8761 gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt ttgaacgaag
     8821 caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg cgtgcagcag
     8881 gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa cgtgttagcc
     8941 ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat gttatcatca
     9001 aggctgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag attgacgtgg
     9061 aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa tcagacgtga
     9121 cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct acaccacaag
     9181 ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt atctacaagg
     9241 ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt gaagaaaaag
     9301 ttattggtga agcggttatc cgtgaaacct tcaaggtgtc taaagtggga actatcggtg
     9361 gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt atccgtgatg
     9421 gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagac gacgttaagg
     9481 aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat attaagatgg
     9541 atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt ttgctccttt
     9601 cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt gagcctaggg
     9661 tctcaaaaat cccctgtgat gggactgata aatcagttcc atcactttca ccacggcgaa
     9721 agaagcagat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc aagaagttta
     9781 aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa tatcatggca
     9841 aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg
     9901 caaaagaaag tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt tcagatgttg
     9961 ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc ttcggataac
    10021 caaaaagccc aaatcgggct tgaaaaagca actggtacca tcaaacgtga acttggtcgc
    10081 aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc catcgagtat
    10141 ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag aggggttgcc
    10201 cctctttttt ggtggaggaa aataggttga atttgaaatg gaaaaatatt cttttaaaat
    10261 atattgaaac tagaatagta cgcctctact tctaaaacat tgttagaaat cgatttgact
    10321 gtcctgatcg atttgtcctg ttcttgtttc attttactat aaaaaagggg ttctgtattt
    10381 tttaatgtta tctaattaga aaatgctttt tttgtaggaa atataatatg ataaggtgta
    10441 aaaaagaaat aaggagtttg tatatggctg aacaagactt agctatgcaa gtattacaac
    10501 aagtggtaaa actaccagtt gttaaggttg atcgttcgaa atttttagtg gataagtttt
    10561 ccaaagaatt gggtccacag gacattccta ccttattgga acaaggtcca acgtctctct
    10621 tatctcaaga aatcttagat cgagtggcta atgcctgtat tagggataat gttttattag
    10681 cgagtgggac ttctgttttg gcaggattac ctggagggct tgctatggca attaccattc
    10741 cagctgatgt ggctcaattt tatggtttct ctctgaaatt ggcccaagaa ttaggttata
    10801 tttatggtta tgaggatctt tgggcttcac gcgatgagtt gagtgaagat gctcaaaata
    10861 cccttttgct ttatctaggc gtcatgttgg gggtgaatgg aactgctgct ttgctacgtg
    10921 ctggtggtat aacaattgcc aaacaggtaa tgaaaacagt acctaataaa gctttaacaa
    10981 agacgctttg gtatcctatt ttgaaaaaag tcttaagaat atttggtgtg aatcttacca
    11041 agggagggct ggccaaagga atggggaaat ttattcctat cttgggtggt atcatttcag
    11101 gtggtttaac ctttgcaact atgaaaccga tgggtgaaag cttgcagaaa gaattgtcca
    11161 agctagttaa ctatagtgaa gttcaatatc aagaagatgt tgaaacaatc cgaaaagagg
    11221 ctgaaatcat cgaaggagag taatatggga ctcataaaaa ctctagctaa aatttatggt
    11281 aattactttt tgaccgtgca aggtgtaaaa gtaatgaaaa cgataaagaa agatgataat
    11341 gccgttgtcg gtctggggaa actttttatt gccgacaagt taatggatac ggctcggtgg
    11401 ctcattaagc cagaggagag agaatgaaat ttttctgggg acttcttgcc attattttta
    11461 tcaaaccgat tattgggatt gtgaaattct tttggatgat catttctttt gcagttcaat
    11521 tgctgtttta caagatattg gattggttct ttaaacttat ctagatggta atccaagtcg
    11581 cagaaaacta gcaggaactc cactgctagt tttttaatct ctctccatat ggtataatat
    11641 aagcagtaaa atcattttat actcttcgaa aatctcttca aaccacgtca gcttcacctt
    11701 gcagtatata tgttactgac ttcgtcagtt ctatccacaa cctcaaaacg gtgttttgag
    11761 ctgacttcgt cagttctatc tacaacctca aaacactgtt ttgagcaacc tgcggctagc
    11821 ttcctagttt gctctttgat tttcattgag tattagaaga tacaatagag gtcgtcatgg
    11881 acaatatcat cgatgtgtca attcctgttg cagaagtggt ggacaagcat ccagaagtct
    11941 tggaaattct agtggagttg ggttttaaac cccttgccaa tcccttaatg cgcaatacag
    12001 ttggtcgtaa agtatcactt aaacagggtt ctaagctagc aggaactcct atggacaaga
    12061 ttgtacgcac actggaagcg aatggctacg aagtgattgg attagactaa tgacagatga
    12121 acggattcat atcctacggg atattttgtt agaattgcac aatggcgcct ctcctgagtc
    12181 ggttcaagat cgctttgatg cgacctttac gggcgtgtca gccatcgaga tttcccttat
    12241 ggagcacgag ctgatgaact cggattcggg cgtcactttt gaagatgtta tggaactctg
    12301 tgatgtccat gccaatcttt ttaaaaatgc tatcaaaggt gtcgaagttt tagataccga
    12361 acaccctggg cacccagttc gtgtctttaa ggaagaaaat ttggccctcc gtgcagcttt
    12421 gattcgcatt cgtagattgt tagataccta tgagttgatg gaagacgagg aaatgctggc
    12481 ggagatgcgc aagggcttgg tgcgtcagat gggacttgtg gggcaatttg acatccatta
    12541 ccaacgtaaa gaagaactct tctttcctat catggagcgc tatggacacg attcacctcc
    12601 caaagttatg tggggagtgg atgatcagat tagggaactc tttcaaacag ctctaacgac
    12661 agccaagtca ctaccagaag tgtcaattag cagtgtaaag gaagcttttg aagcttttgc
    12721 gacagagttt gaaagtatga ttttcaagga agagtccatc ctcctcatga ttctccttga
    12781 gtcttttact caggatgact ggattcagat tgcggaggag agcgatgcct atggctatgc
    12841 catcatccgt ccgtcagaga aatgggtgcc agaacgacag agctttattg aggaaaagat
    12901 tgcagaggag cctgtacagc tagatacggc agaaggtcaa gttcaacaag tcatagatac
    12961 gccagaaggc cattttacca ttacctttac ccctaaggaa aaggaagctg tgctggaccg
    13021 ccatagtcaa caggcttttg gtaatggcta tctttcagtc gagcaggcca atctcatcct
    13081 caatcatctc cctatggaga ttacctttgt caataaagaa gatattttcc agtattacaa
    13141 tgacaatacg ccagctgatg agatgatttt caaacgaacg ccgtcccaag tcgggcgcaa
    13201 tgtcgaactc tgtcatccgc ctaagtattt ggacaaggtc aaggctatca tgaagggact
    13261 tcgtgagggg accaaggaca agtatgaaat gtggttcaag tctgagtcgc gaggcaagtt
    13321 tgtccacatc acctatgctg cagtacacga tgaagacgga gaattccaag gagtgttgga
    13381 gtatgttcag gatatccagc cctaccgtga gattgatacg gactatttcc gtggattaga
    13441 ataaggagaa aaaatgagtt acgaacaaga atttatgaag gaatttgaag cttgggtcaa
    13501 tacccaaatc atgattaacg atatggcgca caaggaaagt caaaaagttt acgaagaaga
    13561 ccaggacgag cgtgccaaag atgccatgat tcgctacgag agtcgcttgg atgcttatca
    13621 gttcttgctt ggtaagtttg aaaacttcaa agcaggcaag ggattccatg atttgccaga
    13681 aggcttgttt ggtgagcgaa attattaaac gagaaagatt cttgattttt cactaaaatc
    13741 ttgatagaat gtttatgtta aatccttgtc agagcaggga ttttttattg aaaggatttt
    13801 atcatgtcaa agaaactcaa tcgtaaaaaa caattacgaa atggcctccg tcgctcaggt
    13861 gccttttcaa gtactgtgac taaggttgta gatgagacaa aaaaagtcgt gaagcgtgca
    13921 gaacagtcag caagcgcagc tggtaaggct gtttctaaaa aagttgaaca agcagtagaa
    13981 gctaccaaag agcaagctca aaaagtagct aattctgtag aagattttgc agcaaacttg
    14041 ggtggacttc cacttgatcg tgccaagact ttctatgatg aaggaatcaa gtctgcttca
    14101 gatttcaaaa actggactga aaaagaactc cttgacttga aaggaatcgg cccagctacc
    14161 atcaagaaat tgaaagaaaa tggcatcaag ttcaagtaat ttttcttgag ccttgcattt
    14221 ccgagaaaaa cttgctacaa tagagccatt agaggtgttt tgaatcccac attttacaga
    14281 aagtggcggc gctgagaagt ccacaaatgt gtcaaaactg gttgctaatg actgaaaaaa
    14341 tgaaatattt ctgtcttttt attttaaaga ctaaagatgc gggcttggcc cgaaattggg
    14401 tggtaccgcg gataaacaca ttcgtccctg tcatgtagat ggcagggctt ttcttttgtg
    14461 tcttagtcaa aggaggttgt tataaaacaa tcatttaaaa ctaataaact atattatggt
    14521 tttcctgttt ttattttagg atatcaagat tagaattttg gctataacat cacgacctgt
    14581 agttcctctt atagtctagg agattgggtt gtgattggag tcgttgcgag agagaatgcc
    14641 gcagagcaga tcaaacagta tcaaaaattt actgtgaata tttctgatga aacttctatg
    14701 cttgcgatgg agcaggctgg ttttatcagt catcaggaga aattggaacg tttgggagtg
    14761 cattatgaaa tttctgaacg aactcagatt cctattttag acgcctgtcc acttgtttta
    14821 gattgtcggg tagataggat tgttgaggaa gacggtattt gccacatctt tgccaagatt
    14881 cttgagcgac ttgttgcccc agaactcctg gatgaaaagg gacattttaa aaatcaactg
    14941 tttgccccaa cctatttcat gggagatgga tatcagcgcg tttatcgcta tctggataag
    15001 cgtgtagata tgaagggcgg tttcatcaaa aaagcgagga agaaggatgg caagaactga
    15061 gctgccagat aaaatcgaaa cagaacgtct cgttttacga gtccgtactg tggcggatgc
    15121 tgaggatatc tttgactatg ctagtttgcc agaggtcgcc tatccagcag gttttcctcc
    15181 agtcaagacc ttggaagatg agatttatta tctggagcac attcttccgg agcgtaatca
    15241 aaaggaaaat ctcccagcag gctacgggat tgtcgtcaaa gtaacggata agatcgttgg
    15301 ctctgtcgat ttcaaccatc gccatgaaga tgatgtgctg gaaatcggct ataccttaca
    15361 cccagactat tgggggcgag gttatgtgcc agaagctgcg cgtgccttga ttgacttagc
    15421 ctttaaagat ttgggtcttc acaagattga actaacttgc tttggatata accttcaaag
    15481 taaacgagtc gcggaaaagc ttggctttac cctcgaagct cgcataagag accgaaagga
    15541 tgttcaagga aaccgctgtg acagtctgat atatggcttg ctgaagagcg agtgggagga
    15601 ataagatgag cgatgtaaaa gaggaagtaa gctctctatc tgagaagcag ttacgccaaa
    15661 ttgatgttga gtatgctgaa ttaaatgata gtgatattat cgagcgatta gcttatttag
    15721 aaattaacaa caatgaaaaa cgtattgtca tctctgatat tgaaccaacc aaggaaataa
    15781 tgtcagtctc ggaccaaatt tttgagattc aaaagaattt tcaaaaaatc aagaatatgt
    15841 tcgaattgtt tatttcagat gtctcggatt ttttaagtat taaaaataaa cttgagtcaa
    15901 aggaattaga aattgaagag gcagatgtaa atcgtttcat gattcattta ttatccagtg
    15961 gaaaattgtt tgtcgatttt aacgaaaacc aaattaaaca aaaatattcc aaagatagtg
    16021 aggagtttga ttgtatacat ggttttgcaa gctatcagta tgatatcaat tttacttatc
    16081 gattttgcca ttctttgaga aattattcgc aacatactga cttaccaata aatgaggtaa
    16141 aagctgttag cccagatgat gagactgtta taatagattt ctatattgat ttagattatc
    16201 ttttaaattc caactttaaa tggaaaaaat tgaaagggga gttgataaaa ctaaaccaag
    16261 aaacatctaa gattgacgct atagctctag tgaaagaata ctttaatgct cttacagagc
    16321 tctatggtaa ttataataag ttgtttttaa agttaaacca taatacatta gtagatatta
    16381 aatcaaagtt ggaatcatta aaattgaaac actctaggta ttatatttca aagataagca
    16441 agtatgatct taaatataat cctggaaatt atactatgtc accacttgca gcatttgctg
    16501 aaattgaaga gatttatatt gaactttcaa aaattggttt ggttaaaatt gtcaataaaa
    16561 gtaattaagg agaacacaca tgtctaaaga actttcatct aaatacaatc cagccgaggt
    16621 tgaggctggt cgttaccaaa aatggcttga tgctgatgtt ttcaagcctt caggcgatca
    16681 aaaggctaag ccttattcaa tcgttattcc accaccaaac gttacaggta aacttcacct
    16741 tggtcacgct tgggatacaa ctttgcaaga tattatcatc cgtcaaaaac gcatgcaagg
    16801 ttttgatacc ctttggcttc ctgggatgga ccacgcaggg attgccactc aggctaaggt
    16861 tgaggagcgc ttgcgtggtg agggcatttc ccgctatgac cttggtcgtg agtctttctt
    16921 gacgaaagtc tgggaatgga aagacgaata tgccactacc atcaaggaac aatggggcaa
    16981 gatggggctc tctgtagact attctcgtga gcgtttcact cttgacgaag gtttgtcaaa
    17041 agctgttcgt aaggtctttg tggaccttta caagaaaggc tggatctacc gtggtgagtt
    17101 tatcatcaac tgggacccag cagctcgcac agccctttct gatattgagg tgattcacaa
    17161 ggatgtggaa ggtgccttct accacatgaa ttacatgctg gaagatggtt cacgcgccct
    17221 tgaagttgct acaactcgtc ctgagactat gtttggggac gttgcgattg cggttaatcc
    17281 agaagacccg cgctacaagg acttgattgg taaaaacgtc atccttccaa tcgctaataa
    17341 actcatccca atagttggag atgagcacgc agatcctgag tttggtactg gtgtcgtgaa
    17401 aatcacacct gcccacgatc caaatgactt cttggttggc caacgtcata acttgccaca
    17461 agtcaacatc atgaacgacg acggaactat gaacgagctt gcctttgaat tttcaggcat
    17521 ggatcgtttt gaagctcgta aggcagtcgt tgctaagttg gaagaaatcg gtgcccttgt
    17581 caaaatcgaa aaacgtgtcc acagtgttgg tcactcagaa cgtacaggtg tcgtagttga
    17641 gccacgcttg tctactcaat ggttcgtcaa gatggaccaa ttggctaaga acgccattgc
    17701 caaccaagac acagaggaca aggtcgaatt ctacccacct cgtttcaacg ataccttcct
    17761 tcaatggatg gaaaatgtcc acgactgggt tatctctcgt cagctctggt ggggtcacca
    17821 aatccctgct tggtacaatg ctgatggtga aatgtatgtc ggcgaagaag ctccagaagg
    17881 tgacggatgg actcaggacg aagacgtctt ggatacttgg ttcagttctg ccctctggcc
    17941 attttcaacc atgggctggc ctgaagtcga ctcagaagac tttaaacgtt atttcccaac
    18001 ttcaaccttg gtaacaggtt acgacatcat cttcttctgg gtgtctcgta tgatcttcca
    18061 gtcattggaa ttcacaggcc gtcaaccatt ccaaaacgtc cttatccacg gtctcattcg
    18121 tgacgagcaa ggacgcaaga tgtctaagtc tctcggtaac gggattgacc caatggatgt
    18181 tatcgagaaa tacggtgccg atgcccttcg atggttcctt tcaaacggtt ctgcgccagg
    18241 acaagacgtg cgtttctctt atgagaaaat ggatgcttca tggaacttta ttaacaagat
    18301 ttggaacatt tctcgctata tcctcatgaa caatggaggt ttgacgctgg atgtggcgca
    18361 tgacaatgtc acaaaagttg caacaggtga ggctggtaat gtgacggacc gctggattct
    18421 ccacaatctc aacgaaacca ttgcaaaagt tactgaaaac tttgataagt tcgagtttgg
    18481 tgtggctggt catatccttt acaacttcat ttgggaagaa tttgccaact ggtatgttga
    18541 gttgaccaag gaagttcttt acagcgacaa tgaagacgat aaggtaatta ctcgatctgt
    18601 tctcctctat acgctggata aaatccttcg tctccttcac tcaataatgc cgttcgtgac
    18661 agaagaaatc tttggtcagt acgctgaagg ctctatcgtg acagcagcat acccaactgt
    18721 caacccagcc tttgaggacc ttgctgccca cactggtgtg gaaagtctca aagacttgat
    18781 ccgtgccgtt cgtaatgcgc gtgcggaagt aaatgtagca ccaagcaaac ctatcaccat
    18841 ccttgttaag actagcgata gtgacttgga agccttcttt aacagcaatg tcaactacat
    18901 caaacgcttt acaaatccag aacacttgga aatcgcatca accatccctg cacctgaact
    18961 ggctatgtca agcgttatta caggagccga aatcttcttg ccactggtag acctcttgaa
    19021 tgtcgaagaa gaattggcac gtctggaaaa agaacttgcc aaatggcaga aagaactcga
    19081 catggttggc aaaaaactca gcaacgaacg cttcgtcgcc aacgctaaac cagaagttgt
    19141 ccaaaaagaa aaagacaaac aagccgacta ccaagccaag tatgatgtga ccgtagcacg
    19201 tattgatgag atgaagaagt tggtgaaata aacacagaaa cacggtgatg agccgtgttt
    19261 tttggtataa tgaaatcaat atctattgat ggagaaagtg atgtccaaac accctcatta
    19321 tgaattgtta aatttaattg gctacggtct tgccaagttt gacaagcttt ttataaaaga
    19381 atttcaatgc tctagcaagt cggagtttta tcgctatgtg gtttctctgg gaattgctga
    19441 aacaactgga gttgtaaaaa atagaatgga tttatttgat ccttattttg acaataatcg
    19501 aaaaggttgg tggcagaaag ctgaagttta tcgttttcgt aaagatttaa ttgatatgat
    19561 gtttggaaat gaagatgttc atagttatgc tgaaatagtt aaaatgttac ttgccagtga
    19621 agggaagaaa acaggcataa ccatcgttga aaaaccaata gttcgaacta aattcaaacg
    19681 tctacaggaa acgggaatgg aggctgagaa ttattttatc cttcattttg ataaagaaga
    19741 aaaattccaa ggtggacagt taaccgatgc ccgtctttat ggtgatggat atgactttca
    19801 ggtagatgtc caagagtatt cttaccttgc cgaagtaaaa ggtatccgaa aatctaaggg
    19861 gcgtgtgcgt ttaactgcaa aagaatttga aaaagtcaag gagtttcaat cggattttat
    19921 tttatccttg gtcacaaatc tagatgatat tccaaagtta gtgttaatcg ataatccttt
    19981 aaaacatttt gagtttaaaa agaatattat caaaaatgaa atcattgaat atagaagcgt
    20041 agaggatttg tattagttcc cccttaactt ttccagttga aggaacgaga agtcttgaca
    20101 ggtcaacgac ttaatgaact ggaaatcaac ggtattcgtt tgactaagtt ttaagatggc
    20161 gaaatcggta ttgaatttat cagtagtgct gattataact cttttattat ttacatgaag
    20221 tatatatata tatatatcat agaacctatt gtgaggactt tttatagttt aagccagttt
    20281 ccaaccaatt tcgtgattta ctggtaatga agaaaaacaa ttgaaaggat atttctatgc
    20341 aaccaactta caacattgac aatccaaact tgtcttatga agcgaagcgt gatttatggc
    20401 ggataggttt tggtctgcag aaagttgaca atctagtgcc atcagcgtat atggaatctt
    20461 tggctgagaa acagtcccgg ggagaactga cttatgagca ggtttatgag gatgcaacgg
    20521 cttatcacca tactattgat gcaagtacgg aagaggcaga cttggtttct ctacgtattg
    20581 tagaactatt gtctcgaaga ggctttagct ttagtcctgc gaccttactt gctattcata
    20641 aggagttgtt tcaagatata tttgaaccct ctattccggt ggggcaattt cgtcagacca
    20701 atatcacaaa gaatgaacct gttttgaatg gtgaaagtgt tgtgtactct gattactcca
    20761 tgattcaaat gaccttagat tatgatttta atcaggaaaa acaagttgca tatgcgacac
    20821 taactcaggc ggatgtggtt aaacaaatcc agcattttat ttcaggaatc tggcagattc
    20881 atccatttcg cgaaggaaac actcggacag taacggtctt tttgattcag tatcttcgtg
    20941 agtttggttt tgatattgat aatacaccat ttcagcaaca ttccaaatat tttcgtgatg
    21001 ccttggtatt agataatgca aagattttac agcgacgttc tgagttttta acagcttttt
    21061 ttgaaaatct cttgctcggt ggtcaaaatg atttgtcttc agaaaaaatg tatctagatt
    21121 tagacctcga tttttcataa tccaaatact gagtaaacat tgaattttag gcaaaaatga
    21181 agtaaatatt ctcacaagaa aacgtatatc atcaaagttt taggtgtact gaccccaaaa
    21241 agttagacaa ataatttatc cgaaggattt agttctgtat tgcacaaggc taagtccttt
    21301 tagttttacc ttaattcgtt tattgttgta gtaatcaata tagtctacaa tagcttgttc
    21361 caattgatta agtgatttaa atgttttctc atagccataa atttcagaat cccaaagaag
    21421 gactccatca taccgttgtc ttggctgttt cccttgcgtg acatggatgc ttgaattccc
    21481 ttactctcta agaaccgatg ataagaatcg tgttgatatt gccagccttg gtcactatgg
    21541 agaatcgtat tctcatagta tttctctgta aaggcctgtt ctaacatact cttcacttgt
    21601 tctaagttgg gtgaagttga aagattatag gcgataattt cgctgttaaa gccatctaaa
    21661 actggtgata agtaaagctt ttgagtactt gctggaatgg caaattctgt cacatctgtg
    21721 tagcactttt ccattgtttt agagccttca aattggcctt gaatgagatt ctctgccttc
    21781 ttaccaacgt ctcctttatt ttcgtttctg tcacatttta gcttgtaaat tgagtacttt
    21841 catcaagtct tgaactcttt tatgatttac cagataagca cgatttctta gttctaaata
    21901 aattcgacga taagcataat ttcccttgtg ttcgataaag atggattgaa tttcagcttt
    21961 aagctcttgg tccttatctg gtttatctag ctgtttcaag tgatagtagt aggtcgaacg
    22021 agctagttta atggctttta gaagaagatc taacgaaaac tcagtcatta attcttgaac
    22081 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
    22141 aggatggcat tctccgatct caggtactct ctctcttgtt ttctcaacaa tagtataccc
    22201 g
//
LOCUS       DAVMBH010000031        22093 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVMBH010000031 DAVMBH010000000
VERSION     DAVMBH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.031"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..1030
                     /locus_tag="VYP30_001387"
     CDS             <1..1030
                     /locus_tag="VYP30_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808374.1"
                     /translation="KNDKKIKFLNYMFKSNYHFVNMNPISFLENIEESSMQSVIVSSP
                     ESEKYEWQLAYLTQLENVKNEDLQTLKSILEANSLPCYFTILNFERLILKDPSLKELL
                     IQKAGNTNFVISDFIREEEVPKLINLIGVKELKFWYLINLENCQNHSYNLFQKLGEKD
                     VDFSVEVLKKIDELRIGHSNLGYMVLHSISEFRDKKEIYKKFIRFAINRPYYYYNNMI
                     DDIIKNDSQIILEILEETNNEQSAIRLVNLGVEFLENNNQKLILFNLLRAKGFGKKSF
                     QEIHFTPYSHFYTDSHVPVLELEKELLERIKKIFETGIDYINLLLYLNKLIDCKRKAI
                     ERELEKEF"
     gene            complement(1318..2664)
                     /gene="gdhA"
                     /locus_tag="VYP30_001388"
     CDS             complement(1318..2664)
                     /gene="gdhA"
                     /locus_tag="VYP30_001388"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1808375.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            3201..3657
                     /locus_tag="VYP30_001389"
                     /pseudo
     CDS             3201..3657
                     /locus_tag="VYP30_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            3660..4673
                     /gene="efeB"
                     /locus_tag="VYP30_001390"
                     /pseudo
     CDS             3660..4673
                     /gene="efeB"
                     /locus_tag="VYP30_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            4648..5226
                     /locus_tag="VYP30_001391"
     CDS             4648..5226
                     /locus_tag="VYP30_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1808376.1"
                     /translation="MVRNYWKAKSWLLVLALSFLILSPAGAQESLSFFFVKITDASKT
                     VKNGGQTETQKLVTKMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSTAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5283..5567)
                     /locus_tag="VYP30_001392"
     CDS             complement(5283..5567)
                     /locus_tag="VYP30_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1808377.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(5621..6556)
                     /locus_tag="VYP30_001393"
     CDS             complement(5621..6556)
                     /locus_tag="VYP30_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1808378.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            6660..7103
                     /locus_tag="VYP30_001394"
     CDS             6660..7103
                     /locus_tag="VYP30_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1808379.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            7219..7485
                     /locus_tag="VYP30_001395"
     CDS             7219..7485
                     /locus_tag="VYP30_001395"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1808380.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            7482..7856
                     /gene="crcB"
                     /locus_tag="VYP30_001396"
     CDS             7482..7856
                     /gene="crcB"
                     /locus_tag="VYP30_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1808381.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            7850..8179
                     /gene="crcB"
                     /locus_tag="VYP30_001397"
     CDS             7850..8179
                     /gene="crcB"
                     /locus_tag="VYP30_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1808382.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            8298..8645
                     /gene="rplS"
                     /locus_tag="VYP30_001398"
     CDS             8298..8645
                     /gene="rplS"
                     /locus_tag="VYP30_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1808383.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            8687..8758
                     /locus_tag="VYP30_001399"
     tRNA            8687..8758
                     /locus_tag="VYP30_001399"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8720..8722,aa:Arg,seq:cct)
     gene            complement(8813..9619)
                     /gene="yidA"
                     /locus_tag="VYP30_001400"
     CDS             complement(8813..9619)
                     /gene="yidA"
                     /locus_tag="VYP30_001400"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1808384.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELFTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(9632..10936)
                     /locus_tag="VYP30_001401"
     CDS             complement(9632..10936)
                     /locus_tag="VYP30_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1808385.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQENQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            11008..11385
                     /locus_tag="VYP30_001402"
     CDS             11008..11385
                     /locus_tag="VYP30_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1808386.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            11607..13757
                     /locus_tag="VYP30_001403"
     CDS             11607..13757
                     /locus_tag="VYP30_001403"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HEV1808387.1"
                     /translation="MLKTQEIADKYGITRQTLNNWMQKGIISQPRKNNRSAYEWEEEN
                     EKEIVRVISEEIPAKYYVSNKETLKIGNRRYLGSKQKMLDFILKTVSENIGSIDSVAD
                     IFGGTGVVADLFRKQNKKVIVNDILYSNFISFQTWFSNEDVDIHKVSHIIDELNNLSP
                     KKGYVSKNFGGAYFSEENAGKIDSIREEIEKYKSGNQREYFMLLTSLLYAMDKVANTV
                     GHYDAYRKKMDYCKEIYLRVPEYNENNQNEIYNKDANKLVKEIYADLVYIDTPYNSRG
                     YENAYHVLENIAEWKKPDVEGVAKKAVNRSEKGSDYTKSKAPQAFEDLILNINAKYIL
                     VSYNNMNKKGNSRSNAKISNEEIIKILSKRGKVQVFETDFSPFTTGKSKIENHKELLY
                     LCIISPEKKKEKKLIKSALNYTGGKYKLLPQLLPLFPESYNNFIDLFSGGATVAVNLA
                     NINKSKTKKYIINDISEEVIDFYKYLESQKDVTVFLDKVEKAIEFYKLSNTQKYSYAH
                     YGVNSSTGLGSYNKEAFLKLRQDYNKKNYNKFDKEVLFYLLIVFGFNNQIRFNNKGEY
                     NLPVGKRDFNANMKSKLITFIQGLQNYNFVIQSCDFRKTMNQVNKGDFVYTDPPYRIT
                     TAAYNENGAWTLKDDLDLFKYLDSINDKGAYFALSNVVIHNNKENKELMKWASKYNLH
                     VLDYHYNNSNYQSKAKMSNTVEVLITNYNSKGDI"
     gene            13754..15766
                     /locus_tag="VYP30_001404"
     CDS             13754..15766
                     /locus_tag="VYP30_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HEV1808388.1"
                     /translation="MRLKESTSIFNMGDTSIRVKEVVPIYKQILKTLQKHNQSNQKWN
                     NESQASFYSSVLSDFAKAETEDGINLFGNLKRNEITGLDKRGRTLTNALVKIGFINYD
                     RKLSQVGLNYISETEQAFDKLEELFGLTIDNLVYFRQLLKLRIYDSNSDKYFYNFRFA
                     LAFLNRYSKVPVRDFLWIVESIKPNFSEEKIKVIIDNYQSVYDNNKTFEQYRDEEFAN
                     HILIPERVDEARKMFSIKNFSDENFKKLFPNRKNSNKSLEYKSFVLSIINFTEEKTER
                     SFEEMMSLSKQDAIKKAFGDGKAVFKYKNKDSIQDFITKNSDNPLLSGQYLDIYYAFT
                     WSKHNDLIKEYSDMCKRIFSLSGVISFNQGIVSLGRPWIFPKLFSLLNGNFKLSGEAS
                     YEEYENDIKSSFYQDICISDILELSYTQVLEIQNQIAEEFGIADISNIKQFVADKQER
                     EFREFVEQEFGITKVSEVLSFISQRNDKKVQELVTDNALVPTIFEYILAIAWYYISDK
                     KFQLRKSMQLTFSADNLPLSHAGGNKGDIEIEYSDKMLLLEATLMDKSTQKRGELEPV
                     IRHSVNLALSTNKPLQTIFVANEVDDNVVNIFRATSFIQLNGTLTKGSVKGLNIFALT
                     IPEIINILDRKINEQRIFEKLDDFSTIEPYRIENGWREEIVSEILA"
     gene            15834..18395
                     /locus_tag="VYP30_001405"
     CDS             15834..18395
                     /locus_tag="VYP30_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HEV1808389.1"
                     /translation="MIQRGSEFRKWDLHIHSPYTVLNNQFDKLPDGSPDVEKFIQKIK
                     DEGISAVGLTNYFRFSDDDFKLKDRLNEEGIATFLNLEVRLSNINKSDELFDYHVVFG
                     NEVQDDIVKNLLGHLKANIGDDEKSFNRLSKTEIEDKAHIPFKDLLKVLNSDRELNGR
                     FLTGFLSRGHGSATSDSDSKNKAVYEDICINSDFLIHSSNEVNITKDREFWLDKSPHI
                     RPLLQSSDSHSLEQIGSKYSWVKADLTFDGLEQIKYEPEYRISVEKEKPTLKKDELVI
                     DKILYNGQDIYLSENLNTIIGGRSTGKSTLLNSIAKKLGRELNGDSYYFENMDDFQII
                     WKDQQEDNSRQIEYIPQEYMFALARDNKKLKDLVGSIIQSKEMNSELKKYEQNCATLH
                     LEIRGLLDSYKENQKNIHELIKPEAEKQATQNRIKTYETKKKELLNASEITEQERDLF
                     ENKNKELQLLKTQKEIHESDLRYVSSILPITFEVESLPTTTTPSQDLRVKIGQITARL
                     RDSVRAQQEHEIRIIKLEKESLIKAIENKISDIGNDDIYKKCVEAMKNNSEIARLNSL
                     IKNEVDILAKIEAFEKQRDEFDKVTEEIQKEIISKYKEYSNIRTELLNNFKIEDDNGD
                     NLKISVKFSLIDLEAEFDYINARGRSKQDFIEKMIGSFEEVVDSIFDEDSLAFNGNRD
                     KFSHIEHFFTTNFYEYSFEIEYQGDKFEQMSPGKKAFIVLKLILEFSDSKIPVLIDQP
                     EDSLDNRAIYSELTKYIKKTKKNRQIIIVTHNPNIVVSGDAENIIVANQQSDNSPNQN
                     GKKFDYVNGALENRNNDSTSEFILQKYNIREHVCDILEGGEDAFIKRENKYSING"
     gene            18528..18860
                     /locus_tag="VYP30_001406"
     CDS             18528..18860
                     /locus_tag="VYP30_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1808390.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            18872..20443
                     /gene="ffh"
                     /locus_tag="VYP30_001407"
     CDS             18872..20443
                     /gene="ffh"
                     /locus_tag="VYP30_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1808391.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRLAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(20638..21921)
                     /locus_tag="VYP30_001408"
     CDS             complement(20638..21921)
                     /locus_tag="VYP30_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1808392.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT         7275 a         3552 c         4566 g         6700 t
ORIGIN      
        1 aaaaaatgat aaaaagatta aatttctaaa ttatatgttt aaatcaaact atcattttgt
       61 aaatatgaat ccgattagtt ttttagaaaa tattgaggaa agttcaatgc agtctgttat
      121 tgtttcctct ccagaatcag aaaaatatga atggcaactt gcttatttaa cacaacttga
      181 aaacgttaaa aatgaagatc tacaaacatt aaagagtatt ctagaagcta attctttacc
      241 atgttatttt acaattttaa attttgagag attgattttg aaagatccta gtttaaaaga
      301 gttgttaata caaaaagctg ggaatacaaa ttttgttatt tctgatttta taagagaaga
      361 agaggtgcca aaattaataa atctaattgg agtaaaagag ttgaagtttt ggtatttaat
      421 aaatttagaa aattgtcaga atcacagcta taatcttttt caaaaattag gtgaaaaaga
      481 tgttgatttt tcggtagaag tattgaagaa aattgatgaa ttgagaatag gtcattccaa
      541 tttaggatac atggtattac attctataag tgaatttaga gataagaaag aaatttataa
      601 aaagtttatc cgttttgcaa taaataggcc atattactac tacaataata tgattgatga
      661 tattataaaa aatgacagtc agatcatatt agaaatactg gaggaaacaa ataatgagca
      721 atctgcaatt agattggtca atctaggtgt agaattttta gaaaacaaca atcaaaaact
      781 aatactattt aatcttctca gagctaaagg atttggtaag aagtcattcc aagaaataca
      841 ttttactccc tattcacatt tttatactga tagtcatgtt ccggtgttgg aattagaaaa
      901 agaactccta gaaagaatta aaaagatatt tgaaacgggt atagactaca ttaacttgct
      961 actgtacttg aataaactaa ttgattgcaa gcgaaaagct attgaaagag aattggaaaa
     1021 agagttttaa attttaattt atatttctta ctttttaagg tgccagatat aataaataaa
     1081 atctactgtt ttataacaaa atattaggtt tgagttatga attgtgggaa atgataatct
     1141 atagtaggat agttttattg tcttttcaaa aatagacaat aaatatatta aaaacattag
     1201 cctatataaa gaaaaaggta gaattctata tttttgcata aagggtatta gaatcttaaa
     1261 ttttaggaat tgaaaaaact ggctacccgt ctgggtagtc agtttccgta atttttttta
     1321 taccacgcct tgtgcaatca tagcgtttgc tacattttca aaggcagcaa tgttagctcc
     1381 tgcaaggtag tctttatcaa gaccatatgt ttctgaagtt gttttagctg tgttaaagat
     1441 gttggtcatg atgtctttga gacgtccatc aacttcttca cgagtccatg agaggcgaag
     1501 gctgttttgg ctcatttcaa gggctgaaac ggctacacca ccagcgttgg cagctttggc
     1561 aggtccgtag aagataccat tttctttgta aactttgatg gcatcaaggt tgcttggcat
     1621 gttggcacct tcagatacac agataacgcc ttgagcaacc aaacgtttag ctgcttcacc
     1681 gttgatttcg ttttgagtag cacatggaag cgcaatgtca tagtttccag cgtaagtcca
     1741 tacagaacct tcatgataag tagcagttgc tttctcagct gcatactcag tcaaacgagc
     1801 gcgacgtttt tctttaacat caaccaaaag atcgaagtcg ataccgtttt catcgataac
     1861 atagccgttt gagtcagaaa cagagataac tgttgcacca agttcggttg ctttttgaag
     1921 agcgtattga gcaacgttac cagaacctga aataacgact ttcttaccag caaagctgtt
     1981 accgttagct ttgagcattt cttcagtata gtaaaccaaa ccgtaaccag ttgcttctgg
     2041 acgaatcaag ctaccaccaa atccaagagg tttaccagtc aagacaccag catcaaattg
     2101 gttaagacgt ttgtattgac cgtaaaggta accaatttca cgtccaccaa caccgatatc
     2161 accagcaggt acgtcaagtg atggtccgat gtgtttttgc aattcagtca tgaagctttg
     2221 gcagaagcgc atcacttcag catctgtttt acctttagga tcgaagtctg atccaccttt
     2281 acctccaccg ataggaagtc cagtcaagac atttttaaag atttgttcaa atccgaggaa
     2341 tttcaagatc ccttggttta cagttgggtg gaaacgaagt ccacctttgt atggtccaac
     2401 agctgagttg aattgaacac ggtagccgcg gtttacttga acttttccat cacggtcaac
     2461 ccaaggaaca cggaaagaaa tcacgcgctc aggctcagta atacgtgcca agatattttc
     2521 ttcgatatac tcagggtgtt tttcaaatac aggttccaaa gtgttgaaaa attcttcaac
     2581 agcttggagg aattcagcct cgtgcccgtt acgagctttt acagtttcaa acacgctttg
     2641 gatatattct ttagcagatg tcatatcgtt ctccttttat tgtcatattt tattacataa
     2701 gacattatag cagaattttt tttcactgta aagaaaaaac agaaattttc taaaaattct
     2761 ttcaattcag tttttggttt tttttgaaaa tagataaaaa aacgaacgtt tttcttggaa
     2821 atatctttct caaagacaaa atcttaaagt atggtatgct ataagaaaag aaaatgttta
     2881 gcaattcaga aatcacttgt taatttatcc gtgatatgtt agatttgcta gtaaaattat
     2941 gaccattttg gaggaaagca atatttatac cagactaaaa tcaaaaagca ttatataata
     3001 gtgatatgaa atcaactaaa gaagaaatcc aagccatcaa aacactttta aaagactctc
     3061 gtacagctaa atatcataaa cgccttcaaa tcgttctata gtaaaacgaa acaagaacag
     3121 ggcaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac
     3181 tattctagtt tcaatctact atatttcgtc tgatgggcaa atcttataaa gagattatag
     3241 agcttttaga ctgtaatcaa acaacgattt ggcgaaatgt aaaaaaatat gaggagttcg
     3301 gactcgactc tctccttcaa gaaacacgtg gtggtcgtaa ccatgcatat atgacagttg
     3361 aggaagagaa agcctttctt gcccgtcatt tgaaggctac agaggcagga gaatttgtta
     3421 caattgatgc cttatttcag gcttataaaa aggagttagg tcgttcctac acacgtgatg
     3481 ccttctatca actgttgaag cgccatggtt ggcgaaatat tacaccacgt ccagaacatc
     3541 ctaggaaagc agacgctcaa accattgtcg cgtctaaaaa taaaatctca attcaagaag
     3601 acaagaaagc gctttaaaac cagtagacct tttcataagg ttcgcttgat gtaccaaata
     3661 gtacgcccat gcaaaagaat atctattttg ttgtcttgga cctgcatacg acggatagag
     3721 ataaaattat ccagctattc aaggattgga cggattatag tgccaagttg gtcgaggggg
     3781 aattggttaa aaaagatgga cagaatgctc tctttcctcc gagcgatact ggtgagaaag
     3841 ttgggctcaa tcctcatcgt ttgacgctga cttttggtgt atctgcaagt ttcttgaaaa
     3901 ggatgaactt ggaaaacaag cgccctcgac tgttcaggga tttacctcta tttcctaagg
     3961 agcaattacg tgaaaaatat actggtggag atattgtgat tcatgcttgt gcagatgatg
     4021 agcaaattgc ctttcacgct attcgcaatc tcatccgtaa ggggagaaat gcggtgcccc
     4081 ttcgttggag tcagtctgga tttgcagcta tcggggatcg aatggagact ccgtggaacc
     4141 tctttggttt taaggatgga acagcaaatc caaccaagga gcaagacttt gaccgcgtta
     4201 tctgggctga tagtaaggac tggatggaaa atggttctta tatggcagtt cgtcggattc
     4261 agatgttttt agagacctgg gaccgcacta gtctcgaaga acaagaaaat acctttggtc
     4321 gttacaagga aagcggtgcc ccctttggta agaaaaatga gtttgatgaa gtggatttga
     4381 gtctcttacc tgatgattcg catgtttgtt tggccaaaga agtggataag ccacttttac
     4441 gtcgttctta ttcttactca gatggcattg atgaaaagac tggtcagttt gatacgggat
     4501 tgctcttcat ttctttccag aaggatcctg ataactttgt taaggttcaa actaacctag
     4561 gtgctactga taagatgaat gaatacatca ctcacatagg tagtggactt tttacttgct
     4621 ttggtggtgt ggagaaagga ggctacattg gtcagaaatt attggaaggc taaaagctgg
     4681 ttactagttt tagctttgtc atttttaatt ctttccccag caggtgccca agaaagcttg
     4741 agttttttct ttgtgaaaat cacagatgca tccaaaacgg ttaaaaatgg tggtcagact
     4801 gagacccaga aactcgttac gaagatggca tcagacttcg aaagagtaga aaataaggat
     4861 tctgaggttg gtaagattgt taaggaaaag ttagctctat ctggagatat tactgaagcc
     4921 aaactcaccg aaatttcctc agctctatta gcttttgaaa aagaacaaaa tcctgttgac
     4981 ctagatgcgg aaaaggaaaa attggtaaac cgtctaagtc ctcgttttga aaccttagaa
     5041 caggccattg cctccaaaga tttggaaaaa gtccgagaag cttttaagaa aatgaattcc
     5101 acttggacca tcaatgaaag tgtggttcgt gacaatagta cagctcatta tggacgtgtt
     5161 gaaacagcta tttccttcct gcctagtagc atggaaaccg aacctacaga tgagtctgga
     5221 acatgaaaac agcagttgat ttcaagaaac aaaaaagaac agccgaaact gttctcttat
     5281 cattatttga gaccgtattt tttgttgaaa cgatccacgc gtccatctgc ctgagtgaac
     5341 ttttgacgtc cagtgtagaa tgggtgtgag tctgatgaaa tttccacacg gatcaatggg
     5401 taagtttcgc cttcgaactc aactgtttcg ttagagcgtt ttgttgaacc gctaaggaat
     5461 tggtaaccag tagttgtgtc catgaagaca actgggcgat attctggatg gatatctttt
     5521 ttcattttgc aatatttcct ttctgccatg gtctctttgc gagccataga ttgttaccat
     5581 actagtctat cagattctga aaagtttggc aagtatttta tcagttttta agcaagtttt
     5641 ttaacttttg gtagatgatt tcgttttctt ctaggctata ggaattagca ccacttgcta
     5701 gagggtggcc tccaccatca tgctccttgg cgatttcatt gataggatgg attttactgc
     5761 gtaagcgaac tcggtagtgg ccatcagcct gttcgacaaa aattccccag agactcactc
     5821 tgtcaatgcg tccaggtgca ccgacaatgg ctgcagtttc agcatcggtt acattgtatt
     5881 gtttcaagac ttcttgactc aggataacgc gagcagcacc attttcatcc acttccagat
     5941 ggtcgtagat gtagccttgc agtttagcaa ttttgtagct catagtgtcc attttgcgag
     6001 tgagagccgc aaagtcaaag ttatgttctc tcaaataagc agccaggcga agagtccgtg
     6061 cagtggtaga agggtagagg aagcgacctg tatcaccgac aattcctgca aagagcaact
     6121 cagcatcgcg atctgccaag gctagttggg ttgtttgggc aaatagggta atcatctcgc
     6181 tagcgctact tgaactagta tcgacccaag acaggtcacc gtatacatca tcatttggat
     6241 ggtggtcaat cttaatgaga aaatcacctt gactatagcg cttatcatcg atacgagcag
     6301 tattagctgt atcacagacg atgacaagtg cgccttggta ggctctatct tcaacaagat
     6361 ccatctcagc catccaagta agagttggtt catcaaaacc gacggctttg atggtttttt
     6421 ctgggaaatg atgttccagc aaggctttca atcccacctg acttcccaag gcatcagggt
     6481 ctggtttcat atgacgatga atgataatgg tgtcgtattc tttaattttt tctaaaattt
     6541 gttggcaaat ctccataaat aacctcaatt ctttctcatt tcattgtagc acaagaattt
     6601 ttatttttaa aatgaaaaag atgtgatata atggagaaag ataaattgag gaggacgata
     6661 tggcattagc aaaaattgta tttgccagta tgaccggtaa taccgaagaa attgcagata
     6721 ttgtagcaga caaattacgt gacttgggct tggatgttga tgttgatgaa tgtacaactg
     6781 ttgacgcttc agacttcttg gaagcagaca tcgctatcgt tgcgacctat acttatggtg
     6841 atggtgaatt gccagatgag atgatggact tctacgaaga cctagcagat ctcaacttga
     6901 atggcaaaat ctacggagtg gtcggctcag gagatacctt ctacgatgaa ttctgtaagg
     6961 ctgttgatga ctttgaccgt gtctttgtgt caacaggagc agaaaaaggt tcagagtgtg
     7021 ttaaagttga tctttctgcc gaggaagaag atattgaacg cttggaacaa ttcgcagaag
     7081 aattggctgc taaagtagga taagcataaa agtgcgctga tgtaatcaat cagtgcattt
     7141 ttcttatcga gagttgggat tttactagcc taattgatgg ctttttgata caataattca
     7201 aataaaggag gagactgtat ggatttagat attattcgtc aagaaatcga tcaaatcgac
     7261 gaccaaattg tcaaactgtt agaagaacga atgcatttag ttgagggggt ggttgcttat
     7321 aagaaagctt caggtaaacc gattttagat actaagagag aagaagttat ttttgaaaag
     7381 gttaggagtc gtgtagagga caagcgctat caggagacta ttgtagcgac tttttcggac
     7441 atactcaaac gttcgcgtga ttatcaggat caaaatatca aatgaaaaaa gaacaatttt
     7501 atccgctagg aatttttcta gctgctatgt tgggcggact tgtccgatat ctagtttcca
     7561 cctggttacc agccagtcca gactttcctt ggggcactct ctttgtcaac tatttgggaa
     7621 ttttctgctt gatttttctt gtcaagggct atctggtcta taaggggact agtaagggct
     7681 tgattttagc actgggtaca ggtttttgcg gaggtttaac aaccttttct agtctcatgc
     7741 ttgatgctgt gaaattactg gatacagggc gttatcttag tttgatactg tatttgcttt
     7801 tgagtatcgg tggaggcctg cttttagctt actatttggg gaggaagaaa tggtaatcgt
     7861 ctatcttgca atcgcctgtg gcttgggagc actcgtacgg tatttctttt cccgctacaa
     7921 tcaagcttct aaattgccac tcggaacgct catagctaat cttttaggtt gttttttaat
     7981 tggagtattc tacaatcatg tagagtctaa ggaagtatat gctattctag caacaggatt
     8041 ttgtggcggt ttaacaactt tttcgacctt gaatgacgaa cttcaaagac tgctaagtga
     8101 taagaaggtc ttttattctt acctgacttt gacttacata ggtggtttgg ttgcgatttt
     8161 tttaggaatt ttgctataaa tttctttact tttttgtgaa aatttggtag actgtatctt
     8221 gtgtgtgatg gacgcacaaa aatacagttt atccgctgag gaagtttcct caagattgac
     8281 aaagatagga gaataaaatg aatccattaa tccaaagctt gactgaaggt caacttcgta
     8341 cagatatccc atcattccgt cctggtgaca ctgttcgtgt acatgcgaaa gttgtcgaag
     8401 gtaaccgtga acgtatccag atttttgaag gtgttgttat cgcacgtaaa ggtgctggaa
     8461 tctcagaaaa ctacacagtt cgtaaaatct ctaacggtgt aggtgttgag cgtatcttcc
     8521 caatccacac tccacgtgtt gaaaaaatcg aagttgttcg ttacggtaaa gtacgtcgtg
     8581 cgaaattgta ctacttgcgt gctcttcaag gtaaagcagc tcgtatcaaa gaaatccgtc
     8641 gttaattcga ctaaaaaact ctgcttttca gcagagtttt tatctagctc ccttagttca
     8701 atggatataa caactccctc ctaaggagta gttgcaggtt cgattcctgc agggggcagt
     8761 aattagacat caaaaaccgc tcaactgagc ggttttagtc tattctttcc ttttacagta
     8821 cccatgtacg aatagcatgg gcaacgccgg attcgtcatt tgttttggtg atgtatttgg
     8881 cgattttttt gatttctgga tttccatttt ccatgacaac ggggtttcca acgacttcca
     8941 gcatggcacg gtcattttct tcgtctccga tagccatggt ttcatctttg gtcaatccga
     9001 gtttttcagc caagtgagta atggctgaac ccttgtctac attctttgta aagagttcga
     9061 ggtagaaagg agcagatttg ttgatggagt agcgctcgta aaattctgct ggaatttttt
     9121 caatcgcagc atcgagaatt tctggttcat cgataaacat acatttaaca atttctttgc
     9181 cagccatttc ttcaggggta cggtagaaga taggcatgct gacgagggtt gattcgtgta
     9241 cagtgtattt tccgatattg cgatttgcag tatagatacc gtccttggta atggcatgca
     9301 tgtggacacc gagcttgcga ctgaggaatt ccatatccag ataatcctca taggtcaagg
     9361 attcgctgat aatctcatgg ccagtagcag tttcttggac aagggcacca ttgaaggtca
     9421 ccacatagtc accttggtct ctcaactgca agtcgtccag aagtttggca acacctgcga
     9481 tggggcggcc agttgcaatc acgactttga caccagcttc tttggcatct tggatggcag
     9541 aaaagacttc aggagtgatt tccttttggc tgttgactag ggttccgtca atatcgacgg
     9601 caattagttt aatactcata aatttcctct tctagttttt atttggggta aaatgatcgt
     9661 tctcaatcaa gtgtaaaaat tgctgggtaa tgcttgcgaa gatgctgttt tggtctaaca
     9721 tttctttagg gaaatagaaa cgattatctc cgtggcgact gccagcaagg gattggacga
     9781 taggagacag gctagagagt tcggccagtt ctccattttt ttgtaaaatc tcaatctgtg
     9841 tccgtgggtt ttcagattcg ggacgataga tatcataagg gaggtcaaag ttcttatgaa
     9901 tggcagtgta gtagtcggga tcaaagccga tatcctcagc taattttctc atgctggcga
     9961 gttggtcttg gttctcttgt gaaaaggtaa tggatttaaa gaccttgcgg ttgacaaagc
    10021 gatgcgataa atctgcaaga atcttgtcag gactggtcat ccaaagctgg aagtaggtat
    10081 tcatcacgcc atcatccaga gccagatagt cagtcaaggt cacatttttt tcgaagaaag
    10141 gcaggaggtg tggagaagtt cgggcaaaga aatccttgtc ctcaggatag agttccttgg
    10201 cgcgtttgag aagattctgt aggagaactt ccatggcgcg tgttgcgggg tggaaataaa
    10261 cctgcatgta catctggtag cgactgagga cgtagtcttc gatggcgtgc atgccattgc
    10321 gctgaaaggc gataccattt tcgataggac gaatgactcg gaggattcga gtcaggtcaa
    10381 attccccata ggatgctcct gtaaaatagg agtcgcgcaa gagatagtcc atgcgatctg
    10441 cgtcaatctg actagaaatg agctgcacga cctgcttatt aggataggta tggtcaatga
    10501 cactggccac cttttctggg aaatcaggtg ccacttgtag caggacttgg tgaatctctg
    10561 tctcaggatt ttgaataatc tcctgagtaa tggcttcatg gtctgtatca aagagatttt
    10621 caaaagtatg ggagtaggca ccatgcccaa ggtcgtgtag gagagcagcg gtcatggtca
    10681 agagagactc ggcaggattc cattcctcag gatatttttc ttcgaaaatc tctgtgatgc
    10741 gtcgtgcaat ttcatagact cctagacagt gagagaagcg actgtgttct ccaccgtgga
    10801 aggtataact ggaagttccc agttgtttga tccggcgcaa acgctgaaat tcttttgtat
    10861 taatcaagtc atagatgatt tgattattga catggatgta gttgtgaaca gggtcacgga
    10921 atactttttc gttcatatga ccattatagc aaaatcctgc tctttttggt aaaatagtag
    10981 gacaagagac aagaaagagg gcctgatgtg aagattcgga tgcgaaatac aattcagttt
    11041 gatgagcagt tggaagtgat tgaccagctt tatgatgtgg aagtgcatga aaaaggagat
    11101 tatagctacc tgcttttcta taatgaggaa aaggaaaaag tagtgattaa atttcatggt
    11161 caagaacttg tgatgagtcg attttccaat cccaagacca ttatgcgctt tctaaaggat
    11221 agtgatagtt tagcctatat tcccacacct atgggtatgc aggagtttat tatccaaacg
    11281 aatcgttatc aagtggatgg gcaaaagatt gaactagatt atcaactaca aaatcaagag
    11341 ggacatccct ttgccagcta tcaattggaa attacttggg gctaggctca tgtctttttc
    11401 aaatttagct atctatcttc ttggatcggc ttcctagtgt ggtagattag ggataatatc
    11461 caaatttcat acagcagtta tattgttatg tacacagaga ttagttttgt actagtctct
    11521 ttctctttat tttaccgaag actattggtt ggataatcct ctcaaatatg gtatactcat
    11581 tactgtaaaa ggagatggat gcctagatgc tgaaaacaca agaaattgcc gataaatatg
    11641 gtataacaag acagacattg aataattgga tgcaaaaagg aataatttct caacctcgaa
    11701 aaaataatcg ttctgcttat gaatgggaag aagaaaatga aaaagagatt gtgagagtga
    11761 tttcagaaga aattcctgca aaatattatg tttcaaataa agagacatta aaaattggaa
    11821 atcgacgcta tctaggaagt aaacaaaaga tgcttgattt catattgaag acagtatcag
    11881 aaaatattgg aagtatcgat agtgtggcgg atatatttgg tggaacaggt gttgttgcag
    11941 acttatttag aaaacagaat aaaaaagtta tagtgaatga tatactctat agcaacttta
    12001 tttcctttca aacttggttt tcgaatgagg atgtagatat tcataaagtt tctcatataa
    12061 ttgatgaatt aaataattta tcccctaaaa aaggctatgt ttctaagaat tttggtggtg
    12121 cttacttttc tgaagaaaat gctggaaaga ttgactcaat tcgtgaagaa attgaaaaat
    12181 ataaatcagg taatcagaga gagtatttca tgttactaac cagtctattg tacgctatgg
    12241 ataaagtggc taatactgta ggtcattatg acgcttatag gaaaaaaatg gattattgca
    12301 aggaaatata tttaagagtc cctgagtata atgaaaacaa tcagaatgaa atttataata
    12361 aagatgccaa taaattagtt aaagaaattt atgcagatct tgtttatatt gatactccat
    12421 ataattcccg tggctatgaa aatgcctacc atgttttaga aaatattgct gaatggaaaa
    12481 aaccagatgt agaaggtgta gcgaaaaaag cagttaatcg ttcagaaaaa gggtcggatt
    12541 atacaaaaag taaagctcct caagcttttg aagatttaat tctaaacatt aatgctaagt
    12601 atatattggt tagctataac aatatgaata aaaaaggtaa ttcccgttca aatgctaaga
    12661 tttcaaacga agaaataatt aagattttat caaaacgagg taaggttcaa gtatttgaaa
    12721 ctgatttctc acctttcaca actggtaagt ctaaaattga aaaccacaag gaattgctat
    12781 atttatgcat aatttctcca gagaaaaaaa aagaaaaaaa gttaattaag agcgctctta
    12841 actatactgg aggaaagtat aaattactcc ctcagttatt acctcttttt cctgaaagct
    12901 acaataattt tattgattta ttctctggtg gagcaacggt ggcagttaat cttgctaata
    12961 ttaataaatc aaaaacgaaa aagtatatca tcaatgatat aagtgaggaa gtaattgatt
    13021 tttataaata tttggaaagt caaaaagatg taacggtatt tttggataaa gtagagaaag
    13081 ctatagaatt ttataaactt tcgaacacac agaaatatag ctatgctcac tacggtgtaa
    13141 atagctctac aggactgggg tcttataata aagaagcttt tctaaaactt cgtcaagact
    13201 acaataagaa aaattataat aaatttgata aggaagtgtt attttatcta ttaattgtat
    13261 ttggttttaa caatcaaata agatttaata ataaaggaga gtacaatctt cctgtaggta
    13321 agcgtgattt taacgctaat atgaaatcta aactaattac gttcattcaa ggtttacaaa
    13381 attacaattt tgttatccaa tcttgtgatt ttcgtaaaac tatgaatcaa gtaaataaag
    13441 gagattttgt atatacagat cctccttatc gcattactac tgccgcttac aatgaaaatg
    13501 gtgcgtggac attaaaggat gatttggatt tgtttaagta tttagatagc ataaacgata
    13561 agggagctta ttttgctctt tctaatgttg tcattcataa caataaagaa aataaagaat
    13621 tgatgaaatg ggcttcaaag tataatttac atgtattaga ttaccattac aataatagta
    13681 attatcagtc taaggcgaaa atgagtaata ctgttgaagt cttgattaca aactataatt
    13741 cgaaaggtga tatatgaggc taaaagagtc aacaagcatt tttaatatgg gtgatacgag
    13801 tattcgtgtt aaagaagttg tccctatcta caaacagatt ttaaaaactc ttcaaaagca
    13861 taatcagtca aatcagaaat ggaacaatga gagtcaagca agtttttatt catcagtttt
    13921 aagcgatttt gcaaaagctg aaacagagga tggaattaac ctttttggga atttgaagag
    13981 aaatgaaata actggtttag acaaaagagg gagaacttta acaaatgctc ttgtcaagat
    14041 tggttttatt aactatgata gaaaattatc tcaagttggg ctgaattata tttctgaaac
    14101 agagcaagct tttgataaat tagaagaact ttttggttta acaattgata atcttgttta
    14161 ttttaggcaa ttattgaagc ttcgtatata tgatagtaac tctgataaat acttctataa
    14221 tttccgtttt gctcttgctt ttttgaacag atatagcaaa gttcctgtta gagattttct
    14281 atggatagtg gaaagcatta agccaaactt ttcagaagaa aaaatcaaag tgattatcga
    14341 taattaccaa tctgtttatg ataacaataa aacttttgaa cagtatagag atgaagagtt
    14401 cgctaatcat atattgattc ctgaaagagt ggatgaagct cgcaaaatgt ttagtattaa
    14461 aaatttttcg gatgaaaact tcaaaaaact ttttccaaat cgaaagaata gtaataaaag
    14521 tttagaatat aaaagttttg ttctttcaat tataaacttt acagaagaaa agacagagcg
    14581 gtcatttgaa gaaatgatga gtctttctaa acaagatgct attaagaaag cttttggaga
    14641 tggtaaggct gttttcaagt ataaaaataa agattctatt caagatttta taactaaaaa
    14701 cagtgataat ccattgctat caggtcaata tttggatata tattatgcat ttacatggtc
    14761 taagcataat gatttgatta aagaatacag tgatatgtgt aaaagaatat tttctttgtc
    14821 tggagtaatc agttttaatc aaggaattgt atcgcttggt cgaccttgga tttttcctaa
    14881 acttttctct ttattaaatg gtaattttaa gctttctggg gaagcaagct atgaagagta
    14941 tgagaacgat ataaagagtt ctttttatca agatatctgt atatcggata ttttagaatt
    15001 atcttatacg caagttttag aaatacaaaa tcagattgcc gaagaattcg gcattgctga
    15061 tatttcaaat attaaacaat ttgtagcaga caaacaggaa agagagttta gggaatttgt
    15121 tgaacaagaa tttggtatca ctaaagtatc tgaagttttg agttttattt ctcaaagaaa
    15181 tgataagaaa gttcaagaac ttgttacgga taatgcctta gttcctacta ttttcgaata
    15241 tatattggcc attgcatggt attatatatc agataagaag tttcaactta gaaaatccat
    15301 gcagttgaca ttttctgctg ataacctccc actatcacat gctggaggca ataaaggaga
    15361 tatcgagatt gaatatagcg ataaaatgct tttacttgaa gcgacattaa tggataaatc
    15421 aactcaaaaa cgtggtgaat tagagccagt tatacgtcat tctgtaaatt tagcattatc
    15481 tactaataaa ccgttacaaa caatatttgt agctaatgaa gtagatgata atgtggttaa
    15541 tatttttagg gctacatcgt ttattcagct aaatggaaca ttaacgaaag gtagcgtaaa
    15601 agggctaaat atctttgctt tgacaattcc agaaattata aatattttgg atagaaagat
    15661 taacgagcag agaattttcg aaaaattaga tgatttttct actatcgaac cttataggat
    15721 agaaaatgga tggcgtgaag agatagtatc tgaaatttta gcatagcctg taggaaatgc
    15781 gagtaattat agaggtttgt ataagacaat tgatgtagaa aggtttgtat tcaatgattc
    15841 aaagaggttc agagtttaga aaatgggatt tacatattca ttctccctat acagtgttaa
    15901 ataatcagtt tgataagctg cctgatggaa gtccagatgt agaaaaattc attcaaaaga
    15961 taaaggacga aggtatttct gctgttggat tgaccaatta tttcagattt agtgatgatg
    16021 actttaagtt aaaagatagg ttaaatgaag aaggaattgc aactttttta aatcttgagg
    16081 ttagattatc aaacattaat aaatcagatg aactttttga ctatcatgta gtatttggaa
    16141 atgaagttca agatgatata gtaaaaaatt tacttggtca tttaaaggct aatattggtg
    16201 atgatgaaaa atcatttaat cgtttaagta aaactgagat agaagataag gctcatattc
    16261 cttttaaaga tttattaaaa gtcttaaata gcgatagaga acttaatggt cgttttctaa
    16321 ctggctttct ttcgagaggt cacggtagtg caactagtga ttctgattct aaaaataagg
    16381 cagtttatga agatatttgt atcaattctg attttttgat tcattctagt aatgaagtaa
    16441 atatcacaaa agatagagaa ttttggcttg ataaatcccc gcatataaga ccactacttc
    16501 aatcctcaga ttctcactct ttggagcaaa taggaagtaa atattcttgg gtaaaagcag
    16561 atttaacttt tgatggtcta gaacaaataa agtatgaacc agaatatcgc attagtgttg
    16621 agaaagaaaa accaactctc aaaaaggatg aacttgtcat tgataagatt ctatataacg
    16681 gtcaagatat ttatctatcc gaaaatctaa atacaattat tggtggtcgc tcaactggta
    16741 aatcaactct actaaattct atagctaaaa agctgggacg agagctgaat ggtgattcat
    16801 attattttga aaatatggat gattttcaaa ttatttggaa agaccagcaa gaagataatt
    16861 ccagacagat agagtatata cctcaagagt atatgtttgc tttagccaga gacaataaga
    16921 agcttaaaga tttggtagga agtattattc aatccaaaga aatgaactct gaattaaaga
    16981 aatatgagca aaattgcgct actctacatc ttgaaattag agggttactt gatagttata
    17041 aagagaacca aaaaaacatt catgagctaa ttaagccaga agcagaaaaa caagctactc
    17101 aaaatcgaat aaaaacatac gaaactaaga aaaaagaatt attaaatgct agtgagataa
    17161 cggagcaaga aagagattta tttgaaaata aaaacaaaga attgcagtta ttgaaaacac
    17221 aaaaagagat tcatgaatct gacttgcgat atgtatcaag tattcttcca attacatttg
    17281 aggttgaaag tttgcccaca acgactactc cgtctcaaga tttaagggtt aaaattggtc
    17341 agattacagc tcggttgcgt gattccgtca gagcacaaca ggaacatgaa attaggataa
    17401 ttaagttaga aaaagaaagt ctaatcaaag ctattgaaaa taaaatttcg gacataggaa
    17461 atgatgacat atacaagaaa tgtgttgagg caatgaaaaa taattcagag atagcgaggt
    17521 taaattcttt aattaagaat gaagttgata ttttagctaa aattgaagcg tttgaaaaac
    17581 aaagggatga attcgataaa gtaacagaag aaattcaaaa agagattatt tcgaaatata
    17641 aggaatactc taatattaga actgaattat tgaataattt caagattgaa gatgataatg
    17701 gagataatct aaagatttca gtcaagttct cattaattga tttggaggct gaatttgatt
    17761 atattaatgc tcgaggtcgt tcgaaacaag attttataga aaaaatgata ggttcttttg
    17821 aagaagttgt tgattcaata tttgacgagg atagtcttgc gtttaatgga aatagggata
    17881 aattcagtca cattgagcat ttcttcacta ctaattttta cgaatatagt tttgagattg
    17941 aatatcaagg tgataaattt gaacaaatgt ctcctggtaa aaaagcgttt attgtattaa
    18001 aattaatatt agagttttca gatagtaaaa tccccgtatt aattgatcag cctgaagata
    18061 gtttggataa tagggcaata tatagtgaat tgacaaaata catcaaaaaa actaaaaaga
    18121 atcgacaaat aatcatagtt actcacaatc ctaatatagt tgtatctggt gatgcagaaa
    18181 atattattgt agctaatcag caatctgata attctccaaa tcaaaatggt aagaagtttg
    18241 attatgtaaa tggtgcttta gagaaccgta ataatgattc tacatctgaa ttcatacttc
    18301 aaaaatacaa catcagggaa catgtatgtg atattttgga aggtggagaa gacgccttta
    18361 ttaagaggga aaataaatac agtattaatg gctaataata attgtattaa ttaaaaatgg
    18421 agagcattaa tttataaaag acacatattt agttctagca aacagtcttt ttaaggagtt
    18481 aggattggta attggactgc cgggtaatgt gtggtataat aaaagttatg gaaatcgaaa
    18541 aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc gcttttgaca gataagcaaa
    18601 tgaattatat cgagctctac tacgctgatg attacagcct tgctgaaatt gccgaggagt
    18661 tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg aacagaaaag attctggaag
    18721 attatgagat gaaattgcac atgtactcgg actatattgt ccgcagtcag atttttgatc
    18781 agattttgga gcgctatccc aaggataact ttctgcagga gcagatagaa attttaacaa
    18841 gcattgataa tagagaataa gaggaagaaa aatggcattt gaaagtttaa cagaacgttt
    18901 gcagaacgtc tttaaaagtc tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga
    18961 ggcaaccaaa gaaattcgct tggccttgct cgaggccgac gttgccttgc ctgttgtaaa
    19021 ggactttatc aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg atacacttaa
    19081 tcctgcgcaa cagattatta aaatcgttga tgaggaactg acagctgttt taggttctga
    19141 tacggcagaa attatcaagt cacctaagat tcctacaatc atcatgatgg ttggtttgca
    19201 gggagctggt aaaacaactt ttgcaggtaa gctggctaac aaactcaaga aggaagaaaa
    19261 tgcccgtcct ttgatgattg cggcggatat ttaccgtctt gctgccattg atcagctgaa
    19321 gacactggga caacagattg atgtgccggt tttcgctctt gggacagagg ttccagctgt
    19381 tgagattgta cgtcaaggtt tggagcaagc tcaaactaat cataacgact atgtcttgat
    19441 tgatactgcg ggtcgtttgc agattgatga gctcctcatg aatgagcttc gtgatgtgaa
    19501 agcattggct caaccaaatg aaatcttgct tgtcgttgat gctatgattg gtcaggaagc
    19561 agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg actggggtca tccttaccaa
    19621 gattgatggc gatactcgtg gtggtgctgc tctgtctgtt cgtcacatta ctggaaaacc
    19681 aatcaagttc actggtacag gtgaaaaaat tacagatatc gaaaccttcc acccagaccg
    19741 tatgtctagc cgtatccttg gcatggggga tatgctcact ttgattgaga aagcttctca
    19801 ggaatacgat gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa acacctttga
    19861 ttttaatgat ttcatcgatc aattagatca ggtgcaaaat atggggccga tggaagactt
    19921 gctcaagatg attccaggta tggccaacaa tccagccctt caaaacatga aggtggatga
    19981 acgccagatt gctcgtaaac gtgccattgt gtcttcgatg acacctgaag agcgtgaaaa
    20041 cccagatttg ttaaatccaa gccgtcgccg tcgtattgct gctggttctg gaaatacatt
    20101 cgtcgaagtc aataaattca tcaaggactt taaccaggct aaacagctca tgcagggtgt
    20161 tatgtctggg gatatgaata aaatgatgaa gcaaatgggg attaatccaa ataaccttcc
    20221 taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca
    20281 aggcggtatg cctgacttat cagctctcgg aggagcagga atgccagata tgagccagat
    20341 gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt ccatgaaacg
    20401 tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga gattgatgca
    20461 aatctcattt gatgagaaaa taaagtaaaa atttctatga taaaacgtac agtatcaagg
    20521 ttttagaata tctgatatta tacgtttttt gattttaata attttgttaa gacactttta
    20581 ttatagtata cgaaaaatcc actcagctgt ctgagtggat taggtgtatt tagactctta
    20641 gtctttattt tcgtatggca agatcaagtt caagatgatt cctgtcatgg ctgaaagggc
    20701 agtacctgaa agtgtaactg gaccaagttt aaggatagct cctccaagtc caagaaccaa
    20761 catagcactt gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa
    20821 gactttcaaa ccattgctgg cgataacccc atagagaagg attgacatac caccaagtac
    20881 agcgtttgga atagttgaaa tcaaggcagt gaatttacca aggaagctga gggcaatcgc
    20941 gatgaaggca gcgttacgga taactgagac agaagcgata cgagtcatac cgataacccc
    21001 tgtattttct ccgtaagttg tattggctgg tccaccaagg aaggcagaaa cagaagttgc
    21061 gataccgtca ccaataagag tacggtgaag acctggttct tttaagaatt gacggccaca
    21121 gatttgaccc aaaacagtat ggtctccgat atgttcagaa attgttacga tagcgattgg
    21181 caagatagcg atggcttctg gaccaaagta aagattgtac tctttaaagg caccacctgt
    21241 gctaaatggc aagtagaaac caggaatttc aaaccagtta gcttctagga caggcgtaaa
    21301 gtcaaccaaa ccaagagtta gtgcgaagag gtaaccaccg ataatggcaa agaggaatgg
    21361 aatgattcgt aggaagcctt ttccttttgt attgataaag gcagcaatta ggaaagtaac
    21421 aacggctacc agagcatttt tccaatttcc gtctgctaca agacctgcat tggtaacagc
    21481 tgaacctgca agtccaagac cgataacgat gatcatagga ccgataatga ttggtggcaa
    21541 gagtttatca atccattttg ttcctacaaa tcggatgctg gtagcaacaa ggacatagac
    21601 caaaccagtc aagataaccc ctgtttgagc agcagataca tcccccccca tttctttcat
    21661 agccagtgac atagctgtga taaaggcgaa tgaagaacct agataaactg gaactttaaa
    21721 accagtagca atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg caacagatac
    21781 aggcattccc aaaatcaatg gtaccaagat ggtcgcacca aacatggcga aaacgtgttg
    21841 gaaactaagg agaattcctt ttccagccga aggacgttgg tcaacgtcta gtaacaaatc
    21901 aacagttgat tcttgtttca tataaacctc acttttgggc atcaaaaaag agcccattat
    21961 tttacagcaa taggccctca gagtaagact tctctaaaat ctagacttta aagagtttca
    22021 aatatttttg cgtcttcgtc acctcacggg atgacattaa aaacctttgc ttaggatagt
    22081 atagcagaaa aaa
//
LOCUS       DAVMBH010000032        21962 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVMBH010000032 DAVMBH010000000
VERSION     DAVMBH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.032"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(229..591)
                     /locus_tag="VYP30_001409"
     CDS             complement(229..591)
                     /locus_tag="VYP30_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1808393.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVDHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSTVSAIDSSEAMLL
                     PIINVLELLDKSQPFEEE"
     gene            605..679
                     /locus_tag="VYP30_001410"
                     /pseudo
     CDS             605..679
                     /locus_tag="VYP30_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(906..1064)
                     /locus_tag="VYP30_001411"
                     /pseudo
     CDS             complement(906..1064)
                     /locus_tag="VYP30_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1337..2026)
                     /gene="rplA"
                     /locus_tag="VYP30_001412"
     CDS             complement(1337..2026)
                     /gene="rplA"
                     /locus_tag="VYP30_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1808394.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2234..2659)
                     /gene="rplK"
                     /locus_tag="VYP30_001413"
     CDS             complement(2234..2659)
                     /gene="rplK"
                     /locus_tag="VYP30_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1808395.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2782..3498)
                     /locus_tag="VYP30_001414"
     CDS             complement(2782..3498)
                     /locus_tag="VYP30_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1808396.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3516..3977)
                     /locus_tag="VYP30_001415"
     CDS             complement(3516..3977)
                     /locus_tag="VYP30_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1808397.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3979..5016)
                     /locus_tag="VYP30_001416"
     CDS             complement(3979..5016)
                     /locus_tag="VYP30_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1808398.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5114..6439)
                     /gene="brnQ"
                     /locus_tag="VYP30_001417"
     CDS             complement(5114..6439)
                     /gene="brnQ"
                     /locus_tag="VYP30_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1808399.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6610..6702)
                     /locus_tag="VYP30_001418"
     CDS             complement(6610..6702)
                     /locus_tag="VYP30_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1808400.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6745..6897)
                     /locus_tag="VYP30_001419"
     CDS             complement(6745..6897)
                     /locus_tag="VYP30_001419"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1808401.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7026..7103)
                     /locus_tag="VYP30_001420"
                     /pseudo
     CDS             complement(7026..7103)
                     /locus_tag="VYP30_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7104..7682)
                     /locus_tag="VYP30_001421"
     CDS             complement(7104..7682)
                     /locus_tag="VYP30_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1808402.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7736..9136)
                     /gene="pepV"
                     /locus_tag="VYP30_001422"
     CDS             complement(7736..9136)
                     /gene="pepV"
                     /locus_tag="VYP30_001422"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1808403.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTVP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKIRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9149..9754)
                     /locus_tag="VYP30_001423"
     CDS             complement(9149..9754)
                     /locus_tag="VYP30_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1808404.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9925..10725
                     /locus_tag="VYP30_001424"
     CDS             9925..10725
                     /locus_tag="VYP30_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1808405.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINHWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10903..11736)
                     /locus_tag="VYP30_001425"
     CDS             complement(10903..11736)
                     /locus_tag="VYP30_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1808406.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11726..13570)
                     /gene="uvrC"
                     /locus_tag="VYP30_001426"
     CDS             complement(11726..13570)
                     /gene="uvrC"
                     /locus_tag="VYP30_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1808407.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13610..14311)
                     /locus_tag="VYP30_001427"
     CDS             complement(13610..14311)
                     /locus_tag="VYP30_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1808408.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14390..15622)
                     /gene="murN"
                     /locus_tag="VYP30_001428"
     CDS             complement(14390..15622)
                     /gene="murN"
                     /locus_tag="VYP30_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1808409.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTIGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15627..16847)
                     /gene="murM"
                     /locus_tag="VYP30_001429"
     CDS             complement(15627..16847)
                     /gene="murM"
                     /locus_tag="VYP30_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1808410.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16959..17738)
                     /locus_tag="VYP30_001430"
     CDS             complement(16959..17738)
                     /locus_tag="VYP30_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1808411.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKCEKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLVVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17807..19468)
                     /locus_tag="VYP30_001431"
     CDS             complement(17807..19468)
                     /locus_tag="VYP30_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1808412.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19643..21865)
                     /gene="recJ"
                     /locus_tag="VYP30_001432"
     CDS             complement(19643..21865)
                     /gene="recJ"
                     /locus_tag="VYP30_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1808413.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFITFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDLPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
BASE COUNT         6280 a         5086 c         4007 g         6589 t
ORIGIN      
        1 tatacataaa ctaacctcct cattattagc aaggcttcta ctgattataa cctaattctt
       61 agactacttc aagactaact gtccaataat aatctacaga taaatcatcc actcttaatc
      121 aaattttatt caatccatct actcattccc aaaaggttgc tgtataatgc aagacatttt
      181 tcttactgct tttacttttc cttaccctca atttagtgag ctaataaatt attcttcttc
      241 aaaaggttga gatttatcta gtaactctaa aacattaatg ataggtagca acattgcttc
      301 actgctatca attgccgaaa ctgttgaaac aatagaacgt aaataaggat aaagaatagc
      361 agtaccattt acgtatagaa tatcggtgat attttcatct atatttattt caaaatatcc
      421 tattacagtt acagatattt ttttcatggc atctttgtca actaaagaaa cactaagttt
      481 tacggctcca tgactataat catctgtatg atcaacctta actatgggat ataatatatc
      541 gaaggtaaat gtgaacaaac tgattaggaa atttaaacca acttctaaca atctgttata
      601 ctcaatgaaa accaaagagc aaactaggaa actagcctca ggttgctcaa aacactgttt
      661 tgaggttgta gatggaactg acgtagtcag ctcaaaacac tgttttgagg ttgtggatag
      721 aactgacgaa gtcagtaacc atacgcacgg caaggcgacg ttgacgtggt ttgaagagat
      781 tttcaaagag tattagaaag ctcgatggac tattccagat tcattccact agatttcgaa
      841 atcgagtagg ggataatctc tagcccctct cacaccaccg tacgtgccgt tcggcatacg
      901 gcggttcaac taactgttaa cgcatgtcgt tcaaggtaat aatccaaaca cgaaaccagt
      961 ccacgttttt caaggactga ttttgatata gcacgtttaa gtaccgactt ttgagctact
     1021 aattgatagt ggtcgcccca gccagatacc ttatccgcta tatacgcctt attatcacgt
     1081 tcctgttcgt agagccacga tttcgctatc ccttcctctg acgattctta tttccagcgt
     1141 cagacttaaa acggtctatc cccagaccgt tttaatccgc tacctcacga tagtcagact
     1201 tgggaatcgc tattgggttc accggtagca ggtgcccacc gaggatttac acctcagata
     1261 tacgacatgc ccgtcgtaca tcaaaaaaag ttgagacata gcgtcttcaa cttttttaca
     1321 ttactttaac tactgattaa agtgagttta cgtcaacttt gataccaaca ccttgagtag
     1381 ttgtgatagt caagtttgtt acgtaagttc ctttagctgt agctggtttt gctttttgga
     1441 ttgtttcgtt gaaagcttta aagttttcaa ccaatttttc agcttcaaat gatactttac
     1501 cgatgattgc ttgaacgtta cctgcacggt cagcacggta agtgatttta ccacctttag
     1561 actcttcaac tgctttagca acatccattg ttacagtacc agttttaggg tttggcatca
     1621 agttacgtgg tccaaggaca cgtccaagac gtccaacaag agccatcata tcaggtgtag
     1681 cgataactac gtcgaagtcc aaccaaccgt cgttgatttt agcaacaagg tcatcttcac
     1741 caacaaagtc tgcaccagca gcttttgctt cttcagcttt tgcaccacgt gcgaaaacaa
     1801 gaacacgtga agttttacca gtaccgtttg gcaataccat tgctccacgg atttgttggt
     1861 cagctttttt aacgtcgatg ttcaagttgt aagcaacttc tacagttgca tcaaattttg
     1921 caaagttagt ttcttttgca agtgctacag cttcttctac actgtatgct tttgtgctgt
     1981 cgattttctc aagagcagca cgaagttgtt tgcttttttt agccattttc tattctcctt
     2041 gtaagtggtt caatcgattt tcatctccca cgtcacttct cgaaatgatg aagtcttgcg
     2101 ggttttcagt ctactatttt tctcttccta cggccttaag ctcccttgct gtacccaagt
     2161 acaaggctca gtcacttgcc tagtatgaaa agcaactaat agactgctgt gagattttct
     2221 actgtgttat tgattagtca acaacagtga atcccataga acgagcagta ccttcgatca
     2281 tacgcattgc agactctacg tttgctgcgt tcaaatctgg catcttagtt tctgcaattt
     2341 cttgtacttg tgcacgagta actgtagcaa ctttagtttt attaggtgta cctgatcctt
     2401 tttcaacacc tgcagctttt ttcaaaagaa cagcagctgg tggtgttttc gtaacgaaag
     2461 taaatgattt atcttcgtaa actgagataa caactggaat gatcatacca gcttggtcag
     2521 ctgtacgagc gttgaactct tttgtgaatc ccatgatgtt gataccagct tgaccaagag
     2581 caggtccaac cggtggagct ggtgtagctt taccagcagg gatttgcaat tttacaagtt
     2641 tttcgacttt tttagccatt tttaaatcct cctttgtggt tttggcggta attagagatt
     2701 tttacctccc acaagtatgt ttttcacata cccatccatt atacactatt tatctggaat
     2761 tgcaagagaa aactttcatt tttaatcgac ataatcgccg ccttcaaagc catagtactc
     2821 ttccaaactg agaccacttg cagcaatttc tttggcttct tttccaacgt agcggagatg
     2881 ccattcttct gccatgtagc cagtctcctt ttccttgcct ttaagatagc gaacaacaaa
     2941 gccatagtca gccgcatggt ccaagagcca ctgggctgcc ttttcttcag taactaaatc
     3001 cccatctgtc ccaatcaaat caaaagcaag acccgtctgg tgttcactgt aacctgggcg
     3061 tgctgagtag cgatctgctg cttccttacc atcttgattg acatagtctt ggtagagctt
     3121 agcctgagtt tcataactcc taaacccact gtattggtca ctgattggat agccctcagc
     3181 ctgcatagct gcgattagtt tgagcaactc tgccttggct gttggatttt ctcctggatt
     3241 gtaatctttt gacaaaggat aacgtttatt agctaggata atctcatcgt atttcccttg
     3301 gatactataa tagctccctt tattgctaac ttctgccttt ttctgactag aagcttgaga
     3361 tttgctacct acagttcctt ccggttgact gctttgctcc gttttttgag tgttttcttc
     3421 aactttggtt ttttcttgcg aacaagctgc aagggtcaat gctagtaaac cagataaaat
     3481 gacatatctt tttttcattt ctttcttcct ctctcttagg ccaaatactt ctccaattca
     3541 tgagataaga ttttaatcat ctcttccagc tctggcgatt gtacttggca atcttctgcc
     3601 gccatttctt cccagggcac ccaccagact gggccacggc cattcaaacc gtgactcttc
     3661 atatcacctg ctcttcgggg aaaaagatgc caatgagcgt gggcatcgcc atttcctagg
     3721 agttcaatat tcatcttttc agcctcaaat gctttggcga ctgcttcttg gactaaactc
     3781 atttcctcta aaaagcgaag ttttacagaa gtttccatat gatggagttc tgtgacatga
     3841 tcttttgcta aaaataaggt atagccctta aagtattggt agtcaccaat aacaacatag
     3901 cctgtttcta gttcttttac aaagtaggga ttttgcccag ctttaatgag ttcgattctc
     3961 tgacagatta agcacattct atgataccgc ctcgctctta agataagcat caaccatacg
     4021 ctcagtcgct actactgaat cgatgtgggt gcgctcataa gagtgactgg actcaatacc
     4081 agctccaaga agtgcatgct tgacctctgc acctgctgac atcgctgctg aagcgtccga
     4141 tccgtaaaat ggatagatgt cgagcttaaa tggaatatct tgctctttag ccaaggcaac
     4201 caagtgttga cggaagtcat agtgataagg acctgaagca tccttgacac agatagatac
     4261 tgtgtactca tctgtctgct ggtcatctcc catagctccc atatccacag ccagatattc
     4321 tactacctga gcaggaatgt tagaattagc accatgtcct acttcttcaa aaactgaaaa
     4381 agcaaaatga gttgttactg gcaattcaat cttctctttc ttataaatac gaagcaggtt
     4441 gagcaaaatc gctgcgctga ccttatcatc caaatgacga gacttgataa aacctgtatc
     4501 agtcacaaca gttcgtggat cgaagctgat aaaatcaccg acctcaatcc caagagcacg
     4561 agtttctttt tcattgctta cttttacatc caaacgcact tccatattgt cctgcgtgcg
     4621 ttctgcagtt cctgcatcct tgtagacatg gcaagaagtt tggtggatga ggatggttcc
     4681 tgataccttt tgacctgtgc tagccacatg aacggtacag ttttcacctt caatcatgtt
     4741 ccaaggaaaa ccaccgatac ggtccaattt aagacgacca tctggtttga cagcacgaac
     4801 aatagcaccc agcgtgtcca catgggcagt cacatagcga tgttgctcat cattttgacc
     4861 tttgatggtc acattgacac cacccttggc tgtgcgaact ggctggtaac caaaaccttc
     4921 tagagtcttg actaaataat tcgaaatttc acgagtgaag cccgttggcg atgcgatggc
     4981 tgtcagttct ttgatatatt ctactgtttg attcatttct tcacctcttt cgctacctat
     5041 tataacacat ttatcatcgg ataaaaaaag aaaatcactc ctgtagactt ggctacaaaa
     5101 gtgatttaag tgattattcc atttcaaaaa catcgctttc ttgcttgttt ggtagaacca
     5161 atgagagcaa gattccaaca atggctggca ccaaccatgg gagagatgcc ttggcaaaag
     5221 gaagaacgct aacaagattt gcaagaaact caaccttaaa cgagcttcct agtacgcttg
     5281 caatggcaat aactgtaacc acagcaattg tcaactgcat acctggtttt gaaagggcaa
     5341 caaatttgtt gacaatgaca atcataacga tagcaatcgt gattgggtac aagataacca
     5401 gtactggaat tgagtacttg ataatcgcat caagacccaa attggcaata gcaaatccaa
     5461 tcaaggtaaa ggctgtcgca taaaccttgt agctgatttg tgggaagcgc tcattaaaga
     5521 actcagctgt tgacacaatc aaaccaacag tcgttgtgaa gcaggttacg gtaaccatag
     5581 ctgcaaggaa gagttgagct gttgagccaa agatttcttg agtggcttgt gacaagatgt
     5641 aaacacctgg tgttccaccc ttcatcgctt cagctggtac tgggaaatga tttccaagaa
     5701 aacctaaacc gatgtaaaga gcgctgaagg caagggcaac aacgatacca acaacccaaa
     5761 tagttgaaat gtattctttc ttacttgaaa atccaagttg tttcaaggtt tgaactgcga
     5821 ttacgctaaa ggccactgaa gcaagggcgt ccaaggtatt gtaaccttct aggaaacctg
     5881 taccaaaggc agaagcttga taagcagctg aagcagcttg aggacttgtt ccaccatatt
     5941 tgatagctcc cagaacgacc aagataacaa tcaaaattgc aaagactggc gttaaaatac
     6001 gtccaatgcg gtctaagatt tttgatggat taagcgaaat caaataggct gccgcaaaat
     6061 acagaaccgt aaatacaatc aagccaagtc ctttatttgc atccgacaaa agggggctaa
     6121 tccctacttc gtaagctgtt gtagcagtac gtggggtagc aaagaatgga ccgattgaca
     6181 agtaaagaac tgagaggtaa agagtcgcaa accaaggcgc tatcttcgtt gaaatctcgt
     6241 agatatatcc tttaggattt agcgttccaa taataagggt caagacggcg ataccaacgc
     6301 ctgaaaagac aaaacctgcg atggcaggaa gaaaatgttc tccagataga gcacctagag
     6361 aaggcggaaa aatcaagttc cccgcaccaa aaaatattcc aaacaggagc aaacctgtta
     6421 gggtaccttt tttagccata aaaatctcct tcatatttat aaaatactga cctagtatac
     6481 cacgattagg agtctgaaaa aagcatcacg aggcaaatat taaatgtttt caattttctt
     6541 aaaaataaga attatctaaa aataaaactc tcctactcag tccacaccaa gtaggagaaa
     6601 tgcaaaattt taaagttctt caaaggctaa catgccaccc tggacattga taacattata
     6661 accttgttct aataggaatt ggcaagcacg cgccgatctc attccagatt tgcaaataat
     6721 ataatgcaag cgatctttgt ccaattaatc ataactatca gccaattgac taagcggtag
     6781 gttgtgggca ccttctaaat gaagagctgc aaactcatcc acttctctca catccactaa
     6841 agaaagctgg tcgttttggt aaagctggta aaatgcgtca aaggctattt ctttcattct
     6901 ttttcttcta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtgcg
     6961 tatatgtaac tgacttcgtc agttttatct gcaacctcaa agcagtgctt tgagctgact
     7021 tcgtcagttc catccacaac ctcaaagctg tactttgagc agcctacgac tagcttccta
     7081 gtttgctctt tgattttcat tgactataaa atggttttaa ttcttttttt caaatctggc
     7141 actacttctg cctcaaacca aggatttttg gccatccaga tttgatttcg tggtgatggg
     7201 tgaactagcg gaaaataggc tggcagatag tctttatagt gtttcaccct ctccgttacc
     7261 ttcccactga ttttctcctg taaatagtag gcttgggcat attgcccaat caagagggtt
     7321 aactgaatat caggcaattc ctgtaagagc tgcggatgcc atttttctgc aaaacctgta
     7381 cgaggcggaa gatcacccga cttgccatgt cctggaaagt agaaatccat aggcaaaaca
     7441 gcaaaataac ctgaattgta aaaggtatct tcatccacac ctagccagtc ccgcaagcgg
     7501 tcaccacttt tatctttcca gtaaaggcct gcttcttgag ttttaagtcc cggagcctga
     7561 ccgatgatat tgatgcgagc agtttttggc gctgcaaaga gaggctcaat gccacgctct
     7621 gtatagctgg cattctgtga atccgccatg atagcctgtt tgattctttc gatttgagac
     7681 atctactttc cctccaaaaa gaagtccaag cataagatct cagacttcta tcgttttatt
     7741 tgatcaattc gtaaatagct tcggcataaa ttgctgctgc tcggaaaaga tcatccaagg
     7801 cgataaattc attggcttgg tgcatggtat caatcgagtc tgggaacata gcaccgtagg
     7861 caactccgcg ttctagcaag cgaccaaagg ttccaccacc gatgacttgt tcatgacctt
     7921 taaggccagt ttgtttttca tagacattca acaaggtttg cacaagtgga tcttccattg
     7981 gcacatagtg aggcgtgtga ccgtgttcag acaggctaac agaaacaact ggcaagtttt
     8041 caaggattga cttgatttgt tctggacttg ttccttttgg atagcggatg ttgagggcaa
     8101 tggtattatc agcacttgtt tcatcgaagc ggaagacgcc ggcattcata gaaagagcac
     8161 ccatcttttc atccacatga gcaatcttaa gattttcacc ctcatgatcg ttcaagagaa
     8221 ttttacctgc gatgtcaagg taatctttgg ctggaccagc aaagccaaac tggctgagga
     8281 agagggcaag gtaagttgcg ccattgacac ctgaagcagg catagcaccg tgggctgatt
     8341 taccaatgat cgtcaccttg tatttgccag cttcttcttg gagttctcct ctaagtttgt
     8401 gttctgcaac aaaggcatct agtttagctt gcaagtcagc caaatcacct gaaacgactg
     8461 ctgttgctga ttctggtacc atattttcac gtaaaccacc tgtaaagctg tgaagacggg
     8521 cagcacctgt attttctcct gcaaagtgga ggtattccgt gatatttcct ttttcaccat
     8581 tgatgattgg aaattcagca tctggtgaga aaccgaaatc tggtttggca agtcctacgt
     8641 gctcaaagta gtagtccatg tctgcccagc ctgattcttc gtctgttcca acgatgaagc
     8701 gaattttctt agaagttgga agacccaatt ctttgatgat tttcaaacca tagtaacaag
     8761 ctgttgtagg acccttatcg tccgaagccc cgcgcgcata aaggcgacca tctttgatag
     8821 ttggtgtgta aggaactgta tcccaaccgc taccagctgg aaccacgtcc atatgggcaa
     8881 agattccgag aacttcttct ccatcaccaa actcaaaatg tcctgcgtag ttatcgacat
     8941 tcttagttgg gtagccatcg cggtctgcga tttcaaggaa tttctccaag gcttttactg
     9001 gaccaggtcc aaatggatgc tgggcatcag ccttgctatc atcacgttct gagttgattt
     9061 ccaaaaggct aaacaagtca gccaagaggt cttctttgcg tttttctact tctgctgtaa
     9121 aatcaattgc tgtcattttt tcttctttct atcttttctc gatgatttca tctactggca
     9181 agcggtagct tggttccaat ttttcgtctg tataacccac tgtgatcaag agttctgggc
     9241 ggaaacggtc ttcgatttcc aaaacttcat taacttttga tttgtcaaaa ccaagaataa
     9301 tgttagaacc aattccttgg tctgtcaatg caagaaccaa gttcatggca accaaacctg
     9361 cattgagagc taggtagtcg ctgacttgtt gctcattgta acgggcaaac tcagctggca
     9421 aatttttcat gaagtattga agttgttctt ctgagaaatt gttagcacca ccaactcggg
     9481 caatcttacg agcgcgtttg gcaaggtctg tatctgtaaa tagggcaatg gttacaggtg
     9541 ctgatgatac ctgctcaaag tttgaaccat aagccaactt tgccagttca gcatttttct
     9601 cacgaacaac tacaaatttc caaggctggc tgttgtgggc gcttggcgcc aaggttgcaa
     9661 tttcgatagc cgtacgcaca tcttttggat caacaggctt atcagtaaaa tgcttagtcg
     9721 catgacgttt tttatttaat tcaagaaatt tcataatcga tttccttttc taattctact
     9781 gcttccattc taccataatt tgaaagagct tgcagggatt tttcatgatt aagtttttct
     9841 atcacagaca taaaagatat atattggttt atcaggaaag tttctgataa actagcaagt
     9901 actttacatt tgaatggaga cagtatgaaa aaatttagcc tattactagc tatcctacca
     9961 tttttggttg cctgtgggaa tcaagctaca cccaaagaga ctagcgctca aaagacaatc
    10021 gtccttgcta cagctggcga cgtgccacca tttgactacg aagataaagg caatctgaca
    10081 ggcttcgata tcgaagttct aaaggcagta gatgaaaaac tcagcgacta cgagattcaa
    10141 tttcaaagaa ccgcctggga aagtatcttc ccaggacttg attctggtca ctatcaggct
    10201 gcggccaata acttgagtta cacaaaagag cgcgctgaaa aatacctcta ctcacttccg
    10261 atttccaaca atcccctcgt tctcgtcagc aacaagaaaa atcctttgac ttctcttgac
    10321 cagatcgctg gtaaaacaac acaagaggat accggaactt ctaacgctca attcatcaat
    10381 cactggaatc agaaacacac tgataatccc gctacaattg atttttctgg tgaggatatt
    10441 ggtaaacgaa tcctagacct tgctaacgga gagtttgatt tcctagtttt tgacaaggta
    10501 tccgttcaaa agattatcaa ggaccgtggt ttagacctct cagtcgttga tttaccttct
    10561 gcagatagcc ccagcaatta tatcattttc tcaagcgacc aaaaagagtt taaagagaaa
    10621 tttgataaag cgctcaaaga actctatcaa gacggaaccc ttgaaaaact cagcaatacc
    10681 tatctaggtg gttcttacct cccagatcaa tctcagttac aataatactc ttcgaaaatc
    10741 tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg tgctttgagc aacctacggc
    10801 tagcttccta gtttgctctt tgattttcat tgagtataag atatataaaa gcgattggac
    10861 taccaatcgt ttttagtttg cattggttat tttaggaaac tcttacaaaa aatcaaaaaa
    10921 attcttcaca tcctctacat acccatgctt ttctattaag cttgctaata attccagatt
    10981 gtgcccctga tagttatcgt cacgacgcag ttcttcatac atttcgataa agggaagtcc
    11041 cttggacttg gccaattcta actcagcctc gtaatcataa gcaactttac gaaataggat
    11101 atttaccaat tccccatctt caacctctat cacggcatac tgggcacggt gattttttaa
    11161 cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga ttgatgattt gttgcccttg
    11221 actaccataa cgaagcaact gcttgtgaac atgaccataa actgccacgt ccgtttccgc
    11281 atctagcagt tggtcaaatt tctctgtatc attctcaact agcaagtcac caccatagtt
    11341 tttgtcaggt aaattatgag agatagaaaa gcgcaatccg tcaatttctt tcttttccag
    11401 caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc attcgctcca tcaaaaactg
    11461 ggtcatgcgc attgactgga tttctttcgg atattccaaa ccatattcgc catccaagac
    11521 ctcaaggaca cgatcatccc aattgcctcg aacacttgct gtgataggaa ggtcctttag
    11581 cagggcgact aagtcatttg cgcctggacc aggaagaaaa atatctccca gaagccaata
    11641 ttcactggcc ccttgatttt tagcatctgc aatcactgct tctagcgccg tcgcattgcc
    11701 atgaacatct gataaaattg cgattttatg gttcattgtg gtttccttcc gtttggtaat
    11761 ctactctttc ttctgctact tgaggcaagg cttctccctg cgggttcaac tttctttgca
    11821 cagcctctgc aacgactcta ggtaccccaa cttcgacaat ctcatccaca ctggcttcct
    11881 tgattttggt caaagacttg aaatgcttca taagattctg cttgcgttta ggtcccagac
    11941 cgtcaatccc atccaattga gatgagaaag aatttttgga gcgcagttgg cggtggaaag
    12001 tgatagcaaa gcggtgcacc tcatcttgga tgcgttggag gaggaaaaat tcctgagaat
    12061 tgcgagacaa gtccaccacc tcaagcggat ctccaaagag caattcatgg gtttggtgct
    12121 tatcattctt ttgcagccca gcaattggaa tatccaagcc cagttcctct tggataacct
    12181 gcttagcgat attgacttga ccttgccccc catcaatcac aatcaaatct ggaggagtca
    12241 aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac ctctctcatg ctggcatagt
    12301 cgtctggtcc aacaaccgtt tttatcttgt acttacggta atccttctta ctcggtttac
    12361 cgttgacaaa gaccaccata gccgaaacag ggctagttcc catgatatta gagttatcga
    12421 aggactcgat acgtactggg gtcgggattt ggagcaaacg ccctagattt tcaatagctc
    12481 cttgagtctt ttcgacagat ttttctagca ggttaaattt ctgctccaga ctaacacgtg
    12541 cattttttat ggctagattg accagttgtt ttttctctcc acgttgaggc ttaagaatct
    12601 tggaatccac caaggccttg acagcctctt cgtcaatatc ctgcggaatc agtacctcat
    12661 tgggaactag atgagatttt tcttgataga attgtcctac ataggtcaaa aaatcctcat
    12721 ctggatcatt gaagtagggg aagagattga catcgcgctc gataagctta ccctgacgga
    12781 caaagaaaac ctgcacacac atccagccct tatccacata gtagccaaag acatcgcgat
    12841 tttgcaaatc tttcgccatg acccgttgct tggttcgaag cgttccaata gcctgaatca
    12901 ggtcacggta ttccgccgca cgttcaaact ccatactttg tgctgctact gccattttac
    12961 tcttgagatc atcgatgatt ttgttatcct gccctttcag aaaatcagaa acctcctggg
    13021 ccatagactt gaaataagtc tcatccttct tacagatggt gtgggccatg cattgaccga
    13081 tatggtaata aaaacagacc ttagagggcg ggttggtaca cttacgaaaa gggaatatcc
    13141 gatccagcaa ccgcttgatt tcattggctg cccccacatc gggatagggt ccaaaataaa
    13201 gacctccgtc ctttttgacc tgacgagtga taatcaagcg tggatagcgc tcattggtga
    13261 ttttgatgaa aggataggac ttgtcatcct tgagcatgat attgtacttg ggcttgtttt
    13321 ccttgatcag gttgatttct aggagaagtg cctcaatatt agactccgta acaataaatt
    13381 caaaatccac aatttcagac accagagcct ctgtcttggt atcatgactt ccacgaaaat
    13441 aggaccgtac tcgattacgc agatttttag cctttcctac atagataatg gtgccatttt
    13501 tatccttatg aatgtagcaa ccagggctgg tcggcaagag ctctagtttt gatttaatca
    13561 agttgttcat agttccatta tagcaaaaaa agtagggaaa gatagtaccc tactcactag
    13621 tctcatatat ttttcggagg tttgcaacat cctcttcctg gataccataa aaggaacctg
    13681 ctggttgcat gacagacttc tcatctgtat ggtccaagcc aatcgcatga cctaactcat
    13741 gttctgccgt atggacaagg cgttcatagg agtagccata gtatggattg gacaaataat
    13801 aatgattcaa ccgcaccgtt acggacaaga attgccctgt taagagatta gtttgacttt
    13861 ccgcctctcc tgccacagga gtgcctccgt cgttcatctc cgtagccgta atatccgcct
    13921 tactagactc agtcacgagt tcaaagttaa aagcaccagt ttgattccag ttctggattg
    13981 cttctaaata agcctcttga aagcgtgaat ccatctgcgg atccaggtaa atacgagcag
    14041 aggcctgtgc ccaccttcct tcagaatgct ggtgactatc tgtctggctt aacttaggca
    14101 gttgccctgt tttctcccat tggtcaatac tttgttgacc aatttttact gaccgttctg
    14161 cttgctttag cgctccttga aaatccccgt tcagatacca gagaagtccg aaagcaagca
    14221 cacataagag cacaactatc caaaccagac gccaaaacaa acgccacaca aaaaaaaaga
    14281 aagctcctat caaacgaaaa agccagcgca tgtctctcca cctttctagc aaataagaat
    14341 tattttacta aaagaagcta aaagaaatct aaatactgac tttttcatct taacgtccta
    14401 ctattttttt gagtaactgg atagctttgt attttaaagg cgatggatgg taacggaaag
    14461 tacccgcttt gcgtacaata tagccattaa aattctgttt aaaacgcaaa acaccatcac
    14521 ttccatcaaa aatcccttga atgcctagga agttgtattt aggtattcca cgttttatgc
    14581 tttccaacat aacatatttt tgaagcaggg caggggcata gaacttatta aactcagtgt
    14641 aggaaccact aaagagataa gtcgtttcct gaggcatata aacaaataaa ctaccagcta
    14701 aaacaatatc ttcttctcca tatttttcaa tcaagtctcg cgcttctgct tttcgaactt
    14761 caaacgtttc aaattgacta gaatattctc tcagttgatt ttgttttttc tcagaatgag
    14821 gatttttact caaatcaagt cgcaacttgt ccaagttttc ttctagttta ctttgttcac
    14881 cttgcaattt gctcatatag tccgaaaaat ttaagcttgc tatgagaaac tccgcttgtt
    14941 ctccaaaagt atcataaaaa tgctcataat attctaaact tttatcacta tattctctac
    15001 gttcagaggt ttcttttgtt atattcttaa aaatcgatag ttcttcacgt tttaactttt
    15061 tcaaccgaat gccaaaggtt tcagcctttt tcaccaaggg tttacccttt ttgctaaaac
    15121 ttttaagcaa actcttttca gttaattcag ttaaatcttt atagtataac caatctggtt
    15181 ctccacctgg gtaacctatt gttaagccat caaattgata acctaaatca gtcaaacctt
    15241 gaataatact ttttttctca gcatctattg gattaccttg gctatcaaaa gtttgataag
    15301 tttcataagg ttttacaagc aactctaata caccattttg cttggcatat tcttttaact
    15361 ctgcataaaa aactggaaga gcatcttgtt gggtataaat cggccccgaa ttgagttcca
    15421 tatgcagacc acccagcatg ggcaagctat aaaccagagc tgcaacttga atttctcctt
    15481 cttgtttcaa agcaagataa acaattcgag cccctctttt ttctagcaaa tcccccatct
    15541 ggacagattg cataaaggaa cgagaagaaa cctgatcaga ataagtctga aactcttctt
    15601 tcgtgagtgt tgttagtgcc atatacttac tttctatgtt tttttcttaa tgttttacgg
    15661 aaatcaagag caagtcttaa cagaggatag agaggatgag tgggcattgt aaattcaccc
    15721 aagtattctt caatcgttgg attaaatttt tccttaaaat gataaagtcc accattgaga
    15781 gagttttcaa caccacctaa attttgccag accatacctc gctcaaaggc atagcgagcc
    15841 gtttcatacc atgttaaaat tggtgcattg taacgtttaa aatcatcatc cataccagca
    15901 tatatattga cagaggtagt accaaattcc aaactcaaag tagccgctaa aggaactctc
    15961 gcttgaccta catctatata ttcctgcaag aaggtcaatt cctctaacaa acgttctttt
    16021 tccttcttct gcgcttctac ttttgaagtt cgagtcgact cagtaaacgt ctcttccaag
    16081 gctctatttt tcgctaactg ttcttctaac tcttgcgaac gtttagaaac atccaaggtg
    16141 gccaaggtga tataggcctt gtccttaaaa ttatctaaca attttttata ataggcttca
    16201 ttcctcaaat gaatctcttt tcgcttctca gtttttttca tcaactccga aaatgaatct
    16261 aatagttcca gtccaccata ttgaatctca agccctttgt ttcgtgctgt tcgaatagcc
    16321 tgttttgttg acttggaaag tttatcttct tcaaaatttt ccttgtatat tttcgcctga
    16381 atacgaggtt gaatggtgtc tcccatttcc tccgtttttc ctgaccacct tactcccatt
    16441 tgttgcaaac tatcaataat agccagattt tcaggaaatt ctgtcttttc ctgattgatt
    16501 aaactttgag ataggcaaat acttgggtca aaagtcacaa aaaccgctct cttactgcga
    16561 gcataggact taatagactg aatggcaaaa ttcaagagtt ctttatcccc ataatccaat
    16621 ataggtcctc ttgggatgta aaacatttta tagcctagcg gaagagttct aatcaaaata
    16681 ctagctgtcg ccagtaattt ttcttccctg taaacaccaa acttctcatg ttgccaatta
    16741 gacttaactt cctcccaagc actactttgt aatacattgg ctaattcatg ttctttgaca
    16801 aactgatcat attctaatgt gggaatgcca atttgataac ggtacatttc ctactctctt
    16861 tcctccagta ttttattact attctactac tttcgtttga aaagtctagt gaaaacatat
    16921 tttattttag ttctactccc cctatgctga agttcaaact aagtcagtct ctcttctaat
    16981 ttgaaatcaa ttggtagggt tgttaaaaaa acttccaatt gtttttccca gtagtaccac
    17041 tcgtgagttc cagcgctatg gctataggtc acatcaaaac ctagtttttt gagatttttc
    17101 actacgagat tattggcttc gtacaagaaa tcctgttcgc cacaccacgc ccaaagtttg
    17161 gtctttttat ccgatttttt agccagactt tcaagagaat agggactagt tgtccagtct
    17221 ttaatctctc caaaaacacc tctccagtag gctggacttc ccagattttg actctcagga
    17281 gaaaaatctt gaaagctcaa tgcacctgaa aagctagctg catgagaaaa acgatttgtc
    17341 gcaagagcca gtttgaagca gccgtagcct cccatagaaa gaccagcgat aaaggtcttt
    17401 tcacacttgc tagtcatatt agggaagaag cgtttcagaa cctgtggcaa ttcctctgct
    17461 aaagccgtgt agtagtcaaa accatactgg gtatcggtgt accaaccatt gctggtattg
    17521 ggcataacaa cgatgagatt agttcctcga agcaagcgtt ctacattggt ccgcttaagc
    17581 caactattat gatttccaga catcccgtgt aaaaggtaca agacgggaat atcttcacac
    17641 tctggttctt ccactcgatt ggcatcaggg tagaggacat tcacccccca ctccatatcc
    17701 aatacttgtg agtaatactc gattttcatt actgccatga ttttctcctt ctatttttct
    17761 ataagaaaaa gccgaaactc gactttctct ctgtttattt caacgattat tttgcttcca
    17821 tgactactgg taaaatagct ggacgacgct tggtttggtc aaagagatac ttggtcaaat
    17881 tatctcgaac cttcccttta agatctgccc agtcaaagtc atctccttga agatactctt
    17941 ctaccgtttg gttaatcaat tctgaacttt cacggagaat atcgcgactc ttcttgagat
    18001 aaacaaatcc acgcgtgtga acacgagccc tagccacaat tttcttctca cgacggttga
    18061 ctgtaatagc cacgatgaaa attccatcct ctgacaagac cttacggtca cgaagaacaa
    18121 catttccaac atcaccaatg gcattcccat caatcaagat atctcctgct gaaaccgatc
    18181 cagctggaac aaagtctcca ttctcgtaag ccatggtcgt ccccttttta ggaatgaaga
    18241 tgcgttctgg caacatccca actgccatgg cagccttagc gtgagcatcc aactcacgat
    18301 actccccttg gacagggaag aggtacttag gttgcaaaag attgatcatc agctgcaaat
    18361 cacgcacatt tccgtgccct gatacatgta aactttgggt aatcaatttg acaaccccac
    18421 ctgcctgata aatcatattt tccacacgcg caacaaaggc ttctttagca atagacggag
    18481 ccgtagcaat atagactagg tccccatcct tgatttctac ataacgatgg cgaccaatcg
    18541 acatcttacg aagtccattg ataggctcac ccatacgacc tgtctcaaga ataatcaact
    18601 catggtcttc aaagcgagac atatctttag gcttaatcaa aagaatttcg ttggctaaag
    18661 acaacttctt aagacgaatc gctgtgcgga cgatattttc aatatcaaat cctgtcaaga
    18721 cgatacgtcg acctgtttta tccgcagcgt caaaaatctg ctgaatacga gaaagattac
    18781 tggaaacagc tgcaacgatg atacgacctt cccagtcagc aatagtttgg gtaatttcat
    18841 ccctaacttc actttcacta gccacctgaa tattgctgtc tgcattggcc gaatcactga
    18901 ggagagccag gacgccgtca cgaccaatct ctgccaaacg agcaaaatca gttgcataag
    18961 attcactagc cgtttggtca aatttgaagt cacctgtata aacgatgctt ccttccgatg
    19021 tcttcaagac aattcccaga ctctctggaa cggagtaagt cgtagggaag aaggaaacca
    19081 ctgtcccacc aaaatcaatc tccgtattct catcaatgac atggaaatca ttaaatttct
    19141 taacggcatc atttcctttg acaaagagct ttgccaactc aatggtcaac tcagacccaa
    19201 atacaggaac tttagcctct gccaagagat acggtagagc accaatggca tccgcatgcc
    19261 cgtgggtcaa gaaaacccca gcaatacggt cgctattttc aaaaaggtaa tccatgtttg
    19321 gaatcaccac atcgacccct aattgttcat tttcaggata ttttaaccct acattcaaaa
    19381 caaaaatgga ctctccaatt tcagcaatgt acatattttt tccattctca cgcacaccac
    19441 caagtgttgt taaactgata ttactcattt ttcctccaaa atcttagttt atcttgatta
    19501 tagggcaatt ctaccctctt attctaaaag ttctgatact ttcagccgaa tcttttccta
    19561 ccattatacc atttttttga tgattttcaa aatgaaggtc tgttttcaaa aaagagttga
    19621 tttcccaact ctttcctaac ttctactctt tttccatcaa aaaatcataa atttcttgca
    19681 ccgtacccag cgccatcatt tcttggtctt taacggtttg tttgagattt tggtaaattt
    19741 gactttctcc tatctcccgc tttggcgcct ctttattgac tgtcatcaca ccatctttta
    19801 tcgtcacaaa gcctagttct tcaaatactt gaatcatctt gaccagcaag atttgttgaa
    19861 tattaagata tgcagccaaa tctttcagct tgtagcgaat atcaaactct gggaactggt
    19921 aaatagtctt gtacaatttg gcaaactgat ctctagtccc ataacctgtc agataataag
    19981 ccttgtcaat atcatttttg aaatagacag cagagaaatg ctgttcctga aaaatggtct
    20041 tcagctgagt aatatcctct ggaatgtttt ttacgacaac agcttcacta gccgcaagat
    20101 ttggcagttc tccaggtaaa tccaagactg gaacaccttc tggcaagact gcattttttc
    20161 cacgaatgtt aaaaagttga acaccttcca ctcgcgcatc caccatcatc aactggaggg
    20221 cagtttggcc attccattgg ttgacagaca atttaaccgc taactctaga ttcttggttt
    20281 gagaaaactc tgtcgcccat ctgccttgac caaaggctac cacttcaaaa ctcgcctcac
    20341 ccttggaaat tttcagcttt agatgggcat tacctgcccc catagtacga gcactttcga
    20401 cctgaaaatt cttgatataa aaaataggtt tctgattatc cattccaaaa ggagctaaac
    20461 gttcaaaact tttgaccgtt tccaagctaa gtgcctccaa atccaactct tcatctaggt
    20521 ttaacttatt cttgccacca gcatctgcac ctttttcacg aacataatct tccaaaacct
    20581 gagataaatc tgagagttgc tcaacttcca gcgtcatacc cgctgcacct gcatgacctc
    20641 caaaggtgat gaagaggtct cgatggggat ccagagcttc aaaaatatcg accgcttcca
    20701 cactacgagc actgcccttg gcacgaccgt cttctatatt aagaacaatg actgtctgtc
    20761 ccaattcttc caataaacga ccagccacga ttcctagaac cccaggattc cagccttcct
    20821 tggccaagac ctgaaccttc ttctcaggat ccaccatggt cttggcttct tcatagatag
    20881 actgaacgat ttccttgcgc tcttcgtttt tctggtgaat cataagggca atctcatgcg
    20941 cttcttcatc atcaaatcca gtcaacaaat caatggcagg attgggatca tccaagcgac
    21001 ccaaggcatt caaacgagga gcaatctgga aaccaaccgt ttcttctgtt acttcgttgg
    21061 cagcaatccc agccatgtcc agcatttctt gcagaccaat gcgctgggta tgacccaaca
    21121 tttccagacc atattgaact aagatacgat tttcatccgt cagactcacc atatctgcaa
    21181 tagttccaat agcgaccaaa tcaagcaatt ccacttgcac ttcttctaac agggcacaag
    21241 ccaacttgaa agcaactcca caaccagcca aatatttaaa aggataatcc gcatctggat
    21301 gttcaggatg gacaatagca taagcatctg gcagggtttc aggcatggaa tgatggtctg
    21361 tcacaatgac atctactccc atagactgag ccaatgcaat agcctcatga ccagcaaccc
    21421 cattgtccac cgtcacaatc aaggaaatcc cttcttgctc gataaagtat ttataaacac
    21481 tagcattagg gccatagcca tcggtaaaac gatttggcag gtaaactcgg cactcagcac
    21541 caagttgttc caaactttcc ttcacaatag aagccgaagt catgccatcc gcatcatagt
    21601 ctccataaac aagaatattt tccccttctt caatagcctg acgaatccgc tccactgcct
    21661 tgtccatatc atggagcaga taagcatcat gtaagtcctc caaggaaggt tctaaaaact
    21721 tcttcagact ttcttggttc tgaatccctc tctcaaacaa taaccgagcc acctcaggac
    21781 ccagtccagc cttcttggct atctttgtaa aatccgcatc ttctacctgc agggcaaact
    21841 gccattcata agtaggtgtt atcaaaaaga catccactct ttctaagaat tctattgctt
    21901 cattataaca tgatttagac gttttctcta tccagattgc ttttttataa cattttatag
    21961 ta
//
LOCUS       DAVMBH010000033        21800 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVMBH010000033 DAVMBH010000000
VERSION     DAVMBH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21800
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.033"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            178..1668
                     /gene="lysS"
                     /locus_tag="VYP30_001433"
     CDS             178..1668
                     /gene="lysS"
                     /locus_tag="VYP30_001433"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1808414.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2293..3429
                     /gene="lctO"
                     /locus_tag="VYP30_001434"
     CDS             2293..3429
                     /gene="lctO"
                     /locus_tag="VYP30_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1808415.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      3681..3769
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            3984..4652
                     /locus_tag="VYP30_001435"
     CDS             3984..4652
                     /locus_tag="VYP30_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1808416.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            4889..5671
                     /gene="thiM"
                     /locus_tag="VYP30_001436"
     CDS             4889..5671
                     /gene="thiM"
                     /locus_tag="VYP30_001436"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1808417.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            5673..6302
                     /locus_tag="VYP30_001437"
     CDS             5673..6302
                     /locus_tag="VYP30_001437"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1808418.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKD
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      6511..6599
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6861..7421
                     /locus_tag="VYP30_001438"
     CDS             6861..7421
                     /locus_tag="VYP30_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1808419.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     VFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            7422..8807
                     /locus_tag="VYP30_001439"
     CDS             7422..8807
                     /locus_tag="VYP30_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808420.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQRCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVMLLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDSLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            8809..9459
                     /locus_tag="VYP30_001440"
     CDS             8809..9459
                     /locus_tag="VYP30_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1808421.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLTQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            9470..10162
                     /gene="tenA"
                     /locus_tag="VYP30_001441"
     CDS             9470..10162
                     /gene="tenA"
                     /locus_tag="VYP30_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1808422.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            10167..10691
                     /gene="thiW"
                     /locus_tag="VYP30_001442"
     CDS             10167..10691
                     /gene="thiW"
                     /locus_tag="VYP30_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1808423.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            10691..11494
                     /locus_tag="VYP30_001443"
     CDS             10691..11494
                     /locus_tag="VYP30_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1808424.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGITTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            11487..12119
                     /locus_tag="VYP30_001444"
     CDS             11487..12119
                     /locus_tag="VYP30_001444"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1808425.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVRLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLIGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(12328..13119)
                     /gene="thiD"
                     /locus_tag="VYP30_001445"
     CDS             complement(12328..13119)
                     /gene="thiD"
                     /locus_tag="VYP30_001445"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1808426.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVYKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(13203..13301)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13485..13880
                     /locus_tag="VYP30_001446"
     CDS             13485..13880
                     /locus_tag="VYP30_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1808427.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            13891..14262
                     /locus_tag="VYP30_001447"
     CDS             13891..14262
                     /locus_tag="VYP30_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1808428.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEIMPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            14272..16515
                     /locus_tag="VYP30_001448"
     CDS             14272..16515
                     /locus_tag="VYP30_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1808429.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            16722..18497
                     /gene="spxB"
                     /locus_tag="VYP30_001449"
     CDS             16722..18497
                     /gene="spxB"
                     /locus_tag="VYP30_001449"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1808430.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            18608..18955
                     /locus_tag="VYP30_001450"
     CDS             18608..18955
                     /locus_tag="VYP30_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1808431.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(19072..19313)
                     /locus_tag="VYP30_001451"
                     /pseudo
     CDS             complement(19072..19313)
                     /locus_tag="VYP30_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            19484..19765
                     /locus_tag="VYP30_001452"
     CDS             19484..19765
                     /locus_tag="VYP30_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1808432.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            19897..20841
                     /gene="manA"
                     /locus_tag="VYP30_001453"
     CDS             19897..20841
                     /gene="manA"
                     /locus_tag="VYP30_001453"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1808433.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDTLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLFSILAGQGQL
                     TVDGKNYPIQKGSHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(20881..>21800)
                     /locus_tag="VYP30_001454"
     CDS             complement(20881..>21800)
                     /locus_tag="VYP30_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1808434.1"
                     /translation="IISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPLLFI
                     IFVVIIGRSLSLSNAMEGVLYFLKPDFSKLTSAGLLYALRQSFFALSLGVTAMLTYAS
                     YLDKKTNLVQSRISIVAMNISVSIMAGLAIFQARSPFNIQSEGGPSLVFIVLPQLFDK
                     MPFGTIFYVLFLFATVTSSVVMLEINVDNITNQDNSKRAKWSVILGILTFVFGIPSAL
                     SYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALCLSLFTGYIFKKALAMEELHLDERA
                     WKQGLFQVWLFLLRFVIPIIIVVFIAQFM"
BASE COUNT         6498 a         4007 c         4820 g         6475 t
ORIGIN      
        1 ttggctatat cgctagtggg gcgggagata ctttcacttc tttccagtga ttttagcgtc
       61 aggttctttt tagtttttaa agattatccg tgaatttctt gcttatttat gataaaatgg
      121 gagtatcgca aaaaatgact catcgtattc aattttgagt aaaactagga ggatcccatg
      181 tctacagaac atatggaaga actaaatgac cagcagatcg ttcgccgtga aaaaatggct
      241 gcgctccgcg aacaaggaat cgatcctttc ggaaaacgtt ttgaacgtac tgcaaattca
      301 caagaattaa aagataaata tgccaacctc gataaagaac aattacacga taaaaacgaa
      361 acagctacta tcgcaggacg cttgataacc aaacgtggta aaggaaaagt tggttttgcc
      421 caccttcaag accgcgaagg ccagattcag atctacgttc gtaaggatgc tgtcggtgaa
      481 gaaaactacg aaatcttcaa aaaagcagat cttggtgact tccttggtgt cgaaggtgaa
      541 gtgatgcgta cggatatggg agaactctct atcaaggcaa cccacatcac acacttgtct
      601 aaggctcttc gtcctcttcc tgagaaattc catggtttga cagacgttga aacaatttac
      661 cgtaaacgtt accttgactt gatttctaat cgtgaaagct ttgaacgttt tgtcactcgt
      721 tcaaaaatca tctctgaaat ccgtcgttac cttgaccaaa aaggattcct tgaagtggaa
      781 acacctgttc ttcacaacga agctggtggt gctgctgccc gtccatttat cacccaccac
      841 aatgcccaaa acattgacat ggtgcttcgt atcgcgactg aacttcactt aaaacgcctt
      901 atcgtgggtg gtatggaacg tgtctatgaa attggccgta tcttccgtaa cgaaggaatg
      961 gacgctactc ataaccctga gtttacttct atcgaagttt accaagctta tgcagacttc
     1021 caagacatca tggacttgac ggaaggcatt atccaacacg ctgctaaatc agttaagggc
     1081 gatggcccag ttaactacca aggtactgaa atcaagatta acgaaccatt taagcgtgtt
     1141 catatggtgg atgctatcag agaaattact ggtgtcgatt tctggcaaga catgactttg
     1201 gaagaagcta aagctatcgc tgctgagaag aaagttccag ttgagaaaca ctacactgag
     1261 gttggtcaca tcatcaatgc cttctttgaa gagtttgttg aagaaacttt aatccaacca
     1321 acctttgtct atggacatcc agtagctgta tctccactcg ctaagaaaaa tcctgaagac
     1381 caacgcttta ctgaccgttt cgagctcttt atcatgacta aggagtacgg taatgccttt
     1441 actgagctca acgacccaat cgaccaactt agccgttttg aagcccaagc taaagccaaa
     1501 gaacttggtg atgatgaagc gacaggaatc gactatgact acattgaagc ccttgaatac
     1561 ggtatgccac caacaggtgg tttgggaatc ggtatcgacc gtctctgcat gctcctcact
     1621 gatacaacaa ctatccgtga tgtattgctc ttcccaacaa tgaaataaat tcttatcctc
     1681 tggctcttat caggggattt tttgattcaa aaagagactg aatttaagga gaaaatgaag
     1741 tgtagtatat tgaagttgaa atagtacact ttgatttcta agacattctt agaaattggt
     1801 ttaaattccc taagcaattt gtgcatgttt tatttcattt tacgatagta cgctgaaact
     1861 gttcaaaaag tactagaaat tgacttggat tccccaattg atttgttcag attcactata
     1921 aataaaaaat taataagtgg gataggaagt tagcgtcaac taggatagta tcttgcttaa
     1981 acagtatata tgggactgat ataagtccat aggtcctatt agaggatgtt ctggtgtctt
     2041 attcacttgt ttttttatag tattagtaga tagaatcagc aaataaaaaa gtagtttaaa
     2101 tgcctggcag caaaaaatct caacgattca cttaatatag actaaagttt agagtttaag
     2161 gaaagtaggg ctagtatatt gtatgaaaaa ataagatggt ttttaagcaa aactcttgaa
     2221 aatgattgaa aaaagagtta ttatagttgt atagtaaaaa gcaaacgctt acttaattaa
     2281 gggggacagt ttatgtcata caaaacaagc aatgcagaag gtcatgtaga tttcatcaat
     2341 acctatgatt tggagccaat ggcgcaacaa gttattccta aagcagcatt tggctatatc
     2401 gctagtgggg cggaagatac tttcactttg agagagaata tccgcgcctt taaccacaaa
     2461 ctcatcgttc ctcatacact ttgcgatgtt gaaaatccaa gtacagagat tgaatttgca
     2521 ggtgaaaaac tatcttcacc aatcattatg gcgcctgttg cggctcataa attggcaaat
     2581 gaacaggggg aagtggcgac tgcgcgtggt gtgcatgagt ttggttctct ttatacaacc
     2641 agctcttact ctactgttga ccttccagag atttctgaag cccttcaagg gaccccccat
     2701 tggttccaat tttactttag taaggatgac ggtatcaacc gccacatcat ggaccgtgtg
     2761 aaggctgaag gttataaagc gattgtcttg acggcagatg ctactgtagg ggggaatcgt
     2821 gaagtggata agcgtaatgg ttttgtcttc ccagttggca tgccgattgt tgaagaatac
     2881 ctgccagaag gtgctggtaa atcaatggac tttgtttaca aatcagctaa acaacgcttg
     2941 tctccacgcg atgtagaatt tatcgctgaa tactctggtc ttcctgtgta tgtcaaggga
     3001 ccacaatgcc gtgaggacgt tgaacgttcg cttgctgcag gagcttctgg tatctgggta
     3061 accaaccacg gtggtcgtca aatcgacggt ggaccagctg cctttgactc gcttcaagaa
     3121 gtggcagaag cagttgatag acgtgtgccg attgtctttg actctggtgt tcgtcgtggt
     3181 caacacgtct ttaaagcctt ggcttcagga gcagacttgg tagctattgg tcgccctgtt
     3241 atttatggct tggctctcgg tggtagtgtc ggtgtgcgtc aagtctttga acacttgaat
     3301 gcggaattga agacagttat gcaattgtct ggagctcaga ccattgaaga tgtcaaacac
     3361 tttaagctcc gtcacaatcc atacaaccca accttcccag ttgaccctcg tgacttaaaa
     3421 ttgtattgat aaaacagatt gcctccactg aatgtggagg tttttcttcg tgtattggaa
     3481 gaataaattg ctatcgaaaa ctatagtaaa atgaaataag aataggacaa atcaatcagg
     3541 acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
     3601 ctactatata aagatatttt tcggtcaaat atcttgctag ggctttcatt ttttgctata
     3661 ctggttcagt aattaaataa tagagacatt tggggtgctt taggctgaga taatacccat
     3721 tgaacctgat acagttaaga ctggcgaagg gaaatgtgaa acgttttttc gtatggcgaa
     3781 atgaacgatc taatcttgta agtcaactct aattcttgat tgtaattgga gttttttgtt
     3841 tatataaact ggataggctt gtttagttag ctctctgtaa atgctctcga tgtgctttaa
     3901 aaggatcaag tggaattacg attttgcttg atatttcttg ctgttttatt aattactaac
     3961 aagtaaagag aggagaagta aatatggaaa cacaagacta tgcatttcag ccaggtttga
     4021 ctgttggaga attattaaaa agcagtcaga aggattggca ggctgcaatc aatcatcgtt
     4081 ttgttaagga actttttgcg gggacaattg agaataaggt cttaaaggac tatctgattc
     4141 aagattatca cttctttgat gccttcttat ccatgctggg tgcctgcgta gctcacgcag
     4201 ataaacttga atccaagctt cgttttgcca agcaactagg ctttcttgaa gcagatgaag
     4261 atggttattt ccaaaaggct tttaaagagt taaaagtagc agagaatgac tatctagaag
     4321 tgactttgca ccctgtaaca aaagcctttc aggatctaat gtattcggcg gtggcttcat
     4381 cagactatgc ccatcttttg gtcatgctgg tcattgcaga aggtctctat ttagactggg
     4441 gttctaaaga tttggcttta cctgaagtct atattcattc ggaatggatc aatctccaca
     4501 gaggtccttt ctttgcagag tgggttcaat ttctggttga cgaactcaat cgtgtcggta
     4561 aaaatcgaga agatttgaca gaacttcagc aacgctggaa tcaagcagtc gctttagaat
     4621 tagctttttt tgatattggt tacgatgtct agagaaggct catgatattt acaaatttga
     4681 tgaggtaaga ctcttcgaaa atctcttcaa accacgtcag ttctatccac aacctcaaaa
     4741 cagtgttttg agcaacctgc gattagcctc ctagtttgct ctttgatttt cattgagtat
     4801 aaatcattca atgtaaatga aaaaaattct caactaaaga taaatcgaaa ttagtagatc
     4861 gtataaagtg aaaaggaagg atttcaatat gacaagttta aaattattaa aagaaaaagc
     4921 acctttggtc atttgcatca ccaatgatgt agtaaaaaat ttcacagcaa atggattagt
     4981 agcactgggc gcctcaccag ccatgagtga gtttccagca gatttagagg acttattaaa
     5041 gtatgctggt ggtttattaa taaacatagg aacattgaca gatgaaaatt ggaaattata
     5101 ccaagctgct ctgaaaattg cagagaaata taatgtccca gcagttttag atcctgtagc
     5161 ctgtggagca ggagaatata gaaaaaaagt agcagatgat ctaatcaaca attacaaact
     5221 agctgcgatt agggggaatg ctggagagat tgcctcttta gtaggaatag atgtggcatc
     5281 taaaggagta gatagtgcgg gagtagataa tattgacgag attgctctag cagcaaatga
     5341 gaagttcaat attccaatag tagtaacagg tgaagtggat gccattgctg ttaatggaga
     5401 agtggtaacg attcataatg gtagtgctat gatgccgaaa gtcattggga caggatgctt
     5461 attaggagct gtagtagcaa gctttatcgg actagaaaaa ggtcaagaat tgaaatcatt
     5521 agaaacagca atgttagttt acaatatcgc tggagaaatg gcagaaaaac gtccaaatgg
     5581 acatcttcct gggacattta aagttgaatt tataaatgcc ttatacgaga ttacagatga
     5641 agatgtaaag gaattcaaaa gagtgaagta agatgtttca taaagaatta ctaaaactat
     5701 attttatttg tggaacgact acttgccaag gaaaaaatct atatacagtc gttgaggaag
     5761 ccttaaaagg tggtataacc ttatttcaat ttcgagaaaa agatgagggt gctttagaag
     5821 gcttagaaaa acttgagcta gctatccaaa ttaaagaact ttgtaaaaaa tacaatgttc
     5881 catttatcgt taatgacgat atagatttag caatggaaat tgacgccgat ggcgtacatg
     5941 taggtcaaga tgatattggt gttgatgaaa ttagaaaatt gatgccagat aaaataattg
     6001 gtctttctat aagaaacgaa gaagaatttc aacaatcaaa agttgaatat gtagattatg
     6061 taggtgttgg gcctgtattt gatacccagt caaaagatga tgctggtggt gctataggtt
     6121 atgaaggtct tgaattgatg agaaaactat tgccacaaat gcctttagtt gcaattggtg
     6181 ggatacagac gaaacatatt aaagacatta taaagaccaa tatggatggc gtttcaatca
     6241 tttcggcaat atcgtatgca aaaaatatag aaaaaactgt tcgggaaatg agtgagcaat
     6301 agatatctat ccttggattc taagtaagta ggattttcct tttttaaaaa gctatgtcta
     6361 gattcagctt gaatggttaa ttcatcaaac aggtcatttg ttttttgcaa aagaaagatc
     6421 tgctgtcttt gtgagtgcaa ggctgtattt ccagttcaat ttcttgaact agtataaaat
     6481 gtgtgttata ataatcacat aattaaataa taaaggcatt tggggtgctt taggctgaga
     6541 tgatacccat tgaacctgat acagttaaga ctggcgaagg gaaatgtgaa atgttttttt
     6601 cgtatgtcga aaagaactgt ctaatcttgt aagctgaact ctaattcgta tctgtaatta
     6661 gagttttttc ttttacgaaa ctggatgaag atgatatagt agattgaaat aagatgcgaa
     6721 caaatcaatt agaaaattca aattaatttc tagaaatatt ttagcattct tgtgtactgt
     6781 tctaaattca gtctgctata caaagtattt aggtcggtct tcttgagtgc cccacttttc
     6841 tttaaaaaaa ggagtttttt atgttgaaaa aatggcagtt aaaagatgtt atcttgcttg
     6901 ctttcttgtc tatctttttt ggtggggttt tcgttggttc aggatatgtg tataatattc
     6961 tcagtctact cttaacacct cttggtttgc aggtctttgc caatgaaatc ctcttcggtc
     7021 tctggtgtat ggctgcgccc attgctgcca tctttgttcc gagagtcgga agtgcaacga
     7081 ttggagaagt gctagctgcg cttgctgaag tcctttatgg tagccaattt ggtctaggag
     7141 ctcttttgtc tggcttggtt caaggtttgg gaagtgaatt tggttttatc gtaactaaga
     7201 atcgctatga aagttggctc tctctaactg ctaatagtat tgggattacg cttgttagct
     7261 ttgtctatga atacattaag ttaggttact acgccttttc ccttccgttt gtcctttcct
     7321 tacttgtggt acgttttatt tctgtttatt tcttctgtac catcttggtt cgtgccattg
     7381 tcaaactcta tcatcagttt gcaactggag gaaaagcata gatgggtctg gaactacgag
     7441 cgattcagtc cccaatcttc tctgagccgt ttgattttac ttttcatgtg caagccttta
     7501 ccttgttagt tgggagtagt gggtctggaa aatcgagcct ctttcaaatg attgcccaag
     7561 ttagttctct tccctatagc ggtcaagtcc tgatagatgg gagtgaggtc agtcagcttt
     7621 ctatcgtcga acgtgtccag aaggttggca ttctctttca aaatcccaat catcaattta
     7681 ccatggagaa cttgtttgag gagctgattt tcaccttgga gaatatcggc tatcaccttc
     7741 aggaaattga ttctaaaata gcagaggttg tccagcgatg tcgttgcgag gcaatcttac
     7801 accgtcccat tcatcaccta tcaggtgggg aaaagcaaaa agcagcgctg gctgtcctct
     7861 ttgccatgaa tcctagggta tatctcttgg atgagccctt cgcttccatt gaccgcaaga
     7921 gcagaatcga gatattggag attctaaaag agttggctct tgatgggaag acagttattt
     7981 tgtgcgacca tgatttatct gactataaag cctatatcga ccatatggtt gagctaagag
     8041 acggaaaact aagggaagtg tttcaaatcc cttcctatga gatgacacag gttgcttcaa
     8101 aggaagttgc ttctagcccg gaactattcc atatgaaccg tgtgactggt gagcttggta
     8161 atcgccccct cttttcaatt gctgatttca cattctatca agggatttcc tgtatcctgg
     8221 gtgacaatgg tgtcgggaaa tcaaccctct ttcggtctat tcttcaattt caaaagtata
     8281 aggggagcat tacttggaag ggttcggtcc tgaaaaagaa aaagagtttg tatcgtgatc
     8341 tgactggtgt tgttcaggaa gctgagaagc agtttatccg agtcagtctg cgagaggagc
     8401 ttcaattaga tggacctgat tctgaaagaa atcagcggat ttttcaagct ttacgatatt
     8461 ttgatttgga gcaggcagtc gataagagtc cctatcaatt aagtggtggt cagcaaaaaa
     8521 ttcttcagct cttgaccatc ttgaccagta aggcttccgt gatgttgcta gatgaacctt
     8581 ttgcaggttt ggatgataga gcctgccatt atttttgcaa gtggattgtg gaggagagga
     8641 atcaaggaag aagttttctg ctcattagtc atcgtttaga ctctttgatt tctgtggttg
     8701 attattggat tgagatgact agtcagggtc ttcggcatgt gaaagaagtg accattacca
     8761 aaccacttac atctcagagt agcaataccc aaggggaggt gagatagtat ggtcaaagta
     8821 gcaacccaga caccgattat cagtctcttc ttgctgattt tatccttgga aacatctttc
     8881 attccttcga ttgctctgaa tctttcggta gtcgcatttt gtattctctt tatgctctat
     8941 taccgtcgat ttaaaatgtt agcttggatg atcatacttg ccattttacc atcttttgcc
     9001 aactactggg cagttcagtt acacggagat gcttcacagg cagtcatgct tggaacgagg
     9061 gcctttgtga cagtttgtat cggccttgtc tttgtttcct ctatttcact aaaagagctt
     9121 ctcttgtact tgactcaaaa ggggctatca cgctcttggt cctatgcctt gattgtggta
     9181 ttcaattcct ttcctctcat tcagcaagaa atcaagtccc tcaaagaagc ttgcctatta
     9241 cgtggtcaag aactgcattt ttggtcgccc ttgatttaca gtaaggttct gatgacagtc
     9301 tttaggtggc gccatcttta cctgagagct ctgtctgctc atggatatga cgaacatgca
     9361 cagttgaaga atagctatcg gactttttat attcctaaaa aaacaaaatt aatctacctg
     9421 cttttctttt tattgcttca aaccagtcta tttttataaa ggagttatta tggaatttac
     9481 agatattgcg atggaattat ccaagaaagc ttggcaggct tcctttcatc atccctttat
     9541 tttacaatta caagagggga atttagaacc tgccattttc cgctattacc tgattcagga
     9601 tgcctactat ctgaaggcct tctcagaaat ctatcatctt ttggctgata agacttcaaa
     9661 ccaagagatg aaaagactct tgaaacaaaa tgctcagggt ttagtggagg gtgagttatt
     9721 tattcgccaa caatttttca aggaaatgga aatcagcgac caggaaatgg agcaacatcc
     9781 aattgctcca acctgttatc attacatttc tcatatttat aggcaatttg cagaaccgaa
     9841 cttagccatc gcttttgcaa gcttgcttcc ttgtccttgg ttataccatg atataggcaa
     9901 atcacttaat cttaaaccat caccaaatcc tctctatcaa caatggattg aaacttatat
     9961 tacggatgag ttagagcaac agatcagaga ggagggagca ctggtcaatc agctctatcg
    10021 agaaagtgat gagacagata agcaaaaaat gctagatgcc ttccacatca gtgttcatat
    10081 ggaagccaag ttttgggaga tggcttacca acaccagaca tggaagagcg atttacagtc
    10141 tttagaaaaa ggagaagaat agaaacatga gaaagcacca actacaagtt cacaaattga
    10201 ccattttatc tatgatgatt gcccttgatg tagtccttac acctatcttt cggattgagg
    10261 gaatggcacc gatgtccagt gtagtcaata ttctagcggg aatcatgatg ggacctgttt
    10321 atgccttggc tatggctaca gtgacagcct ttatccgtat gacgactcaa gggattccgc
    10381 ctttagctct cacaggagcg acttttggag cccttctagc aggtctcttt tataagtacg
    10441 gtcgaaaatt ttacttttct gccttgggag aaattgtggg aacaggtatt attggttcta
    10501 ttgtttccta tcctgttatg gtgctcttta caggatcggc tgctaagctt agttggttta
    10561 tctacacgcc tcgatttttc ggagcaacct tgattggtac agcgatttcc tttattgcat
    10621 ttagattttt aatcaagcag gaattcttta aaaaagtgca aggatatttc tttgctgaaa
    10681 ggatagaatg atgcaggcat tgacaaatcc ttttcctata ggctctagtt ccctcattca
    10741 ctgtatgacc aatgagattt cttgtgagat gctggcaaat gggattttgg ctctgggatg
    10801 caaacctgtc atggcagatg atccccgtga agttcttgat tttactaagc aaagccaggc
    10861 tctcttcatc aatttggggc atttgtcagc tgagaaggaa aaagcaatcc gcatggcagc
    10921 tttgtatgca aaccaatctt ctctcccgat ggtagtagat gcggttggca taacgacttc
    10981 atccattcgt aagagcttag ttaaagacct tttagactat agacctacgg tccttaaagg
    11041 aaacatgtca gaaattcgaa gtcttgttgg attaaagcat cacggcgttg gggtcgatgc
    11101 gagtgctaaa gatcaagaaa cggaggattt gcttcaagtc ttgaaagact ggtgtcagac
    11161 ctatcctggt atgtcattct tagtcacagg tcccaaggac cttattgttt cggagaatca
    11221 agttgctgta cttgagaatg gctgtactga attagactgg ataacaggga caggagactt
    11281 ggttggagcc ttaacagctg tttttctcag ccaaggaaag actggttttg aagcttcttg
    11341 cttagcagtc tcttatctca atatcgctgc tgagaaaata gttgttcaag gaatgggatt
    11401 ggaagaattt cgttaccaag tactcaatca gctttcgctc ctaagaagag atgaaaattg
    11461 gctagatacc atcaaaggag aggtttatga atagagaagc gcttagacta tatctggtaa
    11521 ccaatcgcta tcaagattcc gtggaaagct ttcttgcaaa agttgagacg gcctgccgtt
    11581 caggggttac catagtccaa ttgcgagaaa aaaatctcac aaccaatcaa tattatcaac
    11641 tggcaaaaca agtcaaggaa ataacagatg cctatcaggt ccgcttgata atcgatgatc
    11701 ggttggatgt ttgtcttgcg gttgatgctg ctggtctgca tattggagat gacgaactcc
    11761 cagtttcggt agctcgcaaa gtcttgggtc ctgaaaaaat cctcggtgtc accgctaaaa
    11821 cggttaaaag agctctggaa gcggagaaat caggtgcaga ttacttgggg acaggagcca
    11881 tttttccgac aaccaccaag gaaaatgcac ccatcaccct gatttcaacc ttgaaaacaa
    11941 tttgtcaaac ggttgccatt ccagtagttg ctattggcgg cttgacatca gagaatattg
    12001 accaacttat cggcacgggt atagctggtg tagctgttgt acgtgatttg atgcaagcag
    12061 aagatattga ggcaaaaacg caagcctttt taacaaagtt gcatgacatt ctttcctaat
    12121 taatactcaa tgaaaatcaa agagtaaact agaaagctag tcgcaggttg ctcaaagtac
    12181 tgccttgagg ttttagataa gactgacgaa gtcagctcaa aacagtgttt tgaggttgca
    12241 gatggaagct gacgtagttt gaagagattt tcgaagggta taaaaactct ctaattccct
    12301 taaagtggga actagagagt ttttttctta atctttaaaa gttgtatggt tgactggacc
    12361 agaaccatga ccgagttgag gggcatcttg aatagctttt gtgataaagg ccttggcctt
    12421 ataaactgcc tggtaaagac tcttgccctt ggctaattca gcagtaatca ctgcagcaaa
    12481 ggtacatcca gtaccatggg tgtgacaggt ttgaattcgt gggctttccc agacaaattg
    12541 ttcattcttg gtaaagagga aatctttagc accacctttg agatgtccgc ctttgataac
    12601 cacagactga ggaccaaatt cttttaaaat caggcgacca gcacgctgca tgtcttcggg
    12661 gtcatggatt gaaaaaccaa caatctcttc tgcttcagga agatttggcg taataatagt
    12721 tgctagaggt agtaagtttg ttttgagata gtctctagca cttgagtcaa tcaaggcatc
    12781 tccacttgta gcaaccataa caggatcaag gacataggga caatccagtt ttttaagata
    12841 gggttggatg atttccatga tttcagtagt agccaacatt ccagttttta cagcctgagg
    12901 tggaatatca gaaaagacac tctccaattg ggctttcaac atttgaggag aaacgtgctc
    12961 gattagctga acacctctgg tattttgagc gacaagactg gttacaacag ccattccata
    13021 gacatctctc gcttggaatg actttaaatc tgccataatg ccagcaccac cactagggtc
    13081 agtccctgca atggtcaaag caacgggtaa ataagtcatc taaaacctcc caaccaactg
    13141 aagtttgtat tcttaagaac aagctagtct gttttagaaa ggcaatagaa gactgctagt
    13201 ccccattatc atttccactt ccatcagcta gcattatcta gattgagtca gagggatcta
    13261 acagtcgtta atctcagctt tacgcacccc tagtggttgt tttctttttt ctttagtata
    13321 gcatattttt attgtttata tagtaatatt tgactgcaaa tcgtttttca aatgattaaa
    13381 attctatttt tcgaagaaaa tattatttct ataattgaca aatgtagatt ttaagagtat
    13441 actgatgagt gtaattgaca aatgtagatt ttggaggtat ggtaatgcag atttcagatg
    13501 cagaatggca ggtcatgaag attatttgga tgcaggggga gcagaccagt acagatttga
    13561 ttagggtttt ggcagagcgg tttgactggt ccaagtccac ggttcagaca cttttggctc
    13621 gtctggttga gaaagagtgt ttgactcgga aaaaagaagg caagtccttt gtttattcag
    13681 cccttttaac tctagaccaa agtcgggatt tacttgtcca agatatcaaa gacaaggttt
    13741 gttcccgtag gattaggaat ttgttggctg acttgattgt agaatgtgaa tttactcaga
    13801 ctgacttgga agacttggaa gctgtgattt cagagaagaa atcaagtgct gtaacagaag
    13861 taagatgtaa ttgtatgtaa aggagacgtc atgttaaata gtattgtaac cattatttgt
    13921 attgccctta tcgcatttat cttgttttgg tttttcaaaa agcctgaaaa atctggacaa
    13981 aaagcccagc aaaaaaacgg ataccaagag attcgagtgg aagtcatggg aggctatact
    14041 cctgagttga ttgtcctaaa gaaatcagtg ccagcacgca ttgtctttga ccgcaaggat
    14101 ccttcaccat gtctggatca aattgttttt ccagattttg gtgtacatgc gaacctgcca
    14161 atgggggaag agtatgtagt ggaaatcatg cctgaacagg ctggagagtt tggctttgct
    14221 tgtggtatga acatgatgca cggcaagatg attgtagagt aggtggagac tatgacagaa
    14281 attgtgaaag caagcttaga aaatggcatt caaaaaatcc gtatccgagc tgaaaaaggc
    14341 tatcatccag cccatatcca gcttcaaaag ggaattccag ctgagattac ctttcatcgt
    14401 gctactcctt caaactgtta taaggaaatt ctgtttgaag aagaaggtat cttggaacca
    14461 atcggcgtag atgaggagaa agtcattcgt tttacgcctc aagaattagg gcgacatgaa
    14521 ttttcttgtg gcatgaagat gcaaaaggga agctatacag tcgttgagaa gactcgaaaa
    14581 tctctatctc tcctgcaacg tttttggatt actagtatct ttactgtgcc tcttgtgatt
    14641 ctcatgattg ggatgttggc aggtagcatt agtcatcaag tcatgcattg gggaaccttt
    14701 ttagcaacaa cgcctattat gttagttgca ggtaagccat atatccagag tgcttgggcc
    14761 agttttaaaa agcacaatgc caacatggat accttggttg cgctgggaac tctagtggct
    14821 tatttctata gcctagttgc tctctttgct ggtctccctg tttacttcga aagtgctgga
    14881 tttatcctct ttttcgttct tttgggagca gtttttgagg aaaaaatgag aaaaaatacg
    14941 tcccaagctg tggagaaatt actggacttg caagctaaaa ccgcagaagt cttgagtgat
    15001 gatagttatg tccaagttcc tttggaacaa gtcaaggtag gcgacctgat tcgagtgcgt
    15061 cccggtgaaa agattgctgt tgatggtgtc gtagtagaag gtgtctctag tattgacgaa
    15121 tccatggtga caggtgagag tctgcctgtg gacaagacag ttggagatac tgtcattggc
    15181 tcaaccatca atcatagtgg aacgcttgtc tttagagcag aaaaagttgg ctcagagact
    15241 gttttggctc agattgtgga ttttgtgaag aaagctcaga caagtcgtgc gccgattcag
    15301 gacttgacgg ataagatttc agggattttt gtcccagtag ttgtcatttt aggaatcatg
    15361 accttttggg tttggttcgt cttgctcagg gatagtgtgg tcgtgcttgg agctagcttt
    15421 gtgtcctctc ttctctacgg agtggcggtt ttgattatcg cctgtccttg tgccttggga
    15481 cttgcaacac cgacagccct tatggtgggg acaggacgta gtgccaagat gggggttctc
    15541 ctcaaaaatg gaactgtctt acaggaaatc cagaaagttc aaactcttgt ctttgataag
    15601 accgggactt tgacggaagg gaaacctgtg gtaacagata tcatcggtga cgaagtagaa
    15661 gtgtttggat tggcagcctc cttggaagat gcttctcaac acccactggc tgaggctatc
    15721 gttaagcgag cgagtgaagc tggacttgag tttcaaactg ttgaaaattt tcaggccttg
    15781 cacgggaaag gtgtttcagg gcgaatcaat ggaaaacaag ttttacttgg aaatgctaaa
    15841 atgctggatg gcatggatat ttctaatact tatcaagata aactagaaga actagaaaaa
    15901 gaagctaaga cagttgtgtt tttagctgtt gacaatgaaa tcaaaggctt gcttgctttg
    15961 caagatattc ctaaggaaaa tgctaagcta gccatcagtc agctaaaaaa acgtggtctc
    16021 cgaacagtca tgctgacagg agacaatgct ggtgtggcgc gtgctattgc agatcaaatc
    16081 ggaattgaag aggtcattgc aggcgtcttg ccagaagaaa aagcccatga aatccataaa
    16141 ctgcaacagt cagggaaagt agcctttgtt ggggacggta tcaatgacgc tcctgccctt
    16201 agtgtagcag atgtggggat tgctatggga gctggaacag atatcgccat cgagtcagca
    16261 gatttggtgt tgacaaccaa taatctttta ggagtggttc gtgcctttga tatgagtaag
    16321 aaaacctttc atcgaattct actcaatctt ttctgggctt ttatctacaa tgttgtcgga
    16381 attccgattg cagcaggagt cttttcaggt gttggactgg ctctcaaccc agaattggca
    16441 ggtctagcca tggcctttag ttctgtatct gttctgacca gttcccttct gttaaatttt
    16501 agtaaaatag actaaaagta atgactagat ttctttgtta taaaacagaa atgacagaac
    16561 tttaaaaact gtattagaat agagaataga gagttttgag cagattttta gaaaagtcag
    16621 cataaatatg atacagtgga atagtaaaaa tttggagaac gtttccaatt ctatgtaatc
    16681 gtattctcca aatctaaaaa aattgaagga gagttatcat tatgactcaa gggaaaatta
    16741 ctgcatctgc agcaatgctt aacgtattga aaacatgggg cgtagataca atctacggta
    16801 tcccatcagg aacactcagc tcattgatgg acgctttggc tgaagacaaa gatatccgct
    16861 tcttacaagt tcgccacgaa gagacaggtg ctcttgcagc ggttatgcaa gctaaattcg
    16921 gcggctcaat cggggttgca gttggttcag gtggtccagg tgcgactcac ttgattaacg
    16981 gtgtttacga tgcagctatg gataacactc cattcctagc gatccttgga tcacgtccag
    17041 ttaacgaatt gaacatggat gctttccaag agcttaacca aaacccaatg tacaacggta
    17101 tcgctgttta caacaaacgt gtagcttacg ctgagcaatt gccaaaagta attgacgaag
    17161 cctgccgtgc tgcaatttct aaaaaaggtc cagctgttgt tgaaattcca gtaaacttcg
    17221 gtttccaaga aatcgacgaa aactcatact acggttcagg ttcatacgaa cgctcattca
    17281 tcgctcctgc tttgaacgaa gttgaaatcg acaaagctgt tgaaatcttg aacaatgctg
    17341 aacgcccagt tatctatgct ggatttggtg gtgttaaagc tggtgaagtg attactgaat
    17401 tgtcacgtaa aatcaaagca ccaatcatca caactggtaa aaactttgaa gctttcgaat
    17461 ggaactatga aggtttgaca ggttctgctt atcgtgttgg ttggaaacca gccaacgaag
    17521 tggtctttga agcagacaca gttcttttcc ttggttcaaa cttcccattt gctgaagttt
    17581 acgaagcatt caagaacact gaaaaattca tccaagttga tatcgaccct tacaaacttg
    17641 gtaaacgtca tgcccttgac gcttcaatcc ttggtgatgc tggtcaagca gctaaagcta
    17701 tccttgacaa agtaaaccca gttgaatcaa ctccatggtg gcgtgcaaac gttaagaaca
    17761 accaaaactg gcgtgattac atgaacaaac tcgaaggtaa aactgagggt gaattgcaat
    17821 tgtatcaagt ttacaatgca atcaacaaac atgctgatca agacgctatc tactcaatcg
    17881 acgtaggtaa cactactcaa acatctactc gtcaccttca catgacacct aagaacatgt
    17941 ggcgtacatc tccactcttt gcgacaatgg gtattgccct tcctggtggt atcgctgcta
    18001 agaaagacaa tccagatcgc caagtatgga acatcatggg tgacggagca ttcaacatgt
    18061 gctacccaga cgttatcaca aacgttcaat acgaccttcc agttatcaac cttgtcttct
    18121 caaatgctga gtacggcttc atcaagaaca aatacgaaga tacaaacaaa cacttgtttg
    18181 gtgtagactt cacaaacgct gactacgcta aaattgcgga agctcaagga gctgttggat
    18241 tcacagttga ccgtatcgaa gacatcgatg cagttgttgc agaagctgtt aaattgaaca
    18301 aagaaggtaa aactgttgtc atcgatgctc gcatcactca acaccgtcca cttccagtag
    18361 aagtacttga attggatcca aaacttcact cagaagaagc tatcaaagcc ttcaaggaaa
    18421 aatacgaagc agaagaactc gtaccattcc gtctcttctt ggaagaagaa ggattgcaat
    18481 cacgcgcaat taaataattc ctctcgccga aaatcaaata tgaaacttgt agactttatt
    18541 ctttgatttt catagagcag aactttaaaa gatcggagca atccggtctt tttatggagg
    18601 agagtaaatg aatttaaatc aattagatat tatcgtttca aatgttcccc aagtctgtgc
    18661 tgacttggag catatcttgg ataaaaaggc agattatgct gatgatggtt ttgctcagtt
    18721 tacgattggt agtcactgcc ttatgttgtc acaaaatcat ttggttcctt tggaaaactt
    18781 tcagtcagga atcattattc atatcgaggt tgaggatgta gaccagaact acaaacggtt
    18841 gaacgagctt ggtataaagg ttttacacgg accaactgta accgattggg gaacagagtc
    18901 cttattagtt caaggacctg ctggtctagt gcttgatttt tatcgtatga aataggtcgc
    18961 gtagtcattt gacgttaacc ttagctattt ttaaaataga aattgagaat atgaactatt
    19021 gaaagatcgg agcaatccgg tctttttata taaagaaatt gcatataata ctcatctgct
    19081 ttcaaaaagt attctagtcc atctctgatt aacgatggac tttatcacct ccttctccag
    19141 tccttgtatg acatcttgga gttgattcat gacatcttcc aaagttcgaa aggctttatt
    19201 cttaaatcca cgtttatgaa tctctttcca cacttgttcg atgggttcat ctctggtgtg
    19261 tatggaggaa taaatgcaaa accaatatta gtcggagtct ttataagatt tgcccatcag
    19321 acgaaataga atgatttgaa ggcatttatg atatttagct gtacgagagt ctttaaaaag
    19381 tgttttgatg gtttggattt cttctttagt tgatttcata tcactattat ataatgcttt
    19441 ttgattttag tatagtatta tcgtagaaaa tggactcggt gctatggata caccggatga
    19501 gaatggttat gtagcagatg actaccggat tacttactta gaggcccaca tcaaggccat
    19561 gcgagatgcc atttacaaag acggggttga cttgcttggt tatacgacat ggggctgtat
    19621 cgattcggtt tcagctggca caggggaaat gaataagcgc tatggcttta tctatgtaga
    19681 tcgagataat gtaggaaatg ggactctcaa acgtagcaag aagaagtcct tctattggta
    19741 catgtcattt atagcaatgg tgtaagcatc gagtagagca catttgttta ctatttttat
    19801 aaaatcttct ccctgcttta taagatgtaa aaaagagttc aaatggaact ctttttttgc
    19861 tataatgagg ggagaaaaat cagacaggag attaagatgt cagaaccatt atttttacaa
    19921 tcagttatgc aagaaaaaat ctggggtggt accaagctac gtgatgagtt tggctacgac
    19981 atcccaagtg aaaaagtcgg agagtactgg gctatctcag ctcatctaaa tggtgtttct
    20041 aaagttgcca atggtcgtta cgagggaaca gatcttgcta ctttgtatgc ggaacaccgt
    20101 gaattatttg gcaatcgtcc tgagcctgta tttccgcttt tgactaagat tttggatgct
    20161 aacgactggc tcagcgttca agttcaccca gacgatgctt atggactaga gcatgaaggc
    20221 gaacttggaa aaacagaatg ctggtacatc atcgctgcgg atgaaggttc agagattatc
    20281 tacggccaca atgccaagtc aaaagaagaa ctccgccagc aaatcgagga caagaactgg
    20341 gataccttgc ttaccaaagt ccctgtcaag gctggagatt tcttctatgt accaagtggc
    20401 accatgcatg ctatcggtac tggcatcttg attcttgaaa cccaacagtc tagtgataca
    20461 acttaccgcg tctatgactt tgaccgaaag gacgataagg gcaacttgcg tgaacttcac
    20521 cttgaaaaat ccatcgatgt tttgaacatt ggcgagccag caaatagccg tcctgtaact
    20581 gttaaagcag ataatttgcg ttccacttta cttgtttcta atgatttctt cgcagtttac
    20641 aagtgggaaa tcactggaaa agttgatttt gagaagacag ctgattacag tttgtttagt
    20701 attttagctg gccaaggtca actgactgtt gatggaaaaa actatccaat ccaaaaaggg
    20761 agccacttta tcctaccaag tgatgttgaa tcttggactt tagaagggca agatttagaa
    20821 ttaattgtta gtcatccata aaaaagaaag ggcctgagtt cattactcaa gtccttttga
    20881 ttacataaat tgggcgatga agaccacgat gatgattgga atgacgaaac gaagaaggaa
    20941 gagccagact tggaacagtc cttgtttcca tgctctttca tcgagatgga gttcctccat
    21001 tgcaagagcc tttttaaaga tatagcctgt aaaaagtgaa aggcagagag ctccaaatgg
    21061 catgagaaga ttggaaacca agaaatccat ggcatcaaag aaagttttac caaagatgtg
    21121 aacatccgcc ataactccat aggatagggc tgaaggaatg ccaaagacaa aggtcaaaat
    21181 tcctaaaata acactccatt tggcacgttt gctgttgtcc tgattggtga tattgtctac
    21241 attgatttcc agcataacga cagaagaagt gacagtcgca aagaggaaga ggacatagaa
    21301 aatggttcca aaaggcatct tgtcaaagag ttgaggcaag acgataaaga ccaagctcgg
    21361 tcccccttca gactggatat tgaaggggga ccgagcttgg aaaatggcta gacctgccat
    21421 gatggatacc gagatattca tggctacgat ggagattctt gactggacca gattggtttt
    21481 cttgtccaag taagaagcat aggtcaacat ggctgtaacc cctagtgaga gggcaaagaa
    21541 agattgtctc agagcataga ggagaccagc gctagtcagt tttgaaaagt ctggtttgag
    21601 gaagtaaaga accccttcca tggcatttga caagctgaga gagcgaccga tgataacaac
    21661 aaagatgata aagagcaggg gcatcatgac tttcgaagct ctttcaatcc ctttttgaac
    21721 cccacgtgat acaatgaaga tattcaatag gataaaggcc gcttgagctc ctagggcaat
    21781 ggctggattt gaaatgatca
//
LOCUS       DAVMBH010000034        21292 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVMBH010000034 DAVMBH010000000
VERSION     DAVMBH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.034"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            63..785
                     /locus_tag="VYP30_001455"
     CDS             63..785
                     /locus_tag="VYP30_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1808435.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1003..2337
                     /gene="pepC"
                     /locus_tag="VYP30_001456"
     CDS             1003..2337
                     /gene="pepC"
                     /locus_tag="VYP30_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1808436.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2393..3304)
                     /locus_tag="VYP30_001457"
     CDS             complement(2393..3304)
                     /locus_tag="VYP30_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1808437.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3328..4131)
                     /locus_tag="VYP30_001458"
     CDS             complement(3328..4131)
                     /locus_tag="VYP30_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1808438.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4159..5148)
                     /gene="manX"
                     /locus_tag="VYP30_001459"
     CDS             complement(4159..5148)
                     /gene="manX"
                     /locus_tag="VYP30_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1808439.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5381..6400)
                     /gene="adhP"
                     /locus_tag="VYP30_001460"
     CDS             complement(5381..6400)
                     /gene="adhP"
                     /locus_tag="VYP30_001460"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1808440.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(6739..7551)
                     /locus_tag="VYP30_001461"
     CDS             complement(6739..7551)
                     /locus_tag="VYP30_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1808441.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7741..9159
                     /locus_tag="VYP30_001462"
     CDS             7741..9159
                     /locus_tag="VYP30_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1808442.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9212..9919
                     /locus_tag="VYP30_001463"
     CDS             9212..9919
                     /locus_tag="VYP30_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1808443.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            10014..10988
                     /gene="folP"
                     /locus_tag="VYP30_001464"
     CDS             10014..10988
                     /gene="folP"
                     /locus_tag="VYP30_001464"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1808444.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            10990..12312
                     /locus_tag="VYP30_001465"
     CDS             10990..12312
                     /locus_tag="VYP30_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1808445.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            12293..12847
                     /gene="folE"
                     /locus_tag="VYP30_001466"
     CDS             12293..12847
                     /gene="folE"
                     /locus_tag="VYP30_001466"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1808446.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12890..13702
                     /gene="folK"
                     /locus_tag="VYP30_001467"
     CDS             12890..13702
                     /gene="folK"
                     /locus_tag="VYP30_001467"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1808447.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(13747..14064)
                     /locus_tag="VYP30_001468"
     CDS             complement(13747..14064)
                     /locus_tag="VYP30_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1808448.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            14421..14867
                     /gene="rplM"
                     /locus_tag="VYP30_001469"
     CDS             14421..14867
                     /gene="rplM"
                     /locus_tag="VYP30_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1808449.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14886..15278
                     /gene="rpsI"
                     /locus_tag="VYP30_001470"
     CDS             14886..15278
                     /gene="rpsI"
                     /locus_tag="VYP30_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1808450.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(15566..16720)
                     /locus_tag="VYP30_001471"
     CDS             complement(15566..16720)
                     /locus_tag="VYP30_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1808451.1"
                     /translation="MSIHKYKTKKGVLYYVSFYIGLDAYGKKKRHLKRGFKTKKEAKL
                     YEARLEAGVVAPTVNTDKPNPKVTYKEFYQEWFKAYVGTVEETTSSQTKNIYRIHILP
                     IFGGKFIDQISPLDCQNFITQKSQTFKNIKQIKSYTSKIFDFAINMNYIDRNPMKNVI
                     MPKIKKTRSDNFWSLEELHHFLDIVKETEPFKHFALFRLLAFSGLRKGELYALKWADI
                     NFDSNLLNIDKSLGRIDGKAIEKSTKNESSVRTIYLDDETIDIIKQWRNFYLKEQSQF
                     PLTKLNISNEYMFYYISSNDKIEPLHADYINNVLNRIIKKHKLKPISPHGFRHTHATL
                     MSEIGIDPSNTSKRLGHASSQMTLDVYTHTTKTGEKNSIDKFADYLNKAK"
     gene            complement(16772..17290)
                     /locus_tag="VYP30_001472"
     CDS             complement(16772..17290)
                     /locus_tag="VYP30_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808452.1"
                     /translation="MSNHITKLIEDSGKKLTEISEATDIAYPTLSGYNQGIRKPKKDN
                     AEKLAKYFNVSVAYIMGLDSNPHAPSNLKIVTDSFKTSKIGSVTPFKSDMEKLKKSIE
                     FGERALTLPLDDSFSDEFRHIFSEYLAEKNKRFMSEFIDYMNHQNKDSKVWQSWIKTD
                     EYAIRQEDRKNR"
     gene            17438..17719
                     /locus_tag="VYP30_001473"
     CDS             17438..17719
                     /locus_tag="VYP30_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1808453.1"
                     /translation="MSETTLVVQLPKELEKQLRAHYDEMISNAVARVFEDKELYKPMV
                     RMSGLSRWLDVSTTTIQKWTKEGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            17728..18567
                     /locus_tag="VYP30_001474"
     CDS             17728..18567
                     /locus_tag="VYP30_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001014724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1808454.1"
                     /translation="MNGVQWIKITTDIFDDEKIQLIESMPEGDTLIVIWFKLLVLAGK
                     QNNSGILSLGNKVYYTEEMLSTVFRRKATSVKLALSMFEEFGMIEIIDGAITIPKWEK
                     HQNIDGLEKIRKQTRERVARHRQKQKALIKGEPQLILDCNVTVTDENENVTQEIKNES
                     KNKKEIENILDNSSRKPETYIPPKYYSLLESISYKYNDRFLYPNNYTLTHAQKMKIGE
                     YLASGYVTSDEVISMIERIPEDAASPLAYLFKSMENLKQERMLECKTIAHENARKKYM
                     INE"
     gene            18560..18919
                     /locus_tag="VYP30_001475"
     CDS             18560..18919
                     /locus_tag="VYP30_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808455.1"
                     /translation="MSRYRTILKKFYITEEQNEIANNLIKMTNHLSFSSYARKMLFKR
                     SPIYLQFDFKSYHDFIFQVRRIINNLRQLERIAKQSEDLDNVRIFHCCVEMMIGYEKK
                     TSKQVKELVKRLNKKTR"
     gene            18927..19259
                     /locus_tag="VYP30_001476"
     CDS             18927..19259
                     /locus_tag="VYP30_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808456.1"
                     /translation="MRIKSVLKQVFLTEEENKKLNDCMRKENICNFSEFARKKLIRTD
                     LNIHKVSFEGLVPLTEELEQVGKNINSIARLATVVGRISYENKMDMSIMMQKIVDVME
                     EKDVYFQK"
     gene            19240..19434
                     /locus_tag="VYP30_001477"
     CDS             19240..19434
                     /locus_tag="VYP30_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808457.1"
                     /translation="MFIFKSSMDKDFDQICEYILKLKRAELFLHGIKQQDKTKARLYH
                     AMLEYYDANHKKVRHMRILK"
     gene            complement(19825..20121)
                     /locus_tag="VYP30_001478"
                     /pseudo
     CDS             complement(19825..20121)
                     /locus_tag="VYP30_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            20529..21197
                     /locus_tag="VYP30_001479"
     CDS             20529..21197
                     /locus_tag="VYP30_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001158457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HEV1808458.1"
                     /translation="MQETMIDYKQKIYQELSRLTKGLGSEKRLDILNILSQGPKTVEG
                     IAHTTGLSVANTSRHLQILKESHLVVTSRNGNFIRYSLASEKVVQLVLLLFAVGEEQL
                     AEVRAIESDYDEAAGVPQIELANAIELAAKTDALLLDLRPVEEYEAGHLPKALNLPID
                     EFDQKKAQLPKEKTIIVYCRGRQCGYANLAAQDLQSLGYSIYSLNRSFADWKWGASSR
                     SELD"
BASE COUNT         6403 a         3905 c         4567 g         6417 t
ORIGIN      
        1 aatagttcac ctaataaaat gttagttatg tacaacaata atttccatga tataatagtt
       61 ctatgagatt agataaattt ttagttgcct gtgcggtggg aagtcggact gaggtcaaaa
      121 acttgctcaa ggctgggcgc gtgactgtaa atggtaaaaa agaaaaatca gctaaattgc
      181 agattgatga aaaaatagat gagattcgct ttgatgggca agtgttggag tatgaagagt
      241 ttgtctacta catgatgaac aagcccaaag gagttatctc agcgactgag gatcccaagc
      301 acagaaccgt tctggacttg ttggatgact tggcgcggag taaggaagtt ttcccagtag
      361 gacgcttgga tattgacacg catggtcttt tgctcttgac caatgatggt cagctggctc
      421 atgttcttct ttcgcccaag cgtcatgtgg acaagactta tctggcacaa gtcaagggaa
      481 tcatgaccca agaagatgtg gagacatttg ctgagggtat tcctctcaaa gactttacct
      541 gtcaacccgc tatactggag cttgtatcca tagatacaga aaagaatcaa agccaaatcc
      601 gtgtgaccat tgcagaaggg aagtttcatc agatcaagcg tatggtgggc tactgtggca
      661 aggaagtggt ggacttgcaa cgattgacta tgggaacttt agtattagat gagaacctgg
      721 aacgagggga atggcgtcgc ttgaccaagg aagaattaga aattctccgc gctaatatta
      781 tttaatttag tttaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc
      841 tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc gaagagtata
      901 aattcgaaaa aggtgaggga caatgtcctc gccttttatg ttttttagtt gcttcctttg
      961 tgaaaagagt tataatagac tgtagaataa aaggaggaat ctatgaacgc gattcaagaa
     1021 tcatttactg ataaactatt tgccaactat gaagcaaatg taaaatacca agcgattgaa
     1081 aatgctgcca gccacaacgg aatttttgca gctctggaac gtcgccaaag ccgtgtagac
     1141 aacacacctg ttttctcatt ggatttaacc aaggacaagg tcactaacca gaaagcgtct
     1201 ggtcgttgct ggatgtttgc ggctctcaac accttccgcc acaaactcat ctcgcaatac
     1261 aaattggaga actttgagtt gtcacaagcc cacactttct tctgggataa gtatgagaaa
     1321 tcaaactggt tcttggagca agtcattgcg acttcagacc aagaattgac tagccgcaag
     1381 gttagcttct tactccaaac acctcaacaa gatggcggtc aatgggatat ggtcgtttcc
     1441 ctctttgaaa aatacggtgt cgtgcctaag tcagtttatc ctgagtctgt ttcatctagc
     1501 agcagtcgtg agctaaatgc gatccttaat aaattgcttc gtcaagatgc tcaaatcttg
     1561 cgtgacttgc ttgtttctgg tgcagatcaa gcgactgttc aagctaagaa agaagacctc
     1621 ttgcaagaaa tctttaactt tcttgctatg tcattaggac ttccaccacg caagtttgac
     1681 tttgcttatc gcgataaaga taacaactac aaaagtgaaa aaggaatcac accacaagag
     1741 ttttacaaga aatatgtcaa tcttccttta gaagactacg tttctgttat caatgctcca
     1801 actgctgata aaccttacgg aaaatcttac acagttgaga tgttggggaa tgttgttggt
     1861 agccgtgcag ttcgctacat caacgttcca atggagcgct tgaaagaatt ggcgattgcc
     1921 caaatgcaag caggtgagac tgtttggttt ggttctgatg tcggccagct cagcaaccgt
     1981 aaggctggaa tccttgcgac agatgtttat gactttgaat caagcatgga cattaaactt
     2041 actcaagaca aggctggacg tttggactat agcgaaagct tgatgaccca cgccatggtc
     2101 ttgacaggtg ttgacttgga cgaaaatggt aaatcaacca agtggaaggt tgaaaactca
     2161 tggggagaca aggtcggtac agatggttac tttgttgcct cagacgcttg gatggacgaa
     2221 tacacatacc aaatcgttgt tcgtaaggaa ttgctgacag cagaagaaca agctgcctat
     2281 ggagcagaac caatcgtact tgcaccatgg gatccaatgg gagccttggc tgaataaaag
     2341 catagaaaaa aggaatcaga ttttagaacc tggttccttt ttagttgctt gattacatga
     2401 tgtgaagaac atgtgccaca atacccactg cgaagagggc aaggataata gtgattggag
     2461 atactttttt cttaagtaag tacatgcaaa gtaaagtaag gagtagtcct gataatccag
     2521 gaatcaacat atccaagttt tgttggaaag tagtaacttt ttcaggagtt tgagacaatc
     2581 cttgtcctac ttgtgcgaat gcttcttgga tacctttaga cccttctggc aatttatccc
     2641 aatggatata agccttttca tctagttgaa ctttagaaac atcgaaagca aatttaatat
     2701 ttacccaacg ttgaacaagg acagcaagaa tgaacatccc aaggatagaa gctcctttag
     2761 tgatatcttg aaggatacca ccagacatat ctttagtgat ttctgatcca gccttgtatc
     2821 caatctcttg aacataccac aagaatgaca tacgaatcaa gttccatgca acaaagaaga
     2881 ggagtggccc caagatattg ccagtaaggg caagtgaagc accgagagat ccaaggattg
     2941 ggcgtactgt aaaccagaat actgggtcac cgataccagc aagaggtccc atcataccga
     3001 ttttgacccc ttggatagca gcgtcatcga tttccacacc gttagcacgt tcttcttcaa
     3061 gcgcaagagt aacccccatg actggagcag ctacgtatgg atgagtgttg aagaactcaa
     3121 ggtgacgctc aagagcagcg atttgatctt cttttttagt atagagtttt ttgatagctg
     3181 gaatgagtgt ataagcccag cccaagtttt gcatccgttc aaagttccaa gacccttgta
     3241 agaaggttga acgccaccaa acttttttac gatctgattt agttaattga agtttttcag
     3301 tcatgatgtt ttcagtcctt tcttatctta gtagtcttct aggatatcgc cgattgggtc
     3361 gttagaagtt gcggctcctc cgccaccatt tccaccagtt ttagaaaggt gaaggtagat
     3421 aagagcgata gcaacaccga tagcaccgaa tccgattaga gtaatatctg acacagcagc
     3481 gagaacgaaa ccaagagcga agaatggcca tacttcacga gttgccatca tgttgataac
     3541 catggcgtaa ccaacggcaa cgaccatacc accaccgata gccataccat ctttgagcca
     3601 gtctggcatg gcactaagga tactttgtac agtttcagtt ggtaccataa ggagaagagc
     3661 tgcaggaagc gcgatacgaa gtccttggaa gagtagcgca atgaaatgcg cacgctccac
     3721 agcgccgaag tcaccttttt tagcggcagc atctgcagta tgaaccaaac caactgaaat
     3781 tgtacgaaca atcattgtca agaaaagtcc agctacggca agagggatag caaccgcttg
     3841 ggcaacaccg ataccagtct tggtaaagtc accaccaaga accatgataa tggcagcagc
     3901 gacagaagca agtgcagcat caggagcgat agcagcaccg atatttgacc aaccaagggc
     3961 aatcatttga agcgatccac cgaggataat ccctgcttcc aagtgacctg ttacaagccc
     4021 aataagggta caggctacaa gtggttggtg aaattggaac tggtcgagga tgccttcaag
     4081 acctgcaaag aaggctacaa cgactactaa aaccatagaa ataatagaca tgtttaaaat
     4141 cctttcataa ataatggctt atttgacatt ggctttgtta atcaagtcaa acaaatcttt
     4201 tttagaatca tttggtactt tacggacatc aaattcaaca cccaagtcac gcattttttc
     4261 aaatgtcgca acatcttctt tgtccataga caaaacggta ttgaccaatg ttttacctgt
     4321 tgagtgagcc atagaaccaa cgttaagagt cttgattggc acgccgcctt cgatggcacg
     4381 aagggcatct tgaggtgttt caaacaagat aagggcatgt gtttctccaa aacgtgggtc
     4441 ttttgaaatc tcaatcagtt tttgaattgg aaccacgtta gccttgacat tacctggagc
     4501 tgcttgttta atcaattctt tacgaaggtc gtctttagcc acattatctg aagcaacgat
     4561 gatacgattt gcttttgaat ctggagtcca agcagttgca acctgaccgt gaagtagacg
     4621 tgtgtcaaga cgggcaagat tgattttcaa tttaccgtct ccgataacag ttccttctgg
     4681 gatagcagtt tgggcaactg gagcagctgc agcgcttgca acttcttcaa ctggatttag
     4741 ctcttctgga agagctttga tgccatcttt ggcttcttta atgatattag cagcgacttt
     4801 ttctacacct gcagcagcgt ccatgaggcg ctctgtgtag gcttgaatca acatcggtaa
     4861 gttaagtcct gtgatgatgg caaacttacg ctcaggattt tctcccatca cgcgactagc
     4921 ttggttaaat ggagaaccac tccaaaggtc agccaaaact agaacctcat cttctgcgtc
     4981 aaatgcagca acagcgttat taaacttagc gtatagatca tcaggacctt catttggcat
     5041 aaaggtcaca acttgaacct tttcttgttc accaaagatc atagatcctg actgatgaat
     5101 acccgcagca aattcgccgt ggctcgcaat aatgattccg atactcatta ttgtcattcc
     5161 tccttttttg ttttagtttt catttaagaa aactttaaga ctgtttaagt ataaaccgtt
     5221 ttcataaaaa aagcaactat ttatcataaa aaattaaaaa atttttattt ttgtatgttg
     5281 atatgttgag tttttgagga gtaatcttga attcttattt aaaatttaat ataaaaaagt
     5341 tggaagaagc ttccaacttt taaaataggt ttctattaga ttagtgggtg aagtcgagta
     5401 ccatacgtcc ttggatttgg cctttttcca tttcgtcgaa aatggcaaca gcatcttcta
     5461 ctggacgttt ttgaacaact gggactacca gaccttctgc accaaattgg aaggcttctt
     5521 ctaagtcttt acgagttccg acaagagaac cgatgacttg gattccatcg aggactgttt
     5581 taacgatgct gagttccatc atttcagaag gaagaccaac agcgacgacg cgaccaccag
     5641 cacgaatgga gtcaacagcc tggttgaagg caactttaga cacagcagtt acgacagctg
     5701 aatgagctcc tccatcagtt ttttctttaa tgagtccagc tacatcttca acttcgaggc
     5761 cgttaatcac aatgtcagcg cctacttctt ttgcaagggc aagtttgtca ttgttgatat
     5821 cgactgcgat aacatgagca ttgaatactt ttttagcgta ttgaacagcg aggttaccaa
     5881 gtccaccagc accgtaaaga acagcccatt ggcctggttc aacttttgct tctttgatag
     5941 ctttataggt tgttactcca gcacatgtga tagaagaagc ttgggctgga tcaagtccgt
     6001 caggaacttt gacagcatag tcagcagtta cgatacattg ttcagccata ccaccgtcta
     6061 ctgagtagcc agcatttttc actgtacggc aaagggtttc gcgaccagtt gtacagtatt
     6121 cgcaagtgcc acatccttca aagaaccaag caacgctgac gcggtcaccg actttaaggc
     6181 ttttcacatc tggagcaatc tctttaacga taccgatacc ttcgtgccca agaacacgtc
     6241 ctgggacttg accaaagtca ccatgagcaa cgtggaggtc ggtgtggcaa acgccacagt
     6301 attcaacttc tacaagtgct tccccagttt caagtggacg gagtactttt tcttcaatag
     6361 caacaccagt gctttctgga tttacaacaa cagctttcat agctatcctc cttgatattg
     6421 accgagaaca gggacaacgg gactggattg attttttgtc aacagagtcg agtgtgacga
     6481 gctctcttgt atttatatgt gaagtatatc acaaaagaaa gccttttcca aggttttgga
     6541 gacaaaaagt agaacaatcg attaactggt tgatgagact gtgaaaagag cacaaagacc
     6601 agcttgcaag ctggtcatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcatctaca
     6661 acctcaaagc agtgctttga gcaacctacg gctagcttcc tagtttgctc tttgattctc
     6721 attgagtatc agtataggtt ataagaataa gtcttgtagg gttttggcaa ccccatcttg
     6781 gtcgttggta agggaaattt gctcatctgc ataagggagt agctctggat tggcattttt
     6841 catggcataa cccttcccag caaaagcgag catttcggta tcattgtgtt catctccaaa
     6901 ggcaatcaaa tcttttttgt cacgattcat tatcttgagc aagtagtcca aagcaaaggc
     6961 cttgttgaca ccttttgggg tacattcaag gatattgagc ggacctcccc aggtattgat
     7021 agaaagttga tgctggtaga aggcgttcat ttcttttgcc aaggcatatt tgtcactggc
     7081 tctggtctgc aagaggatac agttagggtc cttggtcacc aattcaggct ggaattgatc
     7141 ttcaggctgg aaagcttcta caccaaatag tttgggattg gcaatttctt cattgggatt
     7201 tgtaatgtag aattttttac gatattctcc agcgataaaa tcggcttgaa tgtcctctga
     7261 acgttgaacc atatctagca gatatttttt gtctacagtc aaacactttt caaaatccca
     7321 aacttggtct ggtaaatgag taagggatcc gttgaagtta atcataggag tgtctaagcc
     7381 cagttcacgg taaaaatctt ttgacatacg gtaagggcga cctgtcgtaa taataacctg
     7441 atggcctttt tcagcaactt ttttgatggt ttttttggta aagtcagaaa tttgactgtc
     7501 tgagttgagc agggttccat ctaggtcaac tgcaataatt tttttcgtca tatggacctt
     7561 tctagtgtgt tttcagataa gatgtcttct attataacag aaagcaggca gaaaagcaga
     7621 ttccaaacaa aaaatgaaat tggattaatt tcttaaacaa atcaaacaaa gacattgaaa
     7681 aagtgaatga taaatgatat aattctatta ttgttcgtaa aaattaaaag gagattgatg
     7741 atggacaaat tatttaaact aaaagagaac ggtacagacg ttcgtacaga ggttctcgct
     7801 ggtttaacaa ctttctttgc aatgagctat attctctttg taaacccaca aattctttcg
     7861 caaacaggaa tgcctgctca gggtgtgttt cttgcaacga ttatcggtgc agttgctggt
     7921 accttgatga tggccttcta tgctaacttg ccatacgctc aagcaccagg tatgggactc
     7981 aatgccttct ttacctttac agtcgtattt ggacttggtt attcatggca agaagcccta
     8041 gctatggtct tcatctgtgg gattatttca ttggttatta ccttgacaaa tgttcgtaaa
     8101 atgatcattg aatcgattcc aaatgccctt cgctcggcta tttcagctgg tatcggtgtc
     8161 ttccttgcct atgtagggat taagaatgct ggacttttga aatttacgat tgatccaggc
     8221 aactatactg ttgtaggaga aggggctgac aaagctcaag caacgattgc agcaaactct
     8281 tcagcagttc caggcttggt cagctttaat aatccagctg ttttagtggc tcttgcagga
     8341 cttgccatta ctatcttctt tgtcatcaaa gggattaaag ggggaattat tctctctatc
     8401 ttgacaacaa ctgttcttgc tattgcagtt ggtttggttg atttgtctag tatcgatttt
     8461 gctaataacc atgttggtgc agcttttgaa gatttgaaga caatctttgg tgcagctctt
     8521 ggttcagaag gtttgggagc tttggtttca gatacagctc gcttgcctga aactctgatg
     8581 gccattcttg ccttctcatt gacagatatt tttgacacaa ttggtacctt gatcggtaca
     8641 ggtgaaaaag ttggtattgt agcgacaaat ggtgaaaatc accaatcagc caaattggat
     8701 aaggctcttt actctgattt gattggaacg acagtcggtg ccattgcagg tacttcaaac
     8761 gtaacgactt atgttgagtc tgctgctggt atcggtgcag gtggacgtac tggtttgaca
     8821 gccttggttg tagctatctg ttttgcgatt tcaagcttct ttagcccact tctagcgatc
     8881 gtaccaacag cggctacagc tccaatcttg attatcgttg ggattatgat gcttggtagc
     8941 ttgaaaaata tccattggga tgatatgtct gaagcagttc ctgccttctt cacatctatc
     9001 tttatgggat tcagctactc tatcactcaa gggattgcag ttggtttctt gacttacact
     9061 ttgactaagc ttgtcaaagg tcaagttaaa gatgttcatg ccatgatttg gattttggat
     9121 gccttgttta tccttaacta catcagcatg gccttataat agaatgaccc agggggattt
     9181 cccccctttt ttaatacaaa ggagataggt gatgaaagag aaaaatatgt ggaaagaatt
     9241 gttgaatcgt gcaggctgga ttttggtctt tttacttgcc gtccttttat atcaggttcc
     9301 cctagtggtt acctctattt tgactttaaa agaagtagcc ctgctacagt cagggctgat
     9361 agttactggc ctttcaattg tggttctggc tctatttatt atgggagctc gtaaaaccaa
     9421 gttagctagt tttaattttt ctttttttag agctaaagat ttggcacgtt tgggcttgag
     9481 ttatttagtt attgtcgggt caaatatact tggttctatc ttgttgcaac tgtcaaatga
     9541 gacgacaaca gctaaccagt ctcagattaa cgatatggtt cagaatagtt ctctgatttc
     9601 tagcttcttc ttgctagcct tgcttgctcc aatttgtgag gaaatcttgt gccgtgggat
     9661 tgttcctaaa aagattttcc gaggcaagga gaacttggga tttgtagtcg gtacgattgt
     9721 gtttgcttta ttgcatcaac caagtaattt accttcttta ttgatttatg gaggtatgtc
     9781 gacagttcta tcttggacgg cctacaagac ccaacgtttg gaaatgtcga tcttgcttca
     9841 catgattgtt aatgggattg ctttctgttt gttggctctt gtggtgatta tgagtcggac
     9901 attaggaatt tctgtttaaa agtttttatg taggaaccga cctctttcta ctagggaaag
     9961 atgaatgcaa tcgtgtccat ctttttcttt ttatggtaaa atagaaaaat aatatgatga
    10021 aaatccttga gggagtgacc gatatgtcaa gtaaagccaa tcatgcaaag acagttattt
    10081 gcggaattat caatgtaacc ccagactcct tttcggacgg tggtcaattt tttgctcttg
    10141 agcaggcact ccagcaggct cgtaaattga tagcagaagg agccagtatg ctcgatatcg
    10201 gcggagaatc gactcggccg ggaagtagct atgttgagat agaagaggaa atccagcgtg
    10261 ttgttccagt gatcaaagcg attcgcaagg aaagtgatgt cctcatctct attgatactt
    10321 ggaagagtca agtagcagag gctgctttgg ctactggtgc cgatctagtc aatgatatca
    10381 ctggtctcat gggtgatgaa aaaatggccc atgtggttgc taaagctgga gcgaaagtgg
    10441 tcatcatgtt taacccagtt atggctcgac ctcagcatcc tagttcgctt atcttccctc
    10501 attttggctt tggtcaaacc tttacagaaa aagagttagc tgactttgaa acattgccaa
    10561 tcgaagactt gatggtggct ttctttgaac gagcactagc gagagcggca gaagctggta
    10621 ttgcaccaga aaatatcctg ttggatccag gaattggctt tggtctgacc aagaaagaaa
    10681 atcttctcct tttacgggac ctggataaac tacatcagaa gggctatcca atctttctcg
    10741 gagtgtcgcg caagcgattt gtcatcaata tccttgaaga aagtgggttt gaagtcaatc
    10801 ctgagacaga gcttggtttc cgaaatcggg acacggcttc ggctcatgta actagtatcg
    10861 ctgcgagaca gggtgtagaa gtggtgcgcg tgcatgacgt agctagtcac aggatggcag
    10921 ttgaaattgc ctctgccatt cgtctggctg atgaagcgga aaatttagat ttaaaacaat
    10981 ataaataaga tgaaagaaat tgaaaacaat cagtggattg ctaactaccg gacggatcaa
    11041 ccgcattttg gcttggaacg aatggtggaa ctgttagctt tgcgtggcaa tccccatctt
    11101 aaactcaagg ttctccatat cggagggact aacggcaagg gctcgactat tgcttttttg
    11161 aaaaagatgc tagaaaagct agggctgaga gttggcgtgt ttagttcgcc ctatctcatt
    11221 cattacacag accagattag catcaatggg gaatcgatct cagaagcgag gctagaagct
    11281 ctcatggcag actatcagtc tttgctggag ggagaagcgg tcgccaattt acagggcaca
    11341 accgagtttg agattatcac agccctagcc tatgactact ttgcctcaga gcaagtagat
    11401 gtggctatca tggaagttgg catgggtgga cttttggata gtaccaatgt ctgtcagccc
    11461 attttgacag gaattacaac tattggcttg gatcatgtgg ccctacttgg tgacaccttg
    11521 gaggccatag cagagcagaa ggcaggtatt atcaaacaag ggatgccctt ggtaacaggg
    11581 cgtattgctc cagaagcctt gactgtgatt gaccgcattg cggaagggaa agatgcgccg
    11641 agacttgcct acgggacaga ttatcaggtt cgtcatcaag aaagtgtggt gacaggggaa
    11701 gtctttgact atacaagtgc tgtcagacaa ggtcgcttcc agactagcct gcttggtttg
    11761 taccaaatag agaatgctgg gatggccata gctttacttg atactttttg tcaagaagat
    11821 ggtcgagagc tagcaagcaa tgactttctt ggtcaagcct tggaagaaac aagttggcca
    11881 gggcgtttgg aaatcgtgtc aagagatccc ttgatgattt tggatggagc ccataatccc
    11941 catgctatca aggccttgtt ggtaaccttg caagaacgtt ttgcggatta tcataaggaa
    12001 atcctcttca cttgtatcaa aaccaaagcc ttgggggata tgttggactt gctgggagcc
    12061 atgccagata ccgagcttac tctaacacat tttgcggata gtcgggcgac ggatgaaagc
    12121 gtgctgaaag aggcagctaa gtctagaaat ctcagctacc aagattggca tgattttcta
    12181 gagcagaatt tgacagataa aaaagaagag aaacaaacag ttaggattgt cacaggttcc
    12241 ttgtatttct tgagccaagt gagggcctat ctgatggaga ggaagaacga gaatggatac
    12301 acaaaagatt gaagcagctg taaaaatgat tatcgaggct gtaggagaga acgctaatcg
    12361 cgagggcttg caggaaacac ctgctcgtgt agcccgtatg tatcaagaga ttttttcagg
    12421 tcttggtcaa acagcagagg aacatttgtc aaaatccttt gaaattattg acgataatat
    12481 ggtggtagaa aaggatatct ttttccatac catgtgtgaa caccacttct tgccatttta
    12541 tggtagagcg cacattgcct acattccaga tggtcgtgtg gcaggcttgt ctaagctagc
    12601 ccgtacggtt gaagtttatt cgaaaaaacc acaaattcaa gaacgtttga atatcgaagt
    12661 ggccgatgcc ttgatggact atctaggtgc taaaggagcc tttgttgtca ttgaggcgga
    12721 acatatgtgt atgagtatgc gtggtgttag aaaaccaggc actgcaacct tgacgacagt
    12781 agctcgtggt ctatttgaaa cagataagga cctccgcgac caagcttatc gtttaatggg
    12841 gctataaaaa gaatccgttt caagcggatt tttctagaaa ggaatcatta tggatcaact
    12901 gcagattaag gatttggaaa tgtttgccta tcatggtctt tttcctagtg agaaagaatt
    12961 ggggcagaaa tttgtcgttt cagccatcct atcctatgat atgaccaagg cagctacaga
    13021 cttggattta acagcctctg tccattacgg agaattgtgt cagcagtgga cgacttggtt
    13081 tcaggaaacg agtgaagatt tgattgaaac ggtagcctat aaactggtgg aacgtacctt
    13141 tgagtcttat cctcttgtcc aagaaatgaa gttggaactg aaaaaacctt gggcaccggt
    13201 gcatttgtca ctagatactt gctcggtaac cattcatcgc cgcaagcaac gagcctttat
    13261 cgccctagga agcaatatgg gagataaaca agcaaacttg aagcaagcca ttgacaaact
    13321 gcgagctcgt ggcatctata ttctcaaaga gtccagtgtc ttagcgacgg agccttgggg
    13381 tggagtggag caggatagct ttgccaatca agtggttgag gtggaaacct ggctaccagc
    13441 acaagacttg ttagaaacct tgttagccat tgagtcagag ctgggacggg tgagagaagt
    13501 gcattgggga cctcgtttga ttgatttgga cttgctcttt gtggaggacc agatccttta
    13561 tacagacgac ctcatattgc ctcatcctta catagcggaa cgcctttttg tccttgagtc
    13621 cttacaggaa attgcgcctc attttatcca tccgatatta aaacaaccga tccgtaactt
    13681 gtatgatgct ttgaaaaaat agaaaaactc tagttttcag ttacttgcaa ctgaaggcta
    13741 gagtttttaa aataggtcat tttcttctgg gaggaggata gtttctctac cgtccatgtc
    13801 taaaaccagt actcttgggg gataacgagg gtcgaaagga tggttaaagt caaaatcaat
    13861 ggctgtaggg aggtgttgac ttgaaaagtg gaaggtaatc tttccttggt tattaagcaa
    13921 ttgaaactcg agttcttctt ccaattcaaa gacatttttt aagaaatggt cgataatata
    13981 ccaaaaagag tcaatgatgt catcaggcaa gctggtaaca atgccaaaac tagcagaccg
    14041 catgtgggta ttggtaaaag ccatatctct gtctcctttc ttttccctta tcatacagca
    14101 aataggatta aaaatcaaga aaaggtgatt ttttgaaaag gattttaact acagggaaaa
    14161 agaaggaaaa aaattcccaa aaatctaccg aagttaatag gtaaattccc aaattaactt
    14221 gattatataa ctttcagtta ttttgagaag ttaccgaaaa atatttttta tatctattga
    14281 cttttagggg tgaaatttgg tatgatagta ggcggtattg tttaccccat ttgaaaggcc
    14341 ccggaacctt ccaaatactt ttcgatggga aggaacaccc atcaccgtaa acaaaaatcg
    14401 aactatatat aggagaaatc atgaacaaaa caacatttat ggctaaacca ggccaagttg
    14461 aacgtaaatg gtacgtagtt gacgcaactg atgtaccact tggacgtctt tctgcagtag
    14521 ttgctagcgt acttcgcgga aaaaacaaac caacatttac accacacact gatacaggtg
    14581 acttcgtgat tgttatcaat gctgaaaaag ttaaattgac tggtaaaaaa gcaactgata
    14641 aaatctacta cactcactca aaccacccag gtggattgaa acaaatctct gcaggtgaac
    14701 ttcgttctaa aaatgcagta cgtttgattg agaaatcagt taaaggtatg cttccacaca
    14761 atacacttgg acgcgctcaa ggtatgaagt tgaaagtatt tgttggagct gagcacactc
    14821 acgctgcaca acaaccagaa gttcttgaca tttcaggact tatctaagga aaggaacaat
    14881 aaagtatgtc acaagcacaa tatgcaggta ctggacgtcg taaaaacgct gttgcacgcg
    14941 ttcgccttgt tccaggaact ggtaaaatca ctgttaacaa aaaagatgtt gaagagtaca
    15001 tcccacacgc tgaccttcgt cttgtcatca accaaccatt cgcagttact tcaactgtag
    15061 gttcatacga cgttttcgtt aacgttatag gtggtggata cgctggtcaa tcaggagcta
    15121 tccgtcacgg tatcgctcgt gcccttcttc aagtagaccc agacttccgc gattcattga
    15181 aacgcgcagg acttcttaca cgtgactcac gtaaagttga acgtaagaaa ccaggtctta
    15241 agaaagctcg taaagcatca caatttagta aacgttaatt cgaaagaatt actatactta
    15301 tacagagcac ctttcggggt gttctttttt tatactttct tactaaattg gtgcaattga
    15361 cacagttgtt gcgactttag tcgcttacaa atgtggctgc aacctgacaa ggtcagttgc
    15421 ctcaaaacgt taatcaatac gattatatca acgtttcaaa gcactttgca aagattttgc
    15481 aaagtgcttt tttgtcgatt tttgagctcg aatagctttg tgataacctt ctgataacct
    15541 cttttagatt ttaaacatca tgattttact ttgctttatt gagataatct gcaaatttgt
    15601 caatagagtt tttctcacca gtttttgtgg tgtgagtata gacatctaat gtcatctgac
    15661 tgcttgcgtg accgagtcgt tttgatgtat tagaaggatc gattccaatt tcagacataa
    15721 gtgttgcatg tgtgtgtctg aacccatgtg ggctaattgg ttttaattta tgctttttaa
    15781 taattcgatt cagtacgtta ttaatgtaat cagcatgcaa aggttcaatt ttgtcattac
    15841 ttgatatgta atagaacata tattcgttac taatattcaa ctttgtaaga ggaaactgag
    15901 attgttcttt cagatagaaa tttctccatt gcttaataat atcgattgtc tcatcatcaa
    15961 gatagattgt acgaactgaa gattcattct ttgtgctctt ttcaatcgct ttaccgtcaa
    16021 ttcttcctag acttttatct atgttcaata gattgctgtc aaagttaata tcagcccatt
    16081 ttaaagcgta taactcccct tttcgtagtc cactaaatgc aagcagtcta aataaagcaa
    16141 aatgtttaaa tggctcagtt tctttcacta tatcaaggaa atgatgtaat tcctccagag
    16201 accaaaaatt atctgatcta gtttttttga ttttaggcat gataacattc ttcattggat
    16261 ttcgatcaat gtagttcatg ttgattgcaa aatcaaaaat ttttgaggta taggatttta
    16321 tctgtttgat atttttgaaa gtctgagatt tttgtgtaat aaagttttga cagtctaaag
    16381 gactgatttg gtcaataaat ttaccgccaa atattggtag aatatgtatt cgatagatat
    16441 tcttagtttg ggaagaagtt gtttcttcaa cggtaccaac atatgcctta aaccattctt
    16501 gataaaattc tttataagta actttgggat taggtttgtc ggtatttact gtaggggcga
    16561 cgacaccagc ttctaaacga gcttcgtaca attttgcctc ttttttggtt ttgaatcctc
    16621 tctttaagtg cctttttttc tttccataag catctaagcc aatgtaaaag ctgacatagt
    16681 aaaggactcc tttttttgtt ttgtatttgt gtatagacat tttttctccg tatctaagtt
    16741 ttcggagctt atgtaatcga gaaatgagtg tctatctatt ttttctatct tcttggcgga
    16801 tagcgtattc gtctgtttta atccagctct gccaaacttt agaatcttta ttttggtgat
    16861 tcatatagtc tataaactca gacataaaac gtttgttttt ctcagctagg tattctgaga
    16921 atatatgacg aaattcatct gaaaaactat catcaagtgg tagtgttaat gccctttcgc
    16981 caaattcgat acttttcttt aacttctcca tatcgctttt aaaaggtgtc acagaaccaa
    17041 ttttagatgt tttgaaacta tctgtaacaa ttttaagatt tgatggagcg tgtgggttgc
    17101 tatcaagtcc cataatataa gcaacggaaa cattaaagta ttttgctaat ttttcagcat
    17161 tatctttttt aggtttgcgg atcccctgat tgtatccaga aagtgtagga taggctatat
    17221 ctgtagcttc gctaatttct gtcaattttt ttccgctatc ttctattagt ttagtaatat
    17281 gattgctcat gagaacctcc tttttatcat tataacacat tttattcttt ttgaataaaa
    17341 aagcttgaca aaaattcaaa aagaatatat aattcaaaat gaataacaaa ttaaatggtt
    17401 tcggagctta tttaatttag aaatgaggtg ttaatttatg tcggaaacta ctttagttgt
    17461 ccagcttcct aaagaattag agaagcaatt acgtgctcat tatgatgaga tgatttcaaa
    17521 tgctgtggca agagtatttg aagataaaga actttataaa cccatggttc gtatgtcagg
    17581 tttgtctagg tggttagatg tatctacgac gacaatccaa aaatggacaa aagaaggaat
    17641 gccaaccatg gtaattgatg gagtgacttt atacgataaa agagcagtaa caagatggtt
    17701 gaagcaatat gaaagatagg tacttgtatg aatggtgttc agtggatcaa gataacaaca
    17761 gatatatttg atgatgaaaa aattcagcta atagaatcga tgccagaagg agatactctt
    17821 attgtaatat ggtttaaact tctggtgctt gcaggaaagc aaaataatag tggaatattg
    17881 agtctaggaa ataaggtata ttacacagaa gagatgcttt caacagtgtt tagacgaaaa
    17941 gctacatcgg taaaattagc tctcagcatg tttgaagaat ttggcatgat agaaatcata
    18001 gatggcgcta ttaccattcc aaaatgggag aaacatcaga atatagatgg cctagaaaag
    18061 attagaaaac aaacaaggga acgtgttgct cgccatagac aaaaacaaaa agcactaatt
    18121 aaaggcgagc cacaactcat tttagactgt aacgttacag taacggatga aaatgagaat
    18181 gtaacgcaag agattaagaa cgagagtaag aataagaaag agattgagaa tatactggat
    18241 aatagttcta gaaagcctga aacttatatt ccacctaaat attattcttt gttagaatcc
    18301 atttcttata aatacaatga tagatttttg tatcctaaca attacacttt aacacatgct
    18361 cagaagatga agataggtga gtatttagct agtggatatg taactagtga tgaagtcatt
    18421 agcatgattg aacggattcc tgaggatgca gcttctcctt tggcgtattt atttaagtct
    18481 atggaaaatt taaagcagga acggatgttg gagtgcaaaa caattgctca tgaaaatgcc
    18541 agaaagaagt atatgataaa tgagtagata tcggactatt ctaaagaaat tttatattac
    18601 tgaagaacaa aatgaaatag cgaataactt aattaaaatg acaaaccatc taagtttttc
    18661 ctcttatgct agaaaaatgt tgtttaaacg ttcgcctatt tatcttcaat ttgattttaa
    18721 atcttatcat gactttatat ttcaagtaag aaggattatc aataacttac gtcagttaga
    18781 aagaatagcg aaacaaagtg aagatttaga taatgtaagg atatttcact gctgtgttga
    18841 gatgatgata ggatatgaaa agaagacaag caaacaagtg aaagaacttg tgaaacgact
    18901 aaataagaaa acgaggtgat aaaattatga gaataaaatc ggtgttgaaa caggtatttt
    18961 tgacagaaga agaaaataaa aaattaaatg attgtatgag gaaggaaaat atttgtaatt
    19021 tttctgagtt tgctagaaaa aaattaatcc gaacagattt gaacattcac aaagtctctt
    19081 ttgaaggttt agttccttta acagaagagt tggaacaggt aggaaagaat atcaattcta
    19141 tagcccgtct tgcaactgta gttgggagaa taagctatga aaataaaatg gatatgtcta
    19201 ttatgatgca aaaaatagtt gacgtgatgg aggaaaaaga tgtttatttt caaaagtagt
    19261 atggataagg attttgatca gatatgcgaa tacatattga aattaaagcg agcagaatta
    19321 tttcttcatg ggattaaaca acaagataaa acgaaggctc gtttgtatca tgcgatgctg
    19381 gaatattacg atgctaacca taaaaaagta agacatatga gaattttaaa ataaggaaac
    19441 gctgttaaaa atttgcagcg ttttttatat atcttcttaa aatatttgta cacacaaatg
    19501 acagtcaaat tgatttttgg gattatttta tcgagaagga aagatttatc ataatatgac
    19561 tttgcgagct cagagtctgt atacacatag tgtatgtact ttttgggatg atttgaattt
    19621 tggggaatcc ccaaacccct gatgaattat acgagcaaaa aaatttggga gtaagtttta
    19681 gaaagaacta ttctacagta tttaaaatct gactttaagt aaatttttta ttatgtgact
    19741 attagtctgt ctcactccgc taggtgcgag acaaaaaaac acccgctatg cgggatgctt
    19801 tttctgttca ccccaaaatt caccttattg ttttagagac tttaaagcaa attcgcctac
    19861 tgtcatagga actacattag aagtatttac ataaatctgt gttgttcctg tgtcactgtg
    19921 tgttagagcc tcagaaatag cttctaagtt cattcctgct tgtttagcag tatgtcgcag
    19981 ttcatgaggt gtagcatgtg ccagctcttt atgttgcttt ctgatacttt tcattttatt
    20041 gtttagatag tcagcatgta aaggcttatt gatgtttcct ctagtgtcta tataagtaaa
    20101 gacaaaccgt ccagatagta tgtcttgcat gctgtttact tcttgtctct tgttttaggt
    20161 tttgagataa tagcgacaac agaagtagtt gtggactatt tttatgaatg tttaaattaa
    20221 tcattagaaa attgttggca gttgagagct ctaagtaaat cattttgata caatttatgg
    20281 tcgcacatag atagtatgtc acaaaagaaa ctgcggctcg ttaaaaattt cattttttca
    20341 gagataggtc tctttttaca tgatttacct attaatatta gtaaatgtta aagataagta
    20401 ttctttttat tttttggcga atgccggcct ttttgccaca aatgagtatc aacatctttc
    20461 gaatggaata gttgacaact ggttttaaga attatactat tgaattgaat agataaggag
    20521 ttgatttgat gcaagagaca atgattgatt acaaacaaaa aatttaccaa gagctatctc
    20581 gcttaacaaa ggggctagga agtgagaagc gtcttgatat tttaaacata ttatcacagg
    20641 gaccaaagac agttgaggga attgcgcata cgacgggtct ctctgttgcc aatacttcgc
    20701 gccaccttca gattttaaaa gaaagtcact tggtggtgac gagtcgaaat ggtaatttta
    20761 tccgttatag cttggcttct gaaaaggttg tccagttagt ccttctgtta tttgccgtcg
    20821 gtgaagaaca gttagcagaa gtcagagcga ttgagtcaga ctatgatgag gcagctggtg
    20881 ttcctcagat tgagctcgct aatgcaattg aattagcagc taagacagat gctctcctac
    20941 ttgatttaag gcctgttgag gagtatgagg cagggcactt gccaaaagct cttaatttac
    21001 caatcgatga gtttgatcaa aaaaaagctc agcttcccaa agagaagacc atcattgttt
    21061 attgtcgcgg gcgccaatgt ggctatgcta acctagcagc acaggattta cagagtttgg
    21121 gctacagtat ctatagtctc aatcgcagtt ttgctgattg gaagtggggc gcatcctctc
    21181 gttcagaact tgactaaggt gaattcctta gtcttttctt ataaccggag actcgtgagc
    21241 aaaatcattg taaaatagat ttagtatgct ataattcaat tattcaataa aa
//
LOCUS       DAVMBH010000035        20206 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVMBH010000035 DAVMBH010000000
VERSION     DAVMBH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.035"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(63..1004)
                     /locus_tag="VYP30_001480"
     CDS             complement(63..1004)
                     /locus_tag="VYP30_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1808459.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VYP30_001481"
     CDS             complement(982..2745)
                     /gene="aspS"
                     /locus_tag="VYP30_001481"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1808460.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            complement(2981..3061)
                     /locus_tag="VYP30_001482"
                     /pseudo
     CDS             complement(2981..3061)
                     /locus_tag="VYP30_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3097..3327)
                     /locus_tag="VYP30_001483"
     CDS             complement(3097..3327)
                     /locus_tag="VYP30_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808461.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(3345..3986)
                     /locus_tag="VYP30_001484"
     CDS             complement(3345..3986)
                     /locus_tag="VYP30_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1808462.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(3998..4732)
                     /locus_tag="VYP30_001485"
     CDS             complement(3998..4732)
                     /locus_tag="VYP30_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1808463.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(4735..4932)
                     /locus_tag="VYP30_001486"
     CDS             complement(4735..4932)
                     /locus_tag="VYP30_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808464.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(4932..5138)
                     /locus_tag="VYP30_001487"
     CDS             complement(4932..5138)
                     /locus_tag="VYP30_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808465.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(5148..5462)
                     /locus_tag="VYP30_001488"
     CDS             complement(5148..5462)
                     /locus_tag="VYP30_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808466.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEFVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(5732..5812)
                     /locus_tag="VYP30_001489"
                     /pseudo
     CDS             complement(5732..5812)
                     /locus_tag="VYP30_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(5803..7092)
                     /locus_tag="VYP30_001490"
     CDS             complement(5803..7092)
                     /locus_tag="VYP30_001490"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1808467.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFATKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(7170..8417)
                     /locus_tag="VYP30_001491"
     CDS             complement(7170..8417)
                     /locus_tag="VYP30_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1808468.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWIVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLDLSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNAYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNMQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(8608..9459)
                     /gene="rgg"
                     /locus_tag="VYP30_001492"
     CDS             complement(8608..9459)
                     /gene="rgg"
                     /locus_tag="VYP30_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1808469.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKFDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKIEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9583..9924
                     /locus_tag="VYP30_001493"
     CDS             9583..9924
                     /locus_tag="VYP30_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1808470.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            9982..10062
                     /locus_tag="VYP30_001494"
                     /pseudo
     CDS             9982..10062
                     /locus_tag="VYP30_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10313..12016)
                     /gene="ilvD"
                     /locus_tag="VYP30_001495"
     CDS             complement(10313..12016)
                     /gene="ilvD"
                     /locus_tag="VYP30_001495"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1808471.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(12249..13181)
                     /locus_tag="VYP30_001496"
     CDS             complement(12249..13181)
                     /locus_tag="VYP30_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1808472.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     NFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSTIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(13178..14035)
                     /locus_tag="VYP30_001497"
     CDS             complement(13178..14035)
                     /locus_tag="VYP30_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1808473.1"
                     /translation="MILSENREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(14039..15385)
                     /locus_tag="VYP30_001498"
     CDS             complement(14039..15385)
                     /locus_tag="VYP30_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1808474.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACIIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(15398..15682)
                     /locus_tag="VYP30_001499"
     CDS             complement(15398..15682)
                     /locus_tag="VYP30_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1808475.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(15686..17716)
                     /locus_tag="VYP30_001500"
     CDS             complement(15686..17716)
                     /locus_tag="VYP30_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1808476.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLTDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            17908..18915
                     /locus_tag="VYP30_001501"
     CDS             17908..18915
                     /locus_tag="VYP30_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1808477.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNGNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            18918..19118
                     /locus_tag="VYP30_001502"
     CDS             18918..19118
                     /locus_tag="VYP30_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1808478.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            19270..19452
                     /gene="rpmF"
                     /locus_tag="VYP30_001503"
     CDS             19270..19452
                     /gene="rpmF"
                     /locus_tag="VYP30_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1808479.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            19468..19617
                     /gene="rpmG"
                     /locus_tag="VYP30_001504"
     CDS             19468..19617
                     /gene="rpmG"
                     /locus_tag="VYP30_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1808480.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(20097..>20206)
                     /locus_tag="VYP30_001505"
     CDS             complement(20097..>20206)
                     /locus_tag="VYP30_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1808481.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         6446 a         4312 c         3546 g         5902 t
ORIGIN      
        1 aacatatata cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa aagtattaat
       61 cactaattat ctatctcaac aaatcttcct agaatatgaa cattttccga gacagagaca
      121 aaggagcttg gatccacttg tgtcataatc tgtttaaatt cattaaactc tgcacgtgta
      181 atgacagtga ttaaaactgc ctttctctcg tgattatagg ttccttctgc atcgtggatc
      241 atggttgctc cgcggtgcaa ttttttatgg attttttcaa ttaccttctc tggatgattt
      301 gtcacaatca tggcctgcat acgcttttgc ttagtaaaga ctgcgtctgt cacacggcta
      361 gagacaaaga tggtaatcat agaataaaga gcgtatttcc aaccaaaggt taaacctgct
      421 atcagcatga tagttccatt taccaagaaa gaaatactac cgacattctt acccgttttc
      481 ttgcgaatag tcaggctgac gatatccgtc ccaccactgg agatattgtt tcgaagagca
      541 aaaccaatcc ccaaacccat aacaacaccc ccaaaaaggg aattgataat gggatcctcc
      601 gtcaaggttg ccacagggac aaactggata aagaaggaac tcatagatac cgtgataaag
      661 gtaaagacgg tgaacttatg gccaatctga taccaagcta agaccatcaa agggaagtta
      721 atggcgtaga agcttagcga aatcggaata tgaaaaccaa accagtgatt actcaaggca
      781 gagataatct gtgccagacc tgttgcacca ctcgaataca catgccctgg ttggaaaaag
      841 aaattaactg ctactgctga taaaaaacca tagaccagag aggccgaaat cttctcatca
      901 tacttttctc gagagatact ttgtaagaca cgtaaaattt ttatctgata agcaaagcgg
      961 cgcagataat agcgccaccg cttaattcgt tttgcttgtt tcatcttctt ctacttgtaa
     1021 gctgagttcc tctagttgtt tgagagcgac tgttgatgga gcttgtgtca ttgggtcagt
     1081 tgccttgttg ttcttaggaa aggcaatgac ttcacggata ttttcttctc cagcaagcaa
     1141 catgacaaaa cggtcaagcc cgatagccaa accaccgtgt ggtgggaaac catagtccat
     1201 ggcttcaaga aggaaaccaa actggtcatt ggcttcttca gctgagaaac caagagcctt
     1261 gaacatgcgt tcttgaaggt ctttttggtt gatacgaagg ctaccaccac caagctcata
     1321 accgttcaag acgatatcgt aagcaatggc acgaacctta gccaaatcac cttctaattc
     1381 gtgagcagtc tcttcctgtg gaagtgtgaa tggatggtgg gcgctcatgt agcggccttc
     1441 ttcttcagac cattcaaaca tcggccagtc aaccacccaa aggaagttga acttatcatt
     1501 atcaatcaag ccaagctctt tagcaatacg tccacgaagg gcacccagtg ttgcattagc
     1561 cacttcaagc gtatccgcca caaagagaac caagtcctta tcttcaagag caagcgctgt
     1621 tgtcaattct tcttggatac cagtcaagaa cttggcaact ggtccgttta attctccatc
     1681 aaccaccttg acccaagcaa gacctttggc accatactgt ttggctactt ccgtcatctt
     1741 gtcgatgtct ttacgtgaat agttgtccgc agctcctttg accacaatcg cttttacagc
     1801 aagtgcttct gaaaagactt taaagtctac acctttgacc acttctgtca agtcctgaag
     1861 caacatgtca aaacgagtat ctggcttgtc agaaccgtaa agagccatag catcatcgta
     1921 tttcatacga gggaacggta gcgttacttc gatgcctttt gtttccttca tcacgcgcgc
     1981 gatcaagcct tctgtaatat cttggatttc ttgctcagta aggaaggacg tttccaagtc
     2041 gacctgagta aattcaggct ggcggtctcc acgcaagtcc tcgtcacgga aacatttaac
     2101 gatttggtag taacggtcaa aaccagcatt catcaagagc tgtttcgtga tttgtggact
     2161 ttgaggaaga gcgtaaaaat gccccttatt aacacgagac ggcactaaat aatcacgcgc
     2221 cccttcaggc gttgacttag aaaggaatgg tgtctccacg tcgataaact ccaactcatc
     2281 caagtagttg cggatagagt gggtcacctt ggcacgaagt ttaagatttt ccaacatttc
     2341 tggacgacga aggtcaaggt aacggtaacg caaacgtgta tcgtcatttg cctcaatgcc
     2401 atccttaatc tcaaatggtg ttgtcttagc tgtgttaagc acaataagag ctgtcacgtt
     2461 taactcaacc gcaccagttg gcaacttatc attggcttgc tcacgcgcag cgacctgacc
     2521 agtcacctca ataacaaatt cgctacgaag gctttcagct gttgccataa cctctgcaga
     2581 tactttttca gggttgataa ccaactgcat gattccttca cggtcacgaa gatcgataaa
     2641 gatcaaacca ccaaggtcac gacgacggcc aacccatcct ttcaaggtta tttcttgtcc
     2701 gatgtgttcc tcacgaacac gaccagcata catactacgt ttcattattt ctctcctctt
     2761 ttattctgtt actattttac cataaaagcg caggctcttc atgaaaatca tcagaaaagt
     2821 ttgccagtct ttaaaagtca ggtgaaagcc ctaaaaatta gcgctaatac tcttcgaaaa
     2881 tctcttcaaa ccacgtcagc gtcgccttac cgtaggtatg gttactgact tcgtcagttt
     2941 catctacaac ctcaaaacca tgttttgagc tgacttcgtc agttctatcc acaacctcaa
     3001 aacagtgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt ttcattgagt
     3061 ataatacaaa aatccgatga acttcaccgg actcttttat tttgaatttt tgcctgcttt
     3121 acgcttttca gcgatttcgg ctgcctttcg aggcaagaca atttccgtta tgtaagccgt
     3181 cccaaaacgc agtacacctg caataggagc aaagacaact gctagatagt tatagaagaa
     3241 atcgcctttg aaggcataag ctagcgctcc aatgatgaaa aatagaacga ctgcctgaat
     3301 cactgctaat aaaattactc gtttcatgtg acctcctgac tctattatag catgagaatc
     3361 atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa tactgtagac cagacctttt
     3421 ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa aatagacaaa aaattgttgc
     3481 acatcacctg gaaaatgaat caaggcaaat agaagactag ataccagaag aaaaatcagg
     3541 gttcgtttac tattgtcctg cttaggaaag agatagcgtg ctaacatccc tctaaaaaca
     3601 atctcttccg tcaaaggagc aaaaataacc acagcaaaga atgagaaaag tggttgagac
     3661 aaggtcaagt ctgtcgctat ttgctgattt actgaaggat catctggcaa gaagaattga
     3721 acgaccagag ataagaacca aaccaagaca ggaagccaaa taaatcgatt aaagccgctc
     3781 ttctcaatat gaacaggagc cttctgatac catttgtaaa tgccgtacac atatactcca
     3841 gccaaggcca catagagtag agtaacagca tagggtgaag cgcctaaagc aagcgacgca
     3901 gtcgcgagcc cctgaataaa gccatagata aataaaaagg atagaagggc tagaagaatc
     3961 cagccaaggt ttttaagtaa tttcatagat aactccttta tttgaaataa cgttttacca
     4021 taggtaactg catcacattg atataaacat ggatggctcc tacaagcaag aaagctagta
     4081 actgaatctc tcctgtcaag aaagaaatga taataagaaa aatatataag gctggtaaga
     4141 catattggtg taattggaat aaaattcgaa aactctgttc caaattagcc tgacgctccc
     4201 cttcatcata agaatttata tagttcaaga catcctttgg tgtagcgaaa aattccaaat
     4261 caaactgacg aacaatcgca atggttttaa aaagagattt ttgagcgact aagaatacca
     4321 caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt atgcaatata atcacctcac
     4381 ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt aatattaaaa gcaatggttc
     4441 caaactcaag attccgatac atttgcacat aataggtttc attcagatcg tcatccattt
     4501 cctcttgata caaggaatga aattttctgc ttttctttaa gaaattgaaa gtcaaaaaca
     4561 tactaatgaa acctatcagt aaacaaatag ctgatatcca tggcatcaag gcttttacat
     4621 ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat ccctacaaac atgcccaaga
     4681 acccccccaa gacaatagac atcaaaaata acaatctacg tttctttttc atattcattc
     4741 tcctttttca cttgctagat ttttggattt cttttcaatc cattcagtta ctgggatgag
     4801 agcaaagtag acccaaacaa attggtcgct ttgataggga ttaaaccagc ttaggtccat
     4861 cccaatcagt agaaatacgc tgactaataa agctatgacc actacataat aaatcacttt
     4921 atacttgttc atcactcgtc ctcctccaaa cgaaataccg attcgactgt ttcgttgaaa
     4981 atttgagata ttttcagggc aatgataatg gatggggtgt actcatcccg ttctagtagg
     5041 ctaatggtct gtctggaaac ccctgccagt ttggctaggt cggtttgatt gagaccatcg
     5101 cgagctcgaa gctcttttag acgatttttt agttgcacgt tacacaccta ctctccgtca
     5161 aattcaacgg tttggatatc ttcaatacgt tgcaacttga atttttcttt tcccgtatta
     5221 tcaacactac gtagtttgac ccattcctca tcaacatcca caaattccca gttatctggc
     5281 ccaatataca ctcccgttat aattggttcc tttccaatca tttcttgtaa taatctcgac
     5341 atttctgcgt ttcctttctc ttttcgctca agttttttga ttttattctc tagtttcttg
     5401 atttttttag aattattaga ataaaagaaa atcataaata gtataaatcc tagtacccac
     5461 attataactc ctttctgctt cctatttctt aacttgaatt cattgtaaca tatctttttc
     5521 tttttgacaa gtatagctgt caaaaagttt atgatttttg tcattttgca aaagaaaaag
     5581 gtcaggagta agttcctgac cactttatct atcattaata ctcttctaaa atctcttcaa
     5641 accacgtcag cttcaccttg ccgtaggtat ggttactgac ttcgtcagtt tcatctacaa
     5701 cctcaaaacc atgttttgag ctgacttcgt cagttctatc cataacttca aaacagtgtt
     5761 ttgagcaatc tgcggctagc ttcctagttt gctctttgat ttttattgag tataaaatcc
     5821 tagtttttca aagatttctg aaaagttttg gctgattgtc tcaagtgaca cttgcacttc
     5881 ttctcgggtt tggttgttct tgaccgtcac ttgtccgctt tcgacttcgc tctctcccag
     5941 ggtgatgagg gtcttagtcg caaagacatc ggctgacttg aactgagctt tgagcttacg
     6001 gttgaggtaa tcacgctctg ctttgaaacc ttgttggcga agggcttgga ctagttctag
     6061 ggctttgaca tttgctccat cacccaagac tgcgatatag acatctaggg cattttcgat
     6121 agggagggcc acgccttgtt tttcaaggat gagaagcaga cgctctacac caagcccaaa
     6181 accaaatcca gcagtttcag ggcctccaaa gtaagcaacc aaaccatcgt agcgaccacc
     6241 cgcacagact gtcaagtcat tgccctcaat ctctgtgata aactcgaaaa tggtgtggtt
     6301 gtagtagtcc agaccacgca ccatattggt atcgatgatg taatctactc caagattttc
     6361 caacatctga cgcacagcat caaaatgagc ttggctttct tcatcaagaa agtccaagat
     6421 agacggcgca ttctctactg ccaccttgtc ttctttttcc ttagagtcca agacacgaag
     6481 aggattttcc tccaagcgac gttggctatc cttagacaag gtctccttga gcggtgtcaa
     6541 atagtcaatc aaggcttggc ggtaggctgc acggctctca ggatttccaa gagtgttgag
     6601 gtgcaatttg acaccttgaa taccgatttc cttcaaaaaa tgggctgcca taacgattgt
     6661 ttccacatcg gtagctggat tgctagagcc aaaacactca acaccaatct ggtggaattg
     6721 gcgcaagcgc cctgcctgtg gacgctcata acggaacata ggtcccatat agtagaactt
     6781 gcttggcttt tgcacttctg gggcgaagag tttattttcc acataggaac ggacaacggg
     6841 cgcagttcct tctggacgga gggtaatatg acggtcaccc ttgtcataaa aatcgtacat
     6901 ttccttggtt acgatatccg ttgtatctcc gacagagcgg ctgataacct cgtaatgctc
     6961 aaaaataggc gtgcgcactt ctgcatagtt atagcgcttg aaaatctcac gggcaaagcc
     7021 ctcaacgtac tgccacttag cagactcagc aggtaaaata tcctgcgttc cttttggttt
     7081 ttgtaatttc atagggaatc ctctttaaac ttaatagtct tattttacca taaatagagg
     7141 gattaaaaca gtaagaaaaa aattaggatt tagatatcat ttttgagatt aagaattgtt
     7201 aaaaaaatag ctagcaagga aagaccaaca aatagcatcc aagtcaactg catgttccat
     7261 acggctacta gtgaaaaaca agctgttccc acaggtatgg ataaggtaaa caatagacct
     7321 aaaaaattac tagtacgagc tagaacctct ggagctagat ttttcatgag catggcacta
     7381 atctttggtt gaactttacc agacacatac agagtaaaga agagaaatag caaaccaagc
     7441 acgacttgat tgaataaatt agccaaacca actagactaa gtcctacggt cgcccacatc
     7501 atcaatctag gcaaggactg cttcccaaaa taagcattgc ccgtaagact actgatgatg
     7561 attgctacta aaacacagaa ttgattgata aatagtgcct ctgtataaga aaaattcaag
     7621 agagaatggc tcaaaaagaa gatattataa attccaccca aagcgccacc caaggaatta
     7681 ataagcaaga cagcaaagag cataaaacca aagtttttct gtccactttt aagaaaaacg
     7741 agacgtaaat ttcggtaaat tgttaggaac tggtctttga tagaaagctt ctcatttttt
     7801 aagttttcac catcagcaga tgacattgac aggctcaatt tgctttttcc taaaaagagg
     7861 atagtggctg atactaggaa aaagcaggca ttgattcccg caacgagaga aaaattgttg
     7921 accgatagat ctaagagcca gactccgaaa gcttgaccac caatagctga aatataggtg
     7981 atgaactgtg aaaaagaata agcctccatc agatcatctt cagctacttt ttccttaata
     8041 agaggcatac gcaggccacc tgcaaaatca ctgatgatat cactaatgac attgatcaaa
     8101 cacaggctag aaaaggcaaa gagactagct tgctgaacaa ctagggctgc tagaaaaaat
     8161 agaaccgcct gaaacaaacc gctatagact atccatttga ccttgtccct cgtgtaatct
     8221 gcccgaatcc ctgcaaaaac tgtaaagaag gtcggaagaa tcatgacaat attcgccata
     8281 gcaacagcaa aagatgcttg tgacaaggtc gatgcataga cgataaagac caggttgaaa
     8341 atcgaagcac caaaagcatt gaagaagcgt gataaagtca aaattctata agctggattt
     8401 ctaaacaata gtttcataga taatctccct ccttgttcta agttctacat caagaatagc
     8461 tttagtatag cacttatgaa tttgcgaaac gattcttttg aatatatgca acaaacaaaa
     8521 tgagcaaaaa aacgatagaa cttttgtaat gacctgagag agggcaacag ttctatcgct
     8581 tcaaattttt tcttggtttg cagatactca acattcggtc gtatttctat agtattcggc
     8641 agatttatta cagccaagca tctcaaaaat acggacagca tcctctatct ttttctgacc
     8701 ttccttgact ctaccttgct tgctatcaag gagaccttct gcccacagat aaacaattcg
     8761 gaaataggtc tcattttcct tgtagaaatg ctcttcgata acacgtttaa aataataggc
     8821 attggtaaat tcttcacact caatactagc taaaaagcca ttcaatagta tagtatgaaa
     8881 aaggtttcga ttgccagaca tttccattag aaaatcgaat ttacgtacca tttctcgtac
     8941 atatctagta aaaagagaaa cggataaaaa tggagaactg actgaaaata aattgagttc
     9001 atagattccc cagatctcgg tagaaaacaa ataatcatga aggacttttc cttcctctgc
     9061 tgttaagtct accctttcat ctatgctctt catataagac ttgatcataa tggcatttag
     9121 aatatgtttc tgtttgttgt gagaatgggc atgcttttga tactccctgc gatataagtc
     9181 ctcaagaggt gctatattct ttggttccaa gacatctgta atttcttttc tcaactcaga
     9241 atctgtatca tactggaaac ctctcgccag aaagaggatc tcctccacac tggcagatat
     9301 attttccaga gcaaatagaa acttttccac cgaaagctca ctctgacctg tttcaaaacg
     9361 ggacaacata gacggcgaaa attgtcctcc ggttgcttgt ctcagtgaga tatttcttga
     9421 ttctcgtaat tgtctaaaga cttttccaat ctgctccata gacttcccct tgattccgta
     9481 ttttcttcat tttatcatat ttttcagaaa attcatcaaa aacttgccaa attgtcagaa
     9541 ttatgagaaa atagaggata tttatcacgt ggagggactg ctatgagaga cgatatcaaa
     9601 atcaatgacc gtgctttggc cttgcaagac caaattatcg aaaaactaga gaaagttttt
     9661 gatacagatg tggaattgga tgtttacaat ctaggtctga tttatgaaat caatctggat
     9721 gaaacggggc tctgcaagat tgtcatgacc ttcaccgata ctgcctgtga ttgcgccgaa
     9781 agcctaccta ttgaaatcgt ggcaggtctg aaacaaatcg agggtatcaa agatatcaag
     9841 gttgaagtta cctggtcgcc tgcttggaaa atcacacgaa tcagtcgcta tggccgtatt
     9901 gcccttggat taccacctcg ttaagcaggc caatcacttt taaagatgaa aaaagcaagc
     9961 cgaaaatggc ttgctttttg atactcaatg aaaatcaaag ggcaaactag aaaactagcc
    10021 gaaggttgct caaaacactg ttttgaagtt atggatagaa ctgacgaagt cagctcaaaa
    10081 tactgttttg aggttgtgga tagaactgac gaagtcagct caaaatactg ttttgaggtt
    10141 gtggatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgtgga tagaactgac
    10201 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat
    10261 acctacggca aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt
    10321 tacctgactt gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga
    10381 tgtgggcata tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct
    10441 tgcgtttttc aagttcttct tcggatacag ccatggaaat ttctttggta tcttggtcaa
    10501 ccgtaacgat atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag
    10561 ctatatgtcc aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg
    10621 ccaccttatc tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca
    10681 taccaggacc acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt
    10741 catctgtcag aacggcctga atcgcatctt cttctgagtc aaagacctta gctggtccaa
    10801 cgtgacgacg cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc
    10861 cgttcaagat gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt
    10921 tttggcctgg agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac
    10981 atgtgatgcg atctccgtga aggaaaccat ttgccaacaa gtacttcata accgcaggga
    11041 caccaccgac ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca
    11101 agtgaggcac acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg
    11161 catgggcaat ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta
    11221 cagtaatagc atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt
    11281 ccaacatctt aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt
    11341 cagctgggtg agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca
    11401 tggtattagc agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa
    11461 gacgtttcac gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga
    11521 cagaaaccaa gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg
    11581 cgaaaatagc tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt
    11641 cacagccacc gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg
    11701 agtccgcgat gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga
    11761 tcccgtctgc tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac
    11821 cttctttagc cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc
    11881 aagtcgaaat cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac
    11941 gaagcatagc acggttaggt gatttaacca tgctgtcata gatgctactg cggtgacgtt
    12001 tatctaattc agtcatctta tccctcccat ttcagttttt actattatag cacaattttc
    12061 gcatgaagaa cagaataaaa atcttgaatt ttcagaaaat tctatacaca tgtgaaatat
    12121 ttaaaattaa aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt
    12181 aatccgcttt ctttaaataa cgtactgtaa tttttacaga aattctttca gataagtgta
    12241 tttaacatct atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc
    12301 aaaccatact cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca
    12361 cccatccgat gaatttttgt tattccatca tcagagaata attcacataa agcactgcca
    12421 attccaccta tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt
    12481 tttatctgtt ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct
    12541 aatttagaca gttcatctgc aactcgaata cttggagcaa ccattatacc agaagcaacg
    12601 attacaagat cttccccatg tcttaactca atgtagcctt tagaaaaatc ttctccacct
    12661 tgatacacag gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct
    12721 aatgtctggt tcaatatttc acgaaattgg atatcatcag ttgcttcaaa aatggtcgat
    12781 ttaggaatta aacgtaacaa tccaatttct tcaaatggca tatgtgtccc accattcatt
    12841 tctgcagtta ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga
    12901 gaaataaata attgatcaaa tacccttcgt gaagcaaaag gaccaaatgt atgaagataa
    12961 ggtctaaacc cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc
    13021 ccaacattca cataacggtc tccaaagttc ttttcaagat tatgagtagc catcgaactt
    13081 gacaaatcgg cttctaagac tactatatca gaataacttt gattagcctc taaaaggaag
    13141 tctctatata catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct
    13201 gacttaatct ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat
    13261 gatgattgga tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata
    13321 caatgcactt aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt
    13381 ctctaatatc tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta
    13441 cgaaatcacc tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat
    13501 caacaaatac aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac
    13561 attgtccctc atttaactca ccatctccaa caatagcata agtataaaag ggactctttc
    13621 ttattctctg accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg
    13681 ttgtcatatc tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat
    13741 ttgtatttaa agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt
    13801 atagagctgg tcctccatga ccttttgata atatgaaata atctctatct cgtgctgcaa
    13861 atatttctgg agtcattggc attatttcac cataaagcac tgctaaaact tctacgatag
    13921 acagacttcc tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc
    13981 ggatgttagt cgcaaatttt cttaactcat cttctctatt ttcacttaaa atcatccctt
    14041 actcctcctt tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa
    14101 gaacaagacc aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa
    14161 ttcctgatag accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca
    14221 aaactggcat taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa
    14281 tagtggctcc acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga
    14341 agaaatgagg cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattgcca
    14401 tacttactaa accaccaata aaactagaga taaatccaat tagaactgca ttgggtgcat
    14461 aagtataaac aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa
    14521 tacctttaaa ggctggaaca atttcaccca aaataaggcg aacacctgct aaaataacaa
    14581 atacccctgc tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac
    14641 tactgatttc tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa
    14701 ctgccataga taaagtgata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa
    14761 atttaatgtc ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca
    14821 accaatatcc caaagaactg aaatgaccta aagccacctt gtcatttcca gttaattgaa
    14881 ccatatattt ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc
    14941 ctagtaagat gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaattatac
    15001 atgccatata tagagtgtgg tgccctgtta aaaagatata tttaaatcga gtaaaacgag
    15061 cgattaagat attgaacacc atgcctgcaa acataatcat tgcagtagct gagccatatg
    15121 ttgttaaagc tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag
    15181 catgctcaaa catggtacca aatggattta aagaattttg tacaattcct gcaccaccag
    15241 atacaactaa gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct
    15301 tcttctgaag aactaatcct aaaattgcaa ttaaagctac taaaatagct ggtgtactaa
    15361 caatatccaa tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac
    15421 aaagtttagt aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa
    15481 catctccaag atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagcag
    15541 catttggatc tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat
    15601 cactcaatac agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac
    15661 aagctgtacc aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat
    15721 catagttttt tgatgaaatt aaagtttgaa catgattttt atctcttaaa attgttgtta
    15781 aatgtgacaa agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc
    15841 ttacctcttg ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca
    15901 ttcctatttc attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta
    15961 aattaataaa aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctccg
    16021 ttatcttatc ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta
    16081 atttttgcga actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa
    16141 tttcctttct atcatttttt tgataaagat aattctttaa cgccaatctt aattccaatt
    16201 cttgtgtaat aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc
    16261 catactctaa attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt
    16321 cagtcatcat aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa
    16381 aaaccatatc atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta
    16441 taaactcaat ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa
    16501 caccattagg acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct
    16561 ttaaataacc tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt
    16621 caatagcgtc catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat
    16681 gttctttaac atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt
    16741 aagccggtat aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta
    16801 acaaagaaat atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg
    16861 gagcaacatc tacttcacct tcaaagcaac ttgataataa aactgtgata tagcgataat
    16921 catcctcaga aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag
    16981 tggttatatc ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat
    17041 ccctttgata cctacacaga atgaatacta aaccgaaaag gcaaactttt aattgattaa
    17101 caataggtac tagctgtagc ttctcataat aatctttaac tacctgattt atcaaatcat
    17161 aagttaatga atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg
    17221 attccagcaa ctcactaacc atttgaaaag ctaaacggtg cttattccac tctgaaccgt
    17281 gtaaagtata accttttgct ctactgtacc ctagctccaa atcattatct aacataatct
    17341 ttcttaatga ttgaatatca gttaaggttg tattcttact tactttcaaa aagtcttggt
    17401 aatgattatt cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc
    17461 gagtcgactt tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg
    17521 tacgatttga taaactatag cgaccttgtt ttttatccag cactatccct ttattagcta
    17581 gataaggcac taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa
    17641 cagataattc atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg
    17701 ctctataatc aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga
    17761 ataaaagagt atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa
    17821 gtttttagtg attatttttc aactttctat tgactttata aattaaagtg atatcattta
    17881 gatatcaaat aacaggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat
    17941 ggtgtattcg cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata
    18001 atgggggttg gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt
    18061 gcaggtctag ctcatgctgg tttaaaagtt gtcaaacctc aggaagctct ggttctgaca
    18121 ctctttggta attatacagg taccatcaaa gaacctggtt tttactttgt caatcccttc
    18181 agcgtagcag tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca
    18241 aaatctcctt ttttaggagc taaatcatca aatggcaatg atgtaaatct tgaaattggc
    18301 aagaaacaca tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat
    18361 tgcttaggaa accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct
    18421 aaggcagtct tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc
    18481 ctccgtaata ttgtccgcat ctatccttac gatgtgtctc ctaatgtgga tactacgggt
    18541 gacgggcaag cagatgaagg tagtctccgt ggctctagtg aaattgtagc taaccgtatt
    18601 cgtgaagaaa tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc
    18661 acttacctag cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct
    18721 gccattattg atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca
    18781 ctagaacggc tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg
    18841 gtttcaaatc tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca
    18901 ggaagtcttt actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa
    18961 caaagttata cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc
    19021 aaatcgaata tctcctcaca gagtgtgtca agcaacggaa aaaagacgga aaatacgtat
    19081 cagaaaccat tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt
    19141 cggataggag aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt
    19201 gttatcctag tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga
    19261 gaaatcaaaa tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt
    19321 acacactaca aagtaacagc tccatctgta aactttgacg aaactactgg agattactca
    19381 cgttctcacc gtgtatcact taaaggatac tacaaaggac gtaaaatcgc taaagctgca
    19441 tcagctgaat aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa
    19501 tctggtgaac gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa
    19561 ttgaagaaat actcaccaaa acttcgcaaa cacgttgtgt ttacagaagt gaagtaagca
    19621 ttcaatacga atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt
    19681 tcactatatt gcaagagaaa tcattcgaat gactacattt tttgaaataa gaatacggat
    19741 tcggacgatt aaaagtaaga gaaactcaaa tgtaagttgg ggttcctttt ttgtatattt
    19801 ttcaaataac gcctctacac tatttgtagc aaattcacca actacagttg catcttagtt
    19861 aaaataagtt agaatatgta agtgagtacc agatatacca agacatcgtc accatctaag
    19921 gtatattcaa aatacaaaag ttgaccaact agatttctga atatccttat atatccattc
    19981 ttaaaattgg tttaaatagc gtagtctttt aaactagttt tgagaatcca aaaaatcttc
    20041 ctacatatgt aagaagattt tttagttcag aatgattaga tttagctaat ggatacctat
    20101 cctacccact caccgttagc attgactcga tagccatcgg gtgtagtcgt gtttactaat
    20161 aaatctcctg aattataggt atagtaccat ttaccagaaa ctgtaa
//
LOCUS       DAVMBH010000036        18688 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVMBH010000036 DAVMBH010000000
VERSION     DAVMBH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18688
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.036"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            83..547
                     /locus_tag="VYP30_001506"
     CDS             83..547
                     /locus_tag="VYP30_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1808482.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            704..1129
                     /gene="lacA"
                     /locus_tag="VYP30_001507"
     CDS             704..1129
                     /gene="lacA"
                     /locus_tag="VYP30_001507"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1808483.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1160..1675
                     /gene="lacB"
                     /locus_tag="VYP30_001508"
     CDS             1160..1675
                     /gene="lacB"
                     /locus_tag="VYP30_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1808484.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGIRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1686..2615
                     /locus_tag="VYP30_001509"
     CDS             1686..2615
                     /locus_tag="VYP30_001509"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1808485.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLTKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2617..3597
                     /gene="lacD"
                     /locus_tag="VYP30_001510"
     CDS             2617..3597
                     /gene="lacD"
                     /locus_tag="VYP30_001510"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1808486.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3831..4667
                     /locus_tag="VYP30_001511"
     CDS             3831..4667
                     /locus_tag="VYP30_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1808487.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4703..5020
                     /locus_tag="VYP30_001512"
     CDS             4703..5020
                     /locus_tag="VYP30_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1808488.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5020..6711
                     /locus_tag="VYP30_001513"
     CDS             5020..6711
                     /locus_tag="VYP30_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1808489.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6920..8326
                     /gene="lacG"
                     /locus_tag="VYP30_001514"
     CDS             6920..8326
                     /gene="lacG"
                     /locus_tag="VYP30_001514"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1808490.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDHENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGKKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8471..8635
                     /locus_tag="VYP30_001515"
     CDS             8471..8635
                     /locus_tag="VYP30_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1808491.1"
                     /translation="MESLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEWDTISF
                     DSDFMPFQQS"
     gene            complement(8914..9675)
                     /locus_tag="VYP30_001516"
     CDS             complement(8914..9675)
                     /locus_tag="VYP30_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1808492.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9857..10819)
                     /gene="nrdF"
                     /locus_tag="VYP30_001517"
     CDS             complement(9857..10819)
                     /gene="nrdF"
                     /locus_tag="VYP30_001517"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1808493.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11007..13166)
                     /gene="nrdE"
                     /locus_tag="VYP30_001518"
     CDS             complement(11007..13166)
                     /gene="nrdE"
                     /locus_tag="VYP30_001518"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1808494.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13247..13465)
                     /gene="nrdH"
                     /locus_tag="VYP30_001519"
     CDS             complement(13247..13465)
                     /gene="nrdH"
                     /locus_tag="VYP30_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1808495.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13816..14079
                     /locus_tag="VYP30_001520"
     CDS             13816..14079
                     /locus_tag="VYP30_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1808496.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14085..15818
                     /gene="ptsP"
                     /locus_tag="VYP30_001521"
     CDS             14085..15818
                     /gene="ptsP"
                     /locus_tag="VYP30_001521"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1808497.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16073..18523
                     /gene="phtA"
                     /locus_tag="VYP30_001522"
     CDS             16073..18523
                     /gene="phtA"
                     /locus_tag="VYP30_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1808498.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
BASE COUNT         5921 a         3382 c         3838 g         5547 t
ORIGIN      
        1 tgctggtatt atcaatcata aactagaatt ctagttttgc aggaagtcta ataaagaaac
       61 tagcaaggtc aggccttact ttattggtgg acatccagga tttaattgtc ttctacttga
      121 tgatgaagtc tatgaagatt attatctaga gtttgagaaa gaagagattt gctctgttcc
      181 acgtcctttc ccagaaacag gtatgttgga tttccaagat agaagtccat ggctagaggg
      241 acaaaaagaa atagatctta gttatgatct tttcagcaca gatgcagtga ctttggatga
      301 attgcaatct cgaacaattg cccttcgttc tcttaaacat gataagggat tgaaagtgca
      361 ttttgcagaa tttccaaacc tcatcatctg gtcaactttg aacaagggac ctttcattac
      421 ctttgaacca tggtctggct tgtcaacatt ccttgaagaa ggagatcatt tagaagataa
      481 gaagaatgtt tgtctcttag aagccaatca ggttgaagaa ttagggtttg agatagaagt
      541 tttataaaaa agcaaaaaat aaataacaaa aacaaacaca aactgttgac ttcttcaaac
      601 aatagtagta tattatgttt gtgaggacta attgactgtt ttttaaagac agccaataca
      661 ctgctggaat ccagcataga aaaaataaaa aggagtatac aatatgtcta ttgttatcgg
      721 tgcagatgct gcaggtttga gattgaaaga agttgtgaaa gacttcttag aaaaagaaaa
      781 cttccacctt gtggatgtta cagctgaagg tcaagacttt gttgatgtga ctctcgctgt
      841 tgctgcagaa gtaaacaaag aagaacaaaa ccttggtatc gtgattgatg cttatggagc
      901 tggtccattt atggttgcaa ctaagatcaa aggaatggtt gctgcagaag tatctgacga
      961 acgttcagct tatatgactc gtggccacaa caactcacgt atgatcacta tgggggcaca
     1021 acttgttggt gatgaattgg ctaaaaatat cgctaaagga tttgttaacg gtaaatacga
     1081 cggtggtcgt caccaaatta gggtcgacat gttgaacaaa atgggctaat tagattatag
     1141 taagaaaggt aagttaaaaa tgagaattgc aattggatgt gaccacatcg taacagatga
     1201 aaaaatggcg gtttcagaat ttttgaaatc aaaaggatat gaagtcattg actttggtac
     1261 ctatgaccat acacgtactc actacccaat ctttggtaaa aaagtagggg aagcagtaac
     1321 tagtggtcaa gctgatctcg gggtatgtat ctgtggtact ggtgttggta tcaacaacgc
     1381 tgtaaataaa gttccaggta ttcgttctgc cttggttcgt gatatgacaa cagcccttta
     1441 tgctaaagaa caattgaacg ccaacgttat cggttttggt ggtaagatta ctggtgaatt
     1501 gcttatgtgt gatatcatcg aagctttcat tcatgctgaa tacaaaccat ctgaagaaaa
     1561 caaaaaattg attgcgaaaa ttgaacacct tgaaagtcac aatgctcaac aaacagacgc
     1621 aaacttcttc actgaattcc ttgaaaaatg ggatcgcgga gaataccacg actaagaggt
     1681 aacctatgat tttaacagtt acaatgaacc catccattga tatttcctat cccttggatg
     1741 agttgaagat tgatactgtc aatcgtgtgg tggatgtaac caaaacggct ggtggtaagg
     1801 gactcaatgt tacccgagta ctttcagaat ttggcgattc tgttcttgct actggtttag
     1861 tgggtggcaa acttggtgag tttttggttg aacatatcga taatcaagta aagaaagatt
     1921 tcttctcaat tcagggagaa actcgtaact gtatcgctat tctccacgga gacaaccaaa
     1981 cagaagttct tgaaaaaggt cctgaagtat tggaacagga aggtcaagac tttttggaac
     2041 atttcaaaaa actcttggag tcagttgaag tagtggccat ctcaggtagt ctgccagctg
     2101 gccttccagt tgattactat gcgagcttgg tagaacttgc taatcaagct ggcaagcctg
     2161 tagtcttgga ctgctcaggt gcagcacttc aggctgttct tgaatcaccc cataaaccaa
     2221 cagtcatcaa accaaataat gaagaattgt ctcagcttct tggaagagaa gtttctgagg
     2281 atttggatga attaaaagaa gtacttcaag aacctttgtt tgcagggatt gaatggatta
     2341 tcgtttcact tggtgccaac ggtacttttg ccaaacatgg tgacactttc tacaaggtag
     2401 atattcctag aattcaggtg gtaaatcctg ttggatctgg agactctact gtggcaggaa
     2461 tttcttcagg acttcttcac aaagaatcgg atgcagaatt actcaccaag gcaaatgtcc
     2521 ttggtatgct caatgctcaa gaaaaaatga ctggtcatgt caacatggcc aactatcaag
     2581 ttctatatga tcaattaata gtaaaagagg tataaaatgg ctttaacaga acaaaaacgt
     2641 gtacgcttag aaaaactttc tgatgaaaat ggtatcatct cagctcttgc atttgaccaa
     2701 cgtggtgctt tgaaacgcct catggctcaa caccaaacag aagaaccaac tgtggcccaa
     2761 atggaagaac ttaaagtctt ggtagcagat gaattgacta aatacgcttc atctatgctt
     2821 cttgaccctg agtatggact tccagcaact aaagctcttg atgaaaaagc tggtcttctc
     2881 cttgcttatg aaaaaacagg ttatgacaca acaagcacaa aacgcttgcc agactgcttg
     2941 gatgtctggt ctgcaaaacg tattaaagaa gaaggtgcag atgcagttaa attcttgctt
     3001 tactatgatg tagatagctc agacgaactc aatcaagaaa aacaagccta catcgaacgc
     3061 atcggttctg agtgtgtggc tgaagatatc ccattcttcc ttgaaattct tgcttacgat
     3121 gaaaaaattg cggatgcagg ttctgtagaa tacgcgaaag taaaaccaca caaagttatc
     3181 ggcgctatga aagtcttttc agacccacgc tttaacattg atgtcttgaa agttgaagtt
     3241 cctgttaaca ttaaatatgt tgaaggcttc gctgaaggtg aagtagttta tacacgtgaa
     3301 gaagcagcag ccttcttcaa agcgcaagat gaagcaacga acttgccata catctacttg
     3361 agtgctggtg tatcagctaa actcttccaa gatactcttg tatttgctca tgaatcaggt
     3421 gcaaacttta acggagttct ttgtggccgt gctacatggg cagggtcagt tgaagcttac
     3481 atcaaagatg gtgaagcagc agctcgcgaa tggcttcgca caactggatt tgaaaacatt
     3541 gatgagctca ataaagttct tcaaacaaca gcgacttcat ggaaagaacg tgtgtaagaa
     3601 agtcctccta gtttaggaac atgaatctaa aaaaatttaa aaaaagttgt atgtaaaggt
     3661 ttacaaaata acttacttgt gctatactta aatcacaagt taatacaagg tgagtgttac
     3721 taagtaatat taggcatgat cacaggtgaa ttagaaatca gctgattttc tagttcattt
     3781 gtggtcattt tttgtactta tataccttta agatataaaa ggaggttgac atgtatcgaa
     3841 ttctaaatcc aatgaatcac aatgtctcgc ttgtcagaaa tgataaggga gaagaggtga
     3901 ttgtaattgg taaggggatt gcattcggaa agaagaaggg ggatttgatt gctgaaaatc
     3961 aggttgagaa aatctttcgg atgaagaccg aagagtccag agaaaacttt atggctcttc
     4021 tcaaagatgt tccgcttgat tttatcacag tgacctatga aatcattgat aagctatcaa
     4081 agaaatatca ttatccgatt caagagtatc tctatgtaac cttgacagat catatttact
     4141 gttcttatca agctctaact caaggaaggt acaaggatag taatctgcca gatatttccg
     4201 ctaagtatcc tgtcgctttt caaatcgcaa atgaagcttt tgaaatttac cgtcagaagc
     4261 tagcagatca ttttcctgag gacgaaatta ttcggattgc ttatcatttc attaatgctg
     4321 aaggtgaaaa tgaagtggaa cttgtggagt cgattgataa gaggaaagaa attctcagga
     4381 atgttgaaga agttttaacg gactatgcaa ttcaacgaac taaaaagaat aaccatttct
     4441 atgatcgctt tatgatccat ttgaattatt tcttggatta tttagacaga tctagagatg
     4501 ataaccaatc acttctggat atggaagatc atattaaaca atcctatcca aaagccttcg
     4561 agattggttc caagatctat gatgtgatta cgcaacatac gggtcttgat ttgtataaaa
     4621 gtgaacgagt ttatctagtt ctacatatcc aacgtttatt gtcataaaaa tttatttaaa
     4681 actatataag gagaattcta tcatgaatag agaagaagta acattgttag gttttgaaat
     4741 cgtagcctat gctggcgatg ctcgttcaaa actattggaa gccttgaagg ctgctgaagc
     4801 tggtgatttt gaaaaagcgg acgctctggt agaggaagct ggtagctgta ttgcagaggc
     4861 tcaccacgcg caaacaagtc tattgactaa ggaagcttca ggtgaggact tggcttatag
     4921 tgtaaccatg atgcatggcc aagaccactt aatgacaact atcttgttaa aagatttgat
     4981 gcatcattta attgaactct acaagagagg agttaaataa tgaataaact aattgcattt
     5041 atcgagaaag gaaagccttt ctttgaaaaa ctatctcgta atatctatct tcgtgctatt
     5101 cgtgatggtt tcattgcagg tatgcctgtt attctcttct caagtatctt tatcttgatt
     5161 gcctttgtac caaactcatg gggctttaaa tggtctgatg aagttgtagc ctttctgatg
     5221 aaaccttata gctattctat gggtattctg gctctcttgg tagctggtac aacagctaag
     5281 tcattgactg actcagtaaa ccgtagcatg gaaaaaacca atcaaatcaa ctatatgtca
     5341 acattgttgg cagcaattgt tggtttgttg atgttggcag ctgatcctat cgaaagtggt
     5401 ctagctactg gattcttggg gacaaaaggt ttgctttcag ccttccttgc tgccttcgtt
     5461 actgtagcca tctataaggt ttgtgttaag aacaacgtca ctattcgtat gcctgacgaa
     5521 gttccaccaa atatctcaca agtctttaaa gatgtgattc cattcactct ctcagttgtt
     5581 tcactttatg ctcttgattt actagctcgt cattttgttg gtgcaagcgt agctgaatca
     5641 atcggtaaat tctttgcacc actcttctca gcagcagacg gataccttgg tattaccatt
     5701 atctttggtg cctttgcctt cttctggttt gtgggtattc atggtccatc tattgttgaa
     5761 cctgctatcg cagcgattac ctatgcaaat gctgaagtca acttgaacct tctccaacaa
     5821 ggtatgcatg ctgataaaat ccttacttca ggaactcaaa tgtttatcgt tactatggga
     5881 ggtactggtg cgacactggt tgttccattc atgttcatgt ggttaacaaa atcaaaacgt
     5941 aaccgtgcaa tcggacgtgc ttcagtagtt ccaactttct ttggtgtaaa tgaaccaatc
     6001 ttgtttggtg caccacttgt attaaatcca atcttcttca ttccatttat ctttgctcca
     6061 atcgcaaacg tatggatttt caaattcttt attgaaactc ttggaatgaa ctcattcact
     6121 gctaatctac catggacaac tccagctcca ctaggtctag ttcttggaac taacttccaa
     6181 gtgctatcat tcattcttgc tgcccttcta atcgtggttg acgttgtcat ttactatcca
     6241 ttccttaagg tctatgatga acaaattctt gaagaagaac gttcaggtaa gtctaatgat
     6301 gaattgaaag aaaaagttgc tgcaaacttc aacactgcaa aagcggatgc tattcttgaa
     6361 aaagcgggtg tcgatgcagc acaaaatacc atcactgaag aaacaaatgt cctcgttctc
     6421 tgtgcaggtg gaggaacaag tggtctcctt gcaaatgctt tgaataaggc agcagcagaa
     6481 tacaatgtcc ctgtgaaagc agcagcaggc ggctatggtg ctcaccgtga aatgttacca
     6541 gagtttgatc ttgttatcct tgcccctcaa gttgcttcaa actttgaaga tatgaaagca
     6601 gaaacagata agctcggtat taaactagcg aaaacagaag gcgctcaata catcaaatta
     6661 actcgtgatg gaaaaggtgc tcttgcattc gtacaagcgc aattcgatta aggctagaga
     6721 ctctgaaata gtctcctatc gttacggaaa tcgctatggc gaatttccta ttattaattc
     6781 gtcggtaaaa agatatcgtt tttacctcct catgtcacaa ttcggtgact tggtacaaga
     6841 agtgagatgg agaaggatgg ctcactgact cctctcctct cacttttact ttatttaaat
     6901 caagaaatag gtgaaaaaaa tgacaaaaac acttccaaaa gactttattt ttggtggcgc
     6961 aacagctgct tatcaagcag aaggtgctac acatactgat ggaaaaggac cagttgcttg
     7021 ggataaatat cttgaggata actactggta cactgccgaa ccagctagtg atttttacaa
     7081 tcgatatcca gttgacctca agctagcaga agagtatggt gtcaatggta ttcgaatttc
     7141 tattgcttgg tcacgtattt tcccgactgg ttacggccaa gtaaatgcta aaggtgttga
     7201 gttttatcat aatttatttg cagagtgtca caaacgtcat gttgagcctt ttgtaactct
     7261 tcatcacttt gacacgccag aagctctcca ctcaaatgga gacttcttaa accgtgaaaa
     7321 tatcgaacat tttgtagact acgctgcctt ctgttttgaa gaatttccag aagtaaacta
     7381 ttggacaacc tttaatgaaa ttggaccaat cggtgatggt caatatttag ttggtaaatt
     7441 ccctccagga attcagtacg accttgccaa agtcttccaa tcgcaccaca atatgatggt
     7501 gtctcatgca cgtgctgtaa agctatataa agataaagga tataaagggg aaattggtgt
     7561 tgttcacgcc ctgcctacta aatatcctct agatcatgaa aatccagcag atgttcgtgc
     7621 agctgagttg gaagatatca tccacaataa attcatctta gacgcaactt atctaggtcg
     7681 ctattcagct gaaaccatgg aaggtgtcaa ccatatctta tcagtcaatg gtggtagttt
     7741 ggatcttcgt gaagaagatt ttacagcatt agaagctgca aaagacttga atgatttcct
     7801 aggaatcaac tactatatga gtgactggat ggaagccttt gatggagaaa ctgaaattat
     7861 ccataatggt aaaggtaaaa aaggaagctc taagtatcaa atcaaaggtg ttggtcgtcg
     7921 tgtagctcct gactatgtac cacgcacgga ttgggattgg attatctacc ctcaaggttt
     7981 gtatgaccaa atcatgcgtg tgaagaaaga ttatcctaac tacaagaaaa tttacatcac
     8041 tgaaaatggt ctcggctata aagatgagtt cgtcgataac actgtttacg atgatggtcg
     8101 tattgattac gtgaaacaac acttggagat cttgtctgat gcgattgcag atggagctaa
     8161 tgtaaaaggt tacttcattt ggtcattaat ggatgtcttc tcatggtcaa acggttatga
     8221 gaaacgttat ggtctcttct acgtagattt tgaaactcaa gaacgttatc ctaagaaatc
     8281 agctcactgg tacaagaaag tagcggaaac tcagattata gactagtaga attagtcatt
     8341 agatatagaa ttttagtgag tccaaaagat gttcaaagat gttcaaagat tttatccaat
     8401 ctatttatga aaaagtttat attataaatt tcgaaaaatg ctctcaaata ccgtgtttga
     8461 cgagtgaaga attgaaagtc ttggaaaatg gtatgtctcg actggtaaag aatggatttg
     8521 tcattcagat gatgagctgg aagaatttaa aaatctattt ttaaatttta tcaatcctga
     8581 agaatgggat actatctcct ttgattcaga ttttatgccg tttcaacaat cgtaaccaat
     8641 ttctcaaaaa agttaaatct tatatttagt actctgtaaa actcttatct aatcacgttg
     8701 cttatactca atgaaaatca aagagcaact ttaaactagg aagcgagtcg cagatttctc
     8761 aatgtatagc tttgaggaat tgggcaaaaa gtctttgata tagaaaaaag catagtatca
     8821 ggtgtttcaa cacctgatac tatgcttttt attgtgggaa gatttacttt ttttcttctg
     8881 aaattgagtt gttacccagg ctctttcagt ttattaaggc ttgatgactt taatgtgttt
     8941 agatagctta aaaaggattg aatcacttag tttagaatct gaaacaatag tatcaagatt
     9001 tgatatatta taaaaagtat aaaaatcaaa cttattgaac ttactatgat ctgcgagtaa
     9061 atatttttta ttagaattat ttaaagcgat gcgttgagcc tctccctctt cctcgctaaa
     9121 agtagctaga gctccgtttt gaataccatt acagctaacg aaagctttag aaaattggag
     9181 attagagaga ttttgtaggg tcaatgtgcc aacaaaagca cctgtaatat cgcgataatt
     9241 tccacctatc aaaatcaaat ctgttaattt tcgttcgctt aaaatcagaa aaacaggtag
     9301 actgttggtt acgacgcgga tattgtcaat aggcaactca cgcgcaaaaa actctaatgt
     9361 tgttcctggt ccaatgaaaa tagtttctct ttcttctact agactgcctg caaaatgggc
     9421 tatttcttgt ttttctgccg tttggagggc ttgtttttca atatttgatc gctcattagt
     9481 caaaagggag ttggttcgaa gtttttcagc tccaccatgc acacgaatca gcaaatcttt
     9541 atcagctaat tcctgtaaat agcgccttgc agtcatatct gaaacggcta tttcgtccat
     9601 aatctgttta actgttatgg ttcctttact atttactatc tctaaaattt tggttaattt
     9661 ttcttgtttg agcatattat cacctcgttt cctactacta tcttaccata aacaaactca
     9721 tcattcaaat acaaaaacaa caaaatgaaa caaaaacaaa aatatcgaag tttgttttca
     9781 aaactttcga tatttttgtt gggttataac tttgatgttt ctagtttact ttttgatgat
     9841 tgagagtgat ggagaattag tctaaaccgt agttatagtc atcgtcttgc atggcttcaa
     9901 cttcgccaag aaggtaacca tttccgactt gagagaagaa gtcatggttg gaagttcctg
     9961 ttgaaatacc gttcataacg attgggttga catcttcagc tgaatctggg aaaagtggat
    10021 cttgtcccat gttcatgaga gctttattgg cattgtagcg aaggaaggtt ttaacctctt
    10081 cagtccaacc aacaccgtca taaagactct ctgtgtagcc ttcttcattt tcataaagag
    10141 tatagagtag gtcgtacatc cattctttga gtttttcttg ctcttcttca ggcaattcat
    10201 tgaaaccaag ttggaatttg taaccaatgt aggttccgtg aacagactcg tcacgaataa
    10261 tcaatttaat gatttctgca acgttggcta gtttgttgtt accgagatag tagaggggag
    10321 tgaagaaacc agagtagaag aggaaggttt cgaggaagac gctggcaact ttcttttcaa
    10381 gtgggctgcc gtttaggtag atttcgttga caatctcagc cttcttttgt aggtaaggat
    10441 tggtattggt ccattcgaaa atttcttcaa tctcagcctt agtattcaag gtagaaaaga
    10501 ttgatgagta agatttagcg tggacagatt ccataaattg gatgttattg aaaacagctt
    10561 cctcatgtgg tgtacggatg tctgcgcgaa gggcttgaac cccagtttca gattgcatag
    10621 tgtcaagaag ggttaaacca ccaaaaactt ttccgaccaa gtctttctct ttgttagata
    10681 gctttctcca gtcatccaag tcgtttgata agggaatacg tgtatcgagc caaaattgct
    10741 ccgtcagttt ttcccaagtt gatttgtcga tgacatcttc gatggcattc cagttaatgg
    10801 ctttgtagta agtttccatt taaaatctct ttctgtgttt agtattgcga actcacaatt
    10861 atttctactt taccataatt ctataggagt atcgcacaaa aagtcggaag cccgactttt
    10921 aaaatgttac ataaattatg ttatgacata gtagatttga ttttatctgt gctgcttagg
    10981 gaaaaataat gtttctatgc tagaaactaa atcacacagc tttcacattg gttggcgccg
    11041 acttctccac cgtcatctgt aaaggtacgg acgtagtaga tagacttgat tcccttgtta
    11101 aaggcatagt tacgaaggat ggacaagtca cgtgtcgttt gtttattttc cctcttccat
    11161 tcgtaaaggc cttttggaat gtcactacgc atgaagaggg tgagtgaaag tccttgatcc
    11221 acgtgttcag tcgcagcagc gtaaacatcg atgactttac gcatatccat atcgtaggca
    11281 gaagtgtagt aaggaatggt ttctgtagac aagccagcag cagggtagta gattttacca
    11341 attttcttct cttggcgttc ttcgatacgt tgcgtaatcg ggtggataga agcagaaacg
    11401 tcgttgatat agctgataga accatttggc gctacagcaa ggcgattttg gtggtaaaga
    11461 ccatcttctt gaaccttgtc gcgaagttca gcccaatcag caacaccagg gataaagaca
    11521 tttttgaaga gttctttaac acggtctgat gttggaacaa attcaccagt tacatacttg
    11581 tcaaagtaac ttccgttagc atagtctgat ttttcaaagt tgtggaaggt aataccacgt
    11641 tcacgcgcaa tattgtttga ctctaccaag gtccaatagt tcataagcat aaagtagatg
    11701 cttgtaaatt caacagactc aggtgaacca tattcaatga gttgttgggc aaggtagctg
    11761 tgcagtccca tggcaccgag accaaaggtg tgggcttggc tatttccatg gtcaatcgtt
    11821 ggtacagcta cgatatgtga actatctgta acgaaagtaa gggcacgaac catagcacgg
    11881 atagaacgac caaaatcagg tgaagtcatc atgttaacca cgttggttga acccaggtta
    11941 catgaaacat ctgttcccat ttgaaggaat tcttgagcat cgttgatcaa gcttggttct
    12001 tgaacttgaa gaatctcaga acacaagtta ctcatgataa tctttccatc aacaggattt
    12061 gcacggttag ccgtatctat gttgactaca taaggatagc cagactcttg ttgcaattta
    12121 gagatttcag tttccaaatc ccgcgccttg atttttgtct tgcgaatatt tggatttgcg
    12181 accaattcat cgtatttttc agtaatgtcg atgtaattga atggcacacc gtattctttt
    12241 tctacagagt aagggctgaa gaggtacatt tcttcatttt tacgagccaa ttcgtagaat
    12301 ttatcaggta ctacaacacc aagtgataga gtcttgacac gtactttttc atcagcgttt
    12361 tctttcttag ttgaaaggaa agcgatgata tctgggtgaa agacgttgag gtagacaaca
    12421 ccggcacctt gacgttgccc caattggttg gagtaagaga agctgtcttc aaaaagcttc
    12481 ataacaggaa cgacacctga agcagctcct tcatagcctt tgataggtgc accagcttca
    12541 cgaaggttgc tgagagtaat tcccacacca ccaccaatac gtgaaagttg aagagctgag
    12601 ttgatagaac gtccgataga gttcatatca tccgtcactt ggattaggaa acaagatacc
    12661 aactccccac gacgagcacg tccagcattc aagaaggaag gagtagcagg ttggtagcgt
    12721 tggtggatga tttcattggc aatatcgatt gcaacagctt cattcccatc agcgaaataa
    12781 agggcgttga agaagacacg gtcttccata ttttcaagat agtattcacc gtcattagtc
    12841 tttaaggcat attgattgta aaatttataa gctgccatga atgacttgaa ttggaagttt
    12901 tggtctttga taaattgagc caattcttcc aagaactctg gacggtattt cttgataaag
    12961 gctgtttcga tgtagttgtg ttcaatgagg taattgattt tgtctttgat tgaatcaaaa
    13021 accatagtgt ttggaactac attttcttta aagaaagcat ccaaggcttc cttatcttta
    13081 tgaagcatga tttgtccatt aacaggacgg ttaatttcgt tattaagacg gaagtaagtc
    13141 acgtcttcaa gatgttttaa tcccataaaa tttcccttat ctaattacaa aagaaaggct
    13201 tctaagttag ccctaaaagc agtttcttct ggatgatgta ctaagattat gctaattgtt
    13261 tcagttttcc tggttggaaa cctgaaaaga cttcagttgg tgtttggata acaggagctg
    13321 cgctaaaacc gagctcttta acttgatcga cgtactcagg ttgctcatca agattgattt
    13381 cacgataaga gacattatta ctgtccaaga aacgcttggt cattttacat tggacacaat
    13441 tgtttttaga ataaacggtt accattgtgt aactcctctt caaaatttaa tactatctta
    13501 gtatatcaga aaataaaatt ttgtcaatga tttaaactaa atatagtggt gttcttttgt
    13561 tgtttttata tataaacaca atatatagtg tttgtattgt gaaatagcaa tgattatcct
    13621 ataaattgtt tttgaagaaa ctatatcctg tgttttgtta tctaggatag aagattttca
    13681 gcaagttatc tgaaaggaaa ttgaaggaaa atccagaaaa tgcttgaaaa aaatcctaga
    13741 agatggtata atactaaatt gtaagggtta tcacatataa ctcaaaaaaa gaaagaacaa
    13801 aaggagagtc aaactatggc ttctaaagat ttccacgtag tggcagaaac aggtattcac
    13861 gcacgtccag caacattgtt ggtacaaact gctagcaaat ttgcttcaga tatcactctt
    13921 gagtacaaag gtaaatcagt taaccttaaa tcaattatgg gtgttatgag tcttggtgtt
    13981 ggtcaaggtg ctgacgtaac tatctcagct gaaggtgcag atgcagatga cgctatcgct
    14041 gcaatctcag aaacaatgga aaaagaagga ttggcataag ggaaatgaca gaaatgctta
    14101 aaggaatcgc agcatctgac ggtgttgcag ttgcaaaagc atatctactc gttcagccgg
    14161 atttgtcatt tgagactatt acagtcgaag atacaaacgc agaagaagct cgccttgatg
    14221 ccgctctaca ggcatcacaa gacgagcttt ctgttattcg cgagaaagca gtaggtacgc
    14281 tcggtgaaga agcagctcaa gtttttgatg ctcacttaat ggttcttgct gacccagaaa
    14341 tgatcagcca aatcaaggaa actatccgtg cgaagaaagt gaatgcagaa gcaggtctga
    14401 aagaagttac agatatgttt atcactatct ttgaaggcat ggaagacaac ccatacatgc
    14461 aagaacgcgc agcggatatc cgcgacgtga caaaacgtgt attggcaaac cttcttggta
    14521 aaaaattgcc aaacccagct tctatcaatg aagaagtgat tgtgattgcg catgacttga
    14581 ctccttcaga tacagctcaa ttggacaaaa actttgtaaa agcttttgta accaacattg
    14641 gtggacgtac aagccactca gctatcatgg cacgtacact tgaaattgct gctgtattag
    14701 gtacaaacaa catcactgaa atcgttaaag acggtgacat ccttgctgtt aacgggatca
    14761 ctggagaagt gattatcaac ccaacagatg aacaagcggc agaatttaaa gcagctggtg
    14821 aagcctatgc gaaacaaaaa gctgaatggg cacttttgaa agatgctcaa acagtgactg
    14881 ctgacggtaa acacttcgag ttggctgcca atattggtac tccaaaagac gttgaaggtg
    14941 ttaacaacaa cggtgcagaa gctgttggac tttaccgtac agagttcttg tacatggatt
    15001 ctcaagactt cccaactgaa gatgagcagt atgaagcata caaggctgtt cttgaaggaa
    15061 tgaacggtaa acctgttgtc gttcgtacaa tggatatcgg tggagataag gaacttcctt
    15121 acttcgatat gcctcacgaa atgaacccat tccttggatt ccgtgctctt cgtatctcta
    15181 tctctgagac tggagatgct atgttccgca cacaaatccg tgctcttctt cgtgcgtctg
    15241 ttcacggtca attgcgtatc atgttcccaa tggttgcgct cttgaaagaa ttccgtgcag
    15301 cgaaagcagt ctttgatgaa gaaaaagcaa accttcttgc tgaaggtgtt gcagttgcgg
    15361 ataacattca agttggtatc atgatcgaga ttcctgcagc ggctatgctt gcagaccaat
    15421 ttgctaaaga agttgacttc ttctcaattg gtacaaacga cttgatccaa tatacaatgg
    15481 cagcagaccg tatgaacgaa caagtttcat acctttacca accatacaac ccatcaatcc
    15541 tacgcttgat taacaatgtg atcaaagcag ctcacgctga aggtaaatgg gctggtatgt
    15601 gtggtgagat ggctggtgac caacaagctg ttccacttct tgtcggaatg ggcttggatg
    15661 agttctctat gtcagcaaca tctgtacttc gtacacgcag cttgatgaag aaactcgaca
    15721 cagctaagat ggaagagtac gcaaaccgtg cccttacaga atgctcaaca atggaagaag
    15781 ttcttgaact tcaaaaagaa tacgttaatt ttgattaatc gaaaagtccc tgcaactcag
    15841 ttacagggac tttttttgat attttaaaaa gaattttcaa gaaaatcttt cttataaaaa
    15901 gtccaacctt gaaaaagtag tggtcagaac aaaaaatact taaatggttc ataaaattct
    15961 tgacaagttg gagatttagg agtaaactat taaccagtta agtaatagag aggagtttct
    16021 gcaatttaga aatgaattgc aactagaaat atcaaataga aagagagttt cgatgaaaat
    16081 taataagaaa taccttgttg gttctgcggc agctttgatt ttaagtgttt gttcttacga
    16141 gttgggactg tatcaagcta gaacggttaa ggaaaataat cgtgtttcct atatagatgg
    16201 aaaacaagcg acgcaaaaaa cggagaattt gactcctgat gaggttagca agcgtgaagg
    16261 aatcaatgct gagcaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg
    16321 cgaccactat cattattaca atggtaaggt tccttatgat gcgattttca gtgaagaatt
    16381 actcatgaaa gatccaaact ataagctaaa agatgaggat attgttaatg aggtcaaggg
    16441 tggatatgtt atcaaggtag atggaaaata ctatgtttac cttaaggatg ctgcccacgc
    16501 ggataacgtc cgtacaaaag aggaaatcaa tcgacaaaaa caagaacata gtcaacatcg
    16561 tgaaggtggg actccaagaa acgatggtgc tgttgccttg gcacgttcgc aaggacgcta
    16621 tactacagat gatggttata tctttaatgc ttctgatatc atagaggata ctggtgatgc
    16681 ttatatcgtt cctcatggag atcattacca ttacattcct aagaatgagt tatcagctag
    16741 cgagttggct gctgcagaag ccttcctatc tggtcgggga aatctgtcaa attcaagaac
    16801 ctatcgccga caaaatagcg ataacacttc aagaacaaac tgggtacctt ctgtaagcaa
    16861 tccaggaact acaaatacta acacaagcaa caacagcaac actaacagtc aagcaagtca
    16921 aagtaatgac attgatagtc tcttgaaaca gctctacaaa ctgcctttga gtcaacgaca
    16981 tgtagaatct gatggccttg ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg
    17041 tgttgcagtg ccacacggag atcattacca cttcatccct tactctcaaa tgtctgaatt
    17101 ggaagaacga atcgctcgta ttattcccct tcgttatcgt tcaaaccatt gggtaccaga
    17161 ttcaaggcca gaacaaccaa gtccacaacc gactccggaa cctagtccag gcccgcaacc
    17221 tgcaccaaat cttaaaatag actcaaattc ttctttggtt agtcagctgg tacgaaaagt
    17281 tggggaagga tatgtattcg aagaaaaggg catctctcgt tatgtctttg cgaaagattt
    17341 accatctgaa actgttaaaa atcttgaaag taagttatca aaacaagaga gtgtttcaca
    17401 cactttaact gctaaaaaag aaaatgttgc tcctcgtgac caagaatttt atgataaagc
    17461 atataatctg ttaactgagg ctcataaagc cttgtttgaa aataagggtc gtaattctga
    17521 tttccaagcc ttagacaaat tattagaacg cttgaatgat gaatcgacta ataaagaaaa
    17581 attggtagat gatttattgg cattcctagc accaattacc catccagagc gacttggcaa
    17641 gccaaattct caaattgagt atactgaaga cgaagttcgt attgctcaat tagctgataa
    17701 gtatacaacg tcagatggtt acatttttga tgaacatgat ataatcagtg atgaaggaga
    17761 tgcatatgta acgcctcata tgggccatag tcactggatt ggaaaagata gcctttctga
    17821 taaggaaaaa gttgcagctc aagcctatac taaagaaaaa ggtatcctac ctccatctcc
    17881 agacgcagat gttaaagcaa atccaactgg agatagtgca gcagctattt acaatcgtgt
    17941 gaaaggggaa aaacgaattc cactcgttcg acttccatat atggttgagc atacagttga
    18001 ggttaaaaac ggtaatttga ttattcctca taaggatcat taccataata ttaaatttgc
    18061 ttggtttgat gatcacacat acaaagctcc aaatggctat accttggaag atttgtttgc
    18121 gacgattaag tactacgtag aacaccctga cgaacgtcca cattctaatg atggatgggg
    18181 caatgccagt gagcatgtgt taggcaagaa agaccacagt gaagatccaa ataagaactt
    18241 caaagcggat gaagagccag tagaggaaac acctgctgag ccagaagtcc ctcaagtaga
    18301 gactgaaaaa gtagaagccc aactcaaaga agcagaagtt ttgcttgcga aagtaacgga
    18361 ttctagtctg aaagccaatg caacagaaac tctagctggt ttacgaaata atttgactct
    18421 tcaaattatg gataacaata gtatcatggc agaagcagaa aaattacttg cgttgttaaa
    18481 aggaagtaat ccttcatctg taagtaagga aaaaataaac taatgaaaaa tgaaagtctc
    18541 gataaagagg ctttcatttt tattatgtat atatgtaaaa ttcttgacaa gcaatattaa
    18601 aaagagtaaa ctattaacta gttaattaac cggtttatta ctttatagtg aatcaaatat
    18661 acttaagaaa agaggaaaga atgaaaat
//
LOCUS       DAVMBH010000037        18555 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVMBH010000037 DAVMBH010000000
VERSION     DAVMBH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18555
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.037"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..169)
                     /locus_tag="VYP30_001523"
     CDS             complement(<1..169)
                     /locus_tag="VYP30_001523"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808499.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDGTDVVSSKHCFEVVDGTDVVS
                     SKHCFEVVDGTD"
     gene            402..6833
                     /locus_tag="VYP30_001524"
     CDS             402..6833
                     /locus_tag="VYP30_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1808500.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEATIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEARNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNEGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFADHADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTEVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVEDFVTGGKRTVELDYKYDDKGNITAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDDDRIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            7460..7936
                     /locus_tag="VYP30_001525"
     CDS             7460..7936
                     /locus_tag="VYP30_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1808501.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7974..8279
                     /locus_tag="VYP30_001526"
     CDS             7974..8279
                     /locus_tag="VYP30_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1808502.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8327..9802
                     /locus_tag="VYP30_001527"
     CDS             8327..9802
                     /locus_tag="VYP30_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1808503.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9828..9899
                     /locus_tag="VYP30_001528"
                     /pseudo
     CDS             9828..9899
                     /locus_tag="VYP30_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            10197..16898
                     /locus_tag="VYP30_001529"
     CDS             10197..16898
                     /locus_tag="VYP30_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1808504.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAIRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVHYRADKDIEAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVTAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(17146..18003)
                     /locus_tag="VYP30_001530"
                     /pseudo
     CDS             complement(17146..18003)
                     /locus_tag="VYP30_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722232.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18215..>18555)
                     /locus_tag="VYP30_001531"
     CDS             complement(18215..>18555)
                     /locus_tag="VYP30_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1808505.1"
                     /translation="LASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPVLVFEYYL
                     ITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFLLTLIMYI
                     EMIVELFLMK"
BASE COUNT         6453 a         3128 c         3825 g         5149 t
ORIGIN      
        1 cgtcagttcc atctacaacc tcaaaacagt gttttgagct gactacgtca gttccatcca
       61 caacctcaaa acagtgtttt gagctgacta cgtcagttcc atctacaacc tcaaaacagt
      121 gttttgagca acctgcggct agtttcctag tttgctcttt gattttcatt gagtactaat
      181 cttacttttt aacgtgtgct aaaaaataaa ttaatgcatg ttaatttttc ttgaattaaa
      241 tttttttaaa tgatatactg tttttataga gagataacaa ttatatataa atgtactact
      301 ctatttccta gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt
      361 tattatctat tggaagttaa ataaatatgt aaggaattaa aatgaaaaaa agtacagtat
      421 tgtcattaac cacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag
      481 cagacacatc tagctctgaa gatgctttaa acatctctga taaagaaaaa gtagtattag
      541 ataaggaaac agaaaataaa gagaaacatg aagatattca taatgctata gaaacttcac
      601 aggattttaa agagaagaaa acagcagtca ttgagggaaa agaagttgtt agtaaaaatc
      661 ctgtgacaga caataacact agcaatgaag aagcaacaat caaagaagat tccaatcaat
      721 cccaaggaga tcatacggac tcatttgtga ataaaaacac agaaaatccc aaaaaagaag
      781 ataaacttgt ctatattgct gaatttaaag ataaagaatc tggagaaaaa gcaatcaagc
      841 aactatccaa tcttaagaat acaaaagttt tatatactta tgatagaatt tttaacggta
      901 gtgccataga aacaactcca gataacttgg acaaaattaa acaaatagaa ggtattacat
      961 cggttgaaag ggcacaaaaa gttcaaccca tgatgaatca tgccagaaag gaaattggag
     1021 ttgaggaagc tattgattac ctaaagtcta tcaatgctcc gtttgggaaa aattttgatg
     1081 gtagaggtat ggtcatttca aatatcgata ctggaacaga ttatagacat aaggctatga
     1141 gaatcgatga tgatgccaaa gcctcaatga gatttaaaaa agaagactta aaaggaactg
     1201 ataaaaatta ttggttgagt gataaaatcc ctcatgcgtt caattattat aatggtggca
     1261 aaatcactgt agaaaaatat gatgatggaa gggattattt tgacccacat gggatgcata
     1321 ttgcagggat tcttgctgga aatgatactg aacaagatat caaaaacttt aacggcatag
     1381 atggaattgc acctaatgca caaattttct cttacaaaat gtattctgac gcaggatctg
     1441 ggtttgcggg tgatgaaaca atgtttcatg ctattgaaga ttctatcaaa cacaacgttg
     1501 atgttgtttc ggtatcatct ggttttacag gaacaggtct tgtaggtgag aaatattggc
     1561 aagctattag ggcattaaga aaagcaggca ttccaatggt tgtcgctacg ggtaactatg
     1621 cgacttctgc ttcaagttct tcatgggatt tagtagccaa taatcatctg aaaatgaccg
     1681 acactggaaa tgtaacacga actgcagcac atgaggatgc gatagcggtc gcttctgcta
     1741 aaaatcaaac agttgagttt gataaagtta acataggtgg agaaagtttt aaatacagaa
     1801 atataggggc ctttttcgat aagaataaaa tcacaacaaa tgaagatgga acaaaagctc
     1861 ctagtaaatt aaaatttgta tatataggca aggggcaaga ccaagatttg ataggtttgg
     1921 atcttagggg caaaattgca gtaatggata gaatttatac aaaggattta aaaaatgctt
     1981 ttaaaaaagc tatggataag ggtgcacgcg ccattatggt tgtaaatact gtaaattact
     2041 acaatagaga taattggaca gagcttccag ctatgggata tgaagcggat gaaggtacta
     2101 aaagtcaagt gttttcaatt tcaggagatg atggtgtaaa gctatggaac atgattaatc
     2161 ctaataaaaa aactgaagtc aaaagaaata ataaagaaga ttttaaagat aaattggagc
     2221 aatactatcc aattgatatg gaaagtttta attccaacaa accgaatgta ggtgacgaaa
     2281 aagagattga ctttaagttt gcacctgaca cagacaaaga actctataaa gaagatatca
     2341 tcgttccagc aggatccaca tcttgggggc caagaataga tttactttta aaacccgatg
     2401 tttcagcacc tggtaaaaat attaaatcta cgcttaatgt tattaatggc aaatcaactt
     2461 atggctatat gtcaggaact agtatggcga ctccaatcgt ggcagcttct actgttttga
     2521 ttagaccgaa attaaaggaa atgcttgaaa gacctgtatt gaaaaatctt aagggagatg
     2581 acaaaataga tcttacaagt cttacaaaaa ttgccctaca aaatactgct cgacctatga
     2641 tggatgcaac ttcttggaaa gaaaaaagtc aatactttgc atcacctaga caacagggag
     2701 caggcctaat taatgtggcc aatgctttga gaaatgaagt tgtagcaact ttcaaaaaca
     2761 ctgattctaa aggtttggta aactcatatg gttccatttc tcttaaagaa ataaaaggtg
     2821 ataaaaaata ctttacaatc aagcttcaca atacatcaaa cagacctttg acttttaaag
     2881 tttcagcatc agcgataact acagattctc taactgacag attaaaactt gatgaaacat
     2941 ataaagatga aaaatctcca gatggtaagc aaattgttcc agaaattcac ccagaaaaag
     3001 tcaaaggagc aaatatcaca tttgagcatg atactttcac tataggcgca aattctagct
     3061 ttgatttgaa tgcggttata aatgttggag aggccagaaa caaaaataaa tttgtagaat
     3121 catttattca ttttgagtca gtggaagaaa tggaagctct aaactccaac gggaagaaaa
     3181 taaacttcca accttctttg tcgatgcctc taatgggatt tgctgggaat tggaaccacg
     3241 aaccaatcct tgataaatgg gcttgggaag aagggtcaag atcaaaaaca ctgggaggtt
     3301 atgatgatga tggtaaaccg aaaattccag gaaccttaaa taagggaatt ggtggagaac
     3361 atggtataga taaatttaat ccagcaggag ttatacaaaa tagaaaagat aaaaatacaa
     3421 catccctgga tcaaaatcca gaattatttg ctttcaataa cgaagggatc aacgctccat
     3481 catcaagtgg ttctaagatt gctaacattt atcctttaga ttcaaatgga aatcctcaag
     3541 atgctcaact tgaaagagga ttaacacctt ctccacttgt attaagaagt gcagaagaag
     3601 gattgatttc aatagtaaat acaaataaag agggagaaaa tcaaagagac ttaaaagtca
     3661 tttcgagaga acactttatt agaggaattt taaattctaa aagcaatgat gcaaagggaa
     3721 tcaaatcatc taaactaaaa gtttggggtg acttgaagtg ggatggactc atctataatc
     3781 ctagaggtag agaagaaaat gcaccagaaa gtaaggataa tcaagatcct gctactaaga
     3841 taagaggtca atttgaaccg attgcggaag gtcaatattt ctataaattt aaatatagat
     3901 taactaaaga ttacccatgg caggtttcct atattcctgt aaaaattgat aacaccgccc
     3961 ctaagattgt ttcggttgat ttttcaaatc ctgaaaaaat taagttgatt acaaaggata
     4021 cttatcataa ggtaaaagat cagtataaga atgaaacgct atttgcgaga gatcaaaaag
     4081 aacatcctga aaaatttgac gagattgcga acgaagtttg gtatgctggc gccgctcttg
     4141 ttaatgaaga tggagaggtt gaaaaaaatc ttgaagtaac ttacgcaggt gagggtcaag
     4201 gaagaaatag aaaacttgat aaagacggaa ataccattta tgaaattaaa ggtgcaggag
     4261 atttaagagg aaaaatcatt gaagtcattg cattagatgg ttctagcaat ttcacaaaga
     4321 ttcatagaat taaatttgct gatcatgctg atgaaaaggg gatgatttct tattacctag
     4381 tagatcctga tcaagattca tcaaaatatc aaaagcttgg cgagattgca gaatctaaat
     4441 ttaaaaattt aggaaatgga aaagagggta gtctaaaaaa agatacaact gaggtagaac
     4501 atcatcatca agaaaatgaa gagtctatta aagaaaaatc tagttttact attgatagaa
     4561 atatttcaac aattagagac tttgaaaata aagacttaaa gaaactcatt aaaaagaaat
     4621 ttagagaagt tgaggacttt gtaactggtg gaaaaagaac agtagaactt gattataaat
     4681 atgacgataa aggaaatata actgcctatg acgatggtag tgccttacaa tatgaaactg
     4741 aaaaacttga cgaaataaaa tcaaaaattt atggtgttct aagcccatct aaagatggac
     4801 actttgaaat tcttggaaag ataagcaatg tttctaaaaa tgccaaggta tattatggaa
     4861 atagctataa atcgatagaa atcaaagcga ctaagtatga ctcacattca aaaacgatga
     4921 catttgattt atacgctaat attaatgata ttgtggatgg attagctttt gctggagata
     4981 tgagattatt tgttaaagat gatgatcgaa taaaagctga aactaaaatt agaatgcctg
     5041 aaaaaaataa ggaaactaaa gcagaatatc cctatgtatc aagttatggg aatgtaatcg
     5101 aattaggaga aggagatctt tcaaagaaca aaccagacaa tttaactaaa atggaatctg
     5161 gtaaaatcta ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa
     5221 gaaaaggcta tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag
     5281 gaaatggagt ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa
     5341 gagtcctttc agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta
     5401 cccaagctgt attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta
     5461 catttaaaat gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt
     5521 cttctaaact tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca
     5581 atgtagaagc tataaaagaa gatggctcca tgttatttat tgataccaaa ccagtaaacc
     5641 tttcaatgga taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc
     5701 cagaatttta tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag
     5761 ttaatgaatc ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta
     5821 gagattttaa tattaagttg aatgttaaag acggtgacat catggactgg ggaatgaaag
     5881 actataaagc aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc
     5941 aaactggcta tagcaatttg aatgctaaag cagttggagt ccactatcag tttttatatg
     6001 ataatgttaa acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg
     6061 atggaaaatc tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga
     6121 ttcaagaaca acatatttat ataaatggaa aagaatatac atcatttgat gatattaaac
     6181 aaataacaga caagacacta aacattaaga ttgttgtaaa agattttgca agaaatacaa
     6241 ccgtaaaaga attcatttta aataaagata cgggagaggt aagtgaatta aaacctcata
     6301 gggtgactgt gaccattcaa aatggaaaag aaatgagttc aacgatagtg tcggaagaag
     6361 attttatttt acctgtttat aagggtgaat tagaaaaagg ataccaattt gatggttggg
     6421 aaatttctgg tttcgaaggt aaaaaagacg ctggctatgt tattaatcta tcaaaagata
     6481 cctttataaa acctgtattc aagaaaatag aggagaaaaa ggaggaagaa aataaaccta
     6541 cttttgatgt atcgaaaaag aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa
     6601 gtcacagaaa agaggattta caaagagaag atcattcaca aaaatctgat tcaactaagg
     6661 atgttacagc tacagttctt gataaaaaca atatcagtag taaatcaact actaacaatc
     6721 ctaataagtt gccaaaaact ggaacagcaa gcggagccca gacactatta gctgccggaa
     6781 taatgtttat agtaggaatt tttcttggat tgaagaaaaa aaatcaagat taagataaaa
     6841 gctatagaaa aaaatggttt atgtactgag attagatagt gaggtgatga catagttttg
     6901 tgaaaacagc catttataac tcaattattt agtttacttc actattgata ctatttggag
     6961 ttattaatga acttagttta gataactaat gaattgattg aaagggttag tattgacaat
     7021 attggtcata ttgattagaa aataaagtct atcaaaattt aaaggctaat agaggtgatg
     7081 agacaatttc aaggaattaa gtagcgtttg gttgcttaat tcctttttat ttggaaggaa
     7141 gtttttcgta accgcccaat aacgaagtct attgggcggt tacgatatga tcactgactt
     7201 cgtcagtctt atctacaacc tcaaaacagt gttttgagca acctgcggct agcttcctag
     7261 cttactcttt gattttcatt gagtattaga acagaaaaaa tgcttggagt atttgtttgt
     7321 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
     7381 agaacagaaa gcaattgaca acggtttcat atagtgttat acttatggca taaagttaat
     7441 ggaaagaagg gaaaaactta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
     7501 cttagaagcg gataatcaag aacatctctt tgatcaggtt gcaactttat tggaagaacg
     7561 agaaattgta actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
     7621 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga
     7681 tattgttcat aatctagctg agaaagtggt ggttgttcga ttagaaaaac cagtaacttt
     7741 tcacaatatg atagctcctg ataaggaagt agaagtatcc ctacttttct ttatcattaa
     7801 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
     7861 tggacatctt gaagacctat caaaaatttc cgaaccagaa aaactttatg cttacattgc
     7921 tgaagcaacc gcttaatctt gtctattaaa aaataaaatc ggaggaaatc caaatgatta
     7981 aaattcttgc tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag
     8041 aagaagaact ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg
     8101 taaacgaaga ccttatgaaa ggttacgata tctttacacc aatcgctgca acagaccttg
     8161 gttttgaacc aggtatccca gttatcgaag ctgggccaat cttattccgt atcccagcaa
     8221 tgagcgctcc agtatttgac aatattgaag cagctattaa agaacatgga ttaagctaat
     8281 tctaatttgt taacattcat ataacataaa aaagggagga actgttatgg atgcaatctt
     8341 tgacctaatc ggaaaggttt tcaatcccat cttagaaatg ggtggacctg tcatcatgtt
     8401 gatcattttg acagtattgg ctttactttt tggagtgaaa ttctccaaag cgcttgaagg
     8461 tggtatcaaa cttgccatcg ctcttacagg tatcggtgct atcatcggta tgctaaatgg
     8521 tgctttctca gcatcacttg caaaattcgt tgaaaacact ggtatccaat tgagtattac
     8581 agacgttggt tgggcaccac tcgcaacaat cacttggggt tctgcttgga cactatactt
     8641 cttgctcatc atgttgattg tcaacgtagt gatgcttgct atgaagaaaa ccgatacact
     8701 tgatgtcgat atctttgata tctggcactt gtctatcaca ggtctcttga ttaaatggta
     8761 tgctgataac aatggtgtga gtcaaggggt ttcactcttt attgctacag cagctatcgt
     8821 ccttgtcggt gtgttgaaaa ttatcaactc tgacttgatg aaacctacat ttgatgacct
     8881 tcttaacgct ccaagttcat caccaatgac atcaactcac atgaactaca tgatgaaccc
     8941 agttatcatg gttttggata agatttttga aaaattcttc ccaggccttg ataaatatga
     9001 ctttgatgct gctaaattga acaagaaaat cggtttctgg ggatctaaat tcttcatcgg
     9061 tttcatcctt ggtatcgtta tcggtattat gggaactcca catccaattg caggtgttgc
     9121 agatgcagat aaatggcgtc ttgttatcaa aggatggttg tctcttggtt tgactgccgg
     9181 tgtatctttg gaactcttct cacttatcgg ttcatggttc atcgcagccg tagaaccact
     9241 atcacaaggt attacaaacg ttgctactaa acgtcttcaa ggacgtaaat tcaatatcgg
     9301 tcttgactgg ccattcatcg ctggtcgtgc tgaaatctgg gcttgtgcca acgtacttgc
     9361 accaatcatg ttgattgaag cagtgcttct ttcaaaagtt ggaaatggta tcttgccact
     9421 tgcaggtatc atcgctatgg gtgttactcc agctctcttg gttgtaactc gtggtaaatt
     9481 gctccgtatg attatcttcg gaacactctt gttgccactc ttccttcttt caggtacact
     9541 tattgcacca tttgcaacag aacttgctaa aggtgtaggt gccttcccag aaggtgtgag
     9601 ccaaactcaa ttgattactc actctactct tgaaggacca atcgaaaaac ttcttggttg
     9661 gacaattggt aacactacaa ctggtgatat caaagcaatc cttggtgcag tagtcttcct
     9721 tgtattctat atcggtatct ttgcttggta cagaaaacaa atgatcaaac gtaacgaaga
     9781 gtacgcagca aaagcaaaat aatgcgctcc tataaaatat aaacttaatg aaaatcaaag
     9841 agcaaactag gaagctagcc gcaggttgct caaaacacag ttttgaggtt gtagataaga
     9901 ctgacgaagt cagctcaaaa catggttttg aggttgtaga taagactgac gaagtcagct
     9961 caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg
    10021 aggttgtaga tgaaactgac gaagtcagta atcatatcta cggcaaggcg acactgacga
    10081 agtttgaatt ggattttcgc agagtgtaaa ttgttgaaac taggttgtca taccatgtat
    10141 accacttggg ctttggtagt agctaactgc actaaatata atataaggag ggttttatgg
    10201 ggaaaggcca ttggaatcgg aaaagagttt atagcattcg taagtttgct gtgggagctt
    10261 gctcagtaat gattgggact tgtgcagttc tattaggagg aaatatagct ggagaatctg
    10321 tagtttatgc ggatgaaaca cttattactc atactgctga gaaacctaaa gaggaaaaaa
    10381 tgatagtaga agaaaaggct gataaagctt tggaaactaa aaatgtagtt gaaaggacag
    10441 aacaaagtga acctagttca actgaggcta ttgcatctga gaagaaagaa gatgaagccg
    10501 taactccaaa agaggaaaaa gtgtctgcta aaccggaaga aaaagctcca aggatagaat
    10561 cacaagcttc aagtcaagaa aaaccgctca aggaagatgc taaagctgta acaaatgaag
    10621 aagtgaatca aatgattgaa gacaggaaag tggattttaa tcaaaattgg tactttaaac
    10681 tcaatgcaaa ttctaaggaa gccattaaac ctgatgcaga cgtatctacg tggaaaaaat
    10741 tagatttacc gtatgactgg agtatcttta acgatttcga tcatgaatct cctgcacaaa
    10801 atgaaggtgg acagctcaac ggtggggaag cttggtatcg caagactttc aaactagatg
    10861 aaaaagacct caagaaaaat gttcgcctta cttttgatgg cgtctacatg gattctcaag
    10921 tttatgtcaa tggtcagtta gtggggcatt atccaaatgg ttataaccag ttctcatacg
    10981 atatcaccaa ataccttcac aaagatggtc gtgagaatgt gattgctgtc catgcagtca
    11041 acaaacagcc aagtagccgt tggtattcag gaagtggtat ctatcgtgat gtgactttac
    11101 aagtgacaga taaggtgcat gttgagaaaa atgggacaac tattttaaca ccaaaacttg
    11161 aagaacaaca acatggcaag gttgaaactc atgtgaccag caaaatcgtc aatacggacg
    11221 acaaagacca tgaacttgta gccgaatatc aaatcgttga acgaggtggt catgctgtaa
    11281 caggcttagt tcgtacagcg agtcgtacct taaaagcaca tgaatcaaca agcctagatg
    11341 cgattttaga agttgaaaga ccaaaactct ggaccgtttt aaatgacaaa cctgccttgt
    11401 acgaattgat tacgcgtgtt taccgtgacg gtcaattggt tgatgctaag aaggatttgt
    11461 ttggttaccg ttactatcac tggactccaa atgaaggttt ctctttgaat ggtgaacgta
    11521 ttaaattcca tggagtatcc ttgcaccacg accatggggc gcttggagca gaagaaaact
    11581 ataaagcaga atatcgccgt ctcaaacaaa tgaaggagat gggagttaac tctatccgta
    11641 caacccacaa ccctgctagt gagcaaacct tgcaaatcgc agcagaacta ggtttactcg
    11701 ttcaggaaga ggcctttgat acgtggtatg gtggcaagaa accttatgac tatggacgtt
    11761 tctttgaaaa agatgccact cacccagaag ctcgaaaagg tgaaaaatgg tctgattttg
    11821 acctacgtac catggtcgaa agaggcaaaa acaaccctgc tatcttcatg tggtcaattg
    11881 gtaatgaaat aggtgaagct aatggtgatg cccactcttt agcaactgtt aaacgtttgg
    11941 tcaaggttat caaggatgtt gataagactc gctatgttac catgggagca gataaattcc
    12001 gtttcggcaa tggtagcgga gggcatgaga aaattgctga tgaactcgat gctgttggat
    12061 ttaactattc tgaagataat tacaaagccc ttagagctaa gcatccaaaa tggttgattt
    12121 acggttcaga aacatcatca gcaacccgta cacgaggaag ttactatcgc cctgaacgtg
    12181 aattgaaaca tagcaatgga cctgagcgta attatgaaca gtcagattat ggaaatgatc
    12241 gtgtgggttg ggggaaaaca gcaaccgctt catggacttt tgaccgtgac aacgctggct
    12301 atgctggaca gtttatctgg acaggtacgg actatattgg tgaacctaca ccatggcaca
    12361 accaaaatca aactcctgtt aagagctctt actttggtat cgtagataca gccggcattc
    12421 caaaacatga cttctatctc taccaaagcc aatgggtttc tgttaagaag aaaccgatgg
    12481 tacaccttct tcctcactgg aactgggaaa acaaagaatt agcatccaaa gtagctgact
    12541 cagaaggtaa gattccagtt cgtgcttatt cgaatgcttc tagtgtagaa ttattcttga
    12601 atggaaaatc tcttggtctt aagactttca ataaaaaaca aaccagcgat gggcggactt
    12661 accaagaagg tgcaaatgct aatgaacttt atcttgaatg gaaagttgcc tatcaaccgg
    12721 gtaccttgga agcaattgct cgtgatgaat ctggcaagga aattgctcga gataagatta
    12781 cgactgctgg taagccagcg gcagttcgtc ttattaagga agaccatgcg attgcagcag
    12841 atggaaaaga cttgacttac atctactatg aaattgttga cagccagggg aatgtggttc
    12901 caactgctaa taatctggtt cgcttccaat tgcatggcca aggtcaactg gtcggtgtag
    12961 ataacggaga acaagccagc cgtgaacgct ataaggcgca agcagatggt tcttggattc
    13021 gtaaagcatt taatggtaaa ggtgttgcca ttgtcaaatc aactgaacaa gcagggaaat
    13081 tcaccctgac tgcccactct gatctcttga aatcgaacca agtcactgtc tttactggta
    13141 aaaaagaagg acaagagaag actgttttgg ggacagaagt agcaagagtt cgtacattaa
    13201 ttggtaaaga accaaaaatg ccgaaaacag taggttttgt atacagcgat ggtagtcgtg
    13261 aaaaacttcc agtaacttgg tctcaagtcg atgttagtca agcaggagtt gtgactgtta
    13321 aaggtacagc aaatggacgt gaggtagagg ctcatgtcga ggttctagca attgcgaaag
    13381 aattaccaac agttaaacgt attgctccaa atactgactt gaattctgta gacaaatctg
    13441 tttcttatgt tttgactgat ggaagtgtac aagagtacga agtagatagc tgggagatta
    13501 cggaagtaga taaagccaaa ctttcagtag ctggatcacg tattcaaatg actggtcagt
    13561 tagctggaga aactattcat gcaacccttg tggtagaaga aggaaatgct gcagcacctg
    13621 tagtgccaac tgttactgtt ggaggtgaag cagtaacagg tcttactagt cgacaaccaa
    13681 tgcaatatcg tactctatct tatggtgccc aattgccaga agtcacagca agtgctgaaa
    13741 atgctgatgt gacagttctt caagcaagcg cagcaaacgg catgcgtgca agcatatttg
    13801 ttcagcctaa agatggtggc cctcttcaaa cctatgcaat tcaattccta gaagaagcac
    13861 caaaaattgc tcacttgagc ttgcaagtgg aaaaagctga cagtctcaaa gaagaccaaa
    13921 ctgtcaaatt gtcggttcga gctcactatc aagatggaac gcaagctgta ttaccagctg
    13981 ataaagtaac cttctctaca agtggtgaag gggaagtcgc aattcgtaaa ggaatgcttg
    14041 agttgcataa gccaggagca gtcactctga acgctgaata tgagggagct aaaggccaag
    14101 ttgaactcac tatccaagcc aatactgaga agaagattgc gcaatccatc cgtcctgtaa
    14161 atgtagtgac agatttgcat caggaaccaa gtcttccagc aacagtaaca gttgagtatg
    14221 acaaaggttt ccctaaagct cataaagtca cttggcaagc tattccgaaa gaaaaactag
    14281 actcctatca aacatttgaa gtactaggta aagttgaagg aattgacctt gaagcgcgtg
    14341 caaaagtctc tgtagaaggt atcgtttcag ttgaagaagt cagtgtgaca actccaatcg
    14401 cagaagcacc acaattacca gaaagcgttc ggacatatga ttcaaatggt cacgtttcat
    14461 cagctaaggt tgcatgggat gcgattcgtc cagagcaata cgctaaggaa ggtgtcttta
    14521 cagttaatgg tcgcttagaa ggtacgcaat taacaactaa acttcatgtt cgcgtatctg
    14581 ctcaaactga gcaaggtgca aacatttctg accaatggac cggttcagaa ttgccacttg
    14641 cctttgcttc agattcaaat ccaagcgacc cagtttcaaa tgttaatgac aagctcattt
    14701 cctacaataa ccaaccagcc aatcgttgga caaactggaa tcgtagtaat ccagaagctt
    14761 cagtcggtgt tctgtttgga gattcaggta tcttgagcaa acgctccgtt gataatctaa
    14821 gtgtcggatt ccacgaagac catggagttg gtgcaccgaa gtcttatgtg attgagtatt
    14881 atgttggtaa gactgtccca acagctccta aaaaccctag ttttgttggt aatgaggacc
    14941 atgtctttaa tgattctgcc aactggaaac cagttactaa tctaaaagcc cctgctcaac
    15001 tcaaggctgg agaaatgaac cactttagct ttgataaagt tgaaacctat gctattcgta
    15061 ttcgcatggt taaagcagat aacaagcgtg gaacgtctat cacagaggta caaatctttg
    15121 cgaaacaagt tgcggcagcc aaacaaggac aaacaagaat ccaagttgac ggcaaagact
    15181 tagcaaactt caaccctgat ttgacagact actaccttga gtctgtagat ggaaaagttc
    15241 cggcagtcac agcaagtgtt agcaacaatg gtctcgctac cgtcgttcca agcgttcgtg
    15301 aaggtgagcc agttcgtgtc atcgcgaaag ctgaaaatgg cgacatctta ggagaatacc
    15361 gtctgcactt cactaaggat aagaacttac tttctcataa accagttgct gcggttaaac
    15421 aagctcgctt gctacaagta ggtcaagcac ttgaattgcc gactaaggtt ccagtttact
    15481 tcacaggtaa agacggctac gaaacaaaag acctgacagt tgaatgggaa gaagttccag
    15541 cggaaaatct gacaaaagca ggtcaattta ctgttcgagg ccgtgtcctt ggtagtaacc
    15601 ttgttgctga ggtcactgta cgagtgacag acaaacttgg tgagactctt tcagataacc
    15661 ctaactatga tgaaaacagt aaccaggcct ttgcttcagc aaccaatgat attgacaaaa
    15721 actctcatga ccgcgttgac tatctcaatg acggagatca ttcagaaaat cgtcgttgga
    15781 caaactggtc accaacacca tcttctaatc cagaagtatc agcgggtgtg atcttccgtg
    15841 aaaatggtaa gattgtagaa cggactgttg cacaaggaaa agttcagttc tttgcagata
    15901 gtggtacgga tgcaccatct aaactcgttt tagaacgcta tgtcggtcca gagtttgaag
    15961 tgccaaccta ctattcaaac taccaagcct acgacgcaga ccatccattc aacaatccag
    16021 aaaattggga agctgtgcat tatcgtgcgg ataaagacat tgaagccggt gatgaaatta
    16081 acgttacctt taaagctgtc aaagccaaag ccatgagatg gcgtatggag cgtaaagctg
    16141 acaagagcgg tgttgcgatg attgagatga ccttcctggc accgagtgaa ttgcctcaag
    16201 aaagtacgca atcgaagatt cttgtagatg gaaaagaact tgctgatttc gctgaaaatc
    16261 gtcaagacta tcaaattacc tataaaggtc aacggccaaa agtctcagtt gaagaaaata
    16321 atcaagtagc ttcaactgtg gtagatagtg gagaagatag ccttccagta cttgttcgcc
    16381 tcgtttcaga aagtggaaaa caagtcaagg aataccgtat ccacttgact aaggaaaaac
    16441 cagtttctga gaagacagtt actgctgtac aagaagatct tccaaaactc gaatttgttg
    16501 aaaaagattt ggcctacaag acagttgaga aaaaagattc aacactgtat ctaggtgaaa
    16561 ctcgtgtaga acaagaagga aaaactggta aagaacgtat ctttacagcg attaatcctg
    16621 atggaagtaa ggaagaaaaa ctccgtgaag tggtagaagc tccgacagac cgcatcgtct
    16681 tggttggaac caaaccagta gctcaagaag ctaaaaaacc acaagtgtca gaaaaagcag
    16741 atacaaaacc aattgattca agtgaagcta gtcaaactaa taaagcccag ttaccaaata
    16801 caggcagtgc ggcaagccaa gcagcagtag cagcaggttt agctcttcta ggtttgagtg
    16861 caggattagt agttactaaa ggtaaaaaag aagactagaa attttgatac cttctttatc
    16921 attaaaggcc aaagaaaaac tcttgtccta aatagaagat aaagagtctg ggacaaaata
    16981 gttctcaacc acaaaaaagc tagatatttc caattgtgga actctagctt tttaattttg
    17041 agtcattctc ttattgtata gtggattgaa actagaatag tacagtttta cttctaaaac
    17101 attgttagaa atcgatttga ctgtccttat cgatttgtcc tgttcttatt tcattttact
    17161 atattttagg aggttattgg ccataagtac caatcccatg tcaattctca cttgacgctt
    17221 gcccctcaga ttacatctct tgtaacccaa acaagccttt atctgcccaa agacaggttc
    17281 cacatcaatc ttgcgttgag cgaaaatctg tctaccttgg ggagataaaa gcgcctgaca
    17341 ttctttagct ttcaagtttt gatagcgttc gttcatatac agtccccttt tgaggggctg
    17401 attcaggttc gtcggcgtag taaaccttga tttcctgttg aaagtctgtc tgtgttttct
    17461 ggtgcttgat atggtgaaaa cgatagcacc agccatcagg atgtatgtag ctatcctcct
    17521 tgtcattata gtgccaattc gctaagtttt tagctgactc tttataccct ctcttttgtt
    17581 tcttatcaaa catggcatat ttaatcagaa ggggagtgat ttcttcttga aaatagactt
    17641 gtatctgttc ttgaagtttg gcggagaatt tctctgtcgt tttcttccac acaaaactat
    17701 acttgttggc attggcttca atcttagttc cgtcaataaa caaacaatct aaggtcacta
    17761 actcttccat ttttcaattt ttcgaccaga gaaaatccct tgtgaatagg caaatagaag
    17821 agtagataca agcattttag ggtgataaga cgggcgacca aaggcatgat agaaggcgta
    17881 gaagtgatgt tcctccaagg tattcaccac tttttcaata gtaaagacga gatggtcttg
    17941 tggtaagaag gaactgattt ctagtggtaa agttgtttga tttgtgttat agtgaatatg
    18001 catgggatag cctttctaaa tggtttattg ggcaattcta ttttaccaag actatcgtaa
    18061 ccatgcaaaa aaagcaacgg caaatccgtt gctttttttg gagataagag actattgtcc
    18121 cagactcttt tctttgtata aaattgtata gtgttattgt ctatactatt ttgcagagaa
    18181 agcaaaaatc cctagaaaat gcttagggat tcgactattt cattaagaac aattcaacaa
    18241 tcatttctat atacatgata agggttaata agaatcctgc acgccagaag aatttgatga
    18301 atttaggata gtaaaagctg cgttttttca aaaggaagaa aaagacgaga ataatggcta
    18361 ggattgagag ggctagcccc agtctaggga ggaaattatg ggtaaaggtt ttagctgtaa
    18421 tcaggtaata ttcaaatacc aagaccggaa aagccaaatc cgcaaagttt cgtcctagtt
    18481 tttttaatct aaaaagtttg gttaggataa tgcagacgac taaggtcagt atcaataata
    18541 aaatagatgc taatt
//
LOCUS       DAVMBH010000038        18484 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVMBH010000038 DAVMBH010000000
VERSION     DAVMBH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.038"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(31..276)
                     /locus_tag="VYP30_001532"
     CDS             complement(31..276)
                     /locus_tag="VYP30_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1808506.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(291..1463)
                     /locus_tag="VYP30_001533"
     CDS             complement(291..1463)
                     /locus_tag="VYP30_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1808507.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGANPI"
     gene            complement(1522..2367)
                     /locus_tag="VYP30_001534"
     CDS             complement(1522..2367)
                     /locus_tag="VYP30_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1808508.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            2492..3049
                     /locus_tag="VYP30_001535"
     CDS             2492..3049
                     /locus_tag="VYP30_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1808509.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            3068..3535
                     /locus_tag="VYP30_001536"
     CDS             3068..3535
                     /locus_tag="VYP30_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1808510.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            3624..4253
                     /gene="upp"
                     /locus_tag="VYP30_001537"
     CDS             3624..4253
                     /gene="upp"
                     /locus_tag="VYP30_001537"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1808511.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            4427..5017
                     /gene="clpP"
                     /locus_tag="VYP30_001538"
     CDS             4427..5017
                     /gene="clpP"
                     /locus_tag="VYP30_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1808512.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            5096..5344
                     /locus_tag="VYP30_001539"
     CDS             5096..5344
                     /locus_tag="VYP30_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1808513.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            5445..6605
                     /locus_tag="VYP30_001540"
     CDS             5445..6605
                     /locus_tag="VYP30_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1808514.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            6873..7742
                     /locus_tag="VYP30_001541"
     CDS             6873..7742
                     /locus_tag="VYP30_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1808515.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLVTAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            7746..8702
                     /locus_tag="VYP30_001542"
     CDS             7746..8702
                     /locus_tag="VYP30_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1808516.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGATVSAIVLGILNMLLQDVTS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            8702..9466
                     /locus_tag="VYP30_001543"
     CDS             8702..9466
                     /locus_tag="VYP30_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808517.1"
                     /translation="MTLLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLAGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            9466..10176
                     /locus_tag="VYP30_001544"
     CDS             9466..10176
                     /locus_tag="VYP30_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808518.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            10484..11140
                     /locus_tag="VYP30_001545"
     CDS             10484..11140
                     /locus_tag="VYP30_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1808519.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKIKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            11248..12343
                     /gene="prfB"
                     /locus_tag="VYP30_001546"
     CDS             join(11248..11319,11321..12343)
                     /gene="prfB"
                     /locus_tag="VYP30_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1808520.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            12361..13053
                     /gene="ftsE"
                     /locus_tag="VYP30_001547"
     CDS             12361..13053
                     /gene="ftsE"
                     /locus_tag="VYP30_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1808521.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            13046..13972
                     /locus_tag="VYP30_001548"
     CDS             13046..13972
                     /locus_tag="VYP30_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808522.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            14258..16438
                     /locus_tag="VYP30_001549"
     CDS             14258..16438
                     /locus_tag="VYP30_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1808523.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVTAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            16490..17305
                     /locus_tag="VYP30_001550"
     CDS             16490..17305
                     /locus_tag="VYP30_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1808524.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            17511..>18484
                     /locus_tag="VYP30_001551"
     CDS             17511..>18484
                     /locus_tag="VYP30_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1808525.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTTKTYIDSVNDGTWTFKGYDAASAVVNKANVEFVGKWEFK
                     ANPTNAETYTPQVTEETIKVGQTPDLTDNVTNLPNLPAGTKVVDITPAG"
BASE COUNT         5612 a         3381 c         4018 g         5473 t
ORIGIN      
        1 tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta atagagtatg
       61 aacctgttct cgtatttctt cgagagctaa gttactttca agaataatat ttccactttg
      121 aatataagtt cgaacttgtt gaaaatcagc ttctgtcaag atatctacta gataagacat
      181 tttagggata gcattttttc cattaggagt gactcccctt agcaagataa tatgttccaa
      241 agtagttcct ttcttttttt ggggggattg ttccatttag taatgtatat ttagattgga
      301 tttgctcccg ccacccagcc ggtacagagg gcagaagtga tgttaaagcc acccgtgtgg
      361 gcattgatat ccataacttc gcctgcaaag tggaggccag gtaccagctt actttcaagg
      421 gttttaggat tgatttcctt gagactgact ccacccttgg taacaaagga ctttgcaagg
      481 gacatttttc cagttacagg aattttaagt tctttaatgg actggacaag ttgttctcgt
      541 tccttttcag tcagttgttt gactttttca ggatatcctt gtacaaaaaa ttcggccaag
      601 cgttctggta acaaggtttt taaagcgttt ttcaaggatt tttcccgatt ttcttctaga
      661 aatgtaacca agtccttctc agaaagttga ggcaaaacat cgagtgagag aacctcccca
      721 cctttgacaa agctagacat gcgtagggca gcaggacctg acaaaccaaa gtgggtaaag
      781 agtaaatcat gagtgatgac atgcttacca taacttaggg tcacatcgtc cagagaaatc
      841 ccttgtaagg ctttatgtgg aaaatctgtt aataaaggac tttcagcagc ctcaagatcg
      901 gtgatggtat gcttaaaatg gcgagcaatc tcgtgaccaa aaccagtcga accagtcgaa
      961 ggataagact taccacctgt tgtgacaatg agtttctcac aagtgaaggt ttgatccgct
     1021 gacttaagga caaactggtc atctactttt ttaacagaaa cgatttctat ttgagtagca
     1081 acttgaccac ctagttcggt gattttcttt tccaaagctt cgataatagt ccgagacttg
     1141 tcactggctg gaaagacgcg tccgtggtct tcgaccttaa gtttaacacc attttctgta
     1201 aaaaagttga tgatgtcatg attatcgaac tgggagaaaa cactgtaaag aaagcgtccg
     1261 tttccaggaa ttccagctag caggttgtct aagctaccat tgttggtcac attgcaacgt
     1321 cccccaccag tcccagctaa tttttttcca agtttccgat ttttttcgat gaggagggtt
     1381 ttctgtccat aaaagctact ggaaatcgta gccatcatac cagcaggtcc cccaccgatg
     1441 acaatagtat caaaatgttt catagctcta ttgtaccaca aaaaaacaag agatgatggt
     1501 cacctcttgt caagaatgca attaatcaat ttcatagccc atcagcaaac cgccctcttc
     1561 tgcatagaaa ctgcagagac cagaggttgg tagaatttta atatccgctt gtgggaaggt
     1621 ttcacggatt cgctctgaga gctgttgaca acatttttcg ttattgcgtt gggccatgac
     1681 aatacggcca ccagcatatc cagcttttac taactcatca taggcagctt gaactgattt
     1741 ctttgatccc cttgcttttt gtagcaattc gagagttcca gtttcactag cttttccgac
     1801 catacgaatg ttgagaaggc caactaccgt accgataagc ttactcaaac ggccgttctt
     1861 caccaagtta tcgactttgg ctaggacaaa gagcaactta gttttttctt gataggcggt
     1921 gatagcttca accacttctt caaaagacaa gccttggtca atcaagtcat tcaatttttc
     1981 tacgagtagg tcaacttcac caccagcaga taaactatca atcacatgaa tcttagtgtc
     2041 aggatggtct tccagataaa tattctttgc tagttgagcg ctattgtgac tgccagaaag
     2101 ggtacctgtg atggttacta ggaaaatgtt tttggcacct tcaaatgctc gcaaatagtc
     2161 atctgggctt ggacaagctg attttgaagc ttctgcagtt gcatacatgg tttccatcat
     2221 ttggtcaata tcgagactgg cgtcatcaac aaagacctga tcagctactt gaatggttaa
     2281 ggggacactt acaaaggttg tgttaatagc tggtgttggc agttgacgat aatcacaacc
     2341 agagtcagca ataatcttcc aagtcataga aattctccat ctttgtcagt tatacattga
     2401 caaaggttct gtcttttttt acaattatat catgaaaact cttgaaacaa aagcatcatc
     2461 cgtctgttgt gacaagtaga aagaaaatgt tatgtctgaa cgtagaatct ctgaaaagtc
     2521 tcttgaaaat ctcagaaaat caaaccaaga atccaattta ttaaccagag aagccattga
     2581 aacagccctc ttgcaactct tggaaaaaaa ggagctgacc aagattagta tttctgaatt
     2641 ggtcaaacgt gcaggtgttt cgcgtgcggc cttttatcgc aattatgact ccaaagagga
     2701 aattttagag agcgtcttta aacgaactgt ccacaatatt atggaacagc tgcatcatta
     2761 cgatttaaag acagaccttt atttggtttg ggttcacctt ttccgggagg ccagaaagga
     2821 agctagagta attcaattgg ccttggatta ccatctggaa aaaatctttg tccaagccat
     2881 gcaggaattt ctagaaaaat accatgggaa atcaaaaggt gtcagctctt atcttcattc
     2941 cttctggagc tcagccatcg tctctgtcct tctaaaatgg atcaaggatg gcatgaaggt
     3001 accagctgaa aagattgcag atttaggttt accatttttt aaaaaataga gaaaaaggag
     3061 aaaagagatg actgaaaaaa gactggcctg ggatgagtat tttgcagccc aagccctact
     3121 aattgcgaat cgttccactt gtaaacgtgc taaagtgggc gcgattctgg taaaagataa
     3181 taaggttatt tccactggtt acaatggttc ggtgtcaggg actgagcatt gtattgatca
     3241 cgaatgtttg gtcattgaag gccactgtgt tcgcaccctt cacgctgagg tcaatgctat
     3301 ccttcaaggt gctgagcgtg gtgttcccaa aggctttaca gcctatgtaa cccattttcc
     3361 ttgtctcaac tgtacaaaac aattgcttca ggtcggctgc aagcgcgtgg tttatatcaa
     3421 ccagtaccga atggacgact acgcccaata cctttatcaa gaaaaaggga cagaattgac
     3481 ccatttacca cttgagacag tacagacagc tcttaaagag gctgatctaa tgtaaaaatt
     3541 atcaaaaata aatggcttag aaagattttt aaaccgtttt ttggtataat aagaagaata
     3601 aattgaaaga aggaattcca aaaatgggaa aaattgaagt tattaatcac ccactgattc
     3661 aacacaaatt gtcaatcttg cgtcgtacag atacttctac aaaagctttt cgtgagctag
     3721 tagatgagat tgcaatgttg atggggtatg aagtacttcg tgatcttcca ctagaagatg
     3781 tggaaatcga aacaccaatt acaaaaacag ttcaaaaaca attggcaggt aagaaattgg
     3841 ccatcgtccc aatcttgcgt gcaggtatcg ggatggttga tggtctcttg agcttggttc
     3901 cagctgctaa agttggccac atcggtatgt accgtgatga agaaacactt caaccagttg
     3961 aatacttggt gaaattgcct gaggacattg accaacgtca aatttttgta gtagacccaa
     4021 tgttggcaac aggtggctca gcaatcttgg ctgttgattc tcttaaaaaa cgtggcgcat
     4081 caaatatcaa atttgtctgc cttgtatctg ctccagaggg tgtaaaagcc cttcaagaag
     4141 ctcatccaga tgtagaaatc tttacagcag ccttggatga acgtttgaac gaacacggtt
     4201 atatcgttcc aggtcttgga gatgctggag accgcttgtt cggtacaaaa taagatcgaa
     4261 aagaagaatg acttggaaaa gtatttctag tcacgaaagg aggttgggtt tttgtttctg
     4321 tctaatgaaa gcagagcaaa aatttgacct tttttgacca agatattata atagtcttat
     4381 cttcagtcat ttgaccaaca aaattaaaac tcaaaaggag aaatgaatga ttcctgtagt
     4441 tattgaacaa acaagccgtg gagaacgttc ttacgatatt tactcacgtc ttctcaaaga
     4501 ccgcatcatt atgctgacag gtccggttga agacaatatg gctaactctg ttattgccca
     4561 attgcttttc ttggatgccc aagatagtac gaaagatatt tacctttatg tcaatacacc
     4621 aggtggttct gtttcagctg gtttggcaat cgtagatacc atgaacttta tcaaggcaga
     4681 tgtccaaacc attgttatgg gaatggctgc atctatgggg actgtcatcg catcaagtgg
     4741 ggcaaaaggc aaacgtttca tgcttccaaa tgctgaatac atgattcacc aaccaatggg
     4801 cggtacaggt ggtggtaccc aacaaactga tatggctatc gctgcagaac acttgctcaa
     4861 aactcgtaat accttggaaa aaatcttggc tgaaaattca ggtcagtcaa tggaaaaagt
     4921 ccatgcagat gcagaacgtg ataactggat gagcgcccag gaaacacttg aatatggctt
     4981 tattgatgaa attatggcca acaattcatt gaactaatga tgatagaagg caaactcgac
     5041 tgggtttgct ttttttggta taatagggag agatttctta gaaagaggat ttatcatgtt
     5101 tgaaaaagtc aatcgctctg gcttgattat ctatctttac tataatcgtg atgccaaaaa
     5161 actgcaggat tatggagata ttacctatca ttccaagaaa catcgttact tacaactcta
     5221 tgttccaact caagaagtgg agcaattggt cggacgcttg agcaaggaaa aatttattaa
     5281 aaaagttagg gtttgtcata tccaagagtt ggaaacaccc tttgtgggca atctttatcg
     5341 ataggaaaac gttatcatcg aaaaagttca aggaaaacat tgacaatttt ctgataattc
     5401 ggtatattct taacagacta tttaagaaat aaggagacaa aaagatgaag aaaaaatttg
     5461 ccctatcgtt tgtggcgctt gcaagtgtag cacttcttgc agcctgtgga gaagtgaagt
     5521 ctggagcagt caacactgct ggtaactcag tagaggaaaa gacaattaaa atcgggttta
     5581 actttgaaga atcaggttct ttagctgcat acggaacagc tgaacaaaaa ggtgcccaat
     5641 tggctgttga tgaaatcaat gccgcaggtg gtatcgatgg aaaacaaatc gaagtagtcg
     5701 ataaagataa taagtctgaa acagctgagg ctgcttcagt tacaactaac cttgtaaccc
     5761 aatctaaagt atcagcagtc gtaggacctg cgacatctgg tgcgactgca gctgcggtag
     5821 cgaacgctac aaaagcaggt gttccattga tctcaccaag tgcgactcaa gatggattga
     5881 ctaaaggtca agattacctc tttattggaa ctttccaaga tagcttccaa ggaaaaatta
     5941 tctcaaacta tgtttctgaa aaattaaatg ctaagaaagt tgttctttac actgacaatg
     6001 ccagtgacta tgctaaaggg attgccaaat ctttccgcga gtcatacaag ggtgaaatcg
     6061 ttgcagatga aactttcgta gcaggtgaca cagacttcca agcagccctt acaaaaatga
     6121 aagggaaaga ctttgatgct atcgttgttc ctggttacta taatgaggct ggtaagattg
     6181 taaaccaagc gcgtggtatg ggaattgaca aaccaatcgt tggtggtgat ggattcaacg
     6241 gtgaggagtt tgtacaacaa gcaactgctg aaaaagcatc aaacatctac tttatctcag
     6301 gcttctcaac tactgtagaa gtttcagcta aagctaaagc cttccttgac gcttaccgtg
     6361 ctaagtacaa tgaagagcct tcaacatttg cagccttggc ttatgattca gttcaccttg
     6421 tagcaaacgc agcaaaaggt gctaaaaatt caggtgaaat caagaataac cttgctaaaa
     6481 caaaagattt tgaaggtgta actggtcaaa caagcttcga tgcagaccac aacacagtca
     6541 aaactgctta catgatgacc atgaacaatg gtaaagttga agcagcagaa gttgtaaaac
     6601 cataatagaa aaatgttgaa atagggaatg agcctttgac tcactccctg tttcgatatt
     6661 taatactctt cgaaaatctc ttcaaactgc gtcaacgtcg ccttggatta tatatgtgac
     6721 tgacttcgtc agtcttatct acaacctcaa agcagtgctt tgagcaacct gcggctagtt
     6781 tcctagtttg ctctttgatt ttcattgagt ataagaacct atcaaaaagt gagggaaaac
     6841 cctcggaatt ataaatagaa agagtgaatc ttatgctcca acaactcgta aatggtttga
     6901 ttctaggtag tgtttacgcg ctgttagccc taggatatac catggtttac ggaattatca
     6961 agctcatcaa cttcgcccat ggtgatattt atatgatggg agcctttatc ggttatttct
     7021 tgatcaattc tttccaaatg aatttctttg tagcgcttat tgtagctatg ctagtgacag
     7081 ctattcttgg tgtcgtgatt gagtttcttg cttaccgacc tttgcgccac tctactcgta
     7141 ttgctgtttt gattacggct attggggttt ctttcctatt ggagtatgga atggtctatc
     7201 tggttggtgc caatacccgt gccttccctc aagcgattca aacagttcga tatgatttgg
     7261 gaccaattag cttaacaaat gtgcagttaa tgattttggc catttccttg attttgatga
     7321 ttttgttaca agtcattgtc caaaagacta agatggggaa agccatgcgt gcagtatcag
     7381 tagatagcga cgcggcacaa ttgatgggga tcaatgtaaa ccgtacgatt agctttacct
     7441 tcgctttggg ttctgctctt gcgggtgcgg ctggtgttct gattgctctt tattataact
     7501 ctcttgagcc tttgatgggg gttactccag gtcttaaatc tttcgttgcc gcagtacttg
     7561 gtggtatcgg aattattcct ggtgcggctc ttggtggctt tgtgattggt ctattggaaa
     7621 cctttgcgac agcctttggg atgtcagatt tccgtgatgc cattgtttat ggaatcttgt
     7681 tgttgatctt gattgtccgc ccagctggta tccttggtaa gaatgtgaaa gagaaggtgt
     7741 aaacgatgaa ggaaaattta aaagttaata ttctatggtt actccttttg ttagctggct
     7801 atagcttgat tagtgtactg gtttcagtcg gagtacttaa tctattctat gtacagattt
     7861 tacaacaaat tggaattaat attattttgg ctgttggtct caacttaatc gttggttttt
     7921 caggacaatt ttcacttggt catgctggtt tcatggcgat tggtgcctat gcagcagcta
     7981 ttattggttc taaatcacca acctacggtg ccttctttgg agctatgctt gtaggggctt
     8041 tgctttcagg agcagttgcc ttacttgtcg gcattccaac cttgcgcttg aagggggact
     8101 atcttgcggt agcaactcta ggtgtttctg aaattatccg tatctttatc atcaatggtg
     8161 gaagccttac aaatggtgcg gcaggtatct tagggattcc taactttaca acttggcaaa
     8221 tggtttactt ctttgtcgtg attacaacca ttgcaacctt gaacttcttg cgtagcccaa
     8281 ttggtcgttc aaccctctct gttcgtgaag atgaaatcgc tgctgagtca gttggggtta
     8341 atacgactaa aattaaaatc atcgcttttg tctttggtgc cattactgca agtattgctg
     8401 ggtcacttca ggcaggattt atcgggtctg ttgtaccgaa agattacacc ttcatcaact
     8461 caatcaacgt tttgattatt gttgtatttg gtggactcgg ttccattaca ggtgcgactg
     8521 tttcggctat tgttctggga attttgaata tgcttctcca agatgttact agtgtgcgta
     8581 tgattattta cgctttggcc ttggtattgg taatgatttt cagaccaggt ggactccttg
     8641 gaacatggga actgagccta tcacgtttct ttaaaaaatc taagaaggag gaacaaaact
     8701 aatgacatta cttgaagtaa aacagttaac caaacatttt ggtggtctaa cagctgttgg
     8761 agatgtgact cttgaattga acgaagggga actggttgga ttaatcggtc caaacggagc
     8821 tgggaaaacc acccttttca accttttggc cggtgtttat gaaccaagcg agggaacagt
     8881 aactctagat ggtcaccttt tgaatgggaa atcaccttat aagattgcct ctttgggact
     8941 tggacgtact ttccaaaata tccgtctctt taaagattta acagttttag acaatgtttt
     9001 gattgctttt ggaaaccatc acaaacaaca tgtttttact agtttcttac gcttaccagc
     9061 tttttacaag agtgaaaaag aattaaaggc taaagctttg gaattgttga aaatctttga
     9121 tttagatggt gatgcagaga ctcttgctaa aaatctttcc tacggacaac aacgtcgttt
     9181 ggaaattgtt cgtgcccttg ctacggaacc taaaattctc ttcttagatg aaccagcagc
     9241 aggtatgaac ccacaggaaa cagccgaatt gactgagtta attcgtcgta tcaaagatga
     9301 atttaagatt acaatcatgt tgattgaaca cgatatgaat ctggtcatgg aagtaacaga
     9361 acgtatctac gtacttgaat atggccgttt aattgctcaa ggaactccag acgaaattaa
     9421 gaccaataaa cgcgttatcg aagcttatct aggaggtgaa gcctaatgtc tatgttaaaa
     9481 gttgaaaatc tttctgtgca ttacggtatg atccaagcag tccgtgatgt aagctttgaa
     9541 gttaatgaag gagaagttgt ttcccttatc ggtgccaacg gtgcaggtaa gacaactatt
     9601 cttcgcacct tgtcaggttt ggttcgacca agttcaggaa agattgaatt tttaggtcaa
     9661 gaaatccaaa aaatgccagc tcagaaaatt gtggcaggtg gtctttcaca agttccagaa
     9721 ggacgccacg tctttcctgg cttgactgtt atggaaaatc ttgaaatggg agctttctta
     9781 aagaaaaatc gtgaagaaaa tcaagctaac ttgaagaagg ttttctcacg ctttcctcgt
     9841 cttgaagaac gtaagaacca agatgcagct actctttcag gaggggaaca acaaatgctt
     9901 gccatgggac gcgctcttat gtcaacacca aaacttcttc ttttagatga accatcaatg
     9961 ggacttgccc caatcttcat ccaagagatt tttgatatca ttcaagatat tcagaagcaa
    10021 ggaacaaccg tcctcttgat tgaacaaaat gccaataaag cacttgcaat ctctgaccga
    10081 ggatatgtac tggaaacagg gaaaatcgtc ctatcaggaa caggaaaaga actcgcctca
    10141 tcagaagaag tcagaaaagc atatctaggt ggctaaaaca atccagtgga ttgttttagt
    10201 cggcagatga agattacgaa gtaatcatca atatagtccg ggggaccttt ttagtcggtg
    10261 gatagagatt gcaaacaaat atgcatctac attgaaagct taatttctaa taattgaaaa
    10321 aatcgaatga aaaatttctt accttcattc acagagctct atttcagagc tctttttgct
    10381 agcttattca tacttttttg aatttcgaaa aagaaatgta agcgtttgat agatttacaa
    10441 aaagattgta taatggggat aagaatagaa aaggagaagt ctcatggcag ttaaagattt
    10501 tatgacccgc aaggtagttt atattagtcc agatacaaca gtatctcatg cagcagattt
    10561 gatgagagag caaggtttgc accgtctgcc tgttatcgaa aatgatcaat tagttggttt
    10621 ggtgactgag ggaaccattg cacaagcaag tccatctaaa gcaacaagtc tttctatcta
    10681 tgagatgaat tatcttctga ataagataaa agtaaaagat gtcatgattc gcgatgttgt
    10741 cactgtctca ggctatgcta gtctagaaga tgcaacttat ctgatgttga aaaataagat
    10801 tggtattctc cctgtcgtag ataaccatca agtatacgga gttattactg accgtgatgt
    10861 tttccaagcc tttcttgaaa ttgcaggtta tggcgaagaa gggattcgtg tacgctttgt
    10921 tacagaagat gaagttggtg ttcttggaaa aattgtttct ttgattgtag aagaaaattt
    10981 gaatatctcc catacagtca atattccgcg taaggatggt aaggtgatta tcgaagtgca
    11041 aatcgatgaa tcaattgatt taccagcctt gaaagaaaaa tttgaagcaa atggtattca
    11101 agtggaagaa atcgctcgca cttcagcaaa agtcttgtaa gaagggaagt ccaaaggctt
    11161 cttttttcat gaaaagggga ttagagcaaa agatggaaag aaatgataaa atatgctata
    11221 atgaaataat gtaaaaaagg agtatttatg gacatttcag taattcgtca gaaaattgac
    11281 gcaaatcgtg aaaaattagc ttctttcagg gggtctcttt gacctcgaag ggctagagga
    11341 agagattgcc atcttggaaa acaagatgac agaacctgat ttttggaacg ataatattgc
    11401 ggcccaaaaa acgtcgcaag aattgaatga attaaaaaac acttacaata ccttccataa
    11461 gatggaagag ttgcaggatg aagtcgaaat tttattggat tttttggctg aagacgagtc
    11521 agtgcatgat gaactggtag cgcagttagc cgaacttgat aagataatga ccagctacga
    11581 gatgactcta ctcttgtcag aaccttatga ccacaacaat gccatcttgg aaatccatcc
    11641 aggttctggt ggtactgagg cgcaggactg gggtgatatg ttgcttcgta tgtatactcg
    11701 ttatggtaat gctaaaggct ttaaagtgga agtgttggat taccaagcag gtgatgaggc
    11761 tggtattaag tcggtaactt tatcatttga agggcctaat gcctatggtc tcctcaagtc
    11821 agaaatgggt gttcaccgct tagtgcgaat ctcaccattt gactctgcca aacgtcgcca
    11881 tacctctttc acatctgtag aagtgatgcc agaattggat gatactattg aagtggaaat
    11941 ccgtgaagat gatatcaaga tggatacctt ccgttcaggt ggtgccggtg gacaaaacgt
    12001 caataaggtt tcaacaggtg tacgtttaac ccacattcca actggaattg ttgtccaatc
    12061 aacagtggat cgtacccagt atggaaatag agatcgtgcc atgaagatgt tgcaggctaa
    12121 gctctatcaa atggagcaag agaagaaggc tgcggaggta gattctctca aaggtgagaa
    12181 aaaggagatt acttggggaa gtcaaatccg ttcttatgtc ttcacgcctt atactatggt
    12241 aaaagatcac cgaactagct ttgaggttgc tcaggtagat aaggttatgg atggggacct
    12301 agatggtttt atcgatgctt atctcaagtg gcgaattagc taagatagaa aggaactcac
    12361 atgtcaatta ttgaaatgag agatgtcgtt aaaaaatacg acaacggaac gactgctcta
    12421 cgcggtgttt cggtcagcgt tcaaccgggg gaatttgctt acatcgtagg accttcagga
    12481 gcagggaagt caacttttat tcgttctctg tatcgtgaag taaaaatcga taaaggaagc
    12541 ctatcagttg ctggttttaa tctggttaag atcaaaaaga aagatgtccc gcttctacgt
    12601 cgtagtgttg gggttgtctt tcaggattat aaattgttac caaagaaaac tgtctatgaa
    12661 aatattgctt acgctatgga agtaatcggg gaaaatcgcc gtaatatcaa aaaacgagtg
    12721 atggaagttt tggacttggt tggattgaag cataaggttc gttctttccc aaatgaactc
    12781 tcaggtgggg agcaacagcg gattgcgatt gcgcgtgcaa ttgtaaataa tcccaaagta
    12841 ttgatagctg atgagccaac aggaaatctg gatccggata attcatggga aattatgaat
    12901 ctcttggaac ggattaacct acaaggaaca actattttga tggcgactca taatagccag
    12961 attgtaaata ccttgcgcca ccgtgtcatt gccattgaaa atggccgtgt cgttcgtgac
    13021 gaatcaaaag gagagtatgg atacgatgat tagtagattt tttcgccatt tatttgaagc
    13081 cttaaaaagt ttgaaacgaa atggttggat gacagtagct gctgtcagtt cagtcatgat
    13141 tactttgacc ttggtggcaa tatttgcatc tgttattttc aatacagcga aactagctac
    13201 agatattgaa aataatgtcc gtgtagtagt ttatatccga aaggatgtgg aagataatag
    13261 tcagacaatt gaaaaagaag gtcaaactgt tacaaataat gactaccaca aggtatatga
    13321 ttctttgaag aacatgtcta cggttaaaag tgttaccttt tcaagtaaag aagaacaata
    13381 tgaaaaatta accgagataa tgggagataa ctggaaaatc tttgaaggag atgccaatcc
    13441 tctctatgat gcctatattg tagaggcaaa cactccaaat gatgtaaaaa ctatagccga
    13501 agatgctaaa aaaattgaag gtgtctctga ggttcaagat ggcggtgcca atacagaaag
    13561 actcttcaag ttagcttcat ttatccgtgt ttggggacta gggattgctg ctttgttaat
    13621 ttttatcgca gttttcttga tttcaaatac cattcgtatt accattattt cccgcagtcg
    13681 cgaaattcaa atcatgcgct tggtcggagc taaaaacagt tatatccgtg gaccgttctt
    13741 gttagaagga gcctttatcg gtttattggg agctatcgca ccatctgttt tggtctttat
    13801 tgtttatcaa attgtttacc aatctgtcaa caaatcgttg gtagggcaaa atctatccat
    13861 gattagtcca gatttattta gtccgttgat gattgcccta ctatttgtga ttggggtttt
    13921 cattggttca ttgggatcag gaatatccat gcgccgattc ttgaagattt aggtaaaata
    13981 gctgctttta tgaggagatt gtaaaatctc cttttttgct acaagagttt ttgaaaagag
    14041 atgcgcagaa gaaaagagct tccaaagaag tcccccagag aagacttctt gatggctaat
    14101 ttgaacttga aatttggcgc actagaaatt ttttataaaa aagtgtaatt tttttataaa
    14161 agcctttaca aaaaaaatta aagtggtata attaaatcat agaaagtgca aacgttttcg
    14221 taaaacgttt gcctaaataa aaataaagga gatttgaatg atgaaagata cattcaaaaa
    14281 tgtcttgtct ttcgaatttt ggcaaaaatt cggtaaggct ttgatggtag ttatcgcggt
    14341 tatgccggct gctggtttga tgatttcaat cggtaagtct atcgtgatga ttaacccaac
    14401 ctttgcacca cttgtcatca caggtggaat tcttgagcaa atcggttggg gggttatcgg
    14461 taaccttcac attttgtttg ccctagccat tggaggaagc tgggctaaag aacgtgctgg
    14521 tggtgctttc gccgctggtc ttgccttcat cttgattaac cgtatcactg gtacaatctt
    14581 tggtgtatca ggcgatatgt tgaaaaatcc agatgctatg gtaactactt tctttggtgg
    14641 ttcaatcaaa gttgctgatt actttatcag tgttcttgaa gctccagcct tgaacatggg
    14701 ggtattcgta gggattatct caggttttgt aggggcaact gcttacaaca aatactacaa
    14761 cttccgtaaa cttcctgatg cactttcatt cttcaacggg aaacgtttcg taccatttgt
    14821 agttattctt cgttcagcaa tcgctgcaat tctacttgct gctttctggc cagtagttca
    14881 aacaggtatc aataacttcg gtatctggat tgccaactca caagaaactg ctccaattct
    14941 tgcaccattc ttgtatggta ctttggaacg tttgctcttg ccatttggtc ttcaccacat
    15001 gttgactatc ccaatgaact acacagctct tggtggtact tatgacattt taactggtgc
    15061 agctaaaggt actcaagtat tcggtcaaga cccactatgg cttgcatggg taacagacct
    15121 tgtaaacctt aaaggtactg atgctagtca atatcaacac ttgttagata cagtacatcc
    15181 agctcgtttc aaagttggac aaatgatcgg ttcattcggt atcttgatgg gtgtgattgt
    15241 tgctatctac cgtaatgttg atgctgacaa gaaacataaa tacaaaggta tgatgattgc
    15301 aacagctctt gcaacattct tgacaggggt tactgaacca atcgaataca tgttcatgtt
    15361 catcgcaaca cctatgtatc ttgtttactc acttgttcaa ggtgctgcct tcgctatggc
    15421 tgacgtcgta aacctacgta tgcactcatt cggttcaatc gagttcttga ctcgtacacc
    15481 tattgcaatc agtgctggta ttggtatgga tatcgttaac ttcgtttggg taactgttct
    15541 ctttgctgta atcatgtact ttatcgcaaa cttcatgatt caaaaattca actacgcaac
    15601 tccagggcgc aacggaaact acgaaactgc tgaaggttca gaagaaacca gcagtgaagt
    15661 gaaagttgca gcaggctctc aagctgtaaa cattatcaac cttcttggtg gacgtgtaaa
    15721 catcgttgat gttgacgcat gtatgactcg tcttcgtgta actgttaaag atgcagataa
    15781 agtaggaaat gcagagcaat ggaaagcaga aggagctatg ggtcttgtca tgaaaggaca
    15841 aggggttcaa gctatctacg gtccaaaagc tgacattttg aaatctgata tccaagatat
    15901 ccttgattca ggtgaaatca ttcctgaaac tcttccaagc caaatgactg aagcacaaca
    15961 aaacactgtt cacttcaaag atcttactga ggaagtttac tcagtagcag acggtcaagt
    16021 tgttgctttg gaacaagtaa aggatccagt atttgctcaa aaaatgatgg gtgatggatt
    16081 tgcagtagaa cctgcaaatg gaaacattgt atctccagtt tcaggtactg tatcaagcat
    16141 cttcccaaca aaacatgctt ttggtattgt gacggaagca ggtcttgaag tattggttca
    16201 cattggtttg gacacagtaa gtcttgaagg taaaccattt acagttcatg ttgctgaagg
    16261 acaaaaagtt acagcaggag atctccttgt cacagctgac ttggatgcta tccgtgcagc
    16321 aggacgtgaa acttcaacag tagttgtctt cacaaatggt gatgcaatta aatcagttaa
    16381 attagaaaaa acaggttctc ttgcagctaa aacagcagtt gctaaagtag aattgtaata
    16441 tacttgaggt tggaagctgt attccaacct cttattttgg gagaaaagaa tgaaattttt
    16501 aacactcaat actcacagtt ggatggagaa agaagcagag gaaaaattcc agattttgct
    16561 tgaagatatt cttgaaaagg actatgattt gatttgtttc caagaaatca atcaggagat
    16621 gacctcgtca gaggtggagg ttaatgacct ttatcaagct ttgccagcag ctgagcctat
    16681 tcaccaagac cattatgtta gactcttggt tgaaaagttg ttagagcaag ggaaaaatta
    16741 ctactggacc tgggcttata accatatcgg ctatgaccgc taccatgaag gtgtggctat
    16801 cttgtctaaa acacctattg aagccagaga aattttggtt tcagatgtgg atgatccaac
    16861 agactatcat actcgccgtg ttgccctagc tgaaactgta gtcgatggca aggagctagc
    16921 agttgccagt gttcatctct cttggtggga taaaggtttc caagaagaat gggcacgatt
    16981 tgaggctgtc ttgaaaaaat tgaacaagcc acttttacta gctggagatt ttaacaaccc
    17041 agcaggtcag gaaggttacc aagctatttt agctagtcca ttaggcttac aagacgcatt
    17101 tgaagttgct caagagaaaa gtggtagcta tactgttccg cctgaaattg atggctggaa
    17161 agggaacact gaaccccttc gaatcgatta tgtctttact accaaagagt tagcggtgga
    17221 aaatttacat gtcgtatttg atggtaacaa gagtccacaa gtgagtgatc actatggctt
    17281 gaatgcggta ttaaattgga aataaaatca aaaaatgaaa gggagcgagt cctttcattt
    17341 ttttacaaaa atccctataa ttactatttt ggagaaggag ttttttgtat atttgtatat
    17401 tatgaggaaa tatccacaaa taagttttta aaactttacg gtcaaaaaaa aatcgctaat
    17461 attaactatt tatgatagaa tgaaaattat gaaataaaag gaggactgga atgttttttc
    17521 aggatagaaa gataaaatat tcaatccgca aattgtcagt tgctactgtg tcccttgcga
    17581 ttggattttt gtttgcgcct gcggcgcttg gagtcgctca agtagctcaa gctgatgagc
    17641 tttcaactac tgaacaagtg gagaataaag cagagaatca ggtctcggtg gtctcttttg
    17701 caacagagca agaagaaagt gaaacgactt atgttgatac gacgaataaa gtgacttgga
    17761 catttgcagg atacgataaa gaaaaaattg ttgtaggaaa aggcagacag actttccttg
    17821 gaagctgggt acctactcca aatccagaat atgtattcaa atcatctaaa gcaggtgttc
    17881 cattaccaca aagtattttg ggaatgcttc caaaggatga agcttcttat aaggttggtg
    17941 acaccattgt agccaaacaa cctgctgtag aatcagtagt cgaagaagaa aaagactatg
    18001 tctggacctt caaaggttat gatcagaaga atgcgacgta caatggcaag cgtgtgacat
    18061 ttacaggtat ctgggaagta acgcctagac cgcatcatgt aagctatact tttgtaagtg
    18121 ttacatctgg tgttgatttg cctaaattta tccagaagaa agcaccaaaa gatggctcaa
    18181 cttacttcaa taggacgaga gtttttgcag aagagccgac aacaaagacc tacatagata
    18241 gtgtgaacga tggcacatgg accttcaagg gttatgacgc agctagcgcc gttgttaaca
    18301 aggctaatgt agagtttgta ggtaagtggg aattcaaggc gaatccgaca aatgcggaaa
    18361 cttatacgcc tcaggtaacg gaagaaacta tcaaggttgg acaaacacct gacttgaccg
    18421 ataatgtgac gaacttgcca aaccttccag ctggcactaa ggtagttgat attacacctg
    18481 cagg
//
LOCUS       DAVMBH010000039        18096 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVMBH010000039 DAVMBH010000000
VERSION     DAVMBH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.039"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            276..1322
                     /gene="pheS"
                     /locus_tag="VYP30_001552"
     CDS             276..1322
                     /gene="pheS"
                     /locus_tag="VYP30_001552"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1808526.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1322..1831
                     /locus_tag="VYP30_001553"
     CDS             1322..1831
                     /locus_tag="VYP30_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808527.1"
                     /translation="MIRKVEVADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1908..4313
                     /locus_tag="VYP30_001554"
     CDS             1908..4313
                     /locus_tag="VYP30_001554"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1808528.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVIIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKYDGTAGELTATQKLRRQVRTIAE
                     GVGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTVAVPVDFFYA
                     KGILEALFARLGLQVTYTATSEIASLHPGRTAAISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPAAPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4381..5382)
                     /locus_tag="VYP30_001555"
     CDS             complement(4381..5382)
                     /locus_tag="VYP30_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1808529.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNNWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNTTIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5538..5941
                     /locus_tag="VYP30_001556"
                     /pseudo
     CDS             5538..5941
                     /locus_tag="VYP30_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6067..6333
                     /locus_tag="VYP30_001557"
                     /pseudo
     CDS             6067..6333
                     /locus_tag="VYP30_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6594..8843
                     /gene="metE"
                     /locus_tag="VYP30_001558"
     CDS             6594..8843
                     /gene="metE"
                     /locus_tag="VYP30_001558"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1808530.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVSAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLTVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEVILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8907..9773
                     /gene="metF"
                     /locus_tag="VYP30_001559"
     CDS             8907..9773
                     /gene="metF"
                     /locus_tag="VYP30_001559"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1808531.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10460..12673
                     /gene="pnp"
                     /locus_tag="VYP30_001560"
     CDS             10460..12673
                     /gene="pnp"
                     /locus_tag="VYP30_001560"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1808532.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDAILTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDYKPKKEFTETSKDSE"
     gene            12689..13306
                     /gene="cysE"
                     /locus_tag="VYP30_001561"
     CDS             12689..13306
                     /gene="cysE"
                     /locus_tag="VYP30_001561"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1808533.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13318..14202
                     /locus_tag="VYP30_001562"
     CDS             13318..14202
                     /locus_tag="VYP30_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808534.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSTNT
                     NYLYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14284..15627
                     /locus_tag="VYP30_001563"
     CDS             14284..15627
                     /locus_tag="VYP30_001563"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1808535.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15620..16006
                     /locus_tag="VYP30_001564"
     CDS             15620..16006
                     /locus_tag="VYP30_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1808536.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16010..16894
                     /locus_tag="VYP30_001565"
     CDS             16010..16894
                     /locus_tag="VYP30_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1808537.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17031..17486
                     /locus_tag="VYP30_001566"
     CDS             17031..17486
                     /locus_tag="VYP30_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808538.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTVYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            17483..17629
                     /locus_tag="VYP30_001567"
     CDS             17483..17629
                     /locus_tag="VYP30_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808539.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
     gene            17772..17942
                     /locus_tag="VYP30_001568"
                     /pseudo
     CDS             17772..17942
                     /locus_tag="VYP30_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5445 a         3482 c         4090 g         5079 t
ORIGIN      
        1 taagataggt cttgcaagaa tggtaaaaat ctgataaact aagtagtaat tgaataggaa
       61 tctgaaagac tagtagccca agggaagtat atcagggagg agagccgtga ctgcaagctc
      121 tctatatgaa agctgggtga attcacttgc gcatggattt agaaatgaag gtctgacttg
      181 tcagatgaaa acggatggta ccgcgtgtca acgctccgag tggagttttt ggcatgtggt
      241 tttcttttta tctacgagag actgatggag gaaatatgtc aactattgaa gaacaattaa
      301 aagcgcttcg cgaagaaacg ctgactagct tgaagcagat tactgctgga aatgaaaaag
      361 agatgcaaga tttgcgtgtc tctgtccttg gtaaaaaggg ttcgctcact gaaatcctca
      421 aagggatgaa agatgtttct gctgagatgc gtccaatcat cgggaaacac gtcaatgaag
      481 ctcgtgatgt cttgacagct gcttttgaag aaacagctaa gctcttggaa gaaaagaaag
      541 tcgcggctca actggctagc gagagtatcg atgtgacgct tccaggtcgt ccagttgcga
      601 ctggtcaccg tcacgttttg acacaaacca gtgaagaaat cgaagatatc ttcatcggta
      661 tgggttatca agtcgtggat ggttttgaag tggagcaaga ctactataac tttgaacgta
      721 tgaaccttcc aaaagaccac ccagctcgtg atatgcagga tactttctat atcactgaag
      781 aaatcttgct ccgtacccac acgtctccag ttcaggcgcg tgctatggat gcccatgatt
      841 tttctaaagg tcctttgaag atgatctcgc cagggcgtgt cttccgtcgc gatacggacg
      901 atgcgaccca cagtcaccaa ttccaccaaa tcgaaggctt ggtagttggg aaaaatatct
      961 ctatggctga tcttcaagga acgcttcagt tgattgtcca aaaaatgttt ggtgaagagc
     1021 gtcaaattcg tttgcgtcca tcttactttc cattcacaga gccatctgtt gaggtggatg
     1081 tttcttgctt caaatgtggt ggagaaggct gtaacgtatg taagaaaaca ggttggatcg
     1141 aaattatggg ggccggtatg gttcacccac gtgtccttga aatgagtggt atcgatgcga
     1201 ctgtatactc tggctttgcc tttggtcttg gacaagagcg tgtagctatg ctccgttatg
     1261 gaatcaacga tatccgtgga ttctaccaag gagatgtccg cttctcagaa cagtttaaat
     1321 aatgattaga aaagtagaag tggcagatgt tgaggtgttg gctaaaattg ccaaacaaac
     1381 ctttcgtgaa acctttgcgt atgataatac ggaagagcag ttacaggaat actttgaaga
     1441 ggcttatagt ctaaaaactt tgtcaactga gttgggaaat cctgactctg aaacctattt
     1501 cattatgcat gaggaggaga tagctggttt tctcaaagtc aactggggaa gtgctcaaac
     1561 tgagagagaa ttagaggacg cttttgaaat tcaacgcctc tatgtgctac aaaaattcca
     1621 aggatttgga ctaggtaagc aactgtttga attcgcactt gaacttgcta caaaaaatag
     1681 tttttcttgg gcttggttag gtgtttggga gcataataca aaagctcaag cgttttataa
     1741 tcgatatggt tttgaaaaat ttagccaaca tcattttatg gttggtcaaa aagtagatac
     1801 ggattggtta ctgagaaaga aattaaggta agaagaggat tcttctattg aaatgatagg
     1861 aaaggaaaag aactagagtg acaactgtca ttctggagaa ctaaattatg cttgtatctt
     1921 ataaatggtt aaaagaattg gtggacattg atgtgccatc acaagagttg gctgaaaaaa
     1981 tgtcaactac aggaatcgag gtagagggtg tcgaatcacc agctgctggt ctctcaaaaa
     2041 ttgtcgtcgg tgaggtcttg tcttgcgaag atgtgccaga gactcacctc catgtttgtc
     2101 aggttaacgt tggcgaagaa gaagagcgtc agatcgtttg tggtgcccca aatgtgcgtg
     2161 ctgggatcaa ggtcatggtg gctcttccag gagctcgtat cgctgataac tacaaaatca
     2221 aaaaaggaaa aatccgtggt ttggagtcac ttggaatgat ctgttcactt ggtgaattgg
     2281 ggatttctga ctcagttgtg cctaaggaat tcgcagatgg catccaaatc ttgcctgaag
     2341 atgccgtgcc aggtgaggaa gtcttttctt acctagactt ggatgatgaa atcatcgaac
     2401 tttccatcac accaaaccgt gcagatgccc tttctatgtg tggagtggct cacgaagtgg
     2461 cagccatcta tgacaaggca gtcaacttta aagaatttac tctaacagaa actaatgaag
     2521 ctgcggcaga tgccctttct gtcatcattg ggacagacaa ggcgccttac tatgcagctc
     2581 gtatcttgga caatgtgact atcgcaccaa gtccacaatg gttgcaaaac cttctcatga
     2641 acgaaggaat ccgtcccatc aataacgtag tggacgtgac caactacatc ctgctctatt
     2701 ttggtcaacc aatgcatgcc tttgacttgg ataactttga agggactgac atccgtgtgc
     2761 gtgaagcgcg tgctggtgaa aaattggtga ccttggacgg tgaagaacgt gacttggacg
     2821 tgaatgacct agtcatcact gtcgcagaca agccagtagc ccttgcaggt gtcatgggtg
     2881 gtcaagcaac agaaatctct gaaaaatcta gtcgtgttgt ccttgaagct gctgttttca
     2941 atggcaaatc tatccgtaag acaagtggtc gcctgaacct tcgttctgag tcatcttctc
     3001 gctttgaaaa aggaattaat gtggcaacag ttaatgaagc ccttgatgcg gcagctagcc
     3061 tgattgcgga acttgcaggt gcgacggtgc gtaagggcat cgtttcagcg ggtgagcttg
     3121 atacttcaga tgtagaagtt tcttcaaccc ttgctgatgt taaccgtgtc ctcggaactg
     3181 agctgtctta tgctgatgta gaagacgtct tccgtcgtct tggctttggt ctttctggaa
     3241 atgcagacag ctttacagtc agagtcccac gtcgtcgttg ggatatcaca atcgaagctg
     3301 acctctttga agaaattgct cgtatctatg gttatgaccg cttgccaact agtctaccaa
     3361 aatacgatgg tacagcaggt gaattgacag ccacacaaaa actccgccgt caagttcgta
     3421 ctattgctga aggagtaggt ttgacagaaa tcatcaccta tactctaaca actcctgaaa
     3481 aagcagttga gtttacggct caaccaagta accttactga acttatgtgg ccaatgactg
     3541 tggatcgttc agtcctccgt caaaatatga tttcaggtat ccttgatacc gttgcctaca
     3601 acgtggctcg taagaataaa aacttggccc tttacgagat tggaaaagtc tttgaacaaa
     3661 caggtaatcc aagagaagaa cttccaaatg aaatcaacag ttttgccttt gccttgacag
     3721 gcttggttgc tgaaaaagat ttccaaacag tagcagttcc agttgatttc ttctatgcta
     3781 agggaatcct tgaagcgcta tttgctcgtt tgggactcca agtaacctat acagcaacat
     3841 ctgaaatcgc tagccttcat ccaggtcgta cagccgcgat ttcactcggt gaccaagttc
     3901 ttggtttcct tggccaagtg catccagtca ctgctaaggc ttatgatatt ccagaaacgt
     3961 atgtagctga gcttaacctt tcagctatcg aagctgcgct tcagccagcg gctccatttg
     4021 tggaaatcac gaaattccca gcagtcagcc gtgacgttgc ccttctcctc aaggcagaag
     4081 tgactcacca agaagttgta gatgctatcc aagctgccgg cgtgaaacgt ttgacagata
     4141 tcaaactctt tgacgtcttc tcaggtgaaa aactgggact tggtatgaag tcaatggctt
     4201 atagcttgac cttccaaaat ccagaagaca gcttaacgga cgaagaagtc gcacgctaca
     4261 tggaaaaaat ccaagcgtct ctcgaagaaa aagtcaatgc agaagtgcgt taaacgatag
     4321 taggatacaa attccccctc tagtttatga acactagagg ggtgatttta tataaaataa
     4381 ttaaaatgtg atttctgtaa aaatacatct atgatcagag ttttgaaaac ttacaatgtc
     4441 taaatcttta acatagtagt ggtttttagg caataaaata tgatctattg ttgtattaaa
     4501 aagttttgga ctttggctat tccaagttcc tctttcaaaa ggtggcagta catttaatgc
     4561 gtccctatga gagcttattt ttgcaagtgc tccatgacgc atagttgcat taaaatcacc
     4621 tgcaataata gcctttggat attttgaagc caattgatta tgaatgatgt ttaagtcttg
     4681 cttccagatt tccattaaac ctggcagagg aggagcagta tgcaaggcaa tgatatctgg
     4741 tatattttgt tttctcgaat gtaatacaat tgtcccgaac cgtgttgtat gaaaagtttt
     4801 agcttctgta tagaaaccat aacttttctt gacaatcaca gtcacaggag ctattccact
     4861 attggtaggt ggagaagtga aaatatcata gttggccata gaaagtccaa cttgatgaaa
     4921 caatagtttg attctctggt tttcttgctc acctctgata ttggtagcta gttcagggaa
     4981 tatagccata tcggcgtcaa aatggctaaa aattcgctca atatgttgtg cttctatttg
     5041 attagcgacg ttccaagtta ctaattttaa ggttttagtc ttatttgatg cagaagaaag
     5101 ggttttatct gttccgaata atagtaatat gagcgatagt aagagcaaaa tgccagagta
     5161 aaaccgtatt tgtttatttt tcttgtaaaa agatagggaa aaaaatacga aacttaaaat
     5221 agaagccata gttgcagtag ctaaggggaa ggcataaatc tgtgccaaga taggtctggt
     5281 agatagccaa ttattaagat tagaagatgg aaaaaaagaa taagctatga tagggataac
     5341 aaagagaatg accgaaaggg cagagagaaa tgttttaatc attgtgtgag tacctcaatt
     5401 tgcaatggtt gctcggagct aatgtgactt tgtgacttta cttgattgat attcttttta
     5461 ttgtcttcct tatagattaa gtacaaccca agtaaaaaaa gtccaattta agattgaaat
     5521 gattaaaagg cacagaaatg caagacaatt atactacaaa aggcaaacat ttgacaatcg
     5581 atagccgtcg cttaatcgaa cgatggaaaa aagaaggaaa atcaaataga gaaattgcct
     5641 ctctacttgg aaaagctcct caaactatcc acactgaaat aaagcgtggg acagtccgac
     5701 aatgtcttgg aaaagggcgc ttcaaagagg tttattctgc cgactacgct caacagtctt
     5761 aagaaactaa aggaaaagat tctccactat acataaccaa aaattttcgc ctgaaatgat
     5821 ggttatggtt aaaggggtta acgtgggaat ttcaaccatt tactattgga ttcatcgtgg
     5881 aaaattgggg ttaagcaagc aggatctgct ttatcctaga aaaggaaaat cgcttaagaa
     5941 ataggctagc accaacttta aacccactgg tcaatctatc gaatcataat tcgctcattt
     6001 ttttaaaaat acatagacgt aaaaaaaaga gggttaagtg atgaagaata gtgctattgg
     6061 gagtaattgg aaggatgtcc atctgagctc tttagcaagg aggaaatcct tgaaagtgat
     6121 atgcgagtgg ctatcatgag cgagttgatt gaggctaggt atgaacaagg aatcagtcag
     6181 aaaaagctgg aagaagtcag tggaataagc cagcctgtca tagctaggat ggagacagga
     6241 aagactagtc cttagttgga tacagtctta aaagtcctag ccagtttagg aaagacacta
     6301 gcagtcgtcc cacttgaaca gggaaaaagt tgactagaat cagttatagt cttttctaat
     6361 aacaggtcat agtcacttat aagaattact aataacatgt tttagtattc taattggaat
     6421 atagctgtaa agtaagaatt acaaaggatt tgagacgttt gcttcaagtc tttttctttt
     6481 gtccgaaaca gatatatagt ttcaaactat atcaaaccct aattttttac aattatacag
     6541 acgctttctt ttctgttaag atagtttcaa caacaaattt tggaggacac atcatgtcaa
     6601 ctacaatcat cggtttccct cgtttgggcg aattccgtga attaaaattt acaactgaaa
     6661 aatactttag aaaagaaatc tcagaagaag aacttttagc agcagcaaaa gacttgcgtg
     6721 ctaaacactg gaacattgtc aaagaaaaag gcatcactga aattccatca aatgactttt
     6781 ctcactatga taacttccta gatgcggctt tccttttcaa cgtggtgcct gcatccgttc
     6841 aaaacttgga cttgtctgac cttgagcgct acttcgcttt gggacgtggt taccagggag
     6901 aaaaagggga cgttcgcgcc cttccaatga agaaatggtt caacactaac taccactaca
     6961 tcgttcctaa atttgaaaaa gacactcaag taaaattggc tggtcacaag attttcgatg
     7021 agttccaaga agccaaagaa cttggattga acactcgtcc tgttcttgta ggtcccttca
     7081 ctttccttca attgtcagac tttgaagaag gcgtgaaagc agacgacttc gtagatagct
     7141 tagtgtctgc ttaccaagaa gtttttgcta aattggctga acttggtgcg actcgcatcc
     7201 aattggatga agcggctctt gtaaaagact tgacagctga agaaaaagct cttttcttga
     7261 acctttacaa caaactcttg gctgacaaaa aaggtcttga agtcttgctt caaacttatt
     7321 tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt accagtagat gctatcggtc
     7381 ttgactttgt tgaaggtaag aaaactcttg aactcgttaa aggtggcttc ccagctgaca
     7441 agactctcta tgtaggtatt gtcaatggta aaaacatctg gcgcaacaac tacgaaaaga
     7501 gcttgactgt tcttgagcaa atcccagctg aaaacatcgt tttgacaagc tcttgctcac
     7561 ttcttcatgt gccatttaca actgctaatg aagaatttga accagcactc ttgaaccact
     7621 ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt ggatgctatc cgaaatggtc
     7681 aaggttcaga agctcttgca gccaacaaag aactctttgc gactgagcgt gttggtgaaa
     7741 atgctgaact tcgtgcgcgt atcgctggct tgacagacgc agactacact cgtttgccag
     7801 cctttgcaga acgtgaagct atccaagaag aagctttcaa acttccagct cttccaacaa
     7861 caacgattgg ttcattccct caaacaaaag aagttcgtgc caaacgtttg gcttaccgta
     7921 aaggtgaatt gtctcaaaaa gagtacgacg ctttccttgc tgaaacgatt gacgaatgga
     7981 tcaagtggca agaagatatt gactttgatg tccttgttca cggtgaattt gagcgtaatg
     8041 acatggttga gtacttcggt caaaacttgt caggatacct cttctctaaa aatggatggg
     8101 tacaatcata cggtatgcgt ggggtaaaac caccaatcat ctggggtgat gtcactcgtc
     8161 ttaaccctat cactgttaaa tggtctagct atgcacaaag tcgtacaaac aaacctgtta
     8221 aaggtatgtt gactggacct gttaccatcc ttaactggtc attcccacgt gaagacatct
     8281 ctatcaagga ttcaactctc caaatcgccc ttgctatcaa ggatgaagta cttgaccttg
     8341 aagctgctgg tgtgaaaatc atccaaatcg acgaggctgc tcttcgtgaa aaattgccac
     8401 tccgccgtag cgactggtac gaagactacc ttgactgggc tattcctgcc ttccgcttgg
     8461 tacactcaac agtagcgcca gacacacaaa tccacactca catgtgttac tcagaattta
     8521 cagatatcat cccagctatc gataacatgg atgcagacgt tatttccttt gaagctagcc
     8581 gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa cttccaaaca gaagtgggac
     8641 ctggggttta cgatatccac tcacctcgtg taccaaatga aggcgaaatc gacaacacaa
     8701 tcgaagtcat ccttgctaaa gtgccaagca agaaagtttg gatcaaccct gactgtggtt
     8761 tgaaaacacg tggtatccca gaaacaaaag aaagcttgat ccgccttgtt gaagcagcta
     8821 aagctgcgcg tgagaaattg taagattgga tttctctcca tacagtggtt gttcaaaaag
     8881 aaatcaacta gaaaaggtta ttacatatgt cacgccaaac accgtcactc tcatttgaag
     8941 tgttccctcc aaacccagcc gtgggtaatg ataacattat ttcagccttg caggatatgc
     9001 aggagttggc tccccatttt atcagtgtaa ctgccagcaa taataaattt aatatcaagg
     9061 aaacgacggt tcgtttggct gactttatcc aaaatgattt ggcgattccg accattgccc
     9121 acttgccagc tatttatcta actaaggaca aggttgctga aactattgct gacttggaca
     9181 aagttggggt gcagaaaatc ttggctcttc gtggggatat tattccagac gtggaaccac
     9241 aaaaggattt ccgctatgca acagacttga ttgagtttat caaggaacaa acccctcact
     9301 ttgatattat tggagcttgc tatccagaag ggcatccaga ttcgccaaat cagatttcag
     9361 atattcaaaa tcttaagaag aaagtggatg caggctgttc gagcctcgta actcagctct
     9421 tctttgacaa tgagcgcttc tatgactttc aggacaagtg catcttggct gggattgatg
     9481 ttcccattca tgcaggaatt atgccaattc tgaatcgaaa tcaggctctc cgactcttga
     9541 agacttgtga gaatatccat cttccacgca aatttaaagc catcttagac aagtatgagc
     9601 atgaccctga gtcgctcaga gcagcaggac ttgcctatgc agtggaccaa atcgtggact
     9661 tggtaactca ggatgttgcc ggtgtgcatc tctatacgat gaataatgct gatacagcaa
     9721 aatacatcca tcaagcaacc catgccttgt ttaatcacca gtctctagga taataaaagc
     9781 aaaccattct tctcaggtga ggggaatggt tcctttttaa tggtaaagac ctcacttttt
     9841 aagaaaaata tgataaaata aattctgtac gtacttgata caaagatgaa ggtattaaat
     9901 aatacaatgc atttaaactg taagatttaa cgacacgagt gagtcaaatc gatgttattt
     9961 gacgagagag ttagtaaagc atttaactaa tcgcccgata gcgattagcg tgaaagcttt
    10021 agatacttta gtattaaacc tttctaatga tttatatctt gaaaactgaa ctcgcctaca
    10081 actctgtgga aaaagataaa tctccctagg agcagtcgct ccgtcgttcg atttcctatt
    10141 ttcctttgag ttgcttgacg gcttagtatc ttgatgactt gaattttggt ctcatttctt
    10201 aggaaaaaag ataagcttcc tagcactcgt cgagtgcgac gtcaccttcc tatttttcta
    10261 cagaaatgtt cggcaagccg aaccgtccaa aatatcttgt gtaattgaac acggccgaaa
    10321 agctgtgtaa aaaagataaa ctgtcttgtc ttcatcgaag acttcgtcag tttcctattt
    10381 ttactttgct tttgacgtcc ttggtatctt gatctttgta ggcaaggcgt ataatttcat
    10441 caatccaaag gggattaaaa tggcaaaaca agtgtttcaa acgacttttg cgggtcgtga
    10501 gttaattgta gaaactggtc aggttgctaa gcaagcaaat ggctctgttg tcgtacgtta
    10561 cggtgagtca actgtcttga ctgctgccgt tatgtctaag aaaatggcaa ctggggattt
    10621 cttcccactc caagtcaact acgaagaaaa aatgtatgcg gctgggaagt ttcctggtgg
    10681 ctttatgaaa cgtgaaggac gtccttcaac agatgcgatc ttgacagcgc gtttgattga
    10741 ccgtccgatt cgtcctatgt ttgcggaagg tttccgtaat gaagtccaag tcatcaatac
    10801 agtgctttct tatgatgaaa atgcatctgc accaatggct gctatgtttg gttcatcttt
    10861 ggcactgtct atttcagata ttccatttga cggaccaatt gctggggtac aagtgggata
    10921 tgtagatggc caaatcatca tcaacccaag tcaagaacaa gcagagcaat ctcttcttga
    10981 attgacagta gctggaacca agcacgctat caacatggta gagtctggtg ccaaagaatt
    11041 gtcagaagaa atcatgttgg aagcgcttct taaagggcac gaagctgtca aagaattgat
    11101 tgccttccaa gaagaaatcg ttgctgctgt cggtaaagaa aaagcagaag tggaattgct
    11161 tcacgtggat gctgaattgc aagctgaaat cattgcagcc tacaacagtg acctccaaaa
    11221 ggcagttcaa gtagaagaga aattggcccg tgaagctgca actcaagcag tgaaagacca
    11281 agtgactgcc gtttacgaag aaaaatatgc gaaccacgaa gaatttgacc gtattatgcg
    11341 tgatgtggct gaaatcttgg aacaaatgga acacgcagaa gtgcgacgtt taattacaga
    11401 agacaaggtg cgtcctgatg gtcgtaaggt cgatgaaatc cgtcctttgg atgcggttgt
    11461 tgacttcctt cctcgtgtac atggttcagg tctctttact cgtgggcaaa ctcaagctct
    11521 ttcagtcttg accttggctc cgatgggaga aactcaaatc attgatggtt tggatccaga
    11581 gtacaagaaa cgctttatgc accactataa cttccctcaa tattctgtag gggaaacagg
    11641 tcgttacggt gcgccaggtc gtcgtgaaat cggtcacggt gcccttggtg agcgtgctct
    11701 tgctcaagtc ttgccaagct tggaagaatt cccatacgct atccgtctag tagcagaagt
    11761 tttggaatca aacggttctt catctcaagc ttctatctgt gcgggaactc ttgcccttat
    11821 ggctggtggt gtgccaatca aggcgccagt agctggtatt gctatgggac ttatctcaga
    11881 tggaaataac tacacagtat tgacagatat ccaaggtttg gaagatcact ttggagatat
    11941 ggacttcaag gttgcaggta ctcgtgatgg gattacagcc cttcaaatgg atatcaagat
    12001 tcaagggatt actgcagaaa tcttgacgga ggctcttgct caagccaaga aagcgcgttt
    12061 tgaaatcctt gatgtcattg aagcaaccat tccagaagtt cgtccagaat tggctccaac
    12121 tgctccgaaa attgatacga tcaagattga tgtggacaag attaagattg tcatcggtaa
    12181 gggtggagaa accatcgaca agattatcgc tgaaacaggt gttaagattg atatagacga
    12241 agaaggaaat gtgtctatct actctagtga ccaagatgct attaaccgtg ccaaagaaat
    12301 tattgctggt ttggttcgtg aagccaaagt ggatgaagtt taccgtgcta aagtcgttcg
    12361 tatcgagaaa tttggtgcct ttgttaacct ctttgataag acagatgccc ttgttcatat
    12421 ctctgagatg gcttggactc gtaccaatcg tgtagaggat ttggtagaaa tcggggatga
    12481 agttgatgtt aaggttatca aaattgatga aaaaggccgt atcgatgcct ctatgaaggc
    12541 tcttctacct cgtccgccaa aacctgagca tgatgaaaaa ggtgaaaagt ctgagcgccc
    12601 tcaccgccca cgtcatcaaa aggattacaa acctaagaaa gaatttacag aaacatcaaa
    12661 agattcagaa taagaaaagg agaaatgtat ggggtggtgg cgcgaaacca ttgatattgt
    12721 aaaagaaaat gatccagcgg cccgcaccac tttggaggtt ttgctgactt atccaggtgt
    12781 caaggccttg gcggcccacc gtctctcgca ttttctctgg aagcacggct tcaaactatt
    12841 agctcgtatg tacagtcagt tttggcgctt ttggactcag attgagattc atccaggagc
    12901 ccagattgat tcaggtgttt ttattgacca tggttctggt ctggtgattg gagagacagc
    12961 gattgttgaa aaaggcgttc ttctctatca cggagtgact ctcgggggaa cagggaaaga
    13021 ctgtggcaaa cgccatccga ctgtacgaaa gggagccctc atatcagccc atgcccaagt
    13081 tatcgggcct gtggaaattg gtgaaaatgc caaggtcggt gctgcagcag ttgtcgtagc
    13141 agatgtacct agtgacgtga cggttgtcgg tattccggcc aagattgtcc gtcttcatgg
    13201 taagaaagat gagcctgtca ttcacgaagt cgaagaaaaa cgagagtatt atgtcaataa
    13261 actcgagcag gctaaagatg ccagtcacag atcgtctggt ttgtagagga tacctatatg
    13321 attcaagcaa gaaacaagtt aagccaagag gagctatctg aggcgaaaaa agtaattaac
    13381 tgttgccaaa actatgacgg tacctatcgc gatccctatc tctctaacat gcttaatttt
    13441 gacccaaaca tgcccgcctt tttcctttat tatgaaaaag gcgaacttgt tggtttatta
    13501 actgtctatg cagatgacca agatgtagaa gtgacgatac tggttcatcc aggtcatcgc
    13561 cgtcagggga ttgcgcgtgc attgtttact agttttgaga gagaaacagc ttctttcccc
    13621 attcggtcag tcacttttca gacagaacgt atttttttag agaatcatcc tgactttgcc
    13681 agtaactggg gactaatcga ggatgaagag acagaaactt ggttaggtaa ggatagaaga
    13741 ccttatccgt tagcaaatgt ttcccatctt gaagttttgt tagcagatag ttcgtatcag
    13801 gatcaaatta gtcaattaaa atttcaggca ttttcagagg aacatgaatc gagagaagtt
    13861 gtggatagat atgtcgctga agctctgaaa gatccagaaa gccgactata tattttatta
    13921 aaagctggtc aggttattgg aacttgtacg gttgatttat cgactaatac gaattacctc
    13981 tacggtttag caatattgga acctgaacgt ggaaaaggct atggaagcta cttagcaaaa
    14041 tccctcgtca accaactaat tgagcaaaat gacaaggaat ttcagattgc agtggaagat
    14101 agcaatgtag gtgccaaacg tttgtatgaa aaaattggct ttgtcaaaca gactcaggtg
    14161 gtttatctga atgagaaagg agcaagggat tccgaagtgt agagatattc ggactgaaat
    14221 ttacttgaac ttttagtgat gaaactaatt gttcttggat ttcagctttc ctgattatga
    14281 tttatgatta aaatctatga caccatgtct cgtgatttgc gagaatttgt cccgattgag
    14341 gacggcaaga tcaagatgta tgtttgtggg ccaacggtgt acaactatat ccacgtagga
    14401 aacgcccgtt cgacggtagc ttttgatacg attcgtcgct attttgagta ccgtgggtat
    14461 aaggttgcct atatttccaa ttttacagat gtggatgata agattatcaa ccgtgccagg
    14521 gaagaaggta tcacgcctca ggaggttgcg gataagtaca tcgctgcctt tcgtgaggat
    14581 gtgacggcat tgggcgtgaa acctgcgact cgccatccgc gtgtagtgga gtttatggca
    14641 gacatcatcc gttttgtgga agacttgatc gagaaaggct ttgcctatga gagtcaaggg
    14701 gatgtctatt tccgtgtaga aaaatcccac aactatgcta aattggctaa taaaaccttg
    14761 gaagatttgg agctaggtgc ttcaggtcgt accgatgaag aaacggctcg taaggaaaat
    14821 cctgtagact ttgctctatg gaaatcttcc aaaccaggtg agatttcttg ggatagtcct
    14881 tggggacctg gacgtccggg ttggcatatt gagtgttcag tcatgtcgac agagatttta
    14941 ggtgatacca ttgatatcca cggtggtgga gctgacctag agtttccaca ccacaccaat
    15001 gaaattgccc agtctgaagc taaaacaggc aaggcttttg ctaactactg gatgcacaat
    15061 ggctttgtca atatcgacaa tgtcaaaatg tctaagtcct tgggtaactt cattacggta
    15121 cacgatgccc ttaaaactct tgatgggcaa gtacttcgtt tcttctttgc gacccagcac
    15181 taccgtaagc ctatcaactt cacggaaaag gcagttcgcg atgccgagac caatctcaag
    15241 tatctcaaga atacttacga acaaccattt acaggaaatg tggatgccca agagttacaa
    15301 aactttaaag ataagtttgt agcagctatg gatgaagatt ttaatgctgc caacggtatc
    15361 acagttgtct ttgaaatggc caaatggatc aactcaggga actatgatgc aagtgtcaag
    15421 caagctcttg cagatatgtt agaaattttt ggaattgtct ttgttgagga agttttggat
    15481 gcagagattg aagacttgat tcaaaaacgc caagaggcgc gtgccaatcg tgactttgcg
    15541 acagcagacc aaatccgtga ccaattggtt actcaaggaa ttaagctcct tgataccaag
    15601 gatggagtga ggtggacacg tgattgatgt caatctcatt aacgggattg cgctagcctt
    15661 tgagggggat gcggtgtatt ctatgtatat tcgccgtcac ctcatcctca aaggtatgac
    15721 caaacccaat aaactccatc aagaagcaac taagtacgtg tcagccaagg ctcaggctcg
    15781 cctgattgct ctcatgttgg aggagcaggt cctaacggaa aaagaagaag aaatctacaa
    15841 acgtggccgc aataccaata gccacacaaa ggctaaaaat gcagatgtcg tgacttatcg
    15901 tatgtccacg ggatttgaag cggttatggg ctatctccat atgactgaga atctggaacg
    15961 tcttgagagt ttggtttcat ggtgcatcca aaaagtggag ggctagaaca tgagggcaaa
    16021 agaactacaa gactggtttc ctgaggctcg gatttcagac caaccagtag agaaagaggg
    16081 ctatctcacg ctccctttag cttctcagca gtggattttg ctggaggaag ctgggctcag
    16141 cgagcgtgaa aagcagttgg ttgccctttt gacccagcag gagcaggctc gttcgctaaa
    16201 cccttggtat tcctatctgg ttgagggcaa gggacaggca ccgcaagttt ttaaaaagat
    16261 tcagttggtt tattgccatc tttcttattt tcagcaggaa aatctggctt cttggctaga
    16321 tatgatgcgg actctttttc cgaattgtca gacagtgcta caggtcggag ctcaggatta
    16381 tgttttcgtg cttcaacaag acaaatacac ttctgtaaga gatattttaa gtgatacgat
    16441 tgaagcggtt gagtatgact ttggacttcg tctttctatc atgttgggtc aggtttggtc
    16501 tcagacggga catcaagccc tatcagactt aatcaaagct gagcgggatt tgttcaagac
    16561 atggtggcgt cagggtcacc aaggtgttca tactttttct cagctctatc tttggagtat
    16621 gggagaaaga ctcgtggact tgaagccaat caaggaatgt ctacaccaga tgattttgga
    16681 tcaagatcag attcaggaaa tcattctctc tctttgggaa aatagtgctg ttctcactaa
    16741 aacagcccag caactctatc tgcaccgcaa ttctctccaa tacaagattg ataaatggga
    16801 agagttgaca gggcttcagt tgaaagagtt gaccgacctg accttgtgtt atcaattgat
    16861 tttaggttct ttgtcaacta tagttggttt gtaaagaagt taatatttgg agaagaggat
    16921 tgccatcttc tccattttta tgtgcagagt tatagtggct tgatgctggg aaagtacact
    16981 gtgactgcta aaacattcct agaagctgct ttgatttccc taatctattt atgcaaattt
    17041 tatgttattt tactataaca gttgttgcta agccaaataa tagtggggaa gttcatttag
    17101 acgtaagcat tgaagataat cagggaggta gtgggtataa tttcagttct gtttcaagta
    17161 gctcacaaac agctaaatat gaaggaactg tttataataa caattcatca ttatatataa
    17221 cgattgataa aacgtctgat gcaacagctc ttttgaaatt aaagttgaat aatgttgata
    17281 atcaacctgc tactgaagtt cctagttcag gaattactgt aaaattaaat gctaaagata
    17341 atgctggaaa ctggacaagt gcttcgaata aaaaagaagt aacagtaaaa attgtttctg
    17401 ctaaaccgac atatccagac aaaatcttag tgaaaaatcc tgataatata aaagatacag
    17461 aaaaaatgcc attattgaaa aattgaaaga ggcaaataaa aatcatccag caggagctcc
    17521 aacctttgct aaaggtgaag gagagcatgc aaatgatatt gtagcaactt attcagatgg
    17581 tacaacttat tatgtaccgt taaatgatgt gacaaaatat gcgaggtagt ggctgtacca
    17641 ctcacttatt cacctccccg tgatttgtag tagtgatagg ctttctcact attattataa
    17701 aacaaaataa agatcacaac actttttcat tctgtgttgt gccttgagtg aaacgaaagg
    17761 aatgaattat aaatatgaaa agtatagtca ctagcataga tgagcgcttg cgtactcgcc
    17821 tacgagtgat tatctggaag caatggaaga agaaatcgag acgattatgg ggattgctta
    17881 agttaggggt tcctaaatgg atagcagata aggtatctgg ctggggcgac cactatcaat
    17941 tatattaaaa tgaaataaga ataggacgaa tcgatcaggg aagtcaaatc gatttctaac
    18001 aatattttag aagtagaggt atattattct agtttcaatc tactatagta tctcagaagt
    18061 cggtacttaa acgtgctata tcaaaaccag tccttg
//
LOCUS       DAVMBH010000040        17906 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVMBH010000040 DAVMBH010000000
VERSION     DAVMBH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.040"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(210..1145)
                     /locus_tag="VYP30_001569"
     CDS             complement(210..1145)
                     /locus_tag="VYP30_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1808540.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLIQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1142..2002)
                     /locus_tag="VYP30_001570"
     CDS             complement(1142..2002)
                     /locus_tag="VYP30_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1808541.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2110..4272
                     /locus_tag="VYP30_001571"
     CDS             2110..4272
                     /locus_tag="VYP30_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1808542.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNDYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4364..5623
                     /locus_tag="VYP30_001572"
     CDS             4364..5623
                     /locus_tag="VYP30_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1808543.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATDGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKIMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATAKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5637..6503
                     /locus_tag="VYP30_001573"
     CDS             5637..6503
                     /locus_tag="VYP30_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1808544.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LFWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6517..7350
                     /locus_tag="VYP30_001574"
     CDS             6517..7350
                     /locus_tag="VYP30_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1808545.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7661..9103
                     /gene="gtfA"
                     /locus_tag="VYP30_001575"
     CDS             7661..9103
                     /gene="gtfA"
                     /locus_tag="VYP30_001575"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1808546.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFRDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRSTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVVEIDLQNQTYRVIENGVEVSF"
     gene            9241..10434
                     /locus_tag="VYP30_001576"
     CDS             9241..10434
                     /locus_tag="VYP30_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1808547.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMNSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11119..13098
                     /locus_tag="VYP30_001577"
     CDS             11119..13098
                     /locus_tag="VYP30_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1808548.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLSPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13165..14661
                     /locus_tag="VYP30_001578"
     CDS             13165..14661
                     /locus_tag="VYP30_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808549.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14661..15587
                     /locus_tag="VYP30_001579"
     CDS             14661..15587
                     /locus_tag="VYP30_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808550.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15596..16663
                     /locus_tag="VYP30_001580"
     CDS             15596..16663
                     /locus_tag="VYP30_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808551.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPHHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16674..17600
                     /locus_tag="VYP30_001581"
     CDS             16674..17600
                     /locus_tag="VYP30_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808552.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17675..>17906)
                     /locus_tag="VYP30_001582"
     CDS             complement(17675..>17906)
                     /locus_tag="VYP30_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808553.1"
                     /translation="HPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLIKLIKRN
                     AFGFRNFENFKKRIFIALNIKKERTKFVLSQA"
BASE COUNT         5279 a         3173 c         3747 g         5707 t
ORIGIN      
        1 catatgaatc tttctaatga tggttttgtc gcttttcatt ataggtcata tgggactttt
       61 tttctacaac aaaataggct ccataatatc tataagggat ttacccacta caaatattat
      121 agagacaata aaacttcaga tccgtaaaac ttaattgaat tactaatctg aagttatttt
      181 tatatcgttt atattataat tgtgttattt tacttccaac tattgagaga aatttcgcca
      241 ctatttagcc agatttcttt tccgttatca cattgaatta aaagttttcc attttctgag
      301 atgtctttag caagtccctt gtagtctttt tgctctagtg tgaaagtgac ttcttttcct
      361 agaatgaatg actgtttttt gtataggtat aatagctctt ctgctggtgt ttcgaagaaa
      421 gcacgccaga tttctatgat caattcattc cttgttatag gagctgtagc tttaaataag
      481 ctggcagctt tttcttttaa ttcctgaggg aagtctttaa tagtgaaatt gatacctact
      541 ccaataatga tatctgtgac taagccagtt tctacagagg tcattgcttc agtaaggatt
      601 cctccaattt tatgattgtt tagatagata tcattgaccc attttatgtc gacatctatt
      661 aaagttaggt tcttaatagc tttgtagaca gctccagcta caagtagtgt gtaggatggt
      721 aatttgtcat aggggagatt tggtttaaga tggagtgtca tataaatacc accttgtggt
      781 gagtagaagg aacgttgaaa acggcctcgg cctgctgttt gataggaagc tagatagagg
      841 gtatttgctt catggcctaa atcaattgct tcttttgcat ctagttgtgt tgattttgtt
      901 tcgggtttaa agctgacttt aattggaaga ttttcttcta gaatctctgg aagaataagg
      961 tcaccattca tcagtttata tcctctattt ttgatactat caatttcaat gccttcttgt
     1021 tctagtcgct tgatagcttt ccaaattgat gttcggctta gggatagttt ttctgcgatt
     1081 ttttctccgc tgatatagtc ggtttcttta gataggattt ggtagacagc ttggtaggat
     1141 ttcataatgt tgcctttctc actagttggt attgagagta ttcttttctt gtatgacttg
     1201 gagtctgatt aaagtattgt ttataagctt tcgaaaaatg gagtggatct gaaaaaccta
     1261 ccgagtatgc aattaccttg atggactctt gggtattttc gagaagttgt ctagctcggt
     1321 gcattcgaac gtagagtagg tattctttgg gtgataaggt attaaattct ttgaatacgc
     1381 ttgataagta gcttctgtga acggatagtt cttttgctaa atcttgaatt gtaagtgatt
     1441 gaggatagtg gctatcaatt aatcgtttgc attcaagata gagttggtgg gttgatgaaa
     1501 tattcttttt tttctgattg ggagcaatag ttcccagatg aaacatcagt tcatgaagtt
     1561 gtcccatgat atggagttga gctaattcac ttgattttgt aatctgagcg aagcggacaa
     1621 tgtctgagat gagttttgca gtagtctggg tatgacaagt ttcagattgg atgagatagg
     1681 attgatcaga aatttgagaa agagcaaaat aatcagggga tttccctcca gtgattccta
     1741 accagtagta ggcccaaggt tctttactat ctgcttgata aaaggttagt tcctctggtt
     1801 ttaatagaaa gaaatctcct tcttttaaat caacaatttt acccttgtaa taaaattttc
     1861 cttgtccttt agtaatgtaa tgtagaacgt atgtatcacg aatggctgga ccaaaagagt
     1921 aattaggtgt gcattcctca tatccataaa agcttagggc aaggtcgatt gttccagtct
     1981 ggtattctga aaaaactaac atgtgctacc tcctacctaa cattttacca tattcttgag
     2041 acatttttct attttggaaa gcgatttcag gtgataaaat ataatcaata aagtgatgag
     2101 gtgaagtaaa tgggagttag gatagagaat aatctatttt atgttgagag taaaaatcta
     2161 agtttgatta ttgaaaatcg aaatgactac ttacttttga aacatttagg aaagactatt
     2221 aagaactata aaggttccaa tagtgtttat gaacgagacc atgccttttc aggaaatcca
     2281 acggctacta atcgaacctt tagtttagat actcagcgac agatttttgg acaacatggc
     2341 ttaggagatt ttaggaaacc aaccatacag gttcagcata gtgtaactga agtaacagac
     2401 tttcgatttg tagaagcaaa gattttaaaa ggtcagaatg gtccacaggg cttaccttct
     2461 ccacatagca tggacgatac agagactctt gtcttaatgt tagaagattc taaggctcaa
     2521 cttagtctga ctttgtatta tactactttt aataatgatg cgactattgc tagctacagt
     2581 aaattagata ataatagtaa tcaggaagtt gtcatccata aagatttttc ttttatggct
     2641 gattttccag ctgcagatta cgaaatagta actctgcagg gtgcttatgc tcgtgaaaag
     2701 actgttagac gtcaacaggt agaacaagga atcttttcga ttagctcaaa ccgaggtgct
     2761 tctggtcatg ctcaaacacc agctcttcta ctatgcgaac aaggagtcac agaggatgct
     2821 gggaatgtgt ttgctattca actaatgtat agtggcaact ttgaagcttt tgttcaaaaa
     2881 aatcaattga atgaagttcg ggtggctatt ggcattaatc cagaaaactt ttcttggaag
     2941 ttagcccctg aggaatactt tgaaacaccg gtagctttag tgactcattc agatcaggga
     3001 ttaactggta ttagtcatga aagtcagaat tttgtactga agcacattat gctaagtgaa
     3061 ttttctaaaa aagaacgtcc aattctaatc aataactggg aagctactta ctttgacttt
     3121 cagagagaaa aactgttaga gttagcagat gaagctaaga aagttggcat tgaacttttt
     3181 gtattagatg atggttggtt tggcaatcgt tttgatgata atcgtgcttt aggtgattgg
     3241 gttgttaatg aggaaaaact gggtggaagt ctagaaagtc tgatttcagc tatccatgaa
     3301 agaggtttgc agtttggact ttggttagaa cccgaaatga tttctgtaga tagtgatttg
     3361 tatcgtcaac atcctgactg ggctattcag gttcctgatt atgagcatac ttattctcgg
     3421 aatcaattag tacttaatct tgccaatcct caggtagtag aatacttgaa aagtgtctta
     3481 gatcaactcc tatcttatca tgagattgat tacattaaat gggatatgaa ccgcaatatc
     3541 actaagctag ggaatggatt aacttatcta gagacacaga tgcaatctca tcagtacatg
     3601 ctggggcttt acgaactcgt ttcttatctg acagagaagc acagccatat tctctttgag
     3661 tcctgctctg gtggtggtgg acgaaatgat cttggtatga tacgctattt cccacaagtc
     3721 tgggctagtg ataatactga tgccattgca cgtttaccaa ttcaatacgg ttcatcctat
     3781 ctctatccaa ccatttctat gggggctcat gtgtcagcag taccgaatca tcagatggga
     3841 cgaatgacac cattagaaac acgtggccat gtagcaatga tgggaaattt gggctatgag
     3901 cttgatttga caaatttatc agatgaagag aaagctacga ttgctaatca ggtgaacttg
     3961 tataaagaat tacgaccagt agttcagtta ggacagcagt atagactaat taatcctgat
     4021 actgcatcca atgaagcagc tgtacaattt aattacggaa atcaaacgat tgtaacctac
     4081 gttcgcgttt tatctgttgt agagaccatg gaaacaactt taaaattaaa agatttggat
     4141 gaagagggac tatataaatt acaggaaaat ggcgaagttt actcaggtgc agaactaatg
     4201 tatgcgggct taactgttat cttatcccaa ggagattttt tgagtagaca gtatattttt
     4261 agaaaactat gatatgtact gaccccaaaa gttagattta ttctatctaa cttttgaggt
     4321 gcagtttgat aagggtgtat aaatttataa aggaggcttt ctaatggaat ggtataaaaa
     4381 aatcggactt cttgcaacta caggtttagc tttgtttggg ctcggtgctt gctccaacta
     4441 tggtaaatct gcggatgaca cagtgaccat cgagtatttc aaccagaaaa aagaaatgac
     4501 caaaaccttg gaagaaatca ctcgtgattt tgagaaggaa aaccctaaga taaaggtcaa
     4561 agtcgtcaat gtaccaaatg ctggtgaagt attgaagaca cgcgttctcg caggagatgt
     4621 gcctgatgtg gtcaatattt acccacagtc catcgaactg caagaatggg caaaagcagg
     4681 tgtctttgaa gatttgagta acaaagacta cctgaaacgc gtgaaaaatg gctacgctga
     4741 aaaatatgct gtaaacgaaa aagtttacaa cgttcctttt acagctaatg cttatggaat
     4801 ttactacaac aaagataaat tcgaagaact gggcttgaaa gttcctgaaa cctgggatga
     4861 atttgaacag ttagtcaaag atatcgttgc taaaggacaa acaccatttg gaattgcagg
     4921 tgcagatgct tggacactca atggttacaa tcaattagcc tttgcgacag caacagatgg
     4981 aggaaaagaa gcaaatcaat accttcgtta ttctcaacca aatgccatta aattgtcgga
     5041 tccgattatg aaagatgaca tcaagatcat ggacatcctt cgcatcaatg gctctaagca
     5101 aaagaactgg gaaggtgctg gctataccga tgttatcgga gccttcgcac gtggggatgt
     5161 cctcatgaca ccaaatgggt cttgggcgat cacagcgatt aatgaacaaa aaccgaactt
     5221 taagattggg accttcatga ttccaggaaa agaaaaagga caaagcttaa ccgttggtgc
     5281 gggagacttg gcatggtcta tctcagccac cgccaaacat ccaaaagaag ccaatgcctt
     5341 tgtggaatat atgacccgtc cagaagtcat gcaaaaatac tacgatgtgg acggatctcc
     5401 aacagcgatc gaaggggtca aacaagcagg agaagattca ccgcttgctg gtatgaccga
     5461 atatgccttt acggatcgtc acttggtctg gttgcaacaa tactggacca gtgaagcaga
     5521 cttccatacc ttgaccatga actatgtctt gaccggtgat aaacaaggca tggtcaatga
     5581 tttgaatgcc ttctttaacc cgatgaaagc ggatgtggat taggagtaga gagactatga
     5641 aaaaagtatt acaaaaatat tgggcatggg cttttgtggt catccccctc ttgttacaag
     5701 caattttctt ctatgtgccg atgtttcaag gagcctttta cagttttacc aactggacag
     5761 gattgactta taactacaaa tttgtcggct taaacaactt taagctcctc ttcatggatc
     5821 caaaattcat gaatgcgatt ggctttaccg caatcattac gattgccatg gtggttggtg
     5881 agattgcact cgggatcttc attgcgcgtg tcttgaattc taaaatcaaa ggccaaacct
     5941 tcttccgtgc ttggttcttc ttcccagctg ttttatctgg tttgacagtg gctttgatct
     6001 tcaagcaagt cttcaactac ggtcttccag cgattgggaa tgcccttcat attgaatttc
     6061 tccaaaccag tcttttaggg actaagtggg gagcaatctt tgcggctgtc tttgtccttt
     6121 tttggcaagg ggtggctatg cccatcatca tcttcctagc tggtttgcaa tctattccaa
     6181 ctgagattac agaggcagca aggattgatg gtgcgactag caagcaagtt ttctggaaca
     6241 ttgaattgcc ttacttgcta ccaagtgtct ctatagtctt tatcctagcc ctaaaaggtg
     6301 ggctgactgc ctttgaccaa gtctttgcca tgaccggtgg tggtccaaac aatgccacaa
     6361 cctcacttgg gctcttggtt tataactatg cctttaaaaa caaccaattc ggttatgcca
     6421 atgccattgc cgtaatcttg ttcttcttaa ttgtagtgat ttcgatcatc caattgagag
     6481 tatctaagaa atttgaaatt taagaggaga agcatgatga aacaagatga aagaaaagcc
     6541 ctgattggca aatacattct attgattcta ggatcggttc tgattttagt gccgctcctt
     6601 gctaccctct ttagttcctt caaacccact aaggatattg tagataattt ctttggtttt
     6661 ccaaccaact tcacatggga caactttagc cgtctcttag ctgatgggat tggaggctat
     6721 tattggaact ctgtcgtcat cactgtcttg tctttacttg cagtaatgat ctttatccct
     6781 atggcagcct actccatcgc tcgcaatatg agtaaaagaa aagcctttac catcatgtat
     6841 accctcttaa tcctcggaat cttcgtacct ttccaagtca tcatgattcc gattacggtt
     6901 atgatgagta aactcggttt ggctaatacc tttggtttga tcttgctcta cttgacctat
     6961 gcgattccac agaccctctt tctctatgtt ggctatatca aaatctcgat tccagaaagt
     7021 ctggatgaag cagcagagat cgatggggct aatcaattta caacctattt ccgcatcatc
     7081 ttcccaatga tgaaaccgat gcatgcgaca accatgatca tcaatgccct ttggttctgg
     7141 aatgacttca tgttgccact ccttgtcttg aaccgggatt ccaaaatgtg gactctgcct
     7201 ttgttccaat acaactacgc aggccaatat ttcaacgact acggaccaag ctttgcctct
     7261 tacgtggtcg gcattatcag tatcaccatt gtctatctct tcttccaacg ccatatcatt
     7321 tcaggaatga gcaacggggc agtgaagtaa tactcaatga aaatcaaaga gcaaactagg
     7381 aagctagccg caggctgtac ttgagtacgg taaggtgaag ctgacgtggt ttgaagagat
     7441 tttcgaatag tataagaaga gctcatggaa tctatagtct ttgacacaga ggaagagttc
     7501 agcttgttga taattctatg tagaaaacaa gaaagtagta ctttgtttat cacagtctat
     7561 attagtacga gtttgatgat aaatagagat ttaaaatgaa ttttatttat gaagccagat
     7621 catatgagac ttggcttcaa ttagaaaaag gagagtaatg atgccaattc aaaataaaac
     7681 catgttgatt acctattctg atagccttgg aaataatctt aaagacttat atgataattt
     7741 ggaagagcat tttcgagatg ctattggagg agttcacctt ttaccatttt tcccatcaac
     7801 aggtgatcgt ggatttgcgc cagttgacta cgacgaagtg gactcagctt ttggtgattg
     7861 ggaggatgtt aagcgtttag gtgagagata ttatcttatg tttgatttta tgattaatca
     7921 tatttctcgt caatccaagt attataagga ctatcaagaa aaacatgaag ccagtgaatt
     7981 taaagctctc tttttaaact gggataagtt ttggccagaa aaccgttcga cacagtctga
     8041 tgtagattta atttacaagc gtaaggatcg tgcaccaaag caagagattg tgtttgaaga
     8101 tggttcagtg gaacatttgt ggaatacctt tggtgaggag cagattgatc ttgatgtgac
     8161 caaagaagta actatggaat ttatccgtaa gaccattcag cacttggcaa gtaatgggtg
     8221 tgatttgatt cgtctagatg cctttgctta tgcagtgaag aaattggata ctaatgattt
     8281 ctttgtggaa ccagatattt gggatttatt ggacaaagtt cgagatatcg ctgctgagta
     8341 tgggacagag cttttacctg agattcatga acactattcg attcagttta aaatagcaga
     8401 ccatgattac tatgtttatg attttgctct tccaatggtg acactttata ctctttacag
     8461 ttccagaaca gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc aatttacgac
     8521 gctagatacc catgatggga ttggagtagt agatgtcaag gatatcctga ccgatgagga
     8581 gattgactat gcttcaaatg aactctataa ggttggagcc aatgtcaaac gtaagtactc
     8641 tagtgccgag tataacaact tagatatcta ccaaatcaat tcaacctact attcagcgct
     8701 tggagatgat gatgtcaagt attttctcgc tcgtctaatt caagcttttg ccccaggtat
     8761 tcctcaggtt tactatgtgg gtctattagc aggcaagaat gacttgaaat tattagaaga
     8821 aactaaagaa ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa tagcaaaaga
     8881 agtgcaacga cctgttgtga aggcccttct caatctattt tctttccgta accgttcaga
     8941 agcctttgat ctagaaggga ctactgagat agagacacca acagctcaca gcattgtaat
     9001 caaacgtcaa aataaagata agtccgtaac agcagtagta gaaattgatt tgcaaaatca
     9061 gacttatcgg gtaattgaga atggagttga agtatcattt tgaagccttg atatggtgga
     9121 taaaataggg tttttatttt ggaaaacgtt tcctttgttt tcaaattgct aaaaaagtgg
     9181 tacaatatag gatagcttac tattatctga atcagctgat ttggagagaa aggattcatt
     9241 ttgaaatcaa taggctttat tgaaaagctg aaggggttgt ctagtaaaga gctgatttta
     9301 ttgggaatta tcctaagtat ctttttaccc ttttatcttt ttgtagttgt actctgttta
     9361 tatattatca gtttgatttt tacaggagac atgaaaagta ttcttcagaa aatgggggag
     9421 catccgatgc tgcttctttt tcttagctat agtactgtta tatccattct tgcacaaaat
     9481 tggatgggtc ttgtggcttc agtaggaatg tttctattta ctattttctt tttgcactat
     9541 cagtcgattt tatcccataa attctttcga ttgattttgc agttcgtctt gtttggtagt
     9601 gtcttgtcag ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa atttaactat
     9661 gcttttcttt cacccaatat gcaggtgtgg catcagaacc gggcagaagt gaccttcttt
     9721 aatcctaatt attatggaat tatttgttgt ttctgtatta tgattgcttt ctatctgttt
     9781 acaacgacca agttgaattg gttgaaagta ttctgtgtga ttgcaggctt tgttaatctc
     9841 tttggtttga actttactca aaatcgaact gcctttcctg ctattatcgc tggagcaatt
     9901 atctatctct ttacgactat taaaaactgg aaggcctttt ggcttagtat tggggtcttc
     9961 gcgattggtt tgagtttcct cttttctagt gatttgggag ttcgaatggg tactttagac
    10021 tcttctatgg aagaacgcat ttctatctgg gatgctggga tggccttgtt taagcaaaat
    10081 cctttttggg gtgaagggcc attgacctat atgaactctt atcctcggat acatgctcct
    10141 tatcatgaac atgcccacag tctttatatt gatacgattc tgagttacgg aattgtaggg
    10201 actattttat tagttttgtc ttctgttgct cctgttcgct tgatgatgga tatgagtcag
    10261 gagtcgggga aacgtccgat tatcggcctt tatctatctt tccttacagt ggttgctgtg
    10321 cacggaattt ttgacttggc tctcttctgg attcagtcag gctttatttt cttgctagtt
    10381 atgtgcagta ttccattgga gcatcgaatg ttggtatcgg acatgacgga ttaagtttta
    10441 taagtttgaa atcttctacc ttgggtagga gattttttat acgatgggca tgtcgtgcat
    10501 ctgaggtgta agtcctctgt agggctccac taccggtgaa tacaatagcg ctccccaagc
    10561 ctgactatcg tgaggtagcg gattaaaatg gtctggggat agatcgtttt aagtctgacg
    10621 caggaaataa gaattgtcag agaaagcaat agtgaaatcg taggctatga atagaaacgt
    10681 gatagcgagg agcatatagt ggataaggta gcgagaaatt ttaaagtata aaagatagtc
    10741 ttaatctata tatgtaaatc acaaaagtaa ttgaattcgg gataaggttg gtgtgaaaag
    10801 acatagtaaa ctgaatcttg aatactagaa tgatacttct acaatattgt tataatttaa
    10861 tttgaattcc aaaatcacat tgttccgtcc gtatttcatt ttactgtatg tcttcctaaa
    10921 ctccaaagtt tctgcgtcaa atttcctatt ttcactgtag tctttgacac ttcgaacgac
    10981 aatttgaatc atatattcaa aaaaaatgaa aaatttgtgc caacaagcct aaatattctg
    11041 aaaatttgtt tgatttttaa tggataatgt gatataatgg ttgtcaatct ataattcaca
    11101 taaacagagg agtagaaaat gaaaaaaaat cgtgtatttg ctacagcagg tcttgtttta
    11161 ttagcagcag gtgtacttgc agcatgcagt tcttcaaaat catctgattc atcagcccct
    11221 aaagcttatg gctatgttta tacagcagac ccagaaacct tggactacct gatttcaagt
    11281 aaaaatagta caacagtagt gacttcaaat gggattgatg gtttattcac taacgataat
    11341 tacggtaatc tttctcctgc agttgcagag gattgggaag tctctaagga tggtttgacc
    11401 tacacttata agattcgtaa aggggttaaa tggtttacct ctgatggaga agaatatgca
    11461 gaggtgacgg ctaaagattt cgtgaacggt ttaaaacacg cagcagataa aaaatcagaa
    11521 gctatgtatt tagctgaaaa ttcggttaaa ggcttggcag attatctatc aggaacttca
    11581 acagattttt caacagttgg tgtcaaggcg gttgatgatt atacgttaca atacactttg
    11641 aaccagcctg aaccgttctg gaactctaag ttgacctatt ctattttctg gcctctgaat
    11701 gaagaattcg aaacatcaaa aggaagcgat tttgctaaac caacagatcc gacatccttg
    11761 ctttataatg gtccattctt gttgaaaggg ttgactgcaa aatcttctgt agagtttgta
    11821 aaaaatgagc aatattggga taaagaaaat gtccacctag atactatcaa tctagcttac
    11881 tatgatggat cagatcagga gtcgctagag cgtaacttca ctagtggagc ttatagttat
    11941 gcccgtcttt accctaccag ctccaactat tctaaggttg cagaagaata caaggacaat
    12001 atctattaca cacaatcagg ctctgggatt gctggtctgg gtgtgaatat tgatcgccaa
    12061 agttacaact atacttctaa aactacagat tcagagaaag tagctactaa gaaggcattg
    12121 cttaacaaag atttccgtca agccttgaat tttgctcttg atcgctcagc ttactcagct
    12181 caaatcaatg gtaaagatgg agcagcttta gcagttcgta atttatttgt aaaaccagac
    12241 tttgtttcag ctggtgagaa gacctttggt gatttagtcg ctgctcaact tcctgcttat
    12301 ggtgatgagt ggaaaggtgt gaatttagct gatgggcagg atggtttatt caatgctgac
    12361 aaggccaagg cagagtttgc gaaagctaag aaagctttag aagcagacgg cgttcagttt
    12421 cctattcatc tggacgttcc agtagaccaa gcatcaaaaa actatatatc tcgtattcag
    12481 tcctttaaac aatctgtaga aacagttctt ggtgttgaaa atgtcgttgt tgatattcaa
    12541 caaatgacaa gtgatgaatt ccttaatatt acttactatg ctgccaatgc ttcatctgag
    12601 gattgggatg tatcaggagg agtttcatgg gggccagact atcaagaccc atctacttac
    12661 ctggatattt taaaaacaac tagcagtgaa actacaaaaa catatttagg atttgataat
    12721 ccaaatagcc cttcagtagt tcaagttggt ttgaaagaat acgataaatt agttgatgaa
    12781 gctgccaaag agacaagcga cttgaatgtc cgttatgaaa aatatgcagc ggctcaagca
    12841 tggttgacag atagttcact ctttattcct gctatggctt cttctggtgc agcaccagtg
    12901 ctttcacgaa ttgttccatt tactggagct tctgcgcaaa caggctctaa ggggtcagat
    12961 gtttacttca aatatttgaa attacaagat aaagtggtga ctaaggaaga gtatgaaaaa
    13021 gctcgtgaaa aatggttgaa agaaaaagct gaatcaaatg agaaagctca aaaagaattg
    13081 gcaagtcatg tgaagtaaat aatttctaat agaactttct ctccatgagg agaaggttct
    13141 tttgggattt ttaaaggaaa taatatgaaa aaatatattt ttatgcgtgt tttgcggtca
    13201 ttggtttcga ttttcttagt aacgactttg acctacacga ttatctatac cttggttcct
    13261 cgaaaattga ttttcaagca ggatcctaac tataataaaa ttgcgacaac ggctgataaa
    13321 cgtgataact atgaaaatac tgtgtttgag cgtatgggct acattgagta ttacgatact
    13381 aaagagttgc aagaaaaggc aagtagcatg gattcttctg taacagtaga agcaaatgcg
    13441 accaataaag ctatttatga aaagtacatc aatcaattag gtcatggttg gactttggga
    13501 gaatttactg aaagtggtca attctatgct actcgtgaaa ttccaatttt tgaacgtgtt
    13561 tttcacttct atgctaactt gattgacatt gaccatacaa ataaaatcca agaccctgaa
    13621 aatccagact tgaaacgcta ccttcgtttt gaaaatgatc cagctatcgg atggtcattg
    13681 gtcggttcag gaactaaaca taaatatctc ttgtacttta acagtcagtt cccatttgtt
    13741 catcaaaact ttgtgaactt gaatttaggt gactcttacc caacctatgc taatacacca
    13801 gttcttcagg ttattactca aggtcaagga caaaccaaaa ctgcccaagt tcagttccca
    13861 acaggtaaga aaacgtcttc tgtaaatatt tactcaagaa cctacaagtc acctagtcag
    13921 gctgactctc gtgaagtagc tagctatggg aaagatgatc cttatacagc gactgaaagt
    13981 aattaccaat atccatctat gattgtcagc tctgctatta ctggtttgat tggtttggtt
    14041 cttgcctatg ctcttgccgt gccacttggt tcagccatgg ctcgtttcaa gaacacttgg
    14101 attgatagcc tctcaacagg gactttgacc ttcttgcttg ctcttccaac gattgccttg
    14161 gtttacatcg ttcgattgat tggatcatct attgcccttc cagattcatt ccctatcttg
    14221 ggagctggag attggcgttc ttacgtttta ccagcagtca tccttggttt gttgggtgct
    14281 cctgttacag ccatttggat tcgtcgttac atgattgact tgcaatctca agactttgtt
    14341 cgtttcgctc gtgcaaaagg tttgtctgaa aaagaaattt caaacaaaca catctttaaa
    14401 aatgccatgg ttccgctggt ttcaggaatt cctggtgcca ttattggggt tatcggtggt
    14461 gcaaccctta ctgaaacagt cttcgccttc ccaggtatgg gtaaaatgtt gattgactct
    14521 gtaaaagcat ctaataactc tatggtcgtt ggtcttgtct tcatctttac atgtatttct
    14581 atcttctcac gtcttttggg agatatttgg atgactatta ttgacccacg tattaaattg
    14641 actgagaaag gaggcaaata atgtctacaa tcgataaaga aaaatttcag tttgtaaaac
    14701 gtgacgattt tgcctctgaa actattgatg cgccagcata ttcttactgg aaatcagtgt
    14761 ttaaacaatt tatgaagaaa aaatcaactg tagtcatgtt gggaatcttg gtagccatca
    14821 ttttgataag tttcatctac ccaatgtttt ctaagtttga tttcaatgat gtcagcaagg
    14881 taaacgactt tagtgttcgt tatatcaagc caaatgcgga gcattggttc ggtactgaca
    14941 gtaacggtaa atcgctcttt gacggtgtct ggttcggagc tcgtaactcc atcctcattt
    15001 ctgtgattgc gacagtgatt aacttggtta tcggtgtttt tgtcggtggt atttggggta
    15061 tttcaaaatc agttgaccgt gtcatgatgg aagtttacaa cgtcatctca aacatcccac
    15121 ctcttttgat tgttattgtc ttgacttact caatcggagc tggattctgg aatctgattt
    15181 ttgccatgag cgtaacaaca tggattggta ttgccttcat gatccgtgtg caaatcttgc
    15241 gctatcgtga cttggaatac aacttggcgt cacgtacttt gggaacacca accttgaaga
    15301 ttgttgccaa aaatatcatg cctcaattgg tatctgttat tgtgacaacc atgactcaaa
    15361 tgcttccaag ctttatctca tacgaagcct tcttgtcttt cttcggtctt ggattaccga
    15421 ttacagtgcc aagtttgggt cgtttgattt cggattattc acaaaacgta acaaccaatg
    15481 cttacttgtt ctggattcca ttgacaaccc ttgtcttggt atccttgtcc cttttcgtag
    15541 ttggtcaaaa cttagcggat gctagtgatc cacgtacaca tagataggag tagaaatgac
    15601 aaaagaaaaa aatgtaattt tgactgctcg cgatattgtc gtggaatttg acgttcgtga
    15661 caaagtattg acagccattc gcggcgtttc ccttgaacta gttgaaggag aagtattagc
    15721 cttggtaggt gagtcaggat caggtaaatc tgttttgaca aagaccttca caggtatgct
    15781 cgaagaaaat ggtcgtattg cccaaggtag tattgactac cgtggtcagg acttgacagc
    15841 tttatcttct cacaaggagt gggaacaaat tcgtggtgct aagattgcga ctatcttcca
    15901 ggacccaatg actagtttgg accccattaa aacaattggt agtcagatta cagaagttat
    15961 tgtaaaacac caaggaaaaa cagctaaaga agcgaaagaa ttggccattg actacatgaa
    16021 taaggttggc attccagacg cagatagacg ttttaatgaa tacccattcc aatattctgg
    16081 aggaatgcgt caacgtatcg ttattgcgat tgcccttgcc tgccgacctg atgtcttgat
    16141 ctgtgatgag ccaacaactg ccttggatgt aactattcaa gctcagatta ttgatttgct
    16201 aaaatcttta caaaacgagt atcatttcac aacaatcttt attacccacg accttggtgt
    16261 ggtggcaagt attgcggata aggtagcggt tatgtatgca ggagaaatcg ttgagtatgg
    16321 aacggttgag gaagtcttct atgaccctca ccatccatat acatggagtc tcttgtctag
    16381 cttgcctcag cttgctgatg ataaagggga tctttactca atcccaggaa cacctccgtc
    16441 actttatact gacctgaaag gggatgcttt tgccttgcgt tctgactacg caatgcagat
    16501 tgacttcgaa caaaaagctc ctcaattctc agtatcagag acacattggg ctaaaacttg
    16561 gcttcttcat gaggatgctc caaaagtaga aaaaccagct gtgattgcaa atctccatga
    16621 taagatccgt gaaaaaatgg gatttgccca tctggctgac taggaggaag gaaatgtctg
    16681 aaaaattagt agaaatcaaa gatttagaaa tttccttcgg tgaaggaagt aagaagtttg
    16741 tcgcggttaa aaatgctaac ttctttatca acaagggaga aactttctcg cttgtaggtg
    16801 agtccggtag tgggaaaaca actattggtc gtgctatcat cggtctaaat gatacaagta
    16861 atggagatat catttttgat ggtcaaaaga ttaatggtaa gaaatcgcgt gaacaagctg
    16921 cggaattgat tcgtcgaatc cagatgattt tccaagaccc tgccgcaagt ttgaatgaac
    16981 gtgcgactgt tgattatatt atttctgaag gtctttacaa tcaccgttta tttaaggatg
    17041 aagaagaacg taaagagaaa gttcaaaata ttatccgtga agtaggtctt cttgctgagc
    17101 acttgactcg ttaccctcat gaattctcag gcggtcaacg tcaacgtatc ggtattgccc
    17161 gtgccttggt catgcaacca gactttgtta ttgcagatga gccaatttca gccttggacg
    17221 tttctgtacg tgcccaagtc ttgaacttgc tcaaaaaatt ccaaaaagag ctcggcctga
    17281 cctatctctt catcgcccat gacttgtcgg ttgttcgctt tatttcagat cgtatcgcag
    17341 ttatttacaa gggtgttatt gtagaggttg cagaaacaga agaattgttt aacaatccaa
    17401 ttcacccata tactcaagcc ttgctttcag cggtaccaat cccagatcca atcttggaac
    17461 gtaagaaggt cttgaaggtt tacgacccaa gtcaacacga ctatgagact gataagccgt
    17521 ctatggtaga aatccgtcca ggtcactatg tttgggcgaa ccaaaccgaa ttggcacgtt
    17581 atcaaaaagg actaaactag taatggtttt ataatttcca tgtcaatttt tatggaaatt
    17641 aggctctttg tcaactgtag tgggttgaag tcagctaagc ttgagaaagg acaaatttcg
    17701 tcctttcttt tttgatgttc aaagcgataa aaatccgttt tttgaagttt tcaaagtttc
    17761 gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgct tccagtttgg
    17821 cattagaata gtgtagttga agggcgttga taatcttttc tttatctttg aggaaggttt
    17881 taaagacagt ctgaaaaata ggatga
//
LOCUS       DAVMBH010000041        17253 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVMBH010000041 DAVMBH010000000
VERSION     DAVMBH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17253
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.041"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..347
                     /locus_tag="VYP30_001583"
     CDS             <1..347
                     /locus_tag="VYP30_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808554.1"
                     /translation="PWIKYLEISSFILTIFPSILYGTVDNHVLTLIFLIKICVDTTIK
                     FLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSVLLLFSNFSVPFI
                     KEKEYELFKNSK"
     gene            1486..1725
                     /locus_tag="VYP30_001584"
     CDS             1486..1725
                     /locus_tag="VYP30_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808555.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1710..1988
                     /locus_tag="VYP30_001585"
     CDS             1710..1988
                     /locus_tag="VYP30_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808556.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVARDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKSVILHFTSAKKYAKVRKTDVKEMKWL"
     gene            2274..3827
                     /locus_tag="VYP30_001586"
     CDS             2274..3827
                     /locus_tag="VYP30_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1808557.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEEKAALEKAASEEMDKAV
                     AAVQQAYLAYQQATDKAAKDAADKMIDEAKIAELEYEVQRLEKEIKEIDESDSEDYLK
                     EGLRAPLQSELDTKKAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGEQAEQYLV
                     AAEKDLDAKKTELEKTEADLKKVANEPETPAPAPKPETPAPAPEAPAPAPEAPAPAPA
                     PKPEQPAPAPKPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPAPAPKPEQPA
                     PAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNANGSMATGWVKDGDTWYYLE
                     ASGVMKASQWFKVSDKWYYVNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWY
                     YLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGY
                     EVNANGEWV"
     gene            4228..5349
                     /gene="mnmA"
                     /locus_tag="VYP30_001587"
     CDS             4228..5349
                     /gene="mnmA"
                     /locus_tag="VYP30_001587"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1808558.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            5490..5945
                     /locus_tag="VYP30_001588"
     CDS             5490..5945
                     /locus_tag="VYP30_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1808559.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKSQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            5955..7868
                     /gene="mnmG"
                     /locus_tag="VYP30_001589"
     CDS             5955..7868
                     /gene="mnmG"
                     /locus_tag="VYP30_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1808560.1"
                     /translation="MIYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKAVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(8063..9742)
                     /locus_tag="VYP30_001590"
     CDS             complement(8063..9742)
                     /locus_tag="VYP30_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1808561.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(9744..9977)
                     /locus_tag="VYP30_001591"
     CDS             complement(9744..9977)
                     /locus_tag="VYP30_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1808562.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            complement(10795..10947)
                     /gene="cibB"
                     /locus_tag="VYP30_001592"
     CDS             complement(10795..10947)
                     /gene="cibB"
                     /locus_tag="VYP30_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1808563.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYAIGKDLRK
                     KFGKSC"
     gene            complement(10949..11134)
                     /gene="cibA"
                     /locus_tag="VYP30_001593"
     CDS             complement(10949..11134)
                     /gene="cibA"
                     /locus_tag="VYP30_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1808564.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            11312..11995
                     /gene="tsaB"
                     /locus_tag="VYP30_001594"
     CDS             11312..11995
                     /gene="tsaB"
                     /locus_tag="VYP30_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1808565.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEYLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            11992..12429
                     /gene="rimI"
                     /locus_tag="VYP30_001595"
     CDS             11992..12429
                     /gene="rimI"
                     /locus_tag="VYP30_001595"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1808566.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            12419..13429
                     /gene="tsaD"
                     /locus_tag="VYP30_001596"
     CDS             12419..13429
                     /gene="tsaD"
                     /locus_tag="VYP30_001596"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1808567.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(13469..14775)
                     /locus_tag="VYP30_001597"
                     /pseudo
     CDS             complement(13469..14775)
                     /locus_tag="VYP30_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(15108..15402)
                     /locus_tag="VYP30_001598"
                     /pseudo
     CDS             complement(15108..15402)
                     /locus_tag="VYP30_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15509..15802)
                     /locus_tag="VYP30_001599"
                     /pseudo
     CDS             complement(15509..15802)
                     /locus_tag="VYP30_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            16070..17253
                     /locus_tag="VYP30_001600"
                     /pseudo
     CDS             16070..17253
                     /locus_tag="VYP30_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
BASE COUNT         5233 a         3144 c         3852 g         5024 t
ORIGIN      
        1 ctccttggat aaaatattta gagatttcta gttttatatt aactatattt ccatctattc
       61 tttatggtac agttgataat catgtactga ctcttatctt tttgataaaa atttgtgtag
      121 ataccacgat aaaattttta ttcatcagat tatttgacac aagtacttta atgaagagga
      181 gaatattttt tcttttcgca ttggatgtta tagcttactt atttttagga tatcttttag
      241 tgattcaaaa agcaggctat ttgttttcgg ttttacttct tttttctaat ttttcagttc
      301 catttatcaa agaaaaggaa tacgaattat ttaaaaatag caagtaatag aaacataggt
      361 taaatcttag aacggcttaa aatcagatat gataaaggga aatagtctta tctaggtaac
      421 taagtgctac aaacacagtc gaggatcact tgttaggatt acattttaat catgcttaat
      481 aagaatggag aattcctatg gggattgtat tactctgaag tttcgaatac cttagttctc
      541 gtgattttga gctattctag ctttagaatc cttcagaatg taaaatttta agcagtcaaa
      601 gacttagaat agcctgaaaa catttatttt atagcgattc taagcttaga attgattgga
      661 tatatatgta tttgagctgc tcgatagtta ggacagctct attctgagaa atctgagcta
      721 tcaatgcttc agaatagtat ttcgccaatg gtttttattg aagaggtgat tgttttatga
      781 tagtctaaaa taaaactgat ttaatggagt aaatggagaa tcgttacatg aaacattttt
      841 ttgtaggaat tggtgagata aaacttgttg gctacttatt gtatatatgt gtaggactag
      901 cccctctttt tcatatatat gtcataggtt cggaactgag ttttgtgaaa atagtgttat
      961 ctattttggg agttatattt gtaagtatgt taactattgc tcgaatttat aggacttttt
     1021 tctataaaga atagtttgga cttgaactgt atctaaaaac agaggttggt cgattatcag
     1081 cctctttctt gtcgttgaaa agagtgagat atattgactt ttgaaaaaaa gatgtcataa
     1141 ttgagttggg ataaacctaa aagtaatata gtagattgaa tctggaatag tccgttatga
     1201 ctgttaaaat atttctagaa attaatttga ctttcctaat cgatttgttc acatcttgtt
     1261 tcaatctact atactttctc gttaaaccgt tcggcaattc atggtgacat ggacacatag
     1321 tagtaagcac actatgtggc ttggcagagc taaaaactgt tcccttgcga taagcctaat
     1381 aagcataaca tagggagtta gagaagccga ctctaatcaa ccactttggg cagtagtgag
     1441 aactgccccg tgctttttta ttttgagaaa atatggagtt tgtcgttgaa attacttgat
     1501 tgtattttgg actatcaaga aagattcaat ggaaaaacat gtcaagtatc aacgaattat
     1561 aagtatttag agattttcaa agtgaatttt tgcttgactg atttacatca tttatttgac
     1621 ttatacaaaa tcacacgaga ttatgctagt caaacaaaac ctgctattca agctggtgtt
     1681 tttattttag aagattttag aaatatccta tgtacaatga tgtaatcgaa aggatatctt
     1741 tatatgagtt tatcggtgat attttctatt ctaaaataat aagttgttgc atcgtagcta
     1801 gggatttatc taaaaatact atgaaattgg acgtcatatt ttttgaggat aaaaataaaa
     1861 gatccgcagt tttaggttta cgaagagaca aaagcggagt atttaaatca gttattctac
     1921 attttacaag cgctaagaaa tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat
     1981 ggctataaag attgtccgca ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa
     2041 aacaagctct ctcatcggaa atgtttttat aggaatgaag gaagatgatg ctatgtttaa
     2101 aaagagaatc gaaaagggca aaagtagtgt ctttatcttt ttggagtaga agcttatgat
     2161 atagaaattt gtaataaaaa tgtaatataa aacatttgac aaatatttac ggggggagta
     2221 tacttaatat aagtatagtc taaaaatgac tatcagaaaa gaggtaaatt tagatgaata
     2281 agaaaaaaat gattttaaca agtctagcca gcgtcgctat cttaggggct ggttttgttg
     2341 cgtctcagcc tactgttgta agagcagaag aagctcccgt agccagtcag tctaaagctg
     2401 agaaagacta tgatgcagcg aagaaagatg ctaagaatgc gaaaaaagca gtagaagatg
     2461 ctcaaaaggc tttagatgat gcaaaagctg ctcagaaaaa atatgacgag gatcagaaga
     2521 aaactgagga gaaagccgcg ctagaaaaag cagcgtctga agagatggat aaggcagtgg
     2581 cagcagttca acaagcgtat ctagcctatc aacaagctac agacaaagcc gcaaaagacg
     2641 cagcagataa gatgatagat gaagctaaaa tcgctgagtt ggaatatgaa gttcagagac
     2701 tagaaaaaga gatcaaagag attgatgagt ctgactcaga agattatctt aaagaaggcc
     2761 tccgtgctcc tcttcaatct gaattggata ccaaaaaagc taaactatca aaacttgaag
     2821 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     2881 aagatttcaa aaactcagac ggtgagcaag ctgaacaata tcttgttgca gctgaaaaag
     2941 acttagatgc taaaaaaact gaattagaaa aaactgaagc ggaccttaag aaagtagcta
     3001 atgagccaga aactccagcc ccagctccta aaccagaaac tccagcccca gctccagaag
     3061 ctccggctcc agctccagaa gctccggctc cagctcctgc accaaaacca gagcaaccag
     3121 ctccagcacc aaaaccagag aagtcagcag atcaacaagc tgaagaagac tatgctcgta
     3181 gatcagaaga agaatataac cgcttgactc aacagcaacc gccaaaagca gaaaaaccag
     3241 ctccagctcc tgcaccaaaa ccagagcaac cagctcccgc accaaaaacg ggctggaaac
     3301 aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggctaca ggttggctac
     3361 aaaacaacgg ttcatggtac tacctcaacg ctaacggttc aatggcaaca ggttgggtga
     3421 aagatggaga tacctggtac tatcttgaag catcaggtgt tatgaaagca agccaatggt
     3481 tcaaagtatc agataaatgg tactatgtca acagcaatgg cgctatggcg acaggatggc
     3541 tccaatacaa tggttcatgg tactacctca acgctaacgg tgctatggca acaggttggg
     3601 ctaaagtcaa cggttcatgg tactacctca acgctaacgg ttcaatggca acaggttggg
     3661 tgaaagatgg agatacctgg tactatcttg aagcatcagg tgctatgaaa gcaagccaat
     3721 ggttcaaagt atcagataaa tggtactatg tcaatggctt aggtgccctt gcagtcaaca
     3781 caactgtaga tggctatgaa gtcaatgcca atggtgaatg ggtttaagcc gattaaatta
     3841 aatcatgtta agaacatttg acattttaat tttgaaacaa agataaggtt cgattgaata
     3901 gatttatgtt cgtattcttt aggtacctgt cttatgattt caggaaatgt cattaaaaaa
     3961 acgactcctt ttctctaact tgaaaaatag attagagaaa atgggttgtt ttatttatta
     4021 tagttatttg aatgaagata agaagaaggt atactcacat cattcacata atctgtatgt
     4081 tgactataag tttaaaaaaa caatttttaa gctcttcctt gtcttctcca accaagcgtg
     4141 ttataatgaa tactgctcaa gcgaccttca atcgtgaagc acacacgacc ttcaatcgtg
     4201 aataaacgaa tagatgggag acttaccatg agtgataact ctaaaacacg tgttgtcgtg
     4261 gggatgagtg gtggtgttga ttcgtcggtg acggctcttt tgctcaagga gcagggctac
     4321 gatgtgatcg gtatcttcat gaagaactgg gatgacacag atgaaaacgg cgtctgtacg
     4381 gcgaccgaag attacaagga tgtggttgcg gtggcagacc agattggcat tccctactac
     4441 tctgtcaatt ttgaaaaaga gtactgggac cgcgtttttg agtatttcct agcggaatac
     4501 cgtgcagggc gcacgccaaa tccggacgtt atgtgcaaca aggaaatcaa gttcaaggcc
     4561 tttttggact atgccatgac cttgggggca gactatgtag cgactgggca ttatgctcga
     4621 gtggcgcgtg atgaggacgg cactgttcac atgcttcgtg gcgtggacaa tggcaaggac
     4681 cagacctatt tcctcagcca actttcgcaa gaacaactcc aaaaaaccat gttccctctg
     4741 ggacatttgg aaaagcctga agtacgcaga ctagcagaag aagcaggcct ttcgactgct
     4801 aagaagaaag actcgacagg gatttgcttt atcggagaaa agaactttaa aaactttctc
     4861 agcaactacc tgccagctca gcctggtcgc atgatgactg tggatggtcg cgatatgggc
     4921 gagcatgcag gtcttatgta ctatacaatc ggtcagcgtg gcggactcgg tatcggtggg
     4981 caacacggcg gtgacaatgc cccttggttc gttgtcggaa aagatctaag caagaatatt
     5041 ctctatgtag gacaaggatt ctaccatgat tcgctcatgt caactagcct agaagccagt
     5101 caagtccact ttactcgtga aatgccagaa gagtttacgc tagaatgtac ggctaaattc
     5161 cgttaccgtc agcctgactc taaggtgacc gtccatgtca aaggagacaa ggcagaggtc
     5221 atctttgcgg aaccacaacg cgcgattaca ccaggacagg cagttgtctt ttacgatggc
     5281 gaagagtgtc taggtggtgg tttgattgac aatgcttacc gcgatggaca agtttgtcag
     5341 tacatttaga ttgacaaatt ttctcaattt gctacaataa taacagcaat agaaatgatg
     5401 gtcaaagctc atggatgttg caggcttttt tgtcctgcac ttctttgtag ttttgactgt
     5461 ttttgtgtcg tttaagggaa aggacaagaa tgactcaaca agactttcgg acaaaagtag
     5521 acaatacggt ttttggtgtt cgggcgacag ccttgattgt ccaaaatcac aagcttctag
     5581 ttaccaaaga caagggcaag tattacacta ttggaggtgc gattcaagtt aacgaaaaaa
     5641 cggaagacgc ggtagtccgt gaagtgaggg aagaactggg tgttaaagct caagctgggc
     5701 agctagcttt tgtggttgaa aatcgttttg aagtggacgg cgtttcctat cacaatatcg
     5761 agtttcatta tctggtggat ttgcttgaag atgccccgtt gaccatgcag gaagatgaga
     5821 aaagtcagcc ctgtgagtgg attgacttgg ataagcttga ggatatccag ctagttccag
     5881 cctttttaaa aacagcccta ccagattggg aaggccaact aagacacatt catcttgagg
     5941 aataggagag aaacatgatt tatcatttta ctgaagaata cgatattatt gtaattggtg
     6001 cgggacacgc tggggttgag gcttccttgg ccgctagccg tatgggctgt aaggtcctgc
     6061 ttgcgaccat caatattgaa atgctggctt tcatgccttg taatccctct atcggtggtt
     6121 ctgccaaggg gattgtcgta cgtgaagtcg atgccctcgg tggcgagatg gccaagacta
     6181 ttgacaagac ttacatccag atgaagatgc tcaacacagg gaaggggcca gctgtccgtg
     6241 ctcttcgtgc gcaggctgac aaggaacttt actctaagga gatgcgcaag acagttgaaa
     6301 atcaagaaaa tctgaccctt cgtcaaacca tgattgatga gattttggtg gaagatggca
     6361 aggctgtcgg tgtgcgtaca gccacccatc aagaatatgc tgctaaggct gttattgtga
     6421 cgacagggac tgctctccgt ggggaaatta tcatcggaga cctcaagtac tcatcaggtc
     6481 ctaaccacag cttggcttct attaacctag ctgacaatct caaggaactg ggtctcgaaa
     6541 tcggtcgttt caagacagga acccctccac gtgtcaaggc ttcttctatc aattacgatg
     6601 tgacagaaat tcagccagga gacgaagtgc ctaatcattt ctcatacact tcacgtgatg
     6661 aggattatgt caaggaccaa gtaccatgct ggttgaccta taccaatggt accagtcatg
     6721 agattatcca aaacaacctc caccgtgcgc ctatgtttac aggtgtggtc aagggagtgg
     6781 gacctcgtta ctgtccatcg attgaggaca agattgtgcg ctttgcggac aaggaacgtc
     6841 accaactctt ccttgagcca gaaggacgca atacagagga agtctatgtt caaggacttt
     6901 caaccagtct gcctgaggat gtccaacgtg acttggttca ttccatcaaa ggtctggaaa
     6961 atgcagagat gatgcgaaca ggttatgcta ttgagtatga tatggtcttg cctcatcagt
     7021 tgcgtgcgac tttggaaacc aagaaaatct caggtctctt cactgctggt cagacaaatg
     7081 gaacgtcagg ttacgaagag gcagcaggcc aagggattat cgcgggtatc aatgcggctc
     7141 tgaaaatcca aggcaagcct gaattgattc taaaacgaag tgacggttac attggggtca
     7201 tgatcgacga cttggtgacc aagggaacca ttgaacctta ccgtctcttg accagtcgtg
     7261 ctgaatatcg tctcattctt cgccatgaca atgctgatat gcgcttgact gagatgggcc
     7321 gtgagattgg ccttgtggac gatgaacgct gggctcgttt tgaaatcaag aaaaatcaat
     7381 ttgataatga gatgaagcgt ctagacagta tcaaactcaa gccagtcaag gaaaccaatg
     7441 ctaaggttga ggaaatgggc ttcaagccgt tgacagatgc ggtgacagcc aaggaattcc
     7501 ttcgccgtcc agaagtttct taccaagatg tggtggcctt catcggacca gctgcagagg
     7561 aattagatga caagattatc gaattgattg aaacagaaat caagtacgaa ggttacatct
     7621 caaaagccat ggatcaggtt gctaagatga agcgcatgga agaaaaacgt attccagcca
     7681 atatcgactg ggatgacatt gattctatcg caaccgaagc ccgtcagaag ttcaaactca
     7741 tcaatccaga aaccatcggc caagccagcc gtatttcggg agtaaaccca gcagatattt
     7801 ctattttgat ggtgtatctg gaaggtaaaa atcgtagtat ttctaaaact cttcaaaaat
     7861 caaaatgata cgtcgtaggc ttcttacgaa tgagttcaaa gcttggcttt gattcatctc
     7921 caacctccca tagttccccg aactatggga gctaactcaa gttatgcatt ttcctagcct
     7981 tctggtctga ttttcattga gttttaatct caaaagaaag catagagaaa aacagctccg
     8041 aagacggggc tgttttgttg ctttattctt catctggtgt gaggatcatc gggatgatga
     8101 tcggttcacg ttcggtattt tcatagagga aggggcgaat agcgttgaca atggcaccat
     8161 tgacagattg cacgctagca tccttatttt tcagtgcgat acgaatggca ttgaagagga
     8221 tacgctggct ttggcgaatc aagtctccag actctctcat gtagacaaag cctcggctga
     8281 ggatatctgg gccagacaga atcatctgcg atttgaagtc aacagttgcg actgccagaa
     8341 cgacaccgtc ttcagataga tcgcgacgat ctttgaggac agctgcgcca atttcaccga
     8401 tacgatttcc atcgacatag atatcttggg cgttgaaatg acctgcgata cgagctgagt
     8461 cagcagtaag ggcaagcaca tcgccattgc tcatgataaa gatattgtcc ttctcaacac
     8521 cagtatccac tgctagtcca gcgtggactt tttgcatgcg gtattcaccg tggacaggca
     8581 tgaagtattt tggcttaatc aagcagagca tgagtttttg ctcttgctga ccaccgtgtc
     8641 cagatgtatg gatattgttc actttaccgt ggataacttc gacaccagct tcagaaatga
     8701 tgttaatcag cttgttgacg ctagtagtgt ttccagggat gggactagaa gagaagataa
     8761 cggtatcacc tggttgtaat tgtacttgac ggtgggttcc gttggcgata cgagagaggg
     8821 ctgccatagg ctcaccctga ctacctgtac agaggataag aacttctcct gcaggataat
     8881 ctttgatttc atttggctcg ataaaggttc ccttaggagc tttgatgtag ccaagatcga
     8941 ttccgttgac aatggccttt tccatagaac gaccaaagac cgcaatcttg cgtccagtct
     9001 taacagcagc ttctgttgcc tgctggagac ggaagatatt tgaggcaaag gatgcaaaga
     9061 tgatacgtcc ttcaatacct tggataatct tcataatgga ctgaccaacg actttttcag
     9121 agttggtaaa ggttggtact tccgcatttg tcgagtcaga caggagacag agcacgcctt
     9181 cttcaccaag cgcagccata cgatgcaagt ccgcaggttc tccaactgga gtaaagtcga
     9241 acttaaagtc acccgtacag acgattttcc cttgaggagt atgaatgaca atccccaaag
     9301 gctctggaat agagtgagtc gttctaaaga aagttgcctt gagattttta aaggtcaact
     9361 cggtgttgtg gttgatttcg taaagtttgg cgttgcgcaa gaggccgtgt tcttcgagtt
     9421 tcccacggat caaagccaag gcaagcggtc cagcataaat agggacattt gcttgcttga
     9481 gtaggaacgg aatcccacca atgtggtcct cgtgtccgtg tgtgattaaa acagccttga
     9541 cgcggtcgat attgtctacg atgtaagagt agtcaggaat gacatagtcg ataccaagca
     9601 agtcatcttc tgggaattta atcccagcat cgacgatgat aatctcgtct tggtattcaa
     9661 ttccgtaagt gtttttcccg atttctccta gaccaccgat ggcaaaaaca ccaacttctt
     9721 caggtttaag agtgtaggcc atattagaac tccgtaattt cgaaggcgcc agtttctttt
     9781 tcgtaatcga gcaatttgtc agacaagagt tcgatatatt cgatattgta ctctgggcga
     9841 ttttcttcga caagttggcg agcagtgata cggccctcaa gttctgagct ggtatcgatg
     9901 tctaggtaaa gcgcgcgtgt tgtttcacgg cgtgggctac gttcttttgt ttcttgataa
     9961 aaaactttgt aaatcatata gttcctttct atttacaggt cagcttattc caaactttta
    10021 gcagatattt gcttgatttc attccatttt gtgtctagat tgaccttgat tcgttacaat
    10081 tatttcaatt ataccacaaa atgaaaaatt agtaaaagac ggaaacgaga aagttagggg
    10141 acgatttctt tggtgagcgt ttgcaaaaat aaagaaaatg tattatgttg ataacggaag
    10201 tgaaatttat tgcttgtcat aattccatat agattttaag tcaaggaggt tgccctatgt
    10261 ataacttatt tgcttttgct atcggagttc gtttgttagc ttttatcgtt tttgttgctt
    10321 gcgtttatgg aggaaatctt ctatttgcca aactggaacg atgacaaatc aagttcttga
    10381 ggaaaattac ctttgtgact ctctactcgc tttttctcct cctcgtgacc tatgtcgttt
    10441 ggtttgtatt ttactttgga ttaaatgctt agatgccctg cttatgctgg ggttttttgt
    10501 ttggggatgt agagatagta gatttacgac acgaaaattc caccccatct atcaagatga
    10561 ggtggtcttt gcatttttct aaaatgacat gacaatggaa ttttcaaagc ttattatttt
    10621 tatgggagtc attgttctgc tcaaaaatag agttgaagca taaaaataaa acaatacaaa
    10681 cagataaatc gaatggtaaa gggatagtag taatgttcaa atcattgaga atgctgagca
    10741 aactgtaaga gatgaagaca ataaaattta tccttctaaa aatgtgtttc ttatctagca
    10801 tgatttacca aactttttac gaaggtcttt tccaatggca taacctgcca taaataaagc
    10861 gataccaaca cctacaccaa agccaccctt gatttcttgc aattccttat tagaaatttc
    10921 acgatagttg ttcaaatttt tcatcatatt aatctcctcc taaaaaataa ccagctgcca
    10981 aaccagaacc tataagtgct gttccacctg caatagcttt ccaagatact gctactccaa
    11041 agataaccaa gggagcgaga ccgccatcaa tatctgataa ttcattttca gataaggata
    11101 aaaattgatt gtcaagaatg tcaaaatttg tcattgaact ttcctccttt tttcttgttc
    11161 acttttatat tcggaaaaga aaaggaaaag tgagcatttt tttaaattat ttttagttaa
    11221 gtgagggcac tcttgtctgg gggcaaagaa aattcccatg tgccagcttt tgtagtataa
    11281 tagtaagcag acaaaaagat aggaatgtgt tatgaaagta ttagcttttg atacgtccag
    11341 caaggctctt tctctcgcta ttttagagga caagcagatt cttgccgaga tgacgattaa
    11401 tattaagaaa aatcacagta ttaccctcat gcctgccatc gattttttga tggcaagttt
    11461 ggactggaca cccaaggatt tggaccgaat cgtggtggct gaagggccag gtagctacac
    11521 aggcttgcga attgcggtag ccactgccaa gactttggct catactctga acatcgagtt
    11581 agttggtatg tctagcctct tggctctggt accctaccaa caagaaggct tgtttgtctc
    11641 cttgatggat gcgcgtcgca acaatgttta tgcaggattt tatgaaaatg ctaaacctgt
    11701 catgccagaa gcgcacctat cttttgaaga ggtgctagaa aaagtcaagg gtgctagtca
    11761 ggtaaccttt gtcggagaag ttggcccctt tgttgagcag attcaagaat acttgccaag
    11821 gactaattat aaagaaacct tgcctaatgc agccaatctt gctcttttag cttgggacaa
    11881 ggaagcagac tccttgcatg attttgtgcc gaattacctc aaacgagtcg aggctgagga
    11941 aaactggctc aagaaccata ccgagtctgg cgagtcttac attaaacgcc tatgatagaa
    12001 atcaagcgaa ttcaacaaca gcctgaccta gctcaagcca tctacgctgt tatggcagct
    12061 gtttacctag tcagtccttg gactctggag caaatccaag cagatctgtc ccaagaccag
    12121 acttggtatg cattggctta tgatggggca gaagtgattg gatttctagc tgtgcaggag
    12181 aatctttttg aagcagaagt cctgcaaatc gctgtcaaag gagcttatca gggtcaggga
    12241 attgcgtcag ccttgtttgc tcaattgccg acagacaagg aaattttcct cgaagtcaga
    12301 cagtcaaatc aacgagcgca agcattttac aagaaagaaa agatggcagt tatcgctgag
    12361 cgaaaggcct actaccatga cccagtcgag gacgccatta tcatgaagag agaaatagat
    12421 gaaggataga tatattttag catttgagac atcctgtgat gagaccagtg tcgccgtctt
    12481 gaaaaacgac gatgagctct tgtccaatgt cattgctagt caaattgaga gtcacaaacg
    12541 ttttggtggc gtagtgcccg aagtagccag tcgtcaccat gtcgaggtca ttacagcctg
    12601 tatcgaggag gcattggcag aagcagggat taccgaagag gacgtgacag ctgttgcggt
    12661 tacctacgga ccaggcttgg tcggagcctt gctagttggt ttgtcagctg ccaaggcctt
    12721 tgcttgggct cacggacttc cactgattcc tgttaatcac atggctgggc acctcatggc
    12781 agctcagagt gtggagcctt tggagtttcc cttgctagcc cttttagtca gtggtgggca
    12841 cacagagttg gtctatgttt ctgaggctgg cgattacaag attgttgggg agacacgaga
    12901 cgatgcagtt ggggaggctt atgacaaggt cggtcgtgtc atgggcttga cctatcctgc
    12961 aggtcgtgag attgacgagc tggctcatca ggggcaggat atttatgatt tcccccgtgc
    13021 catgattaag gaagataatc tggagttctc cttctcaggt ttgaaatctg cctttatcaa
    13081 tcttcatcac aatgccgagc aaaagggaga aagcctgtct acagaagatt tgtgtgcttc
    13141 cttccaagca gcagttatgg acattctcat ggcaaaaacc aagaaggctt tggagaaata
    13201 tcctgttaaa accctagttg tggcaggtgg tgtggcagcc aataaaggtc tcagagaacg
    13261 cctagcagcc gaaatcacag atgtcaaggt tatcatcccc cctctgcgac tctgcggaga
    13321 caatgcaggt atgattgcct atgccagcgt cagcgagtgg aacaaagaaa actttgcaaa
    13381 cttggacctc aatgccaaac caagtcttgc ctttgatacc atggaataaa gagtggctct
    13441 ttgtcaagtg tagtgggtag gcgaaaagct acaatctgga gagtacgaaa ttcgtactct
    13501 cttttttgat gttcaaagtc atcaaaatcc gttttttaaa attgttaaag ttccggaaac
    13561 caaaggcttt gcacttgata accttaatca aattattggt cgcttcaagt ttagcgttgg
    13621 aataaggcag cttaagtgcg ttgataatct tatctctatc ccttaaaaaa gtccaaaaga
    13681 ccgtttgaaa aagcggatga accgttggca gttcttgctc aatcaatcca aagaaatggt
    13741 cggcattctt ctcttgaaaa tgaaagagca ggagttgata gagttcgtag taaacctgta
    13801 atccctcaga gtaagaaagc agcttatctc gtacttcccg atgggttaag tgcattcgaa
    13861 acgtgggctg atagaatcgt ttctgacaga gcttgaagct atcctggtgt agtaaatcag
    13921 tccagtggac tgatttagcc cgagcctaga aacgaaaaag cgagggttcc aaaagcgctt
    13981 gagcgcccga tactccaagg attttcggtc aaattggttc atgatttgga ttcgtactcg
    14041 gttcatagct cggctcagat gttggacaat gtggaagcgg tcaagaacaa tcttcgcctt
    14101 tggaaagagt tgcttagcga gccgataata agggctgtac atgtccatgg tgatgacctc
    14161 gaccagctcc cgaacctctc tctgatagcg ttggaaatgg tttcgaatca ccgcatgagt
    14221 tcgcccgtct aaaattgcga ggatggattt ggactcaaaa tcttgggcaa tgaagctcat
    14281 tttgctcttt ttgaagctat actcatccca actcataact tttggcaact tggtccaatc
    14341 ggtttcaaac ttaaattccc tcagttttcg gatgatggtg gaagttgaga ccgccaatct
    14401 gtgggcaatc tcagtcatag actgcttttc aaggaggagc tgagcgattt tttgtctcac
    14461 catgttggaa atctggcaat ttttcttgac aatggatgtt tgagaaacga ccaccttaag
    14521 gcaattcttg cactgaaagc ggcgcttttt gagatgcagt accgtgggta aaccctgaca
    14581 gtcgagaagc ggaattttag aggctttctg gaagtcgtat ttgatcatct tcccttgaca
    14641 atgaggacaa ggaggagcgg gggaatccaa ctttgcctga acgactagat gggtttggta
    14701 tttcagaaca gacaagattt tgatattttt gtcttccaat ccgagcaaat ctgtggtatt
    14761 cttaagttgt tccatatgaa ccctttctaa tgagttggtt agacgctttt cattataggt
    14821 catatggggc tttttttcta caagaaacga ccctataatt cctggggtgg gattacccac
    14881 tacagaaatt atagagccaa aacattccaa agtcttgtct gactctggaa tgttttctgt
    14941 tcacagttgt tttgtaactg cctaataagt aaccgcgcta taacgaggta tctaccgaga
    15001 ttgtcaattc tccagtatac tgttataaaa aacaaaactg gaggattttt ttatgtcccc
    15061 ccatcgtccc atcgactgtt ccgtagctgc ccaataacgg agtataatca gatgaaacaa
    15121 gaataggaca aaagtgcctc aagaaaagca tcgtaatttg acaatattat tctgagatgt
    15181 ttttgatgta agcccatatt ttctcaatgg gattatactc gggtgaatag gtaggaagtg
    15241 gtaacagtct atgccctgct ccttacacat gttcattctg tgaaaccttg cattgtccat
    15301 aatgataagg gatggtgtat ctaaagtagg tagtaagaat ttttggaagc aagcttcgaa
    15361 aaagtcactc gtcatcgtat ctttataggt catcggagcc atagtatatt gaaacaaaaa
    15421 agggcattag tacttctata acagtatcgc aatctctggt gtgcgttgtc tcgatcttaa
    15481 ttcaaataat tatatcttct tccagagaga ctaactgcct gctcaaggct cgatcatatt
    15541 cgagataaaa ataagtctca acccctgtct cataaatata aataggagtc aggtagctta
    15601 agtgattcaa ttctttaagg aaccgattta ctttttctgg gtcttgttcg cagtaggtac
    15661 ggctcttttt tagactatat cccatagcct ttagagcgta atgaatagtt gttggaggac
    15721 agttgaattc agcagctatt tcagtcaaat aagcatcggg atgagtttca atatagatct
    15781 ttaatttatc tctatcaact ttttcaatta atagtggaag ttttcttaaa gttagtgtgt
    15841 tgaaacgttt ttatacagtg ctaaaatttg aagtgtagtg cagatgtatt tgtaatagta
    15901 ttatagcaat tctttggaga aggtcgagac aagagaaaat aggtatcttt gagatataag
    15961 catgatttac tataaaatta ttgagttatt cataaaaatt tctctatcaa atatcataat
    16021 gcgtcgttta aggagatggt tacaatgcaa tattaaggag atggttacaa tgcaatatag
    16081 ttgtggaaaa ataaatatta atatccctga tggatatgga gacattaagg atatagtgtt
    16141 ttcggctcat attatagtta ggtataataa tggacattgt ggaggtatag atccgcatat
    16201 aattggactt tgtaaaaagc agatcagaag gatgtctcta tatcctattt tgataatcgt
    16261 atctagagat tcaaaggtta ttgatgatta taaaaattta gatattgcct atgttgattg
    16321 tactcaatgt tcaaataatt ttgaaactgc cttacacgtt aaaaatattt taaaattatt
    16381 aaaaatccga cttatacact gtcatggcta ctcaactaat tattttttat atatgttaaa
    16441 aaaacttgac aagaatggat ttggaaaggt taagacagtg ataacatgcc atggatgggt
    16501 tgaatataac ttaaaaaaga aattcttgac ttattttgat ttttggacat attctatggg
    16561 agatgctttt atttgtgtat ctgaaactat gaaaaaaaga ttggagagta taataaaaaa
    16621 ataagaagat agttgcaata aataacggaa ttaatgtatc aaatagcgat ttagatgtag
    16681 taggtgttca agactttaaa aaagaatttt gtattccaaa taacaaaaaa atcatttgtt
    16741 atgttggaag gttggatcca gaaaaaaggc cggatagatt ccttgaattt gcagaaaaat
    16801 tatttttagt cagagaagat gtgattttta ttatggctgg aaatggtagt atgtgggctg
    16861 ctttgaaaga aaaaatttgc catttgaaat gtagagataa tttcaggtta cttggtgaaa
    16921 tctatccagc tactatagtt taccaaatat cggatttatt gtatattcct tatgatacag
    16981 aaggaatacc tatgtgtgtt ttagagtcaa tgtcacaagg aactccggtt ttagctagta
    17041 atgttggcgg gttaagtgaa attattgaac atagggttga tggattttta tttgagaagg
    17101 aagatgttga gggagtgtgt gcttgtgcta attttttact caatgattct gagtatttga
    17161 aatatatagg tgagaatagt aaatcaaaaa taagaaaaca tttttctgtg caaaaaatgt
    17221 ttgtagaaac catgagagta tatgatgaat tat
//
LOCUS       DAVMBH010000042        16876 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVMBH010000042 DAVMBH010000000
VERSION     DAVMBH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16876
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.042"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            817..1038
                     /locus_tag="VYP30_001601"
     CDS             817..1038
                     /locus_tag="VYP30_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808568.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1555..1794
                     /locus_tag="VYP30_001602"
                     /pseudo
     CDS             1555..1794
                     /locus_tag="VYP30_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1938..3167
                     /locus_tag="VYP30_001603"
     CDS             1938..3167
                     /locus_tag="VYP30_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1808569.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3187..5883
                     /gene="ppc"
                     /locus_tag="VYP30_001604"
     CDS             3187..5883
                     /gene="ppc"
                     /locus_tag="VYP30_001604"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1808570.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5966..6183
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6296..7300
                     /locus_tag="VYP30_001605"
     CDS             6296..7300
                     /locus_tag="VYP30_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1808571.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7369..8235
                     /locus_tag="VYP30_001606"
     CDS             7369..8235
                     /locus_tag="VYP30_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808572.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8232..8990
                     /locus_tag="VYP30_001607"
     CDS             8232..8990
                     /locus_tag="VYP30_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808573.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9080..10840
                     /gene="dnaG"
                     /locus_tag="VYP30_001608"
     CDS             9080..10840
                     /gene="dnaG"
                     /locus_tag="VYP30_001608"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1808574.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10843..11952
                     /gene="rpoD"
                     /locus_tag="VYP30_001609"
     CDS             10843..11952
                     /gene="rpoD"
                     /locus_tag="VYP30_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1808575.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11966..12295
                     /locus_tag="VYP30_001610"
     CDS             11966..12295
                     /locus_tag="VYP30_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1808576.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12410..13453
                     /gene="cpoA"
                     /locus_tag="VYP30_001611"
     CDS             12410..13453
                     /gene="cpoA"
                     /locus_tag="VYP30_001611"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1808577.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13469..14794
                     /locus_tag="VYP30_001612"
     CDS             13469..14794
                     /locus_tag="VYP30_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1808578.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14825..15001
                     /locus_tag="VYP30_001613"
     CDS             14825..15001
                     /locus_tag="VYP30_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1808579.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15060..15194
                     /locus_tag="VYP30_001614"
     CDS             15060..15194
                     /locus_tag="VYP30_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1808580.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15258..16568
                     /gene="obgE"
                     /locus_tag="VYP30_001615"
     CDS             15258..16568
                     /gene="obgE"
                     /locus_tag="VYP30_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1808581.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            16578..16736
                     /locus_tag="VYP30_001616"
     CDS             16578..16736
                     /locus_tag="VYP30_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808582.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         5195 a         2933 c         3706 g         5042 t
ORIGIN      
        1 tttattttta cctatagcta tctttatgca aatttgctgt ataagatttg attccatttt
       61 agcaaaggcc ttacctaata ttttgctgat acttattgtt ttaatcacgt ttcagagtga
      121 ttggaatata tttatacctg caacttatta ttatacagaa attcagtcaa ctacaaactt
      181 aggtattaaa ttattagttt gtatctggat tatgggattt gaattttccc ttcttccaaa
      241 actaataaaa ttgaaagaac aaaatctagt ttaaatgttg ctcgaaaatt aaataattga
      301 atacgattaa caatgaaaca atacaacgtg agtcatgact tcaaagtaat tgattttatg
      361 attctggttt cttacgctta attaagcaag ttgtattcac tttatcaaat tgttattact
      421 ctaaaaagcg tctaacagct atagagtgtc tgtttgcttc tctttacttt tattttaaat
      481 aattcattaa ccttccgtaa gtgcccaata ataaggtgtg ttgaagaagt ctgagataaa
      541 atagttctca gtcacaaaaa aagctataga ttcccattgg tgaacagctc cctgtcaagt
      601 agacagtaaa ataatataaa atcttaagcg acctgattcc tgaattccag tggagtcagg
      661 ttgtttttta accgtctttc ttaatattgt ctcacctata atagatatgc ttatgagata
      721 tgtttaataa attaatttta gttcaaaatg tccagttagg acactttgaa tgatttctta
      781 gttttatata ttatactttt ctcaggagaa agctagatgt acagacgttt gagagatttg
      841 agggaagatc acgatttgac ccaaaaacaa atagctaaaa tactttcgtt tacaaactca
      901 gcttatgcta aaattgaacg gggtgagcat acgttaacag cagatgtatt ggtaactctc
      961 tcaaactttt acgatgtcag tacagactac ctattggaat tgacagattt tcctgataaa
     1021 attcgcttta gaaaataatc tcctcaattt catagagtgt gaaaatgagg agatttttta
     1081 tttgttcttt gaaaattaaa tagtccaaaa tggtactttc ctcatttgtg gagcaaattt
     1141 gaatggctcg ccatgataag agcgatttta aaaccatcaa taaaatagag cgatacttta
     1201 tatgccatga tacaaatgat atacaatgat acttctgacc gttcaggctg ccatcgtaaa
     1261 agagcagcaa gtgaaattct tatgatgact tcatcagtca tgccacgttg aatgtgtgag
     1321 tttgttagag aaacgcaatt aatcctcaaa aggttccccg aaccttttga gttccacaga
     1381 cgcatcacgt ggagtgtgta agcttgttgc taaaagcgta aaaaccttgg aacgaaagga
     1441 ataatagact tcctgcgaaa caaaaataca atacaataaa actatggatg atgaagcaag
     1501 taaacaatta agcgatagcc gtttcaagag ccttgtaggt gttcagcgca cgagatgtta
     1561 gctgtgttaa aaacagctta tcaacgcaac gtaaacgcgc aaaaggtgga cgaaaaacca
     1621 aattaagcct agacgatctc ctcatggtaa ctattcaata catgcgagaa tagcgcactt
     1681 atgaacaaat tgcggctgat tttggcattc acgaaagcaa cataattagt cggaggtcaa
     1741 tggattgaag caactcttat tcaaaatggt tttacgattt caaattctgc cttaattctg
     1801 taaaaacagt aaaattcgaa ggattgtaag gtaagagttt ttttctttct gaaaaaatgg
     1861 tataatagca atcaaaacta gaaaataaaa cggaatttgg aacagatttg tctgtatcct
     1921 agtagagtgg tgatactatg aagattagta agaggcactt attaaattat tccatcttga
     1981 ttccctactt gcttttatct attttgggct tgattgtggt ctattcgacc accagtgcta
     2041 ttttaattga agaaggcaag agcgccttgc agttggttcg aaaccaagga atcttttgga
     2101 ttgttagttt gatactgatt gccttaattt ataaattgag actagatttt ttgagaaatg
     2161 agcgactaat cattttagtt atattaatag aaatgctttt attgttcttg gctcgtttta
     2221 ttggtatttc agtaaacggg gcatacggtt ggatttcggt tgcaggagta actattcagc
     2281 cagctgagta cttaaaaatc attattattt ggtatttagc tcaccgattc tccaaacagc
     2341 aagaagaaat agctacttat gattttcaag ttttgactca aaatcaatgg cttccccgtg
     2401 cttttaatga ttggcgattc gttctcctag ttctgattgg aagtttggga attttccctg
     2461 atttaggaaa tgcgactatt ttagtcttgg tttccttgat tatgtataca gttagtggaa
     2521 tcgcttatcg ctggttttca accattctgg cgctcgtatc tgccgcttct gtctttgtct
     2581 tgaccactat cagcctaatc ggtgttgaga ccttttcaaa aattccagta tttggctatg
     2641 tagccaaacg ctttagtgcc ttttttaatc cttttgccga tcgtgctgat gcaggtcacc
     2701 agttagctaa ttcttatttt gccatggtca atggtggttg gtttggtcta ggtcttggaa
     2761 actcgattga aaaacgaggt tatttgccag aagctcatac agactttgtc ttttctatcg
     2821 tgattgaaga atttggcttt gttggtgcca gtcttatttt agctctcttg tttttcatga
     2881 ttttgcggat tatcttggtc ggtattcgag cggagaatcc tttcaatgcc atggttgcac
     2941 tcggtgtcgg agggatgatg ttggttcagg tatttgtcaa tatcggaggg atttcgggct
     3001 tgattccatc tacaggagta accttcccct tcttatccca gggtggaaat agtcttctag
     3061 tcttatcagt ggcagtagcc tttgtcttaa atattgatgc cagtgaaaaa cgcgctaagt
     3121 tgtaccgaga attggaaaat caaccaatga accttctgtt gaagtaggat aaagaaagga
     3181 tagtttatgt ctcttcaaaa attagaaaat tctagtaata aaagtgttgt gcaagaagaa
     3241 gtcttgattc taacagaatt actggaagat attactaaaa atatgcttgc cccagagacc
     3301 tttgaaaaaa taatacagtt gaaagaatta tcaacgcagg aagattatca aggtctaaac
     3361 cgtctagtga ctagcttatc aaatgatgaa atggtctata tttcacgcta tttctctatc
     3421 ttgcctcttt tgattaatat ttcagaggat gtggatttag cttatgaaat caatcatcaa
     3481 aataatattg atcaggacta tttaggtaaa ttatctacaa cgattaaatt ggtagcagaa
     3541 aaggaaaatg ccgttgagat cctagaacac ttgaatgttg ttccggtttt gacagcccat
     3601 ccaacacaag tgcaacgcaa aagtatgttg gatttaacaa atcatattca tagtcttttg
     3661 cgtaaatacc gtgatgttaa gttggggttg atcaataaag ataaatggta caatgatttg
     3721 cgtcgttaca tcgaaattat catgcagaca gacatgattc gtgagaaaaa attaaaagtg
     3781 actaacgaaa tcacgaatgc tatggaatat tataacagct cctttttgaa agctgtacct
     3841 catttgacga cggagtataa gcgcttagcg caagcgcatg gtctgaattt aaaacaggct
     3901 aaaccaatca ccatgggtat gtggataggt ggtgaccgtg atggaaatcc atttgttaca
     3961 gcaaagacct tgaagcagtc tgcactcact cagtgtgaag tcatcatgaa ctactatgat
     4021 aaaaagattt accaacttta tcgtgaattt tctctttcaa ctagcattgt caacgtcagc
     4081 aaacaagtca gagaaatggc tcgtcaatcc aaggataact cgatttaccg cgaaaaagag
     4141 ctttaccgtc gtgccttgtt tgatattcaa tcaaaaattc aggcaactaa aacctatctg
     4201 attgaggatg aagaagttgg gactcgttat gaaaccgcca atgatttcta caaggatttg
     4261 attgccattc gagattctct actagaaaat aagggcgagt ccttgatttc aggtgatttt
     4321 gtggaattat tgcaggcagt agagatattt ggtttttact tagcatcaat tgatatgcga
     4381 caagactcta gcgtctatga agcctgtgtg gcagaactct tgaaatcagc aggaattcat
     4441 tctcgttata gcgagttgag cgaagaagaa aagtgtgacc ttctcttgaa agaattagaa
     4501 gaagatcccc gaattctttc tgcgactcac gcagaaaaat cagaattatt agcaaaagaa
     4561 ctagctattt ttaagacggc tcgtgttttg aaagataagt tgggagatga tgtcatccgt
     4621 cagaccatca tttcacatgc aaccagcctt tctgatatgc tagaattagc tattctgtta
     4681 aaagaagtag gactggtgga tacggaaagg gcgcgtgttc agattgttcc cctttttgaa
     4741 acaattgaag acttggatca ttcagaggaa acaatgagaa aatatctttc tcttagcctt
     4801 gccaaaaaat ggattgactc acgaaataac taccaagaaa tcatgcttgg ctactctgac
     4861 agtaataaag atggcggtta cttgtcatca tgttggaccc tctacaaggc tcaacaacaa
     4921 ttgactgcta ttggagatga atttggcgtt aaggttacct tcttccatgg tcgtggtggt
     4981 actgtcggtc gtggtggtgg gccaacctat gaagccatta catctcaacc gctcaagtct
     5041 atcaaggatc gtatccgctt gacggagcag ggtgaagtaa ttgggaataa atacggtaac
     5101 aaagacgccg cttactataa ccttgaaatg ctagtatcgg cagctattaa ccgtatgatt
     5161 actcagaaga agagcgatac caatacccca aatcgttatg aagccattat ggatcaagta
     5221 gtggaccgta gttacgatat ctaccgtgat ttggtctttg gtaatgagca tttctatgat
     5281 tatttcttcg agtcaagtcc aatcaaggct atttcaagtt ttaatattgg ttctcgtcca
     5341 gccgctcgta agactattac tgaaatcggt ggattgcgtg ctatcccttg ggtattctca
     5401 tggtcacaga gtcgtgttat gttccctgga tggtacgggg ttggttcaag cttcaaggaa
     5461 tttatcaata aaaatccaga gaatattgct atcttacgag atatgtacca aaattggcct
     5521 ttcttccaat cgcttctttc aaatgttgat atggttttgt caaaatcaaa tatgaatatt
     5581 gcttttgaat atgctaaact ttgtgaagac gagcaagtta aggccatcta tgagactatt
     5641 ttaaatgaat ggcaagttac taagaacgtt atcttggcta ttgaaggaca tgacgaactc
     5701 ttagctgaca atccatatct aaaagctagt ctggattacc gtatgcctta ctttaatatt
     5761 ctcaactata ttcagttaga gttgattaaa cgccaacgtc gtggagaatt gtccagtgat
     5821 caagaacgat tgattcatat caccatcaac ggaattgcga caggattgcg taattcaggt
     5881 tgataatttt caagagtgaa tgctaaaagt gaatatcaaa aaaattctaa tagactattg
     5941 acaagtagtt taaaaatgat ataatttaac cattcagaaa agtaatcata caaacttttt
     6001 agagagtctg tggtagctga aaacagataa gtggcaatga tgaaaattgg gctgaatgct
     6061 atttagaatt tgaaattata aaaattcggt aagcacacct tacagtgcat ctcgttattg
     6121 cgagactgag cgatagggaa attccctata attgaggtgg taccgcgcat cgacgtcctc
     6181 acacaagttt tttgtgtgag gatttttttg atggaggtta gtatggaaag aaaacgatgg
     6241 cgtcgcttgt ttagataagt gaaatatgtt aaaggaaata aaaaggagaa acagaatgaa
     6301 aaataaacgt ttaattggaa ttattgctgc attagcagtc ttagtagcag gaagcttgat
     6361 ttattcttca atgaataaat cagaagctca gaataataag gatgagaaga aaataaccaa
     6421 gattggtgtg cttcaatttg tgagccatcc atcccttgat ttgatttata aagggatcca
     6481 agatggactt gcagaagaag gatataaaga tgatcaagtt aaaattgatt ttatgaactc
     6541 agaaggtgac caaagtaagg ttgcgacaat gagtaaacaa ttggttgcaa atggaaatga
     6601 ccttgtggtt ggtatcgcaa caccagcagc ccaagggttg gctagtgcaa caaaagacct
     6661 accggttatc atggccgcta ttacagaccc aattggtgct aacttggtta aagatttgaa
     6721 aaaaccaggt ggcaacatta caggggtatc tgaccacaat ccagctcaac aacaagttga
     6781 actcatcaag gctctgacac cgaatgtgaa aacaatcgga gctctttact caagtagcga
     6841 agacaattca aaaacacagg tcgaagaatt taaggcttat gctgaaaaag caggtctgac
     6901 agtggaaaca tttgcagttc cttcaacaaa tgaaattgcc tcaactgtca ctgttatgac
     6961 tagcaaggta gatgctattt gggttccaat tgataacacc attgcatcag gatttccaac
     7021 ggttgtctct agcaatcaaa gttctaagaa accaatttat cccagtgcga cagctatggt
     7081 agaagtaggt ggtttggcat cagttgtaat tgaccaacat gaccttggtg tggcaacagg
     7141 taaaatgatt gtgcaagtct tgaaaggtgc aaaaccagcc gataccccag tcaatgtctt
     7201 ttcaactggt aagtcagtca tcaataaaaa aatagcacaa gaactaggta ttactattcc
     7261 tgagtctgtt ctcaaagaag caggacaagt catcgaataa ataaggtagg gaggaggaga
     7321 ctcttcccat tttttaaaaa gatgaatata gaaaggatta aataaaatat gattgtttcc
     7381 attatttctc aaggatttgt ctgggctatt ctaggtctgg gaatctttat gacatttagg
     7441 attttaaact ttccagatat gacgacagaa ggttccttcc ctcttggggg agctgttgct
     7501 gtcactttga taaccaaagg cgtgaaccca tttttagcga cacttgttgc tgtaggagca
     7561 ggttgtttgg ctggaatggc agcaggcctt ctttatacaa aagggaagat cccaaccttg
     7621 ctctcaggga ttttggtgat gacttcttgt cactcaatca tgctcttgat tatgggacgt
     7681 gcgaatttag gcctgcttgg aaccaagcaa attcaggatg ttttgccttt tgattcggat
     7741 ttgaatcaac tcttgacagg tctcatcttt gtgagtattg ttattgctct catgctcttt
     7801 ttcttggaca ctaaactcgg acaagcctat attgctacag gggataatcc tgatatggct
     7861 agaagtttcg ggattcatac tggacgcatg gagctcatgg gcttggtctt atcaaatggt
     7921 gtgattgccc ttgcaggtgc cctcattgct cagcaagaag gctatgccga tgtgtctcga
     7981 gggatcgggg ttatcgttgt ggggcttgca agtttgatta ttggagaagt tattttcaag
     8041 agtttgagct tggcagagcg tttggttact atcgttgtag gttctatcgc ttatcaattt
     8101 ttagtgtggg cagttatcgc acttggcttt aatacaagtt accttcgttt atacagtgcc
     8161 ttgattttag cagtctgcct catgattcca acatttaagc aaacaatctt gaaaggagcc
     8221 aagttaagca aatgacagca attgtagaat taaaaaatgc aaccaaaatc gttaaaaatg
     8281 gctttgatga agaaaagatt attttaaatg atgtttcctt agaaattttt gaacgggact
     8341 ttatcacgat tttgggcgga aatggtgctg gaaaatcaac cctctttaac actatagcag
     8401 ggaccttatc actaactagt ggaactatcc gtattttagg tgaagaactc actaagtttt
     8461 cacccgagaa gcgtgccaag tacctgtctc gtgtcttcca agatccaaag atggggacag
     8521 ctccccgtat gacggtcgct gaaaatcttt taatcgccaa gtttcgtggt gaaaagcgtg
     8581 gattgttacc acgacgcttg actagctata aggatgaatt tcaggcaacc attgaaaaag
     8641 taggaaatgg tcttgagaaa cacttgaata caccgattga gttcttatca ggtggacaaa
     8701 gacaggcttt gagtctcttg atggcaacct tgaagcgacc tgaattactc ctgttagatg
     8761 agcatactgc tgccctggat ccaaagacta gtgttgcttt gatggaattg acagatgaat
     8821 ttgttaagaa agatcagcta acagccctta tgattactca tcatatggaa gatgctctca
     8881 aatacggcaa tcgcttgatt gtcatgaaag aaggacggat tatccaagat ttaaaccaag
     8941 aagaaaaagc aaaaatgaaa atctctgatt attatcaact ctttgaataa agtagggaaa
     9001 atgagtgaaa tggtttactt tttttctgaa ataaagtata ctatataaag taaactatga
     9061 taacatggag gtattgtgta tggttgacaa acaagtcatt gaagaaatca aaaacaatgc
     9121 caacattgtg gaagtcatag gagatgtgat ttctttacaa aaggcaggac ggaactatct
     9181 agggctctgt ccttttcatg gtgaaaaaac accttctttc aacgttgtag aggacaagca
     9241 gttttaccac tgttttggtt gtggtcgctc aggtgatgtc tttaaattca tcgaggagta
     9301 ccaaggggtt acctttatgg aggctgtcca aatcttaggt cagcgtgtcg ggattgaggt
     9361 tgaaaaaccg ctttatagtg aacagaagcc agcctcgcct caccaagctc tttatgatat
     9421 gcacgaagat gcggctaaat tttaccatgc tattctcatg acaacgacta tgggcgaaga
     9481 ggccagaaat tacctttatc agcggggttt gacagatgaa gtgcttaaac atttttggat
     9541 tggtttagca cctccagaac gaaactatct ctatcaacgt ttgtctgatc agtatcgtga
     9601 agaagattta ctggattcag gcctgtttta tctctcggat gccaatcaat ttgtagacac
     9661 ctttcacaat cgcattatgt ttcccctgac aaatgaccaa ggaaaggtca ttgccttctc
     9721 aggtcgtatc tggcaaaaaa cagattcaca aacttctaag tataaaaaca gccgatcgac
     9781 tgcaattttt aacaaaagtt acgaattata tcatatggat agggcaaaaa aatcttctgg
     9841 aaaaactagt gagatttacc tgatggaagg attcatggat gttattgcag cctatcgggc
     9901 tggaatcgaa aatgctgtgg cgtcgatggg aacggccttg agtcgagagc atgttgagca
     9961 tctgaaaagg ttaaccaaga aattggttct tgtttacgat ggagataagg ctgggcaagc
    10021 cgcgatattg aaagcattgg atgaaattgg tgatatgcct gtgcaaatcg ttagcatgcc
    10081 tgataacttg gatcctgatg agtatctaca aaaaaatggt ccagaagact tggcctatct
    10141 attaacgaaa actcgtatta gtccgattga gttctacatt catcagtaca aacctgaaaa
    10201 cagtgaaaat ctgcaggctc agattgagtt tattgaaaaa atagctccct tgattgttca
    10261 agaaaagtcc atcgctgctc aaaacagcta tattcatatt ttagctgaca gtctggcgtc
    10321 ctttgattat gcccagattg agcagattgt taatgagagt cgtcaggtgc aaaggcagaa
    10381 tcgcatggaa ggaatttcca gaccgacgcc aatcaccatg cctatcacca agcagttatc
    10441 ggctattatg agggcagaag cccatctact ctatcggatg atggaatccc ctcttgtttt
    10501 gaacgattac cgtttgcgag aagactttgc atttgctaca cctgaatttc aggtcttata
    10561 tgacttgctt ggccagtatg gaaatcttcc tccagaagtt ttagcagagc agacagagga
    10621 agttgaaaga gcttggtacc aagttttagc tcaggatttg cctgctgaga tatcgccgca
    10681 ggaacttagt gaagtagaga tgactcgaaa caaggctctc ttgaatcagg acaatatgag
    10741 aatcaaaaag aaggtgcagg aagctagcca tgtaggagat acagatacag ccctagaaga
    10801 attggaacgt ttaatttccc aaaagagaag aatggagtaa taatggcaac aaaacaaaaa
    10861 gaagtaacaa catttgacgt acaggtagca gaatttatcc gtaatcataa gcaaaaaggg
    10921 acagcaacag atgatgaaat caatgcaagt ctggttattc cttttacctt ggacgctgat
    10981 gggattgaag atctcttgca acggattcag gatgcaggca tttctatcac agataacgaa
    11041 ggaaatccaa gtgcgcgtgt tcttagcaat gaagaagaac cagaactcag cgatgaggac
    11101 ttgattgggt caacttctgc taaggtcaat gaccctgtcc gtatgtactt gaaagaaata
    11161 ggggtcgttc ctctcttgac caatgaagag gagaaagagt tggcactggc tgttgaagct
    11221 ggcgatatcg aagccaaaca acgtcttgcg gaagccaatc ttcgtttggt tgtttctatt
    11281 gccaaacgct atgtcggtcg tggcatgcag ttccttgact tgattcaaga aggaaatatg
    11341 ggcttgatga aggcggttga caagtttgac tattctaaag ggttcaagtt ttcaacttat
    11401 gcaacttggt ggattcgtca ggctatcact cgtgctattg cggatcaagc tcgtaccatc
    11461 cgtatcccag ttcacatggt tgaaactatc aataaattgg ttcgtgaaca gcggaatctc
    11521 cttcaagaat tggggcaaga tccgacacca gaacagattg ctgaacgaat ggatatgaca
    11581 cctgataagg ttcgtgaaat cttgaagatt gcccaagaac cagtatctct tgaaactcct
    11641 atcggtgaag aggacgatag ccaccttgga gactttatcg aagatgaagt gattgaaaat
    11701 ccagtggatt atacgactcg tatcgtcttg cgtgagcaat tggatgaaat cttagatact
    11761 cttacagacc gtgaagaaaa tgttctgcgt ctacgttttg gactagatga tggaaaaatg
    11821 cgcacacttg aagatgtggg gaaagtcttt aacgtaactc gtgagcgtat ccgtcagatt
    11881 gaagcaaagg ctttgagaaa actacgccaa ccaagccgca gcaaaccgct tcgtgatttt
    11941 attgaagact aagagtgagg aaaatatggc ttatacagaa gagcaaattg aaaacatcaa
    12001 aacacggatt ttaacagcct tggaagaagt catcgaccct gagttgggaa tcgatattgt
    12061 caatcttggt ttgatctatg agattcgttt tgacggtgac acagggcaaa cagagattga
    12121 catgactttg acaactatgg gttgtccctt agcagacctt ttgacagacc agatttatga
    12181 tgctatgata gaggttccag aagtaacgga tactgaggtt aaattagtct ggtatccagc
    12241 ctggacagtt gaaaaaatga gtcgctatgc ccgcattgcc ctaggcatta agtaaacata
    12301 taaaagcatg tgagagactg ttggaaaagc gaggaaattt cccctctttt cctctagtct
    12361 ctcctttctt ttgctgattt tattcaaaga aaatgatata atagtagtta tggagaaaaa
    12421 gaaattacgc atcaatatgt tgagttcaag tgagaaagta gcaggacagg gagtttcagg
    12481 tgcttaccgt gaattagttc gtcttcttca ccgtgctgcc aaggaccaat tgattgttac
    12541 agaaaatctt ccaatcgagg cagatgtgac tcactttcat acgattgatt ttccctatta
    12601 tttatcaacc ttccaaaaga aacgctcagg gagaaagatt ggctatgtgc atttcttgcc
    12661 agctacactt gaaggaagtt tgaaaattcc atttttctta aagggaattg tgaaacgcta
    12721 tgtattttct ttttacaacc ggatggagca cttggttgtg gtcaatccta tgtttattga
    12781 ggatttggta gcagctggta ttccacgtga aaaagtgacc tatattccta actttgtcaa
    12841 caaggaaaaa tggcatcctc taccacaaga agaggtagtc agactgcgca cagatcttgg
    12901 tcttagtgac aatcagttta tcgtagtagg tgctgggcaa gttcagaaac gtaaagggat
    12961 tgatgacttt atccgtctgg ctgaggaatt gcctcagatt acctttatct gggctggtgg
    13021 cttctctttt ggtggtatga cagatggtta tgaacactat aagaaaatta tggaaaatcc
    13081 ccctaaaaat ttgatttttc caggcattgt atcgccagag cggatgcgcg aattgtatgc
    13141 tctagcggat cttttcttgt tgcctagtta caatgagctc tttcctatga ctattttaga
    13201 agctgcgagt tgtgaggctc ctattatgtt gcgtgattta gatctctata aggtgatttt
    13261 ggagggaaat tatcgggcga cagcgggtag agaagagatg aaagaggcta ttttggaata
    13321 tcaagcaaat cctgctgtct taaaagatct caaagaaaag gctaagaata tttccagaga
    13381 gtattctgaa gagcatctgt tacaaatctg gttggacttt tatgagaaac aagccgcttt
    13441 agggagaaag taaaaagtga ggtaatctat gcgaattggt ttatttacag atacctattt
    13501 tcctcaggtt tctggtgttg cgaccagtat tcgaaccttg aaaacagaac ttgaaaagca
    13561 gggacatgct gtttttatct ttacgacgac agataaggat gtcaatcgct acgaagattg
    13621 gcaaattatc cgcattccaa gtgttccttt ctttgctttt aaggatcgtc gctttgccta
    13681 ccgaggtttt agcaaggcac ttgaaattgc taaacagtat cagctagata ttatccatac
    13741 tcagacagaa ttttctcttg gcctgttggg gatttggatt gcgcgtgaat tgaaaattcc
    13801 agtcatccat acctatcaca cccagtatga agactatgtc cattatattg ctaaggggat
    13861 attgatccgg cctagtatgg tcaagtatct ggttagaggt ttcctgcatg atgtggatgg
    13921 ggttatttgc cctagtgaga ttgtccgtga cttgctatct gattataagg tcaaggttga
    13981 aaaacgggtc attcctactg ggattgaatt agccaagttt gagcgtccgg aaatcaagca
    14041 ggaaaatttg aaagaactgc gtagtaaact agggattcaa gatggtgaaa agacgttgct
    14101 tagtctttcg agaatctcct atgaaaaaaa tattcaagca gttttagcag cctttgctga
    14161 tgttctgaaa gaggaagaca aggttaaact ggtagtagct ggggatggcc cttatctgaa
    14221 tgacctcaaa gagcaagccc agaacctaga gattcaagac tcagtcatct ttacagggat
    14281 gattgctcct agtgagacgg ctctttacta taaagcggcg gatttcttca tttcggcatc
    14341 gacaagcgaa acgcaaggtt tgacctactt ggaaagctta gccagtggaa cacctgtcat
    14401 tgctcacgga aatccttatt tgaacaacct catcagtgat aaaatgtttg gagccttgta
    14461 ctatggagaa catgatttgg ctggtgctat tttggaagcc ctgattgcaa caccagacat
    14521 gaacgagcat accttatcag agaaattgta tgagatttca gctgagaact ttgggaaacg
    14581 agtgcatgag ttttatctgg atgccattat ttcaaataac ttccagaaag atttggctaa
    14641 agatgatacg gtcagtcagc gtatctttag gacagttttg tatcttccgc aacaggtggt
    14701 tgctgtacct gtaaaaggat ctagacgcat gttgaaggct tcaaaaacac agttgatcag
    14761 tatgagagac tattggaaag accatgaaga atagaaagag gaacagctat gaaaaaaaca
    14821 attaatgaga agcggtcgtg ataaaaagat tgcgggtgtt tgtgctgggg tggcccatta
    14881 tctggatatg gatccgacta tcgttcaagt catttggggt gttcttactt gctgttacgg
    14941 agctggaatt gtagcttaca ttattttatg gattatcgca ccagtagcaa ctgactattg
    15001 aaaactagct caattcatgc taagataata gaaaatagaa tgtaacgaag gagagaaaaa
    15061 tggcatttgg agataatgga aatcgtaaaa aaactatgtt tgagaaaata accttgttta
    15121 tcgtgattat catgctagta gcaagtttat tgggaatttt tgcaactgca attggtgccc
    15181 tcagtaatct ataaaataga ttcaagaaaa tttagtgact gggatttccc agcccttttt
    15241 taaagtgaga agaaataatg agtatgtttt tagatacagc taagattaag gtcaaggctg
    15301 gtaatggtgg cgatggtatg gttgcctttc gtcgtgaaaa atatgtccct aatggaggcc
    15361 cttggggtgg tgatggtggt cgtggaggca atgtggtctt cgttgtagac gaaggactac
    15421 gtaccttgat ggatttccgc tacaatcgtc atttcaaggc tgattctggt gaaaaaggga
    15481 tgaccaaagg gatgcatggt cgtggtgctg aggaccttag agttcgagta ccacaaggta
    15541 cgactgttcg tgatgcggag actggcaagg ttttaacaga tttgattgaa catgggcaag
    15601 aatttatcgt tgcccacggt ggtcgtggtg gacgtggaaa tattcgtttc gcgacaccaa
    15661 aaaatcctgc accggaaatc tctgaaaatg gagaaccagg tcaggaacgt gagttacaat
    15721 tggaactaaa aatcttggca gatgtcggtt tagtaggatt cccatctgta gggaagtcaa
    15781 cacttttaag tgttattacc tcagctaagc ctaaaattgg tgcctaccac tttaccacta
    15841 ttgtaccaaa tttaggtatg gttcgcaccc aatcaggtga atcctttgca gtagccgact
    15901 tgccaggttt gattgaaggg gctagtcaag gtgttggttt gggaactcag ttcctccgtc
    15961 acatcgagcg tacacgtgtt atccttcaca tcattgatat gtcagctagc gaaggccgtg
    16021 atccatatga ggattaccta gctatcaata aagagctgga gtcttacaat cttcgcctca
    16081 tggagcgtcc acagattatt gtagctaata agatggacat gcctgagagt caggaaaatc
    16141 ttgaagaatt taagaaaaaa ttggctgaaa attatgatga atttgaagag ttaccagcta
    16201 tcttcccaat ttctggattg accaagcaag gtctggcaac acttttagat gctacagctg
    16261 aattgttaga caagacacca gaatttttgc tctacgacga gtccgatatg gaagaagaag
    16321 cttactatgg atttgacgaa gaagaaaaag cctttgaaat tagtcgtgat gacgatgcga
    16381 catgggtact ttctggtgaa aaactcatga aactctttaa tatgaccaac tttgatcgtg
    16441 atgaatctgt catgaaattt gcccgtcagc ttcgtggtat gggggttgat gaagcccttc
    16501 gtgcgcgtgg agctaaagat ggggatttgg tccgcattgg taaatttgag tttgaatttg
    16561 tagactagga gactggtatg ggagataaac cgatatcttt ccgagatgcg gatggtaatt
    16621 ttgtttccgc cgcagacgtt tggaatgaaa agaaattgga agaactattt aatcggctca
    16681 atccaaatcg tgccttgaga ttggcacgaa ctaaaaagga aaatccatct cagtaaagaa
    16741 gctaaaaaat ccggctcttt gtcaactgta gtaggttgaa gaaaagctaa gcttgagaaa
    16801 ggacaaattt cgtcctttct tttttgatgt tcagagcgat aaaaatccgt tttttgaagt
    16861 tttcaaagtt tcgaaa
//
LOCUS       DAVMBH010000043        16188 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVMBH010000043 DAVMBH010000000
VERSION     DAVMBH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.043"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            198..293
                     /locus_tag="VYP30_001617"
                     /pseudo
     CDS             198..293
                     /locus_tag="VYP30_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VYP30_001618"
     CDS             complement(546..1166)
                     /locus_tag="VYP30_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1808583.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VYP30_001619"
     CDS             complement(1166..1648)
                     /locus_tag="VYP30_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1808584.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VYP30_001620"
     CDS             complement(1648..2490)
                     /locus_tag="VYP30_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1808585.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VYP30_001621"
     CDS             complement(2585..3385)
                     /locus_tag="VYP30_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1808586.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VYP30_001622"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VYP30_001622"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1808587.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDIEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VYP30_001623"
     CDS             4918..5463
                     /locus_tag="VYP30_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1808588.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VYP30_001624"
     CDS             5475..5789
                     /locus_tag="VYP30_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1808589.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VYP30_001625"
     CDS             5806..6498
                     /locus_tag="VYP30_001625"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1808590.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VYP30_001626"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VYP30_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1808591.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7164..7754
                     /locus_tag="VYP30_001627"
     CDS             7164..7754
                     /locus_tag="VYP30_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1808592.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7763..9526
                     /locus_tag="VYP30_001628"
     CDS             7763..9526
                     /locus_tag="VYP30_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1808593.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9740..10381
                     /locus_tag="VYP30_001629"
                     /pseudo
     CDS             9740..10381
                     /locus_tag="VYP30_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10548..10748
                     /locus_tag="VYP30_001630"
     CDS             10548..10748
                     /locus_tag="VYP30_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808594.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            10790..11194
                     /locus_tag="VYP30_001631"
     CDS             10790..11194
                     /locus_tag="VYP30_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808595.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            11425..12132
                     /gene="ccdA2"
                     /locus_tag="VYP30_001632"
     CDS             11425..12132
                     /gene="ccdA2"
                     /locus_tag="VYP30_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1808596.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            12143..12700
                     /gene="sdbB"
                     /locus_tag="VYP30_001633"
     CDS             12143..12700
                     /gene="sdbB"
                     /locus_tag="VYP30_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1808597.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGQEETKKTQAAQQPKQQTTVQQIS
                     VGKDVPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            13074..14465
                     /locus_tag="VYP30_001634"
     CDS             13074..14465
                     /locus_tag="VYP30_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1808598.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            14608..15525
                     /gene="adcAII"
                     /locus_tag="VYP30_001635"
     CDS             14608..15525
                     /gene="adcAII"
                     /locus_tag="VYP30_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1808599.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLAEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            15533..>16188
                     /locus_tag="VYP30_001636"
     CDS             15533..>16188
                     /locus_tag="VYP30_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1808600.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     "
BASE COUNT         5016 a         2837 c         3432 g         4903 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatcttagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgcaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactggcca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaagtctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aattccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaatttgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atagagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcctagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaagtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga acccctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agttttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 ttgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaagg tttgtcagga cacaccttgg tcattgcagg agatacccct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaacg agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatattgaga ttgctccgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg ttattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggcagtctct tacgaaattc cagccggaaa attggaggta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tagatgataa tgaggagact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaaaat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg cttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgatcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat ccgagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aaaaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtatagttg attagaacag
     7141 agacagtaga ggagaggtac agaatggaac gattagaaga ttacattgct tttgatttag
     7201 aatttaatca gcacgaagga caaacacact tgattcaagt atcggcagtg cgttttagag
     7261 atggtcggga aatcgatgcc tatgattcct atgttcatac cagcgtccct ctaaaaagct
     7321 ttatcaatgg tttgaccggg attacagctg agaccttaaa agatgctcct ccagttgaga
     7381 aagtcttaga agaattccaa gagtttgtgg gttctttgct gatgataggc tacaatgctg
     7441 ctaaaagtga tttacctatt ttagcagagc atggtttaga ctatagccaa cagtacaagg
     7501 tggatttgta tgatgaagct tttgaacgtc ggagttcaga tttacatggt attgccaatc
     7561 tcaaattgca aactgttgcc tcatttcttg gatttcaagg tcagtctcat aatagtttag
     7621 aggatgctcg gatgacggcg cgtgtttacg aatccttctt agagtcggat caagctaggg
     7681 aattgttaga gacagaaagt agcttatcaa acaatccttt tggtggcttg gacttgtctc
     7741 aattatttga ctaggagtgc ctatgaaacc tgaaaaacct aaaaaattgg gtcttaaaca
     7801 gatttacctc aatcttgata aaatcctctt tctatttttc ttgattttta tgatagtgga
     7861 gtatttgtgg gtaccattca attcatggtt ggctagcttc ttattagatc agacaggtta
     7921 tctttttatt tcctataaca atgtcttagc catccttact cattctccat tgattagtct
     7981 agctttttta gccttgattg taattaacct tctggttgct tattttcaaa taggactcct
     8041 ctttattggt gctcgtcatc tcctctataa tgaaaagcga aggctaattg agtatatccg
     8101 caaggttttc catgaaagtt ttggatttat gaaaaagcta acttgcgcta aagccttgtt
     8161 tatctttttc tatatagcta tgctttttcc ttttatacgg aaaatgttga agatttatta
     8221 tcttaataaa atcgtcattc cagagtttat ccaagcttat ttagaagata aatattggat
     8281 gtggtggctg agcatcctac ttctatctct tatctttctc tatgtctctg tcagattgat
     8341 gtttgccctt ccgaagattg tatatgatca gctgactgtt cgagaagcag tgatgtttag
     8401 cttggagaaa accaagaaga gagttacttt ttatgcttgg aatttatttt acatcttgct
     8461 caaagcacat ttattatttt atcttccttt gattccttta ttattggctc aaactttggt
     8521 agatgatatc actcagagag agtctctgat tcttggtatt ttgaattttg tcgtgattaa
     8581 aaatctctat tatatggctc tgacttattt tttggttaaa tttgtttcat ttttgacagg
     8641 aaaggagctg gatatgcttc ctaggagaga aaaagatcac atcgtgcgat ggggtgtcat
     8701 gacttgtgcc agtcttttct ttgccttaga aggttatatt tatctggagg ctcccatggt
     8761 tcatctacct caacttattt ctcaccgagg ggtttccaat gcaaatggga ttcaaaatac
     8821 agtagagtcc ttggaaacta cagcacaact caaaccagac ttggtggaga cggacgtgca
     8881 ggaaacaaaa gatgggcagt ttgtcatgat gcatgatgct aacttgaaaa atctagcagg
     8941 tatcaataaa agtcctcaag acttaaactt ggaggagctt aaagggattg atatttttga
     9001 aaatggctac cagactaaaa tttcaagctt tgaagattat ctcagtcgag ccaacgaact
     9061 tggtcaaaaa ttactaattg aaattaaaac cagtaaaaaa gatagtccag acatgatgaa
     9121 ccgcttttta gcccgttatg ctgcaaagct caagatttat ggacatcaaa tccagtcttt
     9181 agactaccat gttgtcgaaa aagtaagaca gtatgatgcc gaactgccag tttatttcat
     9241 catgccctac aattctgtct ttcctaaaac aagagcgaca ggatatacta tggagtactc
     9301 aaccttggat gaatattttg taagcaaact atggacaacg gatcagaaac tttatgtctg
     9361 gactgtcaat gattcagaag ctatcagcaa atctcttcac ttaggagtag atggagtgat
     9421 tacagatgat ttggaaaaag ttcagcggga aatagaagta gcccaagaag atccagaata
     9481 tacggatttg ctcttgaaaa aagcattgga attctttgaa ttttagtaat aaaaaagagg
     9541 aacggttgtt cctcccatga taggtaagta ttcttgtgaa tgcttgcttt tttgtggttg
     9601 caatccgttt acgagaattg tttgtattgt tcttgtttca atttacttta tagtgctttg
     9661 aagttggaat gctacactat aacttataaa atatagtaaa atgaaccaaa aatagtacac
     9721 aatgtggtat aatcttctta tggcatattc aatagatttt cgtaaaaaag ttctctctta
     9781 ttgtgagcga ataggtagta taacagaagc atcacacgtt ttccaaatct cacgtaatac
     9841 catttatggc tggttaaagc taaaagagaa aacaggagag ttaaaccacc aagtaaaagg
     9901 aacaaaacca agaaaagttg atagagatag acttaaaaac tatcttactg acaatccaga
     9961 cgcttatttg actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc
    10021 gttcaaagct atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag
    10081 aaaagtagcc ttatttctta agaattttaa tagtttaaag cacctagcac ctgtttagat
    10141 tgatgaaaca ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca
    10201 gttaagaaga ggcaaagtat ctggaagaag atatcagagg atttctttgg ttgcaggtct
    10261 aacaaatggt gaattaatcg ctccaatgac ttacgaagag atgatgacga gcgacttttt
    10321 tgaagtatgg tttcagaagt ttttcttacc aacattaacc acaccatcgg ttattatagt
    10381 aaaatgaaat aagaatagga caaatcgatc aggacagtaa aatcgaattc taacaatgtt
    10441 ttagaagtcc atatgtacta ttctagtttc aatataccat aactgttcct agtcaacctg
    10501 caagccctgt cccagctcca agctcagctc cgactcaaga tcctagagtg gtagcaagcg
    10561 cttcggctag ctcaacgagc acacaagctc aagagcaagt tgacaagtct gaacttcgtg
    10621 ccttgagtca agagttagac caacgcttga aagctttggc aacagtatct gatccgaaaa
    10681 tcgatgcaac caaggctgtc ctcctagatg ctcaaaaagc tccggaagat agtgccttga
    10741 cagagtaagg tctgcatact gcagtagagt ctgtgaaggc tgggctgcct tggactctct
    10801 caaagatgtg aaagcaaatg ctagcgacag caagcctgca caggacaaga aggatgcaaa
    10861 acaaggaacg gaagatagta aggattcaga taagatgact gaaacaaact cagttccggc
    10921 aggagtgatt gtggtcagtc tacttgccct cctaggcgtg attgccttct ggctgattcg
    10981 ccgtaagaaa gagtcagaaa tccagcaatt aagcacggaa ttgatcaagg ttctaggaca
    11041 gctagatgca gaaaaagcgg ataaaaaagt ccttgccaaa gcccaaaacc ttctccaaga
    11101 aacccttgat ttcgtgaaag aagaaaatgg ctcagcagag acagaaacta aactagtaga
    11161 ggagcttaaa gcaatccttg acaaactcaa gtaaaacatg atttatgaaa tgtcagacct
    11221 aaaagacatt ttcgttcaca aaagcagcga tgagtaatcc ttgtcgttgc tttttggcta
    11281 ttttggggga taagatccgc cttgactagc aaaagaaaag attggtccaa tagtgcccga
    11341 tacgattttg cgtagcagaa agcttacaaa taaaattgaa tatagtaaaa taggattaga
    11401 attattaaga aagttggttc tttattggaa acgatagtat ttttaatctc tgtttttcta
    11461 gcaggtgttt tatccttttt ttctccttgt atttttcctc ttctgccagt ctatgctggg
    11521 attttattgg atgatcaaga aagtgcaaaa agcttttctt tgtttgggag aaaggttctc
    11581 tggtcaggct tgattcgaac actttgcttt atcgctggta tctctctcat tttctttatt
    11641 ctaggctttg gtgctggtta ctttggtcat attctctatg caaattggtt tcgatatgtc
    11701 atgggagcta ttattatcat tttgggtctt caccagatgg aaatttttca tttgaagaaa
    11761 ttagaagttc aaaaaagttt tacctttaaa aaatcagatt ctaatcgtta ttggtcagct
    11821 tttttacttg gtattacctt tagctttggt tggacacctt gtattggtcc agttttaagt
    11881 tctgttttag cacttgcggc ttctggaggc aatggtgctt ggcaaggagc gatttatact
    11941 ctcatttaca ctctgggcat ggcccttcct ttcttggtct tggcactagc ttcaggtcta
    12001 gtcatgccat attttagtaa aatcaagcgt catatgatgc tactaaagaa aattggtggt
    12061 ttcctcattg ttttaatggg aattttgtta ctattaggac aagtaaatgt tctagctgga
    12121 atttttgaat aaaggaggac aaatgaaaaa agtaatgttt gctggcttaa gtctcttgtc
    12181 attagttgta ttgatggcct gtggtcagga agaaactaaa aagactcaag cagcacaaca
    12241 gccaaaacaa caaacgactg tacaacaaat ttctgttgga aaagatgttc cagactttac
    12301 attgcaatcc atggatggca aagaagttaa gttatctgat tttaagggta aaaaggttta
    12361 cttgaagttt tgggcttcat ggtgtggtcc atgcaagaaa agtatgccag agttgatgga
    12421 actagcggcg aaaccagatc gtgatttcga aattcttact gtcattgcac caggaattca
    12481 aggtgaaaaa actgttgagc aattcccaca atggttccaa gaacaaggat ataaggatat
    12541 cccagttctt tatgatacca aagcaaccac cttccaagct tatcaaattc gaagcattcc
    12601 tacagaatat ttaattgata gccaaggaaa gattggaaag attcaatttg gtgctatcag
    12661 taatgcggat gcagaagcag catttaaaga aatgaactag aatcgataaa atctgattac
    12721 aagatgtagt cagattttgg taacttctaa aactaacttc cagtttccca caacctagct
    12781 tttagtatga gaaaaacgcg tgacatcagt ggaaatccgt cttagactaa cttccactgg
    12841 ttttcttttt cttgatatat aagggttcaa aagcgaaaag actcagaaaa agtgcacgac
    12901 aaatagccct aaaacagagt cgtcttagag taacttccag ttttgggaga gagatggaag
    12961 ttactttgag aagttacggt agtcagattt ttttagaaaa acattttata aatattcaca
    13021 tatctcctat atttatggta aaatagaatt atcagtttat tttggagtca aagatgaata
    13081 tatttagaac aaagaatgtt agtttagata aaacagagat gcataggcat ttgaagttat
    13141 gggatttgat tttgctgggt atcggagcca tggtagggac aggcgtcttt acaatcacag
    13201 gtactgcagc tgcaacactt gctggcccag ccctagtgat ttcaatcgtt atttctgcct
    13261 tgtgtgtggg attatcagcc ctcttttttg cagaatttgc ctcgcgagta cccgctacag
    13321 gaggtgccta tagttacctc tatgctatct taggagaatt ccctgcctgg ttggctggtt
    13381 ggttaaccat gatggagttc atgacagcca tatcaggcgt agcttcgggt tgggcagctt
    13441 attttaaagg cttgctctct caatacggga tagcctttcc tcaggcttta aatggtacct
    13501 ttaatcctca agcagggaca tttgttgatt tattgcctat tcttgtcttg gtcttggtga
    13561 cttcgcttgt tttactaaat gccaaggcag ccttacgctt taattcgatt ctagttattt
    13621 tgaaattttc cgctttagct ctctttgttt tagtaggaat ttggaatatt aagtttgata
    13681 attggagcaa ttttgctcct tacggttttg gacaaatcta tggagctagt actggtatta
    13741 tggctggtgc atccttgatg ttcttcggtt ttttgggatt tgaatccatc tctatggctg
    13801 tagatgaagt caagactcct caaaaaaata ttcctagagg gattgtctta tcgctttcta
    13861 tcgtaaccat tctctatgcc ttggtgaccc ttgttttgac tggtgtggtt cactatagtc
    13921 atttaaatgt cgatgatgcc gttgcctttg cccttcgtag tgttgggatt agttgggcag
    13981 ccaactatgt gtcattagtg gctatcttga ccttgattac agtttgtatt tcgatgacct
    14041 atgccctatc gcgtatgatt tacagtttag cacgtgacgg cttagtgcct gctgccttta
    14101 aggaactgac gaagactagc aaggtaccaa agaatgctac tatcttgaca ggtctagctt
    14161 cagcagtagc agcaggaatg ttcccactag ccagtattgc agccttttta aatatttgta
    14221 ccttagccta cttgatcatg ttggcttatg gtctgattcg cttacggaaa gaaaaaggaa
    14281 tgcccaaagc tggggaattt aaaacaccat tggtacctct gttaccaatt ttatcgatca
    14341 tcatttgttt atccttcatg ttacagtata atatgaatac ctggattgct ttcctagttg
    14401 cgttgttagt aggaagtatt atttacttca cttatggcta taagcattct accatagaag
    14461 aataaagtga aagtctattg agttgttgac actcagcaga tttttatatg tgaaagaaat
    14521 ttcaaatttt ttctaaaaat atcttgacag attaaatttt caggagtaga atatttacta
    14581 gttaattaaa tggttaagga gttgttcatg aagaaacaaa atttattttt agtcctgtta
    14641 agtgtctttc ttttgtgctt gggggcttgt ggtcaaaagg aaagtcagac aggaaagggg
    14701 atgaaaattg tgaccagttt ttatcctatc tacgctatgg ttaaggaagt atctggtgac
    14761 ttgaatgatg ttcggatgat tcagtcaagt agtggtattc actcctttga accttcggca
    14821 aatgatatcg cagccatcta tgatgcagat gtctttgttt accattctca tacactcgaa
    14881 tcttgggcag gaagtctgga tcccaatcta aaaaaatcca aagtgaaggt cttagaggct
    14941 tctgagggaa tgaccttgga acgtgtccct ggactagagg atgtggaagc aggggatgga
    15001 gttgatgaaa aaacgctcta tgaccctcac acatggctag atcctgaaaa agctggagaa
    15061 gaagcccaaa ttatcgctga taaactttca gaggtggata gtgagcataa agagacttat
    15121 caaaaaaatg cgcaagcctt tatcaaaaaa gctcaggaat tgactaagaa attccaacca
    15181 aaatttgaaa aagcgactca gaaaacattt gtaacacaac atacagcctt ttcttatcta
    15241 gcgaagagat ttgggcttaa tcaacttggt attgcaggca tctctcctga acaagaacca
    15301 agtccacgac aattagcaga aattcaggaa tttgttaaaa cctataaggt taaaacgatt
    15361 tttacagaaa gtaatgcttc ttcaaaagta gctgaaactc ttgtcaaatc aacaggtgtg
    15421 ggtcttaaaa ctctgaatcc tttagagtca gacccacaaa atgacaagac ctatttagaa
    15481 aatcttgaag aaaatatgag tattctagca gaagaattaa agtgaggaaa gaatgaaaat
    15541 caataaaaaa tatctagcag gttcagtggc agtccttgcc ctaagtgttt gttcctatga
    15601 gcttggacgt taccaagctg gtcaggataa gaaagagtct aatcgagttg cttatataga
    15661 tggtgatcag gctggtcaaa aggcagaaaa cttgacacca gatgaagtca gtaagaggga
    15721 ggggatcaac gccgaacaaa tcgtcatcaa gattacggat caaggttatg tgacctctca
    15781 tggagaccat tatcattact ataatggcaa ggtcccttat gatgccatca tcagtgaaga
    15841 gctcctcatg aaagatccga attatcagtt gaaggattca gacattgtca atgaaatcaa
    15901 gggtggttat gttatcaagg tagatggaaa atactatgtt taccttaagg atgcagctca
    15961 tgcggataat attcggacaa aagaagagat taaacgtcag aagcaggaac acagtcataa
    16021 tcacgggggt ggttctaacg atcaagcagt agttgcagcc agagcccaag gacgctatac
    16081 aacggatgat ggttatatct tcaatgcatc tgatatcatc gaagatacgg gcgatgccta
    16141 tatcgttcct catggcaatc acttccacta tattcctaag agtgattt
//
LOCUS       DAVMBH010000044        15691 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVMBH010000044 DAVMBH010000000
VERSION     DAVMBH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15691
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.044"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VYP30_001637"
     CDS             complement(<1..532)
                     /gene="nusG"
                     /locus_tag="VYP30_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1808601.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
     gene            complement(587..763)
                     /gene="secE"
                     /locus_tag="VYP30_001638"
     CDS             complement(587..763)
                     /gene="secE"
                     /locus_tag="VYP30_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1808602.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VYP30_001639"
     CDS             complement(773..925)
                     /gene="rpmG"
                     /locus_tag="VYP30_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1808603.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            complement(978..3173)
                     /locus_tag="VYP30_001640"
     CDS             complement(978..3173)
                     /locus_tag="VYP30_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1808604.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGVYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKSQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            3299..4135
                     /locus_tag="VYP30_001641"
     CDS             3299..4135
                     /locus_tag="VYP30_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1808605.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTFSNTFEKELKK
                     NG"
     gene            complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VYP30_001642"
     CDS             complement(4203..5210)
                     /gene="gap"
                     /locus_tag="VYP30_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1808606.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(5387..6337)
                     /locus_tag="VYP30_001643"
     CDS             complement(5387..6337)
                     /locus_tag="VYP30_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1808607.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYNDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            complement(6423..7269)
                     /locus_tag="VYP30_001644"
                     /pseudo
     CDS             complement(6423..7269)
                     /locus_tag="VYP30_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(7399..8271)
                     /locus_tag="VYP30_001645"
     CDS             complement(7399..8271)
                     /locus_tag="VYP30_001645"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1808608.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            8508..9818
                     /locus_tag="VYP30_001646"
     CDS             8508..9818
                     /locus_tag="VYP30_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1808609.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            complement(10184..10378)
                     /locus_tag="VYP30_001647"
     CDS             complement(10184..10378)
                     /locus_tag="VYP30_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1808610.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(10838..11566)
                     /locus_tag="VYP30_001648"
     CDS             complement(10838..11566)
                     /locus_tag="VYP30_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1808611.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            11682..13134
                     /locus_tag="VYP30_001649"
                     /pseudo
     CDS             11682..13134
                     /locus_tag="VYP30_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976651.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            13152..14447
                     /locus_tag="VYP30_001650"
     CDS             13152..14447
                     /locus_tag="VYP30_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1808612.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     AMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQKMEG"
     gene            14452..14760
                     /locus_tag="VYP30_001651"
     CDS             14452..14760
                     /locus_tag="VYP30_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1808613.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            14757..15065
                     /locus_tag="VYP30_001652"
     CDS             14757..15065
                     /locus_tag="VYP30_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1808614.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEAQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         4885 a         3147 c         2741 g         4918 t
ORIGIN      
        1 attctgcgat ttggtttagg tttacttctg caactgtgtc attaccaaac atagagataa
       61 tcattttcac tttgttatta tcaatttctg taatcttacc agtgtagtct gcaaaagcac
      121 catcaataat acgtacagtt tgaccaatct caacatcgaa atcaaattct tgaacagttt
      181 gtcccataga taccaaaatg tcacgaattt cttgttccaa taatggagtt ggttttgatc
      241 tgttcccgtg tgatccgaca aatcctgtaa catttggtgt gtttcgaaca acaaaccaag
      301 cttcatctgt catgaccatt tctacaagaa cataacctgg aaagcgattt tcttctactt
      361 cttttctctt tccatttttt tcaacttgca ctgtttgtgt tggaatttca acgcgtagaa
      421 tattatccaa catattgtag gtttgtgcac gttgtaatag attttctttc accttatttt
      481 cataaccaga ataagtttgt aaaacaaacc atcctttatc aaaactatcc atgatatttc
      541 ctttcataaa tagaagattt ctagtgtaat taactccact aatcttctaa aaaatgttaa
      601 taaatcgaat caaacctgaa acaatcaact ggtcaaaaat gtaaataatt actacaaaga
      661 aagctgtgta ttccatgata gaacgaaaat ctctccagct ttccttgcga gttggccatg
      721 ttgtgtcttt aagaagtcta aaaatatctc caataaaacg catcgctctc tcctatctcg
      781 tttctctgtg tgtagtgtac ttgccacaat gcttacaaaa tttatttact tctagtcgtg
      841 taggcttggg gtttccgctg atcttgattg aatagtttct cgaaccacaa accgcacaag
      901 ctaggcttgc tttttttagt gccataacgc ctccatctta tccattataa caagaaagct
      961 aggctttgac aagcatctta acgaaataga ttgactatcg aatcccatat tgtttgagcc
     1021 ttttccttaa tcttcgcatc tgagatagcc cggctagcct catctactag actttgcgca
     1081 cgccctcgaa tatcagacaa attatcatct gtctggctat tatcattggt ttgtacttgt
     1141 ctttttgtat tggctggtgc aattccattt tgcttataag cattttcaac cgtaaaggta
     1201 cttcctggcg tataaggtaa aatggtattg gcaatgtttc taaagacatg agctgcaccg
     1261 tttgaagtag agccagctag atagtgattt tcatcagtgg taggaaagcc aagccagtgg
     1321 ctaatcacta catccggagt ataaccaatt acccactggt cacttgtgta ctccggattg
     1381 aaaactgctt cagttgttcc agttttccct gccataatat agtctgcagg cgatgaacta
     1441 ataccggtac cgttggtgaa agtccccaac atcatactgg tcatcttgtc agctacagac
     1501 ttatcaatca cccgtttttg tgaattttta tgactcgcaa taacttgtcc actagcattt
     1561 tcaattctac taataaaatg agcttcaggc attaaacctt catttgcaaa ggcagcgtat
     1621 gcttgagcca tttgaagagg gttggtttca acaccgcttc ccaaggcgac accaagaaca
     1681 cggtcgacct tttccatgtt gagtccgaat ttttcgcctg cctcaaaagc cttgtcgaca
     1741 cccaaatcat taacagtggc aacagcaggt agattaagcg attctgccaa ggcttgatac
     1801 ataggaactt ctcgactcgt tttgatccct gcatagttat caaccttata gctgtcatac
     1861 tgcatggtat ggttatccaa ctgcttattc aaagcccagc ctgcttcaac tgctggcgta
     1921 taaacaacta aaggcttaat tgtagaacca ggactacgct ttgattgggt tgcatagttg
     1981 aaattccgga atccagtttt atcattgtca gcaacttgac cgacaactcc acgaactccc
     2041 cctgttttcg gttcgagagc tacacttcct gattgagcaa acgttccatc ctctgccctc
     2101 ggaaatagcg atgtgttttc ataaacaatc tgcatatttg cttggtagtt ttggtccagc
     2161 tctgtgtaaa tgcggtagcc attattgaca atctcttcct ctgttagatt atacttggaa
     2221 acagcttcat taaccaccgc atcaaaataa gaggggtaac ggtaatctga gatttttcct
     2281 tcatacttat cgtgcaattg cgaagtcata tcaacttcag cagcttcggt ttcttggctt
     2341 ttatcaatat atcctgctgc aaccatattc tgcaagacag tatcgcgccg attagtagaa
     2401 tcttctacag aattcaaggg attatacagt tccggcccct tgagcatccc tgccagagtc
     2461 gcagcttgat ccagactcac ttctgatgca gaaactccaa agtatttctt actcgcatct
     2521 tctacacccc acacaccatt tccaaaataa gcgttgttaa ggtacatggt tagaatttgc
     2581 tccttactat attttttgct taattctaag gcaaggaaaa attctttcgc ttttctctca
     2641 acagtttgat cctgcgataa ataggcgttt ttagccagct gttgggtaat ggtagagcca
     2701 ccacctgaac gtccagcagt gacaatagcc aagaagaaac ggccatagtt aatcccgtca
     2761 tttttataga aagaacggtc ttctgtcgca ataacagcat tctgcaagtt tttactgatg
     2821 tcagtcagct caacataggt tcccttttga ccagacaagg caccagcctc tttttcttca
     2881 cggtcaaaaa taagagtccg agttttcaag gcattttgca aatcattgac attggtcgac
     2941 ttggctacag caaacaaata gactccaact agcaagcctg cactcaaacc tagtataagg
     3001 ataatctttg ttagatgata acgacgccag aattttcgaa tcggacctac ttgggctaat
     3061 ttttttcgat cactacgaga gcgacgtaag atagtagaat cagagtcctc tagttcactt
     3121 gtttcttttt taaaaagaga aagaaatttc tcaaataatt tatctaattt catgcgttta
     3181 ttttatcatc ttcatcatag gaagacaaga atttagctat ttcctatcca aatagggctt
     3241 tttttgttac aatatctgta tgcaattcac atttacatta cccgcctctc tacctcaaat
     3301 gacggtaaag caattacttg aggaacaact cctcatccct agaaaaatcc gtcatttttt
     3361 gagaatcaaa aaacatattt tgataaatca agaagaagtc cactggaacg aaatcgtaaa
     3421 tcctggagat gtttgccagt tgacttttga cgaggaagat tattcccaaa aaacgatccc
     3481 ttggggcaac ccagacttag tgcaggaagt ttatcaagat caacacttga ttattgtaaa
     3541 caaaccagag gggatgaaaa cacatggtaa tcaaccaaac gaaattgccc ttcttaacca
     3601 tgtcagtact tatgttggcc aaacctgcta tgtcgttcat cgtctggaca tggaaaccag
     3661 tggcttagtt ctctttgcca aaaatccttt tatcctgccc attctcaatc gcttattgga
     3721 gaaaaaagag atttctagag aatattgggc tctagttgat ggaaatatca acagaaaaga
     3781 acttgttttc agagacaaaa ttggacgtga tcgccatgat cgtagaaaaa gaatagttga
     3841 tgcaaaaaat gggcaatatg ctgaaacgca tgtaagcaga ttaaagcaat tctcaaacaa
     3901 gacttccttg gctcattgca agctaaagac agggcgaacc catcagattc gtgtgcacct
     3961 tttgcatcat aatcttccta tcctgggaga ccctctctat aatagtaaat caaagacaag
     4021 ccggcttatg cttcatgcct tccgactttc ctttacccac ccacttactt tagagaggct
     4081 aactttcact accttttcaa atacatttga aaaagaatta aaaaagaatg gatgatcgtg
     4141 tcatccattt ttccatataa aaaagcaaga ccacaaagcc ttgctttcta tcaactcaag
     4201 aattatttag caatctttgc aaagtattca agagtacgaa caagttgtgc agtgtatgac
     4261 atttcgttgt cgtaccatga tacaacttta accaattgtt taccgtcaac gtcaagaact
     4321 ttagtttgag ttgcgtcaaa caatgaaccg taagacatac ctacgatatc tgaagatacg
     4381 attggatctt ctgtgtaacc gtatgattcg tttgaagctg ctttcatagc tgcgttcact
     4441 tcatcaacag taacgttctt ttcaagaact gctaccaatt cagtaactga tccagttgga
     4501 gttggaacgc gttgtgcaga tccatcaagt ttaccattca attctgggat tacaagaccg
     4561 atagcttttg cagcaccagt tgagttagga acgatgtttg cagcaccagc gcgagcacgg
     4621 cgaaggtcac caccacggtg tggtccgtca aggatcattt ggtcaccagt gtaagcgtgg
     4681 atagtagtca tcaatccttc aacaacacca aagttgtctt gaagagcttt agccattgga
     4741 gccaagcagt ttgtagtaca tgaagcacct gagataactg tttcagtacc gtcaagaacg
     4801 tcgtggttag tgttgaatac aactgtttta acgtcgtttc caccaggagc agtgataaca
     4861 acttttttag ctccaccttt aaggtgtttt tcagctgctt ctttcttagc aaagaaacca
     4921 gtagcttcaa gaacgatttc tacaccgtca gtagcccagt cgatttgttc tggatcacgt
     4981 tcagcagaaa ctttgatgaa tttaccgtta acttcaaatc caccttcttt aacttcaaca
     5041 gtaccgtcga aacgaccttg agttgtgtcg tatttcaaca agtgtgcaag cataactgga
     5101 tctgtaaggt cgttgatgcg tgtaacttca acaccttcta cgttttggat acgacggaaa
     5161 gcaagacgac cgatacgtcc gaaaccgtta ataccaactt taactaccat tagtgatttc
     5221 ctccttatga aaatcatgaa atttttattg tgaaaagagt aacttgaatc actacaaatc
     5281 acctttcaac aaacctatta tacaactatt tgagttgaat tgcaagtatg gccattgttt
     5341 ttctatgtga gtttcttttt aagactgtaa atcaaggaat cccttattat tcatagcgta
     5401 acgattctac aggatccatt ttactaatct tacgcgccgg gaagtaggct gagacataac
     5461 caagtaatag agcgaaaact agagttccta aaacagataa aagatttaat tcaaaaacct
     5521 tagtgatgga tgggtaaaag tgacttacaa tcgcattcgc caaacttccc accccttgtg
     5581 caaccaaaaa tgccagcagc aaggcgatgc ctacaatcca gatagcctcg taaataaaaa
     5641 ttcctttgac accacgattc tgataaccaa ctgctttcat gacacctatt tccttggaac
     5701 gttgcatgat attgatgtaa ataatgatac caatcataac cgctgctacc acaatagctt
     5761 gtgatgaaag cacaatcaat aatccctgaa taacacgaat aaaggtaatc acaatatcaa
     5821 gaactctctg ttgagaaagc acagtatact tcttattttt ctgtaattct tctgttacta
     5881 cttttgtctg tgatggatct ttgagttcca agataaaata agatacagct ttcgtaaatc
     5941 cagcctcttt caaaatcgtt tccatttgat gagacagcat gaaactgttg ctgtcctcca
     6001 tgtcatcttc atcattgatt acacgtacaa tcttcgtttg aaattgagca atcttactag
     6061 tttcggcagc actttctaca atgctggctg agactgattt gccaataaga tcattagttg
     6121 tcaaattttt tcctgtctgt tcattccaat tttttagtaa actgcttgga atcgttaatc
     6181 cctgttcatt tgtttcagta tagagggatc cagtcaacac tttgtccgtc tcattattac
     6241 taacagagat acttgtatca ttataaagac tcactacttg agcataagaa gcatcgtttg
     6301 actcagatcc atttcttgcc catcttttct tgcccatcta tagtaatatt tgacatgttc
     6361 atcccaaaag gactctccaa atatttaata gcttctttcc caactgtatc cgtgaactat
     6421 agtcaattga aacaagagca ggacaaaaga gcctcataaa aggtattgca acttggtaat
     6481 acctttttga ggtgcttttt gatatgagcc catgttttct caataggatt gtactcaggt
     6541 gagtagggag gaagaggtaa aagtttatgc ccaaactcct cgcataaaag ttctaactta
     6601 cccattctat ggaatcttgc attatccata ataataaccg atggtgtggt taatgttggt
     6661 aagagaaact tctgaaacca agcttcaaaa aagtcgctcg tcatcatctc ttcgtaagtc
     6721 attggagcga ttaactcacc atttgttaga cctgcaacca aagaaatcct ctgatatctt
     6781 cttccagata ctttacctct tcttaactga ccttttaatg agcgaccata ttctcgataa
     6841 aaataagtat cgaatcctgt ttcatcaatc taaacaggtg ctaggtgctt taaactatta
     6901 aaatttttaa gaaataaggc tactttttct gggtcttgtt catagtaggt gtggttcttt
     6961 ttttcgagtg tagcccatag ctttgagcgc atagtggatg gtagttggat gacagccaaa
     7021 ttcagaagct atttcagtca aataagcgtc tggattgtca gtaagatagt ttttaagtct
     7081 atctctatca acctttcttg gttttgttcc ttttacttgg tggtttagct ctcctgtttt
     7141 ctcttttagc tttaaccagc cataaatggt attacgtgag atttggaaaa cgtgtgatgc
     7201 ttctgttata ctacctgttc gctcacaata agagagaact tttttacgaa aatctattga
     7261 atatgccata aaagattata ccacattgtg tactattttt ggttcatttt actatatttg
     7321 aagaggcgtt taaactatct gacataaaac tcgttctaga ggaaagacat cctttaaaaa
     7381 gttagtttat tttacaactt agacatcaag gtaggttaaa cccttcatgg aaaaatcaag
     7441 actcttagca ctatgggtta aactaccact ggagacgtaa tcaatcgcta aaccacgaaa
     7501 acggctaata gtggtcatat caatatttcc agaacattca atccgagaac gtcctgcaat
     7561 tagggtaatg gcctgttcaa tctgttccaa tgacatatta tccaacatga taatatcagc
     7621 acccgccgcc gcagcttctt cggcagcagc aaggctttcc acttccacct cgaccatttt
     7681 cacaaaaggg gcataggcac gcgcttgagc aattgccttt tgaacactac ctactgccgc
     7741 aatgtgattg tcttttagca tgatagcatc tgataaatta aagcgatgat tatagccacc
     7801 gccaactctc acggcatatt tctcaaaaag acgtaaatta ggagtagttt ttcgagtatc
     7861 aaatacctta atgcaatcat cgcctaaggc ttctacataa gcagctgtca tcgaagcaat
     7921 ccctgataaa tgttgtaaaa aattcaaggc aacgcgttca catgttaaga gacttctcac
     7981 cgagcctatg atttctaaaa ccaaatcgcc actagtcaaa cgatccccat ccttaaattg
     8041 atgaggattc tggaaggtca cctcggcatc aaatagggta aaaacccttt gaaaaacggt
     8101 tagtcccgct aaaacaccag cttccttggc aaaaagcgac accttggctt ggccatgatg
     8161 atcaaaaatg gcattggtac tgtaatcttc ggaatgaaca tcttctcgca aggctgcttt
     8221 caatgtatca tctatttgaa aaggggttaa atcagttgaa atgattgaca tcactaagtc
     8281 ctctattttt aatatcactt gtaagcacta gaggcaatta ctattaactt ccataggaaa
     8341 tcacaagcct gaatacctca tttttaattc taacaagtgt caatacaatt gtcaagacaa
     8401 ttgtattttt tttgtgtata atagtcaagt accaatagga aacaggtggt cttttgagcg
     8461 ccaaaattgc caacctattt ccatattcta actgaaagga caattcaatg attcatttaa
     8521 taatgattag cgccattgct ctagccattg gaattggtta ccgcaccaaa atcaatattg
     8581 gcctgctggc tattgctttt tcttacctca tcgcaaccac tctcatggga ttaagcccca
     8641 aagaacttct tcatttttgg ccaacctcac tcttttttac catttttagc gtctctctct
     8701 tttataacgt tgcaacaact aacggtactc ttgatgtttt ggctcaacac attctctacc
     8761 gcacacgcac ccaccctaac gccctctaca tgattttata cctgatggca acccttttgt
     8821 ctgctttagg tgctggattt ttcactacta tggccgtttg ctgtcctcta gcgattaccc
     8881 tctgtcaaaa agcggacaaa caccctttga ttggagctca agccgtcaat tggggagctt
     8941 caggaggggc taatttgata accagtagct caggcattgt ctttcaaggc ctgtttaagc
     9001 aaatgggatg ggaagagcaa gctttttcac ttggcaatca tatctttatc gtcagcatta
     9061 tctacccact catcgtcttg cttttattat cctgttacag tcactatagt aagggaagaa
     9121 caaactcatc cttgactatt gaccaaccac cactcctcag caaggttcaa agacaaacca
     9181 ccttgctcat gatcagcagc atggttttgg tttggctttt tcccttgttg catctcattt
     9241 tcccaaacat cgcctggata gctacttatc aaaaaacatt tgatattggc tttgtctcaa
     9301 tactcatggt ctgcctcgcc ttaaggctca aattagggaa gcaagaagcc attttagcta
     9361 aggttccctg ggctacaatt atcatgctct gcggcatgag cttactaatg tctctagcgg
     9421 tcaagtcagg tttagtcaca ctgatagggc acctcatgac aacaaccatt cctcatttct
     9481 ggttacctct gttcttttgt gtgatagccg gagtgatgtc actctttagt tccaccctat
     9541 ccgttgtagc tccagccctc tttcccatca ttgctatcat cagtgctcaa aatcctcaga
     9601 ttgatattca cttactcaca acagccaccg ttattggcgc tctatctact aatatctcac
     9661 ccttttcatc agctggttct ctcattcaac tctcacttcc caatatagag gaacgtggcc
     9721 ttgccttcaa aaagcaaatt attctgggtg tccccatcag cttaagtttg ggactcttga
     9781 ccacctggat tctcatcctt ctagcttcct taagttagat ttattatcta acttaagggt
     9841 ggacttggta taataaagta gacacaaaat taagtggaaa cgaggaaaag tcattatgcc
     9901 aagaaaaacc tttgataaag ccttcaaact ctctgctgta aatctcatcc tgtaaaaatg
     9961 attagttcaa ctttaaaaat tcatcccaat agtctttatc gatggattca agaatatgaa
    10021 aaatatgaag aaagtgcgtt cccaggacat gggagcgcac ttcgtcatac tcaatttgag
    10081 atatagtgaa atgaaataag aacaggacaa atagatcagg atagtcaaat cgatttctaa
    10141 caatatttta gaagtagatg tgtactattc tagtttcaat ctactatagt aaagttgact
    10201 ttcctgtacc atttttacca gtaattaatg tcacgcctga actcgaagta tcaaaagaaa
    10261 tattatcaaa caatatacga tgatccaccc tatacgaaat attttctact ttcatttttt
    10321 ctccttttga actaatagca aaagaaacag ttctgttttc atactctttc cccttcatct
    10381 atattattcg taatgaaaaa taaaaaaata aaattttttt aaatgattat gattcagaat
    10441 ttattcaata tattaaaaca atatttgaac aaataaattg ggagattgaa attcatttct
    10501 agcaatttgt tagaagtcac agtctactat tctaacctca gtatactata tgtgttacaa
    10561 gaaaagactc aaaaacttct cgtcagtgta agaatatttg aaacactatt taaaactaaa
    10621 taactataag aagtagatca ggtgaacaat ttcagtacct actctataag ctatacgaag
    10681 atatttttca acatgatgga tacaacgatc actcttttaa agccatctta tttagaaaag
    10741 agaaaccatt taagcataga tgggaccttc ttgccctgtt ttaaattttt cttaaactag
    10801 agtctgtaaa agattggctt cattttcaca ttttctccta ggaggaatgt cgtaatgcaa
    10861 aagaattaaa ttcaaataaa tcatagcgat gacgactaat cgagtactca aacggagttc
    10921 cgttatccaa ataagccact tgttctactt caaataccgg ttccgttgga aggagctgca
    10981 agtaatgttg ctcattttct gaactagaag aagctcgcaa gatttttgta gcactggcaa
    11041 tatgcaatcc taactttcct tcaatgtaat tgtaaatcga tttttgtaaa atatcttcag
    11101 taatacctgg aataacatcg gtactcatat aagtttgttc cagaacataa ggtttaccgt
    11161 caataatacg cagacggtaa atattataaa ctggactctg caaagcgacc tgtagttttt
    11221 ctgctaaaaa ttcatttgca aattctaatt tgaagtgaat aatcctcgag tcaattgtag
    11281 aatgagcatc ttcagatatt tttgtcagtc cccggatatc tctttctgga acgattaatt
    11341 ttctttttga gctgccacga gagagaacaa aggttccctg cccacgtttt ctaaaaatta
    11401 agccctcaga aactaacaag tctaaagctt ttttgatcgt cattcgacta caggcaaact
    11461 gtttagctaa tgtcatttca tcaggcaatt gttcgttcat ggtatattta ttacaaagaa
    11521 tcttttcacg aatctcattg taaataaata aatattttgt actcatttaa tctggttctc
    11581 tctataatat tctaatagta gtataacaaa gttcaagaaa tgaggcaaac acaagatatg
    11641 tatcaacaat ttttaaaaat gtctagacaa atttgaaaat catgctatac tttatgtata
    11701 gaataataga aaggaggttg agcatgaaaa aaaaagttag tatttcctaa tctattttgg
    11761 tggggagctg cttctagcgg acctcagaca gaaggtcaat atggaaaagt acatgaaaat
    11821 gtgatggact actggttcaa aacgcatcca gaagattttt tcgataatgt cggacctctt
    11881 gtagccagta acttttttca tacttacacc gaagatttcc acttgatgaa ggaaattgga
    11941 gttaattctt tccgcacttc catccaatgg agtcgactca tcaagaattt agagacaggt
    12001 gagcctgatc caaaaggtat tgctttctac aatgccatca ttgaagaagc taaaaagaac
    12061 cagatggatc ttgtgatgaa tttacatcat tttgatttac cagtggaact tcttcaaaaa
    12121 tacggtggtt gggaaagcaa acatgtagtg gagttattcg tgaagtttgc caagactgct
    12181 ttcacatgct ttggagataa ggttcattac tggacaactt tcaatgagcc aatggtcatt
    12241 ccagaagcag gatacttata tgctttccat tatccaaatc taaaaggaaa gggaaaagag
    12301 gccgtacaag tcatctataa tctaaacctt gctagtgcaa aagtgattca actatatcgc
    12361 tcattagaac ttgatggaaa gattgggatt attttaaact tgacacctgc ttatccaaga
    12421 agtaattctc cagaagactt agaagcaagt cgatttacag atgacttctt taacaaagtc
    12481 ttcttgaatc cagctgttaa aggaactttc ccagaaagat tggtaaaaca gctagagaga
    12541 gatggcgtgt tatggagtca taccgaaaaa gagcttcaac tgatgaaatc aaatacggtt
    12601 gattttcttg gagtaaacta ctaccatcca aaacgtgttc aagcacaagc aaatcctgag
    12661 gaatatcaga cgccctggat gccagaccaa tacttcaaag agtatgaatg gctggagcgt
    12721 cgcatgaatc catatcgtgg ttgggaaatt tttccgaaag ccatttatga tattgctatg
    12781 attgtgaagg aagaatatgg taatatccca tggtttatca gtgaaaacgg aatgggtgtt
    12841 gaaaacgaag cacggtttat cgatgaaaat ggagttatcg atgacgtgta tcgtattgaa
    12901 ttttatgaag aacatttaag atggctacat aaagccattg aagagggaag tcactgtttt
    12961 ggataccacg cttggaccgc atttgattgc tggtcttgga ataatgcata taagaatcgt
    13021 tacggattta tctccgttga tttagaaacg caaaagagaa ccatcaagag ctcaggaaga
    13081 tggtatcgca aagtaagtga caataacggt tttgaagtag aaattgagga gtaaagagag
    13141 gagatattca gatgaaaaac tcaaaattta tagatcaatt tgccaccttt gctggtaaac
    13201 tagggaacca aattcattta aaaaccctaa gagatgcatt cgtaacagta atgccattat
    13261 atattttggc aggtttaatc gttcttttga acaacacggt atttaagtgg attttccaag
    13321 gggatacatt aacaagattc caatattggg gaataacaat tgcaaacggt actttaagta
    13381 tttcaggtat gattattgct gtaatggttg gttatttctt agctaaaaac agagatttcg
    13441 aaaacccgtt agcagcagca atgctatcat tagtttcttt aattgtgatg atgccaaata
    13501 cagtttctgt agttcctgac ggagcaaaag atgcggtaaa catttcaggt gttctttcat
    13561 tcaacaacac aggtacaggc gcaatgttcg ccggggttat cgtagcgatt attgcaacag
    13621 aattattcat tgaattatca aacgttaaag ctttacaaat gaaccttggt gaaaatattc
    13681 caccagctgt tagtagatca tttagcgtat tacttccagt catgaccgtc atctccttat
    13741 ttggggttgt ttcagcatta ttattcaata taactggaat gaacttaatc tcaatcatta
    13801 caatctttat tcaagaacca attcgtcata ttggtacaag cttaatcggg gtcattatta
    13861 tttactcttt aggaaatatg ttatggctat ttggtattca ccaagcagtt atttacagtg
    13921 ccatcctaga accattacta ttaattaaca ttactgaaaa catcactgca gcaaataatg
    13981 gacaagccat tccacacatc atcaacctat cacaaataca aacattcgct ttaatgggtg
    14041 gtagtggatc tacattatgt ttattaatag caacattctt agtaagtcgc aatgctgttt
    14101 ctaaaaacgt ggctaaatta tcttttggac ctggtatctt caatatcaat gaaccagtat
    14161 tattcggtta cccaatcgtt tataacattt cattagctat tccatttatc acagttccag
    14221 tccttggtat tttaatcagc tacttagcaa cagttacagg attcatgagt cctgcattta
    14281 tacaagttcc ttggactaca ccagtattct taaatgcatg gttagcaaca gcaggggacg
    14341 tgagagcagt tctagttcaa ttcatcatct ttgcacttgg agttcttcta tacattccat
    14401 ttatcaaagt taatgacaaa gttgttgaac aaaaaatgga aggttaagat tatgaaacaa
    14461 attttattag tatgtaatgc gggaatgtcg acaagtatgc ttgttaaaaa aatgcaacaa
    14521 agtgcgactg aacgtgggat tgaaatttct atccaagcaa aatcaatgac agaagctaaa
    14581 aagaatatcc atgaagcaga tgtcattcta attgggccac aaattcgtta tgagttactt
    14641 gctgtgaaag aaattgcagg aaatatccct gtagatacca ttgatatgcg ggattacgga
    14701 atgatgaatg gagcaaaagt tctggaacaa gcacttgcat ggataggaga aataagatga
    14761 cagaagaaat ggaatatatc tgttttcagc tcattgccaa tagtggagca gccaaatcat
    14821 cctttattga agccatccaa ctagctaagg caggaaattt aaaagaagcg aaaattaaag
    14881 ttgaagaagc ggaagactcc ttagtagaag cgcacaagat tcactctaat ctcatacaaa
    14941 aagaagctac tggagaaaaa ataggattct ccttgctatt tatgcatgca gaagcccaaa
    15001 tggcttcaac agagattatt cagttgctat ctaaagaatt catcgatctc tatcaaaata
    15061 aataggaaca ctgtcattcc catctgtctt tattaatgac gactacattg taggaacctc
    15121 caaaagttgg acaaaatgat tgaaaggatt ggatcctgca ttacacaaga tccaatcctt
    15181 ttcttttact ctagttttta taatatgttg aatctagaat agtccacagc agtttctaaa
    15241 aaatttctgg aaatggatgt taagctccaa tttatttgtt tatatcttat ttcagtttac
    15301 tatactagct tattattcta gtgaaaaatt gaatgagcca ctatttattt aatatgtatg
    15361 atgagggaat gactcaaaaa cttcttgtcg atataagaac atctgagata gtattttaaa
    15421 acgaaaggac tataaaagct catttccttc gcacttattt tatagagatc tatcattata
    15481 ctctttagaa atcaaaaagc aacacacctt gtcatcgttt tatcgtaaat ctgttaatga
    15541 gggagctagt cttatctgca atctcaaatc agtgttttga gctgaatggc actcgttttc
    15601 tcgtttgctc tttgatttta attgggcctt agtaaatact actcttaaat taaactatag
    15661 tgaattgaaa taagatgtga acaactctat c
//
LOCUS       DAVMBH010000045        14135 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVMBH010000045 DAVMBH010000000
VERSION     DAVMBH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.045"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            81..878
                     /locus_tag="VYP30_001653"
     CDS             81..878
                     /locus_tag="VYP30_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1808615.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VYP30_001654"
     CDS             1026..1148
                     /locus_tag="VYP30_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV1808616.1"
                     /translation="MTCDFKSETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1170..2210
                     /locus_tag="VYP30_001655"
     CDS             1170..2210
                     /locus_tag="VYP30_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1808617.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDHLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2381..3655
                     /locus_tag="VYP30_001656"
     CDS             2381..3655
                     /locus_tag="VYP30_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1808618.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VYP30_001657"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VYP30_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1808619.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VYP30_001658"
     CDS             4784..5086
                     /locus_tag="VYP30_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1808620.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VYP30_001659"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VYP30_001659"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1808621.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VYP30_001660"
     CDS             5960..7300
                     /locus_tag="VYP30_001660"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1808622.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLIIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VYP30_001661"
     CDS             7278..7490
                     /locus_tag="VYP30_001661"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1808623.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VYP30_001662"
     CDS             7487..8362
                     /locus_tag="VYP30_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1808624.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VYP30_001663"
     CDS             8355..9170
                     /locus_tag="VYP30_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1808625.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VYP30_001664"
     CDS             9163..9594
                     /locus_tag="VYP30_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1808626.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VYP30_001665"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VYP30_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1808627.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEADIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VYP30_001666"
     CDS             11270..11998
                     /locus_tag="VYP30_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1808628.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRSEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VYP30_001667"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VYP30_001667"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1808629.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13981..>14135)
                     /locus_tag="VYP30_001668"
     CDS             complement(13981..>14135)
                     /locus_tag="VYP30_001668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808630.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSNHTYGKATLTWFEEI
                     FEEYKN"
BASE COUNT         4166 a         2583 c         3370 g         4016 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgat acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaatga tatggaggtc
     1021 accttatgac ttgtgatttt aaatctgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgcttgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatgttgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaactc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaatacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gatggcttca gggaaattcc ctcaatttgt tgacgagggt tcaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagtagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaagatgt cggttcaatc tttaccttcc
     2041 atgtcaaagg tggcgaggaa gaagcacgca aggtcattga tcatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 tgagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aaggatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcagacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gccgataatg actactttaa
     3241 cacagggatt gttgacgtca gccacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccag ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aattactctg ggttattcca cgacgactga
     3901 ggatgctagt ggggaagtga tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga tcatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctctttcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggaa
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccataa aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaaatatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc taccccaatt
     6361 ttctaagaga attggggtgg taaccagccg tagtggagcc gttattcgag atattatcac
     6421 aaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgatc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttgccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagagaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attgccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgtaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtattgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagct atgaatgaca tggaaagtgt cgaagagtat
    10381 gatcctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctgatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgacatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaatgaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagtatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caatttttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acagtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc ttaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaagtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcggcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atctttgttc acgcaggtat
    11701 tgatttgacc ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttattcagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taaaaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ctgtgttttg aacaacctgc
    14101 ggctagcttc ctagtttgct ctttgatttt cattg
//
LOCUS       DAVMBH010000046        14003 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVMBH010000046 DAVMBH010000000
VERSION     DAVMBH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.046"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(176..613)
                     /locus_tag="VYP30_001669"
     CDS             complement(176..613)
                     /locus_tag="VYP30_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1808631.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(698..3331)
                     /gene="polA"
                     /locus_tag="VYP30_001670"
     CDS             complement(698..3331)
                     /gene="polA"
                     /locus_tag="VYP30_001670"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1808632.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELMDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEIKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3582..3932
                     /locus_tag="VYP30_001671"
     CDS             3582..3932
                     /locus_tag="VYP30_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1808633.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4147..4263
                     /locus_tag="VYP30_001672"
                     /pseudo
     CDS             4147..4263
                     /locus_tag="VYP30_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
     gene            4256..4489
                     /locus_tag="VYP30_001673"
     CDS             4256..4489
                     /locus_tag="VYP30_001673"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808634.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            4616..4894
                     /locus_tag="VYP30_001674"
                     /pseudo
     CDS             4616..4894
                     /locus_tag="VYP30_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5031..5999)
                     /locus_tag="VYP30_001675"
     CDS             complement(5031..5999)
                     /locus_tag="VYP30_001675"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1808635.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(6144..6767)
                     /locus_tag="VYP30_001676"
     CDS             complement(6144..6767)
                     /locus_tag="VYP30_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1808636.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIAFYGFYHAYCFVEKHNELMT"
     gene            complement(6749..6958)
                     /locus_tag="VYP30_001677"
     CDS             complement(6749..6958)
                     /locus_tag="VYP30_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808637.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            complement(6983..7480)
                     /locus_tag="VYP30_001678"
     CDS             complement(6983..7480)
                     /locus_tag="VYP30_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1808638.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(7553..8914)
                     /gene="radA"
                     /locus_tag="VYP30_001679"
     CDS             complement(7553..8914)
                     /gene="radA"
                     /locus_tag="VYP30_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1808639.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(8928..9443)
                     /locus_tag="VYP30_001680"
     CDS             complement(8928..9443)
                     /locus_tag="VYP30_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1808640.1"
                     /translation="MKIIFVRHGEPDYSELEERSYIGFGINLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(9445..9888)
                     /locus_tag="VYP30_001681"
     CDS             complement(9445..9888)
                     /locus_tag="VYP30_001681"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1808641.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(9945..10042)
                     /gene="ffs"
                     /locus_tag="VYP30_001682"
     ncRNA           complement(9945..10042)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYP30_001682"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10075..10542)
                     /locus_tag="VYP30_001683"
     CDS             complement(10075..10542)
                     /locus_tag="VYP30_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1808642.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(10743..12029)
                     /locus_tag="VYP30_001684"
     CDS             complement(10743..12029)
                     /locus_tag="VYP30_001684"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1808643.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(12260..12496)
                     /locus_tag="VYP30_001685"
     CDS             complement(12260..12496)
                     /locus_tag="VYP30_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1808644.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGNNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            12762..13517
                     /locus_tag="VYP30_001686"
                     /pseudo
     CDS             12762..13517
                     /locus_tag="VYP30_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13552..13761)
                     /locus_tag="VYP30_001687"
                     /pseudo
     CDS             complement(13552..13761)
                     /locus_tag="VYP30_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13927..14000)
                     /locus_tag="VYP30_001688"
     tRNA            complement(13927..14000)
                     /locus_tag="VYP30_001688"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13964..13966),aa:Asn,seq:gtt)
BASE COUNT         4424 a         3330 c         2357 g         3892 t
ORIGIN      
        1 cggtgttttg agctgacttc gtcagttcta tctacaacct caaaacggtg ttttgagctg
       61 acttcgtcag ttctatctac aacctcaaaa cggtgttttg agcagcccgc ggctagtttg
      121 ctctttgatt ttcattgagt ataacacaaa aggtagccca tcagctacct ttttcttatg
      181 cttcctcaat caagcgagta tgttctctct tgatacagcg attcatcacg atatcatcac
      241 atccaccatc acgcaaaatc tctttcgctt ctaaactttc aagtcctagc tgtgcccaaa
      301 aaatcttggc atcagctttg agaaaatcac gcgccacatc gggcagaaat tcactgcgac
      361 gataaacatt gacaatatct acaggaaaag gaatttcagc gaggctagca taagcctttt
      421 cacccaagat ttcgccacct gccgccttgg gattgactgg gatgatttta tagccccgag
      481 cctgcatttc ctttgttact cgattgctgg ttgtttcttc acggtcagac aaacccacca
      541 cagcaagggt tttactcgtt gcgagatact gacgaatcac gccatcactt ggattgataa
      601 attcttgact catagaaatc ctcctttttc atcagtatag cacattttga aaaggtttgc
      661 agaattctac tacaaaaaag gaggactagc ccccttttta tttagcctcg taccaggttg
      721 ccccttcatt ctcatctgcg ataagaggaa cactgagttg aatggcttct tccatggttt
      781 gtttcaccaa tttttttatc tctaccaatt cagatttagg cacttcaagg acgatttcat
      841 cgtgcacttg taacagcatc ttagtctgat aaccacctgc aaccaaggct ttatccagct
      901 gaatcatggc aatcttgaga atatctgctg ccgaaccctg gataggtgag ttgatagcag
      961 ttcgctccgc aaaaccacga atattgaagt tgcgcgaatt gatatctggc aactcacggc
     1021 gacgcttaaa gagggtctct acatagccct tatcacgcgc ctcccgcacc acttcatcca
     1081 tgtagttttt aatacctgga aaacgttcaa agtaggtatc aatgtaggct ttggcttcct
     1141 tacgactaat tcccaaatta ttagacaagc caaagtctga aatcccataa accactccaa
     1201 agttaactgc cttggcattg cgacggtcat ttgcagtcac attatcagga cgctcaatgc
     1261 caaagacccg catggctgtc gaagtatgga tatctgcccc ctcttggaag gccttaatca
     1321 agtgctcatc cttagaaata tgcgccaaaa cgcgcaattc aatctgtgaa taatcagagc
     1381 tgagtagcac actatcctcc cactctggca caaaagcctt ccgaatcaag cgcccttgtt
     1441 ccaatcgggc aggaatattt tgcaagtttg gatccacact agacaaacgc ccggtctggg
     1501 tcaaatcctg cacatagcga gtatgaatct ttccatcagc caaaatccag tcctgcaagc
     1561 caattacata agtagattga atcttagcaa tttgacggta atccaggatt ttcttaacaa
     1621 tcggagcaat aggagcgaga cgctccaaaa catccactgc tgtcgaataa cctgtcttgg
     1681 ttttcttagt gtattctaga ggaagtccca atttctcaaa gagaagcacg cccaactgct
     1741 taggcgagtt gacattaaac tcctcaccgg ccagctcgta aatctcttga gtcagttttt
     1801 caatgacaag ctcattttca gcctgcatct caagcaaggt ctctttcttg accataatcc
     1861 cagcaatttc catcttggca aggacaaaag ccagaggttg ctccatatca taaagaagct
     1921 ctaattgccc attttcgctg agtttttcaa gtaaaatagg ctctgtttct accaaaacag
     1981 caagtttaca agctaagtgt tccaagaatt tctcacgttc aggaatggcc tttttaacac
     2041 ccttaccgta gaaagtttca tcatcaacca agtaagtctg accataaaga ctagcgatgg
     2101 tcgcaatttc attgtcctcc acagtcgaaa ggaggtattt agccaaacgg atgtcaaaag
     2161 caggcgcctg caaatccaca ccaaaacgtt gcaaaagaac tttaaccttc ttaaagtcat
     2221 aaactctcag agatgttttt tctaagaaat ccttgaaaat cgggtcttgc aacagttcaa
     2281 gcttgtctgt ggcatagagc ttatccccac aagaccaggc aaatccaacc aaattatccg
     2341 tatggtaatt ctcaccaaaa agctcaaagt ggaagataga ctcttcactc agcatatctt
     2401 gactgatttg gtcaacaata gtaaaatcca aactctcaga cacatcagct gacgacacat
     2461 ttaaagcctg cttgagctgt ttgaagccca tctcatcgta gaatttccca agattttcaa
     2521 catctggacc actatagacc aagtcctcta aaccaatcgc aatcggtgcc ttggtatcaa
     2581 tggtcgctag tgttttagac aaaaaggcct gttccttgtc attgatgaga ttttccttca
     2641 tcttagaagt cttcattcca tcaatatttt cataaatccc ctcaagcgaa ccatgctcca
     2701 gcaagagctt aatacccgtc ttttcaccga ctttggtcac cccagggata ttatccgact
     2761 tatcacccat gagcgccttg agatcgataa actgagctgg tgtgaggccc atttcttcca
     2821 tgaggtaatc tggcgtaaag gcctcaaact cagccacacc tttcttggaa atttcaacca
     2881 ccgtatgctc atccgtcagc tgaatcaaat ccttgtcccc actgacaatg gtaatatcaa
     2941 aaccatcctg ctctgctagc ttatccagcg tcccaatgat gtcatccgcc tcatactgag
     3001 ccagctcata gtgacgaatc cccatatgat ccatcaactc acgaatgaaa ggaaattgct
     3061 cacgaaactc atcaggagtc ttggcccgac cacccttata gtccgcatac atctctgtcc
     3121 ggaaggtcgt ctttcccgca tcaaaagcca ccaaaatatg actcggctca acccgctcca
     3181 acaaatgact caacatcaac tgaaaaccat aaatcgcatt ggtatgcaaa ccagccgcat
     3241 tcttaaaacg gtccaactgc tgatacagcg caaaaaacgc ccgaaaagct acagaagacc
     3301 catcaatcaa taataatttt ttcttatcca tacacccatt ataaaggaaa gaatcaaaaa
     3361 ataccattgg gaagagctag agcaagtatt tttcaaactt tttccgaata aatagataga
     3421 gccagagaat ttagtaaacc tagatttaaa aatgtgctat aatatattga atctataata
     3481 gtacaccttg actgctaaaa tatttctata aattaatttg actttcctga tagagttatt
     3541 cacatcttat ttcaactcac tatagaagga ggaataggag gattctcaga catccgggca
     3601 tcagcccaac taatgatttg attgctaaga aaatattcag caatccagaa atcacttgtc
     3661 aatttattcg cgatatgctg gacttgccag caaaaaatgt gaccattttg gagggaagcg
     3721 atattcacgt attactctcc atgccttact cagcgcagga tttttatacc agtatagacg
     3781 tcttggcgga gttggataac ggtactcaag taattattga gattcaagtc catcatcaga
     3841 attttttcat caatcacttg tggacttacc tgtgcagtca ggttaatcaa aatcttgaaa
     3901 aaattcgtca gcgagaaggt gatactcact agagctacaa acacatcgct cctgtttacg
     3961 ccattgctat cgtggatagt aattatttct cagatgacct ggcttttcat agctttagta
     4021 tgcgcgaaga cacaacaggt gaggtattgg cgattaccaa caatggacag gaaaaccatc
     4081 tggttaagat ggcattcttg gaattaaaaa atacagagaa accagcaagg acgaggttcg
     4141 caagccatgg ttggagtttt tcggcaacaa gccctttacc cagcaaccgc aacgagccat
     4201 tagccaagca aatcaactgc tggactacaa gagctggtcc gaggaggaca ggaaaatgtt
     4261 tagtcaacta catatgcgag aagaacaagt cttgttagca caggactatg ccttggaaac
     4321 tgctagggct gaaggtcttg aacaaggact agagcgtggg aaagttgaag gaagggcaga
     4381 aaggaaactt tttgccttcc tagacatagt acgccaaggt cttctgactt ctgaggttgc
     4441 cagccagcaa ttaggtatgt cagtatctga atttgaggca ctgttgtaaa atggctccat
     4501 aatatccata gtgggtaaat cccctatgga tattatggag cctattttgt gtagaaaaaa
     4561 agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga
     4621 acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc agattttaaa
     4681 catcatcaat aaggatacac acaaggaaat catcgccaaa ctggactacg acgccccatc
     4741 ttgccctgag tgcggaaacc aattgaagaa atatgacttt caaaaacctt ctaaaattcc
     4801 ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc gattcaagtg
     4861 ctatcactgt tcaaaaatga tggtcgctga aacttatgat gacgtacagt catatttctt
     4921 ctctttttat tatatcacag ttttaaatct agctttacta gattcaccgc tactatctat
     4981 ttattcggaa aaaagacgaa aaaacctgag aatcatctca ggcttggtca ttaaattttt
     5041 ttctcaatat cgaaaagtgg agaaagtggt cgtttttcat gaatacgtac gatagcatcc
     5101 cctaggagat gagcgattga aatctgctca atcttatcaa tcaaacgctc ttctggcaga
     5161 tagatggtat ccaaaacaac caatttctta atagctgatt tttggatatt gtccgtagca
     5221 ggaccagaaa gaactgggtg cgtacagctt gcatagactt caacagcacc agcttccgca
     5281 agagcatctg ccgcatgaca aatcgttcca gcggtatcaa tcatatcatc aatcaagata
     5341 caagtcttgc cttcaacctt accgatgatg ttcataactt cactagtatt catcttatca
     5401 acgctacgac gtttatcaat aatagcgata gatgttttca aaaattctgc caacttacga
     5461 gcacgagtca cccctccatg gtccgggctg acaaccacat agtcagaacc aaccatacca
     5521 cgacgctcaa aataatctgc aatcagagga gcacccatca aatgatccac aggaatatca
     5581 aagaatcctt gaatttgcgc agcatgcaag tcgatggtca ataaacgatc cactccagct
     5641 acttcaagca tatttgcgac aagttttgaa gtgattggct cacgcgctct cgcctttcta
     5701 tcctgacgtg catacccata gtaaggcatg acaacattga cagattctgc actcgcacgc
     5761 ttcaaagcat ctaccataat caaaatttca agcagattgt catttacagg cgaactagtt
     5821 gattgtagga taaagacgtg tttcccacgg attgattctt caatgttgac ctgaatctct
     5881 ccatctgaaa attggcgaac acttgatttc cccaactcta tcccaatctc ctgcgccaca
     5941 cgttctgcca attctttatt agaagaaagg gcaaacagct ttaaatcaga aaaagacatg
     6001 atttcctccg gtatatatgt ataacttgtg cttttcacaa gattttccat ctaccattgt
     6061 agcgcttttt gcactatttt tcaatcaaaa ataaaagaag gacaccatat ttgtaccctt
     6121 gcatcattct tttgaaaaat attctaggtc atcaactcat tgtgtttctc aacaaagcaa
     6181 taagcatgat aaaaaccata gaaagcaata gccgtaacca ctggaatcgc taaaggcaac
     6241 tctgtttcca actccacaaa aggagagtta aacaagaagt gagttcccaa ggctaaacct
     6301 agaaaaataa ggccctgttt cttgccaacc ttctgtcctt tataggctct gtaaagcaag
     6361 taaacaccta ctacagctag acctgaaaaa gtccagtgag aggcaattcc tgagatgata
     6421 cgctctaaaa ttcgcgaaat agtaaaatca aagccctctg gcaaatccgt acgaatataa
     6481 ccaatatcct taatcatttg gaatcccaaa ccggaagcaa ttccaagtaa aaacaaagat
     6541 tttaattttc gcacaggaat caaagccaaa acaaaaacaa gtggcaataa tttcaagggt
     6601 tcttctacca aaggagccac aatagcactt tcaaaggcat ttaaaaatgt actatctggg
     6661 aaaagaaccc ccagtaaatc atggatataa gtattagcaa aactagacaa ccagcctgaa
     6721 aggaacatcc ctcccaataa agacagaatc aaaaccttct ttggcaattc ccatttttcc
     6781 caatacggaa gagaaaataa agagccggaa tcatgtaaaa gagagctaga aagatagaaa
     6841 ctcccattag tccatattcc gcacctgacc tcgaaccgtc cgtatagtag atggtttcat
     6901 actgtaaacc aatacatagc aataaaataa aaataaataa aatactgctt ttcttcatac
     6961 actttctttc taaatgaagt atttataatt ctacgactgt catacttcct gtatcaacat
     7021 tgtaaatggc accagagata atgacatcgt ctggtattag gggagactcg ataagcagtt
     7081 gcatatcctc gcgtacactc tcttctatat cttggaaggg caagaagtcc tggtctgaca
     7141 catctacacc taattcctct tttaaatact cctgaaaagg ttcattttca aaggtctgag
     7201 caccacagtc tgtatggtgc aataccacaa tctctcttgt ccccatttgt tgctgggaaa
     7261 taactagcga acgaatcatg tcttcagtca ctcgaccacc tgcattccgc aagatatgag
     7321 catccccaag tgccaaacct agagcttgcg caacgtgcaa acgtgagtcc atacaggtca
     7381 caatggctac tctggtttta ggtttaagtg gcagatttaa ctgcccatgt agggcaacat
     7441 aagcctgatt ggcttgcata aactgttcaa aatacgacac gattccctcc ttgaaaattt
     7501 gatagtcaaa tatttctcct atcttatcat ttttaagaga atttgtcacg gattatgcaa
     7561 agaccttttt caagacttcc tgaatcgttg tcacgccaat gacctgaatt tccttaggca
     7621 gagtgattcc tgtcaaggaa ttcttaggta cataaatctt agtaaagccc agtttagcag
     7681 cttcgttgat gcgttgctca atacgattca cgcgccgaat ctctcctgtc aagcccagtt
     7741 ctccgacaaa acattcctga ggattagttg gcttgtcttt gtagctcgaa gcaatagcaa
     7801 ctgcaacagc caagtcaatg gcaggttcat ccaatttaac accaccagca gatttgagat
     7861 aggcatcctg attttgcaag agaagccctg cccgtttttc caaaacagcc ataatcaagc
     7921 tagcacggtt aaaatcaagt cctgtcgtag tacgcttggc atttccaaac atggtcggtg
     7981 ttaccaaagc ctgaacctcc gccaaaatcg gacgcgtccc ttccatggtt acaacgatgg
     8041 aggaaccagt cgccccatcc aaacgctctt ctaggaaaac ttgactcgga ttgagtacct
     8101 caaccaagcc gcccgactgc atctcaaaaa tcccaatctc attagtggaa ccaaaacgat
     8161 ttttgaccgc tctcaaaata cgaaaggtgt ggtgacgctc cccttcaaag taaagcaccg
     8221 tatccaccat atgctccaac atacgaggcc cagccaaggt tccttctttg gtcacatgac
     8281 ctacgataaa gatggcaatg ttattggtct tggccaactg catgagttca gcggtcactt
     8341 cacgtacctg agaaacagac ccctgcaccc ctgaaatctc aggagacatg atggtctgga
     8401 tggaatcaat aatgagaaag tctggctgga tacgctccac ttctgcacga acactctgca
     8461 tattggtctc tgcatagaga taaaactcac tatcaatatc acctaagcgc tctgcacgta
     8521 gtttaatctg ctgggcagac tcctccccac tgacatagag aactgtcccc acttgggaca
     8581 actgggttga gacttgtagg agaagagttg atttcccaat cccaggatcc ccaccgatga
     8641 ggacgagact tcctggtacc actccgcctc caagcacacg gttgaattcc tccatctccg
     8701 tcttggttcg attgacattg atggaagtca cctcagctag tttcatgggc ttggttttct
     8761 cacctgtcaa ggacacacgc gcattcttga cctcggcaac ctcaacctct tccacaaaag
     8821 aagaccaaga cccacagttg gggcaacgtc ccagatattt aggggaatta tacccacaat
     8881 tttgacatac aaatgtcgct tttttctttg cgatgacaaa cctctttcta tatctctaac
     8941 tcacactcaa tcacttggca aaaatcaatc ttctcatttg gcacaaactg gcgcatgagc
     9001 attcgatgag caacaactac cacagtctga tgttctcgat acttagacat acattctaga
     9061 aaccgagact tcatttccgt agctgtctca tattgaatag gactattagg aagcaactcc
     9121 cccttgtttt ctaaaaacag tcttctagct gtttcaaagt tttctattcc tgttttatag
     9181 acctgccatt catgtaataa aggctctact cttaaaggaa gacccgtagc acagaccaca
     9241 tacgaagccg tttctaaagc tcttgtgact gcagaagata cgattatttc agctgacgag
     9301 agtaaaggat ttttgctcaa tttctggact tgctgccgtc ccatctcaga caagggtgcc
     9361 aaatttatcc caaatcctat ataagaacgc tcctctaact cactgtaatc cggctcccca
     9421 tgacgtacaa agataatctt cattctagtg ccctgtcgat ccaaatccac cagttcgaac
     9481 gccatcagct gcatctccat ctgcaattaa gaaagtagca aaaacagcct ggacaatacg
     9541 ctccccaact tcaagaacaa cctcttggtc tgtgatattc ttcatctgcg caaaaatatg
     9601 cccttcattt ccaggatttc cataataatc cccatcaatg accccaactg agttaattaa
     9661 aaccaagccc ttcttacgag gatttgaaga acgatcatag aggtagagaa cctcagtcgg
     9721 ctgcatataa gccttaaccc ctgtcggaac caagacaatc tctcctggcg caacaactgt
     9781 acgcacagca acctttaagt cgtaaccagc cgcatgcgct gtctcacgct tgggcaataa
     9841 attttcatct gtaaaactcg aaaccaattc aaaaccacga attttcataa ttttctcttt
     9901 tctattatca tttattctag attattctat cttatttatt cggaaaaagc acgaaaaaaa
     9961 gagcacacaa ttcaaatcgc ttagggctgc tggattcctc ccctgacccg cttcacgcag
    10021 aactgttgct ccactattta ttatatcaca ttcctattca ttttaaaagc aaaattattt
    10081 tttccgtcta tttctaaaaa aatcctgcat gatagctgcg cattcatctt ccaaaattcc
    10141 tatttcaacc tccacacgat gattgagacg ctcatctgtc aagatatcgt acaaactccc
    10201 agcagcgcca aatttctggt ttttagcccc atagaccaca tttggaatgc gggcaagccc
    10261 aatcgcccca ctacacatga cacaaggttc aatggtcaca aaaagtgtgc aatccagcaa
    10321 gcgccagctc tcctcactca agttcgcatc ctctatagcc ataatttccg catgcataac
    10381 cgctcgctgt aattcctcac gcgcattatg cccacgacca atgatttccc catctttgac
    10441 aatcacacaa ccaattggaa tttcatcgtg ttcaagagca atctcagcct ctctcaaagc
    10501 ctccctcata aagacttctt tttcttcaag cgtataatac atctcttttc tcttttccta
    10561 cttatcgatt ttattattat atcatgaatc ccaacacaaa aaaagccacc gaatgcggtg
    10621 actctatagg gagattatta tgaaaaagaa aagtttagga tatttgttac aacaagttag
    10681 gaggtcttct tgtaactgtc tatagtatac ccgacctatc ttaaacaaat cttaaaaatc
    10741 tcttaggacc aaacactttc taaaatattt gtttgttcac gaccaggacc tactgagaaa
    10801 gtagaaatac gaacgccaac caattcactc acacgacgaa catagttacg cgcattctca
    10861 ggaagatctt ccaaattgcg aactccggta atatcttctg accaacctgg caactcttca
    10921 tagataggct tgcaacgttt caattgctca agactagctg gatagtagtc aatacgttga
    10981 ccgtcaagat cataggccac acagattttc acagtatcca aaccgctcaa aacatcaata
    11041 gagttcaaag aaaggttagt aataccagaa acacgacggc tatgacgcat cacaactgag
    11101 tcaaaccaac ctacacgacg tggacgacca gttgttgtac catactcatg acccacttca
    11161 cggatacgtt ctcccacttc atcaaacaac tcagttggga aaggaccatc tcctacacga
    11221 ctcgtataag ctttacatac acctacaacc ttgtcaatct tgcttggacc gacaccagaa
    11281 ccaattgtca caccaccagc tacagggttt gatgacgtaa caaatggata agtaccttgg
    11341 tcgatatcta gcataacacc ttgtgcacct tcaaaaagca cacgtttgcc attatcaagc
    11401 gcatcattca agataacaga tgtatctatc acgtatttct tgatttgttg accatattcg
    11461 taatattctt caaaaatatc atcgaaaaca atcgctttac tgtcatacaa tttttcaaaa
    11521 agacgattct tttcagcaag gttacgttct aaacgctcac ggaaaatatc tttatctaaa
    11581 agatctgcaa tacgaattcc aacacgagca gccttgtcca tataagctgg accaattccc
    11641 ttaattgtcg taccaatctt attgtcgccc ttagcttctt cttgcaagcg atccaactcg
    11701 atatgataag gcaaaataac atgcgcacga tcagaaatac gcaagttatc agttgttaca
    11761 ccttcctcat gaagatagct caactctttt acaagagatt taggatttac aaccatacca
    11821 ttcccaatga cagatatttt ttcagggaag aaaatcccag atggaatcaa gtgcaactta
    11881 aatttcttac cgtcaatcac aatcgtgtga ccagcattat caccaccttg gtaacgtgca
    11941 atcacttctg cattcgctga aaggaagtct gtaatcttcc ctttaccttc atcaccccat
    12001 tgggtaccta caacaacaac tgaagtcata attttgtctg agccctcagg ctcttccttt
    12061 ctcacataca tggcaggact ctcacctgca attatatctt acaatttatt ataataaaaa
    12121 atcgcctttt tatcaagaag aaacaataga aagatttgct atttccaact attaaaaaat
    12181 gatttagaaa aattactagc tatttactat tatctttaca taaaagagta aattagttcg
    12241 gaaatttact aaaattacct caacaagaaa taaaaccccg attcattacc aatttttcaa
    12301 gatacaaacg ataagcaaca cgataatggt aaacgataaa atccctatga caaccaatgc
    12361 catatctcac taaataataa attaaaaatt taaaatgaac atgttcccag tcaaaattat
    12421 taccaaatgt aggaccatac tcttcttcaa tactatcata gaaattagcc atctgctcat
    12481 aaattttttg taacataatc aaatactcct tttctttttt ataaacttat tctaacaaaa
    12541 aattttacac attcactatc aattcctgaa ttgttaaaat accagcctca acaagataaa
    12601 aataggaaaa gttgacaaaa tagaaacaaa tttgctacct aaatttcaaa caattaaagt
    12661 tctaaaaaga ccgccttaaa acttttgggt aaatcctatt agaactataa tatttttata
    12721 taggtattat ggttctgatt ttctagtata aaaaaattca aactagaatt cttcttagaa
    12781 aaggccgttt taagtgctat cattgctcaa aaatggaggt tgctgagact tctatcgtca
    12841 agaagaatca tcaaattcct tgtatcatca accaaaagat tgctcagaag ctaattgaaa
    12901 agacttctat gaccgacatt gatcatcagt tgtctatttc aacttcaact gtcattcgca
    12961 agatcaatga ttttcacttt gagcatgatt tttcgcgtct tcctgagatt atgtcctagg
    13021 acgttgaaac agtctgggga gtgactgttt caatcgggag atagagatga gctttattgc
    13081 tcaggacttt gataagctca atatcataac tgttcttgag agcagaacac aagccatcat
    13141 ccgaaatccc atgaatacaa ggctatcaag cgatactgaa agctcattca acaagatagt
    13201 cagaaactga gtgataaaga aattctagat aaacttttga gctattccga agacttgaaa
    13261 caccactata atctctatca gctcttgctt ttccacctct ttttcagact ctgtttaaaa
    13321 ccttcctcaa agataaagag aaaatcgtca acgcccttca attaccttat tccaacgcca
    13381 aactggaagc caccaataat ctcatcaaac ttatcaagca caatgccttt ggttttagga
    13441 actttgaaaa cttcaaaaaa gaaaggacga aatttgtcct ttctagatct tcgctttctt
    13501 caacccacta cagttgacaa agaaccgaaa aatgtctcgc ctctaatata gtcaattgaa
    13561 acaagaacaa gacaaaagag cctcgtaaaa ggtattgcaa cttggtaata cctttttgag
    13621 gtgctttttg atatgagccc atgttttctc aataggattg tactcaggtg agtagggagg
    13681 aagatgtaaa agtttatgcc caaactcttc gcataaaagt tctagcttcc ccattctgtg
    13741 gaatcttgca ttgtccataa tatagtagat tgaaactaga atagtacacc tctacttcta
    13801 aaacattgtt agaattcgat tttactgtcc taatcgattt gtcctattct tatttcattt
    13861 tactataaca cgaaatagat tattattaca taacaaaaaa gaggtctaaa cctcttaact
    13921 caattactcc gccagtagga ctcgaaccta cgacatcatg attaacagtc atgcgctact
    13981 accaactgag ctatggcgga tta
//
LOCUS       DAVMBH010000047        13929 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVMBH010000047 DAVMBH010000000
VERSION     DAVMBH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.047"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..90
                     /locus_tag="VYP30_001689"
     CDS             <1..90
                     /locus_tag="VYP30_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV1808645.1"
                     /translation="FSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            281..2572
                     /gene="pcrA"
                     /locus_tag="VYP30_001690"
     CDS             281..2572
                     /gene="pcrA"
                     /locus_tag="VYP30_001690"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1808646.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2615..3295
                     /gene="radC"
                     /locus_tag="VYP30_001691"
     CDS             2615..3295
                     /gene="radC"
                     /locus_tag="VYP30_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1808647.1"
                     /translation="MYSISFQEDSLLPREKLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3292..3981)
                     /locus_tag="VYP30_001692"
     CDS             complement(3292..3981)
                     /locus_tag="VYP30_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1808648.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(3999..4640)
                     /locus_tag="VYP30_001693"
     CDS             complement(3999..4640)
                     /locus_tag="VYP30_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1808649.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4723..4938)
                     /locus_tag="VYP30_001694"
     CDS             complement(4723..4938)
                     /locus_tag="VYP30_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1808650.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(4946..5293)
                     /locus_tag="VYP30_001695"
     CDS             complement(4946..5293)
                     /locus_tag="VYP30_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1808651.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5298..6413)
                     /locus_tag="VYP30_001696"
     CDS             complement(5298..6413)
                     /locus_tag="VYP30_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1808652.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6423..7382)
                     /locus_tag="VYP30_001697"
     CDS             complement(6423..7382)
                     /locus_tag="VYP30_001697"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1808653.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7495..8064)
                     /locus_tag="VYP30_001698"
     CDS             complement(7495..8064)
                     /locus_tag="VYP30_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1808654.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8192..8863
                     /locus_tag="VYP30_001699"
     CDS             8192..8863
                     /locus_tag="VYP30_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1808655.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8847..9665
                     /locus_tag="VYP30_001700"
     CDS             8847..9665
                     /locus_tag="VYP30_001700"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1808656.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9662..10558
                     /locus_tag="VYP30_001701"
     CDS             9662..10558
                     /locus_tag="VYP30_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1808657.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10602..11576
                     /gene="pta"
                     /locus_tag="VYP30_001702"
     CDS             10602..11576
                     /gene="pta"
                     /locus_tag="VYP30_001702"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1808658.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11838..13164)
                     /locus_tag="VYP30_001703"
                     /pseudo
     CDS             complement(11838..13164)
                     /locus_tag="VYP30_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(13345..13644)
                     /locus_tag="VYP30_001704"
     CDS             complement(13345..13644)
                     /locus_tag="VYP30_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1808659.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         4052 a         2616 c         2975 g         4286 t
ORIGIN      
        1 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct
       61 ggtattatca atcatgaact aggattctag ttttgcagga agtctattga ggtattgagc
      121 tagtttatga aaaaattggg tgaaaagtcg agtgttttag aaacccacag tgtagtattc
      181 tagtttcaat ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg
      241 atataataga aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg
      301 aatgaatgac cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc
      361 aggggctggt tctggaaaga ctcgtgtttt gacccaccgt atcgcttatt tgattgatga
      421 aaagctggtc aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga
      481 gatgaaagag cgtgcttata gcctcaatcc agcgactcag gactgtctga ttgcgacctt
      541 ccactccatg tgtgtgcgta ttttgcgtcg cgatgcggac catattggct acaatcgtaa
      601 ttttacaatt gtggatcctg gtgaacagcg aacgctcatg aaacgtattc tcaaacagtt
      661 gaacttggac cctaaaaaat ggaatgaacg aactattttg gggaccattt ccaatgctaa
      721 gaatgatttg attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat
      781 tgtggcccag tgttatacag cctatcaaaa agaacttcgt cagtctgaat ccgttgactt
      841 tgatgatttg attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta
      901 ctaccagcaa aaattccaat acatccacgt tgatgagtac caagatacca accacgctca
      961 gtaccaattg gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc
     1021 ggaccagtct atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa
     1081 ggattacccc aaagccaagg ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat
     1141 tctccaagcg gccaacgagg ttattaaaaa taataaaaat cgccgtccta aaaatctctg
     1201 gactcaaaac gctgatgggg agcaaatcgt ttactatcgt gccgatgatg agctggatga
     1261 ggctgtattt gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa
     1321 ggattttgca gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct
     1381 caagtctaac attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat
     1441 tcgcgatatt attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga
     1501 gcgtattatc aacgagccta aacgtggaat tggtttaggt acagttgaga aaatccgtga
     1561 ttttgcaaat ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg
     1621 tatcaagggt aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg
     1681 ggagcagcta gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg
     1741 ttatgtcgat attcttaacg cccaagcgac tctagaaagc aaggcacggg ttgaaaatat
     1801 cgaagagttt ctttctgtta cgaagaactt tgatgacacc acggatgtga cagaagagga
     1861 aactggtctg gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga
     1921 ttcaggtagt caggagacat cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct
     1981 cgaatttcca gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc
     2041 gactgaagat tcagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg
     2101 tgcagagaaa attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa
     2161 ttataaccgt ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg
     2221 tctggctcgt cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt
     2281 tggtcaaggt atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa
     2341 atcaatccag tcaagcggtc ttccatttgg tcaatttaca gctggcgcaa aaccagcatc
     2401 tagcgaggca aattggtcca ttggtgatat tgctctccac aagaaatggg gagagggaac
     2461 cgttctggaa gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt
     2521 aggtttgaaa aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat
     2581 ccttctcacg aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga
     2641 ttcactatta ccaagagaaa agctggccaa ggaaggagtt gaagcgctta gtaaccaaga
     2701 gttgctagct attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca
     2761 aaaagtcttg aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt
     2821 gcagagtttg tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact
     2881 ggggcatcgt attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa
     2941 gttggccaag aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact
     3001 ctatctcaat actcaaaatc aaatcatcca tcagcagacc atttttatcg ggtctgtaac
     3061 tcgtagtatc gctgaaccgc gagagattct tcactatgca atcaagcata tggcgacttc
     3121 tcttatcttg gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca
     3181 tgtcactaaa cttgttaaag aagcctgcga attgatgggg attgttctct tggaccattt
     3241 gattgtctct cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc
     3301 attaacgaca tagtcaaaga gttttttatc tttgggacga ttttcaaaaa gaagttctgg
     3361 atgccattgg acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc
     3421 atctttagga tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg
     3481 gtggaaggag ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc
     3541 tgttaccaag cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc
     3601 ttggtacaaa gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa
     3661 aatgggcttt ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg
     3721 aaggtgatag tcatcactat caatggtttt gggttcgcca taaaattttg gatcgacatt
     3781 ttgcccacct gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg
     3841 atcaccaatc ggtaggatga tgggaatccc tccagcatct ttaacgcctt caacaaagcc
     3901 ttttgctgcg tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat
     3961 cccaataact ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag
     4021 tagaggaggg tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt
     4081 aaatgcagat ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga
     4141 ttagcaacct cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca
     4201 tctttgattt tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg
     4261 gtaccgactt caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt
     4321 tcgtggaagc ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca
     4381 ttggtaatag agttgtcatt gagcaaatcg gcaaaaaatg tcattagttt tttgacatca
     4441 tagccaaaac cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtcgct
     4501 gaatcaatac cgatagcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca
     4561 tgaaatctct taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata
     4621 gcaaactgtt tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat
     4681 tgtgaaaaaa tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa
     4741 atctgcatga gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc
     4801 cctaaaagtc agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt
     4861 caacatgaga gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt
     4921 ataggtcagt tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta
     4981 ccaagctatc catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga
     5041 aaatatcaac tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt
     5101 ccttgttaat gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa
     5161 ggcgagtcag ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga
     5221 attttttaac agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt
     5281 tttcaaatgc catatggcta acctccgata atttctttta aggtttttgc gagggtttgt
     5341 aggtcttcaa cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct
     5401 gaatttgcgc catacatggc tttaagaaca tggctggatt ggacaacgcc tgcagtacag
     5461 gctgagccag tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt
     5521 ttctgaccag gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag
     5581 taatactgaa tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga
     5641 aaatgttctt cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatggca
     5701 ggcagatttt cagttcctgc acgttttttc tgttcctgat ctccgccatg tagataggaa
     5761 tcaaagtcca tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg
     5821 gcagaagcag tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata
     5881 gcctgaactg catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca
     5941 gcgatgggaa gtaggtttcc tgtctcatta ttggcaaaca tagtagaaac caaaatcgta
     6001 tcgtcacgta aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata
     6061 atggttgctt caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg
     6121 tgctcgatgg cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca
     6181 atgatggtag tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt
     6241 gtccttagta actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga
     6301 ccatgaccat gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct
     6361 gaaatagcaa ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca
     6421 ccttatttct ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg
     6481 acgatagcat caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt
     6541 tcttttgttg ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc
     6601 tcagcagctc cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct
     6661 tcacgttcaa cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca
     6721 atcaagatag ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca
     6781 tcgtcttgag ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc
     6841 gcacgtttga cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct
     6901 ttatcgcagt aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca
     6961 aagaaacctt gaacctgaac ggcatgcaaa tcaagagtca ggatacgatc aactccagcc
     7021 ttaaccagca tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg
     7081 tcttgacgtg catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc
     7141 acacaagcat cgaccatgat taacaattcc attaggtggt tgttgacagg gaaacttgtt
     7201 gattggatga tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct
     7261 ccgtctgaaa attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt
     7321 ttttgtgcaa tctcttggtt agagttgagt gcgaaaagtt tcatgttttt tctatctgac
     7381 attatagacc gtcctctgta aactttataa atcctagtta tatttacctt acatatatga
     7441 actggggttt gtgtattttt atcttttcta ttttaccaaa aaatggagat tatttcagct
     7501 atttttcata cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg
     7561 atttttctct aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag
     7621 ctccaattcg taatctgtca tatcaaagta tcggctctga tccagtgcca tgagaccaat
     7681 agctgttttc atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact
     7741 ttggatacca tgtttcgcca attcatccag tactagccct tgaggaagtt cttccttact
     7801 cagatagttc tcagcatctt ttagttgcaa tttttggttg tattccatgt ttccaacact
     7861 ctgcgggact ttgagtgtca actcagccca gtcttcaaag gttcgaatgc gcatagcgac
     7921 tttcttttct cgcagttcaa aatcaggcgt gtcgatgtag taatttgttt gaagaacagg
     7981 agtgacacct gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt
     8041 caattcaatt tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta
     8101 tggtataata agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt
     8161 tgacggataa tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga
     8221 tccttacatt caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata
     8281 tcgtaagcaa aataagcatt ctccaattga gtttgtgacc ggtcgagtca agccaattga
     8341 gagcatcaaa gaaaaaatgg ctcgtcgtgg cattacttat gcgaccttgg aacacgattt
     8401 gcaggatatt gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt
     8461 ggatattttg cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca
     8521 tagaaaagca tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat
     8581 caatggagct aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg
     8641 ggcaacgata gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa
     8701 gaagcgactg gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat
     8761 tcgtgatgat atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga
     8821 cggtgtagga aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag
     8881 ccaatagaaa accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa
     8941 atcagtttat actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta
     9001 tgctcttgtc ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc
     9061 ttcatactgg acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag
     9121 tgactaattt gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg
     9181 tctttcttga aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca
     9241 ggtctgatcg aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc
     9301 gtggagacgg gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg
     9361 gcggtgctgt tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta
     9421 ataatcgtgt ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg
     9481 aacttattcc aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt
     9541 tccgtaatat tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga
     9601 ctcctagcca taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg
     9661 aatgaggttt gaatttatcg cagatgaaca tgtcaaggtt aagacctttt taaaaaagca
     9721 cgaggtttct aagggattgc tggccaagat taagtttcga ggtggagcta ttctggtcaa
     9781 taatcaaccg caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat
     9841 tcccgctgag gaaggctttg aaaccttgga ggctattgag catccattag atattctcta
     9901 tgaggatgac cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt
     9961 caatcactct aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga
    10021 aaatcagcag gttcacattg ttaccagact agatagggac acttctggct tgatgctctt
    10081 tgccaagcac ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga
    10141 gaaacgctac tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat
    10201 tgctccgatt gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcggaaa
    10261 gtatgcccat acttcataca agattgtagc ttcttatgga aatattcact tggtctatat
    10321 tcacctgcac actggtcgaa cccatcaaat ccgagtccat ttttctcata tcggttttcc
    10381 tttgctggga gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct
    10441 gcattgccat tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag
    10501 tcccttgccg gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa
    10561 actgtctcag agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc
    10621 tcaaagccaa ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc
    10681 gtattcttca agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg
    10741 gaaatcctga aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg
    10801 tcatcgaccc tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc
    10861 gcaagggcaa aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact
    10921 ttggtgtgat gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact
    10981 caacagcttc aacagttcgc ccagctctac aaatcatcaa aactcgtcca aatgtaactc
    11041 gtacttcagg agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg
    11101 ccattaatat caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca
    11161 cagctaagat gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggtt
    11221 cagggtttgg tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc
    11281 gtcctgacct tgaaatcgat ggtgagttgc aatttgatgc ggcctttgtt cccgaaactg
    11341 cagctctgaa agctccggga agtacagtag ctggtcaagc aaatgtcttc atcttcccag
    11401 gtatcgaggc aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg
    11461 taggacctgt tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg
    11521 cagatgatgt ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa
    11581 aactataaag tgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg
    11641 ccattaattc ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat
    11701 gatatcctgt ctatacacga cctatagaaa tctgtaatat acatatccgt aaaacgataa
    11761 attccctttt tgattttaaa tgagtatgaa aagagaattt tttggctctt tgtcaactgt
    11821 agtgggttga agaaaagcta agctcgagaa aggacaaatt tcatcctttc ttttttgata
    11881 ttcagagcga taaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg
    11941 cgcttgataa gtttgatgag attattggtc gcttccagtt tggcgttaga atagtgtagt
    12001 tgaagggcgt tgataatctt ttctttatct ttgaggaagg ttttaaagac agtctgaaaa
    12061 ataggatgaa cctgcttaag attgtcctca ataagtccga aaaatttctc tggttcctta
    12121 ttctggaagt gaaaaagcaa gagttgatag agctgatagt ggtgtttcaa gtcttccgaa
    12181 tagctcaaaa gcttgtttaa aatctcttta ttggttaagt gcatacgaaa aataggacga
    12241 taaaatcgct tatcactcag tttacggcta tcctgttgaa tgagtttcca gtagcgcttg
    12301 atagccttgt attcatggga ttttcgatga aactgattca tgatttggac acgcacacga
    12361 ctcatagcac ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc
    12421 gggagtgaaa cagcctggga gactgtttca gcctgagcct agaaatttga aagcgaagct
    12481 gtttagccaa gtcatagtaa gggctaaaca tatccatagt aatgattttg acgcgacatc
    12541 ggacggctct atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccttcaa
    12601 gaacagtgat gatattgaga ttgttaaaat cttgcgcaat aaagctcatc tccatctccc
    12661 gattgaaaca gtcactcccc ggactgtttc aacgtcccaa gacataatct taggcagatt
    12721 tctaaaatta cactcaaagt ggaagtcatt gagctttcga atgacagttg aagttgagat
    12781 ggaaagctga tgggcaatat cagtcataga aatcttttca attaactttt gagcaatctt
    12841 ttggttgatg atacgaggga tttgatgatt cttcttgacg atagaagttt cagcaaccat
    12901 aattttagaa caatgatagc acttgaaacg acgctttcta aggagaattc tagtaggcat
    12961 accagttgtt tcaagataag gaattttaga aggtttttga aagtaatatt tcttcatttg
    13021 acttccgcac tcaggacaag atggagcttc atagtccagt ttggcgatga tttccttgtg
    13081 tgtatcctta ttgacgatgt ctaaaatctg gatattaggg tctttaatgt ctagtaattt
    13141 tgtgataaaa tgtaattgtt ccatatgatt ctttctaatg agttgttttg tcgcttttca
    13201 ttataggtca tatgggactt ttttctacac aaaaataggc tccataatat ccatagggga
    13261 tttacccact acaaatatta tagagtcatt tttgcacctt tcttagcctt tgttatcgac
    13321 aagcattgtt ctagctcctt gtttttagaa aggtaatttc ccagcgaaag cacccagttt
    13381 tttcttggta gtttcatcga tttgttcaag agcagagttg atggcttgaa cggtcatatc
    13441 agaaagagtc tcaaggtcct ctgggtcaac gacagctgga ttgaaatcaa tgctgacaac
    13501 tttcttatcg ccagttaagg tcgcttggac aagatcttga gcagatttgc caacaaattg
    13561 catagcagca agttcagctt ggctttgttc catttgtttt tgaagttttt gtgcttgacg
    13621 catcatgttt tgcatgttca tcataagatt tctaaagttc ctttcatctc aaggggataa
    13681 tccttgttgt taacaagtgc ctgattttct ctcctaattg ttattagtag catagccatc
    13741 aagcccaagt attgatttta ttataccatt tttttaagac atagtctttt attggtgaga
    13801 gttatttatg tcaaggagtg attagaaata aattaaaata atgatttttg ctaagagggc
    13861 tctattctag tttcatggaa atgattttac taaaggttcg tatgctttgt ttgcaaacat
    13921 gttacatct
//
LOCUS       DAVMBH010000048        13819 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVMBH010000048 DAVMBH010000000
VERSION     DAVMBH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13819
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.048"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(20..2179)
                     /locus_tag="VYP30_001705"
     CDS             complement(20..2179)
                     /locus_tag="VYP30_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV1808660.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(2176..2772)
                     /gene="recU"
                     /locus_tag="VYP30_001706"
     CDS             complement(2176..2772)
                     /gene="recU"
                     /locus_tag="VYP30_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1808661.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            2838..3365
                     /locus_tag="VYP30_001707"
     CDS             2838..3365
                     /locus_tag="VYP30_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1808662.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            3435..3764
                     /gene="gpsB"
                     /locus_tag="VYP30_001708"
     CDS             3435..3764
                     /gene="gpsB"
                     /locus_tag="VYP30_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1808663.1"
                     /translation="MASIIFSAKDIFDQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            3785..4165
                     /gene="rnpB"
                     /locus_tag="VYP30_001709"
     ncRNA           3785..4165
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYP30_001709"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4250..5407
                     /locus_tag="VYP30_001710"
     CDS             4250..5407
                     /locus_tag="VYP30_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1808664.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQIENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            5420..6814
                     /gene="mapZ"
                     /locus_tag="VYP30_001711"
     CDS             5420..6814
                     /gene="mapZ"
                     /locus_tag="VYP30_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1808665.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVEIQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDANAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            6890..8314
                     /gene="gndA"
                     /locus_tag="VYP30_001712"
     CDS             6890..8314
                     /gene="gndA"
                     /locus_tag="VYP30_001712"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1808666.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPATFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            8326..9015
                     /locus_tag="VYP30_001713"
     CDS             8326..9015
                     /locus_tag="VYP30_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808667.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            9113..10135
                     /gene="cbpC"
                     /locus_tag="VYP30_001714"
     CDS             9113..10135
                     /gene="cbpC"
                     /locus_tag="VYP30_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1808668.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQNLGNNWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            10154..11152
                     /gene="cbpJ"
                     /locus_tag="VYP30_001715"
     CDS             10154..11152
                     /gene="cbpJ"
                     /locus_tag="VYP30_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV1808669.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKDSTIGPYPNGMRLEGFPNS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNRWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLCSSGAMVTGW
                     VKDDSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(11270..12502)
                     /locus_tag="VYP30_001716"
     CDS             complement(11270..12502)
                     /locus_tag="VYP30_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1808670.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEISHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLLLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(12545..13507)
                     /locus_tag="VYP30_001717"
     CDS             complement(12545..13507)
                     /locus_tag="VYP30_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1808671.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT         4203 a         2367 c         3146 g         4103 t
ORIGIN      
        1 aaaatctggg tgataaatgt tatggttgtg ctggttgagg attctgattt tgttgatcag
       61 gggttgtatt tgattgttgc gtattattgt taggattggt agtcgtacta ttatttgtgc
      121 ttggagtggt tgagctagac tgtgaagttg aactatctga tgatgagctt gaactttcag
      181 ttgatggggg ttgttgtgga gcaggtgagt tccacgtaga acgagcacca tttttaaata
      241 cgaattctcc atttctgtag agcccctctg gtatattcca atcttctgga ttgcttcctt
      301 cagacaggta ggtcatcata gagcggtaaa ctttggcagc gaccgtaagg ccattgccta
      361 caagtggtgt cagacggtta gaatagcctg tccatacagc cattgaatat ttacgcgtat
      421 agccagcaaa tagttcatca ggtgctacaa attgagaggt cttgatgtgg ttttcaattt
      481 cctcgtctgt atagttagag gttcctgttt taccagcctg aggaagccaa gcaagatagg
      541 catttcgtcc agttccataa gtcaagactg ttttcatcat gtcggtcatc atataggctg
      601 tcgtttcttt catggcacga gttccgacat tagagaactc tttttcactc ccatcactaa
      661 agacgacttt atggatatac attggtttat agtaagttcc accatttgca aaggcagcgt
      721 aagcagcagc catcttttca ctacttgctc catatttttt gtctgattcg gttgtgttac
      781 ttgaaatggc atttgagtag tgaatacttg ggtagtcgat tccgagacca tttaggaaag
      841 tcttggcgcg gttgagtccg accttgttta gagtttccac ggctgggacg tttcgcgatt
      901 gttgcagggc gtattgcaag gtgatgttgc caaagtagcc cctatcccag ttataaacag
      961 gagtatttgt cccagggtaa ttatagggct catcgtgaac gatagtagca gttgaatcgt
     1021 agacaccgta ctccaaggca ggagcatagt ctgtgatcgg tttcatagtt gatccccagt
     1081 cgcggtttgt ttctactgct tggttaattc cgaaggaaac attacttgac tgatggcgtg
     1141 ctcctagctg ggcaatgact ttaccgttag aaacatcaac aatggtagaa gcgacttgca
     1201 attcatcgtc tggataggca acgtattcgt ctgtattgta aatatcccac agatgttttt
     1261 gagcttcttg gtctacattt gtgtagacat ccatcccagt tgtgagcagg ttatagcctg
     1321 tttcttcttc aacttgattg atgacttcct tgaggtaatt atccatgtaa gcagggtaat
     1381 tacttgctga tttgagactt tgtagtccat cagtaattgg tgtattgact gctttctcat
     1441 actgttcagc agagatgtag ccttgatttt tcatttcaga taagaccaag tttcggcggt
     1501 cttgggctgc ttctggatgt gaataggggt catattggtt tggtgcctga ggcattccag
     1561 ccagcaaggc taactgaggt aaacttaaat tattgaggtc tttaccatag tagttttgag
     1621 ctgctgtctg cattccatag ttcccattag acatgtagac cttatttata tagtaggtca
     1681 agatttcttg cttggttgct ttttgttcta actgaatcgc taaccaagct tcctgagcct
     1741 tacgagaaat agtctggtcg gaagtcgaag ttgaaaagta agtcaactta atcaactgtt
     1801 gggtgagagt tgatccacct tggagggaat tgctttgcag attgcgcaag aaagctccca
     1861 ggatacggat ggtatcaatc cccctgtggt cgaagaagcg atggtcttcg atagaaacga
     1921 ttgccttaac caaatctgtg ggaatatcat tagcttgggc attgacgcgg cgttcagaac
     1981 ccaagtcagc aatgagttga tttttattgt cgtagatttt actagaagtt gttgcaacta
     2041 gtttactctc ggataggcta ggagccttgc taacgtagta gaaaaaaact cctccgccta
     2101 agacaatggc tgcgataacc aagcttaaga agctaatgct cagatacttg attaggcgca
     2161 gaatcgttgg tttgttcatc ttgttttacc acctaataaa tgttctttga taacattgag
     2221 ataaggaatt tgagggaagg caccagcctt gatttcatat ccatattctc gaatatattc
     2281 aagtggcatt gatttttgtc ccttatcttg atgatagaag cgaatcaaat cgaatgccgg
     2341 caataagtag gtttcttgct gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg
     2401 ggcaaggact tgttccatat gctgaatctg atgtggatga aaatttttca tcggaatcgc
     2461 acgtttttgt tttgtttcct tgacttcaaa gtcgatgtaa tatccattat aaacgccaga
     2521 atagtccgtc gttgaagctt gtcgaaaata ggcttcaaca atcttggcac gacttcgttg
     2581 tggatagtcc acttgtacga tttgaatagg agttggtttc ttatgtataa cagccaagcc
     2641 ctgagacaaa tagtagtcgt tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt
     2701 tgcgaaattt ttgggttgag aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg
     2761 atagttgacc ataattctcc ttattggtac aataacatca ctttattata ccataatttg
     2821 cacagaaagg gttaaaaatg gctacagctt tggttttagg ctattctgct tttgatttgg
     2881 gtttattttc tgataaggat cctcgtctta aattgattaa aaaagcgata cgtaaagatt
     2941 tagaggctat ggcagcagat ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg
     3001 aatattgggt tttagaggtt gctcaggaga tgaaaaccga atacggtttc cagttggcca
     3061 ccatttttgc ttttgaaacc catggggaaa attggaatga aggcaatcag atgaaactga
     3121 gtcgctttaa gcaggtagac tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc
     3181 agttaagaga ttaccagcag tttttgctgg aaaacacgac tagttcctat cttttttatg
     3241 atgaagaaaa tgaaacaaaa ctagcttatt tttaccaaaa gatgaaaaat caagaggact
     3301 attttataaa gagattaaca tttgatcaat taaatgaact tgctgaaaat ttttccgaaa
     3361 attgaagctt tgaccttgat ttttgtttgc ctttttttat ataataatac tagcaagcga
     3421 gaatggagag agacatggca agtattattt tttcagcgaa agatattttt gatcaagagt
     3481 ttggacgtga agtccgtggc tataataaag tagaagttga cgagttttta gacgatgtca
     3541 tcaaggacta tgaaacctat gctgccttgg tcaagtcact tcgtcaggaa attgcggatt
     3601 tgaaggaaga attaactcgt aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag
     3661 cggcaattac aagttctatg acgaattttg atattttgaa acgcctgaat agattggaaa
     3721 aagaagtttt tggtaaacaa attttagata actcagattt ttaagtagtt atttgagatg
     3781 tgcaattttt ggataatcgc gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc
     3841 acaggctgtg atgcctgtag tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa
     3901 tcgttacggc agttgaaatg gctaagtcct tggataagcc agagtaggct tgaaagtgcc
     3961 acagtgacgg agtctttctg gaaacagaga gagtggaacg cggtaaaccc ctcaagctag
     4021 caacccaaat tttggtcggg gcatggagta cgcggaaacg aacgtagtat tctgactgct
     4081 atcagttaga gctgttagtg gtagacagat gattatcgaa ggaagtggtc ctagtcactt
     4141 ctggaacaaa acatggctta tagaaaattg catataggtt ggggctgaga aattttctca
     4201 acctcatttt ttaaagtgga catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga
     4261 atttaattta attgcaactg tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg
     4321 agagttgggc tacgattgtc agattgaaaa tggacgtgtt cgttttcaag gagacgtgag
     4381 agctattatc gaaaccaacc tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg
     4441 aacgttccct gctaagactt ttgaagagct atttcaggga gttttcgctt tagattggga
     4501 aaattattta ccacttggag ctcggttccc gatttcaaaa gctaaatgtg ttaagtccaa
     4561 acttcacaat gagcccagtg ttcaggctat ttctaagaaa gctgttgtca agaaattgca
     4621 gaaacactat gctcgcccag aaggggttcc tctgatggag aatggcccag agtttaagat
     4681 tgaggtctct attctcaaag atgtggcaac tgtcatgatt gatacgaccg ggtctagcct
     4741 ctttaaacgt ggttatcgta ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc
     4801 agccatttta caactttcta actggtatcc agacaagcct ttgattgatc cgacctgtgg
     4861 ttcggggact ttctgtattg aggcagttat gattgctaga aagatggcgc caggtcttcg
     4921 tcgctctttt gcatttgagg aatggaactg gatcagcgat cgcttgattc aagaagtgcg
     4981 cacagaagcg gctaaaaaag tagaacgtga gcttgagctg gatatcatgg gctgtgatat
     5041 tgatgctcgc atggtggaaa ttgctaaggc caatgctcag gtggctggtg ttgcaggaga
     5101 cattactttt aagcagatgc gcgtgcagga tttacgttcc gataaaatca atggagtaat
     5161 catttccaat ccgccttatg gtgaacgttt gtcagatgat gcaggggtga ccaagctcta
     5221 tgctgagatg gggcaagtat ttgcaccgct gaaaacttgg agcaaattta tcctgactag
     5281 tgatgaagct tttgaaagca agtatggtag ccaagcagat aagaagcgta agttatacaa
     5341 cggaaccttg aaagtggatc tgtatcaata ttttggtcag cgtgtcaaac ggcaagaggt
     5401 aaaatagaaa gggatactca tgagtaaaaa aagacgaaat cgtcaaaaaa aagaaggtca
     5461 agaaccgcaa tttgattttg atgaagcaaa agagctaaca gttggtcaag ctattcgtaa
     5521 aaatgaagaa gtggaagcag gagtcttgcc tgaggattcc attttggaca agtatgttaa
     5581 gcaacacaga gatgaaattg aggcggataa gtttgcgact cgtcaataca aaaaagagga
     5641 gttcgttgaa attcagagtc tggatgattt aattcaagag atgcgtgagg ctgtagagaa
     5701 gtcagaagct tcttcggagg aagttccatc ttctgaagac atcttactac ccttgcctct
     5761 ggacgatgag gagcaaggct tggatcctct attgctagat gatgaaaatc caacagaaat
     5821 gactgaagaa gtggaagagg agcaaaacct ttctcgtctg gatcaagagg actcagaaaa
     5881 gaaaagtaaa aaaggcttta ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt
     5941 cagtgcttat tatgtctacc gtcaagtggc tcgttcgacc aaggaaattg aaacttctca
     6001 atcaactaca gccaatcaat cggatgtgga tgattttaat acactttatg acgcctttta
     6061 cacagatagc aataaaacgg ctttgaaaaa tagccagttt gataaactga atcaactcaa
     6121 gactttactt gataagctgg aaggtagtcg tgaacatacg cttgccaaat ctaaatatga
     6181 tagtctagca acgcaaatca aggctattca agatgtcaat gctcaatttg agaaaccagc
     6241 tattgtggat ggtgtgttgg atgccaatgc caaagccaaa tcggatgcta aatttacgga
     6301 tattaaaact ggaaatacgg agcttgataa agtgctagat aaggctatca gtcttggtaa
     6361 gagccagcaa acaagtactt ctagctcaag ttcaagtcaa actagcagct caagttcaag
     6421 tcaagcaagc tcaaatacga caagtgagcc aaaaccaagt agttcaaatg agactagaag
     6481 tagtcgcagt gaagtcaata tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc
     6541 cagtcgtgtt gcctataatc agtctgctat tgatgatagt aataactctg cctgggattt
     6601 tgcggatggt gtcttagaac aaattctagc gacttcacgt tcacgtggct atatcactgg
     6661 agaccaatat atccttgaac gtgtcaatat cgttaacggc aatggttatt acaacctcta
     6721 caagccagat ggaacctatc tctttaccct taactgtaag acaggctact ttgtcggaaa
     6781 tggcgctggt catgcggatg acttggacta ctaagcagtc gttacaaaat tctttctttt
     6841 caaaagtaaa aatgataaaa taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc
     6901 taactttggt gtcgtaggta tggccgtaat gggtcgtaac cttgccctta atattgaatc
     6961 tcgtggttac acagttgcta tctacaaccg tagtaaagaa aaaacggaag atgtgattgc
     7021 ttgccatcct gaaaagaact ttgtaccaag ctatgacgtt gaaagttttg taaactcaat
     7081 cgaaaaacct cgtcgtatca tgctgatggt tcaagctgga cctggtacag atgctactat
     7141 ccaagccctt cttccacacc ttgacaaggg tgatatcttg attgacggag gaaatacttt
     7201 ctacaaagat accatccgtc gtaatgaaga attggcaaac tctggtatca actttatcgg
     7261 tactggggtt tctggtggtg aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg
     7321 acaaaaagaa gcctacgaat tggttgcgga tgttcttgaa gaaatctcag ctaaagcacc
     7381 agaagatggc aaaccatgtg tgacttacat cggtcctgat ggagctggtc actatgtgaa
     7441 aatggttcac aatggtattg agtacggtga tatgcaattg atcgcagaaa gctatgactt
     7501 gatgcaacac ttgctaggcc tttctgcaga agatatggct gaaatcttta ctgagtggaa
     7561 caagggtgaa ttagacagct acttgattga aatcacagct gatatcttga gccgtaaaga
     7621 cgatgaaggc caagatggac caatcgtaga ctacatcctt gatgctgcag gtaacaaggg
     7681 aactggtaaa tggacgagcc aatcatctct tgaccttggt gtaccattgt cactgattac
     7741 tgagtcagtg tttgcacgct acatttcaac ttacaaagaa gaacgtgtac atgctagcaa
     7801 ggtgcttcca aaaccagcta ccttcaactt tgaaggagac aaggctgaat tgattgaaaa
     7861 aatccgtcaa gccctttact tctcaaaaat catttcatac gcacaaggat ttgctcaatt
     7921 gcgtgtagcc tctaaagaaa acaactggaa cttgccattt gcagatatcg catctatctg
     7981 gcgtgatggc tgtatcatcc gttctcgttt cttgcaaaag attacagatg cttacaaccg
     8041 cgatgcagat cttgccaacc ttcttttgga cgagtacttc ttggatgtta ctgctaagta
     8101 tcaacaagca gtgcgtgata tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac
     8161 tttctcagca gctattactt actttgatag ctaccgttca gctgaccttc cagctaactt
     8221 gatccaagca caacgtgact actttggtgc tcacacttac caacgtaaag acaaagaagg
     8281 aaccttccac tactcttggt atgacgaaaa ataagtaggt cagccatggg gaaacggatt
     8341 ttattacttg agaaagaacg aaatctagct cattttttaa gtttggaact ccagaaagag
     8401 cagtatcggg ttgatctggt agaggagggg caaaaagccc tctccatggc tcttcagaca
     8461 gactatgatt tgatgttatt gaacgttaat ctgggagata tgatggctca ggattttgca
     8521 gaaaaattga gtcgaactaa acctgcctca gtcatcatga ttttagatca ttgggaagac
     8581 ttgcaagaag agctggaagt tgttcagcgt tttgcagttt catacattta taagccagtc
     8641 cttatcgaaa atctggtagc gcgtatttcg gcgatcttcc gaggtcggga cttcattgat
     8701 caacactgca gtctgatgaa agttccaagg acctaccgca atcttaggat agatgttgaa
     8761 catcacacgg tttatcgtgg tgaagagatg attgctctga cccgccgtga gtatgacctt
     8821 ttggcgacac ttatgggaag caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt
     8881 tggaagtatg aaagtgcgac cgagacaaat atcgtagatg tctatatccg ctatctacgg
     8941 agcaagcttg atgttaaagg ccaaaaaagc tacattaaaa ccgtgcgtgg tgttggatat
     9001 accatgcaag aatagataag cagttgcagt tgtgtaactg cttttttgag gagtttttat
     9061 atattgacat gcagtcgggt ctttgctaca atcgttttag gaggatatat agatgaaact
     9121 tttgaaaaaa atgatgcaag ttctactagc agtctttttc tttggtttgc tagctacaaa
     9181 tacggtattt gcgaatacca caggtggccg atttgttgat aaggataata gaaaatatta
     9241 tgtaaaagat gatcataaag caatctattg gcataaaata gacggtaaaa cttactattt
     9301 tggtgatatt ggagagatgg ttgtcggttg gcaatactta gaaattcctg gaacaggtta
     9361 tcgtgataat ttattcgata accaaccagt taatgaaatt ggccttcagg agaagtggta
     9421 ctattttgga caagatggtg ctttgctaga acaaacagat aaacaagtac tagaggcaaa
     9481 aacgtctgaa aatacaggaa aagtatacgg tgaacaatat cctctatctg ctgaaaagag
     9541 aacttattat tttgataata attatgctgt aaagacaggc tggatttatg aagagggtca
     9601 ttggtattat ttaaataagc taggaaattt tggcgatgat tcttacaatc cactaccaat
     9661 tggtgaagtt gctaagggtt ggactcaaga ttttcatgtt actattgaca ttgatagaag
     9721 caaacctgct ccatggtact acctagatgc ttcaggtaag atgcttacag attggcaaaa
     9781 agtaaacgga aaatggtatt attttggctc ctctggttct atggcaacag gttggaaata
     9841 tgtacgaggc aaatggtatt acttagataa taaaaatggc gatatgaaaa caggttggca
     9901 aaaccttggg aacaactggt actacctccg ttcatcagga gctatggtaa ctggctggta
     9961 tcaagatggt tcaacttggt actatttaga tgctgaaaat ggtgatatga aaataggttg
    10021 gacaaaagta aatggaaaat ggtattatct caattcctct ggagcaatgg ttacaggtag
    10081 tcaaactatc gatggtaaag tttataactt cgcttcatct ggtgagtgga tttaatgtta
    10141 gaggatatat aaaatgaagc ttttgaaaaa aactatgcaa gctggactaa cagtaatttt
    10201 ctttggtttg ctagctacga atacagtatt tgcagataac tctgaaggat ggcagtttgt
    10261 ccaagaaaac ggtagaacct attacaaaaa gggggacctc aaagaaacct actggcgagt
    10321 gattgatggt aagtactatt attttgattc tctatctgga gagatggttg tcggctggca
    10381 atatatcccg tttccatcta aagatagtac aattggtcct tacccaaatg gtatgagatt
    10441 agaaggtttt ccaaattcag agtggtacta cttcgataaa aatggagtgc tacaagagtt
    10501 tgttggttgg aaaacattag agattaaaac taaagacagt gttggaagaa agtacgggga
    10561 aaaacgtgaa gattcagaag ataaagaaga gaaacgttat tatacgaact attactttaa
    10621 tcaaaatcat tctttagaga caggttggct ttatgatcag tctaactggt attatctagc
    10681 taagacggaa attaatggag aaaactacct tggtggtgaa agacgtgcgg ggtggataaa
    10741 cgatgattca acttggtact atttagatcc aacaactggt attatgcaaa caggttggca
    10801 atatctaggt aatagatggt actacctccg ttcctcagga gcaatggcca ctggctggta
    10861 tcaggaaggt accacttggt attatttaga ccagccaaat ggcgatatga aaacaggttg
    10921 gcaaaacctt gggaacaaat ggtactatct ctgttcgtca ggcgccatgg tgactggctg
    10981 ggtgaaagat gactcaactt ggtattacct aaatgcaggt aatggagaca tgaagacagg
    11041 ttggttccag gtcaatggca gatggtacta cgcttatagc tcaggtgctt tggcagtgaa
    11101 tacgaccgta gatggctatt ctgtcaacta taatggcgaa tgggttcggt aatgacaggg
    11161 cgcttataat tatattagaa cactcgctta atcaaagaag tgactttgtt gtacttgacc
    11221 tgacgattgg ggagattaaa agcatgtgaa atctacacat gctttttcgt tagttatgag
    11281 tgttgaactt gactaaccat tgacaaaaga taagagcaat taaaataaga tacaaaaata
    11341 tcaatgctaa ctgcaccgaa acgcccgatg ctatggatag ggctaatagg gagagcaggg
    11401 acggggcgag aatgtccact gtgctcagag cagagcccac cgtccccatc ttgtcactgg
    11461 ggatatgggc aaagacagct gcttgtaggc gagggctgag aatgccgata atcgtagaac
    11521 tgatgaaact ggtcatgaaa attacgatat aggcttgaca aaggatacta gttattagag
    11581 tcaataggga aatctcacag aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat
    11641 tactgctggt catattgcca aggatagctc cacaagacat gatgatggag agcagggcga
    11701 ggagttgccc aatgctcagt tgtgctagtg tctgttggat gaagcggagg gcaatcagcc
    11761 gaggggacac atccaagatg gcaatcatac tggtcgtcag aagcagtagt atgacggtat
    11821 cttttaacct caggagcaca gccagcgact gtttaagatg ttgaaaatat ttcttaaaac
    11881 tcagtgctgt atgtgatatt tcaattcttt tttcaacctc atacaaggta tgtcgaataa
    11941 catacaggcc caaaaaggca atgacaaaag tcagagtgtt gataagggaa atagtttgaa
    12001 tacttataac attgataagg aatgcgccag ccagattggc gacaatacgg acaaccctca
    12061 tcagagactg cctgaacccc atggcatcat gcaggtcgtc cttaattaca ctgatgtaga
    12121 gggcgttcat catgtaggca gacaggtagc tcaaggtgtc agagatgagg ttgatgatga
    12181 caatcataat gactgaaact aatgaaaagg gcgacaagac gagaaatact gtcaaaatag
    12241 cgtagagcag gattttgatt ttggcaatcc agagtgcgtg tttgactcta ttttcttgaa
    12301 aatctcctag aatcccgaga aagagttgcg atagtagggg aaccatctct gaaatggaaa
    12361 tcagtaaaat cgctagcgga gcgaaattgt actgagccac ataattgata atggcgaggt
    12421 agaaaatact gtcgccgaat gatgaaaaac agctgtttag cagcaactgt ctatatatgt
    12481 tgtttgtcca aaataatttc atacttttct ccttatgtct gcacatcgaa tgggaattta
    12541 ttatttaata gacaccaata taccccatgc ttcctattcc gaagtcaaac aaatctgctt
    12601 taccactatc tccttgaaac atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa
    12661 ttacctgttg gatttttttc atcagtaatt tgttttgatt gtagacagtg gtttgtagta
    12721 agctagttat tccgtggcaa tatcctgtca tcatttttag atgatggtta aaaacaaatt
    12781 cttgatattt actaataata tctttgtttc cgtcacaatc gtacatacaa agatataaga
    12841 ttattccgga aattcctttg caccaagaaa gttgtaaatt tcctaaattt tcagtattag
    12901 aagtaacttt ttctaataat ttttttaatt cagtatggaa tgtatggaga tcattataga
    12961 acatagaagg ttctaagact ttagaatagg caaataaagc atatgcaatt ccacaatatc
    13021 catgagcaaa gctatagtct aaaatgcttt ctttggctgt atctctttgt aggaaataat
    13081 gataaatttc ccctatacta ttgtggatga aaattttaag agtattgtca ttggtaaatt
    13141 gatagtattt tattaatgat aataggacac cagattttcc caatgcaaag tctatttcct
    13201 ctaaagtatc ataattctct attaattttt tagcggtgac gtttgctaat tgtagatagt
    13261 attgattttt actgatagaa aataaatgta ggagtaacca tagatagcct gcatcaccaa
    13321 atagcagtga gtattgatat tcatatgtat gtgtcgttct aattgtcact gccttcttga
    13381 tgatagagag tattttagaa tccagttctg gggggtacaa tttatttaga ggaaacagta
    13441 gtccagctat tccgtgttgg aatgataaat tacttacgaa atttccaaat tctgttgaag
    13501 aagtgatcct tccttcagaa tttacagttt tatctagtaa aaattgtaga acactattac
    13561 attctgtttt gtaatcatat ttatgttcct ctattttttt aattttgact aaattatttg
    13621 tttgacttaa atttagtaga cattgtaacc aaaatagttg ctcatctgtg agctgacctt
    13681 gagtatgtga tagttctagt aattgaatag gatcctttag ttagattcaa tcaatctata
    13741 acacaacaac ataataatac ttttaggata gcttgtcaaa tattatagta aaatgagata
    13801 ataacaggat aaatcgatc
//
LOCUS       DAVMBH010000049        13430 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVMBH010000049 DAVMBH010000000
VERSION     DAVMBH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.049"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(257..1243)
                     /locus_tag="VYP30_001718"
     CDS             complement(257..1243)
                     /locus_tag="VYP30_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1808672.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(1253..2053)
                     /locus_tag="VYP30_001719"
     CDS             complement(1253..2053)
                     /locus_tag="VYP30_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1808673.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(2306..3148)
                     /locus_tag="VYP30_001720"
     CDS             complement(2306..3148)
                     /locus_tag="VYP30_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1808674.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(3150..4442)
                     /locus_tag="VYP30_001721"
     CDS             complement(3150..4442)
                     /locus_tag="VYP30_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1808675.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(4553..5824)
                     /locus_tag="VYP30_001722"
     CDS             complement(4553..5824)
                     /locus_tag="VYP30_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1808676.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            6374..7891
                     /gene="malQ"
                     /locus_tag="VYP30_001723"
     CDS             6374..7891
                     /gene="malQ"
                     /locus_tag="VYP30_001723"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1808677.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVGQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            7917..10175
                     /gene="glgP"
                     /locus_tag="VYP30_001724"
     CDS             7917..10175
                     /gene="glgP"
                     /locus_tag="VYP30_001724"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1808678.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGDENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(11220..11792)
                     /locus_tag="VYP30_001725"
     CDS             complement(11220..11792)
                     /locus_tag="VYP30_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808679.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(12416..13264)
                     /locus_tag="VYP30_001726"
     CDS             complement(12416..13264)
                     /locus_tag="VYP30_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1808680.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
BASE COUNT         4060 a         2456 c         2817 g         4097 t
ORIGIN      
        1 catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct acaacctcaa
       61 aaccatgttt tgagcaacct gcggctagct tcctagtttg cactttgatt ttcattgagt
      121 ataaaaagat cttgggtaac aactcaattt cagtagaaaa ggaagtaaat cttcccacaa
      181 taaaacgcat agtatcaagt tttttcaata cctgatagta tgcgtttttg cttttaacga
      241 ctttttgccc agtctcttat ttttcgataa ttttgtgggc gatcaattga cggtaacaaa
      301 tttgtttatt gtttttatta tcattaataa tctggagaat agtttcaagg gaaacacgac
      361 caagctctaa actattgata tcgacatagg ctgccaagtt gagcttggga ttaaccgagt
      421 caaagctgag aacagggaca tccagctggt gtttggcaat atagttacaa acaccttcag
      481 ctaggaggct atcggttgtg atgatagcat caatttgtgg atcgtgcttg aataatcgct
      541 tgctaaattt atagcccttt tcttccagaa actcgtcggc aaagtagatg cgattgttgt
      601 cagtggtaag tttgtaatgt ttaagcgcct gttcatagcc tgttaaacgg tctttggtca
      661 cgaagagctt tttacttcct ccgataaagg caatgcgttt gcagcctttt ttgatgaaat
      721 attcagtcgc atcaaaacca gcttgaacat tgtcgttgtc gacaagtggg atgaaaggag
      781 atagagattt acctaagata aggaagggga actgttcttc tgcgacgagt tttacgagag
      841 ggtcttcttc ttgggcatag agaaagatta gcccatctac acgcttgccg tagaccattt
      901 gtgaaatagc gttgagacgc tccttctcat ctttccctgt tgctatctga atggcatagt
      961 ggttttcaga tgcgacttga gagatgccac gtagaaccga tggaaagaaa ggattctggt
     1021 agaaggcgtc tgagtcatca ggaagaacta atccgataac ctgagtatag ctgcttacca
     1081 agctacgagc gttgaggttt gggtggtagt tgagttcctt catagctttg cgaacgcgtt
     1141 tttttgtttc gtcgctaatg gttgatttat tttgaataac acgggttacg gttgaaggcg
     1201 aaacaccagc agccttggcc acgtctttaa tcgtaacggg cataaaaatc tcctatttat
     1261 ggtaatttgg atcacggaaa tgtgttttat aaaagatagt gaccagatac agaacaaaaa
     1321 gaatattttg tacagtaatc agggttgtca tattttggcc aaataatccc aaaataagtg
     1381 taatcagagt cggcaatcct aaacagttca agataaagtg atagcactct ttaaaggttc
     1441 taaatgaaaa gaggcgtgat ttcttagtga tataaaggag aagactagct cctagagaga
     1501 cgataaagaa attcaaacca aagaggaagc tcgcaccgag aactaggaag aggctgatat
     1561 agacacgatt ttgttggtac cagtctttag aaattgcttg ggtcaagctg tctttgcttt
     1621 tgaaactctc agtctgaatg gctcggtaag agatgcgggt cagttccttg ctttccttgc
     1681 tgatgactag ctcatttgta tcgaaatgca gttgcaagtc cttaggtaat tccttgattt
     1741 gacttggacc aatcacaaca gaaggggctt gactagctgt tccagtataa gttaatgtgc
     1801 catcgacaat tgtagcatgt tcagagagat cctggacaac ctcatttgtc agaggttcat
     1861 agacattatc gataaaagtt tctagcggat aggtctcctg ggagctgttt tggatagcaa
     1921 tgggtaccat agacaagctg ataaggaaga tactggtaaa gagaagttga aaccagttga
     1981 gctcgaaacg tttggacagg ggcttacgaa acccccaaat acttgaaaaa taggaaaatg
     2041 gatatggaag cataggtatc tttctaaaag gtgttttcta tatgagtatt attatataga
     2101 gaaatgcgct ttatttcaag tctaggagaa aaattgcttg ctacaaggat attatttaca
     2161 gtgacaattg ctaataatca atgaaaatca aagtgcaaac tagccacagg ttgctcaaag
     2221 cacaactttg aggttggaga taaagctgac gtggtttgaa gagattttcg aagagtataa
     2281 aatgaaaaag ggtggcgggg ataaattatc ccttgtcgcc accacttgta agtcctgaaa
     2341 caaagttctt ttgtaggaag aagaagagaa tacagattgg aagggcgatg aggatagcac
     2401 ctgctgagaa gtaggcaatc ttcaagtttt tcgcattgtt aacgaaggtt tggagaccta
     2461 cggcaacagt aaagtattct ttctcacgaa gcaagaaact agagaggatg tagtccccga
     2521 aaggtcccat gaaggcccag agagcttgta cggcaaccat tgggcgaaca agtggtagaa
     2581 caatttgcca gaagcggcgg aagtgtcctg caccgtctag ttttgcagat tcgtctaaag
     2641 acattggaac tgtatcgaag tagcctttca tgagccaagc attcatcggg ataccaccac
     2701 caacgtagag gaagatgagg aaccagttgt ggttaagggc gttcaacata agcgccataa
     2761 cgaagaaggc tgtcaaagcg gccatagttg gcaccatttg gatgatcaag aagaagacca
     2821 aactttgttt acgagccaag aagttgtaac ggctgtaagc ataaccagca agtacgatga
     2881 tacttgtttg aacagccatg gtaattaagg cgataatcaa agtgttgagg taccaagtac
     2941 cgtacaaggt ttcagtgaag aggcctttaa agttatcaaa attgaggtcg atattagtat
     3001 ctagtttaaa ggctgagacg ttacctgctt taaaggctga cataatggta atcaacagtg
     3061 gatagataat tacaattgat agaccaatca ggtaaaggta agtaaggctt tgagtcagtc
     3121 tacgtttgag tttaattgag ttattcatct tagacgtcct ccatatcaaa tgcgtgtagt
     3181 ttcttgaatg cgatcataga gattgagatg acaatgatag agataatcaa ggtaacagct
     3241 gccgccattg agtattgagg agatgtacct gttgtcaaac ggtagatcca tgagatcaag
     3301 atatcggttg aaccagctcc acctccgaca ctaccaggtc ctccaccatt gaagaggtac
     3361 atgatagaga agttgttaaa gttgaaggtg tattggctaa tcaaagtagg tgccgcaaca
     3421 gccaaaatca ttgggaaagt gatgttgcgg aatttttgcc aagcgttggc accgtcaata
     3481 taagctgctt cgtaaaggtc gttaggaata gattgcaaga tacccaaagt caaaacgtag
     3541 atgtatggga atccgagcca accttgcatc ataatcaagg caatcttagt ccaagttggg
     3601 tctgttttcc aaggaataag agctccatca aggaaaggaa ggaatttagc caagattggc
     3661 aatacttgag tgttgatagc accgacacta tcgttaaaca tgtttgagaa tgtcaagata
     3721 gtgatgaagg ctgggacagc ccaaggaaga aggaaaataa caccaaagat acgttttcct
     3781 ttgataaatg gttggttggc aatgatagct gtgaagatac caattacgat ttgtaaagta
     3841 gaagctgcca aagcccaaat gatagtccaa gaaagaacag aaccaaaggc agaacggaag
     3901 gtactcaagc tccaaatgtt tgtaaagttg gtcaaaccaa cccagtccaa caacttgttt
     3961 ggtggcaagt gttggaagtc gtagttggta aaggcgatca tcaaggttac gataactggg
     4021 aagataatcg cgaaggtcat ggcaacataa gatggaatga tcaagaggta agggaagcca
     4081 ttttcataaa tccctttgat catgtctttg agtgtgcgtg gaactggaat tccattgtta
     4141 atgcgttttg caatcgtatg tgcatctttg atatttgaga aataaaagag tacataaacg
     4201 attacaaaga ttagatggaa ggcaccacga atcagcataa agagggaatt atcacgacct
     4261 ggtttgtcac caagagtgat gaggttgctc aattcagggg ttgcaagtgc taggaagtaa
     4321 aggacaaata cgatggttac accaaggaag ataaaacctt tggctttttg tttattgtaa
     4381 atctgtccta acccaggaat gatagacagc agggctgctt tactaggttg ttgcttttcc
     4441 atattaactc ctttcatagg atactacttt tttataagaa agctaaatta tttgtgtctc
     4501 tattgataaa ttcaaagggg gatttgattt ccacccccct tgaacaaatt ttttattcac
     4561 caaatttttg tttgattgtt tctttgatca atgttacagc atcgttagca gctgttttag
     4621 catctttttg accacttaca gcatcaaaga gcatattttt cgctggatcc caaactgcag
     4681 acatttgaga gatgtttggc agtggttgag tgttcttgaa ctgtttgata acagctgttg
     4741 tcaactcatc gtttttacct tcagcgtatg aacgagcctc agtattagct gggatttcgt
     4801 tagtcttatc atataatact ttttgttgtt cagttgcaac aaggaagtct acaaattttt
     4861 gagaagcttc aaggttctta acggcttgag gaatgaccca agctttacca ccaccgaatg
     4921 cagcatattc ttttccattt ggaagagttg ggatagttgc aactccgtag tttactttag
     4981 catctttaaa ggcttgagct ttccaaggtc cgtcgatgat agcagctgtt ttaccttctt
     5041 ggaattgagt ttggattaag tttccagcac cttctgtatc ttgcatacct ttaggccatt
     5101 tttcgtacca agatttagcg tagttgatac ctacgataga accgtcgttt gcaagaccga
     5161 tgtctttagc gtctttaccg ttttggccaa agacgtaagc accgttaccg gcaagaagtc
     5221 catatgtata gtagaagttt gtccagtcag ctaggaaggc agtagtttta ccatcttcac
     5281 cagcgaatgc gtatttgcta tctttagcaa ggttttccaa gtcagcaaat gtttttggag
     5341 catctttcac caagtctttg ttgtagtaca taacaagtga ctcgataacg gcaggagcac
     5401 cgtaaacttt accattagca gctgttacaa gagatttagt tgtgtcgtct gttttagcac
     5461 catcgctcaa tttcacttct gaaagttgtc cgtcagaacc aaggctacct acacggtcgt
     5521 atggagccat cataacatca gggacattac cagattggtt gtcaagagaa agtttatcaa
     5581 gacctcctag agcatcacca gttttaagag tgacttttac tccagcttct ttttcataag
     5641 ctttagcaac ctcttcaata tagctcttat atccctcgtc tacatataca gtgagttctt
     5701 tgacttcaga tgaaccagaa tcagcaggct tatcagcagt tttgcttccg caagctacca
     5761 aaagcaagct agcaagtgta acagttccaa gcaccgcagt gctcttcata aatttagatg
     5821 acatagtgta ttcctcccaa agaatagcaa gttttattga taaggaaacg caaacgtttt
     5881 cctttatgag cttagtatag cacaaataga aaacggttgc aagtattttt tgtaaaaatt
     5941 ttaaaaaatt tttaagcttg atttgatagc ataattttgc attttaatag aagaaaagta
     6001 tgaaatagat aagaatacag tatttttaat aaaaatatat ggaatctgtc taaagaggga
     6061 aaccaggagg ggctacctcc ctgtttctaa tccctatcta ttttctatag acgtttgtgc
     6121 tttgttgcat ataaattcaa gctccctaag gaggttttgt actttgtaga ctgtctcgtg
     6181 agagtcaaac tttaggatta gatagtttta agttatcttt gctaaaatga gttagtctcc
     6241 ttaaaaataa tcaaaaaagt tttttaaaaa cgcttgcaat tatgcttgaa aaggagtata
     6301 cttataagta acgcaaacgt ttgcgtctgc aaaatacgca acgttccatt attttaacac
     6361 acgaggtgct attatgaaaa aacgtcaaag tggtgtgttg atgcacatct cttctcttcc
     6421 aggagcttac ggaatcggat catttggtca aagtgcttac gacttcgttg atttcttggt
     6481 ccgtacaaaa caacgttact ggcaaatcct tccattagga gcaactagtt acggggattc
     6541 tccttaccaa tctttctcag ccttcgcagg aaacactcat tttatcgatt tagatatctt
     6601 ggtggggcaa ggtttgttgg aagcaagtga ccttgaagga gttgactttg gtagcgatgc
     6661 gtctgaagtt gactatgcta aaatctacta tgcacgtcgt cctcttttag aaaaagcggt
     6721 gaaacgtttc tttgaagtcg gagatgttaa agattttgag aaatttgctc aagataacca
     6781 atcatggctt gagctctttg ctgagtatat ggctatcaaa gagtattttg acaatcttgc
     6841 ttggactgaa tggccagatg cagatgctcg tgctcgtaaa gcttcagcac ttgaaagcta
     6901 tcgtgagcaa ttggcagaca agttggttta ccaccgtgtg actcaatact tcttcttcca
     6961 acaatggttg aaattgaaag cttacgctaa cgacaaccac attgaaatcg ttggggacat
     7021 gccaatctac gtagcggaag attcaagtga tatgtgggca aatccacatc tcttcaaaac
     7081 agatgtcaat ggtaaggcta cttgtatcgc aggatgccca ccagatgagt tttctgtaac
     7141 tggtcagctt tggggtaacc caatctatga ctgggaagca atggacaaag acggctacaa
     7201 atggtggatt gaacgcttgc gtgaaagctt caaaatctac gatatcgttc gtatcgacca
     7261 cttccgtggc ttcgaatctt attgggaaat ccctgctggt tccgatacag cagcacctgg
     7321 tgagtgggtg aaaggtccag gctacaagct ttttgcagcc gttaaggaag aacttggtga
     7381 gctaaacatc atcgcagaag accttggctt catgacagat gaagtgatcg aattgcgtga
     7441 acgtactggc ttcccaggaa tgaagattct tcaatttgcc ttcaacccag aagacgaaag
     7501 cattgatagc ccacacttgg cacctgctaa ctcagttatg tacacaggaa cacacgataa
     7561 caatacggtt cttggttggt accgtaacga gattgatgat gcgactcgtg agtacatggc
     7621 tcgttacacg aaccgtaaag aatacgaaac agtggtacac gctatgcttc gtacagtatt
     7681 ttcatcagtt agctttatgg caattgcaac tatgcaagat ttactagaat tggatgaggc
     7741 agctcgtatg aacttcccat ctacccttgg tggaaactgg tcttggcgta tgactgaaga
     7801 tcaattgaca ccagctgtcg aggaaggttt gcttgacttg acaacaattt atcgccgaat
     7861 taatgaaaat ttggtagatt taaagaaata agacaataat caggagacaa ctaaacatgt
     7921 tatcactaca agaatttgta caaaatcgtt acaataaaac cattgcagaa tgtagcaatg
     7981 aagagcttta ccttgctctt cttaactaca gcaagcttgc aagcagccaa aaaccagtca
     8041 acactggtaa gaaaaaagtt tactacatct cagctgagtt cttgattggt aaactcttgt
     8101 caaacaactt gattaacctt ggtctttacg acgatgttaa aaaagaactt gcagctgcag
     8161 gtaaagactt gatcgaagtt gaagaagttg aattggaacc atctcttggt aatggtggtt
     8221 tgggacgttt ggctgcctgc tttatcgact caattgctac tcttggtttg aatggtgacg
     8281 gtgttggtct taactaccac tttggtcttt tccaacaagt tcttaaaaac aaccaacaag
     8341 aaacaattcc aaatgcatgg ttgacagagc aaaactggtt ggttcgctca agccgtagct
     8401 accaagtacc atttgcagat tttactttga catcaactct ttacgatatt gatgttactg
     8461 gttatgaaac agcgactaaa aaccgcttgc gtttgtttga cttggattca gttgattctt
     8521 ctattattaa agatggtatc aactttgaca agacagatat cgctcgcaac ttgactctct
     8581 tcctttaccc agatgatagt gaccgtcaag gtgaattgct ccgtatcttc caacaatact
     8641 tcatggtttc aaacggtgcg caattgatca tcgacgaagc aatcgaaaaa ggaagcaact
     8701 tgcatgacct tgctgactac gcagttgtcc aaatcaacga tactcaccca tcaatggtga
     8761 ttcctgaatt gattcgtctt ttgactgcac gtggtatcga gcttgacgaa gcaatctcaa
     8821 ttgttcgtag catgactgcc tacactaacc acacaatcct tgctgaagcg cttgaaaaat
     8881 ggcctcttga attcttgcaa gaagtggttc ctcacttggt accaatcatc gaagaattgg
     8941 accgtcgtgt gaaggcagag tacaaagatc cagctgttca aatcatcgat gagagcggac
     9001 gtgttcacat ggctcacatg gatatccact acggatacag tgttaacggg gttgcagcac
     9061 tccatactga aatcttgaaa aattctgagt tgaaagcctt ctacgacctt tacccagaaa
     9121 agttcaacaa caaaacaaac ggtatcactt tccgtcgttg gcttatgcat gctaacccaa
     9181 gattgtctca ctacttggat gagattcttg gagatggttg gcaccatgaa gcagatgagc
     9241 ttgaaaaact tttgtcttat gaagacaaag cagctgtcaa agaaaaattg gaaagcatca
     9301 aggctcacaa caaacgtaaa ttggctcgtc acttgaaaga acaccaaggt gtggaaatca
     9361 atccaaattc tatctttgat atccaaatca aacgtcttca cgagtacaaa cgccaacaaa
     9421 tgaacgcttt gtacgtaatc cacaaatacc ttgacatcaa agctggtaac atccctgctc
     9481 gcccaattac aatcttcttt ggtggtaaag cagctccagc ctacacaatc gctcaagata
     9541 tcattcactt gatcctttgc atgtcagaag ttattgctaa cgatccagca gtagctccac
     9601 acttgcaagt agttatggtt gaaaactaca acgttactgc agcaagcttc cttatcccag
     9661 catgtgatat ctcagaacaa atctcacttg cttctaaaga agcttcaggt actggtaaca
     9721 tgaaattcat gttgaacgga gctttgactc ttggtactat ggacggagct aacgtggaaa
     9781 tcgctgagtt ggttggtgac gaaaacatct acatctttgg tgaagattca gaaactgtta
     9841 tcgaccttta cgcaaaagca gcatataaat caagcgaatt ctacgctcgt gaagctatca
     9901 aaccattggt tgacttcatc gttagtgatg cagttcttgc agctggaaac aaagagcgct
     9961 tggaacgtct ttacaatgaa ttgatcaaca aagactggtt catgactctt cttgatttgg
    10021 aagactacat caaagtcaaa gagcaaatgc ttgctgacta cgaagaccgt gacgcatggt
    10081 tggataaagt catcgttaac atttctaaag caggattctt ctcatctgac cgtacaatcg
    10141 ctcagtataa tgaagacatc tggcacttga actaatactc ttcgaaaatc tcttcaaacc
    10201 acgtcagctt tatctgcaac ctcaaagcgg tgctttgagc aacctgcggc tagcttccta
    10261 gtttgctctt tgattttcat tgagtataag atacaaattt atactaatac attttgtaaa
    10321 aaagtgagtt tcgattgaaa ttcgcttttt taaatgctgt ggatttgggt caatcttgtc
    10381 taaaaatagg gaaatcctag atacagtgaa ggctttaaat gctggttttt actgtcttca
    10441 gccttatatt ttttcgtagt tggttacctc atatctcttg tattcgctta cataaagtat
    10501 tataatataa ttgtaggaaa gaaggtgttt ttatgatata cacacttaaa ttggtgttgt
    10561 ttattacctt tcttgtaata agcttgttac ctgataagat ttttggaaaa aataaaaaaa
    10621 tttggaaaat agtttttgca atattgacgg cagtggcagc attgtcattt atgtactaag
    10681 ttattttaag aatgtaggga aataaaccct acattctttt tagttttttc tgttttctaa
    10741 attctattta tccaagcgat tcaacatttc ttgcttcttc gcttcaagtt ctgcacgctt
    10801 ttcttcgatt tcggcatgtt ttttctcgag ttcagaacaa cttgcaccat tgctaaattc
    10861 ttttcgccat caggagatag ggtgagtcga catgtctatt actcacccaa agcagtccta
    10921 caaagcagga attttctgtt acttttttgg aaatagtaac gtttatacag ctttgacact
    10981 tcgtatcaaa gcgccaaaca cactccgagg gatttacaga aagcagaaaa ggaatgatct
    11041 ggtataagat cattcctttt ctctcttttt ctttaagtaa ttatatacaa tgtacgacga
    11101 agtcgtcatt gcaatgctga tccaccacct aaagggaact ttaaacaaca ttgataagat
    11161 aaagaatata aacaacgaaa atacgttata cccaattaat tttattgtat atctcatgat
    11221 taaaagttaa tccttccgtt gttaggaatg gcatcatttt tatcccataa ttgtgctaaa
    11281 taagtccccg gtgataataa attcatagcg aattctaaag caacatcatt tacaaaccaa
    11341 ctacctagat atctagaaat tgctgaacga atagcacttt ttgctgcatg ttttcctttt
    11401 actttaatta gatttgcaag gcctgcagta gttcctccta atgctaaagc tattgcagta
    11461 tctaatagag cacccatttg attaactgta ataccttgcc aagctgctct aaatggagag
    11521 tatgtaggtg ggattgtata atcgccttgt aattgtcggt taattacttc tttgatccat
    11581 tgttgtgaga cgtctggatg aaaagattgg atttcgtttg caagtgtatt gatttgttct
    11641 tctgttagag aagtgacagg ttgaagttcc atatttgttt caatttgtga tacttgttca
    11701 gaagcgtata cagctgaaac acttggaatc gctgatacaa ttaacacaat tgacgtcaaa
    11761 aaaaccgaaa taaatttcat taatttgttc atgagctttt ctccttttta tttgtatctg
    11821 cttacatttt atcatatact gttattatag tcaaaaaaat atgctattat gttaaaaaaa
    11881 tatttttcaa aatataaatg gacggattta ttttggattt tatttgttat tttgacctgc
    11941 ctctatattg gtaaccatga tttgtttact atcaatcatc aagaattctc ttttcgtggt
    12001 agcgtttggg gtctggtact ggccttatat cacttattgt tcattgataa gtttgtaatt
    12061 tcgaatcgaa aataaagatt agaactatga ttgactggct acttttaata ttgattttgg
    12121 aggaagattt tgtctctatt atttattatt ttaaatttat ttattttgta taagatctat
    12181 tctttgaggc gggaaaaatc gaaatacttg atttatacgg tctatatcat atttggggta
    12241 aatgtagtat atggtattca atggttatta aaagaactga tttcaactat ttccccttaa
    12301 tgtgtatgaa aactataaca aaacgcataa gattaaggtt tttaagcacc tgttcttatg
    12361 cgtttttgta atattgaaga ttttcggtaa gttttatacc tttgggaagt ctagtttaga
    12421 atgctttccc aaccagaatc tctgcttcga tggtaatctc tgtcagttgg ctccagtcaa
    12481 tcttgctctg gtcaacgtga aagaggagag gagtcatact gagtagggct tggagttgtt
    12541 ctgctgtgat agtcttagtc agagaggcag tttgactaga taggatggta aagtgttctt
    12601 ggaaatgctc cttgatatct tggttagaat actccttgtt tgtcagctgg tcctgtactc
    12661 tttgacggat ttctttgagg tgattttcag ttgggataac ctttatcaag ataccgtctt
    12721 tggataaaac gcgacgaaat tctccatagt tggcaggtga gaagatatca agcagaatat
    12781 ccatgttagc gtcttttata ggaaggcgtg ccaagtcgcc aacgaaccaa ttgactgccc
    12841 agttgggttc acttttagca gcgatttgga ctgaatcttt ggagatgtca aaggcataga
    12901 aagttttttc agagtgactt tcttgtagtt tgcgagaata gaatccttca ccacaaccga
    12961 tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa gtcagataca gcatctaaga
    13021 tagcttggta aaagccggct tctaggattt gttgacggtt ttgaaaattt tccttgtcat
    13081 agttagcgga ttgcttgatt tgaggtgcta gattgacata gccaaatttc gccaagtcaa
    13141 aagaatgacg gttgcagcac ttgaaattag tctctaacag agtcagattt tcttgacaga
    13201 tagggcaggc aaaggcagtc gcagaagcaa aacgctgaag tttgggcttg agatttgtat
    13261 tcatagttta agtgtatcaa aagaggaaaa tgaaagcaac tttaggaata agtagatggg
    13321 agattcagta gaaataaaac taatactctt cgaaaatcaa attcaaacca cgtcaacgtc
    13381 gccttgccgt actcaagtac agcctgcggc tagtttccta gtttgctctt
//
LOCUS       DAVMBH010000050        13271 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVMBH010000050 DAVMBH010000000
VERSION     DAVMBH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.050"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            176..1015
                     /locus_tag="VYP30_001727"
     CDS             176..1015
                     /locus_tag="VYP30_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808681.1"
                     /translation="MSYFLLNGILLSTFLGWLFNISLVTVAVEGIGFAYGFNGGLTHK
                     NFYAITILVSYILLFISRKHGTKYQVDSLVLWFDLFLLLVSNTRTIYIILVVFWIVVH
                     SGFIKYIKKNHRPVIITTWLVISLLSIIFFFKHIINNSESYTHRVLGIVNFFKYYESS
                     KFHLFFGDAELAFGDMTKGYTHNIRSVLGWDGTVEMPLLSVMIKNGYVGLIGYGVVLF
                     KFISSVLSMEDRRVKNIGLSILIPLLLSAMVENYIVNISFVFMPVCFCILCSIKNIEF
                     KNN"
     gene            1025..1993
                     /locus_tag="VYP30_001728"
     CDS             1025..1993
                     /locus_tag="VYP30_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1808682.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            2000..3238
                     /locus_tag="VYP30_001729"
     CDS             2000..3238
                     /locus_tag="VYP30_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV1808683.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLAHNLLFINNKINVFILNKTYRVNLHQFLINKISEASVSFVDIYRSPLPILYGYG
                     PFLMDITKPLVNFFEDSGFTYDSGTILDKTDYFKFYLKWLWSYKFFLFRLNHIKEGNS
                     EFEKSFKIIRRYYKMGRQYE"
     gene            3231..4619
                     /locus_tag="VYP30_001730"
     CDS             3231..4619
                     /locus_tag="VYP30_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEV1808684.1"
                     /translation="MSKYKELAKNTGTFALANFSSKILIFLLVPIYTKVLTTTEYGFY
                     DLVYTTIQLLVPILTLNISEAVMRFLMKEDVSKKSVFSIAILDIFLGSIIFCLLLLVN
                     QIFSLSELISQYSIYIMAIFAFYTLNNFLIQYSKGIDKIGVTAISGVISAAVMLSMNI
                     LLLVVLNWGLLGFFIANICGYVIPCVYIIVKLKLWDLFELKIDRSLQWEMIYYTLPLI
                     LNTLSWWVNNTSDRYIITVIIGIQASAIISVAYKIPQIFSTISAIFIQSWQISAIKIQ
                     EEKEGNTFISKMLLYYNALLLIIASGIILFVKPISNILFGASFYSAWTLVPFLIISSL
                     FNAISGYIGAIMGAKMDTKNIAKSALVGMIANVFLNIVLTFLMGLQGITISTMIASFL
                     IFYMRKDSVEEIAPETYRAIYLSWFLLVVEASLLVYIDFIIGATLVTLINLFLLKDTL
                     KPLCLKLLKGFK"
     gene            4622..5770
                     /locus_tag="VYP30_001731"
     CDS             4622..5770
                     /locus_tag="VYP30_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV1808685.1"
                     /translation="MNILQYIKILARTIFMLLISTVLLPVRLKNNKILFINFNGKGYG
                     DNPKSICEYLRTTYPDLDLVWLARDNEGFPDGVRVVKYGTFQAFYEQASSKVWVYNVR
                     AFARILKKRGQIYIQTWHGASSFKLIEKQADLPINYVLEAKYDARVTDIMISDSRKQT
                     EEFQKYFWYSGEIFEVGMPRNDALFHYKEDYDKLNNIRKELSIHSDDYVILYAPTFRD
                     DGDASYLDINFERLLQCVEHGIKKKCKFLIRLHPNHSHLCNNISFNKNIINATFYSDM
                     QELTLLADVLVTDYSSSIFDFMLLNKPYVRYVNDLEKYAELRGVSDTYYELPDSIIKT
                     AEELYDLLPKKIENFDYDSIKKYRNEILCPIFNGTASENVGRRIIQEL"
     gene            5806..6834
                     /locus_tag="VYP30_001732"
     CDS             5806..6834
                     /locus_tag="VYP30_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1808686.1"
                     /translation="MKNNDLKIGSGAIHQISATLSQNSISGKILYCADPVVDDLYGSI
                     VRSQIEEIGRVKEESCNYNTIAYAMNIAERAIATDIDCIVGMGGGRVLDVCKYASFIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVERGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLV
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSTRNLHGIQVALGTVAVLKLIENS
                     VDTVVDYLQRFEVHINPKLLGIDEELFIYCMQHATKMRSNRYTYLHEVDLSTDRLKQI
                     YKELISEL"
     gene            6850..7554
                     /locus_tag="VYP30_001733"
     CDS             6850..7554
                     /locus_tag="VYP30_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV1808687.1"
                     /translation="MKALILAAGLGTRLAPITNEVPKSLVPVNGKPILMKQIENLYQN
                     NITDITIIAGYKSSVLTDAVTEKYPEINIIDNVDFKTTNNMYSAYLGKAAMGDSDFLM
                     MNADVFYDASVIKSLLLHKAPNAIVTDLGIYIEESMKVVEKNGRLVEISKQISPEETL
                     GASIDVYKFSYEAGARFFEKCKEFIEDKRELQMWSEVALNAILSEVEFVACPLEGRWL
                     EIDNHEDLVAAEKLFA"
     gene            7569..8402
                     /locus_tag="VYP30_001734"
     CDS             7569..8402
                     /locus_tag="VYP30_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV1808688.1"
                     /translation="MKLTNRVDYFGADISELQNKKLFLFDMDGTIYEEDRLFEGTLEL
                     LDYIHNIGGEYIFITNNSSKSVVDYVEKVNRLGIKAERDNFFTSAQATIVYIKENYPK
                     SKVYCQGTKSLIKELSDAGIDVTEQVSADIDVVLVGFDTELTSDKIRNTCEILSTKDV
                     PFIATNPDIRCPVSFGFIPDCGSICDMISKSVDRKPVYIGKPEPTMVDIVRKKLNYSL
                     FETVVIGDRLYTDIMTGINAGVTSVCVLTGEATVNDIQQDSIKPTYTFKNVKEMWKGI
                     V"
     gene            8562..9431
                     /gene="rfbA"
                     /locus_tag="VYP30_001735"
     CDS             8562..9431
                     /gene="rfbA"
                     /locus_tag="VYP30_001735"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1808689.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSTMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            9432..10040
                     /locus_tag="VYP30_001736"
     CDS             9432..10040
                     /locus_tag="VYP30_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1808690.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKKICKKERI"
     gene            10037..11086
                     /gene="rfbB"
                     /locus_tag="VYP30_001737"
     CDS             10037..11086
                     /gene="rfbB"
                     /locus_tag="VYP30_001737"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1808691.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPGVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            11152..12003
                     /gene="rfbD"
                     /locus_tag="VYP30_001738"
     CDS             11152..12003
                     /gene="rfbD"
                     /locus_tag="VYP30_001738"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1808692.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITNEEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            12079..12513
                     /locus_tag="VYP30_001739"
     CDS             12079..12513
                     /locus_tag="VYP30_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808693.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHIIHQKINLKVPNYRQEEDWARMDL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            12589..13035
                     /locus_tag="VYP30_001740"
                     /pseudo
     CDS             12589..13035
                     /locus_tag="VYP30_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13106..13264
                     /locus_tag="VYP30_001741"
     CDS             13106..13264
                     /locus_tag="VYP30_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1808694.1"
                     /translation="MSLLETAKRHQLNSEKYLFYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
BASE COUNT         4379 a         1916 c         2642 g         4334 t
ORIGIN      
        1 aatcgctaat agaattgctt atttttctat tatttcattt ttgtttatca tagggattaa
       61 tttacaaaat cttcctttct caacaaagat ttatttatcg ttttccatgc ttattatttc
      121 tagtctatcg actttaccga ttaaattaat aaataatata aatgatttta gaagaatatc
      181 ctatttttta ttaaatggca tcctattatc aacattttta ggttggctat ttaatatttc
      241 attagtaact gttgctgttg aggggattgg ttttgcatat ggatttaatg gtgggttgac
      301 gcataagaat ttttatgcaa ttacaatttt agtttcctat atcctattgt ttattagtag
      361 aaaacatggt acgaagtacc aagttgatag cttagtatta tggtttgatc tttttttact
      421 tttagtatct aacacacgga caatatatat aatattagtt gttttttgga tcgttgttca
      481 tagcggattt attaaatata taaagaaaaa tcacagacca gtaattataa cgacatggtt
      541 agtaatttct ttattatcta taatattttt tttcaaacac attataaata atagtgaatc
      601 ctatactcat cgtgttttgg gtattgttaa tttttttaaa tactacgaat ctagcaaatt
      661 tcatttattt tttggtgatg ctgagttagc ctttggtgat atgacgaaag gttatactca
      721 caatataaga agtgttttag gttgggatgg aactgtggaa atgccgttgc taagtgttat
      781 gataaaaaat ggttatgtcg gcttaatagg gtatggagta gtcttattta aatttatatc
      841 ctctgtatta tctatggaag atagaagagt aaaaaatatt ggcttatcca ttctaatacc
      901 tctacttcta tcagcaatgg ttgaaaatta tatcgttaat attagctttg tattcatgcc
      961 ggtctgtttt tgtattttat gctcaataaa aaatatagaa tttaaaaata attgaaagtg
     1021 atttatgaaa aaagtaagta ttattctacc tgtctacaat gttgaacagt atataaaaaa
     1081 atgcttagaa tcaattcaac aacaaactta tccaaatttg gaagtaatca ttgttaatga
     1141 cggagcaacc gataaaagcg ttgaatactg tgagcaaatt tgtaagatag attctaggtt
     1201 ttctgtcact cacaaagaaa atggtggact ttccgatgca agaaatgtcg gtatagataa
     1261 agccaaggga gattacctca tttttgttga cagtgatgat tttgtctctc aagatatggt
     1321 atcttattta gtatctagta tggagaacaa tgaggcagac attgctattt gcgatcctgc
     1381 tcattattat agtgaccgtc aaaacaatga tcttaatatt ttttatccag catcaagcgt
     1441 taaggtttac gaaaaaacgg aagctctatg tgagatgttt tatcaaaaat cttttttggt
     1501 atctgcttgg gctaagatat ataaaaagga actatttgat gatatcagat tccctgttgg
     1561 gaagttattt gaagatagtg ctgttatgta tctgcttttt gaaaaatgtg aaaagatagt
     1621 atattctaat gcgaaattat atgcctatgt gcatagagac aatagtatta caacaaagaa
     1681 gttttcagat aaagatttag atattttaga catttcaaat actattcttg atcactatag
     1741 tgggaacttt agagtttata aagcggcagt ttcctataaa gtttcggcat gttttagaat
     1801 tttgttgaac tcatcttcag aaaaaaaata taatcaaata caaaaagatt gtatgacata
     1861 tattttacga aattggagaa atgtgttatt tgataaaaat gtccgattaa agaacaagct
     1921 tgccttgatt tctataactc ttttcaatcc ttttgttaaa tttatctata gcaaagtaaa
     1981 cagatgggaa taatagcaaa tgaacaaata tgaagaaaga tatcaggaag atttatctaa
     2041 gaatgatttt gagaaactaa tcaatagaag atacctatcg gataaagaac tacaagttga
     2101 atatgtaaaa aaaggaacag tgttacctcc caaggtcttt gaaatgaaac tatcaaataa
     2161 acttggtcta caaaaagctt tgcatgggaa aggtggtgtt gtagattcaa aggggaatta
     2221 tgttgaactt tctgaacaaa aagcagttgg gatgagaaat cgagtctatg gatcttacaa
     2281 atttaaccat aaaaatttgg ctatcagaaa tgaaaaagtt atttacctaa actatttcat
     2341 aaatcagtgg ggacattttt tactagatgt tgtggggaga ttatggtatc cattactaaa
     2401 agatactgat actaaactgg attacacatg ttatgctggt acagaaacga aacttgaagg
     2461 aaactattta gagtttttag aactcctcgg tatagataaa tcacgcttaa ttttgataaa
     2521 tcgcccaact caattctcag agataattat acctgaaagt tcaattctgc caggtgaata
     2581 ttatacaaaa gaatataaaa tgctttttaa ttctttagta gcaaatgtta aattagataa
     2641 caatttagaa tcaaaaaaaa tttattgttc acgagctagg ctagatttag caaaaggtaa
     2701 agagttcggt gagaatggta ttgaaaaggt cttcttaaaa aacggttata ctccagttta
     2761 tatggaaaca atgtctttga aagaacaaat aagaacgcta ttatcagcta caacaatagt
     2821 attaactagc ggttcgttgg ctcataattt attgtttata aacaataaaa ttaatgtttt
     2881 tattttaaat aaaacttata gagtaaatct tcaccaattt ttaataaata aaatctcaga
     2941 agctagtgtg agctttgtgg atatttatcg ttccccgtta cctattttat atggatatgg
     3001 tccattttta atggatatta ctaaaccttt agtgaatttt tttgaggaca gtggcttcac
     3061 ctatgattca ggaaccattt tagataaaac tgattatttt aaattttatt taaaatggtt
     3121 atggagttat aaattctttc tatttagact gaatcacatt aaagaaggaa acagtgaatt
     3181 tgagaagagt tttaaaataa ttagaagata ttataaaatg ggacgacagt atgagtaaat
     3241 ataaggaatt agcaaaaaat acaggtactt ttgctttagc taatttttca tcaaaaatat
     3301 taattttttt gttagtacct atatatacaa aagttctaac aacgacagag tatggttttt
     3361 atgatttggt ttatacaaca attcagctcc ttgtaccaat cctgacattg aatatatctg
     3421 aagcagttat gagattttta atgaaagaag atgtttcaaa aaaatcagtt ttttcgattg
     3481 caatacttga tatattttta gggtctatta ttttttgttt gttactactg gtcaatcaaa
     3541 tattttcttt atcggagtta atttctcaat atagcatata tatcatggcg atttttgctt
     3601 tttatacact taataatttt ttgatacaat actctaaagg gattgataaa ataggtgtaa
     3661 cggctatctc tggagtcata agtgcagcag ttatgctttc gatgaatatt ttattgttag
     3721 tggtattaaa ttggggacta ctaggttttt ttatcgcaaa tatttgtggg tatgtcattc
     3781 cttgtgtata tataatagta aaactaaaat tatgggattt atttgaactt aaaattgata
     3841 gatcgttaca gtgggaaatg atatattata ctttaccttt gattttaaat actttaagtt
     3901 ggtgggttaa taacacttca gataggtata ttataacagt aattataggt atacaagcta
     3961 gtgcgattat ttcagttgct tataagattc cacaaatttt ttccacaatt agcgctatat
     4021 tcattcaatc gtggcaaata tctgcaataa aaattcagga agaaaaagaa ggtaacacct
     4081 ttatatcaaa aatgctttta tattataatg cactcttgct gattatagcg agcggtatca
     4141 ttctatttgt aaaaccaatc tctaatatac tcttcggagc ttcattttat tcagcgtgga
     4201 cgcttgtacc gtttttaatt attagcagtt tgtttaatgc gatttcgggt tatataggag
     4261 cgataatggg cgctaaaatg gatactaaaa atattgctaa atctgctttg gttggaatga
     4321 tagctaatgt ttttttaaat attgtattaa catttttaat gggactacag gggattacaa
     4381 tctcaactat gatagctagt tttcttattt tttatatgag aaaagatagt gttgaagaaa
     4441 ttgctccaga aacatataga gctatttatc tttcgtggtt tttgttagtg gttgaggcta
     4501 gtcttttggt ttatatagat tttattattg gggctacatt agttacatta atcaatttat
     4561 ttttattaaa ggatactctt aaaccattat gtttaaaatt attaaaagga tttaaatgaa
     4621 aatgaatatt ctacaataca ttaaaatttt ggctagaact atttttatgc tattgataag
     4681 tacagtgtta ttacctgtca ggttaaaaaa taataagatt ctatttatta atttcaatgg
     4741 gaagggttat ggtgataatc ctaaaagtat ttgtgagtat cttagaacta cttacccaga
     4801 tttagatttg gtttggcttg caagagataa cgaaggtttt ccagatgggg ttagggttgt
     4861 taaatatggg actttccaag ctttttatga gcaagcgagt tcgaaggttt gggtatataa
     4921 tgtaagagct tttgcaagaa tactaaaaaa acgaggacag atttatattc aaacttggca
     4981 tggtgcttct agttttaagt tgatagaaaa acaagctgat ttaccaataa attatgtttt
     5041 agaagctaag tatgatgcaa gagtcacaga tataatgatt tcagatagca gaaaacaaac
     5101 tgaagaattt caaaagtatt tttggtattc aggagaaatt tttgaggtgg ggatgccgag
     5161 aaatgatgcc ttgtttcact ataaggaaga ctacgacaag ttaaataata tcagaaaaga
     5221 actaagcatt cattcagatg attatgttat tttatatgcc cctactttca gagatgatgg
     5281 ggatgcatct tatttagata taaattttga acggcttttg caatgtgttg aacacggaat
     5341 taaaaagaaa tgtaaattct taattaggtt acaccctaat cactcccatt tgtgtaataa
     5401 tatttcattt aataagaata taatcaatgc tacgttttat tcagatatgc aagagcttac
     5461 tttgttggca gatgttttag tcacagatta ttcttcctcg atatttgatt ttatgctttt
     5521 aaacaagcct tatgtcagat atgtgaatga tttagaaaaa tatgctgagc ttaggggggt
     5581 atcagataca tattacgaat tgccggattc gattattaaa actgctgaag aattgtatga
     5641 cttactgcct aaaaaaatag aaaattttga ttatgattct ataaaaaaat atagaaatga
     5701 aatactgtgt ccaatcttta atggaaccgc tagtgaaaat gtaggaagga gaataattca
     5761 agagttgtga agtaaaacat tgggttattt ttaaggtaac gagatttgaa aaataatgat
     5821 ttaaagatag gaagtggagc tattcatcaa atttccgcta cactttctca aaatagtatt
     5881 tcgggaaaga ttttatattg tgctgatcca gttgtcgatg acttgtacgg ttcgatagta
     5941 cgttcacaaa tagaggaaat tggtcgggta aaggaagaaa gttgcaatta taatactatt
     6001 gcttatgcga tgaatatagc agaacgggct attgccacag atattgactg tattgtggga
     6061 atgggaggag gtcgtgtttt agatgtctgc aagtatgcat cttttatttc gaaacgtcct
     6121 tacctatcga ttccgacaac agcagcaaat gatggcattg cttccccagt tgctgttttg
     6181 aaaaggcagg atgatagacc aaaaagctta ggggcggcta tcccctcaat gacactaatt
     6241 gatattgatg ttattgcatc aggacctata caaaatataa aagctggtat cggtgataca
     6301 atatccaatt acactgcatt gaaagattgg gagttggcag ttgagcgagg gaaagatgag
     6361 atgcatggtt ttgcatatct aatgtcgcaa aattctttag atgctttaat gaaaacgaag
     6421 tataattcta ttacccctga ttttattgaa gttttggtaa actctttagt tttatcaggc
     6481 attgcaatgg attttgcggg aagtagtaga cctgtcagtg ggtcagagca cttatttagt
     6541 catgcattag attactatgg ttctacaagg aatcttcatg gaattcaggt tgcattaggt
     6601 acagtcgcag ttttgaaatt aattgaaaat tctgttgata ctgtagtgga ttacttgcaa
     6661 agatttgagg ttcatattaa cccgaaactt ttggggatag atgaagagtt gtttatttat
     6721 tgtatgcaac atgctacaaa aatgagaagt aatcgctata cctatctgca tgaagttgat
     6781 cttagcacag atagattgaa acaaatatat aaggaactca taagcgagtt gtagagaaga
     6841 gaggaaaaaa tgaaagcact tattttagca gcagggttag gaacacgtct agctccaatt
     6901 accaatgagg taccaaaatc tttggtacca gtcaatggta agccaatttt gatgaaacaa
     6961 attgaaaatt tatatcaaaa taatattaca gatattacga ttattgctgg atataagtca
     7021 tctgtattaa cagatgcagt tactgaaaag tatccagaaa ttaatattat tgataatgtt
     7081 gattttaaaa cgactaataa tatgtattca gcctatctag gaaaagctgc aatgggtgat
     7141 agtgacttct taatgatgaa tgcagatgta ttttatgatg cttctgttat taaaagtctg
     7201 ttgcttcata aagctccaaa tgcaattgta actgatttag gtatttatat tgaagagtct
     7261 atgaaagtcg tagaaaaaaa tggtcgttta gtagaaattt ctaaacagat ttcacctgag
     7321 gaaactttag gagcttctat tgatgtttat aaattctctt atgaagcagg tgctcgattc
     7381 tttgaaaagt gtaaggaatt tattgaagat aaacgagaac ttcaaatgtg gagtgaggtt
     7441 gctcttaatg caattctttc tgaagttgaa tttgtagcat gtccattaga gggtcgttgg
     7501 ttagaaattg ataatcatga agacttagtt gctgcagaaa aactatttgc ttgaaccgaa
     7561 tacggagaat gaaattgaca aatagagttg attattttgg tgctgatatt agtgaacttc
     7621 agaataaaaa attattctta tttgatatgg atggtaccat ttatgaagaa gataggttgt
     7681 ttgagggtac tctcgaatta ttagactata ttcataatat tggcggtgag tatattttta
     7741 ttacaaacaa ttcatctaag tctgttgttg actatgttga aaaagttaac agattaggta
     7801 ttaaagctga acgagataat ttttttacct ctgctcaagc cacaattgtt tatattaaag
     7861 aaaattatcc taaatctaaa gtttattgcc aaggaacaaa atctttgata aaagaactat
     7921 ctgacgcagg aattgatgta actgagcaag ttagtgctga tatagatgtt gttcttgttg
     7981 gttttgatac agaattaacc agtgataaaa ttcgcaatac ctgcgagatt ctatcaacaa
     8041 aggacgtacc tttcatagct actaaccctg atattcgctg cccagtatcg tttggattca
     8101 tcccggattg tggttctatt tgtgatatga ttagtaaatc agtcgatagg aaacctgttt
     8161 acataggtaa acctgaacct acgatggttg atattgttcg aaaaaaatta aattattctc
     8221 tatttgaaac agttgtgatt ggagatcgct tgtatacgga tatcatgact ggtataaatg
     8281 caggagtaac ttcagtttgt gtgctgacag gagaagcaac ggtgaatgat attcaacaag
     8341 atagtataaa accgacttat acatttaaaa acgtgaaaga aatgtggaaa ggaattgtct
     8401 gattttttca ttctgaatag tgaattcatg aatactgtca aaatactcgt atgtatttaa
     8461 attgatttta ttattttaat aatggacaaa ttaaaattat ttttctcccc aaatcgttcg
     8521 tgaacgtaaa gtactcatca acaaagaaag gtaccccttt tatgaaaggt attattctag
     8581 caggtggttc gggaactcgc ttgtatcctt tgactcgcgc tgcatcaaaa caacttatgc
     8641 cggtttatga taaaccgatg atttactacc cactttcaac attaatgttg gctgggatta
     8701 gggatatttt gattatctca actcctcaag atttgcctcg ttttaaagag cttcttcaag
     8761 atggttctga gtttggtatt aaactttctt atgctgagca accaagtcca gatggtttgg
     8821 cacaagcctt tatcattggg gaagagttta tcggtgacga tagcgttgcc ttgattttag
     8881 gtgacaatat ctaccatggt cctggtctga gcacaatgct tcaaaaagca gccaagaaag
     8941 agaaaggtgc gactgttttt ggctaccatg tcaaggatcc agaacgcttt ggtgttgtag
     9001 aatttgatga aaatatgaat gctatctcca tcgaagaaaa gccagaatac cctcgttcaa
     9061 actatgcagt gacaggactc tatttctatg ataatgatgt agtagagatt gccaaaagta
     9121 ttaaaccaag tcctcgtggt gaattggaaa ttacagatgt caacaaggct tacttggatc
     9181 gtggtgattt gtctgttgag ctcatgggac gtggttttgc ttggttggat actggcactc
     9241 atgaaagttt actagaggct tcgcagtaca tcgaaacagt ccaacggatg caaaatgttc
     9301 aggtagcaaa cttggaagaa attgcttacc gtatgggcta tatcagtcgc gaagatgtgt
     9361 tggccttagc ccaaccactt aagaaaaatg aatacggaca gtatctactc cgtttgattg
     9421 gagaagcata gatgacagat aattttttcg gtaagacgct tgcggcacgc aaggttgaag
     9481 ctattccagg catgttggag tttgatatcc ccgttcatgg agataatcgt ggctggttta
     9541 aagaaaattt ccaaaaggaa aaaatgcttc cacttggatt tccagagtct ttctttgcag
     9601 aaggaaaatt gcaaaacaat gtatccttct cacgtaaaaa tgtccttcga ggcctccacg
     9661 cagagccttg ggataagtac atctctgtag cagatggagg gaaagttctg ggttcttggg
     9721 ttgatctacg cgagggtgaa acctttggga atacctatca gacagtgatt gatgcgagta
     9781 agggaatctt tgttcctcga ggcgtagcta atggcttcca agttttatca gatacagtgt
     9841 catatagcta tctggtcaat gattactggg ctcttgaact caaacccaag tatgcctttg
     9901 tgaactacgc tgatccaagc cttggtattg aatgggaaaa tattgcagaa gcagaagttt
     9961 cagaagcaga taaaaatcat ccactactta aggatgtaaa acctttgaaa aagaagattt
    10021 gtaaaaagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg gagctggctt
    10081 tatcggttct aactttgtcc attatgttta cgagaacttt ccaggtgttc acgtgacagt
    10141 cctagataag ttgacttatg ctggaaatcg cgcgaatatt gaggaaattt taggtaatcg
    10201 tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt tggctgctca
    10261 agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc tcaatgatcc
    10321 atcgccattt attcatacta acttcatcgg aacctatact cttttagaag ctgctcgtaa
    10381 gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc tccctttacg
    10441 cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg aaacaaaata
    10501 caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg tcaaagcctg
    10561 ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact acggtcctta
    10621 tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg gaattaagcc
    10681 aaaactttac ggtgaaggta agaatgttcg tgactggatt cataccaatg accattcttc
    10741 aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga ttggggctga
    10801 tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg gacaagctac
    10861 ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg cgattgatgc
    10921 cagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg aagctgggct
    10981 caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag aaaaagaagc
    11041 tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag caggaaatag
    11101 ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga gatgatttta
    11161 attacagggg caaatggcca attaggaacg gaacttcgct atttattgga tgaacgtaat
    11221 gaagaatacg tggcagtaga tgtggctgag atggacatta ccaatgaaga aatggttgaa
    11281 aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta caccgctgtt
    11341 gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac ggggacaaaa
    11401 aatgtcgcaa aagcatctga aaagcatggt gcaactctag tttatatttc tacggactat
    11461 gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg accagatcca
    11521 cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa gcatgtgtct
    11581 aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa cttcgttttt
    11641 accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga ccagtacggt
    11701 cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga aaatcgtaag
    11761 gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg gtatgatttt
    11821 gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc cagtcaattt
    11881 ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc caaagctact
    11941 ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca agaagtgaga
    12001 taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact ccaaaggagc
    12061 ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag ctttggctca
    12121 gtttctatta tcgctcacat catccatcag aagattaatc tgaaggtacc caattatcgc
    12181 caagaagaag attgggctag gatggattta ccaatcacac gtaaggaaat ctctaattgg
    12241 catatcaagg caagtcaata ctatttagag tccctttata accttttacg agaaaagttg
    12301 ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggttctaga gagtgatagc
    12361 catctgacct actattggac ctttttgtct gggaaagctg agaatcaagc aatcacgctg
    12421 taccatcatg atcagcgtcg gagtggttta gtagtacaag aattcctagg agattattct
    12481 ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct ctagttctgc
    12541 ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt aaactgcgaa
    12601 ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg ggcacatgtg
    12661 agaaggaagt tttttgaagc gacccccaag caagcagata aatcatcctt agaagctaaa
    12721 ggtttagctt attgtgatca gttattttcc ctggaaagag actgggaggc tttgccagct
    12781 gatgaacgac tacagaaacg tcaagaagag ctccaacccc taatggaaga cttctttgct
    12841 tagtgccggc gtcagtcagt tttagcaggt tcaaaactag gaagggcaat tgaatacagc
    12901 ctcaagtatg aagaaacctt taagactatt ttgaaagacg gacatctggt cctttccaat
    12961 aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag agttcagtgg
    13021 actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc aaagttttga
    13081 aggagctaaa gcaacagcta ttattatgag tttgttggaa acagctaaac gtcatcaatt
    13141 aaatagcgag aaatatctat tctatcttct agaatgtctt ccaaacgagg aaactctcgt
    13201 aaacaaagag gttttagagg cttatttacc atggactaaa gttgtacaag aaaagtgcaa
    13261 ataagaaatc t
//
LOCUS       DAVMBH010000051        12590 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVMBH010000051 DAVMBH010000000
VERSION     DAVMBH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.051"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..1110
                     /gene="dnaN"
                     /locus_tag="VYP30_001742"
     CDS             <1..1110
                     /gene="dnaN"
                     /locus_tag="VYP30_001742"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1808695.1"
                     /translation="LFLQALNTTKRAISSKNAIPILSTVKIDVTNEGITLIGSNGQIS
                     IENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKS
                     EITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVL
                     SQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFA
                     NNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSAT
                     QNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNS
                     EKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            1175..1369
                     /locus_tag="VYP30_001743"
     CDS             1175..1369
                     /locus_tag="VYP30_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1808696.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1453..2568
                     /gene="ychF"
                     /locus_tag="VYP30_001744"
     CDS             1453..2568
                     /gene="ychF"
                     /locus_tag="VYP30_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1808697.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2639..3208
                     /locus_tag="VYP30_001745"
     CDS             2639..3208
                     /locus_tag="VYP30_001745"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1808698.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3209..6718
                     /gene="mfd"
                     /locus_tag="VYP30_001746"
     CDS             3209..6718
                     /gene="mfd"
                     /locus_tag="VYP30_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1808699.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGFGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            6786..7052
                     /locus_tag="VYP30_001747"
     CDS             6786..7052
                     /locus_tag="VYP30_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1808700.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            7045..7413
                     /locus_tag="VYP30_001748"
     CDS             7045..7413
                     /locus_tag="VYP30_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1808701.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7533..8801
                     /locus_tag="VYP30_001749"
     CDS             7533..8801
                     /locus_tag="VYP30_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1808702.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMAYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8798..10075
                     /gene="tilS"
                     /locus_tag="VYP30_001750"
     CDS             8798..10075
                     /gene="tilS"
                     /locus_tag="VYP30_001750"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1808703.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLTLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETAIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10079..10621
                     /gene="hpt"
                     /locus_tag="VYP30_001751"
     CDS             10079..10621
                     /gene="hpt"
                     /locus_tag="VYP30_001751"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1808704.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10637..>12590
                     /gene="ftsH"
                     /locus_tag="VYP30_001752"
     CDS             10637..>12590
                     /gene="ftsH"
                     /locus_tag="VYP30_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1808705.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         4333 a         1897 c         2565 g         3795 t
ORIGIN      
        1 ttatttctac aagcattaaa tactactaag agagctatta gttctaaaaa tgccattcct
       61 attttatcaa cagtaaaaat tgacgtgacc aatgaaggta ttactttaat tggttcaaat
      121 ggtcaaattt caattgaaaa ttttatttct caaaaaaatg aagatgctgg tttgttaatt
      181 acttctttag gttcgatcct tcttgaagct tctttcttta tcaatgtagt atctagttta
      241 cctgatgtaa ctcttgattt taaagaaatt gaacaaaatc aaattgtttt aaccagtggc
      301 aaatcagaaa ttaccctaaa aggaaaagat agcgaacaat atccacgaat ccaagaaatt
      361 tcagcaagca ctcctttaat acttgaaaca aaattactca agaaaattat taatgaaaca
      421 gcctttgctg caagtacaca agagagtcgt ccgattttaa caggtgtcca cttcgtattg
      481 agtcaacaca aagagttaaa aacagttgca acagactctc atcgcctaag ccagaaaaaa
      541 ttgactcttg aaaaaaatag tgatgatttt gatgtcgtaa ttcctagccg ttctctacgc
      601 gaattttcag cggtatttac agatgatatc gaagctgtag agattttctt tgccaataac
      661 caaatcctct ttagaagcga aaatattagc ttctatactc gtctcctaga aggaaactat
      721 cctgatacag atcgcttgat tccaacagac tttaacacta ctattacttt taatgtggta
      781 aacttacgcc agtcaatgga gcgtgcccgt cttttatcaa gtgcgactca aaatggtact
      841 gtgaaacttg aaattaagga tggggttgtt agcgcccatg ttcactctcc agaagttggt
      901 aaagtaaacg aagaaatcga tactgatcag gttactggtg aagatttgac cattagtttc
      961 aacccaactt acttgattga ttctcttaaa gctttaaata gcgaaaaggt gaccattagc
     1021 tttatctcag ctgttcgtcc atttactctt gtgccagcag atactgacga agacttcatg
     1081 cagctcatta caccagttcg tacaaattaa gtgaaagagg ttgagcctgg ctcgcctctt
     1141 ttatgatata atcgaaaaag aaaaggagag tagtatgtat caagttggaa attttgttga
     1201 gatgaaaaaa tcacacgctt gtacaatcaa gtcgactggt aaaaaggcta atcgttggga
     1261 aattacacgt gtaggagcag atatcaaaat aaaatgcagt aattgtgagc atgttgtcat
     1321 gatggggcga tatgattttg agcgaaaaat gaataaaatt attgactgag aacccttagt
     1381 tagagggtta gcactttatc cctttttgtg ttataatatt agggattgaa atgaaaacgg
     1441 agaatgagaa atatggcttt gacagcaggt atcgttggtt tgccaaacgt tggtaaatca
     1501 acactattta atgcaattac aaaagcagga gcagaggcag caaactaccc atttgcgact
     1561 attgatccaa atgttggaat ggtggaagtt ccagatgaac gcctacaaaa actaactgaa
     1621 atgataactc ctaaaaagac agttcccaca acatttgaat ttacagatat tgcagggatt
     1681 gtaaaaggag cttcaaaagg agaagggcta gggaataaat tcttggccaa tattcgtgaa
     1741 gtagatgcga ttgttcacgt agttcgtgct tttgatgatg aaaatgtaat gcgcgagcaa
     1801 ggacgtgaag acgcctttgt agatccactt gcagatattg atacaattaa tctggaatta
     1861 attcttgctg acttagaatc agtgaacaaa cgatatgcgc gtgtagaaaa gatggcacgt
     1921 acgcaaaaag ataaagaatc agtagcagaa ttcaatgttc ttcaaaagat taaaccagtc
     1981 ctagaagacg ggaaatcagc tcgtaccatt gaatttacag atgaggaaca aaaggttgtc
     2041 aaaggtcttt tccttttgac gactaaacca gttctttatg tagctaatgt ggacgaggat
     2101 gtggtttcag aacctgactc tatcgactat gtcaaacaaa ttcgtgaatt tgcagcgaca
     2161 gaaaatgctg aagtagtcgt tatttctgcg cgtgctgagg aagaaatttc tgaattggat
     2221 gatgaagata aaaaagagtt tcttgaagcc attggtttga cagaatcagg tgtagataag
     2281 ttgacgcgtg cagcttacca cttgcttgga ttgggaactt acttcacagc tggtgaaaaa
     2341 gaagttcgcg cttggacttt caaacgtggt atgaaggctc ctcaagcagc tggtattatc
     2401 cactcagact ttgaaaaagg ctttattcgt gcagtaacca tgtcatatga agatctagtg
     2461 aaatacggat ctgaaaaggc cgtaaaagaa gctggacgct tgcgtgaaga aggaaaagaa
     2521 tatatcgttc aagatggcga tatcatggaa ttccgcttta atgtctaaaa attaataaat
     2581 ggtgtcaatt aggttggaaa aaaattccaa cccttttggc ttttgaaagg aaaaataaat
     2641 gaccaaatta cttgtaggct tgggaaatcc aggggataaa tattttgaaa caaaacacaa
     2701 tgttggtttt atgttgattg atcaactagc gaagaaacag aatgtcactt ttacacacga
     2761 taagatattt caagctgacc tagcatcctt tttcctaaat ggagaaaaaa tttatctggt
     2821 taaaccaacg acctttatga atgaaagtgg aaaagcagtt catgctttat taacttacta
     2881 tggtttggat attgacgatt tacttatcat ttacgatgat cttgacatgg aagttgggaa
     2941 aattcgttta agagcaaaag gctcagcagg tggtcataat ggtatcaagt ctattattca
     3001 acatatagga actcaggtct ttaaccgtgt taagattgga attggaagac ctaaaaatgg
     3061 tatgtcagtt gttcatcatg ttttgagtaa gtttgacagg gatgagtata tcggtatttt
     3121 acagtctgtt gacaaagttg acgattctgt aaactactat ttacaagaga aaaattttga
     3181 gaaaacaatg cagaggtata acggataaat ggtgacctta ttagatttat tctcagaaaa
     3241 tgatcagatt aaaaaatggc atcaaaattt aacagataag aaaagacaac taatacttgg
     3301 tttatcaaca tctactaagg ctcttgcaat tgcaagcagt ttagaaaaag aagataggat
     3361 tgtgttattg atgtcaactt atggagaagc agaaggactt gttagtgatc ttatatctat
     3421 cttgggtgag gaactcgtct atccattttt ggtagatgat gctcctatgg tggagttttt
     3481 gatgtcttca caggaaaaaa ttatttcacg ggttgaagcc ttgcgttttt tgactgattc
     3541 atctaagaaa gggattttag tttgtaatat cgcagcaagt cgattgattt taccgtctcc
     3601 caatgcattc aaagatagta ttgtaaaaat ctcagttggt gaagaatatg atcaacacgc
     3661 gtttatccat cagttaaagg aaaatggcta tcgaaaagtt actcaagtac aaactcaggg
     3721 cgaatttagt cttcgaggag atattttaga tatttttgaa atatcccagt tagaaccttg
     3781 tcgaattgag ttttttggtg atgaaattga tggtatcagg tcatttgaag tagaaacaca
     3841 attatcgaaa gaaaataaga cagaactcac tatctttcca gctagtgata tgcttttgag
     3901 agaaaaggat tatcaacgag gacagtcagc tttagaaaaa caaatttcaa aaactttatc
     3961 acctattttg aaatcatacc tagaagaaat tctttcaagt tttcaccaaa aacaaagtca
     4021 tgcagactct cggaagtttt tatctttgtg ctatgataag acatggactg tctttgatta
     4081 tattgaaaaa gatactccaa tattctttga tgattatcaa aaattgatga atcagtatga
     4141 agtctttgaa agagaattag cgcagtactt tacagaagaa ttacagaata gtaaagcatt
     4201 ttctgatatg cagtattttt ctgatattga acaaatctat aaaaaacaaa gtccagtgac
     4261 ctttttttct aatcttcaaa agggtttagg aaatctcaaa tttgacaaaa tttatcaatt
     4321 caatcaatat cctatgcagg aatttttcaa tcagttttct tttctaaaag aagaaattga
     4381 acgatataaa aaaatggatt acaccattat tctgcagtct agcaattcaa tgggaagtaa
     4441 aacattggag gatatgttag aggaatatca gattaaattg gattctagag ataagacaaa
     4501 tatctgtaaa gaatctgtaa acttaataga gggtaatctc agacatggtt ttcattttgt
     4561 agatgaaaag attttattga taactgaaca tgagattttt caaaagaaat taaagcgtcg
     4621 ttttcgaaga caacatgttt caaatgcaga gagattaaaa gattacaatg aacttgaaaa
     4681 aggggactat gttgtccatc atatccatgg gattggtcaa tatctaggaa ttgaaaccat
     4741 tgaaatcaag ggaattcatc gtgattatgt cagtgtccaa taccaaaatg gtgatcaaat
     4801 ttctattccc gtggaacaga ttcatctact gtccaaatat atttcaagtg atggtaaagc
     4861 tccaaaactc aataaattaa atgacggtca ttttaaaaag gccaagcaaa aggttaagaa
     4921 ccaggtagag gatatagctg atgatttaat caaactctac tctgaacgta gtcagttgaa
     4981 gggttttgct ttctcagctg atgatgatga tcaagatgcc tttgatgatg ctttccctta
     5041 tgttgaaacg gatgatcaac ttcgtagtat tgaggaaatc aagagggata tgcaggcttc
     5101 tcagccaatg gatcgacttt tagttgggga tgttggtttt ggaaagactg aagttgctat
     5161 gcgtgcagcc tttaaagcag tcaatgatca caaacaggtt gtcattctag ttccgacgac
     5221 ggttttagcg caacagcact atacgaattt taaggaacga ttccaaaatt ttgcagttaa
     5281 tattgatgtg ttgagtcgct ttagaagtaa aaaagagcag actgcaacac ttgaaaaatt
     5341 gaaaaacggt caagtcgata ttttgattgg aacacatcgt gttttgtcaa aagatgttgt
     5401 gtttgctgat ttgggcttga tgattattga tgaggaacag cgatttggtg tcaagcataa
     5461 ggaaactttg aaagaactga agaaacaagt ggatgtccta accttgaccg ctacgccaat
     5521 ccctcgtacc ctccatatgt ctatgctggg aatcagagat ttgtctgtta ttgaaactcc
     5581 gccgactaat cgctatcctg ttcagaccta tgttttggaa aagaatgata gtgtcattcg
     5641 tgatgctgtc ttgcgtgaaa tggagcgtgg aggtcaagtt tactatcttt acaacaaagt
     5701 tgacacaatt gttcagaagg tttcagaatt acaggagttg attccggagg cttcgattgg
     5761 atatgttcat ggtcgaatga gtgaagtcca gttggaaaat actctattag actttattga
     5821 gggacaatac gatatcttgg tgacgactac tattattgag acaggggtgg acattccaaa
     5881 tgctaatact ttatttattg aaaatgcgga ccatatgggc ttgtcaacct tatatcagtt
     5941 aagaggaaga gtcggtcgta gtaatcgtat tgcttatgct tatctcatgt atcgtccaga
     6001 aaaatcaatc agtgaagtct ctgaaaagag attagaagcg attaaaggat ttacagaatt
     6061 gggctttggc tttaagattg caatgcgaga tctttcgatt cgtggagcag gaaatctttt
     6121 aggaaaatcc cagtctggtt tcattgattc tgttggtttt gaattgtatt cgcagttatt
     6181 agaggaagct attgctaaac gaaacggtaa tgctaacgct aacacaagaa ccaaagggaa
     6241 tgctgagttg attttgcaaa ttgatgccta tcttcctgat acttatattt ctgatcaacg
     6301 acataagatt gaaatttaca agaaaattcg tcaaattgac aaccgtgtca attatgaaga
     6361 gttacaagag gagttgatag accgttttgg agaataccca gatgtagtag cctatctttt
     6421 agagattggt ttggtcaaat catacttgga caaggtcttt gttcaacgtg tggaaagaaa
     6481 agataataaa attacaattc aatttgaaaa agtcactcaa cgactgtttt tagctcaaga
     6541 ttattttaaa gctttatccg taacgaactt aaaagcaggc atcgctgaga ataagggatt
     6601 aatggagctt gtatttgatg tccaaaataa gaaagattat gaaattttag aaggtctgct
     6661 gatttttgga gaaagtttat tagagataaa agagtttaag gaagaaaatt ccatttgata
     6721 tttttcttct ataaaataga taaaaataga taaaaatggt acaataataa attgaggtaa
     6781 taaggatgag attagataaa tatttaaaag tatcgcgaat tatcaagcgt cgtacagtcg
     6841 caaaggaagt agcagataaa ggtagaatca aggttaatgg aatcttggcc aaaagttcaa
     6901 cggacttgaa agttaatgac caagttgaaa ttcgctttgg caataagttg ctgcttgtaa
     6961 aagtactaga gatgaaagat agtacaaaaa aagaagatgc agcaggaatg tatgaaatta
     7021 tcagtgaaac acgggtagaa gaaaatgtct aaaaatattg tacaattgaa taattctttt
     7081 attcaaaatg aataccaacg tcgtcgctac ctgatgaaag aacgacaaaa acggaatcgt
     7141 tttatgggag gggtattgat tttgattatg ctattattta tcttgccaac ttttaattta
     7201 gcgcagagtt atcagcaatt actccaaaga cgtcagcaat tagcagactt gcaaactcag
     7261 tatcaaactt tgagtgatga aaaggataag gagacagcat ttgctaccaa gttgaaagat
     7321 gaagattatg ctgctaaata tacacgagcg aagtactatt attctaagtc gagggaaaaa
     7381 gtttatacga ttcctgactt gcttcaaagg tgataaaatg gaaaatttat tagacgtaat
     7441 agagcaattt ttgagtttgt cagatgaaaa gctggaagaa ttggctgata aaaatcaatt
     7501 attgcgttta caagaagaaa aggaaaggaa gaatgcgtaa attcttaatt attttgttgc
     7561 taccaagttt tttgaccatt tcaaaagtcg ttagcacaga aaaagaagtc gtctatactt
     7621 cgaaagaaat ttattacctt tcacaatctg actttggtat ttattttaga gaaaaattaa
     7681 gttctcccat ggcttatgga gaggttcctg tttatgcgaa tgaagattta gtagtggaat
     7741 ctgggaaatt gactcccaaa acaagttttc aaataaccga gtggcgctta aataaacaag
     7801 gaattccagt atttaagcta tcaaatcatc aatttatagc tgcggacaaa cgatttttat
     7861 atgatcaatc agaggtaact ccaacaataa aaaaagtatg gttagaatct gactttaaac
     7921 tgtacaatag tccttatgat ttaaaagaag tgaaatcatc cttatcagct tattcgcaag
     7981 tatcaatcga caagaccatg tttgtagaag gaagagaatt tctacatatt gatcaggctg
     8041 gatgggtagc taaagaatca acttctgaag aagataatcg gatgagtaaa gttcaagaaa
     8101 tgttatctga aaaatatcag aaagattctt tctctattta tgttaagcaa ctgactactg
     8161 gaaaagaagc tggtatcaat caagatgaaa agatgtatgc agccagcgtt ttgaaactct
     8221 cctatctcta ttatacgcaa gaaaaaataa atgagggtct ttatcagtta gatacgactg
     8281 taaaatacgt atctgcagtc aatgattttc caggttctta taaaccagag ggaagtggta
     8341 gtcttcctaa aaaagaagat aataaagaat attctttaaa ggatttaatt acgaaagtat
     8401 caaaagaatc tgataatgta gctcataatc tattgggata ttacatttca aaccaatctg
     8461 atgccacatt caaatccaaa atgtctgcca ttatgggaga tgattgggat ccaaaagaaa
     8521 aattgatttc ttctaagatg gccgggaagt ttatggaagc tatttataat caaaatggat
     8581 ttgtgctaga gtctttgact aaaacagatt ttgatagtca gcgaattgcc aaaggtgttt
     8641 ctgttaaagt agctcataaa attggagatg cggatgaatt taagcatgat acgggtgttg
     8701 tctatgcaga ttctccattt attctttcta ttttcactaa gaattctgat tatgatacga
     8761 tttctaagat agccaaggat gtttatgagg ttctaaaatg agggaaccag attttttaaa
     8821 tcattttctc aagaagggat atttcaaaaa gcatgctaag gcggttctag ctctttctgg
     8881 tggattagat tctatgtttc tatttaaggt attgtctact tatcaaaaag agttagagat
     8941 tgaattgatt ctggctcatg tgaatcataa gcagagaatt gaatcagatt gggaagaaaa
     9001 ggaattaagg aagttggctg ctgaagcaga gcttcctatt tatatcagca atttttcagg
     9061 agaattttca gaagcgcgtg cacgaaattt tcgttatgat ttttttcaag aggttatgaa
     9121 aaagacaggt gcgacagctt tagtcactgc ccaccatgct gatgatcagg tggaaacgat
     9181 tttgatgcgc ttgattcgag gaactcgctt gcgctatcta tcaggaatta aggagaagca
     9241 agtagtcgga gagatagaaa tcattcgtcc cttcttgcat tttcagaaaa aagactttcc
     9301 atcaattttt cactttgaag atacatcaaa tcaggagaat cattattttc gaaatcgtat
     9361 tcgaaactct tacttaccag aattggaaaa agaaaatcct cgatttaggg atgcaatctt
     9421 aggcattggc aatgaaattt tagattatga tttggcaata gctgaattat ctaacaatat
     9481 taatgtggaa gatttacagc agttattttc ttactctgag tctacacaaa gagttttact
     9541 tcaaacttat ctgaatcgtt ttccagattt gactcttaca aaagctcagt ttgctgaagt
     9601 tcagcagatt ttaaaatcta aaagccagta tcgtcatccg attaaaaatg gctatgaatt
     9661 gataaaagag taccaacagt ttcagatttg taaaatcagt ccgcaggctg atgaaaagga
     9721 agatgaactt gtgttacact atcaaaatca ggtagcttat caaggatatt tattttcctt
     9781 tggacttcca ttagaaggtg aatcaattca acaaatacct gtttcacgtg aaacagccat
     9841 acacattcgt catcgaaaaa caggagatgt tttgattcaa aatgggcata gaaaaaaact
     9901 cagacgttta tttattgatt tgaaaatccc tatggaaaag agaaactctg ctcttattat
     9961 tgagcaattt ggtgaaattg tctcaatttt gggaattgcg accaataatt tgagtaaaaa
    10021 aacgaaaaat gatataatga acactgtact ttatatagaa aaaatagata ggtaaaaaat
    10081 gttagaaaac gatattaaaa aagtcctcgt ttcacacgat gaaattacag aagcagctaa
    10141 aaaactaggt gctcaattaa ctaaagatta tgcaggaaaa aatccaatct tagttgggat
    10201 tttaaaagga tctattcctt ttatggctga attggtcaaa catattgata cacatattga
    10261 aatggacttc atgatggttt ctagctacca tggtggaaca gcaagtagtg gtgttatcaa
    10321 tattaaacaa gatgtgactc aagatatcaa aggaagacat gttctatttg tagaagatat
    10381 cattgataca ggtcaaactt tgaagaattt gcgagatatg tttaaagcaa gagaagcagc
    10441 ttctgttaaa attgcaacct tgttggataa accagaagga cgtgttgtag aaattgaggc
    10501 agactatacc tgctttacta tcccaaatga gtttgtagta ggttatggtt tagactacaa
    10561 agaaaattat cgtaatcttc cttatattgg agtattgaaa gaggaagtgt attcaaatta
    10621 gaaagaataa tctttaatga aaaaacaaaa taatggttta attaaaaatc cttttctatg
    10681 gttattattt atctttttcc ttgtgacagg attccagtat ttctattctg ggaataactc
    10741 aggaggaagt cagcaaatca actatactga gttggtacaa gaaattaccg atggtaatgt
    10801 aaaagaatta acttaccaac caaatggtag tgttatcgaa gtttctggtg tctataaaaa
    10861 tcctaaaaca agtaaagaag gaacaggtat tcagtttttc acgccatctg ttactaaggt
    10921 agagaaattt accagcacta ttcttcctgc agatactacc gtatcagaat tgcaaaaact
    10981 tgctactgac cataaagcag aagtaactgt taagcatgaa agttcaagtg gtatatggat
    11041 taatctactc gtatccattg tgccatttgg aattctattc ttcttcctat tctctatgat
    11101 gggaaatatg ggaggaggca atggccgtaa tccaatgagt tttggacgta gtaaggctaa
    11161 agcagcaaat aaagaagata ttaaagtaag attttcagat gttgctggag ctgaggaaga
    11221 aaaacaagaa ctagttgaag ttgttgagtt cttaaaagat ccaaaacgat tcacaaaact
    11281 tggagcccgt attccagcag gtgttctttt ggagggacct ccggggacag gtaagacttt
    11341 gcttgctaag gcagtcgctg gagaagcagg tgttccattc tttagtatct caggttctga
    11401 ctttgtagaa atgtttgtcg gagttggagc tagtcgtgtt cgctctcttt ttgaggatgc
    11461 caaaaaagca gcaccagcta tcatctttat cgatgaaatt gatgctgttg gacgtcaacg
    11521 tggagtcggt ctcggcggag gtaatgacga acgtgaacaa accttgaacc aacttttgat
    11581 tgagatggat ggttttgagg gaaatgaagg gattatcgtc atcgctgcga caaaccgttc
    11641 agatgtactt gatcctgccc ttttgcgtcc aggacgtttt gatagaaaag tattggttgg
    11701 ccgtcctgat gttaaaggtc gtgaagcaat cttgaaagtt cacgctaaga acaagccttt
    11761 agcagaagat gttgatttga aattagtggc tcaacaaact ccaggctttg ttggtgctga
    11821 tttagaaaat gtcttgaatg aagcagcttt agttgctgct cgtcgcaata aatcgataat
    11881 tgatgcttca gatattgatg aagcagaaga tagagttatt gctggacctt ctaagaaaga
    11941 taagacagtt tcacaaaaag aacgagaatt ggttgcttac catgaggcag gacataccat
    12001 tgttggtcta gtcttgtcga atgctcgcgt tgtccataag gttacaattg taccacgcgg
    12061 ccgtgcaggc ggatacatga ttgcacttcc taaagaggat caaatgcttc tatctaaaga
    12121 agatatgaaa gagcaattgg ctggcttaat gggtggacgt gtagctgaag aaattatctt
    12181 taatgtccaa actacaggag cttcaaacga ctttgaacaa gcgacacaaa tggcacgtgc
    12241 aatggttaca gagtacggta tgagtgaaaa acttggccca gtacaatatg aaggaaacca
    12301 tgctatgctt ggtgcacaga gtcctcaaaa atcaatttca gaacaaacag cttatgaaat
    12361 tgatgaagag gttcgttcat tattaaatga ggcacgaaat aaagctgctg aaattattca
    12421 gtcaaatcgt gaaactcaca agttaattgc agaagcatta ttgaaatacg aaacattgga
    12481 tagtacacaa attaaagctc tttacgaaac aggaaagatg cctgaagcag tagaagagga
    12541 atctcatgca ctatcctatg atgaagtaaa gtcaaaaatg aatgacgaaa
//
LOCUS       DAVMBH010000052        12382 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVMBH010000052 DAVMBH010000000
VERSION     DAVMBH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12382
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.052"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            206..3307
                     /locus_tag="VYP30_001753"
     CDS             206..3307
                     /locus_tag="VYP30_001753"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1808706.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGVK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYLIDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSLHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3390..4397
                     /gene="pfkA"
                     /locus_tag="VYP30_001754"
     CDS             3390..4397
                     /gene="pfkA"
                     /locus_tag="VYP30_001754"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1808707.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4456..5961
                     /gene="pyk"
                     /locus_tag="VYP30_001755"
     CDS             4456..5961
                     /gene="pyk"
                     /locus_tag="VYP30_001755"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1808708.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6225..6473)
                     /locus_tag="VYP30_001756"
     CDS             complement(6225..6473)
                     /locus_tag="VYP30_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1808709.1"
                     /translation="MQKANTKLEKPINQPLSSHIFRHTLLSTLAEKNAIMVRVEHKNA
                     KTVNNIYTHVSKRMEQATLEVLNTISLNRKYIRSNLDK"
     gene            complement(6640..6865)
                     /locus_tag="VYP30_001757"
                     /pseudo
     CDS             complement(6640..6865)
                     /locus_tag="VYP30_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7713..8585
                     /locus_tag="VYP30_001758"
     CDS             7713..8585
                     /locus_tag="VYP30_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1808710.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8731..9073)
                     /locus_tag="VYP30_001759"
                     /pseudo
     CDS             complement(8731..9073)
                     /locus_tag="VYP30_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9216..9527
                     /locus_tag="VYP30_001760"
     CDS             9216..9527
                     /locus_tag="VYP30_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808711.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            9531..10247
                     /locus_tag="VYP30_001761"
     CDS             9531..10247
                     /locus_tag="VYP30_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1808712.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10377..11192)
                     /locus_tag="VYP30_001762"
     CDS             complement(10377..11192)
                     /locus_tag="VYP30_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1808713.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11189..12094)
                     /locus_tag="VYP30_001763"
     CDS             complement(11189..12094)
                     /locus_tag="VYP30_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1808714.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         3880 a         2144 c         2630 g         3728 t
ORIGIN      
        1 ataatagata gggtataaaa gttctaggag atttatatta tatgctttct atttttatat
       61 acaatatagt ataaatataa aaacgatgac aaaaatacaa atgaatagaa aataaattag
      121 taagctgatg aaatttttct caagagaagc tatttatagg tgaaaatggt ataatatagt
      181 gagaaggata gaggagaagt gtaaattgat cgcacaacta gatacaaaaa cagtctatag
      241 ttttatggaa agcgtcattt cgatcgaaaa gtatgtgaga gcagctaaag aatacggcta
      301 cactcatttg gctatgatgg atattgacaa tctttatggc gctttcgact ttctagagat
      361 tacaaaaaaa tacggcattc atcctttgct agggcttgaa atgacagtgt ttgtagatga
      421 tcaggaagtg aatttgcgct ttttagctct atctagtgtg ggctatcagc agttgatgaa
      481 gctttcgaca gccaagatgc agggggtgaa aacttggtca gtcctgtccc agtacctgga
      541 ggatatcgcg gtcattgtgc cttattttga tagagttgag tcgttagaac taggctgtga
      601 ttactatata ggggtttatc cagaaacact agcaagcgaa tttcatcatc ctatcttacc
      661 tctttatcgg gtcaacgctt ttgaaagcag ggatagagaa gttcttcaag ttttaacagc
      721 gattaaagaa aatctaccgc tcagagaagt tcccttgcgt tcgagacaag atgtctttat
      781 atcagcaagt tctttagaga aactattcca agagtgtttt ccgcaagctt tggacaattt
      841 agaaaagctt atttcaggca tttcttacga cttggatact agtctgaaac tgcctcgttt
      901 taatccagct agaccagcag tagaggagtt gagagagcgt gctgaactgg ggcttgttca
      961 gaaggggttg actagtaaag aatatcaaga tagactagac caagaattgt ctgttattca
     1021 tgatatgggc tttgatgatt atttcttggt tgtttgggat ttgttgcgtt ttggacgatc
     1081 gaatggctat tatatgggaa tgggaagggg ttctgcagta ggcagtttgg tttcttatgc
     1141 cttagacatc acggggattg acccagtaga gaaaaatctg atttttgaac gctttcttaa
     1201 tcgtgaacgc tataccatgc ctgatattga tattgatatc ccagatattt atcgtccaga
     1261 ttttatcaga tatgttggta ataaatatgg tagtaaacat gcggcacaaa tcgttacttt
     1321 ttcaaccttt ggagccaagc aagctcttcg agatgttttg aaacgctttg gtgtgccaga
     1381 gtatgaatta tctgcaatta ctaagaaaat cagttttcgt gacaatctta agtcggccta
     1441 tgagggcaat ctccagtttc gtcagcaaat caatagtaag ttagaatacc aaaaagcttt
     1501 tgagattgct tgcaagatag agggctatcc aaggcaaacc tctgtccatg cggctggtgt
     1561 tgtaattagt gaccaagatt taaccaacta cattcctcta aagtatggtg atgaaattcc
     1621 actgactcag tatgatgctc atggagttga ggctagcgga cttttgaaga tggactttct
     1681 gggactacga aatttgacct ttgtccagaa gatgcaagag ttgcttgctg aaacagaagg
     1741 tattcatctg aaaattgaag aaatcgattt agaagacaaa gaaacgttag ctttatttgc
     1801 ctctggtaat acaaaaggta tctttcaatt tgagcaacca ggtgccattc gtctgcttaa
     1861 gcgtgtgcaa ccagtctgtt ttgaagatgt cgtcgcgact acttctctaa atcgaccggg
     1921 tgctagtgac tatatcaata attttgtggc aagaaagcat gggcaggaag aagtgactgt
     1981 tctggatcca gtactggagg atattttggc tccaacctac ggcataatgc tctatcagga
     2041 gcaggttatg caggttgccc agcgatttgc cggatttagt cttgggaaag ccgatatttt
     2101 gcgtcgggct atggggaaaa aggatgcctc tgccatgcat gagatgaggg cttcctttat
     2161 tcaaggttca ttagaagctg gtcatactgt ggaaaaagca gagcaggtct ttgatgttat
     2221 ggagaagttt gcaggctatg gttttaacag gtcacacgcc tatgcctact cagcattggc
     2281 cttccagttg gcttatttta aaacacatta tccagccata ttttatcaga ttatgttgaa
     2341 ttctgccaac agtgattact taatagatgc acttgaagca ggttttgaag tggcgcctct
     2401 gtccatcaac acgattccct atcacgataa aattgccaac aaggccatct atctaggttt
     2461 gaaatccatt aaaggagtca gtaatgattt agctctctgg attattgaaa atagacctta
     2521 ttctaacatt gaagatttta tagctaaatt acctgagaat tatctgaaac ttcctctgct
     2581 agaacctttg gtaaaagttg gtcttttcga ttcatttgaa aaaaatcgtc aaaaagtatt
     2641 taataactta gctaatctat ttgaatttgt gaaagagttg ggaagtttgt ttggagatgc
     2701 tatttatagt tggcaggaat cggaagattg gacggaacaa gaaaaatttt atatggaaca
     2761 agagctttta gggataggtg tcagcaaaca tccactacaa gctattgcaa gtaaggctat
     2821 ttacccgatt accccaatcg gaaatttgtc agaaaatagc tatgctatta ttttggttga
     2881 agttcagaaa ataaaagtga ttcgtaccaa aaagggtgaa aatatggcct tcttacaggc
     2941 agatgatagt aagaaaaaat tggatgtcac tctcttttca gacttatatc gtcaggttgg
     3001 acaggaaata aaagagggag ccttctacta tgtaaaagga aaaatacaat cacgtgatgg
     3061 ccgtctgcaa atgattgcac aagaaataag agaagcagtt gctgaacgct tttggataca
     3121 ggtgaaaaat catgaatcgg atcaagaaat ttcacgtatt ttagaacaat ttaaaggccc
     3181 aatcccagtc atcatccggt atgaagagga acagaaaacc atcgtttctc tccatcattt
     3241 tgtagctaaa tccaatgaat tagaggagaa attgaatgaa atcgttatga aaacgattta
     3301 tcgctaaaaa tacggaaaat agaagaattt taaaatcaaa tgtgatataa tcaagaagaa
     3361 tgttaaaaga aaaaggagca taaaccaata tgaaacgtat tgctgttttg actagtggcg
     3421 gagacgcacc tggtatgaac gctgctatcc gtgcagttgt tcgtcaagca atttcagaag
     3481 gaatggaagt gtttggtatc tatgacggat atgctggtat ggttgccggt gaaattcatc
     3541 ccctagatgc agcttcagta ggagacatca tttctcgtgg tggtactttt cttcactcag
     3601 ctcgttatcc agagttcgct caacttgaag ggcaacttaa agggattgag caattgaaaa
     3661 aacacggaat tgaaggtgta gttgttatcg gtggtgacgg atcttaccac ggcgctatgc
     3721 gtttgactga acatggcttc ccagctattg gtcttccagg tacaatcgat aacgatatcg
     3781 ttggtactga ctttacaatc ggttttgaca cagcggttac tactgccatg gacgctattg
     3841 ataagattcg tgatacatca tcaagtcacc gtcgtacttt tgtaatcgaa gttatgggac
     3901 gtaacgctgg tgatatcgct ctttgggctg gtattgcaac tggtgctgat gaaatcatca
     3961 tccctgaagc aggcttcaag atggaagata ttgtagcaag catcaaagct ggttatgaat
     4021 gtggtaaaaa acacaatatc atcgtcttag ctgaaggtgt gatgtcagcg gctgaatttg
     4081 gtcaaaaact taaagaagct ggagatacaa gcgaccttcg tgtaacagaa cttggacata
     4141 ttcaacgtgg tggttctcca actgcgcgtg accgtgtttt ggcgtcacgt atgggtgcac
     4201 atgctgttaa acttcttaaa gaaggtatcg gtggtgttgc ggttggtatt cgtaacgaaa
     4261 aaatggttga aaatccaatt cttggtactg cagaagaagg ggcattgttt agccttactg
     4321 cagaaggtaa gattgtggtt aacaacccac acaaagccga tattgagcta tctagcttga
     4381 ataagagctt gtcataattt acaatttagt taataagacc aaaaaggtca tatatataaa
     4441 ggagtcacaa aaatcatgaa caaacgtgta aaaatcgttg caactttggg tcctgcggta
     4501 gaaatccgtg gtggtaaaaa attcggtgag gacggatact ggggtgaaaa acttgatgtt
     4561 gaagcttcag ctaaaaacat tgctaaattg attgaagctg gtgctaacac attccgattc
     4621 aacttctcac acggcgacca ccaagaacaa ggtgagcgta tggcaactgt taaacttgcg
     4681 gaaaaaattg caggtaaaaa agttggtttc cttcttgata caaaaggacc tgaaatccgt
     4741 acagaattgt tcgaaggtga agctaaagaa tattcataca aaactggtga aaaaattcgt
     4801 gttgcaacta aacaaggaat caaatcaact cgtgaagtga ttgcgttgaa cgttgctggt
     4861 gctcttgata tctatgatga tgttgaagtt ggtcgtcaag ttttggttga cgatggtaaa
     4921 cttggtcttc gtgtggttgc taaagatgat gcaactcgtg aatttgaagt tgaagttgaa
     4981 aacgatggta tcatcgctaa acaaaaaggt gtgaacatcc ctaacactaa aattcctttc
     5041 ccagctcttg ctgaacgcga taacgacgat atccgtttcg gtcttgaaca aggtatcaac
     5101 ttcatcgcaa tttcattcgt acgtactgca aaagatgtga acgaagttcg tgcaatctgt
     5161 gaagaaactg gaaacggaca tgttcaattg ttcgctaaaa tcgaaaacca acaaggtatc
     5221 gataacttag acgaaatcat cgaagcagct gatggtatta tgattgctcg tggtgatatg
     5281 ggtatcgaag taccgttcga aatggttcca gtttatcaaa aaatgattat caagaaagtc
     5341 aatgctgcag gtaaagttgt tatcactgca acaaacatgc ttgaaacaat gactgaaaaa
     5401 ccacgtgcaa ctcgttcaga agtatcagac gtattcaacg ctgttatcga cggaactgac
     5461 gctacaatgc tgtcaggcga gtctgcaaac ggtaaatacc cactcgagtc agtaactaca
     5521 atggctacaa tcgacaagaa cgctcaagct cttcttaatg aatacggacg tcttgattca
     5581 gattcatttg agcgtaactc taagacagaa gtaatggctt ctgctgttaa agatgctact
     5641 agctcaatgg atatcaaatt ggttgtaact cttactaaga caggtcatac tgcacgtttg
     5701 atttctaaat accgtccaaa tgctgacatc ttagcattga catttgacga attgacagaa
     5761 cgtggcttga tgttgaactg gggtgttatc ccaatgttga cagatgctcc atcttcaact
     5821 gacgatatgt tcgaaatcgc tgaacgtaaa gcggtagaag caggtctcgt tgagtcaggc
     5881 gatgatatcg ttatcgttgc tggtgtgcca gtaggagaag ctgttcgcac aaacacaatg
     5941 cgtatccgca cagtacgtta agaaaaatat aaaaacctat catatccagc tttctagcct
     6001 gtatgatggg ctcttttttt gtccaggggg caaaactttc ataatggatt gatactcttc
     6061 gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta ctcaagtaca gcttgcggct
     6121 agcttcctag tttgctcttt gattttcatt gagtatgaaa taagatatgt acaaattgat
     6181 tagaaagtca aatgaatttc tacaaatgtt ttagcaatcg caatctactt gtctagattc
     6241 gatctgatat attttcgatt taatgatatg gtatttaaaa cctccaaagt agcttgctcc
     6301 attcttttac ttacgtgagt gtagatgtta tttactgttt tagcgttttt gtgttccact
     6361 ctaaccatta tagcattctt ctcagctagt gtactaagga gtgtgtgcct gaaaatatgg
     6421 gaactaaggg gctggtttat cggtttctct agtttagtat ttgccttttg caaagtgatc
     6481 ttaaaagcct ttctctaaat ttacatatca ctattgttta acaaaatcta atctatttta
     6541 ggtcacttat tctttttttg aaatgtagaa tgaacttttt caaagttttt cgaatctttt
     6601 aaaatctgtt tgttttatat cgccattctc cccccttttt taattctccc tatatagcct
     6661 gacaactttc ccgatggtac gaatatggtt gctttcgtct aggtggatgt cggggtattc
     6721 gggattgagt ttttttgagg tagccttggc ggagtttctt gacatagtta gcgccgtcta
     6781 cttggaagat gccgatggta ttatagtcaa tctgtggggt attcttgata aataggtagt
     6841 cgctgtttct tatctttgcc tccatggact tgctgacgac ataagcgatt gggtcgtagt
     6901 cgtctgggat aatggaaact ccataactaa atcgtcgtcc tgcatcgagc ggctacctgc
     6961 agagataaac tacctaacac gagagtaagt agtctgtctg tagtcgtcca gtctgatgat
     7021 ttttacgata cttcgttttt ctgcttatac agttgcctct aggcataggt taggacttta
     7081 ccttgtctgg gtggtgcccg ttggtcgtag atagattgga tatcgctagg agaatccttt
     7141 tgaactggag gaaagagggc atcaatcaag ctactgaata ctttaactaa gtcaaatata
     7201 gtatttttct tagtagacct aacccttttt tcataatttc taatggtgtt tttacttata
     7261 cctatcttag tacccaattc ttattgagtc caaccattac tagtctatat tgttttatag
     7321 ttgattgagt ttggaatagt acgctgtagc tgctaaaaca tttctaggaa ttaatttgcc
     7381 tttcctaata gagttgttca tatcttattt caatctatta tatttttcgc ctctaacaat
     7441 cgcaatctct tctttatcta cgaacgaaat cgctttctat ttttgtaagt aaagcatcac
     7501 acgaaatcca cgaaaatgaa aacctttgtt gtgttttcgt aaaaaatttg ttgacagagc
     7561 acgaaacgcc tactataatt aaatcaagtt taaggaaata acaaaaaaac aaatcggagg
     7621 gaaagacgat gaacacatta aatgagaaag taatcaatat ctgtaaagca gtagttaaag
     7681 aaactttaat ccaagacatt taggagaaag aaatgaagaa atcaagaaaa ttagccacat
     7741 taggaatctg ttcagccttg tttttaggct tggctgcttg tcaacaacaa catgctactt
     7801 ctgagggtac gaatcaaagg caaagcagtt cagcgaaagt tccatggaaa gcttcataca
     7861 ccaacctaaa caaccaggta agtacagaag aggtcaaatc tctcttatca gctcacttgg
     7921 atccaaatag tgttgatgca ttttttaatc tcgttaatga ctataatacc attgtcggct
     7981 caactggctt atcaggagat ttcacttcct ttactcacac cgaatacgat gttgagaaaa
     8041 tcagtcatct ctggaatcaa aagaagggcg atttcgttgg gaccaactgc cgtatcaata
     8101 gttattgtct tttgaaaaat tcagtcacca ttccaaagct tgaaaagaat gaccagttgc
     8161 ttttcctaga taatgatgcg attgataaag gaaaggtctt tgattcacaa gataaggaag
     8221 agtttgatat tctattttcg agagttccaa ctgaggcaac tacagatgtc aaggttcacg
     8281 ctgaaaagat ggaaacattc ttctcacaat ttcaattcaa tgaaaaagct cgaatgctgt
     8341 ctgtagtctt gcacgacaat ctggatggcg agtatctgtt tgtaggccac gttggggtct
     8401 tagtacctgc tgatgacggt ttcttatttg tagagaaatt gactttcgaa gagccctacc
     8461 aagcgattaa atttgctagt aaggaagatt gctacaagta tttgggcacc aagtatgcgg
     8521 attatacagg cgagggactg gctaagcctt ttatcatgga taatgataag tgggttaaac
     8581 tttaatagtg ttatgatatg acagtaatct taggattttt atttctattt ttgataagtt
     8641 ggtgggttat ttcaatcgtt aatagccaga aaccacgcaa aaatgaaaca tttattggct
     8701 atgtccaaag atacgatatt gatgggaatg gctatcaatc attaccgtgt cctcagaact
     8761 gagaggagtt cttgaaatcg taaaaccact ttgaacaaga gttacttcaa cccattggct
     8821 ccgacggatt aagttgcttt cgtgaatacc aagatcagcc gcaatttctt cataagtgcg
     8881 gttctcacac atattgaaga gtggccataa gaaggtcttc taggcttaat ttaggttttc
     8941 gtccaccttt tgcgtgttta agttgataag ctgtttttaa tacagctaac atctcttcaa
     9001 aagtggtacg ctgaacacca acaagacgtt taaatcgtgc atcagttagt tgtttacttg
     9061 cttcataatt catagaacta ctataccata ttttgtttcg caggaagtct aatgctaaaa
     9121 tcttatcagt gagaagattt cttaaagttt attctttgta gtttcatctg tattagtaca
     9181 taatttaact tagagaaaat aggaggacta atcgaatgga attaaaagat tttacagaaa
     9241 aagaacagga aatgattaag aaaaggctta caatgtctaa tattagtgac aaagaaacta
     9301 ctgagaagat tctggcgcta gtcccacaag acttgattaa gcgaatcccg ttttttgtca
     9361 gaaaacatgc tacaacacgt acgattaaac gcatttcaat tgaataccct gaactctacg
     9421 ctgtagctca aacaagtggt gagattccag aaaaaaaacg cgaagaattg cgtcagatta
     9481 tcacaactat ctttgaacaa aagatgaata agcatagtat taagtagaga atgaaaaaat
     9541 attttattgg cggtttggga agcaatgcct atcatagcaa ggattttctt caagaactag
     9601 attcgcaggt ctattttcta aatccatatg aaaagcatct tcgagatgaa acagaattga
     9661 aatcatggtt taaaaatgag attgtagagg aagaatctat ctgtctgata ggtcattcta
     9721 ttggaggcga tttagctcgt tatttcgcat cggaatttga agaagtaaag aaactgattc
     9781 ttttggatgg tggctatcta gatttagata agattttacc tttggataca gagttagagg
     9841 aaactaaaaa ttatatcaaa tctcaaatta tttcggactt agatgttctt acttctaaag
     9901 aaaaatctga agcaaagcat tggtcagaaa atatggagaa agctgtaaga cagtcctatc
     9961 actggaatgt tgagtataat agatatgagt tggctataaa ttatgaaaat atagaagcga
    10021 tactccgcct acggagaaaa atacaagctt ttaagagaga agtgggagat accttgttta
    10081 ttagtcctcg ctatcctaat gaagctacat ggagagagga agccctaaaa gaattgccag
    10141 actattttga tactattttt ttagaaaact ttggccatga gctttatact caagcaccta
    10201 aagaaatcgc tagtctaatg aatgagtggc tcgcttattt tctatgagct acttgtattg
    10261 ctggaaatgg tataagatga aaatctacaa gtcactaatt ttcatataac caaaaaacga
    10321 acaggctctt tttctgttat tcagaagaga acttgttcgt ttttatcttg attttcttaa
    10381 aaagctctat atacataggg attttctggt ttatcgactt tggtaaagct gtcgatttcc
    10441 aaggttggaa ggttttgttt gagttcttta tggtagtgat tgaccagttt tcctttggct
    10501 gaaatccaag tgttgttttc atactgccgg gtattgccct tggtcagcaa tccatagaca
    10561 ccagaatctg cgatgcagtg aataatgccg aagcggaaca gaaattggct attggcatga
    10621 ctggggtcat tatagacaaa gcctgtgaac tggattgtct taccctcaaa ttcatctgga
    10681 tagtcgtaga tagcctccat gacctccata tagttttcat tagtgatctg aatactatct
    10741 tgggataagt atttatccgc cgccgttcgc atttcctttt cataggctga ttttgaaaaa
    10801 taagaactgg tatctggttt caaatattgg cttgtcgtcc cttcgcttgt ctgaatggct
    10861 agatccgttc cttccgatag ggggaaatga taacctttag cagaaacggt ctgagaatcc
    10921 aagctaacag ttgggaaagt taagccgatg acaagtggaa tagccagaag agaaatactc
    10981 gtcatcttgg ctaatcggct gttcagatga ctgtgggttt tgacttgctt catccagata
    11041 tacaattgaa cgatagccaa gataaaagaa agcaccatgg agatataggc cagataggaa
    11101 tagtgcatgt tgatgtactg gtttagtttg cccgacagat ggaggtaaat agtcagttca
    11161 aaatagccag ctaaaactaa aaatcgaatc ataggatgac tccaatcaag agagaataga
    11221 ctaagacgac aagagttaca attgttatga agtgactgat aaatcgtgct ttcaagtaat
    11281 ttttcatcat gagaatattt ttgatatcca gcattggacc aatgacgaga aaggccagaa
    11341 ctggtgccaa accgaaactc gagagaagag aagcacctat aaaggcatcc gcctcactac
    11401 agagcgaaag aagaaaggct aaaatcatca agagcaggat ggcaaaaaga ggggtcgcac
    11461 tgatagaggt cagaatccga gtcggaacgt agacctgtat tatagaagca aagaggcagc
    11521 caaataccaa ataacgcccc gtatcaaaaa attcatcaat ggcctgcaca aagacttgaa
    11581 aaactttttt tgcagaactc aagtaagaaa aatcatgctc atgacaagcc agacgatttt
    11641 ctttctgaat cggttcttgc cagaaaaatc ctagaaaaat tcctagtatt acagccacaa
    11701 gaatggaacc cagagctcgt aatagggcga catggaagga gttgccaaag gcagaatagg
    11761 tcgcaaaaag aacaatggga ttgataacag gtgctgtcac aagaaaagga acggccgtgt
    11821 aacttggaac ctttttttcc agaaaacgat tgatgatggg gacgattcca cattcacaag
    11881 aagggaaaaa cataccgacg aaggtcccaa aaaagattct cccccaacga tttcgaggga
    11941 gaaaatgata aaccttgtca ggtgtgatat aaacttcaat cagccctgag acaatgcttc
    12001 ctatcagaac gaagggaagg gcttcaatga taatggagag aaaaatggct ccagtttgaa
    12061 gtacactaga tgggagttgt tgaaaagcag tcatctagtt tttcttttct gctttggctt
    12121 ttttctcttt gtcatcaggg aaagtaactt gtttcaaatc agggagttta gcaaactctt
    12181 caaacatctt gtccaagtcg tctcgttttg taaatttgac agccataggt gtacctcgat
    12241 tctaaattct acctctatta tactattatt ttgcggaaaa gggagttttt taatttgttt
    12301 tcgatagttg atacacttcg aaaatctctt caaaccacgt cagcttcgcc ttaccgtagt
    12361 acggttactg acttcgtcag tt
//
LOCUS       DAVMBH010000053        12157 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVMBH010000053 DAVMBH010000000
VERSION     DAVMBH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.053"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VYP30_001764"
     CDS             complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VYP30_001764"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1808715.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            856..1416
                     /locus_tag="VYP30_001765"
     CDS             856..1416
                     /locus_tag="VYP30_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1808716.1"
                     /translation="MTWIILGVIALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLKKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1418..2317
                     /gene="htpX"
                     /locus_tag="VYP30_001766"
     CDS             1418..2317
                     /gene="htpX"
                     /locus_tag="VYP30_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1808717.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(2361..3920)
                     /locus_tag="VYP30_001767"
     CDS             complement(2361..3920)
                     /locus_tag="VYP30_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1808718.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGIGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(4335..4475)
                     /locus_tag="VYP30_001768"
     CDS             complement(4335..4475)
                     /locus_tag="VYP30_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blpT protein"
                     /protein_id="HEV1808719.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQVTADDIRLQELLNTTMQELKKQ
                     KS"
     gene            4645..5187
                     /locus_tag="VYP30_001769"
     CDS             4645..5187
                     /locus_tag="VYP30_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1808720.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            5187..5816
                     /gene="nth"
                     /locus_tag="VYP30_001770"
     CDS             5187..5816
                     /gene="nth"
                     /locus_tag="VYP30_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1808721.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            6027..6548
                     /gene="pyrR"
                     /locus_tag="VYP30_001771"
     CDS             6027..6548
                     /gene="pyrR"
                     /locus_tag="VYP30_001771"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1808722.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            6567..7490
                     /locus_tag="VYP30_001772"
     CDS             6567..7490
                     /locus_tag="VYP30_001772"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1808723.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            7540..8619
                     /gene="carA"
                     /locus_tag="VYP30_001773"
     CDS             7540..8619
                     /gene="carA"
                     /locus_tag="VYP30_001773"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1808724.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            8932..12108
                     /gene="carB"
                     /locus_tag="VYP30_001774"
     CDS             8932..12108
                     /gene="carB"
                     /locus_tag="VYP30_001774"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1808725.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPVQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLETGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         3470 a         2395 c         2693 g         3599 t
ORIGIN      
        1 aaataagaga gcgaggttga ttttgtaaat atttttttac ttaaaaattt aaagcgggcg
       61 tttatttggc ataccagcct tacgtggata tttatttggt gtttcttttt tcttttctac
      121 cactgtgatg taacgcggat ctctatttgg tagggcgtag ctgagattgt cttcgacttt
      181 actaaaaagg agattgaggg cattcttagc ttctaacaac tcctcaggcg cattgctggc
      241 cttgagtgcc aatagttttc caccaacctt aaggtaggga atagtcaatt cagataggac
      301 ctgcatacgg gcaaccgcac gagctgttac aaaatcatat tgagcacgga agttcttgtc
      361 ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact ccgttcaaat ccagttcttg
      421 agccaagagt tgtaggaagt tgatgcgctt attgagtgaa tcaataatgg tcacatctaa
      481 ctccggatag agaattttca ttggtagact aggaaatcct gccccagccc cgatatcaag
      541 aagtttgata gtttcattgg gaatcaaacc ttgaagaatg ggtgcaatcg aatcgtaaaa
      601 atgtttgaga taaacttctt ccttgtccgt aatcgccgtc aaattaatct tctcattcca
      661 ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt tgctggtccg aaagtggaag
      721 attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc atagttattt ccttctttag
      781 tatcatctta ttttaccaca atcatagaaa atttgatata ctggtactaa tctaaaagca
      841 gaaaggactt atattatgac ttggattatt cttggagtta tcgctcttgt tgttattttt
      901 gtgattgtta gctataacgg tttggttaaa aatcgtatgc aaaccaagga ggcttggagt
      961 cagattgatg ttcagttgaa acgtcgcaat gatctcttgc caaacttgat tgagactgta
     1021 aaaggttatg ccaaatatga aggttctacc cttaaaaagg tggcagaact acgtaaccaa
     1081 gtggcggcag cgacttcacc agcagaagct atgaaagcca gtgatgccct cactcgtcag
     1141 gtttcaggta tttttgcagt tgcagaaagc tatccagatt tgaaagctag tgctaacttt
     1201 gttaaattgc aagaggagtt gacaaacaca gaaaataaaa tttcttactc tcgtcaactc
     1261 tataacagtg ttgtcagcaa ctacaatgta aaattagaaa ctttcccgag caatattatc
     1321 gctggaatgt ttggatttaa agcggcagat ttccttcaaa cacctgaaga ggaaaagtcg
     1381 gttcctaaag ttgattttag cggtttaggt gactaagatg ttgtttgatc aaattgcaag
     1441 caataaacga aaaacctgga ttttgttgct ggtatttttc ctactcttag ctcttgttgg
     1501 ttatgcggtt ggttatctct ttataagatc tggacttggt ggtttggtta tcgcactgat
     1561 tatcggcttt atctacgctt tgtctatgat ttttcaatcg acagagattg tcatgtccat
     1621 gaatggagcg cgtgaggtgg atgagcaaac ggcaccagac ctctaccatg tagtggaaga
     1681 tatggctctg gtcgcccaga ttcctatgcc ccgtgttttc atcattgatg atccagcctt
     1741 aaatgccttt gcgacaggtt ctaatcctca aaatgcggct gttgctgcga cttcaggtct
     1801 actagctatc atgaatcgtg aagaactaga agctgttatg ggacatgaag tcagtcatat
     1861 tcgtaattat gatatccgta tttcgactat tgcagttgcc cttgctagtg ctatcaccat
     1921 gctttctggt atggcaggtc gtatgatgtg gtggggtgga gcaggtcgca gacgaagtga
     1981 tgatgaccga gatggaaatg gtcttgaaat cattatgcta gtggtttccc tactagctat
     2041 tgtactggca cctctcgctg caaccttggt tcagctcgct atttctcgtc agagggaatt
     2101 tctggcagat gcatctagtg tcgagctgac tcgcaatccc cagggaatga ttaatgccct
     2161 agataagttg gacaatagta aacctatgag tcgccacgtc gatgatgcta gcagtgctct
     2221 ttatatcaat gatcccaaga aaggtggggg gttccaaaaa ctcttttata cccacccacc
     2281 tatctcagaa cggattgaac gtttaaaaca gatgtaaaag aatccagagg tcgtctctgg
     2341 atttttgcta tgttgcaaat ttatacatct tctaaattaa ctaactccaa accgtgttct
     2401 gtcaagcggt agatgcttga acagacctct tttaagaaac gacggtcatg cgaaacagtg
     2461 atgagaccgc ctggataggt tgcaaagagt tttctgattt ggggttgaga agtgggagaa
     2521 aagtttcgtg tgggttcatc cagcaggaga aagtttggtt tgcgcaggac taaatccaaa
     2581 agcaggagtt ttccctgttg tccgccagat aaggagcgaa tttgatgctg catttctgga
     2641 taactgaaat tgagactggc taggtgagat tggattttct gaagttcctc tttttcccca
     2701 gttttgctga tataagctat tgaggataaa tccaattgca gttttttgtg gtaatcttgt
     2761 ggcataaaac caagtgaaat ctctctttta tcattaagaa gttgctgtaa tttggctaac
     2821 agagttgatt tcccaatacc atttgggccg atgataccga ttttttcttg gccacggaca
     2881 gttagttgca gttcctgagc caaaacacgg tcgtcaatgg acaaattttc tttttccagt
     2941 tggactaaga ctttagaagc tggtaatggt tggatgtctg aaaagaaaag ttggatttgt
     3001 tcctcttcaa gtggcttttg agtcatggac tgagctgtct tttcgtagcg tttttcttgt
     3061 gagaggacag ttttcatctt tttagccaat aggcgaccgg cagtactatc tttggtagct
     3121 cgaagcgcag tttctacatt ttgcttaact ctccgatgtt tttccatggt tttatcgtag
     3181 gctctttggt tgttagcagc ttgctgactt tgtttggcaa aattagcctt tctctgctca
     3241 ctatagctat catagtctaa atgctctact agcgtttccg cttctttacg gtgtttgacc
     3301 agtcgcaagt ggacaatagt gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg
     3361 aaaataacgg tttgcctggt cttttgaatc tggcctttta gccaatcaac tgtctcaagg
     3421 tctaggtcat ttgaaggttc atctaaaaat agaatctcaa agggtttggc taactcatgg
     3481 ataagctgaa ttttcaaagc ttcgccccct gatagattgc caatctcttg gtcacttgcg
     3541 aaacgattgc tatcaaaatg caattcctcc gccaaacgat agaggatact gtagtctaaa
     3601 tcaatagaat ctaaaaagaa gtagtcgtgt aaagttttct tttttaggtc ctcagggact
     3661 ttttgaggaa tgtaggccag tgactgataa tcagactgga tgtctccctt gatagtgaaa
     3721 tcagacaaat cttcccccat taaagtttta agtaaggttg atttaccatt tccttcttcg
     3781 ccaataatag ctaccttttc cccgtcttgt atggtcatgc ttaggtcaga gacaaggtct
     3841 cgtaaatctt tgttttgtgt gatggtcagg tgattgattt ttatcatatg atttcccttt
     3901 ctagaatgtt catagtgcat aacaaaaagc tctactttac ctagtagagc ccaaagtcta
     3961 tgtcaaaaaa actctattaa catgccagaa aaagagcata aaagagcaca caaaaagaga
     4021 caaaaacaag atctactaaa taaaggttct ttatttgata gacttagttg ttcatgtctc
     4081 ccttacctcc gagtattagt atctttatat tataccttta aggaaatttt gtcaacagaa
     4141 aactggaaat tctatgctct aaaatccaaa aacaggtcca tagagactta gtacgtgttt
     4201 gacatactcg taatggattt tatcatagtt tcgccaagca gtgcgtgctt gattgtttag
     4261 ttttaggcta cccagtccaa tcagaggact ggtgggttgg taaaatttct caagattaat
     4321 taagatactg ttgttcaact tttctgtttt ttgagctctt gcatagtagt gtttagcagc
     4381 tcttgtagtc gaatatcatc tgccgtaacc tgtttacagt tttggtagct tttatttaac
     4441 ttggatagga gttgaatgag tttcttgtct tccatgtgag catcctcctt gatctgatgt
     4501 actctttccc tatagtatag cactaaaaaa taaaactatc atagtaaata tgttaaaatt
     4561 ttgaatttta attacaaagt ttggtgtgct gatttgtagc cttttcatgg tataatcaag
     4621 agagtaaatc tttatggagg aagtatgaaa ttaaatattc aagaaattcg taagcagtct
     4681 gaaggtttga actttgaaca aacgttagat ttagttgatg acctgcgtgc acgtaatcaa
     4741 gaaattttag atgtaaaaga tatccttgca gttgggaaag tacaatatga agaccgtatg
     4801 tatttcttag attatcaact atcttatacc attgttcttg cttcgagtcg cagtatggag
     4861 ccagttgagt tagttgaatc ttatccagtc acggaagttt tcatggaagg cgcaactaac
     4921 cagctagatc aagaagtttt agatgatgac ttggtcttgc ccatcgaaaa tggggcgctt
     4981 gaccttgctg agagtgtatc agacaatatc ctgctaaaca ttcctatcaa ggtcttgacg
     5041 gctgaagaag aagctggtca aggatttgtc tcaggaaatg actggcaaat catgacagag
     5101 gaagaatacc aagctcaaca agcagtaaag aaagaagaaa acagtccttt tgctggctta
     5161 caaggactat ttgacggaga tgaataatgg tcttgtcaaa aaaacgagca cgaaaggtgc
     5221 tagaagaaat cattgccctc ttcccagatg ccaagcctag tcttgatttt accaatcatt
     5281 ttgaactcct ggttgcggtc atgttatcag cccagacgac agatgcagcg gtaaataagg
     5341 ccacaccagg tctctttgtt gcctttccaa caccccaagc tatgtctgta gcgacagaga
     5401 gtgagattgc ttcacatatt tctcgcttgg gattgtatcg gaataaagct aaattcctta
     5461 aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca agtccctcag acacgtgaag
     5521 aattggagag tttggcaggt gttggtcgca agacagccaa tgttgtcatg agtgtaggat
     5581 ttgggattcc agcctttgca gtggatactc atgtggagcg tatttgcaaa caccacgata
     5641 ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg ggtcatggat atcttgccgc
     5701 ctgagcagtg gttagctgcc catcaggcca tgatttattt tggaagagcc atttgccatc
     5761 caaaaaatcc agagtgtgac cagtacccac aattatatga ttttagcaat ttgtaagatg
     5821 ctacattgaa actttttgct tgattttaag catgctttgt gctatagtaa atgataacta
     5881 aatattcctt taaacctgtc ccgtgaggca ggcaaggagc gcgataaagt agaagggtga
     5941 agtctatact gtgttcagta gggctcgctt ggctataaat ttcaagtctc cttgtttaag
     6001 gagacttttc tttttggagg tttgtcatga aaacaaaaga agttgtagac gaattgaccg
     6061 tcaaacgagc gattacgcgt attacttatg agattatcga acgcaacaaa gatttgaata
     6121 agatcgtctt ggctggtatt aaaactcgtg gtgtctttat tgcccaccga atccaagaac
     6181 gtttgaagca gttagaaaat ctttcagttc ctgttgtgga attggatact aaacctttcc
     6241 gtgatgatgt taaaagtgga gaagatactt ctttggtttc tgtcgatgtg acagaccgcg
     6301 aagttatctt ggtggatgat gtgctctata caggtcgtac catccgtgct gctattgata
     6361 atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc agttctagtc gatcgtggac
     6421 atagagaatt gccaatccgt ccagattacg ttggaaaaaa tatcccaacc agtcgttctg
     6481 aagaaatcat cgtagagatg acagaacttg atgaccaaga cagagttctg attactgaag
     6541 aagcttagaa agttaaagga gtagccatgt cagaaaatca acaagcattg aaccatgtgg
     6601 tgtccatgga agacctcact gtcgatcaag taatgaaatt gatcaagcga ggaattgagt
     6661 ttaaaaatgg agcccagctt ccctatgaag accatccgat tgtttccaat ctcttctttg
     6721 aggattctac acggacacat aagtcctttg aagtcgcaga gattaaactt ggattggaac
     6781 gacttgactt tgatgtgaag actagctcgg ttaataaggg tgagacactt tatgacacca
     6841 ttttgactct gtctgcttta ggagtggatg tctgtgtgat tcgccatcca gaggtcgact
     6901 actatagaga attgattgct agtccaacga ttacgacttc catcatcaat ggtggagatg
     6961 gttcgggcca acaccctagc cagagcttgc ttgatttgat gaccatttat gaggaatttg
     7021 gccactttga gggtcttaaa gttgctattg caggtgactt ggaccactca cgcgttgcca
     7081 aatccaatat gcagattttg aaacgcttgg gagctgaact ctttttcgct ggacctgagg
     7141 aatggagaag tcaagagttt gcagactatg gaaagtttgt aaccattgat gaaatcattg
     7201 atcaggttga tgtcatgatg tttctccgtg tgcaacacga acgccatgat agtggagctg
     7261 tattttcaaa agaagactac catgcccaac atggcttgac tcaagaacgt tacgatcgtt
     7321 tgaaagaaac agcaatcctc atgcacccag ctccaatcaa tcgtgatgta gaaatagcag
     7381 accacttggt tgaagcacca aaatcacgga ttgtccaaca aatgaccaat ggtgtctttg
     7441 ttcgaatggc aatcttagaa tccgtactag cgagtagaaa cgccaactaa aacacaagac
     7501 gttaaaagac gccagtgagc gtccacgaga ggtgaaaata tgacaaaaag aattctagta
     7561 ttagaagatg gcacagtttt tgaaggcaag gccttcggag cagatattga tgtaacaggc
     7621 gaaatcgtct ttaatacagg gatgaccggc taccaagaat ccattacaga ccagtcttat
     7681 aatggacaaa tcttgacctt tacttatcct ttggtaggaa attatggtat taatcgtgat
     7741 gattatgaat ccattattcc aacttgtaag ggagtcgttg tttttgaaga agcgcgtaga
     7801 gctagcaact ggcgcaacca aatgaccttg gatgaatttt tgaaagccaa gaaaattcca
     7861 gggatttcag gaattgatac gcgtgctctt accaagatta tccgtaagca tggtactatg
     7921 cgtgcaacct tgacccatgt tggggacagt atggaccatg tgacggacca gctccaagca
     7981 acagttttac caacagacaa tatcaaacag gtttctacta aaacgtctta tccagctcca
     8041 ggagttggtt taagcgtggt gctagtggac tttggtctca agcactcaat cctacgtgaa
     8101 ctttctaaac gcaactgtaa cgtgacagtt gttccttatt cgacaacggc tgaagaaatt
     8161 ctccatctca atcctgacgg agttatgttg tcaaatggtc caggtaaccc agaagacgtt
     8221 ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa ttccaatctt tggtatttgt
     8281 atgggacacc aactctttgc aatggcaaac ggggctaaga cctataagat gaagtttggc
     8341 caccgtggat tcaaccatgc ggtacgtgaa atcgcaacag gacgagtaga cttcaccagc
     8401 cagaaccatg gttatgcagt cagccgcgag gatttgccag agcacttgat tattacccac
     8461 gaagaaatca atgacaagtc agtggaaggt gtgcgccaca gataccaacc tgctttctct
     8521 gttcaatacc acccagatgc agctcctggg ccacacgacg ctagctacct atttgacgag
     8581 tttatcgaga tgatggaagt ttttaaacaa tcaaactaag aacgagtaaa agctcgtcgg
     8641 agaatttatg taactgaaca cggacggaaa gctcagaatg tagagaaacc aacttggatt
     8701 gtcaatcctt ccttgatttt ctaaaattca atcgctttct attcgtcctt tgtatcttat
     8761 ttaatgtcgc cctgagaggc gacgaataga aaggagaagg gtgctccgta tttgctgaac
     8821 tgaatacggg ctacggacgg tgctaaaaag atagttattc ctagaactga cagttcttcg
     8881 tcataactcc tattttagct ttgtccgctt gacgccctta atatcttata tatgcctaaa
     8941 cgtactgata ttcaaaaaat tatggtgatt ggttctggtc cgattattat tggtcaggct
     9001 gctgagtttg actacgctgg gactcaggct tgcttgtcgt tgaaagagga aggttatgag
     9061 gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat tgctgacaag
     9121 gtttacattg aaccgattac acttgagttt gtgacacgta ttcttcgtaa ggaacgtcca
     9181 gatgccttgc taccaacact cggtggtcag acaggtctca acatggccat ggaattgtct
     9241 aaaaatggta tcttagatga gcttggcgtt gaacttctgg gtaccaaatt atctgccatt
     9301 gaccaagcgg aggaccgtga cctctttaaa caattgatgg aagagcttga acaacccatt
     9361 ccagaatctg aaattgttaa cacagtagaa gaagcagttg cctttgcagc gacaattggc
     9421 tacccagtca tcgttcgtcc agcctttacc ctcggtggta ctggtggtgg tatgtgtgcc
     9481 aatgagaaag aattgcgtga aatcactgaa aatggtttga aattgtcacc tgttacccaa
     9541 tgtttgattg agcgttcgat tgccggtttc aaggaaattg aatacgaagt gatgcgtgac
     9601 tcagctgaca atgccttggt tgtttgtaac atggaaaact ttgacccagt tgggattcac
     9661 acaggggatt ccattgtatt tgcccctgtg caaaccatgt cagactatga aaaccaaatg
     9721 cttcgtgatg cgagcttgag cattattcgt gccctcaaga ttgaaggtgg atgtaatgtt
     9781 cagctagctc ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa ccctcgtgta
     9841 tcacgttcgt cagcccttgc ttctaaagcg actggatatc cgattgctaa gttggctgcc
     9901 aagattgcag taggtttgac cttggatgag gttataaacc cagttacagg ttcaacctat
     9961 gccatgtttg aaccagccct tgactacgta gttgctaaga ttccacgttt cccatttgac
    10021 aagtttgaaa agggtgaacg ccgtctcggt acacaaatga aggcgactgg agaagtcatg
    10081 gcaatcggtc gtaatatcga ggaatctctt ctcaaggcct gccgctccct tgaaactggg
    10141 gtgcaccaca atgaaatacc tgaacttgca gcagtttctg atgatgcctt gattgaaaag
    10201 gttgtcaaag cccaagatga ccgtctcttc tacgtatcag aagcaattcg tcgtggctac
    10261 acacctgaag aaattgcaga gctaacaaaa attgatatct tctatcttga taaactcttg
    10321 catatctttg aaattgagca agaattgggt gctcatccac aagatctaga agttttgaaa
    10381 acagccaaac ttaatggttt ctcagaccgt aagattgctg aactctgggg aacgactgat
    10441 gatcaagttc gccaacttcg cttggaaaac aagattgttc cagtttataa gatggtagat
    10501 acttgtgcgg cagagttcga ctctgaaacg ccatatttct attcaaccta tggttgggaa
    10561 aatgaatcta tcagatctga taaagaatct gtacttgtcc taggttcagg tccaatccgt
    10621 atcggtcaag gggttgagtt tgactacgca accgttcact ctgttaaggc tatccaggca
    10681 gctggttatg aagctatcat catgaactca aacccagaga ccgtttcaac agacttctct
    10741 gtatcagata agctttactt tgagccattg acattcgaag atgttatgaa cgtcattgac
    10801 ttggaacaac caaagggagt tatcgttcag tttggtggtc aaacagccat caaccttgcg
    10861 gagccattgg caaaagcagg tgtgaccatc cttggtacac aggttgctga cctagaccgt
    10921 gccgaagacc gtgacctctt cgagcaagct ctcaaagaat tggatattcc acagccacca
    10981 ggacaaacgg ctaccaatga agaagaagca gctcttgcag ctcgtaagat tggcttccca
    11041 gttcttgtcc gcccatctta tgtacttggt ggacgtgcca tggaaatcgt tgaaaacgaa
    11101 gaagaccttc gttcttacat gcgaactgct gttaaggcta gtccagatca cccagttctt
    11161 gtcgactctt atatcgttgg gcaagagtgc gaagttgatg ccatttcaga tggtaaagat
    11221 gtactcattc ctggtatcat ggagcatatc gaacgtgctg gtgtccactc aggtgactca
    11281 atggctgttt acccaccaca aaccttgtcg caaaaagttc aggagaccat cgcagactac
    11341 accaaacgct tagcaatcgg tcttcactgc cttggaatga tgaacatcca gtttgttatc
    11401 aaggatgaaa aagtctacgt tattgaggtc aatccacgtg ccagccgtac cgttccattt
    11461 ctatctaagg taaccaatat tcctatggct caagtagcga ccaagctcat tcttggtcaa
    11521 agtttatcag aacttggcta ccaaaatgga ctttaccctg aaagcacccg tgttcatatc
    11581 aaggcacctg tcttctcctt tactaaacta gctaaggtag acagcttgct cggtcctgaa
    11641 atgaagtcaa caggtgaagt tatgggttct gatgctactt tggaaaaagc tctctataaa
    11701 gcctttgaag cttcttatct acacttgcca acttttggta atgtcgtctt taccatcgct
    11761 gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat tggttatgga
    11821 atccttgcga cagaagggac agcagccttc tttgctagtc atggcttgca agcccaacct
    11881 gttggtaaga ttggtgatga cgataaggat atcccaagtt ttgtacgcaa aggaagaatt
    11941 caagctatca ttaacacagt aggaacaaaa cgaactgctg acgaagatgg tgagcaaatt
    12001 cgtcgttcag ccattgaaca cggggtgccc ctcttcacag cgctagatac agctaatgcc
    12061 atgcttaagg tacttgaaag tcgtagcttt gttacagaag cgatttaaat agaaaaataa
    12121 gatatagcag actgaattta gaacagtaca cagggat
//
LOCUS       DAVMBH010000054        11962 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVMBH010000054 DAVMBH010000000
VERSION     DAVMBH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.054"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(115..1746)
                     /locus_tag="VYP30_001775"
     CDS             complement(115..1746)
                     /locus_tag="VYP30_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1808726.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2039..6979
                     /locus_tag="VYP30_001776"
     CDS             2039..6979
                     /locus_tag="VYP30_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1808727.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTSDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKNADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDSLNLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EFNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7069..8265
                     /locus_tag="VYP30_001777"
     CDS             7069..8265
                     /locus_tag="VYP30_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1808728.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8401..8928
                     /locus_tag="VYP30_001778"
     CDS             8401..8928
                     /locus_tag="VYP30_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1808729.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9005..9361
                     /gene="glnR"
                     /locus_tag="VYP30_001779"
     CDS             9005..9361
                     /gene="glnR"
                     /locus_tag="VYP30_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1808730.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9398..10744
                     /gene="glnA"
                     /locus_tag="VYP30_001780"
     CDS             9398..10744
                     /gene="glnA"
                     /locus_tag="VYP30_001780"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1808731.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10840..10959)
                     /locus_tag="VYP30_001781"
     CDS             complement(10840..10959)
                     /locus_tag="VYP30_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1808732.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11447..11962
                     /locus_tag="VYP30_001782"
                     /pseudo
     CDS             11447..11962
                     /locus_tag="VYP30_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3845 a         2184 c         2562 g         3371 t
ORIGIN      
        1 ttctagtttc aatatactat atatctgcag aatactcttt cagtttcatt cagcctagtc
       61 ttgcttagga aaaagtaaga agccatccaa ttatgatgga tagcttcttg gttattagat
      121 ttgttctgca aaaacctttt cagcaaggtt catagcgtgg tctgatacac gagtgtagtg
      181 tgagatgatg tcgataaagt tgaccccagc ttgtgttgaa cattcgcctt tgttgaggcg
      241 tttgatgtgg gtttttctga gaacacgttc tatcttattg attgcttcat gacgttctac
      301 aagactgcgt gctttttcaa tatcattgtt ttccacacta tccagagcat ctttgataaa
      361 gtcactagtt tggcggtaaa cttcctctaa ttctttcaag gcggcatcag aaaattcaac
      421 atttttccgt tgaagatagt cagtcagatt gagtagagcc tccgtgtggt ctccaatccg
      481 ttccaaatca cgggaggaat caaggatatt ggtgagcact tcactttctt tttggctgag
      541 agcttcgctt gaaagggcaa tgagataacg tgttaattgc tcatcgatgg tgttaattgc
      601 ttcttcggtt ttatgccctt tttcagcaac tttttcatcc aagtcaatga tgtacttata
      661 ggaaaggtca aaggctttag cagcgtagtt tcctaagtgc aagagctctt tcttagcatt
      721 tcctagagcg atagatgggg cctgtttgat gaaatgttca tcaagatata agggttcgta
      781 ttttacaacc tcgtcctctc caggaataat cttggttaca aagtaagcca gagctccgat
      841 aaatggaaat tggacaatgg tgttggtaat attaaaggtt ccgtgagcaa aggcgatggt
      901 catttctggt gctagattta gcgtagcttc aaaccaatga atcaggacag taaaaggaac
      961 tagaaaaata acgcagacga ctgttccgat aacgttgaag gcaacatgag ctcctgctac
     1021 ccgtttagct gcaatattag cccctaaaga ggcaatgatg gctgtaatgg ttgtcccgat
     1081 attgtcacca aatagaactg gcaaagctcc ctgtaggtca attagattgc cggcgtagag
     1141 gttttgtaaa atcccaatgg tagccgaaga agcttgaatt agcaaggtca agccggtacc
     1201 gacaaagaca cccaaaacag gattcttact tagctcaatc atatagtcct taaagacctg
     1261 taaatccttg agtggagcca ttgcgccgct catgagattg agggcaaaaa agataccacc
     1321 gacaccaaag aggatgcgtc cgatattatt gactgtccga ttttttgtaa aaaagagaca
     1381 gacggcaccg ataaagagca taggtagggc atagttacct aatttaaaac cgatgagaaa
     1441 ggatgtgaca gttgtcccaa tattagcacc catgacaatc ccgatagcct gacgtaaggt
     1501 taagagaccg gcactgacca ggccgactgt aataactgtt acaccagaac tagactgaat
     1561 tagagcagtc atcccaatac caaccagaac tccaaagaaa ggattactag tatatttgtc
     1621 aatgtaaaaa cgaaggcgat ctccagcagc ttgttgcaaa ccgtctccca tggtcttgat
     1681 actatataag aatagcccca gaccacctaa aaagtgaaat aaaatttcct gccaattaat
     1741 ggacatttct ttttcctccg aaaaataatc gcggaatatc tcctattcta ttttaaagga
     1801 taaaagtaaa tctaacaagt gttaatgtca agtttgtaaa agaaaattat aattgataag
     1861 tgtattattt ttaagagttt ttaaccttat tttagatttg tgaaaacagc tattgttttt
     1921 tgtctaaaaa tgttttagga taaaaatgtg attatcatgg ttctagagtt tgataaaaaa
     1981 ctacagaata taaagcgctt tcttgaaaac aacaaaatca atcttttagg aggagaaaat
     2041 gaagaatcca ttttttgaaa gacgttgtcg ttacagtatt cgtaagttat cagtaggagc
     2101 ctgctcgctg atgattggtg ctgttttatt tgttggtcca gccttggctg aagaaactgc
     2161 agttcctgaa aatagcggag ctaatacaga gcttgtttca ggagagagtg agcattcgac
     2221 caatgaagct gataagcaga atgaagggga acatactaga gaaaacaagc tagaaaaggc
     2281 agaaggagta gcgacagcat ctgaaactgc agaagcagct agcgcagcta aaccagagga
     2341 aaaagcaagt gaggtggttg cagaaacacc atctgcagaa gcaaaaccta agtctgacaa
     2401 ggaaacagaa gcaaagcccg aagcaactaa ccaaggggat gagtctaagc cagcagccga
     2461 agctaataag actgaaaaag aagtccagcc agatgtccct aaaaatacag aaaaaacatt
     2521 aaaaccaaag gaaatcaaat ttaattcttg ggaagaattg ttaaaatggg aaccaggtgc
     2581 tcgtgaagat gatgctatta accgcggatc tgttgtcctc gcttcacgtc ggacaggtca
     2641 tttagtcaat gaaaaagcta gcaaggaagc aaaagttcaa gccttatcaa acaccaattc
     2701 taaagcaaaa gaccatgctt ctgttggtgg agaagagttc aaggcctatg cttttgacta
     2761 ttggcaatat ctagattcaa tggtcttctg ggaaggtctc gtaccaactc ctgacgttat
     2821 tgatgcaggt caccgtaacg gggttcctgt atacggtaca ctcttcttca actggtctaa
     2881 tagtattgca gatcaagaaa gatttgctga agctttgaag caagacgcag atggtagctt
     2941 cccaattgcc cgtaaattgg tagacatggc caagtattat ggctatgatg gctatttcat
     3001 caaccaagaa acaactggag atttggttaa acctcttgga gaaaagatgc gccagtttat
     3061 gctctatagc aaggaatatg ctgctaaggt aaaccatcca atcaagtatt cttggtacga
     3121 tgccatgacc tataactatg gacgttacca tcaagatggt ttgggagaat acaactacca
     3181 attcatgcaa ccagaaggag ataaggttcc ggcagataac ttctttgcta actttaactg
     3241 ggataaggct aaaaatgatt acactattgc aactgccaac tggattggtc gtaatcctta
     3301 tgatgtattt gcaggtttgg aattgcaaca gggtggttcc tacaagacaa aggttaagtg
     3361 gaatgacatt ttagacgaaa atgggaaatt gcgcctttct cttggtttat ttgccccaga
     3421 taccattaca agtttaggaa aaactggtga agattatcat aaaaatgaag atatcttctt
     3481 tacaggttat caaggagacc ccactggcca aaaaccaggt gacaaagatt ggtatggtat
     3541 tgctaaccta gttgcggacc gtacgccagc ggtaggtaat acttttacta cttcttttaa
     3601 tacaggtcat ggtaaaaaat ggttcgtaga tggtaaggtt tctaaggatt ctgagtggaa
     3661 ttatcgttca gtatcaggtg ttcttccaac atggcgctgg tggcagactt caacagggga
     3721 aaaacttcgt gcagaatatg attttacaga tgcctataat ggcggaaatt cccttaaatt
     3781 ctctggtgat gtagccggta agacagatca ggatgtgaga ctttattcta ctaagttaga
     3841 agtaactgag aagaccaaac ttcgtgttgc ccacaaggga ggaaaaggtt ctaaagttta
     3901 tatggcattc tctacaactt cagactacaa attcgatgat gcagatgcat ggaaagagct
     3961 aaccctttct gacaactgga caaatgaaga atttgatctc agctcactag caggtaaaac
     4021 catctatgca gtcaaactat ttttcgagca tgaaggtgct gtaaaagatt atcagttcaa
     4081 cctaggacaa ttaactatct cggacaatca ccaagagcca caatcgccga caagcttttc
     4141 tgtagtgaaa caatctctta aaaatgccca agaagcggaa gcagttgtgc aatttaaagg
     4201 caacaaggat gcagatttct atgaagttta tgaaaaagat ggagacagct ggaaattact
     4261 aactggctca tcttctacaa ctatttatct accaaaagtt agccgctcag caagtgctca
     4321 gggtacaact caagaactga aggttgtagc agtcggtaaa aatggagttc gttcagaagc
     4381 tgcaaccaca acctttgatt ggggtatgac tgtaaaagat accagcctac caaaaccact
     4441 agctgaaaat atcgttccag gtgcaacagt tattgatagt actttcccta agactgaagg
     4501 tggagaaggt attgaaggta tgttgaacgg taccattact agcttgtcag ataaatggtc
     4561 ttcagctcag ttgagtggta gtgtggatat tcgtttgacc aagccacgta ccgttgttag
     4621 atgggtcatg gatcatgcag gggctggtgg tgagtctgtt aacgatggct tgatgaacac
     4681 caaagacttt gacctttatt ataaaaatgc agatggtgag tggaagctag ctaaggaagt
     4741 ccgtggcaac aaagcacacg tgacagatat cactcttgat aaaccaatca ctgctcaaga
     4801 ctggcgcttg aatgttgtca cttctgacaa tggaactcca tggaaggcta ttcgtatcta
     4861 taactggaaa atgtatgaaa agcttgatac tgagagtgtc aatattccga tggccaaggc
     4921 tgcagcccgt tctctaggca ataacaaggt acaagttggc tttgcagatg tacaggctgg
     4981 agcaactatt accgtttatg ataatccaaa ttctcaaact ccgctcgcaa ccttgaagag
     5041 cgaagttgga ggagacctag caagtgcacc attggatttg acaaatcaat ctggtcttct
     5101 ttattatcgt acccagttgc caggcaagga aattagtaat gtcctagcag tttccgttcc
     5161 aaaagatgac agaagaatca agtcagtcag cctagaaaca ggacctaaga aaacaagcta
     5221 cgccgaaggg gaggatttgg accttagagg tggtgttctt cgagttcagt atgaaggagg
     5281 aactgaggac gaactcattc gcctaactca cgcaggtgta tcagtatcag gttttgatac
     5341 gcatcataag ggagaacaga atcttactct ccaatatttg ggacaaccgg taaatgctaa
     5401 tttgtcagtg actgtcactg gccaagacga agcaagtccg aaaactattt tgggaattga
     5461 agtaagtcag gaaccgaaaa aagattacct agttggtgat agcttaaact tgtctgaagg
     5521 acgctttgca gtggcttata gcaatgacac catggaagaa cattccttta ctgatgaggg
     5581 agttgaaatt tctggttacg atgctcaaaa gactggtcgt caaaccttga cgcttcgtta
     5641 ccaaggtcat gaattcaatt ttgatgtttt ggtatctcca aaagcagcat tgaacgatga
     5701 gtacctcaaa caaaaattag cagaagttga agctgctaag aacaaggtgg tctataactt
     5761 tgcttcacca gaagtaaaag aagctttctt gaaagcaatt gaagcggccg aacaagtgtt
     5821 gaaagaccat gaaactagca cccaagatca agtcaatgac cgacttaata aattgacaga
     5881 agctcataaa gctctgaatg gtcaagagaa atttaaggaa gaaaagacag aacttgatcg
     5941 cttaacaggt gaggttcaag aactcttggc tgccaaacca aaccatcctt caggttctgc
     6001 cctagctccg cttcttgaga aaaacaaggc cttggttgaa aaagtagatt tgagtccaga
     6061 agagcttgca acagcgaaac agagtctaaa agatctggtt gctttattga aagaagacaa
     6121 gccagcagtc ttttctgata gtaaaacagg tgttgaagta cacttctcaa ataaagagaa
     6181 gactgtcatc aagggtttga aagtagagcg tgttcaagca agtgctgaag agaagaaata
     6241 ctttgctgga gaagatgctc atgtctttga aatagaaggt ttggatgaaa aaggtcaaga
     6301 tgttgatctc tcttacgctt ctattgtgaa aatcccaatt gaaaaagata agaaagttaa
     6361 gaaagtattt ttcttacctg aaggcaaaga ggcagtagaa ttgacttttg aacaaacgga
     6421 tagtcatgtt atctttacag caccacactt tactcattat gcctttgttt atgaatctgc
     6481 tgaaaaacca caacctgcta aaccagcacc acaaaacaaa gtccttccaa aacctactta
     6541 tcaaccggct tctgatcaac aaaaggctcc taaattggaa gttcaagagg aaaaggttgc
     6601 ctttcatcgt caagagcatg aaaatgctga gatgctagtt ggggaacaac gagtcatcat
     6661 acagggacga gatggactgt taagacatgt ctttgaagtt gatgaaaacg gtcagcgtcg
     6721 tcttcgttca acagaagtca tccaagaagc gattccagaa attgttgaaa ttggaacaaa
     6781 agtaaaaaca gtaccagcag tagtagctac acaggaaaaa ccagctcaaa atacagcagt
     6841 taaatcagaa gaagcaagca aacaattgcc aaatacagga acagctgatg ctaatgaagc
     6901 cctaatagca ggcttagcca gcctcggtct tgctagttta gccttgacct tgagacggaa
     6961 aagagaagat aaagattaaa tatcgaaaaa tcttgtgaaa tctttcctta tatttccaaa
     7021 gtgtgatata atagtttcga ataaaataaa taaaggagtt tttgtaacat ggcaaaactt
     7081 actgttaaag acgttgactt gaaaggtaaa aaagtcctcg ttcgtgttga cttcaacgta
     7141 ccattgaaag atggcgtaat cactaacgat aaccgtatca cagcagctct tccaactatt
     7201 aagtacatca tcgaacaagg tggacgtgca attcttttct ctcaccttgg acgtgtgaaa
     7261 gaagaagctg ataaagctgg taaatcactt gctcctgtag cagctgactt ggcagcaaaa
     7321 cttggtcaag atgttgtttt cccaggtgtc actcgtggtg ctgaattgga agcggcaatc
     7381 aacgctcttg aagatggaca agttctcttg gttgaaaaca ctcgttacga agatgttgac
     7441 ggcaagaaag aatctaaaaa cgatcctgaa cttggtaaat actgggcatc acttggagat
     7501 ggtatcttcg taaacgatgc attcggtaca gctcaccgtg cacacgcatc taacgttggt
     7561 atctcagcaa acgttgaaaa agcagttgct ggtttccttc ttgaaaacga aattgcctac
     7621 atccaagaag cagttgaaac tccagaacgt ccattcgtgg ctatccttgg tggttcaaaa
     7681 gtttcagaca agatcggtgt tatcgaaaac ttgcttgaaa aagctgataa agtccttatc
     7741 ggtggtggga tgacttacac attctacaaa gcacaaggta tcgaaatcgg taactcactt
     7801 gtagaagaag acaaattgga tgttgcgaaa gctcttcttg aaaaagcaaa tggtaaattg
     7861 atcttgccag ttgactcaaa agaagctaac gcatttgctg gttacactga agtgcgtgac
     7921 actgaaggtg aagcagtttc tgaaggcttc cttggtcttg acatcggtcc aaaatctatc
     7981 gccaaatttg acgaagcttt gactggtgcc aaaacagttg tatggaacgg acctatgggt
     8041 gtatttgaaa acccagattt ccaagctggt acaatcggtg tgatggacgc tatcgtgaaa
     8101 caaccaggag ttaaatcaat catcggtggt ggtgactcag ctgccgcagc gattaacctt
     8161 ggccgtgcag acaagttctc atggattagt acgggtggtg gagcatcaat ggaacttctt
     8221 gaaggtaagg ttcttccagg acttgcagcc ctgacagaaa aataagattt tataaacaaa
     8281 tcaaagaaga gagggatgaa agttcctctt ttcttttgct taaaataaaa acgcttcctc
     8341 tcaactatta ctcataaaaa tcaccgattt atgataaaat ggaaatagaa agttgagatt
     8401 atgagttatt ttaaaaaata taaattcgat aaatcccagt tcaaacttgg tatgcgaacc
     8461 tttaaaacag gtattgctgt ttttctagtt ctcttgattt ttggcttttt tggctggaaa
     8521 ggtcttcaaa ttggtgcttt gacagccgtt tttagcctga gggagagttt tgatgagagt
     8581 gttcattttg ggacttcgcg tattctagga aatagtatcg gtggactcta tgccttggtc
     8641 tttttcttat taaatacctt tttccacgaa gccttttggg tgaccttggt agttgttcca
     8701 atctgcacca tgttaaccat tatgacaaat gtagccatga ataacaaagc aggggttatt
     8761 ggtggtgtag cagctatgtt aatcattacc ctatcaattc caagtggtga gacaattttg
     8821 tacgtgtttg tgcgtgtatt agaaacgttt atgggagttt ttgtcgcaat tatcgtaaat
     8881 tacgatattg atcgtattcg tctcttttta gagaaaaaag aaaaataatg ttacatttta
     8941 taacattatc aattgacgtt tgtctttttt tagactataa tagacagaaa gaaggaaatt
     9001 gtaaatgaag gaaaaagaat ttcgccgaaa tatggctgtt tttcctatcg gcagtgttat
     9061 gaagttgacc gatttatcgg cgcgtcagat tcgttattat gaagatcaag agttgatcaa
     9121 gcccgatcga aacgaaggaa atcgtcgcat gtattccttg aatgacatgg atcgtctgct
     9181 tgaaatcaaa gattatatct ctgaaggtta taatatcgct gccattaaga aaaaatatgc
     9241 tgaacgtgaa gcgaaatcca agaaagcggt tagtcagact gaagtacgtc gtgcacttca
     9301 caatgaactc ctccaacagg ggcgttttgc ttcagtacag tcaccttttg gtcgcggtta
     9361 ggcaaccgca agtagtcata gattaaggag aaaacttatg ccaatcacag ctgcagatat
     9421 tcgtcgtgaa gtcaaggaaa aaaatgttac ctttattcgt cttatgttct cagatatttt
     9481 gggaaccatg aaaaacgtcg aaattcctgc tacagatgaa cagttagata aggtcttgtc
     9541 gaacaaggtt atgtttgatg gatcttctat tgaaggtttt gtacgtatca atgagtcgga
     9601 tatgtacttg tacccggact tggatacatg gacagtcttc ccttggggag atgaaaatgg
     9661 aagtgttgca ggtctgatct gtgatgtcta tacaacagaa ggtgaaccat ttgcgggtga
     9721 ccctcgtggt aatttgaaac gagctcttcg tcacatggaa gaagttggat tcaaatcctt
     9781 caaccttggt ccagagccag aattcttcct atttaagttg gatgaaaatg gggacccaac
     9841 acttgaagtg aatgacaagg gtggctactt tgacttggca cctactgatc ttgcggacaa
     9901 cacacgtcgt gagattgtga atgtcttgac caaaatggga tttgaagtag aagcgagtca
     9961 ccacgaggtt gcggttggac agcatgagat tgactttaag tacgatgaag ttctccgtgc
    10021 ttgtgataag attcaaatct ttaagcttgt tgttaaaacc attgctcgca aacacggact
    10081 ttacgcaaca tttatggcga agccaaaatt tggtattgct ggatcaggta tgcactgtaa
    10141 tatgtccttg tttgatgcag aaggaaataa cgccttcttt gatccaaatg atccaaaagg
    10201 aatgcagttg tcagaaacag cttaccattt cctaggcggt ttgatcaagc atgcttacaa
    10261 ctatactgct atcatgaacc caacagttaa ctcatacaaa cgtttggttc caggttatga
    10321 agcgcctgtt tacattgctt gggctggtcg taaccgttcg ccacttgtgc gcgtacctgc
    10381 ttcacgtggt atgggaactc gtcttgagtt gcgttcagtg gatccaatgg cgaaccctta
    10441 cgttgctatg gctgttcttt tggaagttgg tttgtatggt attgaaaata aaatcgaagc
    10501 accagctcct atcgaagaaa atatctacat catgacagca gaagagcgca aggaagctgg
    10561 tattacagac cttccatcaa ctcttcacaa cgctttgaaa gctttgacag aagatgaagt
    10621 ggttaaagct gctctcggag atcacatcta tactagcttc cttgaagcca aacgaatcga
    10681 atgggcaagt tatgcaacct tcgtttcaca atgggaaatt gataattatt tagaccttta
    10741 ctaatactaa tatagaagaa agattgcctg tgggtaaaca gtcacacagc agtctaagcc
    10801 atcaaatacc tataaccctt aaaatagcga tttcggtcgc tatttatttt tcgaaaaatc
    10861 ctcttgactc ttttgcgaat tagatttatc atcagacgtg tagaagaaaa ttaaggagtc
    10921 actatggaaa aattcaattt caaaaacaat atcgggcaag aaaacaagtt acttcaaatc
    10981 gaaatctaca agtttactaa cttttgcaag cttcaaaatt acacatctgt aaatattttt
    11041 tcgaaagata tatttgaagc catagtaaat tgagactaga atagtacact acatctgcta
    11101 aaaatttcta gaaactaatt taactttcct aatcgatttg tttacatctt atttcaatct
    11161 actatattat ctcaataaat gatgatggcg actgttttgt ttgtgcttgt cgatttttga
    11221 atcctgatcg agcggaagaa tatttctgcc gaggttgcca aggggaaaat cctgaagata
    11281 ttgaatttta tgatgaacaa ttacaggcag aaaaggtgga ggttttgaat attcgattgg
    11341 aagtaaaaaa ttgaattatc tacaatctca tcaacaataa acctatttca accccattat
    11401 ctataggcgt atttttacgc ctttttatat acttgaagca cataagaaac attatgggaa
    11461 gtttgctgat ggaagcactc aagaaattga tgttccttat gatattcctg atacttggga
    11521 gtgggtgagg ataaaatcaa tttattggaa ttttgggcaa aataagccag agaaatcctt
    11581 taggtatata gatacgtcta gtattgatag aaaaaagaat ataatcaact acaaaaatct
    11641 acaatatctt tcacctgaac aagcgccttc ccgtgctaga aaattagttt cgcagaatag
    11701 tgtcttattt tcaacagtta gaccatatct aaaaaatatt gctgtagtta gagaacttaa
    11761 agagtatttg atagctagta cagcatttat tgttttggat actttactta acgaaacata
    11821 tttgaaatat tatttattat cagataattt tatcaatcgt gttaataata aatctactgg
    11881 aacaagttat cctgcaatca atgattataa ttttaatcta ttattaattg ctctcccccc
    11941 actatccgaa caacaacgaa ta
//
LOCUS       DAVMBH010000055        11957 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVMBH010000055 DAVMBH010000000
VERSION     DAVMBH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.055"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            74..352
                     /locus_tag="VYP30_001783"
     CDS             74..352
                     /locus_tag="VYP30_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808733.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            354..2417
                     /locus_tag="VYP30_001784"
                     /pseudo
     CDS             354..2417
                     /locus_tag="VYP30_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
     gene            complement(2495..3751)
                     /locus_tag="VYP30_001785"
     CDS             complement(2495..3751)
                     /locus_tag="VYP30_001785"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1808734.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            3893..6358
                     /locus_tag="VYP30_001786"
     CDS             3893..6358
                     /locus_tag="VYP30_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1808735.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVDDYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            6423..7334
                     /locus_tag="VYP30_001787"
     CDS             6423..7334
                     /locus_tag="VYP30_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1808736.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            7564..8262
                     /gene="dapD"
                     /locus_tag="VYP30_001788"
     CDS             7564..8262
                     /gene="dapD"
                     /locus_tag="VYP30_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1808737.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            8330..9460
                     /locus_tag="VYP30_001789"
     CDS             8330..9460
                     /locus_tag="VYP30_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1808738.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            9472..10014
                     /locus_tag="VYP30_001790"
     CDS             9472..10014
                     /locus_tag="VYP30_001790"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1808739.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQFIDQTLTERLLHHPFYQEAKVI
                     ATYLSFPHEFQTQELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPEFDKDIPVQEVLIDEGNL"
     gene            9998..10675
                     /locus_tag="VYP30_001791"
     CDS             9998..10675
                     /locus_tag="VYP30_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1808740.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            10689..10766
                     /locus_tag="VYP30_001792"
                     /pseudo
     CDS             10689..10766
                     /locus_tag="VYP30_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10976..11911)
                     /locus_tag="VYP30_001793"
     CDS             complement(10976..11911)
                     /locus_tag="VYP30_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808741.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGGQDYSGSGDSSTNGGSSEQYSSRNSNSGANNGYYKKYKNIDASG
                     HVRDTYHNESNGDVFDENGNYLGNTGGGIAEPPQR"
BASE COUNT         3377 a         2192 c         2664 g         3724 t
ORIGIN      
        1 attctccaat ttatagaatg aaattgcttt tatatctaaa ttgctatata ataatgataa
       61 ggaggaaata agtatgttaa aagaagtatt aaccgttgca aaagttgcga aaaaatcttc
      121 attatttttg ggtggtgtcg catttggtac ccttggtttg aaaatcttag caagtaagga
      181 agctaaaaaa ggttattcta aagctttggc taaggcttac aagttgaaag acgagctaga
      241 tgcatctgtt tctgttgtga agcaacatgg agacgatgtc ttgcaagatg ccaaatattt
      301 gtacgagcaa gagaaaaaag aagagcaatt agatagcctt ataggtgaat aatatgtctt
      361 ttaaagtgct acatagagga taccaacata tccgactatc atcttctttt tcacttacct
      421 tggatattca agactatctt cgttccttgg cgagagatga aaaggggatt gagtctatcc
      481 agttttacat ggatcaacag cactttactc tacgcataaa agaaggcttt tctgtattag
      541 ataatgcaga agccttttta aaaagaattg ataaagggaa agtttctgag ttgatgactc
      601 ttcccattcg tagagaagag agtgcttatt ctattgtttc aggtgcagcg gttaagcgtg
      661 tactttttcg tagttttgtg ccgtatccta ttcgctatat atggacttgt tatcaggctt
      721 tgggttatat tagagaagcc tatcaaacac tagcgcgtaa ggaactaacg atggaagtct
      781 tggactgttc ggctatttta ttgtctttgt ttatgaacca atccaagaca gctagcaata
      841 tcatgtttat gcttgatttg gggaatcatt tagatcagtg gtccttgaaa aaaactgcaa
      901 cagatttaga acagagtctt cttgcaaaag agagcgatgt attcctagta cagggcgata
      961 cggttgttag tatcaagagt tccgatgttc aaataggaga tgtcttgatc ttatctcaag
     1021 gaaatgaaat tctgtttgat ggacaagtag tttcaggttt aggtatggtc aacgaaagtt
     1081 ccttgacagg agagagtttt ccagttgaaa aaagagagtc tgatttggtt tgtgcaaata
     1141 cagtattaga aactggagag ttacgcattc gtgtaacaga taatcagatg aacagccgta
     1201 ttttacagct gattgagttg atgaagaaat ctgaagaaaa caagaaaacg aaacaacgct
     1261 atttcatcaa gatggcggat aaagtcgtca aatataattt cttgggggct gggctgactt
     1321 acctattgac aggttctttt tctaaggcta tttctttcct attggtcgat ttctcctgcg
     1381 ctttgaaaat ctctactcct gtagcttatt tgacagttat caaggagggg ttgaaccgtg
     1441 aaatggtgat taaggatgga gatgttctgg agaaatatct ggaagttgat actttcttgt
     1501 ttgataagac aggaacaatc acaactagtt atcctatagt tgaaaaggtg ttaccttttg
     1561 gagactatag tgaggaagat attctcagaa tcagtgcctg tcttgaggaa cacatttatc
     1621 atcctattgc taatgccatc gtcaagcaag ctgagataga gggaattgaa catgaggaaa
     1681 tgcatgggaa actccaatat atcgcaagca aggggatcaa atctcatata gatggccaac
     1741 cagttcttat tgggaattat gtcttgatgc aggatgagta gattcatatc agttcagaac
     1801 aaaatgcttt aattgaagag tacaagagtc actacaatct cttattcttg gcttatcaaa
     1861 atgaattgat tggaatgttc tgcattcata ctcctttgag aaaagaagca aaaacagcct
     1921 tggataaact taaggcacag gggaaaaaat tgattctggc aacaggagac accttgatta
     1981 ggacagagga attagtcaaa gatttgccct ttgatcaggt ctatacagac ttgaaacctg
     2041 atgggaaatt tgagttagta gagaaactgc agaaagcagg tcacactatt ttgatggttg
     2101 gagatggatt gaatgactca gcggctttaa ctctatcaga tatcggtgtg gtgatgaatg
     2161 agagtgcaga tatttctaag cagatgagtg atatcttatt gttagataat cgtttggatt
     2221 tcttccaaga gttggattcg ttatcatcat ctttgcaaac actcatcaag aaaaatattc
     2281 aagataccgt tgtcgtaaat agtagtttga ttggctttgg cttatttaat tggttcagtc
     2341 cttcaaatct ctctatctta cataatctaa caaccttgcg cattgtcttg cgtagcctgt
     2401 ctattaaaaa tagatagatg agagttatta acagcaaaaa ggagttacct ttctcgaggt
     2461 taactccttt gtttatagat aaatgttgaa tagtttagta agtcaataca aagtattttt
     2521 tcttcccacg acggataaca gtcagttcat tttctaactt atcagcgtca ctcaagacat
     2581 agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc tccgttttgg acgtcttcac
     2641 gggcttggcg ttttgagtta actataccag atgagacgag cagttccacg atattgttat
     2701 gttcgtctgc ctgtacttgg tagtttggca caccacgaag tccttgtttg agctctttga
     2761 cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt gatgttaagt gcttctttgt
     2821 aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc caagactttt tgagccaagc
     2881 gttcgtgtgg cgctgcttca aattgtttac gaatatcttc aatctcatca agtgacaaga
     2941 aagtaaagat tttcaagaag cgaacagcgt cagcgtccat cacgttcatc cagaattggt
     3001 acatttcgta tggagaagtc ttttcgggat tgagccagac ggcatttcct tctgatttac
     3061 caaatttttt accagttgca tctgtgatta gtggaacagt gataacgtga ccagtcttgt
     3121 ccgccttacg acgaagcaat tcggtaccag ctgtcatatt tccccactgg tcagaaccac
     3181 cgatttgaag agtgacatta tggtcttggt taaggacgaa gaagtcgtac ccttgcatga
     3241 tttggtaagc gaactcagtg taagaaattc ctgtttcgat ccgtttttta acagattcct
     3301 tactcatcat gtagttgacc gtgaagtatt ttccaatatc acggaggaag tcaatgaagc
     3361 tgatgctgcc aaaccagtcg tagttgttga ccatgacagc cttgttttcg ccattttcaa
     3421 agtcaagaaa acgagaaagt tgtccttgga tagacttgac ccagccatct actgtgtctt
     3481 ttgtttggag actacgttca gcatctttga aggacggatc tccgatgaga cctgtagcac
     3541 cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa gcgacgactt gtcaagattg
     3601 cgacaaggtg gcctaggtga aggctgtcag cagttggatc gtagccagta taataagaaa
     3661 cttgaccttc ttctagggct ttacgcaaag cttcttcatc agtcgtttga aatatcaaac
     3721 cacgctcttt tagctcatca aaaatgtgca tgtgtctttt ctccttttta aaattattgt
     3781 ttctacctat tgtatcacaa acttgggcaa tagcctagca gaatagggaa gaaagtggct
     3841 attttattga aaatttccct tttgtggtat aatagataga gtgaggaaat ccatgcaaaa
     3901 tcaattaaat gaattaaaac gaaaaatgct ggaatttttc cagcaaaaac aaaaaaataa
     3961 aaaatcagct agacctggca agaaaggttc aagtaccaaa aaatctaaaa ccttagataa
     4021 gtcagccatt ttcccagcta ttttactgag tataaaagcc ttatttaact tactctttgt
     4081 actcggtttt ctaggaggaa tgttgggagc tgggattgct ttggggtacg gagtggcctt
     4141 atttgacaag gttcgggtgc ctcagacaga agaattggtg aatcaggtca aggacatctc
     4201 ttctatttca gagattacct attcggacgg gacggtgatt gcttccatag agagtgattt
     4261 gttgcgcact tctatctcat ctgagcaaat ttcggaaaat ctgaagaagg ctatcattgc
     4321 gacagaagat gaacacttta aagaacataa gggtgtagta cccaaggcgg tgattcgtgc
     4381 gaccttgggg aaatttgtag gtttgggttc ctctagtggg ggttcaacct tgacccagca
     4441 actaattaaa cagcaggtgg ttggggatgc gccgaccttg gctcgtaagg cggcagagat
     4501 tgtggatgct cttgccttgg aacgcgccat gactaaagat gagattttaa cgacctatct
     4561 caatgtggct ccctttggcc gaaataataa gggacagaat attgcagggg ctcggcaagc
     4621 agctgaggga attttcggtg tagatgccag tcagttgact gttcctcaag cagcattttt
     4681 agcaggactt ccacagagtc ccattactta ctctccttat gaaaatactg gggagttgaa
     4741 gagtgatgaa gacctagaaa ttggcttaag acgggctaag gcagttcttt acagtatgta
     4801 tcgtacaggt gcattaagca aagacgagta ttctcagtac aaggattatg accttaaaca
     4861 ggacttttta ccatcgggca cggttacagg aatttcacga gactatttat actttacaac
     4921 tttggcagaa gctcaagaac gtatgtatga ctatctagct cagagagaca atgtctccgc
     4981 taaggagttg aaaaatgagg caactcagaa gttttatcga gatttggcag ccaaggaaat
     5041 tgaaaatggt ggttataaga ttactactac catagatcag aaaattcatt ctgccatgca
     5101 aagtgcggtt gatgattatg gctatctttt agacgatgga acaggtcgtg tagaagtagg
     5161 gaatgtcttg atggacaacc aaacaggtgc tattctaggc tttgtaggtg gtcgtaatta
     5221 tcaagaaaat caaaataatc atgcctttga taccaaacgt tcgccagctt ctactaccaa
     5281 gcccttgctg gcctacggta ttgctattga ccagggcttg atgggaagtg aaacgattct
     5341 atctaactat ccaacaaact ttgctaatgg caatccgatt atgtatgcta atagcaaggg
     5401 aacaggaatg atgaccttgg gagaagctct gaactattca tggaatatcc ctgcttactg
     5461 gacttatcgt atgctccgtg aaaagggtgt tgatgtcaag ggttatatgg aaaagatggg
     5521 ttacgagatt cctgagtacg gtattgagag cttgccaatg ggtggtggta ttgaagtcac
     5581 agttgcccag cataccaatg gctatcagac cttagctaat aatggagttt atcatcagaa
     5641 gcatgtgatt tcaaagattg aagcagcaga tggtagagtg gtgtatgagt atcaggataa
     5701 accggttcaa gtctattcaa aagctactgc gacgattatg cagggattgc tacgagaagt
     5761 tctatcctct cgtgtgacaa caaccttcaa gtctaacctg acttctttaa atcctactct
     5821 ggctaatgca gattggattg ggaagactgg tacaaccaac caagacgaaa atatgtggct
     5881 catgctttcg acacctagat taaccctagg tggctggatt gggcatgatg ataatcattc
     5941 attgtcacgt agagcaggtt attctaataa ctctaattac atggctcatc tggtaaatgc
     6001 gattcagcaa gcttccccaa gcatttgggg gaacgagcgc tttgctttag atcctagtgt
     6061 agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca gggaaggttt ctgttgaagg
     6121 aaaagaagta gaggtcacag gttcgactgt taccagctat tgggctaata agtcaggagc
     6181 gccagcgaca agttatcgct ttgctattgg cggaagtgat gcggattatc agaatgcttg
     6241 gtctagtatt gtggggagtc taccaactcc atccagctcc agcagttcaa gtagtagttc
     6301 tagcgatagc agtaactcaa gtactacacg accttcttct tcaagggcga gacgataatt
     6361 ctctaaatga agtggccaat caatggattg ccactttttt cctttcgtgt tacaataagg
     6421 gtatgaatca gtatcagaaa aagattgtta acggaaaaat ttattcgctc ctatccggct
     6481 taatatgggg aatctgtgga attttaggag agtacttctt tactcattat caggtgtctt
     6541 cgggctggat tacctctatg cgtttgacac tggcagggag tcttgtactc atttggtctg
     6601 caatacaatt aaaatcgcaa gtgctagata tttggcgaga caagaaaaat tacctgccct
     6661 ttttagccta tgctattttg gggatttttt cagttcagta ttttttctat ctctgtgtag
     6721 aatactcaaa tgctacgaca gcaactattt tacagtttat tagccctgtc tttatcctct
     6781 tttacaatcg cttggtttat caaaaacgag cgtcaaaaag cgctgttttc tatgttttgg
     6841 ttgccatgct gggtgtttgc ttgatggcga caaagggaga tctctctcag ttatccatga
     6901 cgccgctagc tcttataaca ggtttgctga gtgccatggg tgttatgttt aatgttatct
     6961 tgccccaacc ttttgctaag cgttatggtt ttgttcctac ggttgggtgg gggatgattt
     7021 tggcaggttt gtttagcaat gtcctctcgc cggtttatca gctttccttt actcttgata
     7081 tttggagtat cttgatttgc ctcattatcg ctttctttgg aacggctttt gcttttttca
     7141 tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt tgccgttatc agtgccagtg
     7201 aacctctctc ttctgctctc ttgagtgttt tgttcttagg attagtagtg gattggtccc
     7261 tccttctagc tatagccttg attattttac ccatgatatt tttgtctata gaagaagcga
     7321 aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg tgctatacta gaatagtcaa
     7381 taaaacacgg ggagatagtt gtgaagagtg tttttaggtt gtatcggtag gggcttgctt
     7441 ttaccgacag cacgttttat ctcacatccc taaaaaatca tacctaaaaa cagacaaaaa
     7501 ggtttcaaat ttgaggcctt ttttggtaga ataggtatca ttataacgaa ccaggaggca
     7561 cctatgactg ctacaaaaat gaacgctcaa gaaattatcc aatttatcgc caatgctgaa
     7621 aagaaaacca gtgtcaaagt aacctttgag gggcaactcg caactgctgt gcctagctct
     7681 gttgtcaaac taggaaatgt cctattcgga gactggaagg acgtggctcc gcttcttgaa
     7741 ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg ctcgtaattc tgcagttcct
     7801 ttgctagata agcgtgctat caacgctcgt atcgagccag gtgctattat ccgtgaccag
     7861 gtggaaattg gtgacaatgc tgttatcatg atgggagctg ttatcaatat cggtgctgaa
     7921 atcggtgctg gaaccatgat tgacatgggt gccatccttg gtggccgtgc catcgttgga
     7981 aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg tgattgagcc agctagtgct
     8041 gaaccagtcc gtgtcggaga caatgttctt atcggtgcta atgcagtggt tatcgaagga
     8101 gtccaaatcg gtagtggttc agttgtcgca gcaggagcta ttgttaccca agatgtccca
     8161 gaaaacgtgg tagtagcagg tgttccagct cgtattatca aagaaattga tgcccaaact
     8221 caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt aattgtaaaa gtaaaaaaga
     8281 ggcggaaccc tttttccagc ctctttctgc tatatcggag gacagataga tgttagattt
     8341 gattcagact agacgagctt tacaccagat tccagagatt ggcttggagg agttcaagac
     8401 tcaggcttat ttgctggatg tgattgagaa attgactacg ggcaaggatt ttgttcaaat
     8461 tcgtacttgg cggacaggga ttttggtcta cctgcaggga agtcagccgg agcgaaccat
     8521 tggttggcgg acagatattg atggcctgcc tatcgtcgaa caaacaggtc taccttttgc
     8581 ttctcaacac caaggtcgca tgcatgcctg tggccatgat tttcatatga ccattgcctt
     8641 aggctgtctt gagcgcgccc ttgaggagca acccaagaat aatctgctct ttctatttca
     8701 gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat gaggatggtg cttttggaga
     8761 ttggttgcca aaccaattct atggtctcca tgttcgtcca gatttgaaag tcggccagat
     8821 tgcgactaat actcatacac tctttgcagg aacttgcgag gtgaagatcc gtttcaaagg
     8881 caaaggtggc cacgcagctt ttcctcatga agccaatgac gccttggtgg cggctagtta
     8941 ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc aacccaatcg agggagcagt
     9001 ggtgaccttc ggcgtttttc aagctggaac caccaacaat gtcatcacag acacagcttt
     9061 tttacatgga actattcgtg ccttgacaca ggacatgagt ctcttggtgc aaaagagggt
     9121 aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg gaagtcgaag tggaactcaa
     9181 acaaggtgga tacctacctg ttgagaacaa tccagccttg gcgcgtgaac tgatggactt
     9241 ctttgacgaa aaagacggaa tcgagttgat tgatatcgaa cctgctatga caggcgagga
     9301 ctttggttat ctcctttcaa aggttgatgg cgtgatgttt tggctaggta tcgatagtcc
     9361 ctacgctctt catcaccctc aaatgagtcc taaggaagaa gtcttagcta ttggggtggc
     9421 tgcggtgtct agtttcctga aaaagaaggc agcagaatag agggcttgtc tatgaaatcg
     9481 gaattacgca agcaagtctt gcatgaaatg aaggctatat ctcaagaaca aaaacagttt
     9541 atagatcaaa ctttaaccga gcggctttta caccatccct tctatcaaga agccaaggtc
     9601 atcgcaacct atctctcttt tcctcatgag tttcaaacgc aggaactgat tgagcaggcg
     9661 ctgaaggacg gcaagaaggt tttaataccc aaaacttatc ccaaggggcg catggacttt
     9721 gtggtctatg atccgcaaca gttggtaaaa acttcctttg gattactgga gccacaggga
     9781 gatttggaag tggtggatgc atctcagatt gatttgattc atgttcctgg cctggctttt
     9841 acgacgaaag gatatcggat aggatacggt ggaggctatt atgaccgcta tctggaacat
     9901 ttttctggtc gtactttgag tacgatatat ccttgtcaaa ttcaggactt tatacctgaa
     9961 tttgacaagg atattcctgt tcaggaggta ttaattgatg aaggaaatct ttgatagacg
    10021 ttaccctgtg acgagtttct tcctcttagt gacggccttg gtatttttac taatgttggt
    10081 cactgcaggc ggaaactttg acagggcaga tacattattt cgatttggag ccatgtatgg
    10141 gccagctatt cgcctctttc ccgagcaggt ttggcgtctc ttgtctgcca tttttgttca
    10201 tattgggtgg gaacatttca ttgttaatat gctttcactt tattatcttg gaaggcaggt
    10261 agaggagatt ttcggttcta agcagttttt ctttctctat ctcttatcag gaatgatggg
    10321 caatctcttt gtttttgtat ttagtcctaa atccttagca gcaggcgcct ctacctctct
    10381 ttatgggcta tttgccgcga ttattgttct tcgctatgca actcgcaatc cttatatcca
    10441 acagctaggg caatcctatc tgacactttt tgtggttaac attattggaa gtgttctgat
    10501 tccaggaatc agcctagcag gccatatcgg tggtgcagtt ggtggcgcat ttctagcagt
    10561 tatctttcca gttagaggag aaaaacggat gtataacacc agccagagat taggagcggt
    10621 agtcttgttc gtaggactcg ccattttgct tttctacaag ggaatgggaa tgtgacgact
    10681 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaagcact
    10741 gctttgaggt tgtagataga actgacgaag tcagctcaaa acatggtttt gaggttgtag
    10801 atgaaactga cgaagtcagt aaccatatat acggtaaggc gacgctgacg tggtttgaat
    10861 ttgattttcg aagagtataa tatgtaaact tgaataagaa aaaagctact taaaaaatga
    10921 gtagctttta atgtgttttg gaaccattcg aaacaacaca gctctaaaat agttattagc
    10981 gttgtggagg ttctgcaatg cctcccccag tgtttccaag ataattccca ttttcgtcaa
    11041 acacatctcc attgctctca ttatgataag tatctcttac atgtccacta gcatcaatat
    11101 tcttatattt tttatagtag ccattatttg ctccgctgtt tgaatttcta gatgaatatt
    11161 gttctgatga tccaccattt gttgaactat ctcctgaacc agaataatct tgacctccat
    11221 aattattcga atatccatta gtttgttcag atgaactata atctacattt gaattggaag
    11281 atccattata agactcatta gaagcaccac tagaagaatt actttgacta gaagattcct
    11341 ttgctttttc agcagctttt tcttcttctt tcttcaaaag ttcgatttgt ttttgatatt
    11401 tatcaacaag atcatttaga gatttaagag tttcttccaa attctcttgt ttaaaagttt
    11461 catcaacttt tttgataaaa tcaatttgtt ttgtaatttc tttcacattt gtttcaagag
    11521 ttgctttatc tttaaacttc tcatcagaat ctttaacatc ataagccaaa cctttttgca
    11581 aatgaaaatc tacaattgct ttagatgatt ctttgacttt gttattaaga tagtctttac
    11641 ctgcatcggt tttaagtgaa gtttcagata gttcttttaa tttagaaata gattcatctg
    11701 aagatgcatc aaatgattca aatagtttat caacttgttc tttgtctgat ttgctatctt
    11761 tttctaattg tacaattttt gcttgttgtt ctgcttgttg ttggttatat gaataccatc
    11821 caaaccctaa taccaataca acaccaactg caactgatga aatgattact tttttattgt
    11881 tttcgataaa ttctacaaat ttgttctcca taatctttta ctttgatagt gtccgcaatt
    11941 actttaaaat taaaatt
//
LOCUS       DAVMBH010000056        11912 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVMBH010000056 DAVMBH010000000
VERSION     DAVMBH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.056"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(38..1240)
                     /gene="rpsA"
                     /locus_tag="VYP30_001794"
     CDS             complement(38..1240)
                     /gene="rpsA"
                     /locus_tag="VYP30_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1808742.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1402..1473)
                     /locus_tag="VYP30_001795"
     tRNA            complement(1402..1473)
                     /locus_tag="VYP30_001795"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1439..1441),aa:Gln,seq:ttg)
     gene            complement(1483..1563)
                     /locus_tag="VYP30_001796"
     tRNA            complement(1483..1563)
                     /locus_tag="VYP30_001796"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1527..1529),aa:Tyr,seq:gta)
     gene            complement(1613..1843)
                     /locus_tag="VYP30_001797"
     CDS             complement(1613..1843)
                     /locus_tag="VYP30_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1808743.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(2011..2655)
                     /gene="pcp"
                     /locus_tag="VYP30_001798"
     CDS             complement(2011..2655)
                     /gene="pcp"
                     /locus_tag="VYP30_001798"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1808744.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2670..3593)
                     /locus_tag="VYP30_001799"
     CDS             complement(2670..3593)
                     /locus_tag="VYP30_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1808745.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3590..4279)
                     /locus_tag="VYP30_001800"
     CDS             complement(3590..4279)
                     /locus_tag="VYP30_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1808746.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4344..5048)
                     /locus_tag="VYP30_001801"
     CDS             complement(4344..5048)
                     /locus_tag="VYP30_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1808747.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIIDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDILTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(5104..6126)
                     /locus_tag="VYP30_001802"
     CDS             complement(5104..6126)
                     /locus_tag="VYP30_001802"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1808748.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6258..8729)
                     /gene="parC"
                     /locus_tag="VYP30_001803"
     CDS             complement(6258..8729)
                     /gene="parC"
                     /locus_tag="VYP30_001803"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1808749.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9149..11092)
                     /gene="parE"
                     /locus_tag="VYP30_001804"
     CDS             complement(9149..11092)
                     /gene="parE"
                     /locus_tag="VYP30_001804"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1808750.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11228..11869
                     /gene="plsY"
                     /locus_tag="VYP30_001805"
     CDS             11228..11869
                     /gene="plsY"
                     /locus_tag="VYP30_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1808751.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3423 a         2706 c         2099 g         3684 t
ORIGIN      
        1 tttagtaaac aaaggatttt gtgaattttc aatttgatta aagttcgata tcaccaaaca
       61 aatcagccat tgaaaatcct gtttgtgttt ctggaagttc gaaatcacgc ttttcttgac
      121 gtcttggacg acgtggacga gcagcacgtt tttcttcttt ttgtccttct tcttgggctg
      181 gacgttcttc aagagcttta atagaaagtg acacgcgttc tgcatctgcg ttaacttcaa
      241 gaactttaac ttgaacttct tgaccaactt taagagcttc ttttggattt tcaatccgtt
      301 tgtgtgaaat ttgtgatacg tgaacaagtc catcgatacc tggcaatact tcaacaaatg
      361 caccgaagtc agtcaaacgt ttaactgttc cttctactac atcaccttta gccaattttt
      421 gctcaacgcc atcccatggt cctggtactg ttgctttaag tgaaagtgat acacgtcctt
      481 cttcttcgtt aagatcaagg attttcactt caatttcttc accaacagtt acaactgatt
      541 ttggtgatac gttacgttca tgtgacaatt cagtcaagtg aaccaatccg tcaacaccac
      601 caaggtcgat gaaagcgccg aagcttgtga tacgagcaac tttaccagtt acaacatcac
      661 caacagccaa tttaccgaat acttcagcgc gagctgctgc agtagctgct tcaacaactt
      721 cacgacgtga aaggatgaag cggttttctt tagcgttaac ttctttgatt ttagtatcaa
      781 attcttgacc tacaaaacgc tcagcgttac gtacgaaacg agtatccaac attgaagctg
      841 ggataaatcc acgaacacct tcaaattcta ctgaaagtcc acctttaacg gcacgcgttc
      901 ctttaacagt aacaacttct tcttcgcgac caacaagttt gtcccatgct ttgcgagctt
      961 caaggcgttt tttagataca aggtatgtaa ctgtatcagt atctttacca actacttgac
     1021 gaagtacaag aacatccaat acttctccta ctttaacaaa gtcattgata tctgcatcac
     1081 gatcgtttgt caattcgcga agagtcaaga caccttcaac accagttcca gagattgcaa
     1141 cgttagcttg agtcgcatca actgtcaata cttcagcact aacaacatca ccagtctcaa
     1201 cttgactaac gctatttagc aaatcttcaa attcgttcat ctaaaaaatc ctccaacaat
     1261 caagtttttc ttaaacttga catacttata atttttttcc taagcacccg caaggacatg
     1321 ttcatatcat tcacgtcttt caattataaa aataaaatac cctaagatat tttgcttttt
     1381 atcttgatta ttacctaaga actggggtag ctggattcga accaacgcat gagggagtca
     1441 aagtcccttg ccttaccgct tggctatacc ccattaatga aatggagaga gagggattcg
     1501 aacccccgaa cccgaaggag cggatttaca gtccgccgcg tttagcctct tcgctatctc
     1561 tcctacaatc aatatggact attatatcat gaaaatttca aaaaaacaag acttattttg
     1621 ctaaattata attttcaatc aaaatttcca cagctttttc caatttttta taaaaactat
     1681 cgacattccc attctttata atggcaaatt gtccgtctaa ttcggcaatt tctccgataa
     1741 cttttttacc gatagtcaat gtataacctt caaaactgtc tttaccaaca ttaactttgg
     1801 catccgctac ttgaatttcg atttttttat ctttcttgct catttcatac ctctcttcac
     1861 tttttctatt ttacaagaaa atcctaaaac tagcaagaaa aaactctata tcaggcttct
     1921 ctgatataga gttttatgta aacaacctca atcgatttag catagctaat agttagtaaa
     1981 caagcataat tgactatcct ttttaggtta tcagtgagtc tcaccgccta ctaactgcaa
     2041 atccttatct ttgtagtcta caatagcttc aatagctacc tctatgcctc ttacaatatc
     2101 acatagactc attcctgcag tattcggctt atttactact tgttccatca tatatggaat
     2161 atgcatgaaa cctgctctca tattagggaa ttttttatcc actaaataaa gagcttggta
     2221 catcaaatga ttgcaaacaa aggttcctgc actattggat acaactgccg gaagtccctg
     2281 ttttttgata gcttgtacca tcgctttgat aggtaaacta ctaaaatagg ccgatgctcc
     2341 atcaatacga atcggtgtat caattggttg attgccttcg ttatcaggta tgcgagcatc
     2401 atcttgatta atagccactc gttcaggtgt taagccggtc ctgccgcctg cttgtccaat
     2461 acaaagtaca gcatctggtt gatatcgtaa tatttctgcc tctaaaactt ctgacgactt
     2521 ataaaaaacc gttggaattt ctacccagcg aacttcagcc ccattaatct cagatggtaa
     2581 taattttaca gcctccaaag ctggattaat cttttcacct ccaaaaggat taaaacctgt
     2641 aaccaatatt ttcattttat tttcctttac taaaatgcga gaaagtacat taagaatatg
     2701 tgaataacaa tcattactag agcaacacct gcttgagcct ttataacgcc attctgatct
     2761 ttcatatcca tcaatgctgc tggtagagcg ttaaaattag cagccattgg ggtcaataag
     2821 gtcccacaat aacctgctgt catggcaaga gcaccagcca caattggatt agctcccaga
     2881 gcaaatacaa agggaactcc aacacctgct gtaataacgg tgaatgctgc aaaagcattt
     2941 cccataatca ttgtgaatag aaccattcca agaacatagg ccaaaactcc tataaagcga
     3001 ctatctgaag gaacaatacc gctaatcaga tgagagataa catcaccaac acctgctaca
     3061 gtaaaaatag cccccaaagc ccctaataat tgaggaacaa tcccacttgt tgaaacttgc
     3121 tgagtcattc gattattttc tgataacaga ctcttagggt gactattggt aatcacaaga
     3181 acagaaattg tagcaaacaa ggcggcaagg ctaatcgaaa tcttgctaaa ttctggaatc
     3241 atttgcgcta agaccaacgc aagtattgcc atcagcataa ctggaataaa aattttattt
     3301 ttcaacctgt tagattcaat attggctttc atttcatcta aggatggcaa ggttccgata
     3361 cggacttgct taaacaatgt taacagcgat aataggatta caataatacc aatactcata
     3421 tttggcatat aggaaccacc tataaacgta atagacaata gagtccaaaa tgcagatgtc
     3481 ccaagtcgaa ctgggtttgt tttatcttta taactacaat aggctgtatg gagaaattga
     3541 caaccaatca caatataggt caactctaat agttgctttg ccaactctgt catttttgtt
     3601 ctcctcccct agtctttttt gatatcaatt ttttatcaaa taaataattg taaatcccca
     3661 ctacaataag tgttataaca gcaacaataa tagatgtaga agcaatccct gcataattgc
     3721 tttcatagcc taactgatct aatgttcccc ctatcaagag gactccccca gcacctacaa
     3781 acgtattttg agcaaagaaa tttccaaaat tttcattcgc agccgcacgc gcttttattg
     3841 tctcatcttc aacctctgtt aactttctac ctaattgaga ctctgcagct gcttctccca
     3901 taggttgaac caaaggtctg acaaactgag ggtgtcctcc tagacgaatt gaaaagaaac
     3961 cagctaactc tcgaataaag aaataaactg tatagaagtt tccaactgtc agacctttaa
     4021 tctttcgaat caaatcgatt gatcgttgct tgagtccaaa ggtttctgac agccccacaa
     4081 gaggcaaggt aaccataaaa atcgtgagca ctcgctgatt gctaaattct tttcccaaaa
     4141 tctccaaaaa ttcaacgaga gaaacacctg aaactaaagc tgtaaccaaa ccagctaaga
     4201 ctactgttgc aattgtatca aattttaaaa taaaacccac aacaatgatt gctattccta
     4261 ttaatctaat ccactccata tcaaactcct ttatattcaa aatgacagta tttttaaaat
     4321 tttatcaaga tcaataccat ttcttattta atgtgttttt ctagttcttt ttggtatttg
     4381 ctattggatt ccaatttttc tttttgccat tttttaaaaa cctcgttata ttcttttgtt
     4441 gtaagaatat ctttttgcaa tttcattcct ttaaagatat atggatcccc cttaatacca
     4501 acttgtgagt atggttttga gaatggtact acgttactta caactggaga accaccagat
     4561 gaagctgttg gcatcaataa tgaactatct gtcgaccaag cttgagcttt ggcatatttt
     4621 tcatatcttt tctctaggtc agtggtctca gaaacagcat cttctaacaa tttcttatat
     4681 ttatccaaac caggtttagc tacaacatcc ttatcttttc ctttcgtaat accaaggtgt
     4741 ttcatggcag aaccagattt tggatctata atattcaagt aagacgctgg atcttgatag
     4801 cttggagccc atcctgtact attcaaatca tagtcttttt gagaaggagc aacattgccg
     4861 tatttatcat tttccatcaa accatcaata acatttccaa taacgtctgt cgtcgatgtt
     4921 cgagtcgcta tactgtagcc caatgatgct ggatctactg catagacata agaaaatgtt
     4981 gtcggtgcat ctgcttcttt atcagttttt ccacaagcca ctaaaatagc tgacgtgctc
     5041 aggaccactc ctgctgttaa gagccacttt ttctatttca taaaaaatct cctttggttt
     5101 attttaatct acttttacaa tccaaccttc tggcgcttca atatcgccaa actgaatacc
     5161 cgtcaattca ttatataatt tacgcgtcac aggacctact tctgtttcac tatagaatac
     5221 atggaaatca tcaccatgtt gaatacctcc aattggagaa ataaccgctg ctgtaccaca
     5281 ggcacctgcc tctacaaaac ggtcaagatt atcaattgga acatcaccct caataggagt
     5341 taatcccaag cgatgttctg ccaaataaag caaggaatac ttggtaatag atggcaagat
     5401 agatggactc aatggtgtta caaattcatt atcagctgta attccaaaga agttagctga
     5461 tccgacttct tcaatctttg tatgagttga tgggtccaga tagataacat ctgagaaatg
     5521 acgtgacttg gccatttttc ctggtaagag acttgcagca tagtttccac caaccttagc
     5581 cgcacctgta ccatttggtg ctgcacggtc gtactcatcc tgaatcaaga agttggttgg
     5641 gaccaaacca cctttaaagt aatttccaac tggcatagca aagatggtga aaatgtattc
     5701 ttctgccggt tttaccccga taatatctcc gacaccaatc aaaagagggc gaagatataa
     5761 ggttccacct attccgtatg gtggtacgta ttcttcattc gcacggacaa ctgctttaca
     5821 agcttctaca aacatgtctg tcggaacttg tggcatcaag agacggtcac atgtacgttg
     5881 caggcgttta gcattttcat caggacggaa cagttgaaca ctgccatcct tagtacgata
     5941 agctttcaaa ccttcaaatg cttgttgtcc atagtgaaga cttggagaag actctgaaat
     6001 atgcaaagtt gcatcctctg taagctctcc ttgatcccat tgtccatttt tgaaatgagc
     6061 aagatagcga taaggtaatt tcatatagga aaaaccgagg ttttcccaat caatcgttac
     6121 tgtcatattc cactccttat tctaaaaacc tatttcttat attctacact atttttctaa
     6181 aatagcaagt atattttgta attttcagaa aatttctcca ataaaaacca gctcttagaa
     6241 ctgattcttc atttcactta tttatcttca gtaactactt cctgaagata agcgtcaaaa
     6301 acttcttcat ctgaaatcgt gtcagaaatg aagcttccat tgctagtgcg ttctgacaag
     6361 ttcaagtctt gcaatcggct ttcatagatt gttcctttat tggattggac aagcagagtt
     6421 tggtcgttca catccacttc cgtactgaag aaatcgccaa caaatccttg ctctgcaact
     6481 gctcctgcca agaagacacg atgcggtttg tttttcaact cacgcaagac ttgtaatcct
     6541 cgtttggcac ggctggttgc tagaatttcc tcaatggaaa cacgtttcaa gcttccacgc
     6601 tgggtcaaga ggtagaagga cgaagtatta cagataaagc cagattggag gacatcatct
     6661 tctttcaaat tcatagcctt gacacctgct gccttagcac cgacaaccgg aacctcttcg
     6721 atattgaaac gcagggcata accattttga ctaaccaaga caacatcatc tagtttaatc
     6781 ggagccactg ctacaatctg atctgtatcg tctttgagct tagcatactt gacagactta
     6841 gatctatagg tccgccatgg agtgaattct tttcgctcta cccgtttgat ttgaccaagg
     6901 cgagtcactg caaagtaggt tgtcgcatcg tcaaactgat ccagtacttc cacataaagg
     6961 atttcttcat tcgtttcaaa gtttgtgatg gtttggctca gatgctctcc gatgtccttc
     7021 caacgaatat ctgccaactc atggattggt ctgtagatga catttccaag acttgtgaac
     7081 atcaagaggt gctgggttgt cttggcagat tgaacaaaaa tcaaacggtc atcatcacgc
     7141 ttgccaattt cttccaaggt ggaagccgca aaggaacgtg gactggtacg cttgatgtaa
     7201 cctgccttgg tcacgctgac gtaggtatct tcctcagcga taagactagc tgtatcaatc
     7261 tcaattgctt tcgcagtgtc ttctaaagaa ctcaaacgag gagttgcaaa tttcttcttg
     7321 acctcacgaa gttctttctt catgagattg tacatagtcc tttcatcacc gataatagcc
     7381 gccagcatag caatcttctc acgaagctct gcttcttctt cctgcaagac aaccacatcg
     7441 gtattggtca aacggtacag ttgcaaagtt acgatagcct cagcctgttc ttccgtaaaa
     7501 tcatagctaa ctttgaggtt ttccttggcg tccgccttat tctcagaagc acggataaga
     7561 gcaatgactt catccaaaat cgaaatcaca cgaatcaaac cttcgacgat atggagacgt
     7621 ttctcagcct tttctttgtc aaagcgtgaa cgcgccaaaa tcacttctcg acggtgagcg
     7681 atgtagctag acaggattgg aacaatccca acctgacgag gtgtgaaatt gtcaatcgcc
     7741 accatattaa agttgtagtt gatttgtagg tcggtgtact taaataagta gttgagaaca
     7801 agctcagtat tagcgtcttt cttaagttcg atagcgatac gaagaccatc acggtcagac
     7861 tcatcacgaa cctcagcaat cccagctacc ttgttattaa cacgaacatc atcgattttc
     7921 ttgactagat tggccttatt gatttcataa ggaatctcag taataacgat ttgttcctta
     7981 ccacctttta gcttttcaat ttcagtcttg gaacgaacaa ccacgcgccc tttcccagtc
     8041 tcataagctt tcttgatttc atcacgaccc tgaataatag cccctgtagg gaagtctggt
     8101 ccaggcaaga attccatgag tttatcaatc tttgcagttg ggtggtcaat catgtaaact
     8161 gcagcatcta tgacctcagc taaattatgg ggaggaatgt ctgtggcata accagccgaa
     8221 atcccagtcg aaccattgac caagaggttt ggaaaggctg ctggcaagac cgttggttct
     8281 ttctccgtat cgtcaaagtt ccatgcaaaa ggaactgtct ttttctcgat atcctgaaga
     8341 aggtagcctg caatttcaga caaacgtgcc tcagtataac gcatagccgc aggaggatct
     8401 ccgtccatag aaccgttatt accgtgcatt tcaactagaa tctcacgatt tttccagttc
     8461 tgtgacatac gaaccatggc atcatagata gaagaatccc cgtgtgggtg gaaattcccc
     8521 atgatgttcc cgactgactt ggccgactta cggtagctct tgtcaaaagt attgctatcc
     8581 ttattcatag aataaagaat acggcgctga accggcttca acccatcacg aatatctggc
     8641 aaagcccggt cttgaataat gtacttggag tagcgaccaa agcgctctcc catgatgtcc
     8701 tccagggaca tgttttgaat gttagacata agatacaaag cccataaaat accaagtgaa
     8761 aatagaaaat tcttgaagta agcaaactca caagagaatt tatctttttc acacagtatc
     8821 tagggcgtgt tcaactcctt tcaaagaatg tagagtaggt ttttatgcag taaaagatat
     8881 tttacgggaa ttcctcccgt gttcagttac gataagtaac caaactatcc tgtttgtatt
     8941 tttcaatatg aaaatctggt tttccaaaat tagtcttagt ttgtgtctta gccgctccct
     9001 taagcgcctc tttgagataa gcactcatag cagattcttc attaataatc ctgcaatttt
     9061 ttcaaaccaa gattttcaaa ctgctttttc acatagtcat tcacatccga ctctaatttc
     9121 cagtttacta acatattatt ttctttcatt aaaacactgt cgcttcttct agcgtaaact
     9181 tgacattatc ttcaatccat ttacggcgtg gttctacctt atctcccatg agaacattga
     9241 cgcggcgttc ggcgcgcgct aaatcttcaa ttgtgacacg gatgagggta cgtgtttctg
     9301 ggttcatggt tgtttcccag agctggtccg cattcatctc accaagtcct ttgtatcgtt
     9361 ggagggtagc gcctttaccg aactgtttac ggagttcttc tagttctccg tccgtccaag
     9421 cgtaggccac ttcttctttc ttgcctttac ctttggacat cttataaaga ggtgggaggg
     9481 caatatagac atgacctgcc tcgactagcg gacgcatgta acggtagaaa aatgtcaaga
     9541 gcaaggtctg gatatgggca ccgtcggtat ccgcatcggt catgataatg atcttatcat
     9601 agttggcatc ttcaatagag aagtctgctc caacacccgc accaatggta taaatcatgg
     9661 tattgatctc ttcatttttg aggatatccg ccatcttggc cttggctgta ttgacaacct
     9721 taccacgaag aggtagaata gcctggaact tgcggtcacg accttgtttg gcagaaccac
     9781 cggcagagtc cccctcaact agatagagtt cattcttagc aggattctta gattgggctg
     9841 gggtcaattt cccagacaac aagcccttat ctttcttgtt tttcttccca tttcggctct
     9901 catcacgcgc cttacgtgct gcttcacgag catcacgggc cttgatagcc ttgcggatga
     9961 ggttagaagc taattcccca ttttccataa ggaaaaaggt caacttatca gccactattc
    10021 catccacaac tgggcgagct agggggcttc ctagtttatc cttggtctgt ccttcaaact
    10081 gcaagtgttc ttcaggaact aagatagaaa gaacggccgc tagtccctca cgatagtctg
    10141 aaccttcaag gtttttatct ttttccttga gaagacctgt tttacgtgca tagtcattca
    10201 tgaccttggt aatggcagac ttgagtcctg tctcgtgcgt tccaccgtcc ttggtgcgaa
    10261 cgttattgac aaaggataga atgttatctg agaatccgtc attgtactgg agggctactt
    10321 ccacttgaaa accattgtct tccccttcaa agtaaagaac tggcgtcaag atttccttat
    10381 cttcgttgag ataagaaaca aaatcttgta ctccattctc atagtggaac tcaatcgctt
    10441 catctgttcg cttgtccgtt aaagacaagg tcacattttt caagagaaag gctgattcat
    10501 taaggcgctc tgaaatggta ttgtacttga aatctgtcgt agaaaagata gtcgcgtcag
    10561 gcataaaagt aactttggtg cctgttttag acttgggtgc tgtaccgatt ttcttcaaag
    10621 tcgtgacagg ttttccacca ttttcaaaac gttgcttgta aactgcgcca tcacgggtaa
    10681 tttcaacttc taaccagcta gaaagggcgt taacaacgga agaacccact ccgtgaagtc
    10741 cacctgatgt cttatagcca ccttgaccga atttccctcc ggcatgaaga atggtaaaga
    10801 taacctcaac agttggaatt cccatagcgt gcatacctgt cggcatccca cgtccatggt
    10861 cttgaaccgt tagactaccg tctttattga tagttacatc aatacgatca ccaaacccag
    10921 acaaggcttc atcgactgca ttatcaacga tttcccaaac taggtgatga agaccagcgc
    10981 catcggtcga tccaatatac atccctggac gttttcggac cgcatccaac ccttctagca
    11041 cctgaatagc atcatcatta taattgttaa tattgatttc cttttttgac acaaggaacc
    11101 tcctattcgt tcatctttac tattctacag gttttccaag gattttgcaa aatttttctt
    11161 tctccgatgt gacaatttca gcagagattc tctgcttttc tttcccaatt catgatataa
    11221 taggagtatg attacaatag ttttattaat cctagcctat ctgctgggtt cgattccatc
    11281 tggtctctgg attggacaag tattctttca aatcaatcta cgcgagcatg gttctggtaa
    11341 cactggaacg accaacacct tccgcatttt aggtaagaaa gctggtatgg caacctttgt
    11401 gattgacttt ttcaaaggaa ccctagcaac gctgcttccg attatttttc atctacaagg
    11461 cgtttctcct ctcatctttg gacttttggc tgttatcggc cataccttcc ctatctttgc
    11521 aggatttaaa ggtggtaagg ctgtcgcaac cagtgctgga gtgattttcg gatttgcgcc
    11581 tatcttctgt ctctaccttg cgattatctt ctttggagct ctctatcttg gcagtatgat
    11641 ttcactgtct agtgtcacag catcgatcgc ggctgttatc ggggttctgc tctttccact
    11701 ttttggtttt atcctgagta actatgactc tctcttcatc gctattatct tagcacttgc
    11761 tagtttgatt atcattcgtc ataaggacaa tatagctcgt atcaaaaata aaactgaaaa
    11821 tttggtccct tggggattga acctaaccca tcaagatcct aaaaaataaa acgccagttc
    11881 tgtactgccc ccaaacagtt agacaaataa tt
//
LOCUS       DAVMBH010000057        11616 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVMBH010000057 DAVMBH010000000
VERSION     DAVMBH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.057"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            123..881
                     /locus_tag="VYP30_001806"
     CDS             123..881
                     /locus_tag="VYP30_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808752.1"
                     /translation="MALVEFKNVEKYYGDYHAFRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKAVLENVT
                     LAPIEVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            921..1685
                     /locus_tag="VYP30_001807"
     CDS             921..1685
                     /locus_tag="VYP30_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1808753.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDTFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            1698..2375
                     /locus_tag="VYP30_001808"
     CDS             1698..2375
                     /locus_tag="VYP30_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808754.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAVGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPFYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPGFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            2385..3044
                     /locus_tag="VYP30_001809"
     CDS             2385..3044
                     /locus_tag="VYP30_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808755.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEVGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            3293..4483
                     /locus_tag="VYP30_001810"
     CDS             3293..4483
                     /locus_tag="VYP30_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1808756.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKIIHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(4804..5685)
                     /locus_tag="VYP30_001811"
     CDS             complement(4804..5685)
                     /locus_tag="VYP30_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1808757.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(5826..7154)
                     /gene="vncS"
                     /locus_tag="VYP30_001812"
     CDS             complement(5826..7154)
                     /gene="vncS"
                     /locus_tag="VYP30_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1808758.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENSLTFFIDFPKVVQD"
     gene            complement(7151..7807)
                     /gene="vncR"
                     /locus_tag="VYP30_001813"
     CDS             complement(7151..7807)
                     /gene="vncR"
                     /locus_tag="VYP30_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1808759.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKATKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(7856..7939)
                     /gene="pep27"
                     /locus_tag="VYP30_001814"
     CDS             complement(7856..7939)
                     /gene="pep27"
                     /locus_tag="VYP30_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1808760.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(8119..9498)
                     /gene="vex3"
                     /locus_tag="VYP30_001815"
     CDS             complement(8119..9498)
                     /gene="vex3"
                     /locus_tag="VYP30_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1808761.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(9550..10197)
                     /gene="vex2"
                     /locus_tag="VYP30_001816"
     CDS             complement(9550..10197)
                     /gene="vex2"
                     /locus_tag="VYP30_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1808762.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(10210..11487)
                     /locus_tag="VYP30_001817"
     CDS             complement(10210..11487)
                     /locus_tag="VYP30_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808763.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKGSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVTLCFLFLFRKSPKEILSSIS"
BASE COUNT         3260 a         2606 c         2202 g         3548 t
ORIGIN      
        1 ctgtcccgat cgatttttcc tgttcttatt tcactatagt gaattttttc agatatgatt
       61 tgacaagaac attcttttat tgtagaaccg tgttataaaa tataacacaa tagagatctc
      121 tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac cacgcattcc
      181 gcaacatcaa tctccgtttt gaaaaaggac aagttgttgt cctgcttgga ccttctggct
      241 ctgggaagtc cactcttatc cgtacgatca atggtttaga gactgttgac aaaggaagtc
      301 tcctagtcaa tgggcaccaa gttgctggtg ccagccagaa agatttggta cctcttcgca
      361 aggaagtcgg catggttttt caacatttta acctttatcc acacaaagct gtgttagaaa
      421 acgtaacgct tgcacccatt gaagttctag gaattgataa aaaagaagct gaaaaaaccg
      481 cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat cccgccatgc
      541 tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg catccggaac
      601 tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga gatgttctag
      661 cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc cacgaaatgg
      721 gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa gttttagtag
      781 atacgacaga tgtcgataac ttttttgaca atccaagcga acctcgtgcc caacaattcc
      841 tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc tatgaaaaaa
      901 aattcttttt atcagcatta ttgattagcc ttttcggcct tgctgctgcc aaaccagtcc
      961 aggctgatac aagtatcgca gacattcaaa aaagaggcga actggttgtc ggtgtcaaac
     1021 aagacgttcc caattttggt tacaaagatc ccaagaccgg tacttattct ggtatcgaaa
     1081 ccgacttggc caagatggta gctgatgaac tcaaggtcaa gattcgctat gtgccggtta
     1141 cagcacaaac ccgcggcccc cttctagaca atgaacaggt cgatatggat atcgcgacct
     1201 ttaccatcac ggacgaacgc aaaaaactct acaactttac cagtccctac tacacagacg
     1261 cttctggatt tttggtcaat aaatctgcca aaatcaaaaa gattgaggac ctaaacggca
     1321 aaaccatcgg agtcgcccaa ggttctatca cccaacgcct gattactgaa ctgggtaaaa
     1381 agaaaggtct gaagtttaaa ttcgtcgaac ttggttccta cccagaattg attacttccc
     1441 tgcacgctca tcgtatcgat accttttccg ttgaccgctc tattctatct ggctacacta
     1501 gtaaacggac agcactacta gatgatagtt tcaagccatc tgactacggt attgttacca
     1561 agaaatcaaa tacagagctc aacgactatc ttgataactt ggttactaaa tggagcaagg
     1621 atggtagttt gcagaaactt tatgaccgtt acaagctcaa accatctagc catactgcag
     1681 attaaggagg acaccccatg acagatttat catcttggac agcctatttt caggattttg
     1741 gacaattttt caatggtttc ctcttcaccc ttgccctagc ggttggttcc tttatcctcg
     1801 ctatggtttt gggcatcttc tttggtgcca tgtcaaccag taaacgtcca attttacgca
     1861 ttttagctcg catctttgtt gaattttacc aaaatactcc cctcttggtg cagtttgtta
     1921 ttgtttttta tggcctacct cttatcagtg accatatcat catgattcca ttttattgga
     1981 cagccgttct ctgcgtggga ctctatcacg gcgcttatat cgctgaggtt attcgttcag
     2041 ggattcagtc tattcctagt ggtcagatgg aggccgcctt gtcgcaaggt tttacctata
     2101 tcagtgccat gcgcttgatt atcttgcctc aggccttccg catcattctc cctccattga
     2161 ccaaccaaat tgttaacctc atcaagaaca cctctactgt agctatcatc tctggagtag
     2221 acttgatgtt tgtgactaag tcttggtcgg ctctcaacgg aaactatatc ccaggctttt
     2281 taggtgctgc tcttctctac tttgccctat gcttccctgt tgcccagttt ggtcgcaaga
     2341 tggagcaagc caacaaaaaa gcctattcac tttaggaggt tactatggaa tctattttag
     2401 aagttttaac cccagataac ctagtcttta tctttaaagg atttggcttg accctctata
     2461 tttctctgat tgccatcatc ctctctacta tcatcggtac ggtgctagct gtcatgagaa
     2521 atggcaaaaa tcctgtcttg cgaatcatct ccagtattta tatcgagttt gtgcgcaacg
     2581 ttcccaacct tctctggatt tttactatct ttttggtgtt caaaatgaaa tccacaccag
     2641 caggtattac agcctttact ctctttacat cagcagcctt ggttgagatt attcgaggcg
     2701 gtctcaatgc cgtagacaag ggacaatacg aagtaggaat gtcacaaggc ttcacctcag
     2761 cccaaatcct ctactacatc attctcccac aagccatccg caaaatgcta ccagccatca
     2821 tttctcagtt tgttaccgtg attaaggata ccagtctcct ctactctgtt atcgccctac
     2881 aagaactctt tggagccagc caaattctca tgggccgtta tttcgaacca gagcaggtct
     2941 tcagtcttta catcctgatt gccctcatct acttcagctt taacctagca atttctagcc
     3001 tgtctcatat gctagccaaa cgttggcaac aagctgcaga ataatactct tcgaaaatct
     3061 cttcaaacca cgtcagcttt accttgccgt actcaagtac agcctgcagc tagcttccta
     3121 atttgctctt tgattttcat tgagtataaa cagccactct ccagttcaat tggagagttt
     3181 tttgatgata gtagatattt atagacctca atttgacacc atacattttc tatgataaaa
     3241 tgtaacaaat ttatttacaa caaatcgaaa tctaaatgaa atggaatttt ctatgaaatc
     3301 agtcaaagga ctactcttta tcatagctag ttttatcttg actcttttga cttggatgaa
     3361 cacttctccc caattcatga ttccaggact agctttaaca agcctatctc tgacttttat
     3421 cctagccact cgtctcccac tactagaaag ctggtttcac ggtttggaga aggtctacac
     3481 cgtccacaaa ttcacagcct ttctctcaat catcctacta atctttcata actttagtat
     3541 gggcggtttg tggggctctc gcttagctgc tcagtttggc aatcttgcca tctatatctt
     3601 tgccagcatc atccttgtcg cctatttagg caaatacatc caatacgaag cttggcgatg
     3661 gattcaccgc ctggtttacc tagcctatat tttaggactc tttcacatct acatgataat
     3721 gggcaatcgt ctccttacat ttaatcttct aagttttctt gttggtagct atgccctttt
     3781 aggcttacta gctggttttt atatcatttt tctatatcaa aagatttcct tcccctatct
     3841 agggaaaatt atccatctca aacgcttaaa tcacgatact agagaaattc aaatccatct
     3901 tagcagacct ttcaactatc aatcaggaca atttgccttt ctaaagattt tccaagaagg
     3961 ctttgaaagt gctccgcatc ccttttctat ctcaggaggt catggtcaaa ctctttactt
     4021 tactgttaaa aattcaggcg accataccaa taatatctat gataatcttc aagccggcag
     4081 caaagtaacc ctagacagag cttacggaca catgatcata gaagaaggac gagaaaatca
     4141 ggtttggatt gctggaggta ttgggatcac ccccttcatc tcttacatcc gtgaacatcc
     4201 tattttagat aaacaggttc acttctacta tagcttccgt ggagatgaaa atgcagtcta
     4261 cctagattta ctccgtaact atgctcagaa aaatcctaat tttgaactcc atctaatcga
     4321 cagtacgaaa gacggctatc ttaattttga acaaaaagaa gtgcccgaac atgcaaccgt
     4381 ctatatgtgt ggtcctattt ctatgatgaa ggcacttgcc aaacagatta agaaacaaaa
     4441 tccaaaaaca gagcttattt acgaaggatt caagttcaaa taagtaatca tactctcctg
     4501 ggatttccca ggagaatttt ttatagccaa atgaaataag accggaacga tggaattttg
     4561 gcattcaaat caattgataa gaatatttta tagtggagtg aaataggata cgaacaaatt
     4621 gattaggaaa atcaaatgaa tttatagaaa tcttttagca gttatgttgt cctattctag
     4681 tttcaaaacg ctatagaagc agcattgtgc tagtctagat tcagtttact atactaaaac
     4741 gagtagcttg aaatcaaaaa acccaccctc acaggcaggt tttatctgta ttattcagct
     4801 agattatgct ttaccttctg aaccgaatac gtcgatacgt tcttcaaccg atgcttggat
     4861 agcttttaca ccgtcagcca agaatttacg tgggtcgaag agttttttct tgtcgtattc
     4921 tgcttcgttt gcttcgtagt cacgagcaaa tttacgagtt gcgttagcga atgcgatttg
     4981 gcattctgtg ttaacgttaa ctttggcaac accaagtttg atagctgctt ggatttgctc
     5041 atcaggaata cctgatccac cgtgcaatac gattgggaat cctggaagag cttctgtcaa
     5101 tttttgcaag tggtcaaggt caagaccttc ccagtttact gggtaagggc cgtggatgtt
     5161 accgatacca gctgccaaga agtcgatacc agtttcaacc attgctttag cgtcttcgat
     5221 tggagccaat tcacctttac cgatgattcc gtcttcttca ccaccgatag taccaacttc
     5281 agcttctact gagatacctt tagcgtgtgc tttttcaaca acttctttag ccaatttaag
     5341 gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtataac caacttcgat
     5401 acactcaagt gcatcttcgt agtgaccgtg gtcaaggtgg atagctactg gtacagtgat
     5461 acccattgat tcaacaaggt tagcgatcaa gttgcgagca actttgtaac cacccatgta
     5521 tttagcagca cccattgaag tttggatcaa aactggagct tttttagctt ctgctgcgcg
     5581 caagatagct tgagtccact caaggttgtt tgtgttaaat ccaccaactg cataaccgtt
     5641 gtcacgggct gcttggacaa atttttctgc tgaaacgatt gccattttat caggcctcct
     5701 gtatattttt atgggtcatc ccatttacat tgttcatttt atcacttttt gccaaaaaaa
     5761 tctagttttt cccgcagttt cgattgattt tcttctaact ccatctatgt aaaccctttc
     5821 tctccctagt cttggacgac ttttggaaaa tctataaaga aggttaaact attctcctcc
     5881 atctcgaaac gataagctaa tttttcatgt tctaatagac tcttaaccac aaagagcccc
     5941 ataccagacc ccttgacctt gcgactggca ttgtcagaaa aagactgggc tagtttttct
     6001 tgttcctctg agctacagct attttcgata aaaagttctc cttctctttc tccaattcga
     6061 actaagccac ctggaacaga gtgcttaatg gcattgctga tgagattaga aagaatcaac
     6121 ttcataactg atgggtttag ataagcctgc tgatgggtca aactattgtc tatctggagc
     6181 tctctttcct tggctagcaa ggcataatct ttgaccagat tttgcgtcat ctggaggagg
     6241 tcaattgttt ccctatcatc tcgcaattcc tgcacagaag agagggaaag tatctgcaga
     6301 acatggtgat tgagttcatc cacaatcccc aaggcaactc ccagatactg gtctctatcc
     6361 ttataacgac cgatattctc tctcatattt tcgattagga ttttcaaact agccagcggt
     6421 gttttcaatt catgagaagc tcctcgtagg aattcgacct tcatcttctc cagctggaga
     6481 atggcttcat tcttttcatg caagtccgca ataacagtca agagatgctg gtagaggcta
     6541 ttgatttgtt ccttgagatt acctatctca tccttagaat ccacgcgcaa tcgcacttgg
     6601 gaatccaggt ccatcatccg acgggtcacc cgcttgattt ccaaaatcgg tgcaacaata
     6661 gtccgagcgt agatgtaggc caccaaaagg gaaatcagaa aggaggccag caaggtatag
     6721 ggaagaaact ggagactgat ttgctccgct tccttttgta aatccatgga agctagaaac
     6781 tggagaatca tagtaccacc gtcttgcgtt ttcacctcgc gctcctcaat aaagagagag
     6841 gttgtctggc ggtctgtgtc cagaggaaga ctgtccttga cttctaactt gtcctcggtc
     6901 atctcacctt tgacggtccc cttgatatca ctagtctggg aatacaagtc taacacttgc
     6961 tcgatactct gcctatcttt cccttctagg gactgggcaa tggctgttgc cttttgacca
     7021 atggtttcct gacgatgact cagataagtc gaaggaaaaa gaaaataaat agctaaatga
     7081 aggcagataa ccagaacact aaatatcgag aaggtataga taaatatctt tgcaaataaa
     7141 cctgttcgtt tcattttcgc tccaatttat aaccaacatt gcgcacagtg aggatacaat
     7201 ccaagtctag ctttttccgc aattccttga tataaacatc aataacacgg tcaaagggaa
     7261 cctcatctgt cgctttccag acggcatcga taatctgaga ccgagtcaag gcccggcctt
     7321 catttttcac tagatagtcc agaatttcca actctttggc attgataggc acttcttgac
     7381 ctgcgaggct tgcactgtag ctttcaaagt ccaccttggt agccttgtaa gaaaagattc
     7441 gtcctgtatc gtagtagcgc ttgaaaatcg cgtccaccct cacttttaag agggagaggg
     7501 agaaaggttt ttccagatag ccatctgcca aagaggcaaa ggcactcatc ttgtattcct
     7561 catcctgaaa agctgtcaac atcaagacag gaacctgact ggttttacga atctcagcta
     7621 gaacttctaa gccgttaagc ttgggcatct ggatatccag taaaaccagg gccacctcat
     7681 agctagaaaa ttgctccaga gcttcctgac cgtccgctgc ctcaatagtt tcatagccac
     7741 aatccgtcaa ataatcactg accccctcac ggatcatctc ttcatcttct acaattaaaa
     7801 ttttcatact ttaactgctc tctatttttt atttttctta gaataaatac ctactctatt
     7861 ttctattata gtctcttgct ggccttttgt ctgtaagtaa ctgatcacta gataaaacgt
     7921 tgtgaaattc ctttctcata aattccatag ctttagtata ttatatttaa gcaataaagt
     7981 acaaagaaaa caactgaaag caatgatttt caccactgct ttcggattta ttttgaattg
     8041 ttaaatagcc attcctatcc actattcttg aatagaaaca caagatgcaa tctttattcc
     8101 agactcattt tttcaaattt attcaccatc cagcaagagc tcttttggtt gttttctaag
     8161 gagattgctt gaagcaagcg ccataacgag aaccactaga accaaggcaa ggacaaaaat
     8221 gatgataaag tctgatgtct gaatagaaat gtctaggctc gacaaggtct tgctaaagcc
     8281 atctacttct gcaccaccac caaggttaga ggcttgagcc gccttactag cctgtttggc
     8341 aacacctgaa gtcacattgg caaggacagt gtttccaatt gcacgggcag tgtaattagc
     8401 taggaagtaa gcagaaacta gagcagggat agcaatcaag atagattcgg tgatgaattg
     8461 acccaagata cttgcctgct tgaggccgat agagaggaga attcccactt ccttgcgacg
     8521 ggcgttgatc caaaggctga gcaagagggc aaggaggaga actgagaagc tcaagctacc
     8581 ccagaagagg aggttggcca tcttgtacat accagagata gattgctcaa gagctgggta
     8641 gttagaggag ctcttgacga gtgtgtagct cttccagttg ataccactga tgccattcaa
     8701 ctctttcata acatcatcca agttcttgtc tgctgttaca aagaaggttg cgtccccata
     8761 aatggctgtg tcttctgtgt atccataaag ttttgcagca gtgtgaatgt ctgtaatagc
     8821 tgtgttttcg taaagttctt gtgagtaggt tactgctgac ttattatgac catcaaagag
     8881 tcccttgatt gtcacttcaa ctgtttcctt ggctcctttt tcattatctg catcgtagat
     8941 attagagtcc agtttaacct tgtcccctac tttccagccg tgtttggctg ccaagtcctt
     9001 gtgcaagagg attttatcct tgtcgtcgtt ggttaagtgc tctccttcga ctagtttata
     9061 agaaccagag acaaacttgt cttctttaga ggagtcattg acacctgtaa tcatcaagct
     9121 acttccaaaa cgtttggcac gatcagcagt gagattcttc ttggtttctg gcgtttcaat
     9181 caggtcatat ccagtcaaat ctccgatagc gttgatacgt ttgacataag actcaatggc
     9241 cttgttttcg gtgatttttt tgatgtcttc acccttgata ttcccagcac cgcgaggcgt
     9301 tccttggttg acgcgacgat tgatttgcat ggagaagcta ttggtgatat ttttaaaggt
     9361 ctcctgagaa gccttggcag tagctccctt gattgacaag ccgaccaaac tcaagctcgc
     9421 catgaggaga ataatcagga agatgacaat cgatttgaaa aacttccttg taacataggc
     9481 aaatgcgttg tgtaacatag attccctttc tagattttgt tttaatcatt ctatcaaaat
     9541 aagctcaaat tatttactag tattgcgcgt ttcagtcagt ttcttatcct ttaattcaag
     9601 tgtaatatct gacgcttgtg ccacttcttt actgtgagtt acgacaatca cacatttacc
     9661 tgttttctgg gcaagtgatt tgagtagttc gacaatatct ccagcagttt taggatccag
     9721 atttcctgtt ggctcatcag ctagaataac tggagcttct gagaccaaac tgcgagcaat
     9781 ggcaacacgt tgctgttgac cacctgataa ctggagaaca ttccgcttga tctggctttc
     9841 atccaaacca agctcaagaa gtgtattctt gcttgccttt ttgttgacca atcggatatt
     9901 ttccagcgga gaaagataat ctatcaagtt ataattttga aagaccaggg aaatatggtg
     9961 catgcgatgg taagaatagc ccttcttacg aatatcctct ccttgaaaaa ggatagaacc
    10021 ttcaacagga ctatctagac cagcaagtag ggacaagagt gtggattttc ctgctcctga
    10081 ctccccaata atactgtaaa attttccggg ttcaaaatta taatcgatct gatataggac
    10141 tgcttcagca gtattcttat aacggtaggt aacatcttgt aattgtaata aagtcatgat
    10201 ttctccttct taactaatag atgataaaat ttctttcggt gattttctaa ataagaatag
    10261 gaaacaaagg gttacagata agcaactaag cagaactaga aaaacatagg attctgcaaa
    10321 agataagata ctagttgata aactgcttgc tttggctagt gtatcttgta agcttgcctg
    10381 atctccactt gctagtagag tttggagtag gtaagttgtg attccgtttc ctgcaacaaa
    10441 tgctggaagc aaagctccaa gagataccaa aactacctct aaacagaatt gtaggaagat
    10501 cgagcccttg ccttttccaa gtgcaagtaa aatccccact tcatagaccc gttctctcaa
    10561 ccagagagac aaaaccagaa ttaaggctcc agctcctgct atcaacatcc cataaaggaa
    10621 gatggtcagg aaggtttgga aagttgcaac tgagtctttg atttgttcaa aagccttgtt
    10681 ttccttttcg acttggtagc cttgattttc caaggccaag ttttctacct gcttcatgag
    10741 tccgtccatt tccttaggat tttctacata gaagcgtgct gcactgactt gagcttcact
    10801 attgcccaaa agggtttggc tactttcata gtctgtaaag acttgatttt cactgaagtc
    10861 agaagacaag cctgtgaatt tctcttgttt tttaccagaa aagatgccaa taatctcaaa
    10921 ctctactgtt tgtccttttc cagattcaga ctgaccagca tccaagccaa tcttgtcatg
    10981 aagtgaaaga ccgttcttct tagccaattc ttcgtggata aggattttct tggaatcccc
    11041 tttttgaagg tgtcgccctt cttttagatt gaaagccgaa ctggtaaagg ttacatcctt
    11101 ggatgaatcc tcaagagccg ttaagctaac caagttattg tctgcagctg ataaatcatc
    11161 acgctccacg ctctgctcgc cagtcactgc ttccttgtct tttagttttg cgaccgtctc
    11221 aagttcagga gagacatttt ccagcccctt aatcttgctt acagatgcta ggtctgacaa
    11281 cttgaatgtc tgaccattct ctatcttctt aatagaaaaa gatgtattga gtgatttata
    11341 aagattgctt tctactgttt tgttggactt catcagagtc aaacaggctg aaattccggc
    11401 caataagacc aataaaatca gaaataaaat aaaacttctc agtcgctttc tgctgacata
    11461 agcccaagat ctttggattg gattcatttg tcacctccat atttgtaaga ctattataaa
    11521 acccaaatat gaaatgttta tgaaatacga aaaaaaaata tcgagtaggg gataatctct
    11581 agcccctctc acaccaccgt acgtgccgtt cggcat
//
LOCUS       DAVMBH010000058        11143 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVMBH010000058 DAVMBH010000000
VERSION     DAVMBH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.058"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(1260..2459)
                     /gene="divIB"
                     /locus_tag="VYP30_001818"
     CDS             complement(1260..2459)
                     /gene="divIB"
                     /locus_tag="VYP30_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1808764.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(2469..3527)
                     /locus_tag="VYP30_001819"
     CDS             complement(2469..3527)
                     /locus_tag="VYP30_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1808765.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3531..4883)
                     /locus_tag="VYP30_001820"
     CDS             complement(3531..4883)
                     /locus_tag="VYP30_001820"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1808766.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(4987..5628)
                     /locus_tag="VYP30_001821"
     CDS             complement(4987..5628)
                     /locus_tag="VYP30_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808767.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(5630..7651)
                     /locus_tag="VYP30_001822"
     CDS             complement(5630..7651)
                     /locus_tag="VYP30_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1808768.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(7722..8021)
                     /locus_tag="VYP30_001823"
                     /pseudo
     CDS             complement(7722..8021)
                     /locus_tag="VYP30_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(8585..8977)
                     /locus_tag="VYP30_001824"
     CDS             complement(8585..8977)
                     /locus_tag="VYP30_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1808769.1"
                     /translation="MELDKFKTMMNVRKRMTYFLRFQRMAGSENQVRIDEEAWKLVLP
                     DQWHLSGEHEKAIREGLEIFAHDINSIENERARKYFIIHYCYMRKKTMSECVEMAGTS
                     STSYHRYKQISVLNFARIHQNGELEAYK"
     gene            complement(9014..9271)
                     /locus_tag="VYP30_001825"
     CDS             complement(9014..9271)
                     /locus_tag="VYP30_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808770.1"
                     /translation="MKKARLDSEILEELLEKNKVNYLDANQYAIEIGEILAKVLGAYL
                     SNINQEDVERRKQIGIESAEERKRKRDERIAKFGNPRRRLS"
     gene            complement(9280..10578)
                     /locus_tag="VYP30_001826"
     CDS             complement(9280..10578)
                     /locus_tag="VYP30_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000172765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808771.1"
                     /translation="MTLKGMGYLRKKLANYKMGVDTRYNQYAMQHNDIDVGITIPPQI
                     RQQYRAVLGWTAKGVDSLADRLVFREFANDEFGANEIFAQNNPDVFFDSAILSALIGS
                     CCFVYISQGDDDDAPRLQVIEASNATGVLDPITGLLIEGYAVLKRDDNGYAVLEAYFT
                     SDVTWFYPKDGKPFAIENPTGVPLLVPVIHRPDTVRPFGRSRITKAGMYYQRYAKRTL
                     MRSDVTAEFYSFPQKYVLGLSQDAEAIDTWKATVSSLLTFTKDDEGEKPNVGQFTTSS
                     MSPFTEQLRTAAAGFSGEMGLTLDDLGFVSDNPSSVEAIKASHENLRLAGRKAQRSLG
                     SGLLNVAYVATCLRDEFPYLRKQFNKTVVKWEPLFEADANMLTLIGDGVIKLNQAVPG
                     YMDAETIRDLTGIKGSDKPAPVVKEGADGGRYVSESTPEN"
     gene            complement(10776..11120)
                     /locus_tag="VYP30_001827"
     CDS             complement(10776..11120)
                     /locus_tag="VYP30_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001128258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808772.1"
                     /translation="MPLPTGKIDLNEYGKHLAEKSAEIYKEKTKQAVDAMERHRQECL
                     ARDAKWQAVIDRSDELLKEKKEREHQQEIERLMEEKRKEVDREVSQRLSMPNEHQKKL
                     NKAMSEMLKDLF"
BASE COUNT         3322 a         2481 c         1876 g         3464 t
ORIGIN      
        1 tgatttaata aaaatcatac ctaagttaat gataaataat aagagtccaa gcaatttata
       61 cgatgtgaac aataaaacaa gtaaacctgt aagtgataaa atcgaatttg aagcaattcc
      121 tgctaacata attttcaaaa attgtttttt attttttaaa aattgcaccc cacttaaatc
      181 tacaaaaaaa gccaaattaa acaaaagtag cattattcca caatttggga tctcaatttg
      241 ataattatta gcaattattg catgactaaa ttcatgtatc gttgcagata taataacaac
      301 aagcaaccaa aataaaagaa tgtttagcgt tattggaaag ttttggaaat tagtcaaaat
      361 atccgcccta taaatataca taataaaaca ttgcaaaata agagccaatg ggaaaatacc
      421 aaataggatt ttttcaaaat tcttattaaa tcttttatag tttaattttt cagataatgt
      481 tatattaaag tcccaagata ttttaaaaat atttcttccc tactaacact aataagtccg
      541 atatggtaaa ttcttgacct attagttgct ctaaccattt ttttcctgtt tcccaactaa
      601 tacatgtttc ttactggatg gtatatataa atgatagtgt ccctcataag gagtaggtaa
      661 tatcttaatc ttatcaacaa ttctcataac aaacctaacc tttaataaat aaaagagggg
      721 ttaagtaaaa catactctag tccctcagtc cgcaatcaat aaaataatga ctaattctat
      781 taatctcttg ctgcaagact aatacggaaa atttaaatga ctgtctaaaa tgaaattgaa
      841 aaagcttgat gttagtaaat gaacaaactt caacaaccag caagagcaag gattgctaaa
      901 ccaaatccga tacctgttgc aagtccagct gaaaaatcac taactggtac tgaaatttcc
      961 tcaaataaaa agttatcttg catgattatc actccctatc tttttaacaa caggctactc
     1021 caattaagag aactacccca gttccaagta aaacttcccc caaaaattca ccatctgtag
     1081 gggctacgat ttcttcaatt tcttcaaata agaatacttc atctgacata tgtgttacct
     1141 tcttcatcaa aaattatttt gtaatcgatt acattgcaga tgtaacataa agaaaaacag
     1201 atgtcaaata ttaaacgtaa aaacatggtc actaaagaac tataagagaa aaggtaaacc
     1261 tagcgacgcg atgaacgctg ggtcgtttgg tttcgattgc tctcttcctc ttgttttttc
     1321 tgttcttctt cttgtttttt ctcagcttcc ttggcctctt gtttggcttt ttcctcagct
     1381 tccataatta atttatccgc cacagtgtag ctgtagattc cagcttccat gtcgaccaca
     1441 ctcggttctg acaattgagg cttaatctta ctgtaatatg gcagtttctt actcatttca
     1501 gatagaggaa ccaagacttc gtccgaatca ttcatggtca atcgaattaa atcggatgtc
     1561 accttgcttg gggctaattc caccttttgg atagccgcct tgagttctgg gctaatttga
     1621 gcaagttctg agacaaaaac cttgatttgt tcactatcat taaagagaac tgataaataa
     1681 gtttctggta aactgttcag actcacagaa ctagtctcaa gctgaccact ggaaagaata
     1741 ggataatgat tttcaccaga aatatagtag gccacaatat catattcctt gaccttaata
     1801 gtgaacttag ttggaaattg atagacaagt tgagctgatt caacccaata gttagactta
     1861 atctgctttt catattttgc cttgtctagc agaaggttaa tcgtataatc cgaatcctga
     1921 atgcctgaag cctgtcgaat atcatcagct gtagtttgca ccgttccctc aacacgaata
     1981 tctttcatgg tcgcataagg actgagcaag taggcagaga caatcaataa aagcagactt
     2041 ggaaataaaa tcgtgaaggc tcgcaagata tggataccag gaatctttgc tttggctggt
     2101 ttttcctttg tagccttttt agcaagcttt ttatcctgtt cctccttctc tttagactct
     2161 ggttcttctt tctcttcttt ctctttgtca gcctctgagg atgctacttt ttcttcagac
     2221 tcttccttag ctgattctga atcttcctgg tctgtttcac tctcctggtc ctgtttgtcc
     2281 tctgacttct cagattcttc tcccatccga gcttgtcttt ccttttcctt ctcctcagct
     2341 agagccgctt cttcttcagc cttctttttt agatattctt ggtttcgttt ctgccattct
     2401 gataactctt tcaattcttc gaggatttct ttgtcctcat ttttcttatc ttttgacatt
     2461 tactttcctt atgataaatc ttttttcaac aattgataaa aatctgctag agatttcaat
     2521 tccttagaag ctttcatctt agcttggtaa tcttccttgt gacttagtaa gtgagaaagc
     2581 ttctcttcca aactatccaa ggtcaaatcg ctttcttgaa ggtcttctgc atagcctttt
     2641 tttacaaagt aagctgcatt ttcaatctgg tcaccacgac tagcttcacg accaagcggc
     2701 acaatgacat gcaattttgc tatcgccaag agctcaaaaa tcgtattggc accacctcgt
     2761 gtcacaacaa tatcagccaa ttccaacaag ggttgataga gatcggtcac atagtcaaca
     2821 cgaaaaagat tttggctcaa ctcattcagg ctagaatctc cagttagatt gataatattg
     2881 tagcgctctg ttagttcttt cttatggtct gtcaccaatt ggttaaagac acgagcacct
     2941 gcagaaccgc caacaaacaa tacagtcggc aatttatgat taaagtgggt ttgaatatcc
     3001 accaattcat ctggttctgg atttttttga tctgaaacct tggtcactgc tcccacatgc
     3061 tcaaccttag acaaactcga agcttgctca aaggttgaat acatcttagt cgcaaattta
     3121 taggcgattt tattggccaa gcccatagac aggtcagatt cgtgaataaa gacaggcact
     3181 cctgacacac gcgctgcgat aacaggcggt actgagacaa agcccccctt tgaaaaaagg
     3241 gtctgtggac gaagtcgcaa catgataaag agcgattgga cgattcccca gccaactttg
     3301 aagacgtcca gcatattttg ccaagagaaa tagcgacgca atttcccagt cgcaatggag
     3361 tggaaagtga catccaaacc tgacttaagg atttcttggt gttcgatacc acgcttgtcc
     3421 ccgatatagt ggacttccca accatcttcg atgaacttgg gcattaacaa aagattgagg
     3481 gtaacgtgtc caaccgtccc cccacctgta aagacaattt ttttcatatt ttattctttt
     3541 aactccgcta ctgtgtcgat aaagaggtcg ccacgtactt caaagttagc atacatatcc
     3601 cagctggcat tggcaggact aagaagaacc acatctcctt gagtcgcaag ctcataggcc
     3661 ttgcgggtcg catctgcaat atctgtcgcc tccacataag cgacaccagc cttgtctgct
     3721 gcccgtttga cacgttctgc agattgaccc aggatgacca tcttcttgag tccagtaata
     3781 tctggcacca attcgtcaaa ctcattgcca cggtccaaac cacctgcaat caagacgacc
     3841 ttgctgttgt caaatcctga caaggctttt tgagtagcca agatattagt tgatttactg
     3901 tcgttataga atttaacacc cttgatgtca tccacaaact ggagacggtg tttgacacca
     3961 ccgaaggctg aaagagtttc cttgatggtt tgattgtcca caccacgaag cttggctaca
     4021 gcaatagtcg caagggcatt ttccacattg tggctacctg gaacaccgat ttcattcgct
     4081 gccatgacta cttcaccacg gaagtagagt tgaccatctt ccagataagc tccatcaacc
     4141 ttttcaagtg ttgaaaatgg tacaacagtg gcttctgtct tggaagccaa gtcttttacc
     4201 aagtcttgat taaagttcaa gacaaggaaa tcagctgctg tcatcttgtt ctggatattc
     4261 cacttggctg ctacatattc ctcaaataat ccatgataat cgatatgagt tggcatgagg
     4321 ttggtaataa ccgcaatctc tggatggaat tcttgaacac ccatgagttg gaaagaagaa
     4381 agttccataa caagcgtgtc cttatctgat gctatttgag caacctgact ggcaggatag
     4441 ccgatattcc ctgataaaag accatgttgc ccagcagcag tcaaaacttc cccaatcata
     4501 gtcgttgtgg ttgtcttacc gttcgatcct gtgataccaa taatcggtgc ttctgaaatc
     4561 aaataagcca attccacctc agtcaagact ggaattccct tggccaaagc cttttcaatc
     4621 atgggattgc tgtaggggat acctggattt tttaccatga gggcaaactc ttcatccaag
     4681 agttccaaag gatggccacc tgtaatgacc ttgatccctt cttccagcaa acattgggca
     4741 gctggattgt cctcgaatgg tttcccatca tttactgtca caatggcacc taacttgtcc
     4801 aacaaacgag ccgcagattc accagacttg gccaaaccta aaacaagaac tttcttattt
     4861 ttaaattgat ctattacttt catgtctcga actccatttc tactcctact attttaccat
     4921 ttttatggaa ataaaaaagc cacaaagtgt gtttgtgact ctttcttcta actgaatctt
     4981 accatatcat ctatgtgata aatcggtaac tcgaatgacc tgatccactt gctcccaaat
     5041 cagaggattg tgggtcgcaa taataatggt ccgattcgga ttttttaaag attctaggat
     5101 ggaaagtaat tcctcagaat ttttggggtc taaggaagcg gttggttcat ctgcaagaat
     5161 caaaggcgga tcctttaaaa ttatcttcgc tagtgcaaca cgttgtgctt ctcctcctga
     5221 taactcaaat ataggttgct tcaaatccaa ataagagagg tttacacagt ttagagcttg
     5281 tttcatcaaa gagattttct ctttttcctt caacttttta ccaactaaac ccagattgag
     5341 attctctttg acggtttggc tttcaattaa gccaaaatct tgaaataagt atcccaagta
     5401 atctctaaag aaaacagaag gcttgatgtc cttaagagaa gtgccatcat agatgatttg
     5461 ccctttgtca tatggctcca atcgtccaat catattcaag agtgttgtct taccacagcc
     5521 acttgtaccg attaaggcat aaattttccc accttcaaaa tgaagattcg tatctgaaaa
     5581 tagctgacgg cttccaaatt ttttagatat attctttagt tcaatcatcc tattttcctt
     5641 tcataattgt catagaaaca cgagattctt tctgcgcttg acggtaaagc gtcaaaactg
     5701 cactagctag aaagaccaat aaagtgagca agccaatcac caagtctcga ctgcttaaaa
     5761 taaagagact agcaccaaat acaaaactgg caaattggct aaccatatac tgagcatgtg
     5821 tttcaaaaaa tcgtaaacct gaaattcgtt taatcaagat atctcggcgg aattgctcga
     5881 aatatagaag attgacagaa taaaatagta acaaggaact agctatcccc acaatagctc
     5941 ctaagattaa agttgctgtt tcagtttgaa cttcattata acgagttaga taaacacttc
     6001 ttccttcttt aagataggat acttgctcat aaattccagc tttcttcaag agttctagcc
     6061 cactctcata tcctttgata aagagttgtt ttccagcatt gatagaccaa ctagataagg
     6121 atataaaact atcacctgta gaagtcggcg tgaataccac taaaatcgga tcagtcaaat
     6181 actgagtaga tacgggattc tcaccgttat tataaacaaa ccgcttttct cccattgaaa
     6241 gataactaac gtgcgctttc atctcataat ccaaaggagc acttgcctcc tcaccagatt
     6301 ttccataata actcaatctt tcttcaaaaa ctttcttaag ttctgcttct cgagagcgca
     6361 aatgttctgg gagcaagagg ataaactcac ctttttggag atgggctaac ttctgtttgg
     6421 tctcagcatc taccacgacc ttttccttgt ccaaataact gggactaaca tagagcgtat
     6481 tagcatctgg actataggta tccagtgtct ctccctgttc attttttcct tgtggattgg
     6541 caaaatggag cagattatcc tttacataaa gagcttgttc ttcttcgatt gcttccttgg
     6601 caaaggcata ccacttgctc tgattttctg tatcttttcc tctatcacct aagccaaagg
     6661 aaatctggta atagtctgct ctgtcctgcc atgcttgttt tgaaatttca agttctttca
     6721 atcgttggta agacgtcaaa cctgtcttaa cagcgtagcc tactgtaaaa acagctacta
     6781 actgacacaa tagggttaaa gccatcaagc gtttaagggg taatcttccc ttaataacgg
     6841 gaactaatgc tttgtaactc aaactcatta gataaagaag cattagtaaa attgaaatcg
     6901 ccaataaaaa caacagatag aaactaatcc caaaaccata ggtggctaac aagataggat
     6961 aaaacaaacc ttgactaaaa agaacgactc ccccacctag gaaggaaagg agggctgata
     7021 gaaggagcca cttgatatca gtcgataaag aatgccccat gatggataag agagtctgac
     7081 cagaaaagag ttttatacct gcagctctca tttccttaat ccgagtgata atcactaaag
     7141 caaagaaaga taagccaaat attgctaaac taattaaaat aaggggattt agtaatattc
     7201 gaaaagcaag aaaatagggc ggtatctttc ggtcagcact tgctttataa cccaaatctc
     7261 ctaatttatc ggcaagcttt tctttcgtca aggagcctga caaaaggaga taactattta
     7321 gcggatcact acgttcacga ctttcttggc tagcttcttg gaattctttt ggtaaagttc
     7381 cctgaccata agttgcataa gtaaagtgag tcgtcccatc cttactcggc tctacaattc
     7441 ttctagctat taaactctgt tctgagtttg caaaattctc caattcctgt tcaaatacct
     7501 cacgcgtcgg ttcctgagta tcttttttga cacgaagtaa agaaacggaa tcatagcttg
     7561 catataaata ttgtggcgca cgtaagacaa taatccaagc aaggaagaag ctgagaaaaa
     7621 aagttgataa taatatgaat agtttcttca tagtagactc cttgtaaaca aaattccccc
     7681 tgtaatttct tacaagggga acgatttaaa tcaatgaacg attagtcata atcacagtaa
     7741 aatgctactt gttctcccca tttagtccaa atccatgcat aggaggtttt tccagcagga
     7801 gcttctcctt tatcagaatg accatcccat ctgctcacga tggatgaata atgatatttt
     7861 ttaccatgat agtaatttga aaaagcctaa ccacctcctg aaccttctcc atatgtccat
     7921 actcctccat ctggatattg tacagcagct gatgcagctc ccaataatgt aaaatttgaa
     7981 ataagagcta gagcaagtaa tctatgtttt ttcgttttca ttttattttt tctttcaaaa
     8041 aaagcacacc ttgagcaaca atgcaacaaa ataaatcctc ctctctcttt tattaaaagc
     8101 gctttcttat gtgataagaa taactttttt attatttgtt gtcaaggaaa aaatcgaatt
     8161 ttttagatgt tttactatat tatctctatg aataatatta tatagtagtt ttatttcaaa
     8221 ataatttgac ttaggcatca tttcacacct caatatagcg cctaaaccct tgatattact
     8281 gactttttga aaaatatcat ttgattagaa atcattaaaa attctcaaaa agtccacaaa
     8341 aaaaaagccc cacaaaaggg caataaatga cgagttcagc aggcaagaaa ctagcacggt
     8401 caaacgtgct tttttattgc tgattgctga taggtatatt ataccatgaa gcgcgtagtt
     8461 tataagatta tgacctcaca aaagcccccc agattcgttt ctaagggctt ctagtttatc
     8521 tatggtgttt tagttgtcca gtacgaaaca aagcgaaata agggggcgaa tatgcagcct
     8581 cagcctactt atatgcttct agctctccgt tctggtggat tcttgcaaag tttaagacgg
     8641 atatctgttt gtatcggtgg tagctagtgg agctagtacc tgccatttct acgcattcgc
     8701 tcatagtttt ctttctcata tagcaataat ggataatgaa gtattttctg gctctctcgt
     8761 tctctatgct gttgatgtcg tgggcgaata tctccaaccc ctcacggatt gctttttcat
     8821 gctcaccgct caaatgccac tgatcaggta agacaagttt ccaagcctct tcatctatcc
     8881 taacttggtt ttcactacct gccatcctct gaaatctcag aaagtaagtc atccgctttc
     8941 tgacgttcat catcgtttta aacttatcca gctccatttt taacgacaac ctttctactc
     9001 ctgtaactta tgcctagctt aatcttcttc taggatttcc aaacttggca atcctttcat
     9061 ctcgttttct tttacgttct tcagcagact ctatacctat ctgttttcga cgctccacat
     9121 cttcttgatt gatattactc aagtaagctc ctaagacctt tgcgagtatt tcaccaattt
     9181 ctatagcata ttgattggcg tccagataat taactttatt cttttctagt aactcttcca
     9241 gaatctcact atcaagccta gcttttttca aattcgtcct taattttctg gagtagactc
     9301 ggaaacatat cttccaccat ctgcaccctc cttcactact ggagcaggct tgtctgaccc
     9361 cttaattcca gtcaagtcac ggatggtttc agcatccata tagccaggca ccgcttgatt
     9421 cagtttgata acaccatcac caatcaaggt cagcatgtta gcgtccgcct caaataaagg
     9481 ctcccacttc acgaccgttt tattgaactg tttcctcaaa taaggaaact catcacgtaa
     9541 acaagtagcg acataagcca cattcagcag accagaaccc agagagcgct gagccttccg
     9601 accagctaaa cgcaagttct catgactagc cttgatggct tcaacggatg acggattgtc
     9661 agaaacaaaa ccaagatcat ccaaggtcaa tcccatttcc ccagaaaatc cagctgctgc
     9721 agtccgtaac tgctcagtaa aaggagacat gctggacgtg gtgaattgtc ccacattcgg
     9781 cttttccccc tcatcatctt tcgtaaacgt cagcaagcta gatacagttg ctttccaagt
     9841 atcaatcgcc tcagcatctt gactcaatcc caacacatac ttctgaggga atgaatagaa
     9901 ctcagcagta acatctgacc gcataagcgt tcgtttagca tatctctgat agtacatccc
     9961 agccttagta attcgtgacc gaccaaacgg ccgaacagta tcaggcctat gaatgactgg
    10021 caccagcaaa ggaacacccg tcggattttc gattgcaaac ggcttaccat ctttcggata
    10081 gaaccaagtc acatcactag taaaataagc ctcaagcacg gcataaccat tgtcatccct
    10141 tttcaaaacg gcatagccct ctatcaacaa gccagtgata ggatccagaa caccagttgc
    10201 attactcgcc tcgataacct gcaaccgagg agcgtcatca tcgtcccctt gcgagatgta
    10261 aacaaaacaa cacgacccaa tcagagccga aagaatcgcg ctatcaaaga atacatctgg
    10321 attgttctga gcaaagattt cattcgctcc aaactcatca ttggcaaact cacgaaagac
    10381 caaacgatct gcaagactgt caacaccctt agcagtccaa cctaagaccg ctcgatattg
    10441 ttgcctgatt tgaggtggta tcgtaatacc aacatctatg tcattgtgtt gcatagcata
    10501 ctgattgtat ctagtatcta cacccatttt ataattggct agcttcttcc tgagatagcc
    10561 catacctttc aatgtcattt tatacaacta cctttcattt cccgcgagaa aaaatgtaca
    10621 gtgatggtgg gaagttcggg agctccgagg gggagggggg tatcccccct ccttctccct
    10681 tgcttctcca atctctttca caaaaaatat ttttccgatt cactttatta aaaaactttt
    10741 taattatttt tttatggagt ctttttatgt tctctttaaa ataaatcttt caacatttca
    10801 ctcatcgctt tgttcagttt tttctggtgt tcatttggca ttgataggcg ctgactaact
    10861 tctctatcaa cctctttgcg cttctcttcc atcaagcgtt caatctcttg ctggtgctct
    10921 ctttccttct tttcttttaa tagttcatcg gaacgatcta tgacagcttg ccacttggcg
    10981 tctcttgcta aacattcttg tctatgtcgc tccatcgcgt caactgcttg tttagttttc
    11041 tctttgtaaa tctcagctga cttttctgct aaatgcttcc cgtattcgtt taaatcaatc
    11101 ttaccagtag gtaggggcat tctatatacc tcatctttct att
//
LOCUS       DAVMBH010000059        11130 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVMBH010000059 DAVMBH010000000
VERSION     DAVMBH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.059"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            44..424
                     /locus_tag="VYP30_001828"
     CDS             44..424
                     /locus_tag="VYP30_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808773.1"
                     /translation="MKLKRLALISGIVGLVGGILLLIGPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            958..1650
                     /locus_tag="VYP30_001829"
     CDS             958..1650
                     /locus_tag="VYP30_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1808774.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1703..4114
                     /locus_tag="VYP30_001830"
     CDS             1703..4114
                     /locus_tag="VYP30_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1808775.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYGFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSEANKINLWARLGDGNRAHKLLAEQLKTSTLQNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4364..5065
                     /locus_tag="VYP30_001831"
     CDS             4364..5065
                     /locus_tag="VYP30_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808776.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNSDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5067..7775
                     /locus_tag="VYP30_001832"
     CDS             5067..7775
                     /locus_tag="VYP30_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1808777.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGMALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLAFVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     YKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLIAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7871..8362)
                     /gene="tpx"
                     /locus_tag="VYP30_001833"
     CDS             complement(7871..8362)
                     /gene="tpx"
                     /locus_tag="VYP30_001833"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1808778.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8485..9414)
                     /gene="psaA"
                     /locus_tag="VYP30_001834"
     CDS             complement(8485..9414)
                     /gene="psaA"
                     /locus_tag="VYP30_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1808779.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9446..10294)
                     /locus_tag="VYP30_001835"
     CDS             complement(9446..10294)
                     /locus_tag="VYP30_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1808780.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10291..11013)
                     /locus_tag="VYP30_001836"
     CDS             complement(10291..11013)
                     /locus_tag="VYP30_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1808781.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3274 a         2066 c         2535 g         3255 t
ORIGIN      
        1 tgatacaatt ttatttgaaa aaaataaaaa aggagatttt attataaaat taaaaagact
       61 tgctttaatt agtggtatcg tcggtcttgt gggaggaatt ttacttctta ttggtccttt
      121 tgtcttgttg ggaacagcgg taaacacagc tgctacaact cttaatggag gagctactgc
      181 aggggctttt tcaggtgtag ccttactctt gaatgccttg aagattgcaa atcttgttct
      241 tggtatcatt gctattgttt actataaagg agataagcgt gtaggtgcag ctccgtctgt
      301 actaatgatt gtttctggtg gagttagtct cattccattc ttaggatggg ttggggggat
      361 tcttgctatt atcggaggat ctctattcct tgcaacattg aagaaattca aatcagaaga
      421 ataaaaggta ttttagcatg aaaagaacaa aaagtttatc ggtataggag tagctctatt
      481 atctctttct cttctagttg catgtggaac ataaagttca aagaatactt caacaagtaa
      541 tgatgagaag acagtagcaa catccaatag ttcaaaagaa acaatcactt tcgatacatc
      601 ggttgtaaca gacgatgcga ttgaatcaat acgcacttat gcagattata tagatcttta
      661 taaaaatatt tttgatgatt attttactaa agctgaggaa ggtttcaaag gcacagctat
      721 ggaaaataat gactcgttta ctaaactaaa agagtcaact caaaaattat tcgatgcgca
      781 gaaaaaaagg ttaaataatg aagatagaat agaaacaacc aaaaacaatg tgattgccaa
      841 acattgtcaa acagtccttt cctttttggt tttgactagc ttttttgtga aaaattgtgt
      901 aaaatagaat agataaacga ggggaaacct cggaaaattt aaaggagaat ccatctaatg
      961 gtaaaattgg tttttgctcg ccacggtgag tctgaatgga acaaagctaa ccttttcact
     1021 ggttgggctg atgttgattt gtctgaaaaa ggtacacaac aagcgattga cgctggtaaa
     1081 ttgatcaaag aagctggtat caaatttgac caagcttaca cttcagtatt gaaacgtgct
     1141 atcaaaacaa ctaacttggc tcttgaagct tctgaccaat tgtgggttcc agttgaaaaa
     1201 tcatggcgct tgaacgaacg tcactatggt ggtttgactg gtaaaaataa agctgaagct
     1261 gctgaacaat ttggtgatga gcaagttcac atctggcgtc gttcatacga tgtattgcct
     1321 ccaaacatgg accgtgatga tgagcactca gctcacacag accgtcgtta cgcttcactt
     1381 gacgactcag ttatcccaga tgctgaaaac ttgaaagtga ctttggaacg tgctcttcca
     1441 ttctgggaag ataaaatcgc tccagctctt aaagatggta aaaacgtatt cgtaggagct
     1501 cacggtaact caatccgtgc ccttgtaaaa cacatcaaag gtttgtcaga tgacgagatc
     1561 atggacgtgg aaatccctaa cttcccacca ttggtattcg aattcgacga aaaattgaac
     1621 gtcgtttctg aatactacct tggaaaataa aaaattgtaa gtctagaatt gatttctagg
     1681 ctttttatgt tagtatggaa gtatgataag gaataaaaaa caagattatg tactggccta
     1741 caagcaacca gcttcaacca cttacatggg ttgggaagaa gaagctttac cgataggcaa
     1801 tggttcttta ggagcaaaag tatttggcct tataggggct gaacggattc aatttaatga
     1861 aaaaagtctc tggtctggag gtccacttcc tgatagttca gattatcagg gtggaaatct
     1921 tcaggatcag tatggttttt tagctgagat tcggcaggct ttggagaaga gagattacaa
     1981 tctggctaag gaactggctg agcagcacct aattgggcca aaaacgagtc aatatgggac
     2041 ctatctgtct tttggggata ttcacattga gttcagccag caaggtacga ctttgtctca
     2101 ggtgacggac tatcagagac agctgaatat tagtaaggca cttgcgacga cttcttatgt
     2161 ctataaggga acgcgatttg aacgtaaagc ttttgcgagt tttccagatg atctcttgat
     2221 tcaatgtttt actaaggaag ggttggaaac tctagatttt actatagaac tatccttgac
     2281 ctgtgatttg gcttctgatg gaaagtatga gcaggaaaaa tctgattaca aggagtgtaa
     2341 gttggatatt actgattctc atatcttgat gaagggaaga gttaaggata atgatctgcg
     2401 gtttgctagt tatctagctt gggaaacgga tggagatatt agagtttggt cagatagggt
     2461 tcagatatca ggagccagtt atgccaatct cttcttggcc gctaagacgg attttgccca
     2521 aaatcctgct agcaattatc gcaagaaact agatttagag caacaggtga tagacttggt
     2581 ggacacagct aaagaaaagg gctataccca attgaaatca aggcatatcg aggactacca
     2641 agccttattc cagcgtgttc aattggattt ggaagctgat gttgacgcat ccactacaga
     2701 tgatttgtta aaaaattata agccacaaga agggcaggct ttggaggagc tgttcttcca
     2761 gtatggacgg tatttattga ttagttcgtc cagagactgc ccagatgctc taccagctaa
     2821 cctacaggga gtctggaatg cggtcgacaa tcctccttgg aattcggact atcacttaaa
     2881 tgtcaatctg cagatgaatt attggccagc ctatgttacc aatctcctag agacggtctt
     2941 tccagtcatc aactatgtag atgatttgcg tgtctatggt cgtctagcgg ctgtaaagta
     3001 tgcaggaatc gtctctcaga aaggtgagga gaatggttgg ttggttcata ctcaagcgac
     3061 tccctttggt tggacggcac ctggttggga ttactattgg ggttggtcac cagctgccaa
     3121 tgcgtggatg atgcaaaccg tttatgaagc ctattcattt tatagggacc aagactatct
     3181 cagggagaaa atttatccca tgttgaggga aacggttcgt ttttggaatg cctttttaca
     3241 taaggatcag caggcgcagc gttgggtgtc ttctccgtct tattccccag aacatgggcc
     3301 gatttcgatt ggcaatacct atgaccaatc tctgatttgg cagttatttc atgattttat
     3361 tcaggctgct caggaattgg gactggatga ggacttgttg actgaggtta aggagaagtc
     3421 tgatttacta aatcctttgc aaatcactca atctggtcga atcagggagt ggtatgagga
     3481 ggaagagcag tattttcaaa atgagaaagt ggaggcccag catcggcacg cttcccatct
     3541 agtgggactc tatcctggca atctctttag ctacaaggga caagagtata ttgaagcggc
     3601 gcgtgctagc ctcaatgatc gtggagatgg cggcacaggc tggtccgagg ctaataagat
     3661 caatctctgg gcgcgtttgg gagatggcaa tcgagcccat aaattattgg cagagcagtt
     3721 aaagacatcc accttgcaaa atctttggtg tagccatcct ccttttcaga tagatggtaa
     3781 ttttggtgct actagtggca tggcagaaat gttactccag tctcatgcag cttatctggt
     3841 acctctagct gccctacctg atgcttggtc aacaggttct gtttcaggct taatggcacg
     3901 tggacatttt gaagtgagca tgagctggga agataaaaaa ctcttacagt tgaccatttt
     3961 atcaaggagt ggaggagatt tgcgagtttc ttatccagat attgagaaga gtgtgattaa
     4021 aatgaatcaa gaaaaaataa aagcgaaatg catggggaaa gattgtattt cggtggcaac
     4081 agcagaaggt gatcttgttc aattttattt ttaagaagat gttataaggc agtaatttga
     4141 aactgccttt taataaggat ttaagaatat aggcagtttc caactagttg aaaaagcgtt
     4201 ataatgataa taggaagtaa tactcaatga aaatcaaaga gcacaaacaa ggaagctagc
     4261 cgcaggttgc tcaaaacagt gttttgaggt tgcagatgga agctgacgtg gtttgaagag
     4321 agattttcga ggagtataat ttgtttgata gagggtgggt ctgatggctt atattgagat
     4381 gaaacactgt tacaagcgtt atcaggttgg ggacacggag attgtggcca atcgtgatgt
     4441 gaattttgag attgaaaagg gggaactggt tattatcctt ggtgcttcag gtgcaggcaa
     4501 gtcaacagtt cttaaccttc ttgggggaat ggataccaat gatgaagggg aaatctggat
     4561 tgatggtgtt aatattgcgg attatagttc ccaccagcgc accaattacc gtagaaatga
     4621 tgtggggttt gtttttcagt tttataatct agtttctaat ctgacagcta aggaaaatgt
     4681 ggaactggct tctgaaattg tgacagatgc cttgaattct gatcaggtct tgacagatgt
     4741 aggtctggct catcgtctaa ataactttcc agcccagctt tctggagggg agcaacagcg
     4801 agtctccatt gcacgcgcgg tagccaaaaa tcctaaaatt cttctttgtg atgaacctac
     4861 tggagccttg gattatcaga cgggcaagca ggttttgaaa attctccaag acatgtctcg
     4921 tcaaaaggga gcgacggtga tcatcgtgac tcataatgga gctttggcgc ccattgctga
     4981 tcgcgtgatt catatgcacg atgccagtgt caaggatgtg gtgctcaacc agcatcctca
     5041 ggatattgac agtttggagt actagtatga tcaagcgaaa aacttattgg aaggacttaa
     5101 ttcagtcctt cacaggctcc aaggggcgtt ttttatccat cttgatcctg atgatgttgg
     5161 gatctctagc cttagtaggc ctcaaagtaa ccagtcccaa catggaggcg acagctaatg
     5221 cttatttaac aactgctcaa accttggatt tggcagtcat gtctaactat ggcttggatc
     5281 aagcagacca agaagaacta aaacagacgg agggcgcaga ggtcgagttt ggctatttga
     5341 cagatgtgac tatggataat gggcaggatg ccattcgact gtactccaaa ccagagcgaa
     5401 tttcaacctt tcagctaaga aagggacgac ttcctcagtc agacaaggaa atcgctttgg
     5461 ccactcattt gcaaggccaa tacagcgtgg gacaggagat tagttttaaa gaaaaagaag
     5521 agggtcattc ctctttaaaa gaccatactt ataccattac tggttttgtg gattcggctg
     5581 aaatcctctc ccagcgagat atgggctacg caggaagtgg aagtgggact ctgacagcct
     5641 atggggtgat tttacctagt cagtttgatc agaaagtcta caatatagct cgtttgaaat
     5701 atcaagattt agcaggttta aatgcctttt catcagctta tgaagaaaaa tccaagcaac
     5761 atcaggaaga ccttgaacaa actttatcag ataatggcaa ggtacgtctg caacttttga
     5821 aaaaagaagg acaagagtct ctagacaagg ggcaagagac ccttgacaag gctcagacta
     5881 atttgcagga aggcaagcgt cgtttagcag ctgctcaagc tcgtatacag gctcaagaaa
     5941 gtcaactagc cttgtttcct caagttcaga gagagcaggc tagtgctcaa cttacccaag
     6001 ccaagcagga attgggcaag gaagaggata aactaaagca agctgaacaa aatctagccc
     6061 aagaaaagga aaaattagaa aaacatcagc aagtcttgga cgatttggcg gagccaaggt
     6121 atcaggtcta taatcgtcag accatgccag gtggtcaggg ctatcttatg tatagcaatg
     6181 cttcatccag tattcgagca gtgggcaata tctttcctgt ggtactttat gccgtagcag
     6241 ccatggtgac ctttacgacc atgactcgct ttgtagacga agagcgaact catgcaggga
     6301 tttttaaggc cttgggttat cgtagtaagg atattatcgc caagtttctc ctttatggac
     6361 tagtagctgg gactgtcgga atggctctag gtagtatact tggtcattat ttgctagcca
     6421 gtgtaatttc aagtgtcatt acaaaaggca tggtggtggg agaaactcag attcagttct
     6481 attggaccta tagcttacta gcttttgtct tgagcttgtt ggcgagtgtg ttaccagcct
     6541 atctggtggc ttggagggaa cttcatgacg aagcagccca gcttctactt cctaaacctc
     6601 ctgtcaaagg agctaaaatc ttattggagc gtatcggttt tatctggcgt cgtctcagtt
     6661 ttactcataa ggtaacagcc cgcaacatct ttcgttataa gcagagaatg ttgatgacaa
     6721 tctttggtgt ggcaggttct gtagctctgc tctttgcagg tttgggaatc caatcttctg
     6781 tagcaggagt tccgtctaaa cagtttcaac aaatccaaca gtatcagatg cttgtctctg
     6841 aaaatcctag tgcgaccaat caggacaagg tagagctagc agaagtgttg aaagggcagg
     6901 agatactagc ctaccagaaa atctattcta aagcgctata caaggatttc aaaggcaaag
     6961 ctggtcttca aaacattact cttatgatga tagagaagga agatttgact ccctttatcc
     7021 atcttcaaca tcatcagcag gagctgacat taaaagatgg catcgttatt acagctaaac
     7081 tcgcccagct ggcaggtgtc aaggttgggc agactttaga aattgaaggt aaggaactaa
     7141 aggtcgctgc tattactgag aactacgttg gtcactttat ttatatgagt caggctagct
     7201 atgagcaact ttacggacag ctaccccaag ccaacactta tctggtctca ttaagggata
     7261 ccagtgcaac tagtatcgaa agtcaggcgg gcttgcttat gaatcaatct gcggtgtcca
     7321 gcgttgtcca aaatgcttca gccattcgac tcttcgactc tatcgctagc tcactcaatc
     7381 agaccatgac catcttggtc atcgtatcgg ttctattagc tattgtcatc ctttacaatc
     7441 tgaccaatat caacgtagct gagagaatcc gtgaactctc cactatcaag gttcttggtt
     7501 ttcataataa tgaagtcacc ctctacattt accgtgagac gattgtgctg tcccttgtgg
     7561 gaatcgtact tggtctgata gctggtttct atttacacca atttttgatt caaatgattt
     7621 cgcctgcgac tattctcttt tatccgcagg taggctggga agtctatgta atcccagtgg
     7681 cagcagtaag catcattttg accttgcttg gtttcttcgt caattattat ctgagaaagg
     7741 ttgatatgtt agaagccctg aaatctgtag agtaaggtag ttatttttag ctgattgaac
     7801 ttctatttac taatattcaa aaatcctccg tttcaaagag cagggaactc tttgtgacag
     7861 aggatttttt ctatagggct ttagcagctg caattgcggc ttcgaagttt ggctcagaat
     7921 tgatattatc cacgtattca acgtagcgaa tcgtattgtc agtatcgagg acaaagactg
     7981 cgcgtgctaa taggtgccat tcgttgatca agagggcata atcgcgcccg aaagaatggt
     8041 caaagtagtc tgaaagcata atggcattgt caaggccttc agcaccgcac caacgttttt
     8101 gagcaaaagg taggtccatt gaaacagtca atacgaccgt gttgtccagt ccagccaatt
     8161 cttcattaaa acgacgtgtt tgagttgagc agatgcctgt atcgatagaa ggaacgacac
     8221 tcaagacttt tttcttgcca tcaaaatcag ccagagattt tttagaaaga tctgttgtag
     8281 taagagaaaa atcaagcgcc ttgtcgccga cttgtagttg tttacctgta aagctcacag
     8341 gatttccgag aaaagttacc ataggatact ccaatctttt ttcttccatt gtatctgaaa
     8401 cagtcagaat tttccaatga tttgaccgga aatgtgggca tagaaaaaac gccagctcac
     8461 atgagaatga cgtttttcag aggcttattt tgccaatcct tcagcaatct tgtcaaggtt
     8521 gtatttcatc atgctgtagt agctgtcgcc ttctttacct tgttctgcga tagagtcagt
     8581 aaagatttgt gcgtagattg ggatgtttgt gtcttgagaa acagttttca ttggacggtc
     8641 atccacactt gattctacaa agagtgatgg aacttttgtt tggcgaagtt tttcaaccaa
     8701 ggtcttgatt tgttcaggag ttccttcttc ttcagtattg atttcccaga tgtaggcact
     8761 tgggacacca taggctttag agaagtattt gaatgctcct tcgctggtta caatgagttt
     8821 cttttcagca gggatcttat taaatttatc cttactttct ttatcaagtt tgtctaactt
     8881 atcagtatat tctttgagat ttttttcata gaattcttta ttgttagggt ctttggcgct
     8941 caattgtttg gcgatatttt tagcaaaaat aataccgttt tcaaggttaa gccaagcgtg
     9001 tgggtcttct tttccttttt cattttgacc ttcaaggtag ataacatcaa cgccgtcgct
     9061 gactgcgaag tagtctttgt tttcagtttt cttggcattt tctaccaatt ttgtaaacca
     9121 agcattgcca cctgtttcaa ggttgatacc gttatagaaa atcaaatcag cctcagaagt
     9181 tttcttaacg tcttcaggaa gtggttcgta ttcgtgtggg tcttgcccaa tcggaacgat
     9241 actatgaagg tcaattttgt caccagcaat atttttagta atatcagcga tgattgagtt
     9301 tgtagcaaca acttttagtt tttgaccaga agttgtatct ttttttccgc tagcacatgc
     9361 tacaagaatg attgcagaaa gaaagagaac gagtaatgta cctaattttt tcattagatc
     9421 ctccaattta ttagggcttt gccccttatt ttaacaaatg tttatttttc agtttcaaat
     9481 atcgttgttt gggagcgata aagaagctaa tgagaaagaa actagcagct gtaagcacga
     9541 tactagaacc tgccgcaaca ttaaaactat agccaataaa gagtcccaaa actgaagcag
     9601 tagctccgaa ggttgaggaa aggaaaatca tgcttttcag actattagca tacagataag
     9661 cagttgcagc tggggtaatc agcatggcta caatcaggat agttccgaca ctttgcatgg
     9721 ctgtcacaga cacgagagtc aggagtacca tgagaaggta gtgatagaaa ttgacaggca
     9781 ttcccatggc tttagccaag agttcatcaa aggaagttat caagagttgc ttgaagaaaa
     9841 tccaaattaa caagaggatg gctgccccca cacccatagt aataaacata tccgtatctt
     9901 ggacggccag aatattacca aaaaggatat ggaaaaggtc agttgaactt ttagcgacac
     9961 caatcaagat gataccgagg gctaagaaag aagaaaaggt aatgccgatg gcggtatcgc
    10021 ttttgataat cgagtttcct ttgatgtagg taatgatgat ggcagctagc aatccaaaga
    10081 caatggctcc gataaagaag tcaaggccca agatgaagga gagggctaca cctggtaaga
    10141 cagcatgtga aatggcatct cccatgagtg acatcccgcg tagaataatg aaacatccca
    10201 cagctccagc tacaatcccg acgacaatag ctgttatcaa ggcattttgt aggaaatgga
    10261 atttttgcaa tccatcgata aattctgcaa tcataggtca cctccattga aaaagagttg
    10321 attaccgtaa gcttctttta gattggtttc ggtaaaagtt tcttttgttg gaccaaaggc
    10381 aatcacttct cgattgacaa gtaagacttg atcgaagtag tggggaatct tgctgaggtc
    10441 gtggtgaacg atgagaaccg tcttcccagc ttttttcaaa tctctcagcg tattcatgat
    10501 gatttcctca ctgacagagt caatcccagc aaagggttca tccaagagga tatagtcggc
    10561 ttcctgcacc aaacatctgg caatcaagac ccgctggaat tgacctccag acagttgact
    10621 aatttgacgt tcagcgtagt cagctaggcc gacgatttca agggcctctt gcactttctt
    10681 ccaatgttta gcctttaaac ttcgaaagag aggaatagag ggaaatagtc ctaacgagac
    10741 gcattccttg accttgatgg gaaagttgta gtcgatattg attttttgtt cgacataggc
    10801 aattcggtgt aaggattttt taacttcctt gtcatcgaga aatgcctgac cttgatgtgg
    10861 gataattccc agcatacctt ttaatagtgt tgatttccca gcgccgtttg gaccaatgat
    10921 gccggtaatt gttggtccat ggagcactag tgaaatatcc ttaagtgcca acgtttcttt
    10981 gtaggagaca ctgaggtttt cgatacgtat cataaacttg tattcctcct gtctcttaat
    11041 atacattaaa aaaaaaatta agtcaagtta atttttgaaa aaattaaaat aataactgaa
    11101 aaatagattc taaagataac tttcaggata
//
LOCUS       DAVMBH010000060        10978 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVMBH010000060 DAVMBH010000000
VERSION     DAVMBH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10978
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.060"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1..933
                     /locus_tag="VYP30_001837"
                     /pseudo
     CDS             1..933
                     /locus_tag="VYP30_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1061..2083)
                     /gene="cbpF"
                     /locus_tag="VYP30_001838"
     CDS             complement(1061..2083)
                     /gene="cbpF"
                     /locus_tag="VYP30_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1808782.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDSPLTYDEEKLKAAPWYYLDPTTGI
                     MQTGWQFLGNRWYYLHSSGAMATGWYQDGSTWYYLDAETGDMRTGWQYLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYTYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2102..2923)
                     /gene="cbpG"
                     /locus_tag="VYP30_001839"
     CDS             complement(2102..2923)
                     /gene="cbpG"
                     /locus_tag="VYP30_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1808783.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVCYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGYSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3004..3243)
                     /locus_tag="VYP30_001840"
     CDS             complement(3004..3243)
                     /locus_tag="VYP30_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808784.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3393..3659)
                     /locus_tag="VYP30_001841"
                     /pseudo
     CDS             complement(3393..3659)
                     /locus_tag="VYP30_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3684..3995)
                     /locus_tag="VYP30_001842"
     CDS             complement(3684..3995)
                     /locus_tag="VYP30_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1808785.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(3920..4162)
                     /locus_tag="VYP30_001843"
     CDS             complement(3920..4162)
                     /locus_tag="VYP30_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1808786.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(4163..4795)
                     /locus_tag="VYP30_001844"
     CDS             complement(4163..4795)
                     /locus_tag="VYP30_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808787.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(4809..5804)
                     /locus_tag="VYP30_001845"
     CDS             complement(4809..5804)
                     /locus_tag="VYP30_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1808788.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(5801..6499)
                     /locus_tag="VYP30_001846"
     CDS             complement(5801..6499)
                     /locus_tag="VYP30_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1808789.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6577..7587)
                     /locus_tag="VYP30_001847"
     CDS             complement(6577..7587)
                     /locus_tag="VYP30_001847"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1808790.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SSQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7571..8578)
                     /locus_tag="VYP30_001848"
     CDS             complement(7571..8578)
                     /locus_tag="VYP30_001848"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1808791.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8565..9518)
                     /gene="mvaD"
                     /locus_tag="VYP30_001849"
     CDS             complement(8565..9518)
                     /gene="mvaD"
                     /locus_tag="VYP30_001849"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1808792.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            complement(9500..10378)
                     /gene="mvk"
                     /locus_tag="VYP30_001850"
     CDS             complement(9500..10378)
                     /gene="mvk"
                     /locus_tag="VYP30_001850"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1808793.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10500..10679)
                     /locus_tag="VYP30_001851"
     CDS             complement(10500..10679)
                     /locus_tag="VYP30_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1808794.1"
                     /translation="MLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNT
                     TVDGYFVNYNGEWVQ"
BASE COUNT         3266 a         2523 c         1948 g         3241 t
ORIGIN      
        1 gtacctgaga gcggagaatg ccatcctaaa aaagttaaga gaactccgat tgaaggagga
       61 aaaagagaaa gaagaaagac agaaattgtt caagaattaa tgactgagtt ttcgttagat
      121 cttcttctaa aagccattaa actagctcgt tcgacctact actatcactt gaaacagcta
      181 gataaaccag ataaggacca agagcttaaa gctgaaattc aatccatttt tatcgaacac
      241 aagggaaatt atgcttatcg tcgaattcat ttagaactaa gaaatcgtgg ttatctggta
      301 aatcataaaa gagttcaagg cttgatgaaa gtactcaatt tacaagctaa aacgcgacag
      361 aaacgaaaat attcttctca taaaggagac gttggcaaga aggcagagaa tctcattcaa
      421 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      481 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      541 attatcgcct ataatctttc aacttcaccc aacttagaac aagtacaaac aatgttggaa
      601 caggcattca cagagaagca ctacgagaat acgattctcc atagtgacca aggctggcaa
      661 tatcaacacg attcttatca tcgattccta gagagtaagg gaattcaagc atctatgtca
      721 cgcaagggaa acagccaaga caacggtatg atggaatcct tctttgggat tctgaaatcg
      781 gaaatgtttt acggttatga gaagtcgttt cagtcgttta agcaattgga acaagctatt
      841 atagactata ttgattacta caacaataaa cgaattaagg taaaactaaa aggacttagt
      901 cctgtgcagt acagaactaa atcctttgaa taaattattt gtctaacttt ttggggtcag
      961 tacattgtta acttgatact atgcgttttt tgattgtgaa gacttttatc cacctattat
     1021 acaaagtcaa gtatccatca cagtttacaa ttagtcttca ttacttaacc cattcaccat
     1081 tatagtttaa atagtaacca cctactgtgg tattaacagc taaagcacct gaatcatagg
     1141 tatagtacca gttaccattg acttggaacc agcctgtttt catatctcca ttacttgcat
     1201 ttagatagta ccaagtcgaa ccttcctgat accaaccagt tgccatagct cctgatgaac
     1261 ggagatagta ccacttgtta ccaaggtatt gccagccagt tctcatatca ccagtttcag
     1321 catctaaata gtaccaagtt gaaccatctt gataccagcc agttgccata gctcctgacg
     1381 aatggaggta gtaccatcta ttacctagaa attgccaacc agtttgcata atgccagttg
     1441 ttggatctag atagtaccat ggagctgctt ttagcttctc ttcatcatac gtaagagggg
     1501 aatccttaac ccaaccacgt gctagctctc caaccgtcaa tctgttgatg cgcgaatcaa
     1561 agccaccatc cttctgtaaa taataccaat gaccctcttc gtaaatccaa ccagttttta
     1621 aagtatgata actacgctga tcttcaaaat aatagactcg tttctctgct gggctatcat
     1681 attcttcccc atgatgtttg ttggtattcg tagcagtttt tgcttctaaa acttgcttgc
     1741 caacaaattc ttgtaagaca ccatcttgac caaaataaaa ccaatctggt ctaagagcaa
     1801 tctctattct tggagaagga ccaatcgtaa cccccttgtg tggagcaggt atatattgcc
     1861 agccgacaac catctctccg gataaaggat caaaataata gtacttccca tctatcactc
     1921 tccagtaggt ttcttttaga tccccctttt tgtagtaggt tctaccattt tcttggacaa
     1981 actgccatcc ttcagaatca tctgcaaata ctgtactggt ccctagcaaa ccgaagaaaa
     2041 atgtggctag tgcgacttgc atcatttttt tcaaaagctt cattttatat atcctccaac
     2101 attaaatcca ctcaccagat gaagcgaagt tataaacttt accatcgata gtttggctac
     2161 ctgtaaccat tgctccattt gaattgagat aataccattt tccatttact ttttgccaat
     2221 ctgtaagcat cttaccggaa ctgtctaaat aataccaagt atcatttatc tcctgccaac
     2281 ccgtttgttt atcatgttgt ctataatggt accaactacc atttattttc ttccatcctt
     2341 caagagagta acctttaaga accgaataaa taaatggcaa atttcgttca tttaatttaa
     2401 ctgcactgtt aatttgatta gctccatctc ctaaagtatg cactcctact acacggtgac
     2461 tagcatcata aactgtagat ccactatacc cctctaaagt atcaacttgg taatccaaga
     2521 acatgccatc atcacttaaa acttgttttt tatctgtata catttgatga attttaaaat
     2581 tatatgatgg atagcctgtg atagtcacag ttattcctgt caaatttttt tgactagtag
     2641 gaagacccaa agtccctaat tttgcaccaa tgggctcttc tagaattaat aaagccaagt
     2701 catattccct tgcatcctta gaatttaaat ttctaaattc cttcaaataa caaacttcct
     2761 ttactttgat ctttccaaat agttcttgac ttggactaac agccggaaga acataaatat
     2821 catccgcttc tttcccatag tcatgtctgt agtagttgtg agccgctgta attaacacat
     2881 tatctttaat aaaattcgca cttcccctcc cttctacatt cattccatcg gctactccat
     2941 aatacttaga taaaaccata gctgaagtcg aatacggata ctgtaaagta ttatcaattt
     3001 taatcaaatc atcattaccg ataatacttc tgattgcttt tggtagtatg aaccatacgt
     3061 tggtgaaatc tcagataatg aagaatcatt agactctgga cctttttcta gtgtctcact
     3121 tacctcatat tcttcacctg tactagaaat aacactcaaa gcagatactg tcgataactg
     3181 gctagccaat aaagtactcg caataattga aatacccaat tttttataaa cagttttctt
     3241 cattatcgta tcctcctaat gtaattatag cgtactattc taaatttctc aatctactat
     3301 agaatcaaga aatctaccac cttctttaaa taccctccat tatcacataa acaggtaaac
     3361 ttttcaatta atgactgcgc ttttcaatca cgctagaggt acttgcttgc ttctttgata
     3421 ctaagttcag ccattctttc cttgtttttc tcaataaagc atgttaccca agtgggattc
     3481 gttttggagt agtctcgcag agtccagcca atggctttat tgataaaaaa ttctgtttgg
     3541 ttcaagttat gaaggagaat cttttccatt aattgagtat tggtcttctc ttttcttaac
     3601 aactggtggt caatagcgac acgtctcagc cagatattat ctgataggct ccattttata
     3661 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca gattgctcaa aacactgttt
     3721 tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat taagattatt
     3781 tcttctagtt cagggtgttc atacaccaaa ctccctacta ctcgatctag gatatctacc
     3841 gtgtcccaca aggattttgt cacgactaac tgctctagct taggcaaatc ggtttccttt
     3901 agataagact gcattgcttt caaatagtta gcagccacat attggtattt tctaggatcc
     3961 ttttcccagc aagtgtctgc aaaatcccaa tcgataatct ttgttttttt cgcttctgga
     4021 aaatattttt atagagttta tttctttcag gcaccgcaat acctagaaaa gaaaattgat
     4081 ggcgcatata ggcttccatg gaccttgctt ttttagagtc ttttgctgct tctagctcct
     4141 caagtaaatc tgctaaactc atctaaaact cctcttgccc caccaaatgg tgctgaaagg
     4201 catagacagc cgcctgggta cgatcgctga cttcaagttt ggcaagaata ttggacacgt
     4261 gggtcttgac cgtcttgaga gagataaaga ggtcatctgc gatgcgctga ttttcgtagc
     4321 ccttggcgat gagttggaga acatctcgct cacgcgcagt caattcttca tgaagttcca
     4381 tatgattgcg gtggtattca accttcttgc taacctcttg ctcaatggcc agctcgccag
     4441 cagctacctt actgacggca tgaagcaatt catctgcact agaagtcttg agcatatagc
     4501 ctttggcacc agcatctaag actggcatga ttttttcatt gtccaaataa gaggtcacaa
     4561 tcaaaatctt ggcttcaggc cattctttaa ggattgctaa ggtcgcgtca attccattca
     4621 tctcaggcat gacaatatcc atgacaatga catctggacg cagttccaag gccaagtcaa
     4681 tcccttgaga cccgttggac gcctcaccca caacttctac atcgtcttgg aggtcaaagt
     4741 agcttttcaa acccaaacgg accatttcat ggtcatctac tagtaaaatt ttcatcttta
     4801 ctcctttatc attccttatc taacagggga atacggatat caactgccag cccttgcttg
     4861 ggagctgtta ataactgaac cgtccctgcc atatcttcaa cccgctcctt gatatttcgc
     4921 agtccataac tcaagtcgtc taagctccct aactggaaac caatcccatt gtccaccacc
     4981 ttcagttgca attcaacatc tgtctgatag aggtagacat ctaggcaaga tgcctgggca
     5041 tggcggaggg tattgctaat caactcttgc aggatacgga agatatgctc ctcgattttc
     5101 ttaggcaatt tcgtcatatt ctgcttgaga ctaaccctaa gatcactctt gtcctcaagc
     5161 tcttttaaga gaatctgaat cccttctatc aagctcttct gctccagttc aactggtcgc
     5221 aaatgcaaga gcaaaacccg caaatccttc tgggcagttt ctaaaatagc tgtgacactc
     5281 tgcaactgga tctgcatctt ttctctatcc aatttcaaag cctgctgact gatacccgat
     5341 aaaatcatgt gggccgcaaa caactcctga ctgactgtat cgtgcaaatc ccgagcaatt
     5401 cgcttccgtt ccttctcgat gatttcctct tcctgagcaa ggctctgatt ttcagctttt
     5461 tgaagagcct ctgtcaaaag gttaagttta cctgataagg acttgaaact ggcatccaaa
     5521 tctggatctg caacctgaac cacttcttgc cctgctaata aacgcttgag attagcctgc
     5581 atttttctta gagaaagctc ttcgatccct cgccaaaaca gggctaagag acaggtcatg
     5641 gacatgctga aaaccaacaa taaaaagaca aatttttctg ttttttcgac atcgtacaaa
     5701 aagatagacc agtcaaaatc aagtatttcc agcaagctgt gggagaaaaa aaagacaaat
     5761 aggaaggagg tgagagcaat aatgacatag gcttgttttt tcatcctcta accacctcca
     5821 catcaccaat catagtggtc aagaaaatct tgacactctt gttactcttg agatagtctt
     5881 ttgtttcttg atgatagtgt tcattgcgga gggctcgctt gggctggttg aaaaaagtca
     5941 aatccccata gagacagtta acgctgagac tgacttccac atctacaggt acgatgattt
     6001 tggtcgttcc taccatcttt ctgaggataa tgacattgtc atgattggtt aagatgaccc
     6061 tctccagatg aatagtgtcc ttgcccatga agcgaaagag attgatatca tcgaattggc
     6121 aagtctggta gcttgaaaaa tgatgaagat ttccaaacca acgatttttc tccttcttaa
     6181 ccgtcacgac ctcttcaaaa accaaattgg tctgctcttt ttcctggttc atcatcgggt
     6241 aaagaagaaa gaggctatag ataaccgcaa caaaaatagc tagaatcaca aaaggattga
     6301 gcataacgat gaaaaagaag agaatggtta ccgctactaa aagaagatta tttccctctt
     6361 taccagtgta gtagcgaatc aaaagcaaaa agaggaatag tatcagcaga aaacgcgaaa
     6421 aatgctctga taccatcaaa atcagagctc ctgtcagaag acaggcttcg ataaataaaa
     6481 agattttaaa ttttctcata ggttcatcct ctcccttcta ttttatcaca attcaaaaaa
     6541 gtcacctcag tctgaggatg gaaaaaaagg cgctggttac gcctttttca tctgatcatt
     6601 tgcttctttt aattttccat aaagaagata gtctactttt tgtagatctg ctatggtggc
     6661 acagttaagg gaacacataa tcaagcgtag atctgctttc cagccttgga caatgccaat
     6721 cacttcttca actgtgtagg tttcaaccaa ttccagaacg gttcgtgaca atcccacagc
     6781 cttagcacca aaaaccaagc acttaatcat atccagcgga ttccgaaccc ctccactaac
     6841 caagagttcg accttatctt tccattcttg ggcattgaga agggcctgca tggtagactg
     6901 accccattga ttgaggtaat cacgctggct actacgacgg ttttcgatat aggcaaagct
     6961 ggtgccacca cgacccgata ggtccactgt acgaacaccg aattcatagg ctctttcgat
     7021 tgtcttggca tccattccaa agcccacttc cttgaggaca ataggaacgg gaatttgctt
     7081 gctataatct gctagatgcg attgccagct tctaaacttc ctttctccct cgggcatgag
     7141 taattcctgc atgacattga catgcacttg caatagcaca ggattcatct cttctacagt
     7201 ctgaagtcct aactcgacag gcttgtccaa tccaatattg gttccaagga ggagattggg
     7261 atgactagac ttgacagaaa aagaatcatc cgttggattt ttgagggctg cgctataaga
     7321 acccgttaca aataaaatac cacaggattc cgccacctga gccagctttt gattgatttc
     7381 tcttccctta ttacttccac cagtcatggc attgatataa aaaggaaagt cccactttcg
     7441 accagcaaac tctgtcgaaa gatcgatttc atccagattg taaagaggca aggaagaatg
     7501 aatcagctcc acctcatcaa agctattata ggaacttttc tgctcaaggg catagaggat
     7561 atgctcgtcc ttacgatttg tcgtcatgtc ctatcctttc ttgatataag agctcaatcc
     7621 ccagatcggc ccaacgattt tttaaggttt tggttgattg cgcatcaaaa ctcagggcga
     7681 tgccacagtc accaccacca gcaccactac tcttggcaac ggcctgcaaa tcttgactgg
     7741 cttctttcaa ctgtctaagc aaaggcgtgt aaatatctgt actcaagcct tctaaaagct
     7801 tgctggctac ttctacttgc tcgataactt tttcggcttt cccctgctcc aaggcttcga
     7861 ccaaagaaac caccgtttct tttgaggaac ttaaaaaatt ttgattgata ttttgcttga
     7921 tttgctggac catgtgactc gatacagcca cttccttggt ccatcccact aagaaatcac
     7981 attctaaagt tggtttcact tgtgagataa aaaatcccca atcacgctcc agaactgtcg
     8041 ccaagttttc ttcttctaac caagcagccg ccttctggcg atcaaatgac tggtagagaa
     8101 ccaaatcctc tgccacaata caggcaaggt cgcccatgga accattgtct cctcgcttga
     8161 gcaagacagc gctagtcagc ttgaacaaga gattctgatc aaccgaaaga ttatagagag
     8221 ccaataaagc cttgacaacc aagacaacga cgctgccact agaacctaga ccaaactttt
     8281 tcccttctcg ttccattttg ccacagattt ttagggaaaa aggtcttaaa ttctgaccgc
     8341 gaacagcgag gaagtctccc atcaaagcaa tcgtttcttg aatcaagctg tagtcaggat
     8401 taggccttaa gtccactgcg aaatcaaaca tatctgaata gatacggtag ctgtcagaaa
     8461 aagcaatctc agccctcata tagatgggaa tatcctttat caaagctaac tgccctggct
     8521 ctaaaatagc atattcacct gcccaataga gttttccgca agttttaaca gcaatcatct
     8581 tgactcaaat cctttgtttt tgacacaatc aagcgataac gatgaccgaa aatttctgat
     8641 aaatgctcca agtctttctc ctgacagaag accttaacat tgggaccagc atccatggta
     8701 aagtagcagg cctctccttt ctcacgaagc tggcgaacaa agtccatagc ctcataagag
     8761 gcatccgtca gataagaaaa ggctggacta gcagtctttg tcgtagcatg catagccagg
     8821 gcatttttct ccgttaattc tccaatcttg gcaaaatcat tttccttgag ataaatcagc
     8881 atatcctgat agtccttctc agactgacga acccagtcgt caaaagtcgt cgaggtttcc
     8941 acacaaagtt tcatcccgtc acggctagag attggttttt tcttgtcctc tagcaccaac
     9001 ataatcatag ctagtttcaa gtctgtctct acagggtaaa tttctccact atccttatcc
     9061 caggctccta gtggtccata aaaactccga gaagaagaac ctgaggcaaa tttggcttcc
     9121 tgtgccaact gacttctatc caatccaagc ttgaaataag cattacaagc cttgaccagg
     9181 gcggacaaac cactagaact tgaggacagg cccgctgccg taggcatatt gttttgagta
     9241 tcgatacgga caaagccctc accagctgga cgataacggt caataatctt actcatcttg
     9301 gcatgctcga cctcattttg tagctgacca ttgatgtaaa attcgtcagc tgttacattg
     9361 gctggtaaag gcgacaaggt cgtctctgta tacatatttt ccaaagttag agaaatactg
     9421 ctagtagcag gcaccatctc tttttctttt ttctttcccc aatatttgat aatagcaata
     9481 tttgcgtagg aacgtactgt tacaggctct ctatccatgt ctgaacagct cctttctctt
     9541 ctaatctttc tgctagttct tgtgcgtgtg tcaaattggt taccaaggct atgatacaac
     9601 ctcctagccc accaccgctc atcttggcac ccagagcacc atggctaaga gtcgtttcaa
     9661 ccaaaaagtc tgcctcaggg ctactgactc caatttcttt taaatgtaaa tgcgcttgac
     9721 tgaggatttg tcccagtcct tcagcatctt tttgtgaaat cgcaacttct gcttgctggg
     9781 ttaattctcc caaggcatgc aaaaacggta gggcatcctt gcccttattt tgaaccactt
     9841 ggatggcttc acgagtatga ccataaacac ccgtatcggc aatcaccaaa taggcggata
     9901 aatccatctc aagttctgta aatcctacgt tcttgataaa gcgaataggt tggtcactaa
     9961 gacaggtctt agcatccaaa ccactaggat tcatatgggc aatcatttca gctcgattga
    10021 ccaagatttc tagtacatca tgaggcagat cagcctgata gtagtcaaat actgcacgaa
    10081 tggccgctat gctgatagcc gctgacgaac ccatcccccg tttctcaggg atagccgagt
    10141 caatctcaca acgaatgcag gcttctgtga tattcaaata ctccagtgag gcataaaccg
    10201 ccatggacaa ggtatcctcc tcataaaggc gccaaggact ctctgcagga actaccttac
    10261 aggtcacctc cacctccaaa agaggcaggg aaatggcagg ataaccgtaa acgaccgcat
    10321 gttcccctat taaaattatc ttactatgtg cctgaccgac accaactttt tttgtcattt
    10381 tttcctttta ctagacgaaa aaacgtctta tttttcatac aagtattaat tctttcctat
    10441 ctattttatt atattttcac aaaaaaagcg attgtttcca ttcacaatcg cttctttcat
    10501 tattgaaccc attcgccatt ataattgaca aaatagccat ctacggtcgt attcactgcc
    10561 aaggcacctg agctataagc gtagtaccat ctgccattga cctggaacca acctgtcgtc
    10621 atagaacgac gaaagaaact ccataccatt aagtaaagag gaaagtcgtg agggagcatg
    10681 cgccattgac aacctgtttt agtgacgtac aaagtctcat taacaagtac tcgtttcggt
    10741 catttatagg tgcggtgttt ggagaaatag ggttcaatct tagcccattc ttgatcgttt
    10801 aaatcagtat catatacttt gcgtgtcata actctagttt aacatttttt gtgaatacag
    10861 gttctaaata atcgaccacg aaaatttctt aagtggaaaa cgccttatga agtatgctac
    10921 gggaaagtta tgcacttaat ttgacaattc aagatgtaaa aatatatact atagtaga
//
LOCUS       DAVMBH010000061        10827 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVMBH010000061 DAVMBH010000000
VERSION     DAVMBH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10827
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.061"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            128..292
                     /locus_tag="VYP30_001852"
     CDS             128..292
                     /locus_tag="VYP30_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1808795.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            376..942
                     /gene="amaP"
                     /locus_tag="VYP30_001853"
     CDS             376..942
                     /gene="amaP"
                     /locus_tag="VYP30_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1808796.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            954..1124
                     /locus_tag="VYP30_001854"
     CDS             954..1124
                     /locus_tag="VYP30_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1808797.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1163..1771
                     /locus_tag="VYP30_001855"
     CDS             1163..1771
                     /locus_tag="VYP30_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1808798.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1802..2005
                     /locus_tag="VYP30_001856"
     CDS             1802..2005
                     /locus_tag="VYP30_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1808799.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2115..2387)
                     /locus_tag="VYP30_001857"
                     /pseudo
     CDS             complement(2115..2387)
                     /locus_tag="VYP30_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2591..2878
                     /locus_tag="VYP30_001858"
     CDS             2591..2878
                     /locus_tag="VYP30_001858"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1808800.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3156..3926)
                     /locus_tag="VYP30_001859"
     CDS             complement(3156..3926)
                     /locus_tag="VYP30_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1808801.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3941..4779)
                     /locus_tag="VYP30_001860"
                     /pseudo
     CDS             complement(3941..4779)
                     /locus_tag="VYP30_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
     gene            complement(4776..6251)
                     /locus_tag="VYP30_001861"
     CDS             complement(4776..6251)
                     /locus_tag="VYP30_001861"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1808802.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKTYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6575..7930)
                     /locus_tag="VYP30_001862"
     CDS             complement(6575..7930)
                     /locus_tag="VYP30_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1808803.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGCFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7940..8257)
                     /locus_tag="VYP30_001863"
     CDS             complement(7940..8257)
                     /locus_tag="VYP30_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1808804.1"
                     /translation="MDESNLESVMGLIMYGGDAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8274..8591)
                     /locus_tag="VYP30_001864"
     CDS             complement(8274..8591)
                     /locus_tag="VYP30_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1808805.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8606..9502)
                     /locus_tag="VYP30_001865"
     CDS             complement(8606..9502)
                     /locus_tag="VYP30_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1808806.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9505..10767)
                     /locus_tag="VYP30_001866"
     CDS             complement(9505..10767)
                     /locus_tag="VYP30_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1808807.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3729 a         2177 c         1673 g         3248 t
ORIGIN      
        1 agtattaatc aaagaatttg attttttgat attaaaataa aaaaggaggg taggcagtgt
       61 tgtgatcaat tattgctgga ggtcttattg gtctcttgac aggtaaaatc actaaaaaag
      121 tagttctatg ggaatcatcg caaatgtatt cgctggttta gtcggggcat atgcaggaca
      181 atctctttta ggtagttggg gtccatcaat cgctggaatg gctttgctcc catctattgt
      241 aggtgcagcg attgtgatta ctgtagtgtc attctttaca ggtagaaagt aaacttttcg
      301 ccagtaaagt tagcaaacta tttttaaatc aatgacggga aaaatagttt aaatgttaaa
      361 tcgaaaggat tgtatatgtc aaaagcaaag aaaatatgtt tcattatttt ctgtatttta
      421 atcttgacaa ttttccttcc tgttttgata gattatcatc aagttagtga tctaggtatt
      481 catctactta gctggagaca gaactccgta gttgaattct atcttgctag atatgtcttt
      541 tgggggacag tggttctatc aactttagtt ttattatcca ttttagttgt gatgttttat
      601 cctaaacgtt acttggaaat ccaacttgaa actaaaaacg atacattaaa attaaagaat
      661 tcggcaatcg aaggttttgt tagaagtttg gtgagtgatc atagattgat caagaaccca
      721 actgttcatg taaatttacg aaaaaataaa tgtttcgttc atgtagaagg taaaattctt
      781 ccttcagaca acatcgctga cagatgccaa ataattcaaa atgaaataac taatggattg
      841 aagcagtttt ttggtattga gcgtcaagta aaacttgaag ttgcagtaaa aaattaccaa
      901 ccaaaacctc aaaacaaaaa gactgttagt cgtgtgaagt aaggaagtaa aaaatggaat
      961 ggcttaaaca atatcgatat ccaattatcg ctggtctcat aggcgtattt ctggcttgtt
     1021 tgattgtctc ctttggcttc ttcaaaacaa tatttgtatt gattttagga gcactgggag
     1081 ttgcagctgg attatatatc gaaaaaaact atatagataa ataaaaaaat aaaaattact
     1141 aatttaatta aaggagtttc atatgtcaaa cgaaaaaaac acaaatacta acgtagaaaa
     1201 gaaagatgct actgttgtag ctcacgaaat caaaggggaa cttacttacg aagataaagt
     1261 tatccaaaaa atcattggtc tttcactaga aaacgtttca ggtcttttgg gaatcgatgg
     1321 tggtttcttc tcaaatctta aagaaaaaat cgttaacagc gatgacgtaa caagtggtgt
     1381 taacgtagaa gttggtaaaa cacaagttgc agttgactta aacgttattg ttgagtacca
     1441 aaaaaatgtt ccagctttat attcagaaat cagagaaatc gtatcttcag aagttgctaa
     1501 aatgactgac ttggaaattg ttgaaatcaa cgtaaacgtt gtcgacatca aaactaaaga
     1561 acagcatgaa gcagactcag taagccttca agatcgcgta tctgacgttg ctgaatcaac
     1621 aggagaattc acttcagaac aattcgaaaa agctaaatct ggtcttggat ctggtttctc
     1681 aactgttcaa gaaaaagtta gcgaaggtgt agaagctgtt aaaggggcag caaatggtgt
     1741 agtatctcac gaaaacactc gtgtaaacta agataaaata aatataacag gagaaattat
     1801 catgtcagta gaagaaaaat taaatcaagc taaaggttct attaaagaag gtgttggaaa
     1861 agccatcggt gatgaaaaaa tggaaaaaga aggagcggct gaaaaagttg tttctaaagt
     1921 taaagaagtt gccgaagacg ctaaagacgc tgtagaaggt gctgtagaag gtgttaaaaa
     1981 catgttgagt ggcgacgata aataaggtta aaagttactt tatctttttg gtaacattag
     2041 tcaaaagagt ctgagtcgag atgattctca gaaaacaaaa agctagagat tcccaattgc
     2101 ggaactctag ctttttaatt ttgcctcttt ctcttattat atttcagcag gttgttggcc
     2161 atgagtatga atcccatgtc aattctcact tgacgcttac ctctcagatg acatctctta
     2221 taacccaaac aaacctttat ctgcccaaag acagatttca tatcaatctt acgtttagcg
     2281 aaaatttgtc tacccttgga agataaaagt gcctgatatt ctttagtttt taaacactgg
     2341 taacgttcat tcatatacag tctcttttga ggggctgatt caggttcata atcgcagtca
     2401 acattgattt caaggctgtt tgctttctat ctcccctttt tcatgatata ttttcgtaca
     2461 ggtgcttcaa tagtttctat agtaaaatga accaaaaata gtacacgttg cggtataatg
     2521 ttcttatggc atattcatta gattttcgta aaaagttctc tcctatttgt gagcgaacag
     2581 gtatagtcaa ttgattgtca gtttgaagac caagagtcgt aaggcaaagg atatggcaga
     2641 atccatccaa gggtggctgg cacaatttct agtgaacctc tttaaatcta ttacgtttga
     2701 ctgtggaaaa gagttttcaa aatggaaaga tatttccaat catcacgata gtgagagctt
     2761 ttttgcgaat ctaggatgtc caagacagcg gtgtctcaac gaacattcaa atagactttt
     2821 aaggtgtcat gacttgccaa agcagacaga tttcaacgaa gtcagtcaag aattttaggc
     2881 tgggtaaaaa ctcaatttca ggagaaaatg aaataaatat tcccacaata aaatgcatag
     2941 tatcaaagtt tttccaacac ctgatattat gcatttttta attttaaaga ctttttccca
     3001 gcctcaagaa atcacatccc acctaaatcc tttggatacc aaatacctca tcaggtattt
     3061 tctgagttgg taagactgtc tagcttaatt tgacaaatgg agggcgttaa atccagtttt
     3121 tacaggaagt ctatttaaat attttcacac tgaccttaca aaatatgaaa taaattatat
     3181 aaagtcattc ccatgacaaa gaataacatc cctttaaaac agtatcttac ccaattttca
     3241 ggtaagactt ttgatacaac cgtccccaat acccctccgc atatagaagc aagaaaaata
     3301 actggaacag gtgctaaatg atactgattt aaacctgtaa ccacaacaat tgtagccaaa
     3361 tgagacaact gggaaaagaa aataattgca agagaataca tcgttgcttc ttttatcgaa
     3421 atagaaaaaa acaccatcaa taaagataca ttgagcggac caccaccaat ccctaaaaaa
     3481 ctagaaatca agcccaatag aagaccacaa atcatataga atcctatctt atcaaattga
     3541 taagtttttt taaaatctgt taaaacaaat gatacaagta gcatcacaaa tagtaaaatc
     3601 atttgaacaa tggatactag ccgtactgat aattgagata acaaaacttg aaaaataaga
     3661 tgacctagaa accctcctaa aacagaagaa aaggataccg taaaaatcaa tctccatttt
     3721 atctctttac tttgtgaaaa tcttttggtt gttgaaataa tcgccattat aaaaacagag
     3781 aaactagaat aaaaagcaat atcactgacc gaatggtatc caaaactatc cataagtggc
     3841 ttaattataa ttccaccacc catgcctgat atagaaccca atccactagc tattataatg
     3901 attagaaaat aaataatctc aaccactttt taagtccatc ctattctttc aaacatctaa
     3961 aacctagatg gctactagtg gaagtagaaa tacatccatt tctagcagct actcggtatc
     4021 gattacaata agaacaatga cataaaaagg aacctcctct gatagcatac tcctcatctt
     4081 gtatcccata ttttggtaac tcatagtcat cttcattaaa actagctaat aaggtatatc
     4141 tcggattgcg acaccattcc caatcatttg atatagacca aaatcattag gtaaaaattc
     4201 atagacagga gccgttccta taaatccatc taaggcagta ttttcataag gaaatcttcc
     4261 ttgccaagta ttggcatgat aatatccacc ttctaaaaga gtatctcccc aaggatattc
     4321 agattgtctt cctcctctag cagcatattc ccactgtgct tcagtcggta aagacattcc
     4381 gctccaatta cagaaagcca atgcatcttc taaagcaaca tgaactactg gatggtcttc
     4441 taaacccact agattactgt tctcaccgta gggatgtttc cagcaagcgt tcgaaacttg
     4501 taaccaccac ggagccccag caggatgagg atatccctcc ctttctgcct ccggaacgaa
     4561 caatataaaa acaaaagacc actcttgtcg ctcagctagt gttttatagc ctgtttcttt
     4621 cacaaattga gcaaattctt gattcgtaac tggagtatcc gcaatggaaa aatcctttac
     4681 actaacagcg acttgaggac cttcaaaatc atctaaaaag ccctcttcag aatttgttcc
     4741 catcataaat gtcccaccct tgattttttt cattttcatg attgactatc ccccgttttc
     4801 gttagagttg gcgttatttt agaaagttca acaggaacta actcttcatc cacaacaaaa
     4861 ccttcttctc tatatctaag aaagtctact aattttttct tcatctgacg aacaataggt
     4921 tgatattttt cacttggata caaatcattc atttcatgcg gatctttttt catatcaaat
     4981 aactgataat gatttaaaac aggaaaccag ataaatttcc actggtctgt caaaatatat
     5041 tgactagaat cttttcctaa agcatgttca ccatgaaatt ctgttcgcca cccctcgtac
     5101 tgtccaaata ataaattctt aacactccgt ccatctagtt catctgtagt agttcctcct
     5161 gccaaatcca cgagtgaagg aaaaatatct tgaattttca ctaattgctt gattgttccc
     5221 ctattaccag ctatcaatcc agccggatcg taaataaacg aaggaatgtg gatacttccc
     5281 tgataaggat atccctttct aaacagataa tgttcaccaa gctgatctcc atgatccgaa
     5341 acaaaccaga taatcgtatc tttatcatga cgaaattctt ttagggcagt caaaaagcga
     5401 ctaatttgat ggtctatatg agtaatcaat ccaaaataag cagcaaccat tcttctttga
     5461 tcatcttcct ttaatttccc tcttaaagca taaatagacg gaatttgctt ttctaatact
     5521 tcccaattcc cgatatgcaa atcgagaaat tgaggcaagc gttccatata catatcaaaa
     5581 tagtattttg ggggatttaa tggagcatgt ggtttttcaa aagacatttt gagaaaaaaa
     5641 ggaaccgttg gatctcttct ttgtaaaaat gaaatagact cactcacaac ccagtttgtt
     5701 ggatgtaact tctcatcttt atcccaaggt ctagcttccc aggaattaca atccattccg
     5761 tcatcaatca aatcaacatc ataaccaact ttacccttta aaaaggctag atagtcacta
     5821 gcataatcaa attgacttcc ataagtctta tcatactttc tatcaacatg tagataccca
     5881 tcgtgaagta atacatgatc aaacccaagt ctctgtctgg aaggaaaaac atgcatctta
     5941 ccaatacact ctgtttgata acccatatct ttaaagactt ttggaagagt attagtaaaa
     6001 ttccaaggca cctcatcttg ataaccaaca cgtccacttt tatcttggtc taagccagtc
     6061 aataaagctg ccctagcagg aacgcaagaa ggaactggag aataggcatt ttcaaaatta
     6121 taacctacac tagccatcat atctaatgtt ggagtgctaa ctagcttatc cttactattc
     6181 aaggataagg cgtctgctct catttgatct acaacaatca aaataatatt tggttgtttt
     6241 gtctgaacca taaaatctcc tttctaatat ggcaaaagag gcacaagaag atatctacct
     6301 ttactgcacc cctttctata tcaatctctc tatataaagc aataacattc ttgttatgtt
     6361 ttatagaaaa atgaactaaa atatgactaa atcgattagg aaattcaaat cattttctag
     6421 tactatttta gaagttacag tgtactattc caacttcaat aaactataaa cctttgtcta
     6481 ataacaattt tagtggagat aagaaatcct acacctaact caatcttaca cgtaatctat
     6541 ttctatttta tcacaaaaaa cgcaagtaag accattaact caattcagtt ttatctgcca
     6601 ttttcacaaa tgggaaataa gtcaagacac taataatcaa acaaacaact gataagatga
     6661 tggcacgcca atcaaatgct gtagagaagc aaccatataa aattggaggc attacccaag
     6721 taacattttg tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa gctaccgttg
     6781 ccatgaaaac cgggctaagt acaaatggta taaatagcaa aggattcaag acaactggta
     6841 aaccataatt taccggctca ccaatattaa acagaactgg tgctagacca agtttagcaa
     6901 cttttcgata atgactgttt cttgaaaaaa ttaaaatagc aagtaccaat cctaatcctc
     6961 caaaccagac aaacgcccca aaagacccac ttgtccatat ataaggaatc ggttcacctt
     7021 tttggaaagc atccagattc gctaacatag caactccaaa cagcccttcc atgatgggag
     7081 ccaatacatt tcctccatgg agaccaaaaa accagaataa cttatttaaa aagatcatca
     7141 gaataactgc aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac accttgtaaa
     7201 cccaatcaat caataagtca ttgctaagta aatggaaaac ataagtcaag atggctacta
     7261 tatacatcgc cataaatcct ggaatgatag aagtgaacgg cttagcaatc gcagggggaa
     7321 ctgaatctgg taacttgatt acccagttct ttttcattac tttacagaaa ataatagagg
     7381 ctaaaaatcc aatcatcatg gctgtaaagt agcctctggc attaatatgg tttcctggaa
     7441 tcacattccc aatagttacc atcagatttt taccatcaaa tgctagatta tcaattcctt
     7501 gtaagatttg atctaatttc acatctccta catttgccaa agggaaactc tttgtaactg
     7561 tacttccaat cgaaatgaca aacgaagcaa gcgataccaa accagcagaa actgtatcaa
     7621 ccttataaat cttagcgata ttcactccca agcaatagat gaacaataag gaaacaattg
     7681 gtatacttcc cttgaatacc aaattattga tgtcaacaag ccactgaaag gttttcgtaa
     7741 tactttctag gtgaaattgt tgtggtaaat ccactagaaa agcatttaat aacaaagcaa
     7801 tggaacctgt cataataaca ggcatagtcc ccacaaatga atcacgtaaa gcaactaaaa
     7861 acttctgatt cccaactttc attgcaattg gagaaagttt ttcttgcatt ttatccaaca
     7921 ttgtattcat agcaaattcc taattttttt caaatcgttc gtatacttct accacttctt
     7981 tcgccaagtc aacaaaggtc agactcgtca ttaaatgatc ttgcgcgtgt accatcaaga
     8041 ggctaattga tgtttcttcc ccctgtgcct cttttgtcaa catttctgtt tgagccttat
     8101 gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg attggcttta gagaaatccc
     8161 ctttttttgc tgcctgaata gcctccatag cattactttt ggcatcccca ccatacataa
     8221 ttagccccat tacagattct aaattacttt catccataac attctcctca atcttagtct
     8281 aataaacttt cagctaaatc taaaacttta gaaccattca tcattccgta atctgtcatc
     8341 ggaataaccg ccacaggaat ctgtctatct tttagttttt cttgaaagtc ccctagtaaa
     8401 tagcgaactt gggggcctaa aagcaacaca tttacttctt ttgttgctac aatttcttct
     8461 gcttcaggag ctggaactgc aaaaatttct gcatccaacc ccttatcttc tgctgccttt
     8521 tgcatctttg tcactagcag acttgtactc atacctgctg cacatgctaa cataattgtt
     8581 actttagcca tagcttactc ctttatcacc tatttactga cctagccaag cgagatactg
     8641 tatgtctcac tcctctaatt gccttgctca atgcataaat attatcgact gttgccagtc
     8701 ccccatatcc tgcgtcacct atatgttgaa tatcaactcc acaaatttta tttctaagtg
     8761 caatttcctt aatagtatct gtatcagatg tttcttggct agtaccaata gcactcaata
     8821 caagaccacc cttactatga acgagatcaa cgacttcacg caactcttgg tcatgaaagg
     8881 ctggaacggt tccaactgct ggaacaagta tcacatccgc acctgcttcc aacaattgct
     8941 ctgcgacaga aagctctgcc acaggctcat tcactcctgc cccgtgcatc ttacctgcaa
     9001 taatcaaacc agaaaagttt tccttagcag tttgaacagc cttaatgatt tctcgattgc
     9061 taactcctgt tccaggattt ccagtcaaac agacaaagtc aaaacctaac tcctctattc
     9121 gattcaatgt ttcaacacta gcaacacgac ctgcaacaat ttcctgtgtt tcctctagca
     9181 tctttgcaga tgggtcaatc ggttccaaat ttacaccaat tggacaagca acaagctggt
     9241 gtaagcgatg aataacatca tcacctgaac tatccaaagc ataaatttta ggctcaaaaa
     9301 catcaacaca attcaataaa atcatatcag ctccaaaagc tctagcaatt tcagaattag
     9361 ttatatcccc aacaaatgtc tcacgagtaa ctacattttc agatagaaca actctacctt
     9421 cacttgctaa aatactttgt tttaattctt cagcattcat ctgtaatatc tcagatggat
     9481 ttgcactaat taaacgtttc attctcaatc ctccaataac ttaaaccgtt tttcaatagc
     9541 tattacaaat ggtaaataaa gtaagacatc caaaacaatc aatacaattt gtaataatga
     9601 accagaaata cttcctgtag caagtaaacc acttataaca ggtggcatag tccaacctgg
     9661 atctgtataa gttagcggaa ccaaacctga tgccattgct ccccacgcta ctagtaagtt
     9721 aaacattgga gctaagataa atggaactag taacaaaatg ttcaaaacaa taggaacgcc
     9781 aaacattgct ggttcattta tattaaataa tccaggtata acagttatag gtgccaaagt
     9841 ttttagttgt ttactagctt tcttcttatg tgctaaatat cctaacgcaa gaactaaacc
     9901 tatggttgca ccaccgccac ctatgaatac aaaattatcc ataaatacgc tagtaaaaat
     9961 atttggaaga gtttctccag tttgataagc tactttattt gcatctagat tagctaacca
    10021 taacggtttc ataactgcat taacaacatt tcctccgtgt aatcctacaa accaaaaact
    10081 actattaagg aaaattaaga taagaagacc aataacatta tttcctaaaa gtccaagtgg
    10141 acctcccaaa gctacttgag caatttcatg aagattaggt aaacttaatt tatctaaagt
    10201 tgcataaaca atcaaccaac caacaatagt cactgcacca ggaataatgg cactaaagct
    10261 tttagatact gctggtggaa caccatccgg catttttatc tgtatattat gatttataaa
    10321 ccattggtag atatagccat taatcaatcc taaaatcata gcaacaaata aaccttttga
    10381 tgccatgaaa gcggtaggca ttcctgctcc agcctctcct gtaatgaaag gcgtaactgt
    10441 aataaaagat gataatgaca caataccagc aggaatacca tcaactttgt attgtctagc
    10501 cataaagtaa gcgataccaa aactagctac aagaccaagt aatccaaaac tactatcaac
    10561 acccttccat aaatagtcag caacaccaat atcacccaga tatttttccc atcctggaat
    10621 aggaaaactt gcaataacca ttagtaatga acctatcaac aataaaggta tagttagagt
    10681 aataccgtct cgaatagaaa ccaacgcttt attattaccc aatctagccg ctactggaag
    10741 taacttttct tgtaataatt tttccataac cttttcctct taaatatatt ttattatcaa
    10801 aagttatcat ttatctttat tttttga
//
LOCUS       DAVMBH010000062        10752 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVMBH010000062 DAVMBH010000000
VERSION     DAVMBH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.062"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(115..1539)
                     /locus_tag="VYP30_001867"
     CDS             complement(115..1539)
                     /locus_tag="VYP30_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1808808.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFAIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2082..4361)
                     /gene="pulA"
                     /locus_tag="VYP30_001868"
     CDS             complement(2082..4361)
                     /gene="pulA"
                     /locus_tag="VYP30_001868"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1808809.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4473..6431)
                     /gene="ligA"
                     /locus_tag="VYP30_001869"
     CDS             complement(4473..6431)
                     /gene="ligA"
                     /locus_tag="VYP30_001869"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1808810.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6524..7702)
                     /locus_tag="VYP30_001870"
     CDS             complement(6524..7702)
                     /locus_tag="VYP30_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1808811.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7782..8645)
                     /locus_tag="VYP30_001871"
     CDS             complement(7782..8645)
                     /locus_tag="VYP30_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1808812.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8648..10549)
                     /locus_tag="VYP30_001872"
     CDS             complement(8648..10549)
                     /locus_tag="VYP30_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1808813.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3226 a         2380 c         1909 g         3237 t
ORIGIN      
        1 ctgtactatt ctagtttcaa tatactataa taccaaaaag ttcgtatttt ttctataatt
       61 attattttat agcaaaaaaa taaaaccagg aaaacaattt cctgatttta cacgttattt
      121 cacatcaaaa acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg
      181 cactccagct ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt
      241 tttattatta atgtggactg tacctacttc aagtttttca gcaattgcaa aggctttttt
      301 gaaatcattt gtaaaaactg atgattgaag gccgaattca gattcgttgg caaaagcaat
      361 agcctcctct acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca
      421 tgccactttc atatcttttg taacttggtc aaaaagcact ggccagagga gattgccctc
      481 acgtttgatt ggtgtaagag cctgagcctc tttttcttgt gcatcctcaa tcaagcccca
      541 aatgaagtcg gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc
      601 accaactgtt aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact
      661 ttcgagaaca atgacacgtt taatagccgt gcaacgttgt cctgagtagc taaaggctcc
      721 cgcaacaatt tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc
      781 tttcccacca agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc
      841 aataggagtt gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc
      901 cccaatttct gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc
      961 ttcaaatgct ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat
     1021 gaccacattc cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata
     1081 attaaaggga gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt
     1141 gtttttactt gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc
     1201 ttcctcagca gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt
     1261 aatccctttt gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa
     1321 aatagctgct gttttatgca aataagccgc acgttcaatt gctgataaag ctcgccatgc
     1381 tggcagggct gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg
     1441 aactgtaccc aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga
     1501 tttccatttt ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg
     1561 attaagatat attttaccaa attttcagaa aaccacaacc ctttttgcga aatttttgag
     1621 attattttca caagcttgat ttttcaaagt atactcaata aaaataaaaa aatccactac
     1681 gtcaaggcga ggctaatgtg gtttgaagaa attttcgaag agcgtgaatg agtatcatct
     1741 atagtaaaat aaaaaactga acaatttggt ttgggacagt caaaccaatt tctcacaatg
     1801 ttttagaaac aagggtgtgc tattccaatt tcaggctact ataactgtca tagattgctg
     1861 aaacaaagtc taggtaaaag tcttcataat aaaaagacct cctatcaaat gttcaaaaac
     1921 tttgatagga ggtcttgttt cgtgaaaata tttatcaaat tttctataca agtgagctgt
     1981 tagccaggtt ctttctattc tttcaatttc aatgaatgga ttttttacca atactcataa
     2041 ctgggaattt ttctgtctaa aaatagcgag atagatggta tttataaaac actcaagaca
     2101 gctagactaa tatcatttaa aacattatct tcttttgagc gactgttggt taccaacata
     2161 gctaaatttc ctgcattttc aaattgatag ggttctgatt tagcattcac aactaccaag
     2221 aggtgttctt tgccgtgaac ttcatagata aggcagccgc tatgttcaat cgcagaatgc
     2281 acaaagacat gatggtaaat ttcatcatag ctagagtaag aaaaggcacc agtttttgtc
     2341 ttcaatcgga tgacttgacg gataaactca atactgtctt gacgctcatt aatcaagttc
     2401 cagttcactt ggttcacact gtcaggagca ttatagctat tcatcgcacg ctctctatca
     2461 tcatgggtca actcaccatt ttcaccagtc gcaaccagtt tggtacgacc aaattcttga
     2521 ccgatttcca taaaggccat cccctgcatg agcagattca tggctgtggc agtttcgacc
     2581 ttgcgcatga tttgctctga actttggtct ggatgaaggg ttgccaataa atcgtgaaga
     2641 ttgtaattgt catgggcttc tacatagtta agcacctgat ttggatgtgt atagcttcct
     2701 aattcacgac tccctaggat tgctttagct agaattggct ctgtcgcagc accactgaca
     2761 aaacctgact tgatagcacc ataaacttct ccccctttga cagcatcgcg ctgattgtca
     2821 ttaaagaaac caatatttgg catctggtag gcattgtcct tcttggcctt atcataaggg
     2881 gcaagacctg ttcccatatc ccatccttct ccatagagga taatgttgga gtcgatttca
     2941 tccaagcttt gacgaatcat ctgcatggtc ttgacatcat gaatccccat caagtcaaaa
     3001 cggaagccgt caatattata ttcctgcacc cagtatagaa gagaatcaat catatacttg
     3061 cgaaacattt cgtgttcact ggctgtttca tttccaacac ccgttccatt ctggaaggta
     3121 ccatctggat tcatacgata atagtaatca gggactgttg tttggaatgg tgcatcaaca
     3181 actgagaagg tatggttata gactacatcc ataatgactc caatacccgc atcgtgataa
     3241 gcttgaacca tcaccttcaa atcacgaatg acctgagctg gatcatctgg attagttgaa
     3301 aaactagttt ctggcgcgtt atagttttgt ggatcataac cccagttgta ggttacattt
     3361 ccatcctcat cgtattcttt atgacggtct gcaattggtt gcaattgaac ataattgtag
     3421 cccagcttct tgatgtaatc aaaagcagtt gactggccgt attggttaac tgttccagcc
     3481 tgagcagcac ccaagaaagt tcctcgaaga tgttcatcta cacccgatgt aggtgattta
     3541 gtcaaatcac gaatatgcat ttcacagata actgccttac atggattttc caagcgccaa
     3601 gtagcctccg aaccgtgctt aacctcgaag ttttcaactt gcttttctac atggctcaga
     3661 atagctgaac gtttgccatc agggctggtc gcgattgtat aaggatcacg tgtcagtgtt
     3721 tggtgatgag ggaattggac ttgatactga taagccttac ctaccaaatc ttcctcaaca
     3781 tccaaactcc agacaccgat tgtattgtcc ttatgattat aagagtagct attgcctctt
     3841 ttcatctcaa aagtcttcca aacgggtgca tcattagcag ctgattcata aacgacaact
     3901 tgcacttctg tcgctgtagg tgaccagagg gaaaaatgag cctgattgtc ctctacacgg
     3961 caacccaatt ctccttggta accccaatga tgatcaaaac tagcactgtt aatggcctta
     4021 tcaaaggcaa aaggattttg atttttatag aaaggactgg caatagcagg attttcagag
     4081 taataaatcc tatcatcgcc ttccaaaatc cagacctctg ttaatagggg atagtgatta
     4141 aaacggatag aatattcttt actagtttga cctgtatgaa ccacaaaatt caagctttct
     4201 ataacatgtg aacttgggtg ttcaaagcta aataaagctc caaaataatc ttctttgtag
     4261 gttagcaaat caattcgttg atcctgactt tttacaaagg agcaagtgtc atattctcca
     4321 ttcttacgat ggtaatgaat gcgcataggg tagttataca ttttttattt ttccttttta
     4381 ctttgtttct atttcactaa taaatttttg tcaatctcgt ctcaattaac agacatagtc
     4441 atattctcta aactctgttt ttaaacgatc cattacaaac tttctagcca tgcctcatct
     4501 ctgacctgga taccaagttc ttgtgctttt tgcagtttac ttccagcgtc tgcacctacc
     4561 acgacgaggt cggtcttttt agaaacacta cctgtcactt tggcacccag actttcgagt
     4621 ttacttttag cttctgagcg cttgagtcgt tccaattttc ctgtcaatac cacggtcaaa
     4681 cctgacaagg ccgcatccgc tactaccgtc tgtcctttat agtccagatt gaccccagtt
     4741 tctttcaatt ctctgagcag aatttcagag ccttctgtcg caaaataagt ctgaagactt
     4801 ttggcaatca cgccacctag actttcaata ctagccactt cctctgaatc tgcctgagac
     4861 agattttcaa ttgaatggaa atattgaagt aaaagctgac tagccttgct tccgacatga
     4921 cgaattccca aaccaaataa gagcttctcg gcagaatttt cctttgatgc ttggatagcc
     4981 tgatacagtt tagcagcgga cttttcctta accccctcta aaaggaggaa atcctcttct
     5041 tgcaaacgat aaatatccgc cacatccttg actaaattag cagcaaaaag cttctcaaca
     5101 atagatggac caaggcctgt aatattcata gcatcacgag aagcaaagtg aatcaagcct
     5161 tccatgattt gagcagggca acgcggattg atacaacgta gggccacttc atcttcaaag
     5221 tgcaacaagt cagagttaca acttggacag tttgtaggga tatctagttt ttcttcagaa
     5281 acccgtttgg actctaccac acgtaaaacg gcagggatga tgtcaccagc cttatataca
     5341 atgaccgtat cgtcttttcg gatatctttt tcagcaatat aatctacatt gtgcagggtc
     5401 gcacggctaa cagtcgtacc ggcaagttgt actggtgtta gattagcagt tggagttaca
     5461 acaccggtac ggccaactgt ccagtcaact gataagagtt gagcttcttt ttcttcagca
     5521 gggaacttgt aggctactgc ccactttgga gccttaacgg taaaaccaag ttcttcttga
     5581 cttgctaggt cgttgacctt gattaccact ccatcaatat cgtaaggtag attttcccgt
     5641 tcctgtccta cttcttggat aaaattccag atttcatcta tgttttcagc caagattcgc
     5701 ttaggattga ccacaaaacc tagttgttct aggtacttca aacccttttc ttggctatca
     5761 cgagttgaag ggctggcttc ttgatagaga aacgttgcaa gattacgctt ggcaactact
     5821 gctgtatcca actgacgcag agttcctgct gccgcattac gaggattagc aaattcaggc
     5881 tctccatttt cttggcgcac ttggttaact tggtcaaagg aagcgcgtgg catgtaacat
     5941 tccccacgaa ctgtgatatc tagttcttct ggcaaagtca aagggatgtc cttaacacgc
     6001 ttgaggtttt ctgtgatatt ttcaccaatt gaaccatctc cacgtgttac cccagcaacc
     6061 aaaatcccct tttcataagt cagcgagata gataagccat cgattttcag ctcacaaata
     6121 taggtcggat gagccacttc cttacgaaca cgcgcatcaa aagcatctag ctcctcacgt
     6181 gaaaaagcat cctgcaaact ataaagagga tactgatgac tgtatttttc aaaaccatct
     6241 aaaaccttgc caccaacacg atgagtcgga ctgtctgcta gcacttgctc tggataagca
     6301 gtttctaact cgaccaactc acggtaaagg cggtcatact cactgtctga aaccgaggga
     6361 ttatcgctgg tatagtactc agtcgcatag cgattgagca aagcgactaa ctcattcatt
     6421 cttttattca taagaccatt ttaccataaa acaagccctc ctcacaaacg agaagggcgg
     6481 aaaaaacact tagtttgaaa ttatttttga aactcaagca accttatatc aatttttcaa
     6541 aatgagttcg aacataaata aacgatatac aagacaagat gataacacca cttccaatta
     6601 tcaggaaaga agagagatgt acacttggca agactgtcat aaatcctttt gcaataggca
     6661 taaatagaat agctaaggta aaaattgtac tcagtactct cccaagaaat tcgctctcaa
     6721 ccttggtttg tacttgagta aaaaagtgaa tattaaaaat cgtcataaac aattcacaaa
     6781 ctaaatttcc agaaaaggaa agaaaagttg gaagtggtaa tcccatcata aaaactccga
     6841 cacctgtcaa agccagtaaa atcaaaagat tataaatatt agctttaatt ttactagcta
     6901 gaagagcccc aatgatggaa ccaatagccc ccatagttaa aatacttgca taggctcctt
     6961 ctgacccgta aagctgattc gaaaagggaa gtagaaattc aaaagctgca aaaaagaaat
     7021 taacgctgga agctaccagc aaaaggaaga aaatttcttg ctgatgccag atatagtgta
     7081 acccatcctt gatatctaca aaaatatctc tcccagtaaa agcctttttc tcttgaactt
     7141 ttgcttcctc ttttggaagg aaagccacta gaacaaaagc aatgaaaaaa gtcagcgagt
     7201 ctagcagtag cgtcatatgg agacttgcaa actgtaaaac aaggaaggaa agaacaggag
     7261 agctaacacc tacaacctgc aaaaccagct ctaagcgaga attatagatc acaatctcat
     7321 ctttctccac cacttcagtt atgatagctt tattggctgt gcgagaaaag gcaaaagcaa
     7381 tagcctgcac aatgttagca acaatcaaag cgccaatcat ccagctatca ttccttatga
     7441 aagaaatagc cagacaaaga atcccacaaa caagatctgc cgtcattaaa atcttacgac
     7501 gagaaaaacg gtctgaaata actccgccaa agggattgac gagaatagat gtgacgagct
     7561 cagaaatctg atacattcct aaaactgtct gtcctatagt ccccatagaa gccaaccaga
     7621 cactatttcc ataatcatag agcatatttc ccattttatt gatagcccca cggctaatca
     7681 actgcactgc atagcgattc atattaaagc tcctctcaaa ttttgaaact attgtatcaa
     7741 aaccgaaagg agctttttat tttttccctt atttgggaaa attaactttt gacaaatttt
     7801 tcgtagtgtt cctgataata ggctacttgc tctggaagac ctaacacatc aaaaatatgc
     7861 atggcctctt gcatctgctt acagccttct ttacactgtc ctttttgata taaggcaaaa
     7921 ccttttaaat aatggaaaac attacgctca taaagcttaa tacctttgtc aataatcttc
     7981 tctgtataag cctcaaaata gttggcatta taaaaagaag aatgctctaa acaatgctgg
     8041 taacaattga gggccaaaat caacactaat ctcttatggc gactaatctc ttggtaaaat
     8101 tcctccctct ccataacttc tctaccaatc cgagtgacat agtctacatc gtagaaacta
     8161 tagaggttac cgaaaagaat caactcatac atggtccatt cttctgtttt gaagagataa
     8221 tctgctacct tatccaaatc atcctgcttc atatcataac tcgcatctct ttgacaaatc
     8281 agaccttgta gcaaaatcca gttcagctca aaataaaggg gagtcgtcga actcttagac
     8341 ttttcaagtt gttctctttg aagcttttga aaacctgcaa tatcgtttga atagtaaagt
     8401 gggataatct gtgccatcat agacacatgt tcatgattat gaaaattcct tgccttatcc
     8461 atgaaatttt cgattgttac atgaatgtta tccaaaatct caaagaaacg ggagactgcc
     8521 aggtcagact ccccaagctc aaagcgagat aactgagagg tagagcagga ttcgcctgct
     8581 gcttccttta aagaataatt tccacttgtt cgaaattcac gaaatacttt tccaagatgt
     8641 tccatcttta cacctgctct gataattctt cccactcaag catagcttct tcctgacgat
     8701 ggctgatttt gtccagctca gcctgtaatt ccatgagttt gtcggcatcg tttgtttcca
     8761 acatttgttc agaaatggct tggctttgac tttctagctc ttcaatttca gcttctagac
     8821 tttcgatttg tcgcatgagt ttgcgaactt ctttttgact ttctttctgg gcctgatagt
     8881 cattgactgg acttgcttcc tttgcttgat tgctagttga agcttcctca gtctgactca
     8941 tttctgctgt tgctttcttc tcaacatagt agtcgtaatc tccaaggtag agagttgaac
     9001 cattctcaga caattccaaa acatgagttg ccacacgatt gataaagtaa cgatcatgac
     9061 tgacaaacag caaggttcca tcaaagtcaa tcaaggcatt ttctagcact tccttactat
     9121 caatatccaa gtggttggtc ggctcatcca gaatcaaaaa gttattgttt tccatagaca
     9181 atttagctaa aagcaaacga gctttttcgc caccagatag catgccgact gattttttaa
     9241 catcatctcc tgagaaaagg aaggctccaa gacggttgcg gatttcaact tctggtgtca
     9301 gtttgaaatc attccagagt tcatccagca ccgtattact tggtgtcagc ttgctttggg
     9361 tttggtcata gtaaccaacc tcaacattag cgccaaagcg cttttctccc ttgataaaag
     9421 gaatctggtc cacaatagac ttgataaagg ttgacttgcc gataccattt ggaccaacga
     9481 tagcgacagc attcatctta cgaagatcta ggttaatcgg ttgtgacaag acttccccgt
     9541 catagccaac agctgcattt tcaacagtca aaacaacatt gcccgacgtt ttttcagact
     9601 ggaaggtcat gttggctgat ttcttgccag cttcaggctt gtccaaacgt tccatttttt
     9661 ccagttgttt acggcgagat tgagcacgtt tagtcgttga agcacgaact agattgcgat
     9721 tgacaaagtc ttccagagca gcgatttcct tctgttgctt ttcatagttt tttgcctcag
     9781 taactagctt ttgctccttc aattcgacaa aacgagagta attccccaca tagcgatcca
     9841 aggaatgctt ggtcaaatct agcgtaattg tcgcaacctt gtccaagaaa taacggtcgt
     9901 ggctgacgat aatgagggca ccgctatagt ttaccaagta attctctagc caggcgatgg
     9961 tttcaatatc caagtggtta gttggctcgt ccaagaccaa gagattgggc ttttcaagga
    10021 gcattttggc aagtgccaaa cgagtatttt gaccaccaga aagctcagca attttcatct
    10081 gccacataga ctcgtcaaac ttgaatccat tcaaaatcgc tcgaatatca gcttcatagg
    10141 taaagccacc tgcttggcga aaattctcag ataagcggtc ataatctgac atcagtttat
    10201 ccaaatcctc accagacttt tcacccatct ccagctccat ctgacgcagt tgtctctccg
    10261 tccgacgcaa atcattaaag acatgaagca tttcatcgta gatggtattt tcagactcaa
    10321 aacggctatc ttgggctagg taagacagag aaatatcttt tttcttattg atttctccgc
    10381 tagttggctc ctcttctcca actaaaatct tcaaaagagt agacttacct gcaccatttt
    10441 tcccaacaag agcaatccga tctcgttcat caacctgcag gttgatatta tcgaaaagaa
    10501 cctctcctgc aaaagaacgt tcaattttat tagcttgtaa aataatcata caagtagtat
    10561 agcatgtttc cctaaggcat tcaagataat cgtaagtctt ttagtacaac ttttataaca
    10621 taaaataaac taaattatgt atattttata ttagatttct tcactatctt gttggatttt
    10681 ctaaccagct aatcttgttt caaatagtta tcgcacaagt ctattattta attcttttca
    10741 tcatttacgt ac
//
LOCUS       DAVMBH010000063        10578 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVMBH010000063 DAVMBH010000000
VERSION     DAVMBH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10578
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.063"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            212..892
                     /locus_tag="VYP30_001873"
     CDS             212..892
                     /locus_tag="VYP30_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808814.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLETISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            852..1232
                     /locus_tag="VYP30_001874"
     CDS             852..1232
                     /locus_tag="VYP30_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1808815.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            1242..1529
                     /locus_tag="VYP30_001875"
     CDS             1242..1529
                     /locus_tag="VYP30_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1808816.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            1530..2288
                     /locus_tag="VYP30_001876"
     CDS             1530..2288
                     /locus_tag="VYP30_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1808817.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLIHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAITDRIIFLDQGKI
                     AEEGTAQAFFTNLQTKRAQEFLNVFDFSQFGSYL"
     gene            2300..3171
                     /locus_tag="VYP30_001877"
                     /pseudo
     CDS             2300..3171
                     /locus_tag="VYP30_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(3258..3905)
                     /locus_tag="VYP30_001878"
     CDS             complement(3258..3905)
                     /locus_tag="VYP30_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808818.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3902..4600)
                     /locus_tag="VYP30_001879"
     CDS             complement(3902..4600)
                     /locus_tag="VYP30_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808819.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(4610..5362)
                     /locus_tag="VYP30_001880"
     CDS             complement(4610..5362)
                     /locus_tag="VYP30_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808820.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCHQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(5362..6126)
                     /locus_tag="VYP30_001881"
     CDS             complement(5362..6126)
                     /locus_tag="VYP30_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808821.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(6222..6625)
                     /locus_tag="VYP30_001882"
                     /pseudo
     CDS             complement(6222..6625)
                     /locus_tag="VYP30_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6805..7437)
                     /locus_tag="VYP30_001883"
     CDS             complement(6805..7437)
                     /locus_tag="VYP30_001883"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1808822.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(7471..8172)
                     /gene="pyrF"
                     /locus_tag="VYP30_001884"
     CDS             complement(7471..8172)
                     /gene="pyrF"
                     /locus_tag="VYP30_001884"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1808823.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            8493..8585
                     /locus_tag="VYP30_001885"
                     /pseudo
     CDS             8493..8585
                     /locus_tag="VYP30_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(8907..9620)
                     /locus_tag="VYP30_001886"
     CDS             complement(8907..9620)
                     /locus_tag="VYP30_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808824.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(9613..10452)
                     /locus_tag="VYP30_001887"
                     /pseudo
     CDS             complement(9613..10452)
                     /locus_tag="VYP30_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061739.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
BASE COUNT         3492 a         2170 c         1730 g         3186 t
ORIGIN      
        1 tgtcctcctt aataagtaag cgtttacttt gtatattata aaaatatctt aactcttttt
       61 tcaaaacttt tcaaatattt tgtttggaaa tttcagaaat tttatgtcta tggtaaaaaa
      121 atccttataa cggcaataaa aatagatatt atccaaagaa gattttaagt gctacaataa
      181 ctgtattatt tctagatggg aggttctatt tttggattgg tccattgttg aacaatatct
      241 accactatat caaaaggcat tctttctgac cttgcatatt gcagtttggg gaattttggg
      301 atcctttctg ctcggtttaa tcgttagtat catccgacat tatcgaatcc ctgttttggc
      361 gcaagtagcg acagcctaca ttgaattgtc acgtaatacg ccccttttga ttcaactctt
      421 ctttctctac ttcggtcttc cccgaatcgg cattgtccta tcttcagaag tctgtgcaac
      481 gcttgggctt gtctttttag gaggctccta tatggcagaa tctttccgaa gtgggctgga
      541 aaccatcagt caaacccagc aggagattgg cctcgctatt ggtctgacac ctctacaggt
      601 ctttcgctat gtggttcttc cgcaagcaac agcggtggca ctcccctcct ttagtgccaa
      661 tgtcattttc cttatcaagg aaacctctgt tttctcagca gtggctttgg ccgacctcat
      721 gtacgtcgcc aaggatttga ttggtctcta ctatgagaca gacattgcgc tagctatgtt
      781 ggtagttgct tatctgatca tgctgctacc catctcactg gtctttagct ggatagaaag
      841 aaggacccgc catgcaggat tcgggaatcc aagtactctt tcaaggaaat aatctcctga
      901 gaatcttaca ggggttgggc gttacgattg ggatatccat cctgtctgtc ctcttatcca
      961 tgatgttcgg aacagtcatg ggaatcatca tgacctccca ttctagaatc atacgatttt
     1021 taacacgatt gtatctggac tttatccgta tcatgcccca gctggtgcta ctcttcatcg
     1081 tttactttgg cttggctcga aactttaata tcaatatctc aggtgagact tcagctatta
     1141 tcatttttac cctctgggga acagctgaaa tgggagactt ggtacgtgga gctatcactt
     1201 ctctccctaa acatcagttt gaaagtggat aggcactcgg cttgactaat gttcaacttt
     1261 actaccacat catcatccca caagtcttaa gaagactgct accgcaggct atcaatcttg
     1321 tcactcggat gattaaaacc acttcattag ttgttttgat tggggttgtg gaagtgacca
     1381 aagttggaca acaaatcatc gatagcaatc gcctgaccat cccaactgct tcattttgga
     1441 tttatggaac cattctagtc ttatatttcg cagtttgcta ccctatttcc aaactatcca
     1501 ctcacttaga aaaacattgg agaaactaaa tgtctgaaac tatcttagaa atcaaggaac
     1561 taaaaaaatc cttcggagac aatcccatcc tccaaggact ttctctagaa atcaaaaaag
     1621 gggaagttgt tgtcatcctg gggccatctg gttgtgggaa aagtaccctc cttcgttgcc
     1681 tcaacggctt agaaagtatt caaggtggag atattcttct ggatggtcag tctatcgttg
     1741 aaaataaaaa agattttcac ctagttcgcc aaaagattgg catggtcttt caaagttatg
     1801 aactctttcc ccatctggat gtcttacaaa acctcatcct aggccctatc aaagctcaag
     1861 gaagggacaa gaaagaagta acggaagaag ctttgcaatt actagagcgt gtcggtttgc
     1921 tggataaaca acatagcttt gcccgtcaat tatctggtgg acagaagcaa cgtgttgcaa
     1981 ttgtccgtgc cctcctaata catccagaaa tcatcctttt tgacgaggtg actgcttcgc
     2041 tggatccaga aatggtgcgt gaggtgctgg aacttatcaa tgatttggcc caagaaggcc
     2101 gtaccatgat tttagtaacc cacgaaatgc agtttgccca agccattact gaccggatta
     2161 tcttcctcga ccaagggaaa atcgctgaag aaggaacagc tcaagccttc tttaccaatc
     2221 tgcaaaccaa acgagcccag gaatttttaa acgtctttga ctttagccaa ttcggctcat
     2281 atctatagag gagattctta tgaaactatt caaaccactc ttaactgttt tagcacttgc
     2341 ctttgccctt atctttatca ctgcttgtag ctcaggtgga aacgctggtt catcctctgg
     2401 aaaaacaact gccaaagctc gcactatcga tgaaatcaaa aaaagcggtg aactgcgaat
     2461 cgccgtgttt ggagataaaa aaccgtttgg ctacgttgac aatgatggtt cttaccaagg
     2521 ctacgctacg atattgaact agggaaccaa ctagctcaag accttggtgt caaggttaaa
     2581 tacatttcag tcgatgccgc caaccgtgcg gaatacttga tttcaaacaa ggtagatatt
     2641 actcttgcta actttacagt aactgacgaa cgtaagaaac aagttgattt tgcccttcca
     2701 tatatgaaag tttctctggg tgtcgtatca cctaagactg gtctcattac agacgtcaaa
     2761 caacttgaag gtaaaacctt aattgtcaca aaaggaacga ctgctgagac ttattttgaa
     2821 aagaatcatc cagaaatcaa actccaaaaa tacgaccaat acagtgactc ttaccaagct
     2881 cttcttgacg gacgtggaga tgccttttca actgacaata cggaagttct agcttgggcg
     2941 cttgaaaata aaggatttga agtaggaatt acttccctcg gtgatcccga taccattgcg
     3001 gcagcagttc aaaaagacaa ccaagaattg ctagacttca tcaataaaga tattgaaaaa
     3061 ttaggcaagg aaaacttctt ccacaaggcc tatgaaaaaa cacttcaccc aacctacggt
     3121 gacgctgcta aagcagatga cctggttgtt gaaggtggaa aagttgatta gtcattaact
     3181 cttaaaagga actggatttt aagctccaat ccctttttaa gattttacct ataacatcct
     3241 gagtctatct aagatgttca atctgaacac agtgtacata ctttatcttc tattgcatat
     3301 actttatcac ataagatacg aatatcctct tcactatgac tagcaatcaa aattgttgtc
     3361 cctttttcac tagagagctt tctaaacaat gttctcatat tttctacact tgatttatcc
     3421 aaggcattca taggttcatc tagtaaaaga atagagggat tctccataat tgcttgagca
     3481 atccctagct ttttcctcat acctagcgaa taagttttaa ctttctggtc tttttgctca
     3541 tatagaccaa ctattttcag tgtatcattg atttcctgat taccaactac tcctcgtatg
     3601 cttgccaaat attgtaaatt cttaaagcca ctataataat ttataaaacc aggttcttca
     3661 atcaaagctc ccaaattagc tggaattttt ctctcaggaa caatattttc cccattgatt
     3721 aacacttctc cataagacgg actatataaa ccagctatta atttaaacaa tacacttttc
     3781 cctgagccat tcgcaccagt aattcctata atttccccct gtttacaact aaagttaagg
     3841 ttttgaaaaa cacatgtttt ttttaatttc aactcaatat tttttaatat aattatttca
     3901 ttcattctat aaacctcctc ttttgacgag tgaaatagaa aatgctttga aaaagaaaga
     3961 ctaaaaatag caactgaaga aataaatctc gtcctatatc tccattccct cgattcaaaa
     4021 tataaaatag ataattagtt cgatttccta caaatagacc accaaacaca atcatgagta
     4081 aaaagaaact aacgcaagca aagttcattt gtacattcgc tcctagtgcg tataacataa
     4141 agcaaaacaa gactaacaca caagcattca aagaatcaac tataaacaaa actcctatat
     4201 cccagtttgg taactgtaac ataaattgaa tcactagaac ttttaccatg attaaaatga
     4261 gtccataaag aaaacaggtc caaatctgat acctaatcca gagcttaata gaagaaaatc
     4321 gaatcacttc cataaagaaa tcggatgctc ttctacgata tacaattgct agaaaaaatg
     4381 tatgaataat aaaccaatga agcaaccata tagataagac taaaaaagag ttttgactca
     4441 gattaggccc ttttaaaatt tctataacaa gtctatcatt tccttctaac caataccata
     4501 atcctaaaca aatcaatatc caaaaaagaa cataacccca aaagtacttg gtatagatta
     4561 tctgattcaa cctccacatg tgactactta actttcccat ttccaacttt tacactctcc
     4621 tccagtttct atgaacagaa aatacagtca atggaattat gatagatagt aatgtaagcc
     4681 aataaatcaa tgcatacgga ttggaattta ccatatactg aaaaattggc aataatccaa
     4741 ttatcccatt gtccaactga taaatccaga ataaggattc tacaaataaa aaagtaaaca
     4801 gaaatactaa gctcatgttt gattttttaa accaagaaaa actgctaata gtaagtaagg
     4861 ataaaaagaa atagtatgct atataagaga aaaaaaatcc tataaagaaa ctagcattgt
     4921 ttgcaatact tataccataa aattctctta aaaaatcaac ctcctttatc tccaaagaga
     4981 agctaaaacc attactaaat gcaattagaa aaatcaataa aaataaagtc gccgtccaaa
     5041 tccccgtact aagagctgct aatttgaaac taaaactggt aaagtgctta attgatttca
     5101 gacgaatgcg acactccaac ctattaaaat agttattcat caaataaaaa aagaacaata
     5161 tatatgtgaa cggaaagcaa tatactccag tcgtcatatc ttgaagtaaa actaagatcc
     5221 attctaatac atttggatgg attgaatatt ggtgacagcg caataaatat actgtactag
     5281 ataaaacaca ggatagcagt aatataaaat aaaccaatac tgctaagaaa tcttttttat
     5341 aaaattgaac aaattgtttc attatacata gtcctctgaa tgtagaaaaa atgtaccata
     5401 aacaaccaaa caactaacaa ataaaataaa agcaagatgc ccactaacta aggaaagact
     5461 gatatctttc tgatatccca aagctagcgt tgtcacaggt tctaagtaag atagccctaa
     5521 aatagcccat aaaataccac caaccatcat ataggcaact gggatgaaaa tagctcctaa
     5581 ttttttcttc actagcaaag cactagctag tccaaaaata gagaacacag cgccccaaac
     5641 tccataccag agagtcgtca caagactata gagcaactga ttagaatcaa ataattcttt
     5701 taaggcacca ctataatctc caatataaat ttcctgataa ggagtcacta aaagattaat
     5761 tcctaataat aataaatagg ggagaaaaaa gactagaaaa gaagaaataa ttacagtact
     5821 acccacaata gccagatact tctttttaga aattcgacac aattgtgctg ttagaaaatg
     5881 actctcagca tcctctatta tctgactaga atagggcagt gtacagataa gtgcagctac
     5941 taggctaatc ggtgaaaatc ctcgaataga agaagcggca aaaaaaatcg ataaaccttc
     6001 aattttataa ataccattga aagcaaggaa atttcctaaa ctcatgcaaa gaagggtcaa
     6061 aaataaagac atataaaacc gaggtgattg aacgactcgt acaagattac aaatgaaaaa
     6121 ttccatccca actcctcctt ataataaaaa tagggtgtag cattcttttt tcatgctaca
     6181 cccacaatca accatcttta aggcttactc tgacaagtaa gttaataaga atctgaactc
     6241 caagaacctg aagtatgaat tcttacatga tttccaaatt gtggcgccat agctaatcta
     6301 gtaccagaac caatataatt gtcaccacct ccattatagt acatgacaat cctagagcca
     6361 gaccccaatg aatataccgg ggtaatatct gacccactat aggcgctacg aatagaggta
     6421 tttaaccttt taccgccacc agtgctgtca ctattattaa ttccagcaga ggcgttttct
     6481 ttctcaagct cactagttgt atccgaaccc caacgcggca acgttaaatc ataatttcca
     6541 atctgtctag ctaaaactgt agggagaaac aaactagatg caattgtaac tacgcaaaaa
     6601 aggaatatat ttttcttctt ttcatgacat cgtcctctta agaagtgata aacaagatag
     6661 ttgattgatc aatttgatac atattacatt ttcattatat caataaaaga aagcgttgtc
     6721 aattatttta tttaaaatat tgtcatattt taaataaaat ggtaaaagag actcggtagc
     6781 ctcgtctctc tttatcttac tgacctaacc ttcttgccaa ttttcttggt cttctttaaa
     6841 gcgttttaga agatcaaggc cctctggcgt gatgtaacct tcttcttggg ctagatggat
     6901 aagctcgcta tagtttgaaa gcgtcacaag tttaacacca gcatctgcaa agttcttatc
     6961 tgcttttggc aattggtagc tgaaaatcgc tacaactcca agcacatctg ctccttctcg
     7021 cttggctgct gctacagctt caagaactga accacccgtt gaaataaggt cttcaaccac
     7081 taccattttt tgaccttgag ctacgcgacc ttcgatttga ttaccagctc catggtcttt
     7141 tggtttgcta cggatgtagg caaaaggcaa gtccatctta tcagcaataa tggctccgtg
     7201 tggaatccct gctgttgcag ttcctgcaat cacttctact tcaggaaagg cttctttgat
     7261 agcttccaca aaaccatttt caattagggt acgagtttct ggataggcta gtgtcacacg
     7321 attatcagtg taaatcggtg acttgatacc agatgcccaa gtgaagggtt cctctggttt
     7381 gaggtaaacg gcttggattt tcaagaggtg gctagcgata tctttagcaa gtgtcatggt
     7441 attctccttt tatttttcta atctagttct ttaattccag tcctgtgtcc attcatcctt
     7501 gatggcatga taagctgcaa caggatcctc agcttgggta atgggacgtc ccactacgat
     7561 atagtcactg ccgatttgat aggcatcagc aggtgtcatg actcgttttt gatctccaac
     7621 tgcaacacca gctggacgaa tccctggtgt cagacagata aaatctggat tggtagcctg
     7681 cttgatgact tgtacttcct gagccgagca aacaacacca tccaagccag cttcagctgt
     7741 cttcttggca tagtgaatca cagactcttg cagactggtt tggatatttt gaaactcctg
     7801 catctgagct tctgacgttg atgtgagctg cgttacagcg atcaatttgg cttgacttcc
     7861 aagaccttca cgcgcagcct tcatcatctc tacaccacca gccgcatgaa tattggtcat
     7921 atccacacca agctgagata ggatcttcat tgctgacttg actgtattag gaatgtcatg
     7981 aagtttgaga tccaaaaaga cactatgacc caaacctttt aagtaggaca caatctcagg
     8041 ccccgctgcg taataaagct ccatccctac cttgagataa aggctttctt ctgctgggaa
     8101 aagagctaaa aattccttga ccgcctcaaa actaggaaaa tcaagagcaa tgactggacg
     8161 atgttctcgc ataggtttct ccttttacct ttactagtga gagagtctgg ccaacagaag
     8221 ccacgaaaaa aggaacctgc caacagcaag gttccacgaa aaatgggtag tctccaccct
     8281 ttcaccgtct aaccttagct gcctctctgg actgctttaa aggttttcta ttattctatt
     8341 atttctacta gcacttgtca agtaaaaact tagtcacgta tgtgttgact gctattgaac
     8401 acctcacaag actctttcca aaagaatagt taaagacttt cacttaggac agagaaaaag
     8461 agtttgcttg ttacccttta attgaacaaa tgggaattct gttttatttt gcggatacct
     8521 attcatcttg gcaaagggga agtaatgaga atgcgaatgg acttcttcgt gagtattttc
     8581 ttaaaccgat ttggcaacaa ttaccgaaaa aatccttaat ggtgctttgc tagcttatta
     8641 atcaccgtcc ccaaaaatac ttggattaca agacaggttt tgaagcactt atagaggaga
     8701 tttaaaaatg ttgcattttt tattgcaatt tatcagttat cttatcaccc aaaacttctg
     8761 caattagtat gagcactatt gttatttttc ttttttcgta cactcaaatc aaaatatagc
     8821 aataagacta ttctgtagaa ttgctgtcaa aaagatcagt tcatttttcc ttcccacttg
     8881 tgtttataat cattaaaata actcaattaa gaaattttct ttttcctaat agttatcgta
     8941 attaaagtta atagaagaac aatccaaata agtagtgtta gattaggaat tagagtttta
     9001 ttccatgaaa atccctccca ttttgtgaaa aacttagtaa acagtcccat aaaactataa
     9061 tctgttatct tcgcaactgt cttatccaaa ccagatagca tcggtaagaa agcaactaaa
     9121 atcatagcag gaagactgat aacctgagct actacttggc tcttcgcggt taaacctatc
     9181 aataaataga ataaaatgat ggataaagag gttagaagaa cgattgtaat ataattaaaa
     9241 gtatgtacaa ttgtaactcc taaaataaga ggagtagttc ccataatcac aaaagttagc
     9301 aaaaaaggaa gaaacatcgt tgataaaatg tattcggatc ctttaacacc actcaacaga
     9361 agagtttgta aattgtactt ttctttttct tcagacaaga taatagttat aggacttcca
     9421 acagccaaag ccaaagaaaa aggtaaacac atcatcaaaa gaactaatgc ctgttgatcg
     9481 ttgaccttcc cctgtgtttc cataagatat ttataaaaat atgtgaaagc aaaaggcact
     9541 aaaacttgca ataaaatact cttattggaa aggatgattt gacaacgcaa ccataccaaa
     9601 gccagaaacc gtttaagcat ttagctttcc tcctgttaat gtgataaaaa tatcttctaa
     9661 agtaggctca catgaatgaa ttgaaaaaat attttccaga tcagcctgag atacctgttc
     9721 tagtgatgta aaatcaaaag ttatctgatt cccattataa tctgtaacct taatcttttt
     9781 atctttatta tatctttgaa tgagttcaga aggagctcct tgctcaacta atttcccttt
     9841 atttaataag gcaacataat cacataaaag acttgcttca ttcatatcat gagtcgttag
     9901 aaaaatcgtt gtccctgctg ttttcaattc taaaattaac tcatgaattg ttcgagaagt
     9961 tgtgggatct agacctgagg tcggttcatc cagaaagagt acagcgggtt tgttgataag
    10021 agctcgtgct aaaagcattc gttgcctcat tccagtggat aattttcctg ctaccatctt
    10081 gcgactatca tataatccta ctcgctttaa caaattatca acacgtaatt tactaatatt
    10141 ataaaattta ctataaaaaa gaagattgtt atacagagac attttctcat aaaatccact
    10201 tgtatcgcta accaatccaa ttctctttaa ttcaccgctt gttaaatttt gagatttttg
    10261 tcccaaaata atagattgtc ctttatcggc aaggaactgc ccagtcagaa tattaatcgt
    10321 tgtggtcttt ccagaaccag atggtcctaa aaatccaaaa atctaacctt ctttaacagt
    10381 gaagcttata ttatttaaag ctattttatc accaaaactt tttgataaat ggctaacttc
    10441 aatcatactc attgcacctc ctttatattc tacattttta cttaacatct atttacttat
    10501 ctttatcaaa taaacgtctt aaaaaaaaca ataacattaa gcatataacc gttagcaaga
    10561 ttgtttcaat attattga
//
LOCUS       DAVMBH010000064         9831 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVMBH010000064 DAVMBH010000000
VERSION     DAVMBH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.064"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            206..2134
                     /gene="glgB"
                     /locus_tag="VYP30_001888"
     CDS             206..2134
                     /gene="glgB"
                     /locus_tag="VYP30_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1808825.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVIMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2124..3266
                     /locus_tag="VYP30_001889"
     CDS             2124..3266
                     /locus_tag="VYP30_001889"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1808826.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3256..4395
                     /gene="glgD"
                     /locus_tag="VYP30_001890"
     CDS             3256..4395
                     /gene="glgD"
                     /locus_tag="VYP30_001890"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1808827.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4392..5825
                     /gene="glgA"
                     /locus_tag="VYP30_001891"
     CDS             4392..5825
                     /gene="glgA"
                     /locus_tag="VYP30_001891"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1808828.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5884..6255
                     /locus_tag="VYP30_001892"
     CDS             5884..6255
                     /locus_tag="VYP30_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1808829.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6200..6424
                     /locus_tag="VYP30_001893"
     CDS             6200..6424
                     /locus_tag="VYP30_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1808830.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            6538..7653
                     /locus_tag="VYP30_001894"
     CDS             6538..7653
                     /locus_tag="VYP30_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1808831.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLEHTAANIRRLLSLSKI"
     gene            complement(7650..8096)
                     /locus_tag="VYP30_001895"
     CDS             complement(7650..8096)
                     /locus_tag="VYP30_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEV1808832.1"
                     /translation="MTDLSKQLLEQAHGGAKLNPDEQRRYLGTFEERVLGYADIDTAN
                     SPQLEKGFLSILEKLQEKADPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHTS
                     SPFGLIIHSNAPVQVEEKNLRLAFPKLWEGKKEEPAKTSIWKKWFS"
     gene            8260..9564
                     /gene="eno"
                     /locus_tag="VYP30_001896"
     CDS             8260..9564
                     /gene="eno"
                     /locus_tag="VYP30_001896"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1808833.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAIATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9702..>9831)
                     /locus_tag="VYP30_001897"
     CDS             complement(9702..>9831)
                     /locus_tag="VYP30_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HEV1808834.1"
                     /translation="KTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
BASE COUNT         2942 a         1751 c         2176 g         2962 t
ORIGIN      
        1 cctgttatta tttcatttca ctatagtaga aaaagaaagg cgttttcgca attttttgaa
       61 aaaatattga tttacaattg aacgagtaag tgaacttgtt gtagattttc aaaataatta
      121 aagaagtata gtaatttact tgaatcttct ctaaaaaggt agtataataa aaacacagaa
      181 aacgcttaca ggagaagggg agtatatgga taatagagaa gcattaaaaa cctttatgac
      241 gggtgaaaat ttttatctcc aacattatct aggagcacat agggaagaac taaatggaga
      301 gcatggctat accttccgtg tttgggcacc taatgctcag gctgttcact tggttggtga
      361 ttttaccaac tggattgaaa atcagattcc aatggtaaga aatgattttg gggtctggga
      421 agtctttacc aatatggctc aagaagggca tatttacaaa tatcatgtca cacgtcaaaa
      481 tggtcatcaa ctgatgaaga ttgacccttt tgctgtcagg tatgaggctc gtccaggaac
      541 aggggcaatc ttaacagagc ttcctgagaa gaaatggaag gatggacttt ggctggcacg
      601 aagaaaacgt tggggctttg aagagcgtcc tgtcaatatt tatgaagttc acgctggatc
      661 atggaaaaga aattctgatg gcagtcctta tagttttgcc cagctcaagg atgaactcat
      721 tccttatctc gttgaaatga actatactca tattgagttt atgcccttga tgtcccatcc
      781 tttgggcttg agttgggggt atcagcttat gggttacttc gctttagagc atgcttatgg
      841 ccgaccagag gagtttcaag attttgtcga ggagtgtcat acccataata ttggggttat
      901 tgtggactgg gtaccaggtc actttaccat caacgatgat gccttagcct attatgatgg
      961 gacaccgact tttgaatacc aagaccataa taaggctcat aaccatggtt ggggtgccct
     1021 taattttgac cttggaaaaa atgaagtcca gtccttctta atttcttgca ttaagcattg
     1081 gattgatgtc tatcatttgg atggtattcg tgtggatgct gttagcaaca tgctctattt
     1141 ggactatgat gatgctccat ggacacctaa taaagatggc ggaaatctca actatgaagg
     1201 ttattatttc cttcagcgct tgaatgaggt tattaagtta gaatatccag atgtgataat
     1261 gattgcagaa gaaagttcgt ctgcgaccaa gattacggga atgaaagaga ttggtggtct
     1321 aggatttgac tacaaatgga acatgggctg gatgaatgat atcctccgtt tctacgaaga
     1381 agatccgatc tatcgtaaat atgactttaa cctggtgact ttcagcttta tgtatgtttt
     1441 caaggagaat tatctcttgc cattctcgca cgatgaagtg gttcatggca agaagagtat
     1501 gatgcataag atgtggggag atcgttacaa tcaattcgca ggcttgcgca atctctatac
     1561 gtaccaaatt tgtcaccctg gtaagaaatt gctcttcatg ggtagcgaat acggtcaatt
     1621 cctagaatgg aaatctgaag aacagttgga atggtctaac ctagaagacc caatgaatgc
     1681 taagatgaag tatttcactt ctcagctaaa ccagttttac aaagatcatc gctgtctgtg
     1741 ggaaatcgat accagctatg atggtattga agtcattgat gcggataatc gagaccagag
     1801 tgttctttcc tttattcgta agggtaaaaa gggagaaatg ttagtctgta tctttaacat
     1861 ggtacctgtt gagcggaaag attttacaat cggactaccc gttgcaggaa tttacgaaga
     1921 agtatggaat actgagttgg aagagtgggg aggcgtttgg aaagaacata atcaaactgt
     1981 tcaaacgcaa gaaggactat ggaaagatta tgagcagacc ttaaccttta ccctaccggc
     2041 tatgggagca agtgtatgga aaatcaaacg tcgcttgaaa tctactaaaa ccgtcacaaa
     2101 taaaaaccaa aaaggagtag aaaatgaaaa atgaaatgtt agctttgatt cttgctggtg
     2161 ggcaaggaac tcgtctcggt aaactcactc aaagcatcgc aaaaccagct gtgcaatttg
     2221 gtgggcgcta ccgtatcatt gactttgccc tatcaaactg tgccaactca gggattcata
     2281 atgttggggt cgttacacag tatcaaccac ttgctctcaa caaccatatt gggaatggtt
     2341 caagctgggg actagacggt attaattcag gtgtctctat tcttcaacct tattctgcaa
     2401 gtgaaggaaa tcgttggttt gaggggacta gtcacgctat ttaccaaaat atcgactata
     2461 tcgacagtgt caatcctgag tatgtcttga ttttgtctgg ggatcacatc tacaaaatgg
     2521 actatgatga tatgctccag tctcataagg ataataatgc cagcttgaca gtagcagttt
     2581 tagacgtccc tcttaaagaa gcaagccgtt ttggtatcat gaacacagat gctaacaatc
     2641 gtattgttga atttgaagaa aaaccagctc aacctaaatc tacaaaagct tctatgggaa
     2701 tctacatttt tgattggcaa cgccttcgta atatgttagt cgctgctgaa aagagcaagg
     2761 ttggcatgtc agactttggt aaaaatgtca ttccaaatta ccttgagtca ggtgaaagtg
     2821 tttatgctta cgaatttagt ggttattgga aagatgttgg tactattgag tcactttggg
     2881 aagcgaacat ggagtatatt tctccagaaa atgccttgga tagtcgtaac cgtcaatgga
     2941 agatttactc aagaaacttg atttcaccac caaacttcct cggggcaaat gctcatgtgg
     3001 aagactcatt agttgtagac ggatgtttcg ttgatggaac tgttaaacat tctatccttt
     3061 caacaggcgc gcaagttcgc gaaggagcgg aagtccttga ttcagttatc atgagtggag
     3121 ctatcattgg tcaaggagct aagattaaac gtgccattat tggtgaaggt gcgattattt
     3181 ctgacggtgt cgaaattgat ggaacagatg aagtacaagt tgtaggatat aatgaagtag
     3241 tgggggtagc aacagatgaa gattgataaa tattctgcca ttttaggaaa tacagttggt
     3301 tttcacaata tgtcgacatt gacggaccac cgtccagtag caagtttgcc atttggtggg
     3361 aaatatcgtt tgattgactt cccactttca agccttgcta atgcaggtgt tcgtagtgtc
     3421 tttggtattt tccagcagga taatatcagc tcagtatttg accatattcg ttcaggacgc
     3481 gagtggggct tatcaaccct tcttagccat tactatctag gaatttacaa tacccgtgta
     3541 gaaagtagta cagttggaaa agaatactac caacagcttc ttacttattt gaaacgttct
     3601 ggctcaaacc aaacggttgc cctcaactgc gatgttctta ttaacattga tttgaaccaa
     3661 gttttccacc tacatagtac aacaaaagag cctatcactg tagtttataa aaaactagct
     3721 aagaaagata tttcagaagt aaatgcaatc ttggatgtag atgaaacaga ccatgttctt
     3781 tctcataaac tctttgatag caagtcaaca gctgaaacgt tcaatatgtc tacagatatc
     3841 tttgtcgttg atacaccttg gttgattgaa cacttggaag aagaagctaa aaaagaacat
     3901 ccagagaaat tgcgctatgt tttacgggat ttggctgtaa aagagggagc tttcgcctac
     3961 gagtacacgg gctatctagc caatattcac tctgttaaat cttattatca agcgaatatc
     4021 gatatgcttg aatcacaaaa attctattct cttttctcac caaaccaaaa gatttataca
     4081 aaggtcaaaa acgaagagcc aacttactat gctaatacat ctaaggtaag aacttctcag
     4141 tttgcctctg gtagtattat tgaaggtcaa gtagctaatt ctgttctatc acgtaatatc
     4201 catgtccata aggatagctt ggttaaagat agcctgctct tccctcgtgt tgttattgga
     4261 gaaggggctc aggtcgaata tgctatcttg gacaaagggg ttgaagttga gcctggtgtt
     4321 gtgattcgag gaactgcaga acatccagtt gtggttaaga aaggtgctaa agtaacagag
     4381 gatattcatt catgaaaatt ttatttgtag cagcagaggg tgcacccttt tcaaaaacag
     4441 gtggtttggg agacgtcatt ggcgctcttc caaaatcact ggtaaaagct gggcacgaag
     4501 ttgcagtgat tttaccctac tatgatatgg tagaggctaa atttggaaat cagattgaag
     4561 atgtgcttca ttttgaggtg agcgttggtt ggcgcagaca gtattgtgga attaagaaaa
     4621 cagtattaaa tggtgtaacc ttctacttta ttgacaatca atattatttc ttccgtggtc
     4681 atgtttacgg tgattttgat gacggagaac gctttgcctt tttccaactg gctgccattg
     4741 aggctatgga aaggattgac tttattcctg atcttctcca tgttcatgac taccatacag
     4801 ctatgattcc tttcttgttg aaggaaaaat accgttggat tcaagcctat gaggacattg
     4861 aaacagtttt aaccattcat aatttagaat tccaaggaca attttcagaa ggaatgttgg
     4921 gtgatttgtt tggagttggc tttgaacgtt acgctgatgg cacccttcga tggaacaact
     4981 gtctgaactg gatgaaggca ggtattctct atgcgaaccg tgtttcaacc gtttcaccta
     5041 gctatgctca tgaaattatg actagtcagt ttggatgtaa tttggatcag attcttaaaa
     5101 tggagtctgg taaagtatct ggtatcgtga atgggattga tgctgatctt tataatcctc
     5161 agacggatgc tcttttagac tatcatttca atcaggaaga tttgtctggg aaagccaaaa
     5221 ataaggcaaa attgcaagaa agagttggct tgcctgttag agcagacgtt ccactggtgg
     5281 gaattgtttc tcgtttgaca cgtcaaaaag gttttgatgt ggtggtcgaa agtcttcacc
     5341 atatcttgca agaagatgtt cagattgttc ttttgggaac tggcgatcca gcctttgaag
     5401 gagctttctc atggtttgct cagatttacc cagacaagct atcaacaaat atcacttttg
     5461 atgtcaaact tgctcaggaa atctacgctg cttgtgacct cttcctcatg ccaagtcgtt
     5521 ttgaaccgtg tggcttgtct caaatgatgg ctatgcgtta tggaaccttg ccattggtcc
     5581 atgaagttgg aggcttgcga gatacagttc gcgctttcaa tccaatcgaa ggaagcggta
     5641 ctggctttag ctttgacaat ctatctcctt attggttaaa ttggactttc caaacagcat
     5701 tggacttgta tagaaaccat ccagacattt ggagaaacct acaaaaacaa gctatggaga
     5761 gtgacttctc atgggataca gcctgcaagt cataccttga cttgtaccat agtttagtta
     5821 attaatagat aaaatcgtat gatgacttca tacgattttt aggctgttta gagaggagaa
     5881 ctgatgtctc aagtaaaagg cttgtgtgtt ttggatgtag atggaacctt aatcctagaa
     5941 gaagtgattg atcttttagg gagagaggca ggtcatgagg cggaaatttc gcagattaca
     6001 agtcgagcaa tgcgaggaga gttggtcttt gaaagcagtt taagaaaaag agtgtccttg
     6061 ttggaaggtc ttcctatttt ggtctttgat aacgtcttca actcaattca tctatcgcta
     6121 aatgtcccag agttcatctc tattctccaa aagaatggca tcctagttgg tctggtgtct
     6181 ggtggattta caccaatagt tggagagatt agcaaaatcc cttggtattg cctatttcac
     6241 tgccaaccag cttgaagtca aagaaggtct tttaacagga aaattagttg gacaaattat
     6301 aagtccccag gtcaaaaaag aaactctgga aaaatggaga aagaaactaa aactttctaa
     6361 agaaagaacg gtggcaatcg gtgatggggt caataatcta ttaatgttga agtcggcgga
     6421 gtgaggaatc gccttttgtt ccaaagaaat gctcaaaaaa gaaataccac atcatgttga
     6481 caagagggat tttttagaag ttcttccttt gattgactgt ttagaatgag ggaaaatatg
     6541 aagattgtaa ttgcaccgga ttcgtttaag gaaagcttga cagctcaaca ggtagctgaa
     6601 gcaataaaaa gaggcttcca acaatcgata gcagatgtag aatgtctcct ctgccctgtt
     6661 ggtgatgggg gagaaggtac tgtagatgct atccgacatt ctcttgacct aaaagaaaaa
     6721 tggatccaag tgacagaccc ttttggacaa aaagaagcca tgcgctattt tcaaaaaggg
     6781 gaactggcac tatttgaagt agctgacttg gttggtcttg gaaaaattcc gctagagaaa
     6841 cgaaatccac ttcaaatcca aacttgtggt attggagagt tgattctcca tctcatttct
     6901 aaagggatta aagatattta tatcggtgtt ggtggcacgg ccagtaatga tggaggactg
     6961 gggattgctg ctggtttagg ttatcaattt tatgataggg atggaaatgt cttgcctgct
     7021 tccggtcaat ccttattaaa cttagcttct gtttcaacag aaaattgcta taaaattcct
     7081 gaaggtgttc aaattcatat tttagcagat gtcgtgagtc ccttatgtgg tcatcaaggt
     7141 gcgacttaca cttttggcaa tcaaaaaggt ctacatccga ctatgtttgc agtcgtagat
     7201 caggcgatcc aagattttta tgaaaaattc tcacctgcaa cattagaaat taaaggagca
     7261 ggagcaggtg gaggccttgc tggtggtttg tgtgcctttg ctcaggcaag tatcgtgtct
     7321 ggaattgata cctgcttgga cttaatcaac tttgataaga aagtttcaga tgctgacttg
     7381 gttgttgttg gagaaggaag acttgatagt caaagctttg ctgggaaagc gcctataggt
     7441 gttgcaaaaa gaacccctgt tggagttcct gttattgcta tttgcggtag tcttgctgaa
     7501 gatttacctc ccctaccatt tgaaaatatc caagctgtct tttctatttt ggagaaaagt
     7561 gaacctttag aagatagttt gaaaaatgcc agtctctatt tggagcacac ggctgccaat
     7621 attaggcgtt tattaagtct gagtaagatt tagctaaacc atttcttcca gatggatgtt
     7681 ttggcaggtt cttccttttt accttcccaa agttttggaa aagcaagtcg aaggttcttt
     7741 tcttctactt gtactggtgc attgctatgg ataatcagac cgaaaggaga agaagtatgt
     7801 tcctcagata ctatggtagc ttgactatcg gtttctttgg cttccttcaa gtagaaaact
     7861 tgcttgtcaa attcgatagt tggtgaaatc ttcacaaata gtggatctgc tttttcctga
     7921 agtttttcta aaatagataa aaagcctttt tctaactgag gactatttgc tgtgtcaata
     7981 tctgcatatc caagaactct ttcctcaaaa gtaccaagat agcgtctttg ctcatccgga
     8041 tttaattttg ctccaccatg agcttgttca agtaattgtt ttgataaatc tgtcatgaaa
     8101 acagtatatc ataaaagtta gaataaaaca gacaaaagaa agcgattact ttataaagtt
     8161 aaggaaaagt tgcacaaaga taacgttttt tcttgaaaaa ggaggggttt taaggtatta
     8221 tagaggtgta aaaaatttaa ctcataagga gagtaaaaaa tgtcaattat tactgatgtt
     8281 tacgctcgcg aagtcctaga ctcacgcggt aacccaacac ttgaagtaga agtttacact
     8341 gaatcaggtg ctttcggacg tggtatggtt ccatcaggag cttctactgg tgaacacgaa
     8401 gcagttgaac ttcgcgacgg tgacaaatct cgttacggtg gtcttggtac acaaaaagct
     8461 gttgacaacg taaacaacat cattgctgaa gctatcattg gctacgatgt acgtgatcaa
     8521 caagctatcg accgtgctat gatcgctctt gacggtactc ctaacaaagg taaattgggt
     8581 gcaaacgcaa tccttggtgt gtctatcgct gtagctcgtg ctgctgctga ctaccttgaa
     8641 atcccacttt acagctacct tggtggattc aacactaaag ttcttccaac tccaatgatg
     8701 aacatcatca acggtggttc tcactctgac gctccaatcg ctttccaaga gttcatgatc
     8761 ttgccagttg gtgcgccaac atttaaagaa gcccttcgtt acggtgctga aatcttccac
     8821 gctcttaaga aaatccttaa atcacgtggt ttggaaactg ccgtaggtga cgaaggtggg
     8881 ttcgctcctc gtttcgaagg aactgaagat ggtgttgaaa ctatccttgc tgcgattgaa
     8941 gctgctggat atgtaccagg taaagacgta tttatcggat ttgactgtgc ttcatcagaa
     9001 ttctacgata aagaacgtaa agtttacgac tacactaaat ttgaaggtga aggtgctgct
     9061 gttcgtacat ctgcagaaca aatcgactac cttgaagaat tggttaacaa atacccaatc
     9121 atcactattg aagatggtat ggatgaaaac gactgggatg gttggaaagc tcttactgaa
     9181 cgtcttggta agaaagtaca acttgttggt gacgacttct tcgtaacaaa cactgactac
     9241 cttgcacgtg gtatccaaga aggtgctgct aactcaatcc ttatcaaagt taaccaaatc
     9301 ggtactctta ctgaaacttt tgaagctatc gaaatggcta aagaagctgg ttacactgct
     9361 gttgtatcac accgttcagg tgaaactgaa gattcaacaa tcgctgatat tgcaattgca
     9421 actaacgcag gacaaatcaa gactggttca ctttcacgta cagaccgcat cgctaaatac
     9481 aaccaattgc ttcgtatcga agaccaactt ggtgaagtag ctgaatatcg tggattgaaa
     9541 tcattctaca accttaaaaa ataaaatagt tcagtgaact attttatccc gaaccatgaa
     9601 attcaaaagt tcggccgttg atttaacaac gtttctagcc cctcggattt tatccgaagg
     9661 gctatttttg tatttagagg acaaaaaagg gacaaaactt tttaaaaaat ctttttcata
     9721 actttatcca gtacattgat tgcttcatct ttcatgttct ttgtgacgtg ggtgtagatg
     9781 gaagtagtga cttcagagtc ggaatgacca accctgtccg tgattgtttt t
//
LOCUS       DAVMBH010000065         9500 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVMBH010000065 DAVMBH010000000
VERSION     DAVMBH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.065"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            545..1084
                     /locus_tag="VYP30_001898"
     CDS             545..1084
                     /locus_tag="VYP30_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808835.1"
                     /translation="MNSKKIVPKTKTHTFDDVIEQGYCHRLSRYVPDAVVGGSYKYDS
                     TDALPYAKKLKNTLYGQNLSVKYVASLLDMWDRACQLFHTVTGTCLADDIFTSKKIYS
                     ELYFYNTNTSDFITDEIIELVKEKHRSYSRKADEDSILSVEHEFEINPDIYYYVLGKL
                     GWKRVKHNYLVKALAGALS"
     gene            1143..1373
                     /locus_tag="VYP30_001899"
     CDS             1143..1373
                     /locus_tag="VYP30_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808836.1"
                     /translation="MKNLYKYLFYLFFIGFGCTLYYVLLLKNVYSPIFEAIAILMGIT
                     MIIFLMIFIDMASPAGEERKHENVESKNLGDE"
     gene            1336..2697
                     /locus_tag="VYP30_001900"
     CDS             1336..2697
                     /locus_tag="VYP30_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1808837.1"
                     /translation="MRMLNQRISVMNKYPYFIRPRNIKIVRLAIQIFTLLLLMCSWIA
                     TIPFIARLVFSMFFISLLFLVERFFRSNFMANLRDKLNIREALFYMLISLNLYDEIDN
                     EVVDTAVLYFDVEDNKVIVCVPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKTI
                     YVLGHVVQIEQYVFNSNTLKREFFEDIPNPIIKLSNTQQFSLKSNTNIGIYGRTGTGK
                     TIALQWYLFNALAKGCGTNDNTYLGIVDGKAADLFALGKLLQEDLGEQIAVGSSPQML
                     AKLSREFVEIMNERFEIIKQNSSLNADAYDLGMTPNFLFVDELASIRDSCGSSKQGGK
                     ELWNEILQNLGLIARKGRQAGCHLCLSTQDPNAENIPVELRSQISAVLYLGGPGADRL
                     KMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKQEFLQVVRNIL
                     PNY"
     gene            2795..3109
                     /locus_tag="VYP30_001901"
     CDS             2795..3109
                     /locus_tag="VYP30_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808838.1"
                     /translation="MKLNDFLKPELLGNRFFAVKGYTEVLDRETNKPVALRLNVSIQD
                     ENSDFFMEMIQVKINTLSPTASVQEMANNKTCPVSLKDLNVGQFNGNLWFACSDVLPV
                     TK"
     gene            3143..3532
                     /locus_tag="VYP30_001902"
     CDS             3143..3532
                     /locus_tag="VYP30_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808839.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKDLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            3699..4472
                     /locus_tag="VYP30_001903"
     CDS             3699..4472
                     /locus_tag="VYP30_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1808840.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYDWKIEKELNSIEVINLMGNHDVYYLLGEQVPFSIQNLEVFFSV
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLLFDPKEWHFKPFTEEYEEELEILANAVGYMR
                     GGGDMAGSPLWAHFRELELIPNHNYPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYVQGHLEIFSTDWATDQTLKQLPKPQI"
     gene            4656..5438
                     /locus_tag="VYP30_001904"
     CDS             4656..5438
                     /locus_tag="VYP30_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV1808841.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTDTKSKEKSQR
                     RTFDELTPEEQEQRLERMKKTRLEAKWNLLRLVDCNYNDNTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYLTVLEKQKRGAWHAHILLFSVPYVPHRQLLELW
                     GHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDRFY
                     TYEDFNYDSSVVLYETEYISKVYKDGQYFDNHVKYKKIKLDE"
     gene            5452..5655
                     /locus_tag="VYP30_001905"
     CDS             5452..5655
                     /locus_tag="VYP30_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV1808842.1"
                     /translation="MIATVTKNDLVALGFSEGTSKHIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLGFDVQNSTLKE"
     gene            5659..6791
                     /locus_tag="VYP30_001906"
                     /pseudo
     CDS             5659..6791
                     /locus_tag="VYP30_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            6832..7269
                     /locus_tag="VYP30_001907"
     CDS             6832..7269
                     /locus_tag="VYP30_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HEV1808843.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPEIVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            7485..7721
                     /locus_tag="VYP30_001908"
     CDS             7485..7721
                     /locus_tag="VYP30_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV1808844.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWGECGKKAISHEEMMRRYG"
     gene            7714..8445
                     /locus_tag="VYP30_001909"
     CDS             7714..8445
                     /locus_tag="VYP30_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1808845.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(8556..8639)
                     /locus_tag="VYP30_001910"
     tRNA            complement(8556..8639)
                     /locus_tag="VYP30_001910"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8603..8605),aa:Leu,seq:caa)
     gene            complement(8649..8720)
                     /locus_tag="VYP30_001911"
     tRNA            complement(8649..8720)
                     /locus_tag="VYP30_001911"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8686..8688),aa:Gln,seq:ttg)
     gene            complement(8731..8803)
                     /locus_tag="VYP30_001912"
     tRNA            complement(8731..8803)
                     /locus_tag="VYP30_001912"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8768..8770),aa:His,seq:gtg)
     gene            complement(8818..8888)
                     /locus_tag="VYP30_001913"
     tRNA            complement(8818..8888)
                     /locus_tag="VYP30_001913"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8854..8856),aa:Trp,seq:cca)
     gene            complement(8893..8973)
                     /locus_tag="VYP30_001914"
     tRNA            complement(8893..8973)
                     /locus_tag="VYP30_001914"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8937..8939),aa:Tyr,seq:gta)
     gene            complement(8986..9058)
                     /locus_tag="VYP30_001915"
     tRNA            complement(8986..9058)
                     /locus_tag="VYP30_001915"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9023..9025),aa:Phe,seq:gaa)
     gene            complement(9062..9135)
                     /locus_tag="VYP30_001916"
     tRNA            complement(9062..9135)
                     /locus_tag="VYP30_001916"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9099..9101),aa:Met,seq:cat)
     gene            complement(9146..9235)
                     /locus_tag="VYP30_001917"
     tRNA            complement(9146..9235)
                     /locus_tag="VYP30_001917"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9197..9199),aa:Ser,seq:tga)
     gene            complement(9318..9391)
                     /locus_tag="VYP30_001918"
     tRNA            complement(9318..9391)
                     /locus_tag="VYP30_001918"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9355..9357),aa:Ile,seq:gat)
     gene            complement(9426..9496)
                     /locus_tag="VYP30_001919"
     tRNA            complement(9426..9496)
                     /locus_tag="VYP30_001919"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9462..9464),aa:Gly,seq:tcc)
BASE COUNT         3404 a         1582 c         1681 g         2833 t
ORIGIN      
        1 tattagtgac aatgttttat aaacttgtgt cattcttctt tctactacaa taacaaaatt
       61 atttgcttta tctactgttg tcatattgtt cctccatcta accattatag catcgcaaat
      121 cttttttgtc tactttttta aaataaacgg tctatttaaa aatattagac aaaaagaccg
      181 tatttttctt gacatagtgg atacgatatg ctaagatatc atcaacaggt aaataattac
      241 ctcaaacacc gtgtagaaag gaaaatttgt catgacccca gaagaacaaa tggcattaga
      301 gtatttttat gaagagatgg acgcctatta ttgtgaggaa gaacaaggag agatttttga
      361 ttgatacgag aattaaatca tatctatagt ttctcaggat aattggaaac tatatttgca
      421 agatactaca tttatacaca aaacacaaaa aggagaagat aaatgaatat tgcaagagcc
      481 tcacccagag tagagactaa ttgaaacaat gatacatata ttaattttga aaggaaatat
      541 tgttatgaat tcaaaaaaaa tagttccaaa aactaaaact catacctttg acgatgttat
      601 cgaacaaggg tattgtcata ggctatcaag atatgttcct gatgcagttg ttggaggttc
      661 ctacaaatat gattcaacag atgcattacc atatgcgaaa aaacttaaaa atacactata
      721 tgggcaaaat ttatctgtta agtatgtagc aagtttgttg gatatgtggg atagagcatg
      781 tcagttattt catacggtaa cagggacatg cttagcggat gacatcttta cctcaaagaa
      841 aatttatagt gaattgtatt tttacaatac taatacttct gattttatta cagatgagat
      901 tattgaactt gttaaagaaa aacatcgttc atattctaga aaagctgatg aagatagcat
      961 tttatcagtt gagcatgagt ttgagattaa ccctgacatc tattattatg ttctaggcaa
     1021 attgggttgg aaaagagtaa aacacaatta cctagttaag gctcttgcag gggcattatc
     1081 ttagtttaat ctaggggagt attcctcccc ttttatatct taaaaaagaa aggaattgcg
     1141 tcatgaagaa tctctataaa tatctttttt atttgttctt tattggattt ggttgcacat
     1201 tatattatgt gcttctttta aaaaatgtct attctcctat ctttgaagct attgcaatat
     1261 tgatgggtat tacgatgatt atctttttga tgatttttat agatatggct tcccctgctg
     1321 gagaggagag aaaacatgag aatgttgaat caaagaatct cggtgatgaa taagtatccg
     1381 tactttattc gtcctcgaaa tattaaaatt gttagactag ctattcaaat ttttaccctt
     1441 ttacttctca tgtgttcatg gattgctaca atcccattta ttgcacgtct agtcttttcc
     1501 atgtttttta taagtcttct ttttttagta gagaggttct ttcgttctaa ttttatggca
     1561 aatttaagag ataaactcaa tatcagagaa gcattgtttt atatgctaat tagtttaaat
     1621 ttgtatgatg aaatagataa tgaagtagta gatacagcag ttctatattt tgacgttgag
     1681 gataataaag ttattgtctg tgtcccacta tttgggaatc gttatctgaa aaccttgaaa
     1741 aatttagagg aatatctatg ccctacgttg ggcttgtcct tgctgtctaa aaaagaagaa
     1801 atagacaaaa caatatatgt gttaggtcac gtagttcaaa ttgagcaata cgtcttcaat
     1861 agtaatacat taaaaagaga attttttgaa gatattccta atccgataat taaattatct
     1921 aacacccagc aattcagctt gaaatcaaac accaacatag gtatatatgg acgaactgga
     1981 acaggcaaaa caatagcctt acaatggtac ttatttaatg cactagctaa aggttgtggc
     2041 actaatgata atacttacct aggaatagtg gacggtaagg cagcggattt atttgcactt
     2101 ggaaaacttc tccaagaaga cttaggggag caaatagcag tcggctcttc acctcaaatg
     2161 ttagcaaaat tatcaagaga atttgttgag attatgaatg aacgttttga aattatcaaa
     2221 cagaatagtt cattaaatgc tgatgcttat gatttaggga tgacaccaaa ttttctattt
     2281 gtagatgaac ttgcttccat ccgcgatagc tgtggttcta gcaaacaggg gggtaaagaa
     2341 ctatggaatg aaattttgca aaacttaggc ttgattgcac gtaaagggcg gcaggcaggt
     2401 tgtcacctct gccttagtac ccaagaccct aatgctgaga atattccagt cgaattgcgc
     2461 tcccaaatat cggcagtttt ataccttgga ggcccagggg ctgatagatt gaagatggct
     2521 tttagcatgt gcgaattaga aaacgttcct acagtttcag atagaaaagg ggaggctctc
     2581 ttttatgctg atgggcttaa tacagtagag ccagtgctaa caattgtgcc atttgttgat
     2641 ttaaaaacta aacaagaatt tttacaggta gttagaaata tactgccaaa ctactaataa
     2701 cggtattttt ctctgttgga ataggaattc ttttcaacag agaaaaagag ccaaccgact
     2761 gcattgcagg aggtaagaaa gaaaggaatt tatcatgaaa ttaaatgatt ttttaaaacc
     2821 tgagctacta ggcaatcgct tctttgccgt gaaagggtat acagaagtat tagatagaga
     2881 gactaataag cccgtagctt tacgacttaa tgtgtcaatt caagatgaga attctgattt
     2941 ctttatggag atgatacaag tcaaaataaa tacattatcg cctactgctt ctgttcaaga
     3001 gatggcgaac aacaaaactt gtcctgttag tcttaaagat ttaaacgtag ggcaattcaa
     3061 tggaaatttg tggttcgctt gttctgatgt tttacctgta acaaaatagc taagattaga
     3121 taatatataa aggagtttta caatgcaaac ttttaactac gatgatttta agaatgaaaa
     3181 ggggattgtt tcattttctg aagcagaaca aatctattct agtctcctta attcctccaa
     3241 tcaacttgat aaagaatttc aagaagaatg gacaacattt gtacttctat gcgtagagta
     3301 tgcctctgca cgtggtaaat ggctcacact ctcaagagaa gagaaacttg ccaatgatga
     3361 atctagaact gttactcaca ataaagttat ttatcaacta aagattttaa aagatttagc
     3421 aagtgaacag ggcaatgatg ttgcttggtt tgaacaattt aacgatgaca gaaaacgtat
     3481 tggcgacttt gcttgctatg tagcttatat ctatgcctta aatgctcgat agacaattag
     3541 aggatattat agctatatat tactctatgt ctgatattca tggaaattat taaataacat
     3601 cttaagaata attaattcta tttatctatc accgaaacaa tgtgctataa cttaattcga
     3661 ttcttagact aatatcaaaa ataaagaggg gaatatatat gaagacgtta ttaattggtg
     3721 atttacactt aaaatctcaa ctgattttac ccattgttga caaaattatc caaacacata
     3781 atattaagag aatcattttt cttggtgatt atgttgattt acatggacaa actaacaata
     3841 tccaactata tgccaaagac ctcacttttc tatacgattg gaaaatagaa aaagaattaa
     3901 attcaataga agttattaac cttatgggca atcacgatgt ttattattta cttggagaac
     3961 aagttccttt ctcaattcaa aatctagagg tctttttctc agttcaacaa ttattacaag
     4021 atttgaattt acaagtagct tatcaactag atgattattt agttagccat gctggtttca
     4081 atttgctatt tgacccaaaa gaatggcact ttaaaccttt tactgaagaa tatgaagaag
     4141 aattagaaat ccttgctaat gcagtaggat atatgcgtgg aggaggagat atggctggtt
     4201 ctcctttatg ggctcatttt agagaactag agctaatccc taatcacaac taccctaaac
     4261 aaattgttgg acatacccct aaagaatcta tcgatatttc taaaaatgtt attggtatag
     4321 atactttttc attatatatt gacaaagata ataaatatca atttattggt aacggagatt
     4381 tgctcgttta tgtccaagga catcttgaaa tcttttcaac tgactgggct acagaccaaa
     4441 cattaaaaca attacctaaa cctcaaattt aactactact tctcatcatg tgactaagcg
     4501 aaactgccga ctggaagtcg gcaagctgga agcgtgttta gcagagcgat gcttagaaac
     4561 acatgataga agtatggagg agctttgctt ctcctagttt atttattata tagacaatct
     4621 tttggcgaaa gccaacctaa aaggaactat tttttatgac ctcgtataat aaaaaaatag
     4681 tccgcacttc ttcctatatt gaaatttggg aatatgaaaa accaatattt tcaaaaggaa
     4741 aatccatttt agatactgat actaaaagca aggaaaaatc acaacgtaga acatttgatg
     4801 aacttacacc tgaagaacaa gaacaacgtc tggagcgtat gaaaaaaact cgcttagaag
     4861 caaagtggaa cttacttcga ttagttgatt gtaattataa tgataatact tcatttctaa
     4921 ccctgaccac taaagaaaat attagcgaca gaaaccactt caaagactta ctaaaaactt
     4981 ttataaaacg ctttaactac cacatcttta ataccaagaa aagtaaatta aaatatttaa
     5041 cagtattaga aaagcaaaaa cgtggagcat ggcatgctca tattctgctt ttcagcgttc
     5101 cttatgtacc acaccgtcaa ctcttggaac tttggggaca tggagcagta cggataaata
     5161 aagttgatgt agacagcaaa gaaaatcgcg gtcgatatgt cacaaagtat tttgaaaaag
     5221 ggattggaca agaattgttg gaaaacttcg gaaagcaagc ctatttttca tcacgcaact
     5281 taaaaaagcc tgatgaagat agattttata cttatgaaga ttttaattat gatagttcag
     5341 tcgtactata tgaaacggaa tacattagta aagtctataa agacggtcag tatttcgata
     5401 atcatgtaaa gtataagaaa ataaaactag atgaataaag gagtaagtta catgatagca
     5461 actgttacta agaatgacct agttgccctt ggtttttctg agggcacatc taaacatatt
     5521 atccgccaag ggaaagagct actgataacc cgaggcttta cagtctatca gaacaagcga
     5581 attggtacta tacctgctac tattgctacc gaattactcg gttttgatgt tcaaaacagt
     5641 accctcaagg agtaaaatat ggcaattaga aaaggtaaag acggtaattg ggtagttgat
     5701 attagcaacg gttttgaccc aataacacta aagcaacgta gacttgtcag aaagggatat
     5761 atgacgaaaa aagaagctat tgaagcagaa cactacttac gaagtgtaga gttaaaagaa
     5821 cgcttctatg gggctaaaat aactatctcc atactatatg aactacttaa ggaagaagat
     5881 agcataaatc atcgaaaagc aagctatatc aatacacaag ataataatta caacaaacac
     5941 atcaaagatt atttttctat ggtcgataat gtcggaaact aacctatgaa gacatctacc
     6001 aatttagaga acatcttagg caaaaagtag ctaaaaattc tgataaaccg ttaagcacaa
     6061 atactattaa caaaatcatg attttactca aaaaaatttt tgatgttggt ttgcgaaaag
     6121 gctattactc ctccaatcca gcaaaattga taaaaaagtt gccaattgaa aaaacaaaaa
     6181 tgcaattttg gacagtcaaa gaatttcaga agtttttgac actatttgaa cccgaagaat
     6241 acaatatcaa actactcttt actgttctat tctttacagg attaagactt ggggaagctc
     6301 ttgccctaac atggcaagac atcgactttt caagtaatac aattcatatc acgaaatctg
     6361 tctatgttaa taaaggagta actcatatca gcacaacaaa aactaaagca ggaacaagaa
     6421 gaattgttat caataaaaaa ttaagccaag aattacaaga ttgggaaaag cgacaaaaac
     6481 atctattaga gcaatttacc aacaatagcc taacattaca agtgtttcaa aatagtccta
     6541 tcacaattac gaaaaatgct attgaaaagc agtacaagaa aatcattgaa cgtgatagca
     6601 cactaaaaaa gatacgcata cacgatttta ggcactcaca cgcttccctg ctgattaacc
     6661 aaggggaaga ttatctagtt gtaaaagagc gactaggaca tgcttctata acaaccacga
     6721 ttgataccta ctctcacttg tacccaagta agcaaaagga tttagctgat aaactagatg
     6781 atttactata aagtaattga gttttataaa tggaaagttt ataattaaat catggataca
     6841 tcacaagtaa taaaagcaca tgaagtagct aaaaaagcac actttggaca aattgataga
     6901 gcaggaattg actacattaa acaccctgaa atagtagcta gttttgtcgc aactgatgaa
     6961 gagaaagctg tcgcctatct acatgatgta attgaagata cttcactaac cctactagac
     7021 ctaaaaaagg aaggtttttc aaaaaacatt atagaagccg tcgatatact cacaaagaaa
     7081 aaaggacaag attatcaatc ctatctcaat ctagtaaaga aaaatgaact cgctagagtt
     7141 gtaaaattgg cggatttacg gcataattca gatttaacaa gactaccatt aattactgaa
     7201 aaagacttag agagaaataa gaaatacagt tctgctatta gatttttaag agcaaagaaa
     7261 aaaagttagt aactaaacta taaaatttta taaagagaaa ataaaagaca aggcttataa
     7321 actttgtctt tattactata ctggcggtcg gtctcgaact ggcacatcct tgcagatact
     7381 acaattttat taaaataaat aactataaaa agtgaaattt tttattgaga aacttttaga
     7441 ctaggagtat aatgtatcta aaataactat taggtggctg ttatatgaat aatgttgtta
     7501 ctacacaaat ttctattcaa cttagtcaag agttaaattc tttattaaat gctattgttg
     7561 aagaaaataa tacaacaaag actgacttta ttagacaagc tgttatagag aaaattgaag
     7621 atatgtatga tattaaggtc gctgatgaag cttataaaaa atggggtgaa tgtggcaaaa
     7681 aagctatctc acatgaagaa atgatgagac gctatggcta aattatacgc aatatctgat
     7741 atacatggat acttggatga attcagagac gctctcaata aagtaaattt aaacgataaa
     7801 gataatcgcc tatttttact aggagattat cttgataatg gacttcaatc ttttcaagtc
     7861 atttccaaaa taatcgaact tgaggaggtt tatcctaatc aaattattac tcttctaggg
     7921 aatcatgaag aatggtttta tgattggttg attttagata aacctactgc ttcagcattt
     7981 ccagaaacaa taaaaagctt cttctctcca gaggaattaa actatatttt taaatcgaat
     8041 gctaacaact ttgaaacagg tgttagaaat gaaattaaaa ataatatcaa attcaaccca
     8101 tttataaact ggtttaaaaa gcgatatagg gataaacgct attatgaaac tgatacccaa
     8161 atttttgttc atgcaggcat tgatgaagaa gcaggaatgc tttggaaaga actaacgagt
     8221 tcaaagatat ttacaaacaa atttccaatt accactggta gatttcataa agctattatt
     8281 tcgggccata ttgcttcttg ggaagtagct aaagatagaa gatacctagg taagatttac
     8341 tatgatagta aaagtcatta cttaattgat ggagatgtaa cgaatagcaa aacaatacct
     8401 gttctttgct atgatacaat tacccaaaaa tatcactttc tataactttt agtcatgtgc
     8461 ttttatatga aattagtaat tattagtaac aattccaaga aatttcttat gacataacaa
     8521 aaagacaagg cttataaacc ttgtcttcta aactataccg gcggccgggg tcgaaccggc
     8581 acgtccttgc ggacactgga ttttgagtcc agcgcgtctg ccaattccgc cacgccggca
     8641 aatagtaact ggggtagctg gattcgaacc aacgcatgag ggagtcaaag tcccttgcct
     8701 taccgcttgg ctatacccca atataaaata ggcgagtgat ggggatcgaa cccacgcatg
     8761 ccagagccac aatctggtgt gttaaccact tcaccacacc cgccataatt ctattaacac
     8821 gggcagtagg aattgaaccc acactgaagg ttttggagac cttagttcta cctttaaact
     8881 atgcccgtaa aatggaaggg gagggattcg aacccccgaa cccgaaggag cggatttaca
     8941 gtccgccgcg tttagcctct tcgctaccct tccaaaatat ataaatggcg cgagacggaa
     9001 tcgaaccgcc gacacatgga gcttcaatcc attgctctac caactgagct accgagcctt
     9061 attgcgggag caggatttga acctacgacc ttcgggttat gagcccgacg agctaccgag
     9121 ctgctccatc ccgcgttaat ataaaaggag gatgtgggat tcgaacccac gcacgctttt
     9181 acacgcctga cggttttcaa gaccgttccc ttcagccgga cttgggtaat cctccaaaat
     9241 agtttatacg ggaacaagcc cgtgtcctct tagtgaacag ataatattcc aatcccctag
     9301 taatggacta aacactatgg gcacgagtgg actcgaacca ccgacctcac gcttatcagg
     9361 cgtgcgctct aaccacctga gctacgcgcc caagtcaaaa acttggtaca aagaacaaag
     9421 ttcaaagcgg gtgacgagaa tcgaactcgc gacaacagct tggaaggctg tagttttacc
     9481 actaaactac acccgctaaa
//
LOCUS       DAVMBH010000066         9402 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVMBH010000066 DAVMBH010000000
VERSION     DAVMBH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.066"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            144..1322
                     /locus_tag="VYP30_001920"
     CDS             144..1322
                     /locus_tag="VYP30_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1808846.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDSNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1550..1996)
                     /locus_tag="VYP30_001921"
     CDS             complement(1550..1996)
                     /locus_tag="VYP30_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808847.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLKDSNLHIGRFFINPQKQGQGLGSQTLRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            2066..2725
                     /locus_tag="VYP30_001922"
     CDS             2066..2725
                     /locus_tag="VYP30_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1808848.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLKKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2697..3473)
                     /locus_tag="VYP30_001923"
     CDS             complement(2697..3473)
                     /locus_tag="VYP30_001923"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1808849.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(3466..4689)
                     /gene="trpB"
                     /locus_tag="VYP30_001924"
     CDS             complement(3466..4689)
                     /gene="trpB"
                     /locus_tag="VYP30_001924"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1808850.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(4667..5266)
                     /locus_tag="VYP30_001925"
     CDS             complement(4667..5266)
                     /locus_tag="VYP30_001925"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1808851.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            complement(5253..6020)
                     /gene="trpC"
                     /locus_tag="VYP30_001926"
     CDS             complement(5253..6020)
                     /gene="trpC"
                     /locus_tag="VYP30_001926"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1808852.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(6017..7021)
                     /gene="trpD"
                     /locus_tag="VYP30_001927"
     CDS             complement(6017..7021)
                     /gene="trpD"
                     /locus_tag="VYP30_001927"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1808853.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(7032..7598)
                     /locus_tag="VYP30_001928"
     CDS             complement(7032..7598)
                     /locus_tag="VYP30_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1808854.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEEGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(7595..8956)
                     /gene="trpE"
                     /locus_tag="VYP30_001929"
     CDS             complement(7595..8956)
                     /gene="trpE"
                     /locus_tag="VYP30_001929"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1808855.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
BASE COUNT         2582 a         2224 c         1785 g         2811 t
ORIGIN      
        1 aacatttgat tattttttat tatcaatata taataaaaag agaccagtaa gtaatgaaaa
       61 gcttaaaaag attaacatct acatttatcc atagcaaaaa atcataggat tttaagaatc
      121 tgacaactag gaagaaaact aatatgacct tatctaagaa acaattacaa ctaagagcta
      181 aaatactgga aacagtttac acattaggtc ccatttcacg aattgaaatc gctactaaaa
      241 caggaataac acctgcaaca actagcagta tcacaaatga tctgattaaa gaaaatattc
      301 tcttagaact tggtgaagac gaacacgata caagcgtagg gagaaaaaaa atcctgctag
      361 acattcaagc taaacgattt tactacattg gttgtgaact atctgaaaaa catttcactt
      421 ttgctttagg agataatcta ggaaatatct taaaggaaga gaaagaaatt gttactaaac
      481 agttaatcca agaaaaggga aatcaactca ttaaccagac actaaagcaa ttcttaaata
      541 actgctctga ttatgaaata gaagcaattg gaatcgcgct acctggtcgc tatttagatg
      601 attataaaat aacaacaaac aatcctttat ggcaacatat cgacttagaa atgattcaat
      661 cccactttga taagcctttg tttttctcta acaatgttaa ctgtatggct ataggtaaac
      721 gcctatttag tcgccaacag aatgactcta attttgctta ttttcatttt gctagaggta
      781 tgcactgttc ttatatctac gacggaaaca tttatgggaa aggaaatcta atgattggag
      841 aaatagggca tacagttgtt tcatctgagg gagaagaatg tagctgcggg cgcaagggat
      901 gcttacaaac ttttgctgga gaatcttggt taatcaaaaa atcaaaaatt ctatatcatc
      961 aatctcccta ttctctactt cctagtttag tcaaaaatgc cgatgatatt gatatccaag
     1021 ttattttaac cgcttatcaa ttaggtgaca ctggaataat cacacttatc catcaagcct
     1081 tactctatct tagtcaaacc attttaaata tcagtatgat gattgactct caaaaaatct
     1141 acctacatag tcctttacta acaaatcaac acatcatcca aaaactatat agtgaaatga
     1201 actacaaacc caaactgctc tataatcgcc tacctgaagt cattattgaa ccttacaatg
     1261 attttacagc cgcacactca gctattgcac tttgtttgta tcatacaatt ctacattctt
     1321 aattttctat tacatttaat aaataggcta aaaagaggga gtatatcata aaaagcgaat
     1381 aaacctgttt tctgaaaatc agaattctgt tttgttcgct ttctttatat ttggaattat
     1441 actcctatct cccatttttc ataatgtata gtaaaatgaa ataataacag gacgaatcga
     1501 tcgggacagt caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
     1561 tcaatccact atattttcgt acaggtgctt caaccatttg aacgatttca aatccttctt
     1621 tttggtaaag attctgagct ctttgatttg cctcgaagac atttagagaa atattatcta
     1681 tatcttcatt ttcaaaggcc aaactaacaa atttccttaa agtctggcta cctaagcctt
     1741 gcccctgttt ctgggggttg ataaaaaatc tcccgatatg aagattgctg tcttttagcc
     1801 tgattttctg gataaggccc acaaactctt gttcatcaaa gattgaaaat acttcttcca
     1861 aggcttgaag ggtcagtaga aaaggaatcc ttggtcccat ccattgttct tgaaaggatt
     1921 tgcctaggga gttggaccat tggcatacaa attgagcgtt ttctatactc accttttctt
     1981 caaaacgaat tgtcatcttt tcctcaccat cttatctatg tttctccatt atactatttc
     2041 tcccattttt tacgaataga taagtatgat tgatttttat ttttttctcg tcgggagcat
     2101 tctcgcttcc tttcttggtt tggtcattga ccgttttcca gagcaatcca ttatcagttc
     2161 agccagtcac tgcgattcct gtcagactcg cttgcgtccc ttagatttga ttccgattct
     2221 ctcacaggtc ttcaatcgct ttcgctgtcg ctactgcaaa gttcgctatc ctgtctggta
     2281 tgccctcttt gaactaggct taggactcct ctttctgctt tactcttggg aattgctttc
     2341 cttggggcaa gtcgtcctaa tcaccgctgg tttgaccttg ggtatctacg actttcacca
     2401 tcaggaatat cccttactgg tctggatgac tttccaccta atcctaatag cttcctctgg
     2461 ctggaatctg gtcatggtct ccttccttgc tcttggaatt ttggctcatt ttatcgatat
     2521 ccgcatgggc gcaggagatt tcctcttttt agcttcttgt gctctcgtct ttagcgtaac
     2581 ggagttactg atcttgattc agtttgcttc tgcgacgggt atcctggcct ttctcctgaa
     2641 aaagaaaaag gaaagacttc ctttcgtgcc tttcctctta cttgctactt gtttgattat
     2701 ttttggtaag ctactgcttg tctgataaaa tcctgaatcg gctctccttg gtggagagct
     2761 tttactattt ttgaaccgac gataacacca tctgacaccg cattgaagcg ttccagatcg
     2821 gcttgactag atacaccaaa acctgtcaag actgggatgt cggccacttg atgaagttgc
     2881 gccaagtgct tgtccaaatc tgcacggtaa ttgcctgatt tccctgtcac tccattgatg
     2941 gcaacggcat agacgaatcc ctccgcccct tcaatcaact ctttctggcg ctcaattcct
     3001 gtggtcaagc ttactaaagg aatcaaggtg atatctgtat ctgccaaaaa tggttctaca
     3061 aagttggcat gttcatgagg caagtctggg ataatcaagc ccttcacagc tgtatcagcc
     3121 agatctttga caaagttctc cacaccgtac tgaaagaggg ggttgaagta ggtcatgatg
     3181 accagtggaa tctctgtttc aatggttttc aaggtttcaa ctaaagcctg ggtagaggtc
     3241 ccgtgggcta aactgcgcaa gccagcttct tcgataacag gtccatctgc aacagggtct
     3301 gaaaagggaa tacccacttc aattgcagag acacccaaat cttctaaaaa gtgaattgtt
     3361 tcagcaagac cgtccaaacc tttctcgtgg tcaccagcca tgatataggg aacaaaaatt
     3421 ccttttccag ctgctttaat agcattcaat ttttctgtta gtgtcttagg catgagcttc
     3481 tcccttcttt gctgcatctg cttccaagcg gtctttgact tgaaccacat ccttgtcccc
     3541 acgacctgat aggcagacaa tcatagactt ttctggtcca agttctttgg ccaatttcac
     3601 cgcaaaggcg atagcatggc tagattccaa ggctgggata atcccttcca cacgagacaa
     3661 gagttggaat ccttccaagg cttcttcgtc tgtcacaggg acatagctgg cacgtttaat
     3721 atcgtggtag tgagaatgct ctggaccgat accaggatag tccaaacctg ctgagataga
     3781 gaaggcttca agaatttgac catgggcatc ttggagcaca tccatgaggg aaccgtgaag
     3841 gacacctgga cgacccttgg tcaaggtagc tgcgtggtgc tccgtatcca caccaagtcc
     3901 agccgcttca gctccataca tggctactga ctcatcttct acaaagggat ggaagagacc
     3961 gatggcattc gacccaccac caacacaggc tactagggca tctggcagat tttgtcctgt
     4021 caagtcacgg tactgttgtt tagcctctcg accaatgaca ctttggaagt cacgaacaat
     4081 ttctggaaat ggatgaggcc ccaaggcaga accaaggata tagtgggtat catctatatt
     4141 agccacccat gaacgaagag ctgcattgac cgcatccttg agcacgcgcg aaccatctgt
     4201 cacggcctcg accttagctc ccaaaagctc catacggaag acattgaggg cttggcgttt
     4261 gacatcttcc tcacccatgt agatggtaca ttccatgtta aagagggccg cagcagttgc
     4321 agttgccaca ccgtgctgac cagcaccagt ttctgcgata attttctttt tacccatgcg
     4381 tttggcaagc caaacttgtc ctaaggcatt gttaatcttg tgggctcctg tatggttaag
     4441 gtcttcccgt ttgagataaa tcttggctcc gccgatatgc tgggtcaagt tttttgcgta
     4501 gtaaagggga gtttcacgtc ccacatactg gcgcaaaagt tggtttaatt cctcttggaa
     4561 acttgggtct gcctgacttt cacggtaggc cttctccaac tccaaaactg ctgtcatcaa
     4621 tgtttctggg acaaaacgtc cgccgaattt tccgtaaaat ccatctttat ttggttcttg
     4681 atatgccatt ctttaccctc tctataaatc ttctaatctt ttcatgatct ttttgtccat
     4741 ctgtctccac tccgcttgat acatctactg catagggagt aaagtgttga attgctttta
     4801 ctacattgtc ttcattaagc ccacctgcga taaagaaaga ctgaggtaat ccagtcgtat
     4861 ccagttgacc ccaatcaaag ggctggccac tcccagccac aggggcatca aagagtagat
     4921 agtctgcctg agaattgggc acatgaccct ctccatctac ctgcacagcc tgaatgctag
     4981 cacaaggcaa attctcaaat aaatcatctg ccacctgacc gtgaacttga accaagtcca
     5041 agccaacttt gtcaatcgct tccagcagtt ctacccgact tggtgaaaca aatactccaa
     5101 cctttttcac atctgcagga ataagctttg ccaactcagc tgcctcttct aaagtcacct
     5161 gtcttttact aggtgcaaag acaaaaccga tatagtcggc tcctgctgaa acggctgttt
     5221 ccaccgcttc tttggtcgat agtccacaaa ttttaacctt tgtcaatctg caactccttg
     5281 attctctggg ccacattttc tgcctgcata agagctgtcc ctaccaaaat tccgttaaag
     5341 tatggggcta gtcgttccgc atcctgccct gtgaaaatgg cagattcaga aatgtaatag
     5401 cgaccttcct caaagtaagg ggctaaatct acactggtct gcaagtcgac ctcaaaggta
     5461 gtcaagttgc ggttgttgac cccgataatc tcagcaccaa gtctgtgggc tacctctagt
     5521 tcagctagat tgtgagtctc cactaagact tccagaccaa gctctgtcgc gtagtcatac
     5581 agttccttga ggcgttcttc ggacaaggct gccacaatga gcaagataac tgtcgcacct
     5641 gcattgcgag cgcggatgat ttgcttttca tctatgataa agtctttgtt gagcgtcgga
     5701 atctctacct gactggaaat ttcccgtaga taatccaaat gccctttaaa gaaaacctca
     5761 tctgtcaaca ccgaaatcat cactgctccg ttttcttcat aagtctgggc ctgttgcaca
     5821 atatccacat cgagattgat atctcccaaa ctagggctag ctttcttgac ctcagcgatt
     5881 acctgcaagc ggtcctgatg attcttcaaa aattctgcca agcgataggt ctggcgcaga
     5941 ggctggattt gctccagctt catctgctcc acctcacgcg ccttctgctc taagattcgt
     6001 gctaaaaatt cctgactcat ttttggtact cctgtaacag tctgagtttt tcaagggcct
     6061 tgcctctagc aatcacttga cgagccaagg caactccttc cttgatgcta tcaatcttac
     6121 cattagcata gaaaccaaga ccagcattca agactgtcgt ttccaagaat ggacttgctt
     6181 cgtttttcag aacgctaagc aaaatttctg cattttcctg agcattccca ccacgaatat
     6241 cttccatagc atagccttcc attcccaaat cctctggagt aaagcttgac aagctgattt
     6301 cgccattttc aagaagtgca atcttggttg ttccgttcaa gccagcttca tccaaccctt
     6361 ctggtccagc aaccacgatg gcacgtttgc gacccatatt tttcaaaacc tgagctgtac
     6421 tttctaggag ttctggacga ctaattccaa gaagctgtgt ttctaaagcc attggatgaa
     6481 tcagtggacc agtcaagttc ataatcgttg gaattcccaa ttccaaacga gctggcatga
     6541 tgtatttcat agctgggtgc atatttttag cgaagagaaa gacgattcca gttttatcaa
     6601 agaccttacc tagttcagct ggtttgaggt caagattgat tcccaaggct tcgaggacat
     6661 ctgcggaacc agatttagaa gaaatcgagc ggttaccatg cttggccatg tgaataccgc
     6721 caccagccaa gacaaaggct gcagttgtgg aaatattaaa actgaaagac ttgtccccac
     6781 ctgtaccaca gttgtccatg gcatcatgaa tctcagttgg aatatgctgg gcatgtcctc
     6841 tcatgacttg ggcaatggct gtgcgttctt caggtgtttc ccccttcatc ttaagagcta
     6901 agaggagaga agcaatctgc gcttcagtta cacgcccagt tacgatacgc tcaatgacat
     6961 ccgtcatttc cacacctgat aaattttcaa attttgctag tttttcaata atctctttca
     7021 tcctagtttc ctcactttac aaccttctcg ataaaattcc gaatagaaga caagccgtct
     7081 ggcgttccaa tgctctctgg atggtactgg aagccataaa tcggtaggtt tttatgttga
     7141 atccccatga tggcttggtc atcagtcgaa cgagctgtca cttcaaagtc ttctggcatt
     7201 tcctcaatca aaatactgtg ataacgcatg accgcacgtc cttcctcaat accttgatac
     7261 aaaacagatg gcgcttcaaa gttgatattg ctctgtttcc catgcatgac ttttggagcc
     7321 aaacctagct taccaccaaa gacttctgca atggcttggt ggcccaaaca aatcccaaga
     7381 atcggcttct tgcctgcaaa atcacgaatc atgtcttcca tctttccagc atcaactggc
     7441 caaccaggac caggagaaaa gaccagacca tctgcttttt cagcttcttc atacagcttg
     7501 gaatcatcat ttctcagaac ctgaacttct gcaaaattcc caatgtattg ggccaagtta
     7561 taggtaaaag aatcatagtt gtcaatcaat aaaatcatgg tcttagttct ccaattctag
     7621 tcatagattt tgctttgtta atggtttctt ggtattcgtt ttgggcgata gagtcgtaga
     7681 caatccctgc cccagcctgc acataggctc tttgattttt gagaatcatg gttcggatgg
     7741 caatggccaa atccatatca cccgtcgcag acaagtagcc gattgctcct gcatatacgc
     7801 cccgtttttc cgtttccagt tcatagatgc gtctcatcgc ccgaatcttt ggtgctccag
     7861 aaacggttcc agcaggaagt gtagctttca aggcatccat ggccgtgagt tctggaagca
     7921 aacgcccctt gaccacgctg gtcaaatgca tgacgtagcg gaagagctcc accttcatat
     7981 acttagtaac ttggacactg gccgtttcag agatgcggcc aatatcgtta cgccccaagt
     8041 ctaccaacat tcgatgttct gctgtttcct tctcatcaga gaggaggtca gtcgccaagg
     8101 tcttgtcttc ttcatccgta gcccctcttg gtcgcgtccc tgcaatcgga ttggttgtca
     8161 cgatgccatt tttgacagaa actaaacttt ctggactagc tccgatgatt tgataatccc
     8221 caaaatcata gaaataaagg taattagaag gattagtcac gcggagattt ctgtagaagt
     8281 caaatggatt tccagtaact tctgctgaaa aacgctggct gagtacacat tggaacatat
     8341 ctccgttacg aatcaagtca cgagctgttt ctaccattcc ctcaaactta tgtggagcga
     8401 tatgcggttt gaagtctaac ggagatagat ccaaatcttc aaattcattt ggagcaggaa
     8461 tgcgtaattc ctcaagcact tggttcaagg atttttccaa ggcctcttga ctgcgctcac
     8521 tataaagtgc atcctctatg acatgtatct tctccttctt gtggtcaaag accatatagc
     8581 tctcatagac aaagaaatgc atgtctggcg tcccaattgt atcctcaggg atttgaccaa
     8641 tttcttcata aagcgaaatc atatcgtaac ccacaaaacc aatggctcca ccaccaaaag
     8701 gtagctctga gtggtgctga ctcttatgaa tcacttcata aaggaaatcc aagggatccc
     8761 gatcaatcac ttgaccattt tgatagagaa ccccattttc aaacttaatc tcaaaaactg
     8821 gattataggc taggatagaa aaacgagctg tttccttgtc tctcggaata ctctctaaaa
     8881 taaccttatg ttgccccttt aagcgcatat aagccaagat tggtgataag acatctccat
     8941 gaatgattcg ttccattgta atttcccttt cagttctact tctagtccgt ggtgactgta
     9001 tgaaaaatcc ccacgcaaaa taacttgcgt gaggacgaaa ttcgcggtgc cacctcaatt
     9061 ataggatttc tcctatctct cattcctgtc tcagatatct cctgtaacag gctgtgcgat
     9121 aaagggcact cccttgagaa tgatgttttc ttctctcgtt tcagatgaac ccaactttac
     9181 agctttctct gcttgttttc agcaaccaca agctctctgt gagagaaaga actgtaattt
     9241 ttccatctat tattttttag cttctagtaa tctgcaatcg cagctaggtc cttgcctcca
     9301 cgaccagaga cattgatgaa gagatgttca tctcggtaca cctttatact cttcgaaaat
     9361 ctcttcaaac cgcgtcaacg tcgccttgcc gtaggtatgg tt
//
LOCUS       DAVMBH010000067         8517 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVMBH010000067 DAVMBH010000000
VERSION     DAVMBH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8517
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.067"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(33..197)
                     /locus_tag="VYP30_001930"
     CDS             complement(33..197)
                     /locus_tag="VYP30_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1808856.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(364..1959)
                     /locus_tag="VYP30_001931"
     CDS             complement(364..1959)
                     /locus_tag="VYP30_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808857.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(1971..2381)
                     /locus_tag="VYP30_001932"
     CDS             complement(1971..2381)
                     /locus_tag="VYP30_001932"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1808858.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETTRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(2497..3288)
                     /gene="yghU"
                     /locus_tag="VYP30_001933"
     CDS             complement(2497..3288)
                     /gene="yghU"
                     /locus_tag="VYP30_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1808859.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(3301..5997)
                     /locus_tag="VYP30_001934"
     CDS             complement(3301..5997)
                     /locus_tag="VYP30_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1808860.1"
                     /translation="MSKEQKRQAFYTQSPEEVLKAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            complement(6235..7206)
                     /locus_tag="VYP30_001935"
     CDS             complement(6235..7206)
                     /locus_tag="VYP30_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1808861.1"
                     /translation="MNRNNPILYIVIPCYNEEQVLPYTNPMFVEKIEQLVKKEEIHPL
                     SKIMYVNDGSKDRTWELIESYANSIPSVVGVSQSRNRGHQSSVLAGMYEAIQFADIVI
                     TTDADGQDDINCMDKMISEYKSGSEIVYGVRDNRDTDSAFKRITAEGFYKVLRLFGAE
                     VVFNHADYRLVSKRFLKELEKFTEVNLFLRGLMPLVGFKYSYVSYKRHERIAGESHYP
                     LSKMLGLAMDGITSLSIKPIRLITSLGVLTSLFSFLLIIWVLLSKFVGTVVTGWASTY
                     AIVSLLGEVQLISLGVIGEYIGKIYLETKRRPRYIISERTFDKDRIL"
     gene            complement(7193..8497)
                     /locus_tag="VYP30_001936"
     CDS             complement(7193..8497)
                     /locus_tag="VYP30_001936"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808862.1"
                     /translation="MALSAFLFFIQLFLIFHYYFYTDWDVQELLKNAIALSDKNFSEL
                     NNFYFSRYPNNILLTVFFSKIFTLFNGLLGQDFAYVFLLVIQSILNIFSGFLILKVTF
                     LLTKSEKYAFFSYWLYLLILWISPWVVIPYSDSMGLIFPILMYYIYTHPKMHYILKSV
                     LLSAIGIIGYSVKPQIAIMIIAIIMVSLLTQKIEMKPLIAAIIAIFVVSFPMFFAINR
                     INSTAGFDLDYEWEMTYHHFIKMGLNSETDGGYLANDVNGSISIENKEERVIYNKQII
                     AQRIKDYGVTGLINHQAKKTLNNYNDGTFGWGLEGSFFEKIFPNDSYVAKITRSFYYS
                     SGKLHLIFQGIVQSVWLSILFLVLGNVLIGREKMTREFLVLMTSLIGIFLFESIFESR
                     SRYLYTFIPIYIVAATVGFQQMTQNFKKRALKLKTGVKNEQK"
BASE COUNT         2623 a         1847 c         1546 g         2501 t
ORIGIN      
        1 gaaaaacctc ggtttgaccg aggtttttct atttatttgg gccatcctaa ccagacagcc
       61 acgagaacaa gggctgtgcc agctaaactt gttaagatag ataagaattt atcttttttc
      121 tccttgaact gagaaaaacc tatcttcaaa gcgagcagtc cgagtagcat tgaagcaacc
      181 atcaaataaa aacccatttc tttgtcctcc attaggctta atttacctta ttataacata
      241 tatttattaa ataaaccttt tttatactca atgaaaatca aagagcaaac taggaaacta
      301 gccgcaggct gctcaaaaca ctgttttgag gttgcagata gagctagaga ttttcgaaga
      361 gtattattgt actttaaagg tcttgagata attgtctttt cctacttgac cttcgaaggt
      421 tttaccattt tcaaggtaag gaaggtcatc ggatactgaa gcctttacct tgtatatctt
      481 gccatcaact ttaaagaagt agacagtgtc tcccttgata acagctgatt tgaggtctgc
      541 tactactccc ttgatgcttt ctgtcgttgc attgtcaatt tcaaggtcgt ttttattggc
      601 atacttgctg agcatctctt ccactgtagt agcaacgata acattttggt actcgactgc
      661 gtctaccagg gcgtactctt tgaccaagcc agcattgtcc tttaagccca tgatgtagag
      721 aggcttgtca ttgaggttga tgaggattgg gaaggttgct ttgtaggatt tctcctgaac
      781 agcaccttct gctgattcac gggctgattc ttctgtcgca gaagccaagc tatacttagt
      841 aatttctcct gttcgcatat tttcaaggat gaaaccaaga ttactctcat ccgcattagc
      901 cgacgtcaca cctgtgtaga gatagatgtc attaccgata gacaagtaat tatagccatt
      961 ggtagtctgg gtcacgtttt tcttggaaat catggcattc aagaaaccgt ccttgtactt
     1021 gccgttgtag ttgatttgct caatggtttc ctctgctgga tagatcctgt ccacccattc
     1081 tggaacatct gataagctgt attccttggt ttctccattt gtagcatcca agataatgac
     1141 tgaagcagga cgaggaaccg caagtccaaa ttgcttttgg taaaccgttg ctacatagaa
     1201 aggattgccc tcatcgtcca cctcaaaaga tggagtttta aagattttag tcgggtactt
     1261 caagcgcagg tgacgtttga catcacggtt aaaatactcc gagtctgaat acttgattgg
     1321 tgtcttcaag tccaccaaat ccgcatttcc agttaccatg tccaccttga tatactcacc
     1381 gattcccttg gcttgattgt taaaccattt gatagggtct gcatattcta gtggtgtgac
     1441 ccgataaggt ttcccatcaa ttgtcaattg ggtataggta tctgccgcta cgtattgcga
     1501 caccttatcg gttagggaac ccaagtagcg gtctccaatt ttttcagcag tacttctatc
     1561 taggatagga accttactgg tgtcactcct aggaaattca gtaaagtctt tttccgtaac
     1621 cgtgactaca ttggcataat ttttagcctg aaacatgctg gaagttacca aggaaaccaa
     1681 agctgccaag agaagaattc ctccaatcga agctaacaga attttcccta accgattgat
     1741 tttgaaaccc tcaagattta aggcagcttc cgccttaccg tggcgcacat gaaccgtttt
     1801 gacaaggttt atccccttgc caaagccaaa taagattgcc acaactaaca aatgcccaca
     1861 gaggaagaag agaaattccc agctggtcag gttaaggggc ggtaaaaaga tataccaggt
     1921 cgttgcgata aaaataagtt caaagactat tcgtttcatt tgctttcctc ctaaatgatt
     1981 cgtccttcca agtgatccag ctcatgctgg caaatctgag ctgggaagcc tgtcaaggta
     2041 atggtctgtt cctgccactt gctgtcacga taggcaagcc ttgtggtttc ataacgctta
     2101 gttgatctca cacctaccaa ggacaaacag ccttcttctg cctcatagga tccttcaaag
     2161 gacagaagca ctgggttaaa catgaccacg ggaaccaagc caagattaaa gataatcacg
     2221 cgcttctgca ccccaatcat attggcagct agaccaacac aggtatcacg atttgctaag
     2281 agtgtatcct gcaaatctct ggcaagataa aggtcctcct gacttgccgg ctgagacact
     2341 tgagataaaa ataagatatc cttcacaatt ttcttttcca cttcctcaca ctcctcttgc
     2401 tttttactat attatagcaa ttatagcaca aaagccgata actgcaaacc ctttccctca
     2461 actgtagcaa aaagccatcc gaagatgact tttttgctat ttaatttctg tataagttac
     2521 ttccaagcca cgcttaacag ctggacgatt ggcaattttt tctgcccatt ttactagatt
     2581 ttgataactt gaggcatcca agaattttgc agaaccttgg taaagatttc cttgaactaa
     2641 ctgtccatac caagaccaga tagcaatatc tgcaatcgta tagtcattgc ctgcaatata
     2701 aggtttctga gccaattcct tatccaataa atccaactgg cgtttcactt ccattgtaaa
     2761 acggttaata ggatattcca atttttcagg agcataattg aagaaatgtc caaatccccc
     2821 acctagaaaa ggtgctgcac ctgcttgcca gaatagccaa ttcaaaactt ctaccttttc
     2881 cacaggatta cttggtaaaa aggctccaaa tttctcagca aggtaaagaa gaatatgagc
     2941 agactcaaag actcttacat cttcagtacc tgactggtcc aataaggctg gaatcttgga
     3001 atttggattg agcttcacaa agtctgatcc gaattgatcc ccatccatga tagcaatctt
     3061 atacaagtcg taagccgctt ccttaaaacc agcttctagt aattcttcca ataagatagt
     3121 aaccttcaca ccatttggtg ttcccagtga ataaagctga aaagcttgtt ctccttttgg
     3181 caagttttgt tcgaaacggg cacctgctgt tggtctgttt agccccgtaa aagctccttg
     3241 attactagct tcatcctgcc atacggtcgg taattgatat gctgacatcc gaaacctccc
     3301 ttaaatcgca ttcttgtcaa aaccgagttt gcgttgaata aacttaacga tttcgacgat
     3361 gataatcatt gagaagcttc cagccataac aattccccat tgtgacaagt ctagtttggt
     3421 tacgtggaag attccttcaa gcggttctac aacgattgtt gccatgagaa ggataaagga
     3481 taccaagatg gaccagttaa aggtcttaga cttgaatggg ccaactgtca agatggattg
     3541 gtagacagac ttgacattgt aggcatggaa gagctgaatc aaaccaaggg ttgcaaaggc
     3601 catcgttagg gcatctgcat gaatagcatg attgtcaccc acatgaactg ggtaagcaat
     3661 cgcaaggcca taaacactca taacaagagc tgcttggagt acaccttgat aaatgataga
     3721 actcaaaaca ccacctgaga agaagcttgc cttgcgtcca cgtggtttat gattcatgac
     3781 accaggctcc gcaggttcaa caccaagagc gatagctggg aaggtatccg ttaccaagtt
     3841 gatccacaaa agatgaaccg gctgcaagac atcccaacca aacaaggttg ataggaagat
     3901 ggttaatact tcagcagtat tagcagaaag taggtactga atagtctttt gaatgtttga
     3961 gaagacctta cgtccttctt ccactgcgac gataatagtc gcaaagttat catctgcaag
     4021 aatcatatca gaagccccct tagaaacctc tgtaccagtg attcccatac cgataccgat
     4081 atcggctgtt ttcagagctg gcgcgtcatt gacaccgtca cctgtcatgg caacgacttt
     4141 accttgtttt tgccaagcct tgacgatacg aaccttgtgt tctggagaca cacgggcata
     4201 aacagagtat tgaccaacga ctttttcaaa ttcttcatct gacagttcat tgagttcagc
     4261 accagttaaa acgtgacctt ctgtatcgtt tgcgtcaatg attcccaaac gtttggcaat
     4321 ggcttccgct gtgtcttggt ggtcacctgt aatcataatc ggacggattc ccgcttcctt
     4381 agccacacga acagcctcag cggcttcagg acgttcaggg tcaatcatcc caatcaaacc
     4441 agtaaaaatt aaatcatttt caagctcttc agaagtgaga ttttctggaa tactatcgat
     4501 aatcttataa gcacctgcaa ggacacgcaa ggcttgatga gccatttcag aattgtttgt
     4561 atgaatgaga tttgtaacct tctcatcaat cggagcaata tccccagcct tatcacgaag
     4621 aagacaacgt tttaagagtt ggtctggcgc acccttgact gctacaagga aacgaccatc
     4681 tggcaatggg tgaactgttg acatgagctt acggtcagag tcaaatggca attcagctac
     4741 acgaggatat ttctctaaga aacctttgac atcatagccc ttgtccaagg catattggat
     4801 aaaggctgtt tcggttgggt caccaatcaa gttaccttcc acatcgattt tcgtatcatt
     4861 ggccaagaca actgaacgaa gtagtggcat ttcaagacct agttcaatat catcagctga
     4921 gtcatgtaga accgcatcgt agaagacttt ttcgactgtc atcttgttca tagtcagcgt
     4981 accagtctta tcagaagcga tgatttcagt tgaaccaagt gtttcaactg ctggcaactt
     5041 acgaacgatg gaatgtcgtt tggccaaaac ttgagtacca agagaaagaa cgatggtaac
     5101 gatagcagga agtccttctg gaatggctgc aacggcaagg gcaacagaag tcaacaactc
     5161 accaagtgga tttttccctt gaatgaagac acccactaca aaagtaacaa gggcaatgac
     5221 caagatagca taggtcaaga ccttagaaag gttgttcaaa ttttgtttga gtggtgtatc
     5281 agtctcatcc gcatcttgaa gcataccagc aatatgacca acttcagtgt acatacctgt
     5341 attgacaaca acacccatcc cacgaccata ggttacgttt gagttttgga aggccatgtt
     5401 gacacggtca ccaataccag catctgtcgc aagctcgact gacaagtctt tttcgactgg
     5461 tacagattca cctgtcaagg ctgcttcttc aattttaaga gagttggctt ctatcaaacg
     5521 taggtccgct ggtaccacgt cacctgcttc aagggcaacg atatcgcctg gtaccaattc
     5581 tttagagtca atctctgcca tgtgtccatc acgaagaacg cgggcaactg gactagacat
     5641 ggatttgagg gcttcaatag cttcttcagc ttttccttct tggtaaacac caaaggcagc
     5701 gttgatgata accacagcta ggatgataat ggcatctgcg atatcttccc caccagaagt
     5761 cacgactgac aagattgctg ccgcaactag gatgataatc atcaaatcct taaattgctc
     5821 gataaacttg accaggattg atcgtttctc gccttcttcg agttcattgt ggccaaattc
     5881 ggcaaggcgc ttttccgcct cacttgatga caaaccttgc tcggttgcat ccacagcctt
     5941 caagacctct tcaggacttt gagtgtaaaa cgcttggcgt ttttgttctt ttgacatgtg
     6001 tctcctcctt gacattgtgt gcaaaacaga ctctcttttt cccatcgtat cttttcacga
     6061 caaacaaaaa gagacctgtt aatcataaca agtctcgctg tttaagatag tgccggaaag
     6121 catacttttc agtataaaat tcggaatgac gacactatca caggtttctg ccagctactc
     6181 ccttgagtag tactattata ccaaattttg aaaagttttc aaagagtaaa gattctataa
     6241 aattctatcc ttatcaaaag tacgttcact gataatatat ctaggacgac gtttcgtttc
     6301 taggtaaatc tttccaatat actcaccaat tactcccaaa ctaatcaatt gtacttcacc
     6361 aagtaaacta actattgcat aggtgcttgc ccatccagtc acaaccgtac caacaaactt
     6421 actcaataaa acccaaataa tcaatagaaa actaaagagt gacgtcaaaa cacccaggct
     6481 tgtaatcaaa cgaatcggtt tgattgataa actggtaata ccatccatag ctaaaccaag
     6541 cattttagat agtggataat ggctctcacc agcaattcgt tcatggcgct tatatgaaac
     6601 gtaagaatat ttaaaaccaa ctaaaggcat taaaccacga agaaatagat taacttcagt
     6661 gaatttttct aattccttca agaatctttt agaaaccaag cgataatcag catgattaaa
     6721 aacaacttct gctccaaata agcgtagcac tttataaaaa ccttcggctg taattcgttt
     6781 aaaagcagag tccgtatcac ggttatcacg tacaccgtat acaatttcag aaccactttt
     6841 atactcagaa atcatcttat ccatgcagtt aatatcatcc tgtccatcgg catcagtggt
     6901 aatgacaata tcagcaaact gaatagcttc atacatccct gcaaggacac tactttgatg
     6961 ccccctatta cgactttgtg atacaccaac cacagaagga atggaattag cataactttc
     7021 tatcaattcc caagtccgat ccttactgcc atcatttaca tacatgattt tactaagggg
     7081 atgtatttct tctttcttta ctaattgttc aattttttca acaaacattg gattagtata
     7141 tggtaggact tgctcttcgt tataacatgg aataactata tataaaattg gattatttct
     7201 gttcattttt cactcctgtt tttaatttaa gagctctttt tttaaaattc tgggtcattt
     7261 gttgaaatcc cactgtagct gcaacaatat atatcggaat aaaagtatat aaatatcttg
     7321 atctggattc aaatatagat tcaaacagaa aaattcctat taacgaagtc attaatacta
     7381 gaaattctct tgtcattttt tctctgccta tcagtacatt ccctaaaact aaaaataaaa
     7441 tactcaacca tacactttgt acgattcctt gaaaaattag atgtagttta cctgaagaat
     7501 aataaaaact tctagttatc tttgctacat aagaatcatt tggaaagatc ttctcaaaaa
     7561 aactaccttc taacccccaa ccaaaagttc catcattata gttattaaga gtctttttag
     7621 cttggtggtt aatcaaacct gtaactccgt agtccttaat tctttgtgca attatctgtt
     7681 tattatagat aactcgctct tctttatttt caatcgatat tgaaccatta acgtcatttg
     7741 ccaaatatcc accatctgtc tccgaattta aacccatctt tataaaatgg tggtacgtca
     7801 tttcccactc ataatcaagg tcgaatcctg cagttgaatt tatgcgattt atggcaaaga
     7861 acataggaaa actcacaaca aatattgcga ttatcgcagc gataagaggc ttcatttcta
     7921 ttttttgagt caagagactg accataataa ttgcaataat cattatagca atttgaggtt
     7981 tcactgaata acctataatt ccaatagcac tcagtaaaac tgattttaga atgtaatgca
     8041 ttttaggatg agtatatata taatacatta gaataggaaa aataagtccc attgaatcag
     8101 aatatggaat tacaacccaa ggtgatatcc agagaattaa gagatagagc cagtatgaga
     8161 aaaaagcata tttttcactt ttcgtcaata agaacgtcac ctttaatatc aaaaatcctg
     8221 aaaatatatt taatatcgac tgaatcacga gtaaaaatac gtatgcaaaa tcttgtccta
     8281 agagaccatt aaacaaagta aatatttttg aaaaaaacac cgttagtaag atattattgg
     8341 ggtatcgaga aaaataaaaa ttatttaatt ctgaaaaatt cttatcagag agggcaatag
     8401 cgttctttaa tagctcctga acatcccaat cggtataaaa gtaataatga aaaatcaaaa
     8461 ataattgaat aaaaaataaa aatgcagaaa gcgccaaaac ggtctttcta ttgtact
//
LOCUS       DAVMBH010000068         8424 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVMBH010000068 DAVMBH010000000
VERSION     DAVMBH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.068"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..155
                     /locus_tag="VYP30_001937"
     CDS             <1..155
                     /locus_tag="VYP30_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1808863.1"
                     /translation="YLTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGTPDWNYM
                     ERYRDR"
     gene            121..435
                     /locus_tag="VYP30_001938"
     CDS             121..435
                     /locus_tag="VYP30_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808864.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1119..1280
                     /locus_tag="VYP30_001939"
     CDS             1119..1280
                     /locus_tag="VYP30_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808865.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1372..3051
                     /locus_tag="VYP30_001940"
     CDS             1372..3051
                     /locus_tag="VYP30_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1808866.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLGAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSFKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYERVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHECTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLCR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVEHRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            3319..3885
                     /locus_tag="VYP30_001941"
     CDS             3319..3885
                     /locus_tag="VYP30_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808867.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4207..4395
                     /locus_tag="VYP30_001942"
     CDS             4207..4395
                     /locus_tag="VYP30_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1808868.1"
                     /translation="MATDKNRIMISLDDKKLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4457..5215
                     /locus_tag="VYP30_001943"
     CDS             4457..5215
                     /locus_tag="VYP30_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1808869.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            5273..5734
                     /locus_tag="VYP30_001944"
     CDS             5273..5734
                     /locus_tag="VYP30_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1808870.1"
                     /translation="MLGVIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5768..6127
                     /locus_tag="VYP30_001945"
     CDS             5768..6127
                     /locus_tag="VYP30_001945"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1808871.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNVISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6239..7123
                     /locus_tag="VYP30_001946"
     CDS             6239..7123
                     /locus_tag="VYP30_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1808872.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7286..7990
                     /locus_tag="VYP30_001947"
     CDS             7286..7990
                     /locus_tag="VYP30_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1808873.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDSVAWVRQGIF"
     gene            7966..8421
                     /locus_tag="VYP30_001948"
     CDS             7966..8421
                     /locus_tag="VYP30_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808874.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNIIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         3059 a         1130 c         1750 g         2485 t
ORIGIN      
        1 tctatttaac ttcaattatt aggcaagctt taaaaaatac tgaatataaa gatcaaatat
       61 ctagcacagt attgccagat atcaaaatta aattaccgat agacagtaga ggtactccag
      121 attggaatta catggaaaga tatagagata gataaagaga gagagggaga gatagataaa
      181 aagtccaccc ccatttttta tggagaattc aaaaatgtaa ggttaagcaa agaagaatat
      241 aaaaatctaa aagaaaaatt aaactcacac acagatataa tgataaataa actatccaga
      301 tacatggaaa gcagtggtaa gacctatcaa aaccactatg tgacaatctt aaaatggtat
      361 gaagaagata aagacaaact aagacagaaa ggtttaaata aaaaaatgaa ttatgatgta
      421 ggagaatctt tatagataaa aagaggtgga aaggcactat taaagacttt aagtctaaaa
      481 aggtatcaaa gtatgccaga gataaaaaaa tataaatata acactttaaa ggcgattaga
      541 aaattaaaga aatgctagaa gacttttaga tgacagttac caagagggcc taattttcac
      601 tgctacttat gcagtgggaa tttgaccttt ttatataagc aaattctatt tcaaaattgg
      661 ttaccaagaa agacttcttt tcactgttaa gtataagagg gtaatttata gaattttgtt
      721 acattaagat aaatattttc tgatggtcaa attttaaaaa gattaataac tctcgataaa
      781 ttttgaacct taacaattga atagaccaag acaagacgtt aattattttt ggagcgtaat
      841 aacctatccg tcaagatctt tcggctgaat aattcggcaa aaaaagttct gctaagtaaa
      901 aagaaagtga gcgataagta agagtttgaa tatagggagg gataccctat ccgctatgaa
      961 gaaaatgagg ataatgatac ttctaaggtt gaagccggct catccggaat agaggcggag
     1021 gtgagattcc tatgttgcta atccaaagca cttgtcaatg tcaaaaaact taattaaaca
     1081 aataattatt agatataaaa ctttagagga ggtatatatt ggacaatgac tggaatggat
     1141 tggctgattt aatagcaaat ctgattgcaa aatatgctgg tgctttagat ttagataatc
     1201 tacccgatcc aacgccagca aaaaatcaag agatgaaaaa tagttttgac atggcaaaaa
     1261 cacaaattga gacggactaa taaaagtgtt ataatatact tgaaatgata gtccaaactt
     1321 aaattaaaaa aattatatat gatatagaaa aattatattg aggttaatac tatgtcaaaa
     1381 gaaaaaataa aagtatacct ctatacacga gtatctacgt caatacagat agaggggtat
     1441 tcgttagggg cacaaaaatc acgaatgaaa gcttttgcta tttacaacga ttatgaaatt
     1501 gttggagagt atgaagatgc cgggaagtct ggcaagtcta ttgaaggtag aatacagttc
     1561 aatcgaatga tggaagatat aaaatctgga aaagatggag tatcttttgt tcttgtgttt
     1621 aagttatcaa gatttgcaag aaatgccgct gatgttcttt ctacacttca gataatgcag
     1681 gattatggag ttaatcttat ctgcgttgaa gatggcattg attcatttaa agatgctggg
     1741 aaactaatga tttctgtttt atcagctgtg gctgaaatag aaagagaaaa catccgtatt
     1801 caaacaatgg aaggttgcat tcaaaaagca agggaaggaa aatggaatgg tggctttgct
     1861 ccgtatggat ataaacttga agacggcaag ctgtttataa atgaggaaga ggcagttgca
     1921 ataagaacga ttttcgacca gtatgtaaat actacgatag gagccaatgg gatatctaaa
     1981 tacttagaga atcatggaat tagaaaaatc ccaagacaga atggtaagaa tcctttgttt
     2041 gatgcaggtc ttataagaaa gatattaaag aatcctgtat ataatgggaa aatagcattt
     2101 ggaagaagaa ctttagaaaa agttcatggt acaagaaatg aatataagca ggttgaacaa
     2161 gatgaatatc taatatctga agggatacat gaagctatag tttccgatga agtttggcaa
     2221 gctgctcagg ttaagctaaa atctcaagca aagaaatatg agcgtgtgaa taaaggaaaa
     2281 gatacacgca cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg agtgggaatg
     2341 tttgggaaca agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga tttttattac
     2401 tatggttgta aacataggca gatgataaga ggtcatgagt gtacattcag taagcaaatt
     2461 agagaagaat tgttagatga tgctgttgca gaggtgattg tcaagatagt aagtaatccg
     2521 aaatttgctt ctatgatgca agaaaaaatc aacatgaagg tggatacctc tgaaatagaa
     2581 aaagaaatag ataattacca aaaggaattg agaaagagtc attctacaaa gtttaagcta
     2641 attgaggaaa tagataattt agatgttgaa gataagcatt ataagagaag gaaacaggat
     2701 ttagatgata gactatgtcg tatgtatgac aaaatagatg aattagaatc atcactaatt
     2761 gatgcgaaag caaagaaaca gactattgaa gctgaaaagc ttacaggaga taacatatat
     2821 aaggttctga tctattttga taagctctat aaagtcatga atgatgtaga gcataggcag
     2881 ttaatttcag ctttgatttc tgaaattcaa gtttatgaag aaaaacaatc taacggacaa
     2941 tggctaaaat ccattacttt taagctacca attatagaag aaaatctcaa cataggtttg
     3001 gataatgatg aacaagttga atgtgtaagt ttattagaga aacgtagtta atcctcaaaa
     3061 ggttccccaa accttttgag tcccactgac gcatcacgct gaggcggtat cactgcttgt
     3121 acgagttgaa gcatcagcga agtaaaagta gatgttcagc caatgcgacg aggtgagacc
     3181 gaaggtcgat aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga aatatgatga
     3241 gatgatacag agagcctgaa ttggtcaggt gacgtgctta tttacattag cctgataatg
     3301 aaaatggaga gattatcgat ggttatattg gaattgtacc aaaatgatta ttctaaagat
     3361 ttagtagcat ttgattccat agaagatggg aaagcctttg tagctcaaat cccgggatac
     3421 actctggaaa cagaagatgg ttttgaagtg gagtatttta atcctaaaaa cataccggat
     3481 tatatggaaa ttatttttaa cggaaatatt gttcctttat ctaaatttat gttcgatcct
     3541 gaggaaaatg taaacattat ttggaaagag atttcaaatt tatccctcaa aaatgataga
     3601 gtgatcgaag gatattcaaa aattgatgca tatgtcgtta acaaccatga agttaaagcc
     3661 tatgtcgaaa caagagaaac gaactatcgt aaagcaaaag acttcttaga aagccgcgga
     3721 tatgaaatcg acagaagctt tttcggaagt gaagacggtg aagcgattct ttacagaaaa
     3781 aaagggatcg aagtttggca tttcttgtgt cacttagacc caatgtttgt agagattgaa
     3841 gatgtagaag gatatgttaa agaagaagtt ggagagattc aatagtcaac caaagttcct
     3901 tgtgagtata tacctttgct agtaaaagag tcaaaacgtt ataacgaagg gggggaagaa
     3961 aacccttgag tgtaagtctt tttcttgttt agagggaaag tattagagta gccgctcata
     4021 atttatacta gatttgataa ctgatttgag acagatttta tttctataaa tattgtgaaa
     4081 attttttaat accaaagatt taaagttact gtgttaaaaa tcctctccac ttttaaacta
     4141 atgtattata aaagccagtt gacacaagtg ttacacctgt gatagaatta acttgaggtg
     4201 atgaaaatgg caaccgataa aaatagaata atgattagct tggatgataa aaaactagag
     4261 aaacttgaaa atttagtaga agatgctaga gatagaaggg gaatgcgact aacaaagtcc
     4321 caggttattg aattactcct aaataccgtt gattatttcg atgatattat gggagctatt
     4381 tactcaaaaa aataagagca aaattgctat tattttttac aaatcggtgt aacactagtg
     4441 atataggagt gatgaaatgg ttgtttatat tagacaaagt aaattaccaa gtgaggtttc
     4501 aattaataaa tacaatgctc aagtaggtgc ctacttacaa ggagaagaag ttattttata
     4561 tcaatctttt tctgaaataa aagagttaac aagtgaagat atagttgtag attatataat
     4621 ggagactaga gcattactaa aaatgatggg cttaaacgtt ccggtttatg actatcctat
     4681 tgagcttaaa gagttttatg gtcgaaagat ttatgctggt attttaggag agattgtgaa
     4741 tatacctgat aattggggaa aatttattaa gcctaaagct ggttcaaaag tctttactgg
     4801 aagagttgtt aatggaaccc atgatttaat aggtattggt ctacctttcg actatcctat
     4861 atggattagt gaggttgtag aattcatagc tgaatggcgt tgttttgtgt tagatggtcg
     4921 cgtattagat gttcgaccct atacaggtga ttatcatgca caatttgatg caagtgtaat
     4981 tgatgaagcg atatcatgtt ggaaagatgc gccaatagct tatggactag atatcggtgt
     5041 tactcgcgat ggcagaacac ttgttgttga agtaaatgat ggttatgcat tgggaaatta
     5101 tggcctatct cctttaaaat caatcaattt tcatagagct aggtggaaag aaatggtaaa
     5161 accctatttt gaaaaaaatg aaatttttaa aattcaacag gatgttattt tctaaaataa
     5221 atatggtaga taaccaatat aaaaagcatc aaaatgaaca aggaggaatc tgatgcttgg
     5281 agtaattatt ggagatattg tcggttctgt ttacgaatgg aacaatatca aaacaaagga
     5341 ctttccttta tttcggaagg actgcttttt tacagatgac acggttatga cctgtgctgt
     5401 tgcagaagca attatgaatg gtggacaaaa agacgacttc attgacgcga tgaagaaata
     5461 tggcagaatg tatccgaatg ctgattacgg tgctcggttt aatgcatggc taaacagcga
     5521 taaccgtgag ccttataata gctttgggaa tggatcagct atgcgtattt ctccatgtgc
     5581 ttggatcatg gactgtggtt tttatgcgaa aactggtata tggccatcat ctagaggact
     5641 tacgagtctt tctgcagagg taactcataa tcatccagaa ggtgtcaaag gcgctatggc
     5701 tacagctgat gctatctttc tatgtcgttt ttaatttggt ggttattgta gagagtacga
     5761 gtaatcaatt aacgacaatc ctatagagtg taaaagacga attaaggatt atatagaaaa
     5821 agaatacgat tacaatctat ctcaaacttt agatgaaatc cgtcctaact atcgttttaa
     5881 cgaaacatgt caggaaactg tccctcaagc cattatcgcc tttcttgaaa gtagagactt
     5941 cgaagatgcg ataagaaatg tcatctcact tggtggcgac agtgatactc tcgcagcaat
     6001 cacttgtagc atagcagagg cagcttacgg tattcctgat tggatcaagg ataaggccta
     6061 ttcttacttg gatgaaccct taaaggatgt agttaggcga tgggaaaata gaataaaagt
     6121 gtattaatct ccagtacgtc agatttctct tttctgtatt ttcattgtat aataggatta
     6181 catttacttg catacgacga aatgtaaaca tttctgttta aaattaagga taaaatcaat
     6241 gaaaaaagca atggtaatta tcaaccctac ttctggtggc gagaaggctt tggattacaa
     6301 agaaaagctg gagaataaag caaaagaata ctttgaatat gttgaaacca aaattaccga
     6361 aaaagcgctg gatgcaacac attttgctga agaagcttct cgtgagcagt atgatgcagt
     6421 ggttgtgttt ggtggagatg gaactgtcaa tgaagtcatt tcaggtattg atgagagaga
     6481 ctacattcct aagttaggga ttatcccagg cggtacaggt aacctcatta caaaactttt
     6541 ggaaatcaat caagacatcg atggcgcaat tgacgaactg gattttgatt taaccaataa
     6601 gattgatatc ggtaaagcaa atgacaacta ttttggttat atctttagta tcggttctct
     6661 gcctgaggcg attcacaatg ttgaaataga ggacaaaaca aaattcggta ttttaaccta
     6721 tgctgtaaat accatgaagt ctgtcatgac agatcaggtc tttaacatta aggttgagac
     6781 agaaaatgga aattatgttg gtgaagctag ccatgttttg gtccttttga caaattactt
     6841 cgctgataag aaaatctttg aagaaaacaa ggacggctat gccaacattt tgattctgaa
     6901 agatgcctct atattctcca aattatccgt cattcctgat ttattaaaag gggatgttgt
     6961 cgcaaatgat aatatcgagt atatcaaagc gcgtaatatt aaaatctctt cagatagtga
     7021 attggagtca gatgttgacg gagataaatc agataaccta cctgtagaaa tcaaagtcct
     7081 agctcagcga gtagaagtat tttcaaaacc gaaagaggat tagtatatag agaaagcctt
     7141 ttttaaggct ttttgtatac tttaaaagat agttccttta acaacggaca ttccttgcaa
     7201 atagtttaca aaaatagtat actggattta ttgagtttga aaacgtttgc gtaaaatttg
     7261 aatgaatact ttaggagaca aattgatgga attgagtgct atttaccata ggcctgagtc
     7321 ggagtatgcc tatctttata aggataagaa actccatatt cgaattcgaa ctaagaaagg
     7381 ggacattgaa agcatcaact tgcactatgg ggaccctttt atctttatgg aggagtttta
     7441 tcaggataca aaagaaatgg tcaagataac ttctggtacc ttatttgacc attggcaggt
     7501 tgaagtgtca gttgactttg cacgtatcca gtatctcttt gagctcagag atacagaagg
     7561 tcaaaatatt ttgtatggcg ataaagggtg tgtggaaaat tctctagaaa atcttcatgc
     7621 aattgggaat ggatttaagt tgccttatct tcatgagatt gatgcctgca aggttcctga
     7681 ctgggtttca aatacggtat ggtatcagat atttcctgaa agatttgcca atggcaatgc
     7741 tctattaaac ccagaaggga ctttagactg ggattcatct gtcacaccta agagcgatga
     7801 tttctttggt ggtgatttac aggggattat tgatcatatg gattacttgc aagacttggg
     7861 tattactgga ctatatcttt gtcccatctt tgaatctaca agcaatcaca agtacaatac
     7921 gacagattac tttgaaattg accgtcattt tggagacagt gttgcatggg tgcggcaagg
     7981 gattttttag aactaattaa tcacaaaggg ctacctcttt ttaatccgct tgtaggtgat
     8041 tctcatgtaa ataatagaca agaatatgac aatacaggga gtggaaattt acaacctgaa
     8101 aagtggaatg aaactgcaaa gcagctttat aatattataa tgtggttgat tattttatgg
     8161 aatgctaagc cggatacacc tttatttaat tttaaagacg aagtaattaa gtataaaaca
     8221 tatgagcctt ttgaaagcag tataaaaaga gtaaatacta ctataaagaa tggtagtaaa
     8281 gggaaaactc tgactgagat gattaatggc tacagagcgg ataacgatat tagagatgaa
     8341 atttgtaact ttaatattct gaaaaataaa attcgtgata tgaaagacca acaaggaaat
     8401 acaatggaat cttactttta gtta
//
LOCUS       DAVMBH010000069         8355 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVMBH010000069 DAVMBH010000000
VERSION     DAVMBH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8355
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.069"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..273
                     /locus_tag="VYP30_001949"
     CDS             <1..273
                     /locus_tag="VYP30_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV1808875.1"
                     /translation="VIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELSTNIEKKIM
                     NYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            286..1761
                     /gene="galT"
                     /locus_tag="VYP30_001950"
     CDS             286..1761
                     /gene="galT"
                     /locus_tag="VYP30_001950"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1808876.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEENAIADYHLEWADQLKEKYPRINKEEVN
                     NVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1774..2784
                     /gene="galE"
                     /locus_tag="VYP30_001951"
     CDS             1774..2784
                     /gene="galE"
                     /locus_tag="VYP30_001951"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1808877.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2964..3623
                     /locus_tag="VYP30_001952"
     CDS             2964..3623
                     /locus_tag="VYP30_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1808878.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3648..4715
                     /locus_tag="VYP30_001953"
     CDS             3648..4715
                     /locus_tag="VYP30_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1808879.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4819..5829
                     /locus_tag="VYP30_001954"
     CDS             4819..5829
                     /locus_tag="VYP30_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808880.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDEIVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5841..7532
                     /locus_tag="VYP30_001955"
     CDS             5841..7532
                     /locus_tag="VYP30_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1808881.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7535..8245
                     /locus_tag="VYP30_001956"
     CDS             7535..8245
                     /locus_tag="VYP30_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1808882.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2832 a         1154 c         1647 g         2722 t
ORIGIN      
        1 gttatcggac tgcatatgaa tagggctata tcttgttata gagaggaaca atctggatgt
       61 ttagatatgg ttgttataca aaaacagaat gagatagaag agcttagtac aaatattgaa
      121 aagaaaataa tgaattacat atttgaagat gatgggaatg tttctgaagt aattggtgct
      181 ttagatatta ttcatcacct tgataaaatt gctcatacta cgcaatcaat ttataaatgg
      241 ataatgtata gaaaatatgg gaacataaat tagaaagaaa aatatatgaa aacaattatt
      301 gataattttg ttgatagagt aattgaatac ggaatgtata atgaaattga caaaatatat
      361 gtgaaaaata gagtactagc gttaataggt gaggagggaa ctgatcgcat ttccgatgaa
      421 aatgacctga aacaaataaa agattactta gtggaaatcg ccttaaaaaa cggtaaaatt
      481 aaagatttaa tcgaggaaaa ggaatgttta ggagcagagt taatgaattt catagttcct
      541 ttacctagtc gattaaatga tattttttgg agttcatatg atatatcacc tcaagaagca
      601 gttgaagagt tttataagtt aagtaaagat agtgattata ttaaaacttc tgctattgct
      661 aagaatattg agtttcgagc atcaactaaa tacggagagc tagagattac gataaatttg
      721 tcaaaacccg aaaaagatcc aaaaacaatt gctgctgaaa aattagtaaa agccactaat
      781 tatcccaaat gtttactatg tatggaaaat gaaggatatc aggggcgaat aaattatcca
      841 gcacgttcga atcatagaat tattcgattg aaacttggtg acgaagtatg gggattccaa
      901 tattctccct acttatactt taatgagcat gcgatatttt taaatagtca acatgtacca
      961 atggctatta cctctaaaac atttgaacaa ttattggaga ttgttgatat tttgccagga
     1021 tattttgctg gttcaaattc tgatcttcct atctcaggag gctccattct tagtcataac
     1081 cactaccagg gagggaaaca tattttccca atggaaaaag caaaatttga gagtgaattt
     1141 cgttttaaag actttgagga tgttaatgct ggtattgtaa aatggccaat gtcagtaatt
     1201 aggttacaaa gtgaaaataa aaatcgcttg ttagatttag ctactaaaat tctaaataag
     1261 tggagagaat attcagattt agaagtagac atcattgcta tgactgaaga tgtcccacac
     1321 catacggtga ctcctattgc tcgtaaagtg gacgggagat atgaattaga tattgttcta
     1381 agagataatc atactactga acagtaccca gatggtgttt tccatcctca tcaagatgta
     1441 caacatatta aaaaggaaaa tatcgggtta atcgaagtga tgggacttgc gatattacca
     1501 cctcgtttga aaccagagtt agaagaagtg ggaaaatatc ttttaggaga ggaaaacgca
     1561 attgcggatt atcatttaga atgggccgac caattgaaag aaaaatatcc tcgcattaat
     1621 aaagaagagg ttaataacgt agttcaacac gaagcaggac aagtgtttgc gagagttctg
     1681 gaagatgcag gagtttataa gaatacaccg tctgggcatg aagcgtttat gagatttgtt
     1741 aagtcggttg gaattaatta ggaggaaacc caaatggcaa tattggtaac aggcggagct
     1801 ggttatattg gtagccatac cgtagtagaa ttactaaatt taggaaagga agtcatcatt
     1861 gtcgacaacc tttcgaactc tagcatcttg gtgctagacc gtattgaagc aattacagga
     1921 atacgtcccg tgttttacga attagatgtt tgtgataaac aagcattgag aaaggtattt
     1981 gaacaagaat cgattgatgc tgcaattcat tttgcaggtt ataaagctgt cggagaatcc
     2041 gtgcaaaagc ctgtgatgta ctacaaaaat aatattatga gtacattggc acttgttgaa
     2101 gtgatgtcag aatttaatgt taaaaagatt gtcttttctt caagtgcgac tgtatatgga
     2161 attaacaatc agtcacctct aattgagacg atgcaaacaa gtgcgacaaa tccttatggg
     2221 tatacgaaag tgatgcttga gcaaatttta aaagatgttc atgtggcaga ttcagaatgg
     2281 agtattgcgt tgcttcgtta tttcaatcca attggtgctc atgagtctgg tttgattggg
     2341 gaagatccct caggaattcc taacaacttg atgccttata ttgcacaagt agcggtaggt
     2401 aagctatcag agctaagtgt gttcggaaat gattatgata cgcttgatgg tactggtgtg
     2461 cgtgattata tccatgtagt agatttagca ataggacata taaaagcttt agaaaaagta
     2521 tctgaaaaaa cagatgttta tatctataac ctaggctcgg gagaaggcac tagtgtatta
     2581 caacttgtaa atacatttga aagtgttaat aagatcccta ttccttataa aatagttcca
     2641 agacgttcag gagacgttgc aacttgttat gcaaatgcag acaaagcata taaggaatta
     2701 aattggagga caacaaaatc gattgaagac atgtgtagag atacatggaa ttggcaatca
     2761 aaaaatccca atggctataa ttgatgatac tgtctatatg agtgctgtat tttgaaaaaa
     2821 ttacttaacc ttttaatgaa atgcatattt aatgaaagat aaatttaaaa aaatgtttgc
     2881 aagtgcttga caaaggaaac ggtttcattg tataatgtaa acatgatgac accgatgtca
     2941 aatataaaaa agaaggtctt tatatgaaaa acttaacaaa aattaagttc aaagagaatg
     3001 gggaatttaa tcatttccct gggaatacag ttgtagcaaa tctttatact aaacaagatt
     3061 tgatggaagt tgttgatatt attcaatcac gttatagaga attaccattt atcgataagt
     3121 ttactttaac tccaaggaat tctattcaca tgactgtaat tgaattgttg tgccatgaaa
     3181 atcgtgaaac ggagttttgg agcagtaatc ttcctctaga tacaccttta caggaaatac
     3241 atgattactt tgctaaacaa cttgaaattt ttccattgtt ggatgaagaa attcatatgc
     3301 gtataactga aatgggaaaa caaaacatac tagttgaacc tgcagatgaa gcttctgcaa
     3361 agagattaga agaaattcgt acttatgtct cagaaaaagc aggtgtttgt ttccctaatc
     3421 atgatagata tcaattccat atttcaattg ggtatcttcg gattcctcta accgaagagg
     3481 aggaagaaga gtttactaaa gtcagagcag aattaactga aattttatta gagaagattc
     3541 caactattac tgtaaaccgt attgactata ctgtatttga agatatgaga caatttgttc
     3601 catatcacga aaaatttaaa taaaataata aaaaaggaga acttatcatg aaaaaaatga
     3661 aagtttggtc tactgtactt gcaacgggag ttgctcttac tacacttgct gcttgctctg
     3721 gaggttcaaa ttctacgact gcttcttcat ctgaagaaaa agctgataaa agtcaagaat
     3781 tagttatcta ttcgaactca gtctcaaatg gtcgtggtga ttggttaact gctaaagcaa
     3841 aagaagctgg ttttaatata aaaatggttg atatcgctgg cgctcaatta gcagaccgtg
     3901 ttattgctga gaagaataat gcagttgcag atatggtatt tggaattggt gctgttgatt
     3961 caaataaaat tagagatcaa aaattactag tacagtacaa gcctaaatgg ttagataaaa
     4021 ttgatcaatc tttatcagat aaagataatt attataatcc tgtgattgtt caaccattag
     4081 ttttaattgg ggcgcctgat gtaaaagaaa tgcctaaaga ttggactgaa ttaggtagta
     4141 agtataaagg taaatattca atttatggtc ttcaaggtgg tacaggacgg gcaattctag
     4201 caagtatctt agttcgttac cttgatgaaa aaggagattt aggcgtatca gaaaaaggat
     4261 gggaagttgc aaaagaatac tttgcaaatg cctatactct tcaaaaaggt gaaagctcag
     4321 ttgttaaagc gttagataaa gaaagcccaa ttcaatacgg tatgatctgg ggttctggag
     4381 cgttaattgg acaaaaagaa caaaatgttg aattcaaagt tatgactcct gagattggtg
     4441 taccatttgt aactgaacaa actatggttt taagcactag taaaaaacaa gcgttagcta
     4501 aagaatttat tgattggttt ggtcaatcag aaattcaagt agaatatagt aaaaaatttg
     4561 gatctattcc tgccaataaa gatgccctaa aagagttacc tgaagatacg aaaaaatttg
     4621 ttgatcaagt gaaaccacaa aatattgact gggaagctgt tggaaagcat ttggatgaat
     4681 gggtagaaaa agctgaatta gaatacgtaa aataagaaat aagagttatt ttttatgtcc
     4741 aagtctctct attatttcta aatttaagga agaaataaag agaggctttt ggttttagta
     4801 atagagggag ttagtgagat gattaaattt gataatattc aaattaaata tggtgatttt
     4861 gttgcaattg ataatctgaa tttagatata catgaagggg aattctttac atttcttggg
     4921 ccttcaggat gtggtaaatc aactactttg agagcattgg taggtttttt agatccatca
     4981 tcaggaagta ttgaagttaa tggaacagat gtcactcatt tggaacctga aaagcgtgga
     5041 attggtattg tatttcaatc ttatgcgcta tttccaacta tgactgtttt tgataatatt
     5101 gcatttggtt taaaagttaa gaaggtagct ccagatgtta ttaaagctaa agtatcagca
     5161 gtggcagcaa aaattaagat ctctgatcaa cagttacagc gtaatgtatc agaattatct
     5221 gggggtcaac aacaaagggt agcattggct cgtgctctgg ttcttgaacc taaaattctt
     5281 tgtctagatg aaccattgtc aaaccttgac gcaaaattac gtgtagattt gagaaaagag
     5341 ttgaaaagac ttcaaaaaga gttaggtatt actactttat atgttactca tgatcaagag
     5401 gaagccttga ctttatctga tagaattgca gtctttaaca atggatacat cgaacaggtc
     5461 ggtacaccag tagagattta tcataattct caaactgaat ttgtatgtga tttcattgga
     5521 gatattaatg ttttgaccga tgaaatagtc cacgaagtat tattgaaaaa tacaagcgtt
     5581 ttcttagagg ataaaaaagg atacattcga ttagagaaag ttcgattcaa tcgtgaaact
     5641 gaacaagatt ttattctaaa agggacaatt attgatgttg agttttctgg agttacaatt
     5701 cactatacaa taaaagtttc tgaaagtcag attcttaatg taacaagtat tgatagtcag
     5761 gctgctatta gatctgtcgg agaaagtgtg gaattattta tcacaccatc agacgttctg
     5821 caattttaag gaggtgcagt atgcgtcata aattaaattt aaaagattgg cttattcgtt
     5881 tagggttaat ctggttctta gtaacattta ttatttatcc aaactttgat ctagtagtga
     5941 atgtatttgt aaaaggagga gaattttccc ttgatgctgt acatcgtgtt ctaaaatctc
     6001 agagggcact tcagagtatt atgaacagtt ttaagttagc attttcactc attattacag
     6061 ttaatgtcgt aggtattctt tgtgttctat ttacagagta ctttgatatt aaaggtgcta
     6121 aaattttaaa attaggttat atgacctctt taatttatgg aggagtggtt ttagcgactg
     6181 gatataaatt tgtctatggt ccttatggat tgattacaaa atttttacaa aatgttatcc
     6241 cttctttaga ctctaactgg tttattgggt atggtgcagt cttattcatt atgacatttt
     6301 caggaactgc taatcataca ttgtttttaa caaatacaat tcgaagcgtt gactatcaca
     6361 ctattgaggc tgctcgaaat atgggagcaa aaccatttac tgttttccga aaagtagtgt
     6421 taccaacctt aattccaact ctatttgcac ttactattat ggtttttctt agtggtttat
     6481 ctgcagtagc agcacccatg attgttggtg gtaaagaatt tcaaactata aatccaatga
     6541 ttattacatt tgcagggatg gggaattctc gtgatttagc tgccttactt gcaattattt
     6601 taggtattgc aactacaatt ttgcttacta tcatgaataa gatagaaaaa ggtggaaatt
     6661 atatttctat ctctaagact aaagcgcctc ttaaaaaaca aaaaattgcg tctaagcctt
     6721 ggaatatcat tgctcacatt gtagcatatg gattgttcac agttttcatg cttccactaa
     6781 tttttatagt attatactca tttacagatc cagttgcaat tcaaacaggt aacttaacat
     6841 tatcaaactt tactttagaa aattatcgct tattctttag taatagtgcg gcattctctc
     6901 cattcttggt cagctttatt tattctatta ttgctgcgac aacagcaaca attctcgcag
     6961 ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt tgatttctta tttgaatatg
     7021 gtgctctact tccttggtta ctaccaagta cacttttagc agtaagttta ttatttactt
     7081 ttaatcagcc acaatttctt gtcttgaatc agattttggt aggtagtttg gtaattctac
     7141 ttattgcata tatagttgta aaaatcccat tttcttatag aatggtacgt gctattttat
     7201 ttagtgttga tgatgagatg gaagatgcag caagaagtat gggtgcttca cctttttata
     7261 ctatgatgaa ggttatcatt ccatttattt taccggttgt tctctctgtt attgctttaa
     7321 actttaactc tttattaact gacttcgact tatctgtatt cctttaccat cccctagctc
     7381 aaccattagg tattacgatt cgatctgcag gtgatgaaac agcaacatct aatgcacaag
     7441 ctctggtatt tgtttataca attgttctga tgattatttc tggaacggta ttatacttca
     7501 cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca gccactagtc ttgggttatc
     7561 aaatattgaa atagttgtca ggattgtttt atcagtagtc attggtagta taattggttt
     7621 agagagaggg agcaaatccc agcctgcagg catccgaact tatagtattg tttgtctagc
     7681 tgcatgtttg attatgatga cgaatgaata cgtatcttat aaatttggga caggagatcc
     7741 tacacgatta ggagctcaag ttatatcagg tgtgggtttt ctaggcgctg gaacgattct
     7801 tattacagat aaaaagaaaa ttacaggtct gacaactgca gcaggcattt gggcttcggc
     7861 aggaattgga ttagctattg gagtaggttt ttatgaggga gctcttttag tagccatttc
     7921 tgtttggggt gtgatatcca tgttccaacc actaaaaaaa tatctgcaaa atcgttctaa
     7981 aatgattgaa ttgtatatag tggttaaatc tacagaagcc tataatcgtg tattggttta
     8041 ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca gcgtttggag atgttaattc
     8101 tgacagaatt gaatactttg atgttccgga caaaaaaata gcgtcattta ttactctgga
     8161 attatcaggt agatttgaac atcttcgact gatggaagaa attgctaata ttgtaggtgt
     8221 tatttatgtc gaagaaatta gctgaaattt agtaaacaaa gggacagatg tttttgtcct
     8281 tttgcttttt agatgtttta atcatctaat ttttgagtag atttttgctc agaggttttt
     8341 atgaaagatt ataaa
//
LOCUS       DAVMBH010000070         8044 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVMBH010000070 DAVMBH010000000
VERSION     DAVMBH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.070"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            200..2182
                     /locus_tag="VYP30_001957"
     CDS             200..2182
                     /locus_tag="VYP30_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1808883.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2482..7785
                     /locus_tag="VYP30_001958"
     CDS             2482..7785
                     /locus_tag="VYP30_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1808884.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENHSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTAESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKSDAPTVEKPEFKLSSLASEQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
BASE COUNT         2644 a         1525 c         1755 g         2120 t
ORIGIN      
        1 aatctccaga ttaggaacta tccgtgagtt ctctagtctg gagatttttc aatatacttc
       61 gttattgggc gcttacaatg atattcatat tttttgcaaa gatgttgttt gaaaaataat
      121 tttcaaaaat tctgaaaatt ctgttgacaa ctttctgaaa agagtctata atggagagaa
      181 agttttaaag gagaaaatga tgaaaagttc aaaactattt gcccttgcgg gcgtgacatt
      241 attggcggcg actactttag ctgcatgctc tggatcaggt tcaagtacta aaggtgagaa
      301 gacattctca tacatttatg agacagaccc tgataacctc aactatttga caactgctaa
      361 ggctgcgaca gcaaatatta ccagtaacgt ggttgatggt ttgctagaaa atgatcgcta
      421 cgggaacttt gtgccgtcta tggctgagga ttggtctgta tccaaggatg gattgactta
      481 cacttatact atccgtaagg atgcaaaatg gtatacttct gaaggtgaag aatacgcggc
      541 agtcaaagct caagactttg taacaggact aaaatatgct gctgataaaa aatcagatgc
      601 tctttacctt gttcaagaat caatcaaagg gttggatgcc tatgtaaaag gggaaatcaa
      661 agatttctca caagtaggaa ttaaggctct ggatgaacag acagttcagt acactttgaa
      721 caaaccagaa agcttctgga attctaagac aaccatgggt gtgcttgcgc cagttaatga
      781 agagtttttg aattcaaaag gggatgattt tgccaaagct acggatccaa gtagtctctt
      841 gtataacggt ccttatttgt tgaaatccat tgtgaccaaa tcttctgttg aatttgcgaa
      901 aaatccgaac tactgggata aggacaatgt gcatattgac aaagttaaat tgtcattctg
      961 ggatggtcaa gataccagca aacctgcaga aaactttaaa gatggtagcc ttacagcagc
     1021 tcgtctctat ccaacaagtg caagtttcgc agagcttgag aagagtatga aggacaatat
     1081 tgtctatact caacaagact ctattacgta tctagttggt acaaatattg accgtcagtc
     1141 ctataaatac acatctaaga ccagcgacga acaaaaggca tcgactaaaa aggctctctt
     1201 aaacaaggat ttccgtcagg ctattgcctt tggttttgat cgtacagcct atgcctctca
     1261 gttgaatgga caaactggag caagcaaaat cttacgtaat atctttgttc caccaacatt
     1321 tgttcaagca gatggtaaaa actttggcga tatggtcaaa gagaaattgg tcacttatgg
     1381 ggatgaatgg aaggatgtta atcttgcaga ttctcaggat ggtctttaca atccagaaaa
     1441 agccaaggct gaatttgcta aagctaaatc agccttacaa gcagaaggtg tgactttccc
     1501 aattcatttg gatatgccag ttgaccagac agcaactaca aaagttcagc gcgtccaatc
     1561 tatgaaacaa tccttggaag caactttagg agcggataat gtagtcattg atattcaaca
     1621 actacaaaaa gacgaagtaa acaatattac atattttgct gaaaatgctg ctggcgaaga
     1681 ctgggattta tcagataatg tcggttgggg tccagacttt gccgatccat caacctacct
     1741 tgatatcatc aaaccatctg taggagaaag tactaaaaca tatttagggt ttgactcagg
     1801 ggaagataat gtagctgcta aaaaagtagg tctatatgac tacgaaaaat tggttactga
     1861 ggctggtgat gagactacag atgttgctaa acgctatgat aaatacgctg cagcccaagc
     1921 ttggttgaca gatagtgctt tgattattcc aactacatct cgtacagggc gtccaatctt
     1981 gtctaagatg gtaccattta caataccatt tgcattgtca ggaaataaag gtacaagtga
     2041 accagtcttg tataaatact tggaacttca agacaaggca gtcactgtag atgaatacca
     2101 aaaagctcag gaaaaatgga tgaaagaaaa agaagagtct aataaaaagg ctcaagaaga
     2161 tctcgcaaaa catgtgaaat aactgttgca aaatataaga aaggatttag tatttctctt
     2221 gaatgctgaa tcctttttta catttgtaaa gaaagattct aaatgtactg acccccaaaa
     2281 gttggagcct ctttttgtca gaatagagaa aatttttgtt aattttactt gtttcctatt
     2341 gctttctcag ttattatttg ttatattaaa agtataatta tttttattta tcagggttaa
     2401 gcattgcact ttcagaggaa ggagtatttt ttaaaaagaa aatgtaaacg cttgctaaaa
     2461 aatgaaagga tttagaagtt tatgaataaa ggattatttg aaaaacgttg taaatatagt
     2521 attcggaaat tttcattagg tgttgcttct gttatgattg gagctgcatt ctttgggaca
     2581 agtccggttc ttgcagatag cgtgcagtct ggttccacgg cgaacttacc agctgattta
     2641 gctactgctc ttgcaacagc aaaagagaat gatgggcgtg attttgaagc gcctaaggtg
     2701 ggagaagacc aaggttctcc agaagttaca gatggaccta agacagaaga agaactatta
     2761 gcacttgaaa aagaaaaacc ggctgaagaa aaaccaaaag aggataaacc tgcagctgct
     2821 aaacctgaaa cgcctaagac ggtaacccct gaatggcaaa cggtagagaa aaaagaacaa
     2881 cagggaacag tcactatccg agaagaaaaa ggtgtccgct acaaccaact atcctcaact
     2941 gctcaaaatg ataacgcagg taaaccagcc ctgtttgaaa agaagggctt gaccgttgat
     3001 gccaatggaa atgcaactgt tgatttaacc ttcaaagaag attctgaaaa gggcaaatca
     3061 cgctttggtg tcttcttgaa atttaaagat accaataata atgtttttgt cggttatgac
     3121 aaggatggct ggttctggga gtataaatct ccaacaacta gcacttggta tagaggtagt
     3181 cgtgttgctg ctcctgaaac aggatcaata aaccgtctct ctatcactct caagtcagac
     3241 ggtcagctaa atgccagcaa taacgatgtc aatctctttg acacagtgac tctaccagct
     3301 gcggtcaatg accatcttaa aaatgagaag aagatccttc tcaaggcagg aacttatggc
     3361 aatgaccgta cggttgtcag cgttaaaacg gataaccaag agggggtaaa aacagaggat
     3421 acccctgctg aaaaagaaac aggtcctgaa gttgatgata gcaaggtgac ttatgacacg
     3481 attcagtcta aggtcctcaa agcagtgatt gaccaagcct tccctcgtgt caaggaatac
     3541 agcttgaacg ggcatacttt gccaggacag gtgcaacagt tcaaccaagt ctttatcaat
     3601 aaccaccgaa tcacccctga agtcacttat aagaaaatca atgagacaac agcagagtac
     3661 ttgatgaagc ttcgcgatga tgctcactta atcaatgcgg aaatgacagt acgcctgcaa
     3721 gttgtggaca atcaattgca ctttgatgtg accaagattg tcaaccacaa tcaagtcact
     3781 ccaggtcaaa agattgatga cgaaagaaaa ctactttctt ctattagttt cctcggcaat
     3841 gctttagtct ctgtttctag tgatcaaact ggtgctaagt ttgatggggc aaccatgtca
     3901 aacaatacgc atgtcagcgg agatgatcat atcgatgtaa ccaatccaat gaaagaccta
     3961 gccaagggtt acatgtatgg atttgtttct acagataagc ttgctgctgg tgtttggagt
     4021 aactctcaaa acagctatgg tggtggttcg aatgactgga ctcgtttgac agcttataaa
     4081 gaaacagtcg gaaatgccaa ctatgtagga atccacagct ctgaatggca atgggaaaaa
     4141 gcttataaag gcattgtttt cccagaatac acgaaggaac ttccaagtgc taaggttgtt
     4201 atcactgaag atgccaatgc agacaagaac gttgattggc aagatggtgc cattgcttat
     4261 cgtagcatta tgaacaatcc tcaaggttgg gaaaaagtta aggatatcac agcttaccgt
     4321 atcgcgatga actttggttc tcaagcacaa aacccattcc ttatgacctt ggatggtatc
     4381 aagaaaatca atctccatac agatggtctt gggcaaggtg ttctccttaa aggatatggt
     4441 agcgaaggcc atgactctgg tcacttgaac tatgctgata ttggtaagcg tatcggtggt
     4501 gtcgaagact tcaagaccct aattgagaag gctaagaaat atggagctca tctaggtatc
     4561 cacgttaacg cttcagaaac ttatcctgag tctaaatact tcaatgaaaa aattctccgt
     4621 aagaatccag atggaagcta tagctatggt tggaactggc tagatcaagg tatcaacatt
     4681 gatgctgcct atgacctagc tcatggtcgt ttggcacgtt gggaagattt gaagaaaaaa
     4741 cttggtgacg gtctcgactt tatctatgtg gacgtttggg gtaatggtca atcaggtgat
     4801 aacggtgcct gggctaccca cgttcttgct aaagaaatta acaaacaagg ctggcgcttt
     4861 gcgatcgagt ggggccatgg tggtgagtac gactctacct tccatcactg ggcagctgac
     4921 ttgacctacg gtggctacac caataaaggt atcaacagtg ccatcacccg ctttatccgt
     4981 aaccaccaaa aagatgcttg ggttggggac tacagaagtt atggtggtgc agccaactat
     5041 ccactgctag gtggctacag catgaaagac tttgaaggct ggcaaggaag aagtgactac
     5101 aatggctatg taaccaactt atttgcccat gacgtcatga ccaagtattt ccaacacttc
     5161 actgtaagca aatgggaaaa tggtacaccg gtgactatga ccgataacgg tagcacctat
     5221 aaatggactc cagaaatgcg agtggaattg gtagatgctg acaataataa agtagttgta
     5281 actcgtaagt caaatgatgt caatagccca caatatcgcg aacgtacagt aacgctcaac
     5341 ggacgtgtca tccaagatgg ttcagcttac ttgactcctt ggaactggga tgcaaatggt
     5401 aagaaacttt ctactgataa ggaaaaaatg tactacttca atacgcaggc tggtgcaaca
     5461 acttggaccc ttccaagcga ttgggcaaag agcaaggttt acctttacaa gctaactgac
     5521 caaggtaaga cagaagagca agaactaact gtaaaagatg gtaaaattac cctagatctt
     5581 ctagcaaatc aaccatacgt actttaccgt tcaaaacaaa ccaatcctga aatgtcatgg
     5641 agtgaaggca tgcacatcta tgaccaagga tttaatagtg gaaccttgaa acactggacc
     5701 atttcaggcg atgcttctaa ggcagaaatt gtcaagtctc aaggggcaaa cgatatgctt
     5761 cgtattcaag gaaacaaaga aaaagttagt ctcactcaga aattaactgg cttgaaacca
     5821 aataccaagt atgccgttta tgtcggtgtc gataaccgta gtaatgccaa ggcgagcatc
     5881 actgtaaata ctggtgaaaa agaagtgact acttatacca ataagtctct cgcgctcaac
     5941 tatgttaagg cttacgccca caatacacgt cgtgacaatg ctacagttaa cgatacaagt
     6001 tacttccaaa acatgtacgc cttctttaca acaggatcgg acgtctcaaa tgttactctg
     6061 acattgagtc gtgaagctgg tgatcaagca acttactttg atgaaattcg tacctttgaa
     6121 aaccattcaa gcatgtatgg agacaagcat gatacaggta aaggcacctt caagcaagac
     6181 tttgaaaatg ttgctcaggg tatcttccca tttgtagtgg gtggtgttga aggtgttgaa
     6241 gataaccgca ctcacttgtc tgaaaaacat gatccatata cacaacgtgg ttggaacggt
     6301 aagaaagttg atgatgttat cgaaggaaat tggtcactca agacaaatgg actagtgagc
     6361 cgtcgtaact tggtttacca aactattccg caaaacttcc gttttgaagc aggtaagacc
     6421 taccgtgtaa cctttgaata cgaagcaggt tcagacaata cctatgcttt tgtagtcggt
     6481 aagggagaat tccagtcagg tcgtcgtggt actcaagcaa gcaacttgga aatgcatgaa
     6541 ttgccaaata cttggacaga ttctaagaaa gccaagaagg caaccttcct cgtgacaggt
     6601 gcagaaacag gggatacttg ggtaggtatc tactcaactg gcaatgcaag taatactcgt
     6661 ggtgattctg gtggaaatgc caacttccgt ggttataacg acttcatgat ggataatctt
     6721 caaatcgaag aaattaccct aacaggtaag atgttgacag aaaatgctct gaagaactac
     6781 ttgccaacgg ttgccatgac taactacacc aaagagtcta tggatgcttt gaaagaggcg
     6841 gtctttaacc tcagtcaggc cgatgatgat atcagtgtgg aagaagcgcg tgcagagatt
     6901 gctaagattg aagccttgaa gaatgctttg gttcagaaga aaacggcttt ggtagcagat
     6961 gactttgcaa gtcttacagc tcctgctcag gctcaagaag gtcttgcaaa tgcctttgat
     7021 ggaaacttat ctagtttatg gcatacatca tggggcggag gagatgtagg caagcctgca
     7081 accatggtct tgaaagaagc aactgaaatc actggacttc gttatgttcc acgtggatca
     7141 ggttcaaatg gtaacttgcg tgatgtgaaa cttgttgtga cagctgagtc tggcaaggag
     7201 cataccttta ctgcaactga ttggccagat aacaataagc caaaagacat tgattttggt
     7261 aagacaatta aggctaagaa aattgtcctt acaggtacta agacttacgg agatggtggc
     7321 gataaatacc aatctgcagc ggaacttatc tttactcgtc cacaggtagc agaaacacct
     7381 cttgacttgt caggctatga agcagctttg gctaaggctc agaaattaac agacaaagac
     7441 aatcaagagg aagtagctag cgttcaggca agcatgaaat atgcgacgga taaccatctc
     7501 ttgacggaaa gaatggtgga atactttgca gattatctca accaattaaa agattctgct
     7561 acgaaatcag atgctccaac tgtagagaaa cctgagttta aacttagctc tttagcttcc
     7621 gaacaaggta agacgccaga ttataagcaa gaaatagata gaccagaaac acctgaacaa
     7681 atcttgccag caacaggtga gagtcaatct gacacagccc tcttcctagc aggtgttagc
     7741 ctagccctat ctgctctctt tgtagtaaaa acgaagaaag actagtattt agtaaaacct
     7801 cttaacaaga ttacggaagc agtctctatc ttttccaatg aggtttatag tacagaaaaa
     7861 gcctgagaag atgtcttctc aggcttttgt taagcacata aatacaatag tgctatgaaa
     7921 aaatcaccca gaaaaatctg gctctataat atctatagtg ggtaaatcca ctatagatat
     7981 tatggagcct attttattgt agaaaaaaag tcccatatga cctataatga aaagcgacaa
     8041 aacc
//
LOCUS       DAVMBH010000071         8012 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVMBH010000071 DAVMBH010000000
VERSION     DAVMBH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.071"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(718..1710)
                     /locus_tag="VYP30_001959"
     CDS             complement(718..1710)
                     /locus_tag="VYP30_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808885.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     ILNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1870..3624
                     /locus_tag="VYP30_001960"
     CDS             1870..3624
                     /locus_tag="VYP30_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808886.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3608..5329
                     /locus_tag="VYP30_001961"
     CDS             3608..5329
                     /locus_tag="VYP30_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808887.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5340..5924
                     /locus_tag="VYP30_001962"
     CDS             5340..5924
                     /locus_tag="VYP30_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1808888.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     YMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5924..6619
                     /locus_tag="VYP30_001963"
     CDS             5924..6619
                     /locus_tag="VYP30_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1808889.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            6607..7971
                     /locus_tag="VYP30_001964"
     CDS             6607..7971
                     /locus_tag="VYP30_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808890.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGIKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2860 a         1089 c         1394 g         2669 t
ORIGIN      
        1 ttggcgatga tttctttgtg tgaatcccta ttgacgacat ctataatttg gatatttgtg
       61 tctttgatat cgagtagttt tgtgataaaa tgtaattgtc ccatatgaat ctttctaatg
      121 agttgtttga tcgcttttca ttatagatct tatgggactt tttttctaca ataaaatagg
      181 ctccataata tctatagggg atttacccac tacaaatatt atagagccca aaaatgctct
      241 gaaacactga tttcaaagca ttttttgtta gtttaaaatt actcccattc ttcttttcca
      301 aacgtacaat atatccaaaa ccattcaaaa tactagattc tattttttat aatatcacta
      361 aatccaccta attataggac gttttcagat ttttagtccc gtcccagtcc cagtaccgga
      421 gaaatattgt tttaatataa tatctctttt tgtcttctaa gctcttaaaa gcaaaagaac
      481 aagtaaagag tcaagacaag gataaaaagt ccatattagg gcaaataaaa agctttaaga
      541 cagatgacaa atctaagtca aataagaaag accatagcaa aggtgcagag agataaatat
      601 tggcggtctt cggactgcct ttattttttt atccattttt caaatcaaat ttattcagac
      661 tatatatgca catatacact taaattcata taaaaacatg gcttgtaaaa aattacttta
      721 atcacaataa tcgcatttaa aattgtgatg tttgcaagct aaattacgga cttcacttgg
      781 aagttttccc ttgtatcttt tataatagat agaaaatttg ctggcagatg aatatccaac
      841 agattctgct atctctttta taggtagttc agtgtttaaa ataagagttt cagctacatt
      901 cattcttttt ctttgagtgt actctgtaat gctttgacaa tatttttcct taaataaatt
      961 ttttaattta gtaccactca ttttagatat tttttcaagc gtgccttgat ttacattcgt
     1021 tgcaaaatga tcatctaaga atcttgctac atcttcaagt gctttatcat catcaatttc
     1081 aattttatat ttttttctat ttaagtatgt gtcaattact atacttatcc attcatttgc
     1141 ctttgcttta aagaaaaaat cagcggcagg agcgtccatc ttacaattta atatttccat
     1201 tgccactctt tctaaggcct ttgtaagtat tatttgattc ggttgaagca aggttgaata
     1261 aaaagattct ggattaatgt taatagatgc taaatgtttt tctattagct cttttttaaa
     1321 accaatggaa acagcaagat aacaacaatt ctcgtgtaat aaaaaaacaa aatcatcttt
     1381 tatattatca aaatcaaaag tacataaaga gtttgcggta atagtttgat acggattaaa
     1441 cttttctccg tttgcactga caatgtaact tgaataaatt gaaacatagt ctgacatact
     1501 ataagtgcta ttttgaacta cttcctcttt gatataaaaa tcatgtatat cgataatgaa
     1561 gctgcctcct tcataaaacc aatataggcc ttctgcataa gttgaattct cttttttcca
     1621 acaaaatgta tgacctgcac ttgaatactt ctcattgttt ttacattcat ctactttcat
     1681 ataatctttt acaaaatcat aatatgacat aacacactat cccttttaga caatattcca
     1741 attagcctta ttaattcaaa actattgtat tagtaattat aacagatgta taatagaaaa
     1801 gcaatgatag atattatcaa ttaagcgaat ttatatctaa aagggatatt aaagaaagga
     1861 gatatgctta tgaagattta caaaaaacta tttgcttatg tccaagataa gaaatatctt
     1921 ggggttttgg ccataatttt ttctgctata tctgctctac ttacagtata tggatattat
     1981 ttaatctaca aatttctaga taagttaata attaattcaa atttatccgg tgcagagagc
     2041 atagcattaa aatctgttat tacactaaca agtggagcga tattttattt tgtctcagga
     2101 atgttttcac atatcttggg attcaggctt gaaacaaatt taagaaaaag gggaatcgat
     2161 ggtctggaaa aagcaagttt taggttcttt gacttaaatc catctggtca aataagaaag
     2221 attatagatg acaatgctgc acaaactcat caggtggtag cacacatgat tcccgatagt
     2281 tctcaggcaa taatcacacc cgtacttgta cttgcacttg gctttatagt aagtataaga
     2341 gttggcataa ttttgcttgc tcttactata attggtggct taattttagg ggcaatgatg
     2401 ggcgagcaag aatttatgaa gatataccaa gaatccctat ctaaactaag tgctgaaact
     2461 gttgagtacg tgagaggaat gcaagttgta aaaatattta aagcaaatgt agagtctttt
     2521 aaaagctttt ataaggcgat aaaagattac tcaaagtatg cttatgatta ttccctatct
     2581 tgtaaaaggc cttatgtttt gtatcaatgg ttattttttg gactgattgc aattttaatt
     2641 attcctatag tttattttat gactagctta gctagcgcaa aggtgatttt acttgagctt
     2701 atcatgattt tatttttatc aggagttctc tttgtttcat tcatgagaat gatgtggtac
     2761 tccatgtata tttctcaagg aaattatgca gtagatactt tagaggcgct ttacgaagat
     2821 atgcaaaaag acaaattagt gcatggtaat atcaataatt ttaaaaacta taatatagaa
     2881 tttgagaatg ttagctttgc ttataatgat aaagctgtca ttgaaaattt atcctttaat
     2941 ttagaagaag gaaagtccta cgcacttgtc ggttcatctg gatcaggcaa atcaacagta
     3001 gcaaaactta tatcaggttt ttataatgtt aataaaggaa gcataaagat aggcgggata
     3061 gcaataagtg aatattctga cgaagcctta attaaagcca tttcctttgt ttttcaagat
     3121 tcaaaattat tcaagaagag catttatgat aatgtagctt tagctaataa agatgcgacg
     3181 aaagatgacg ttatgagagc cttaaaatta gcaggatgcg atttaatatt agacaaattc
     3241 ccagaaagag aaaatacaat cataggctca aaaggtgttt atttatccgg tggagaaaaa
     3301 caaagaattg caattgctag agcaatttta aaggattcca aaattattat tatggatgaa
     3361 gcatcagcat ctattgaccc agataacgag tttgaattgc aaaaagcttt taaaaatctt
     3421 atgaaggata aaacagttat catgattgca cacaggctat ctacaattaa agaccttgat
     3481 gaaattattg tcatggatag tggaaaaatt atagaaagag ggtctgacaa agaattaatg
     3541 tcaaaagata caaggtataa gagcctgcaa gagatgttta acagtgcgaa tgaatggagg
     3601 gtttcaaatg aaagagtttt ataaaaaaag atttgctctt acagatggag gagcaagaaa
     3661 tttaagtaaa gcaacactgg cttcattttt cgtttattgt ataaacatgc ttcctgccat
     3721 attacttatg atttttgctc aggaagtttt ggaaaatatg ggcaaaagca atggctttta
     3781 tatagtattc tcagttttga ctttgatagc aatgtatatt ttgctttcta tcgaatacga
     3841 taaattatat aacacaacct atcaagaaag tgcagattta agaataagga cagcggagaa
     3901 tttatcaaaa ttacctctat cttacttttc taaacatgac atttccgaca tttcacaaac
     3961 aatcatggct gatattgaag gcatagagca tgcaatgagc cactcaatac caaaggtggg
     4021 cggcatggta ctgtttttcc cattaatatc tgtaatgatg ctagcgggca atgtcaagat
     4081 gggtttagct gtaattattc catctatttt aagctttata tttatacctt tatctaaaaa
     4141 atatcaggtt aatggacaga atagatatta tgatgtctta agaaaaaact cagaaagctt
     4201 tcaagaaaat atcgaaatgc aaatggagat taaagcatat aatttatcga aggatattaa
     4261 agacgactta tataaaaaaa tggaagatag tgagagaata cacttaaagg cggaagtaac
     4321 tacaatttta actttgtcta tatcttcaat atttagcttt atatctcttg ctgttgtgat
     4381 atttgtcggc gtaaatctaa ttattaataa agagataaat tctctctacc ttataggata
     4441 tttactagct gctatgaaga taaaagactc tttagatgca tctaaagagg gcttgatgga
     4501 aatattttat ttatcgccca aaatagaaag attaaaagaa attcaaaatc aagatttaca
     4561 agaaggcgat gactatagct taaaaaaatt tgatattgat ctaaaagatg ttgagtttgc
     4621 ctacaataaa gacgcaaaag ttttaaatgg tgtcagtttt aaagctaagc agggagaggt
     4681 cactgctttg gtaggtgcaa gtggctgcgg taaaacaact atcttgaaac ttatatcaag
     4741 actttatgat tatgacaagg gacaaatctt aatcgatggc aaagatataa aggaaatatc
     4801 aacagaatcc ctttttgata aggtgtctat tgttttccaa gatgtggttc tctttaatca
     4861 aagcgttatg gaaaatatta gaatcggtaa gcaagatgca agtgacgaag aggttaaaag
     4921 agcagcaaaa cttgcaaatt gcacagattt tatagaaaaa atggataaag gtttcgatac
     4981 agttattggt gaaaacggag ctgagctatc aggaggagaa agacaaagat tatcaatagc
     5041 cagagccttc ttaaaagatg cgccgatatt gatcttagat gagataacag caagccttga
     5101 tgttaacaac gagaaaaaga ttcaagagtc tttaaataat ttagttaaag ataaaactgt
     5161 tgtaatcatt tcacatagaa tgaaatccat agaaaatgca gacaagatag tagttcttca
     5221 aaacggaaga gtagaaagcg aaggtaagca tgaagagctt ttacaaaaat caaaaattta
     5281 caaaaattta atagaaaaga caaaaatggc agaagaattt atttattagg aggactacaa
     5341 tggataataa aaaattaaaa gtaaaagatt tagtaagtat cggtgttttt ggcgtaattt
     5401 attttgcctt catgtttgga gttggtatga tgggcttgat tccaatattg ttcttaatat
     5461 acccgacagt attagccata gttgcaggaa ctgttgttat gttatttatg gctaaggttc
     5521 aaaagccatg ggcactattt atatttggta tgatatcacc acttgtgatg tttgcagctg
     5581 gtcataccta cgtagttgtg gttttatcac ttatagtaat gataatagca gaattaatta
     5641 gaaagattgg taattataat tcatttaaat acaatatgct ttcttatgca atcttcagca
     5701 catggatatg tagctcttta atgcaaatgc ttttagcaaa agaaaaatat atggagtggt
     5761 ctttgatgac gatgggaaaa gattatgttg atgtattaga aaagttaata acttatcctt
     5821 acatggcttt agtagcctta ggtgctttct taggaggaat tcttggagca tatataggca
     5881 aggctctatt gaaaaaacac tttgaaaaag caggcatcgt ataatgccta ctttttcttc
     5941 aaatgctccc tttaatccca atccgatctc taagatatta gtcgtattta tcacaggctt
     6001 aactgttatg catagcataa acatccgttt tgagctggca attgtttgtc ttattggtat
     6061 tttgctttat ttgaatggat acaaaaaaac acttttcaaa tggattatat tgtgtgggat
     6121 actttactcc ttgcctaatt ttatggtgtt atctgaatta aaccctatag ttaagatgtt
     6181 tttgagtata cctattgtta ttagaatgtt tattttacca tttatggcag caagctttat
     6241 gataaagacc tcggatgtag gcgcaataat ttcatcgatg gataagctta agatttcaaa
     6301 gaatgtatcc atacctattg cggttatgtt tagattcttc ccatctttta aggaggagaa
     6361 gaaaaacatc aaaatagcta tgagagtaag agggataaat tttaaaaacc cagtcaaata
     6421 tcttgaatat gtttctgtgc cactactcat tatatcatct aatatatcag atgacattgc
     6481 aaaagcggca gaaacaaagg caatagaaaa tccaattgcc aagaccagat acattcgcgt
     6541 aaagatacag ctaattgatt ttgtttatgt tttagcggtt gttggactta ttgtgggagg
     6601 cttaatatgg ttgaaataaa aaatttaagt cttgattatg gtgaagagca tatattagat
     6661 gatatatcac tatccatagc cgagggagag tgcgtgctat ttacaggaaa aagtggaagt
     6721 ggtaagtcat ctttaataaa ttcaatcaat ggactagctg taaggtatga taacgcaaag
     6781 acaaagggcg aaataattat tgatggtaag aatataaaaa atttggaact ttatcaaatc
     6841 tcaatgcttg tttcaactgt ttttcaaaat cctaagacat atttttttaa tgtcaatacg
     6901 acattagaat tattatttta tttggaaaat atcggtcttg caagagaaga gatggacagg
     6961 cgtttgaagg atatgcttga gatattcccg ataaaaaatc ttttgaacag aaatatattt
     7021 aatctatccg gcggtgaaaa acaaattctt tgcattgcag cttcttatat agcaggtaca
     7081 aagattatag ttatggatga gtcttcatcg aatttagata ttaaaagcat aagtgttttg
     7141 gcaaagatgc taaagatatt aaaagagaaa ggcataagca taattgttgc agagcataga
     7201 atttattatt tgatggacat agttgaccgt gtatttttaa tagataaagg aaagcttaaa
     7261 aaaacttata ctagaagtga atttttaaag ctagataaaa atgaattaaa tgctttaagt
     7321 ttaagagata aagaattaag taaattaaaa gttccttatt taaaagaagg tggagagtat
     7381 cagataaaaa atcttagcta caaatttact gatgatgagt gtttaagctt aaaagatatt
     7441 tcattcaagc ttgggaaaat ttatggcata ataggatcca acggacgagg aaaatcaacg
     7501 cttttaagat gtttaatagg tcttgagaaa aaatcaaaag aagaaattta ttttaaggga
     7561 gagaagctat ctaaaaaaga aagactcaaa aactcttcac ttgttatgca agatgtaaat
     7621 catcaattat tcacagatga ggtattcaac gagcttagat taggaataaa gaattttgat
     7681 gaagaaaagg cgaaaatcat tttaaaagat ttaggcctgg acgaatttat tgaaaggcat
     7741 ccgatgagtt tatcaggagg gcaaaagcaa aggcttgcaa tagcatctgt tatgtgcaag
     7801 acttctccat ttatcttttt tgacgaacct tcaagtggta tggattattc caatatgata
     7861 aaaatatctg aactgattaa taagtataaa accatggata aaataatttt tattgtttcc
     7921 catgatatag aatttttaaa tgaagtggca gatgaaattt ttgaattata aaatagagtc
     7981 tgttaaacat gtctatagaa ctggtaaatt gt
//
LOCUS       DAVMBH010000072         7599 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVMBH010000072 DAVMBH010000000
VERSION     DAVMBH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.072"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..540)
                     /locus_tag="VYP30_001965"
     CDS             complement(<1..540)
                     /locus_tag="VYP30_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1808891.1"
                     /translation="MTYSFIALDVETANSFRGSLCSIGLVKFIDGQEVDSFYTLINPE
                     EKFSSRNIKIHAIKPEDVIGAPTFPEVQKEIINFIDNLPIVAHNARFDAYALQDVYLK
                     YEIPFDNIQYFCSYQVCKIILTDLPNHKLHTLAEHFKISLDHHNALSDARACGLILLE
                     ILKLSKQTSIRKMLKNLGYP"
     gene            complement(530..1126)
                     /locus_tag="VYP30_001966"
     CDS             complement(530..1126)
                     /locus_tag="VYP30_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808892.1"
                     /translation="MNRLKELRQEKKLSQKEIAETLGFSLRSFQRMENGESQIKPEKA
                     QLLADYFGVSVANLLGYENNFIESVKNLSQKDGSDEVFFKAFRAYYELKTADGRENLL
                     TLKDEDFLNKYREEILKNLIPNIKELSKQEIEKYLSDEKLLNEAKQKLNDFLFTIGTL
                     NPQETQLLVDFISLSYKDKQIVLNILGSLNQKETHHDL"
     gene            1345..1545
                     /locus_tag="VYP30_001967"
     CDS             1345..1545
                     /locus_tag="VYP30_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1808893.1"
                     /translation="MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKER
                     LAIKSMVAEIKPDITIDEIFYS"
     gene            1730..2158
                     /locus_tag="VYP30_001968"
     CDS             1730..2158
                     /locus_tag="VYP30_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808894.1"
                     /translation="MGKKHQVVKFKDIAEKLPELEGKNLEEIAGVLGYRNLESCRVNL
                     YNLRQNKRLGFEVEKGVYTKFELLDDTVKEELEEKELSERGHFLQSLDYYKVAKNAFE
                     IAEDKTVKAETRQKAERDILDAMKHIPKKHRAILYDMMEG"
     gene            2505..2957
                     /locus_tag="VYP30_001969"
     CDS             2505..2957
                     /locus_tag="VYP30_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808895.1"
                     /translation="MTETTYDIIAKSLDRISMELHQADENNDFLRIGLLSGQLKAIKE
                     NLHRLLWIELPELNESHKIEAVSKSTTGIFFHPGIFEMDAMRQAFFKRQAKHFFDNAT
                     EQQEYIEYAEKEYLEATKTLKDILFNTNNGTRQVNKDCLVEKFEEAMQ"
     gene            2954..3133
                     /locus_tag="VYP30_001970"
     CDS             2954..3133
                     /locus_tag="VYP30_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808896.1"
                     /translation="MTQSEFYNRMTKIKDRHPNLFQFIIDFLDDKVSTEEVYDFLKME
                     RSYQVNHIKNYKARA"
     gene            3135..3350
                     /locus_tag="VYP30_001971"
     CDS             3135..3350
                     /locus_tag="VYP30_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808897.1"
                     /translation="MNELDLSNTQAVFVSVVLIGILLYLNHRDRKKSAQIERENQQTI
                     ETPSDDLNPDYGRYIQLAGVRVSGGME"
     gene            3347..3640
                     /locus_tag="VYP30_001972"
     CDS             3347..3640
                     /locus_tag="VYP30_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808898.1"
                     /translation="MSYTVKIYLDFEKIPDETYFTKEIFLAMCTDNATKLAVTMGLLA
                     KQALDLETRAVILKTLNTIIENQKAILQGVASGQITFLNKSKGEEELDESIRE"
     gene            3621..3962
                     /locus_tag="VYP30_001973"
     CDS             3621..3962
                     /locus_tag="VYP30_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1808899.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGLEISLTTKLTERTVQDIIKR
                     LIIKHNIPIVGVRNGFYRGYFIPRNKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            3955..4227
                     /locus_tag="VYP30_001974"
     CDS             3955..4227
                     /locus_tag="VYP30_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808900.1"
                     /translation="MFSLSRESEKDLTHGILEVVERYLEAHEKVPPRLTKLINRIELK
                     EELKISDNTLNKWESQGLRRYQPPDDGSRMIYYLVTDIWKFLGVDE"
     gene            4224..4739
                     /locus_tag="VYP30_001975"
     CDS             4224..4739
                     /locus_tag="VYP30_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001263812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808901.1"
                     /translation="MRVIELILSADKLPLFGFLKSTPTQVWKNGEHYKFIYFEPIGEG
                     LTAFHYKGLYVAVKDENEEVEGWELTRDLEIGLASPDLLMILKNLEVNKLTEQRQGLG
                     VELKGWVFNLICNGIYTRYETSLFVRLLFVNGYSFSQLVDLFSAIVKRKDLASYFLEV
                     ATKFYKEVAFE"
     gene            4732..6183
                     /locus_tag="VYP30_001976"
     CDS             4732..6183
                     /locus_tag="VYP30_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HEV1808902.1"
                     /translation="MNSNDIVNKIIEENQQEAPPEVVDLTQARKTNEEHNSLNLAKRP
                     RGDGFDRGLDNLRKILSGDSKLKGAIQYNTFTYEIEVTRPMKLNGRTLNGAIDDLIIR
                     EIRAYIATKYKLDYKKPDIADFLEIVAGENSYNPLKDYLESCESEYKELVNQREPFDI
                     LRHYLNIKDDEYNRIIMDLFFRGAVAKVFDPTVKFDFVLDLTGRQGVGKTQFFEGLFT
                     HKYFTTVETFTDKDDKARMVRNWCVFDDEMVASKKASFSELKKFITETKLEFRPPYAS
                     SDRRLPKSFIIVRATNDHDYLNDLTGERRFLVVEVHKDTAYKGRKWTEKDRRAFWGAM
                     VVAWRANQVLNLTDEQEKLVNEVRSRYKFVDEILEDLERYLDTPYPKRMYQFPMTDRM
                     RYYYIYDMMNEGYYRNNRGGTVELDTDTYGELVDRDKMTINLFFQEVYLTDKAPPKDK
                     AKVKKYMQNRDGWEHRRSTRFGKSIKPAYVKKM"
     gene            6722..6886
                     /locus_tag="VYP30_001977"
     CDS             6722..6886
                     /locus_tag="VYP30_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HEV1808903.1"
                     /translation="MNPNKDYTPFLQDNFIIFNKNGIIEMKKIPDFGSVVFTSQDGNI
                     VQIETTIKER"
     gene            7040..>7599
                     /locus_tag="VYP30_001978"
     CDS             7040..>7599
                     /locus_tag="VYP30_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808904.1"
                     /translation="METLQTIETKIDKLIEQNKKAIEMTEAELVKASQAISDAQAKLV
                     QAQEEINSEKYVEAKSDLWTAERTKEFHEGRLKELVTTPIISYDEYHATVKEIYRLAD
                     EQQNTFFTPAVAKLLEIVKLGDESAKEVGKVNEIFRKLEKDISKNNEDYKRDKNGGWF
                     RGPFSSLSYSPRNALHGYQDDLKEIA"
BASE COUNT         2723 a         1193 c         1600 g         2083 t
ORIGIN      
        1 aggatatcct aaatttttaa gcatttttct tatacttgtt tgtttagata atttcaatat
       61 ctctaataat attaaaccac aagcccttgc atctgataaa gcattgtgat gatctagaga
      121 tattttgaag tgttcagcta aggtatgtaa tttatgattt ggtaaatcag ttaggattat
      181 tttacatact tgatagctac aaaaatattg aatgttgtca aaaggaatct catactttaa
      241 ataaacatct tgtaaagcat aagcatcaaa tcttgcatta tgagcaacaa taggtagatt
      301 gtcaatgaag ttaatgattt ctttttgtac ttcagggaaa gtaggggctc caatgacatc
      361 ttcaggtttt atagcatgta tttttatatt tctactacta aatttttctt caggattaat
      421 taaagtataa aaggagtcaa cttcctgtcc atctataaat tttactagtc caattgaaca
      481 tagacttccg cgaaatgagt ttgctgtttc aacatctaaa gctataaaac tataagtcat
      541 ggtgagtttc cttttgattt agtgagccaa gtatatttaa tactatttgc ttatctttgt
      601 aagataggga tatgaaatct actagtaatt gggtttcttg aggatttaat gttccaatgg
      661 taaatagaaa atcattaagt ttttgctttg cttcatttaa aagtttttca tctgataaat
      721 atttttcaat ttcttgttta cttaattctt ttatgtttgg aatgagattt ttcaaaattt
      781 cttcacgata tttatttaga aaatcttcat cttttaaagt caataaattc tctctaccat
      841 cagctgtttt tagttcatag tatgctctaa atgctttaaa aaatacttca tcagagccat
      901 ctttttgact taaatttttt acagattcaa taaaattgtt ttcataaccg agtaagttag
      961 caacgcttac cccgaagtaa tcagcaagta gttgggcttt ttctggttta atttggcttt
     1021 ctccgttttc cattcgttgg aatgacctta aagaaaatcc caaagtttca gctatttctt
     1081 tttgagatag ctttttttct tgtcttaatt ctttcaatct attcatgttt tatcacacct
     1141 ttcacagatg attataacct tatgtttaaa aaaagtcaaa aaatgacgta aaaaaatcaa
     1201 aaaaactatt gacaacgtct aaaactgacg ttataataaa aatcaagctt atgttgcgtc
     1261 ataaaatgac gtcaagcacc ccctccaacc tttcacactt tcaatctatt catggagggg
     1321 gattttttag aaaggagcaa atctatgagc aaactacgag gctatcgggt tatgttagga
     1381 ctaactcagc aacaaatggc ggacaagcta aaaatttctt tgcagtcgta caacaacaaa
     1441 gaattaggta aaacgccatt caatgacaaa gaacgtctag cgattaagtc aatggttgca
     1501 gaaatcaaac cagacataac aatagacgaa atattttata gttagaaagg agcgaactaa
     1561 tcgcaatact actctatatt tacagatttc tcatgtggtg ctttaccact ggggattgac
     1621 aacaaaaaag tcacttgctg aatgtttggc gacagaagca agcgactgga tcaagagtat
     1681 agatattttt tctatacctt gattatagca tagaaagaca aggtaaacaa tgggaaagaa
     1741 acatcaagta gtaaaattta aagatatagc tgaaaaattg cctgaattag aaggtaaaaa
     1801 tttagaagaa atcgctggag tattaggcta ccgcaacttg gagagttgca gggtcaacct
     1861 ttacaatctc agacaaaaca agcgtctagg gtttgaagta gaaaaagggg tttacactaa
     1921 gttcgaactc ttggacgata ctgtaaaaga agaactggaa gaaaaagaat tgtctgaacg
     1981 tggtcatttt ttacagtcgc tagactacta caaagtagca aaaaacgcct ttgaaatagc
     2041 agaagataaa acagtaaaag cagaaacccg acaaaaagca gagcgtgaca tattggacgc
     2101 gatgaagcac attcctaaaa aacatcgcgc tatactttat gacatgatgg agggctagga
     2161 tggaagcaaa aacccacttc gctagattca tgcgtagagg catggagtta gcaaggcaat
     2221 tacatagtaa agaaattcaa cgtgatgaat ttgatagagc ctggaaaaga ttaggcgatt
     2281 aaatcgaaaa cgaaacgaag aaaaactaag aaaaccgaag agcaggcaag caattagaaa
     2341 aggttttgaa atcgagtgct gacacgacga ttctaagcac ttgtttagaa aaaatgtggg
     2401 tgattaccca cgaaacatca ctacaagcgt ccgccaactt ggggcaaatg cccagcgttt
     2461 ggagtggtga aataatccaa tataggaaaa agggaaaaca gactatgaca gaaacaacat
     2521 acgatattat cgctaaaagc ttggatagaa ttagtatgga attacaccaa gcagacgaaa
     2581 acaatgattt tttgagaata ggactcttat caggacaatt aaaagctatc aaagaaaatt
     2641 tacaccgctt actttggatt gagcttcctg aattgaatga aagtcataaa atcgaggcag
     2701 tctctaaaag tactactgga atctttttcc atccaggtat ttttgagatg gatgcaatga
     2761 gacaagcatt ctttaaacgt caagccaagc atttttttga caatgcaaca gagcaacagg
     2821 agtatataga atatgctgaa aaggagtatt tagaggctac taaaaccttg aaggatatcc
     2881 tttttaacac taataatggg actagacaag taaataaaga ttgtcttgta gaaaaatttg
     2941 aagaggcaat gcaatgacac aatcagaatt ttacaaccga atgactaaaa tcaaggatag
     3001 acatccgaac ctctttcagt tcatcattga ctttttagat gataaagtaa gcaccgaaga
     3061 ggtgtatgat tttctgaaga tggagcgaag ctatcaagta aatcatatca agaattacaa
     3121 agcgagagca taacatgaac gaactagatt taagcaacac acaggcggtt tttgttagcg
     3181 tggtactgat tggcatactg ctttatctaa accaccgaga ccgcaaaaaa agcgcccaaa
     3241 ttgagcgaga aaaccaacag acgatagaaa cacctagcga tgatttaaac cctgattatg
     3301 ggcgatatat ccagcttgca ggggtaagag tttccggagg gatggaatga gttacacagt
     3361 gaagatatac cttgattttg aaaaaatacc agatgaaacc tattttacta aagagatttt
     3421 tctagctatg tgtacggaca atgcaacaaa gttagctgta actatggggt tgctggcaaa
     3481 acaagcgttg gatttagaga ctagggctgt tattttaaaa acccttaata caatcataga
     3541 aaatcaaaaa gctattttgc aaggggtagc gagcggacaa ataacctttt tgaataaaag
     3601 taaaggagag gaggaactgg atgagtctat cagagaatga caagcgagtt ttaagactaa
     3661 tcaaggtagg ggctgagaac tccataacag ggttagaaat cagcctgaca accaagctaa
     3721 cagaaagaac cgtgcaagat attattaagc gtttaataat caagcataac atcccaattg
     3781 tgggggttag aaatggattt tatagaggtt atttcatacc tagaaacaaa ggcgagttac
     3841 tagatggtgc taaggctttt tacaaccaag tacaggagga gagcaagcgc ctagcggtgt
     3901 tgatgaatag cgatttagaa agctacaaag aaaccttgaa ggaggtgggc ggatatgttt
     3961 agcctaagcc gagaaagcga gaaagaccta acgcatggca ttctggaggt agtggaaaga
     4021 tacctggaag cgcatgagaa agtaccgcca agattgacca agttaataaa taggattgaa
     4081 ctcaaagagg aattgaaaat tagtgacaac acgctgaata agtgggaaag tcagggttta
     4141 agacgctatc aaccgccgga cgatggttca agaatgattt actatttagt aactgacatc
     4201 tggaagtttc tgggggtgga tgaatgaggg tgatagagtt aattttatcc gctgacaaat
     4261 tgcctttgtt tggctttctc aagtctacgc caacccaagt ttggaagaat ggggaacact
     4321 acaaatttat ctattttgag ccaataggcg agggcttgac ggctttccac tacaaaggtt
     4381 tgtatgtggc agttaaagac gaaaacgagg aagtagaggg ctgggaacta accagagatt
     4441 tagaaatagg tttggctagt cctgacttgc tgatgatcct gaaaaattta gaggtaaata
     4501 aattgacaga gcaacggcag gggcttggag tggagttaaa aggctgggtt tttaacctga
     4561 tttgtaacgg catttatacc agatatgaga cttcgctttt tgtccgcttg ctatttgtca
     4621 atggctacag ttttagtcag ctggtggact tgttttcagc aatcgtcaaa cgcaaagacc
     4681 tagcaagcta ctttctagaa gtagcgacaa aattctataa ggaggtggct tttgaatagc
     4741 aatgacattg taaataaaat cattgaagag aatcagcaag aagcaccgcc tgaagtggtg
     4801 gacttgaccc aagcaaggaa aaccaacgag gaacacaata gcctgaactt ggcaaagaga
     4861 ccaagagggg acggctttga tagaggttta gacaatctga gaaagatttt gagcggagat
     4921 agcaagctaa aaggggcgat acagtacaac acttttacat atgaaattga agtgactaga
     4981 ccaatgaagc taaacggtag aaccctgaac ggtgcaatcg atgacctgat tatcagagag
     5041 attagggctt atattgctac caagtataag ctagactata aaaagcctga tatagctgat
     5101 tttttggaga tagtggctgg agaaaatagc tacaacccct taaaagacta tctggaatct
     5161 tgcgaaagcg agtataaaga gttagtgaat caacgtgagc cctttgatat tttaaggcat
     5221 tatcttaata tcaaggatga cgaatataac cgtattatca tggatttgtt tttccgtgga
     5281 gcggttgcca aggtgtttga ccctaccgtt aagtttgact ttgtgctgga cttgactgga
     5341 aggcagggag taggaaagac acaatttttt gaggggcttt ttactcacaa gtattttaca
     5401 accgttgaga cattcacaga caaagacgac aaggctagaa tggtgagaaa ctggtgtgtc
     5461 tttgatgatg agatggtggc cagtaaaaag gctagttttt cagaattgaa gaaattcatc
     5521 acagaaacca agctagagtt tagaccccct tacgcttcca gtgacaggcg attgcctaag
     5581 agttttatca ttgtcagagc aactaatgac catgattatt tgaacgacct gacaggggaa
     5641 aggcgctttc tagttgtaga agtccacaag gacaccgcct ataagggcag gaaatggaca
     5701 gagaaagacc gcagagcctt ttggggcgct atggtagtag cttggagggc taaccaagtc
     5761 ttgaacctga cggacgagca ggaaaagcta gtaaatgagg ttagaagtcg ttacaagttt
     5821 gtagatgaaa ttcttgagga tttggagcgc tatttagata ctccttaccc aaaaagaatg
     5881 tatcagttcc cgatgaccga cagaatgcgc tactattata tctatgatat gatgaacgag
     5941 ggatactata gaaataacag gggtggaaca gttgaacttg acacagacac ctatggcgaa
     6001 ctggtagata gggacaagat gaccattaac ctattttttc aagaggtgta tttgactgac
     6061 aaagcaccgc caaaggataa ggctaaggtt aaaaagtata tgcaaaaccg agacggctgg
     6121 gaacataggc gatcaacaag atttggtaaa agtattaaac cagcttacgt taaaaaaatg
     6181 tagtcagtgt agtttatttt taaaagtgac tacattttaa acaggaagaa aacccttgat
     6241 acataagggg ttagaaaaaa gtgttgtttt tactatttta ctgactacac ccctaaaccc
     6301 ttggtattat tgacttttat ataaaaatgt agttattttc tatttattaa agagtatatg
     6361 aagataagag ataaaaggcg tttattgttt atttttttgg gagcaaggtg actacatgac
     6421 tacgcatggc gaaaagcctt gtgactgtaa ggcggagagc gtagtcacta gatatcctaa
     6481 aatgactaca ctttttggaa ttgtgaggag gagacctaaa aagaaatgga aatagtaact
     6541 taaatgagta acttttaaga ctgaaatcat atttgtattt tacataatga gaaaatgtaa
     6601 ataggaaatc acaaaaatag ccctcctccc ttgatagaca aggcgagaag ggaggtcgct
     6661 taaatttaac agaatagaag atatgttaaa tatatggcac caaaaaagag aggaaaaaca
     6721 gatgaatcca aacaaagatt acactccatt tctacaggat aactttatta tctttaacaa
     6781 aaatggtata atagagatga agaaaatacc agactttggt agcgtggtat ttactagtca
     6841 agatggcaac attgtccaga ttgaaacaac aattaaagaa agatagctga ctagacaact
     6901 agaggcgtaa cattaaagct aagtagcttt tttgttgcgt ctctttttgt tttgagaaag
     6961 aggaagtaat gaggaataaa gacccagtaa agagttgaaa ccaataagca caatcaaaag
     7021 aaatgaggaa taaaagaaca tggaaacatt acaaactatt gaaactaaaa ttgacaaact
     7081 gattgaacag aataagaaag ctattgagat gactgaggcg gaactggtta aagcaagcca
     7141 agctatttca gacgcccaag ccaagctagt acaggctcaa gaagaaataa actctgaaaa
     7201 atacgtcgag gcaaaaagtg acctatggac ggcagaacgt acaaaggaat ttcatgaggg
     7261 acgtttgaaa gaattagtta caactccaat aatttcatat gatgaatatc acgcaacggt
     7321 taaagagatt tatagattgg ctgatgaaca acaaaatact ttctttactc cagcagtagc
     7381 caaactattg gaaattgtaa agctgggtga tgagtccgcc aaagaagttg gtaaagtaaa
     7441 cgagatattt agaaaacttg aaaaagatat ctctaaaaat aacgaagatt ataaaaggga
     7501 caaaaacggt ggatggtttc gtgggccatt ttcaagttta tcctattctc caagaaacgc
     7561 cttacatggg tatcaagatg atttaaaaga aatagcaga
//
LOCUS       DAVMBH010000073         7461 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVMBH010000073 DAVMBH010000000
VERSION     DAVMBH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.073"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(41..361)
                     /locus_tag="VYP30_001979"
     CDS             complement(41..361)
                     /locus_tag="VYP30_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1808905.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            1119..1490
                     /locus_tag="VYP30_001980"
     CDS             1119..1490
                     /locus_tag="VYP30_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV1808906.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDSQLRIG"
     gene            1498..1710
                     /locus_tag="VYP30_001981"
     CDS             1498..1710
                     /locus_tag="VYP30_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808907.1"
                     /translation="MLVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            2591..3649
                     /locus_tag="VYP30_001982"
     CDS             2591..3649
                     /locus_tag="VYP30_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808908.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            3963..4940
                     /locus_tag="VYP30_001983"
     CDS             3963..4940
                     /locus_tag="VYP30_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808909.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(5487..5645)
                     /locus_tag="VYP30_001984"
     CDS             complement(5487..5645)
                     /locus_tag="VYP30_001984"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808910.1"
                     /translation="MAQIVVIASPIDIQAANPLIADSANPATLFATRTPTYLAAAPAI
                     ALVTRRKP"
     gene            5899..6801
                     /locus_tag="VYP30_001985"
     CDS             5899..6801
                     /locus_tag="VYP30_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808911.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            6857..7210
                     /locus_tag="VYP30_001986"
     CDS             6857..7210
                     /locus_tag="VYP30_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1808912.1"
                     /translation="MELVLPNNYVVIDEEEMMYFDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            7207..>7461
                     /locus_tag="VYP30_001987"
     CDS             7207..>7461
                     /locus_tag="VYP30_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808913.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLT"
BASE COUNT         2446 a          959 c         1363 g         2693 t
ORIGIN      
        1 aaaataatat gtaaagagtc gaggaaatcc ctcggctttt ttatctttcc ttcgcttggt
       61 aatagatctc tacttctttt ttgagatgag acagcataga agtttcctcg gtcagctcta
      121 ggagtgagaa ccctttttgg ataagtttcg catcatccct acaaatccca atgcggacat
      181 agcagatagc cagcctatcg tagcttttct tattcttggc gtcctccagt aaagtgtagc
      241 agatttgctt acacatgttt ttatcttgat tgtatagata gagtgtggaa aggttgagca
      301 ggattgctat tcgcaagtca tataaatgtt gatagttttt atagacttct aagcgttgca
      361 agattttctc ggattattga caaataaacg gacattctga tagacgattg ccctagcggc
      421 ttagtgtaaa ctttacaaat ttggcttgta atttttttat aaaattcact ttagttactt
      481 gacagttatt atattttcgc tcataatata gataaaagga tgggatagga gtttaaaaat
      541 ttgaaagcgc tatccataat cataacgcat aattttctcc ttttcgtgaa aaaagttaac
      601 gtaattttga aatgagctta ataagaggta ctatgtaggt agaaaataaa gataggagaa
      661 aaagtatgaa taaaaaaata ttttgtattc tagtatgtat tatatcattg attagtctag
      721 ctatagtctt tccatggggc tggtcgatat aatgtaaggg agcttgagtt gttagtggag
      781 gataaaatgt taagagtaat agtagttatt caatctttag taataatact gcttgctgtt
      841 gctttattat tatctcggaa aaactttgat tcgttaaatg ttgttcttat aatgatgatc
      901 gtatcacaat tgttgttatt agtatatttg ataaaatcag ggaatcagtg attagctgtt
      961 atttgaatta agtaaactgt taagcttcaa gcagtaactg gttttaaata tttaaaataa
     1021 gataaaggaa ggaagtctaa tttaggtaac taaacaaagc ctgcgatcac ttgttaggaa
     1081 accatcctaa ccatgcttaa taaaaaagga gaaaataaat ggaactcgta ttaccaaata
     1141 attatgttgt gattgatgaa gaagagatga tgtaccttga tgggggggct atatatatac
     1201 ccaggtgggc aattacagga gccattactg gtgcagcata tgcagcatta gcagcagcag
     1261 gaggtggagg ccttcaacta gttcttgcat cttatggatt acgctccgca ctggtagctg
     1321 ggattgttaa aggtttagga gtattaggaa ttcatattgg aaatgctttt gcaaatactg
     1381 ttattagaag tattgcatct gctggaattg gtgctggagc tgattggatt tttaccaata
     1441 ttattgatgg ctgggatggg cgacgtgata gtcaattgag aataggttaa taatcttatg
     1501 ttggttgttt taatttcagt tattgttgca ttcctgtatc ataaaattac agagtatgtc
     1561 aacaacagga aaattgatat tgttattttt ctatcattgc tgatttctca ttttatttgg
     1621 aattactatt ttttaccaat tgaaatattg atagcaatca gtggagcaaa tttactatta
     1681 agttttttaa aaaaattaca gactaaataa tattaatctg tgtaatacag tagctcggtc
     1741 attagattct attgaagata taaattaaaa atgaggctgg gaaaaaactc aatttgaaaa
     1801 tgaaattgag taaatttttc tattatataa cgcatattat caagattttt gaacacctga
     1861 taatatgcac ttttcttatt ttaaagattt tttgcctttc ttcatttctt ggatgaattg
     1921 gagagatgac ttgatttagg tgtttgacat tactatagat aggatttagc agtactaata
     1981 tgaactcata ttataggtgt agacttaaat tttggaagca agctaaagga tatcttatct
     2041 aggtaactaa gtgctataac aagatatatt ggtggagtta gtatggcaac tattactaat
     2101 gctcttaata ttgcggctac tgttgctgaa gtcttctcat taggaggagc cattgcatat
     2161 ggtttagata tcgtagacgg taaatttgat gggtatttat gggcgtaaaa ctatagctat
     2221 gaaacatttt tttgcaggaa ttggtgaaat tcattttttg ttatttttat tatatctaag
     2281 catgtctgct agtccaatta ttggactagt gattggatat actaaaataa atctaataaa
     2341 ttctattatt atagctcttg gtatgatatt ggcattaatt ttggtattat caagagtgta
     2401 tagaaaatat ttttatagag acgatgatga ctaaagtttt tatcaataat ttgggctcct
     2461 tgtcaactgt agtgggttga agaaaagcta acgtctgggg aaggggttaa agctttgctt
     2521 tatcaaatat tgacttacag agttgctcta ttgtattgat gtattcttag taaataatat
     2581 ggtgttttga atgaaagatg atcagaaata tttattagcg ggactttatt cgcttctagt
     2641 tgcaatattt tattttccat tgattgagtc caaggggatt tttgtaagta tattgatggc
     2701 ggttttactt ttatatttaa tatacttcat tgcaacagtc attcatattg tgataattaa
     2761 gtttataaga aaaaaatctt ttaagtattt ggttctatat ccatttactt atgatgggag
     2821 ctggagattt caacctataa acttactcta ctttccagaa atggtgagag atgtcattcc
     2881 gattaattta gttcaagaat attgccaagg acaaccttac ggactgttaa aaaagatgct
     2941 gaaaagaatt cgattgtcac gagagatatc tttactcctg gctaccatta tcgtctattt
     3001 ttttacgcat agaattctac ctctttcagt atttacgttc atattttctt acatattgct
     3061 atttgcacaa tcttatttgg gtggtaatac cgcttggatt ggaaatagaa gattaataat
     3121 agatgatgaa tttgaaaaaa tcttgctttc aaaaagttat ataaaagaaa tatcatctgc
     3181 acgatactca gaatacttga catgtgaata caaaaacttt acaccaatca tattgttagc
     3241 tatttttgaa aatttgcttg actcctactt gcttcagaat cagagtgagg ttgacttaga
     3301 tattttttat aaagttttac ctttgcttta taaagaaaaa tatactatgg gattcaatta
     3361 ctttgtaagt ttaaattatt tactatataa ggttggattt ttgggaatca tttacgataa
     3421 tgaagcatta agagatttgt caaaacaata tttaaacaaa aatatttcgg aattacaaga
     3481 tggttctttc gaggacggta tacaagatgc tgttgcctct aaacaaatag tagttataaa
     3541 tgaatttata gcttgtttaa attccagatg cgtgccatcc caatatgata gattttttta
     3601 taaagataga ccttatattt tttccagaaa gagtcctatt aaggggtgaa aatttgttac
     3661 atttggatta acaagtgtcc tagggattag aaataactct agtatagcta gatatttttg
     3721 agtaactaga aatatcatta gtctacccat atgattgcca gaaaagatgg ctgatgaatc
     3781 ttatttatac tgttgcagta ggcgttgtct aggataaata agctatcttg atgggggaga
     3841 ttggaataat tttagtagaa acattaaagg attatggaca agtagcgcag gattaggtga
     3901 tgcaatgtgc taagttggct tggtgttagc agtagtatta tttaacaatg gaaagtagac
     3961 taatgaaaaa taagcgttat ttttttgaca caattttaat aattttactg cttataagca
     4021 cgatattttg tgtcagccca gtatttataa aattggacat cttaggaact ccctctcatg
     4081 ccatcttaac ctttgtattg gcgataccgt tattctatat tttgtctcaa tgcttacata
     4141 ctttgctatt actagtttcc tcaatctttt gtaaattaag accaatttat ttttatttta
     4201 tatttgtgat cattatagga gctaggaaat actatcgaat tctctttcac caactaatgg
     4261 gatttagtcc aggaatagca gtgttttata aggagagtca aacaactaag aatctgttta
     4321 aattttacta cttcttgtac tttacaacac taatttcata ctattttttc tttacttttg
     4381 tgtatgacaa atcgttgctt ttgcctctta ttccattttc tattatcata gcattagtac
     4441 aaaaacttta tagaattgag aatcaacaat tatttctgtt aaaatcaaaa gtactaacaa
     4501 tactggaatc taagagggat tgtgagttta atcttcagga ttatcatgaa atttggaaat
     4561 tgcaatcaaa atctgagttg ccatgcgtgg ctttatctta tatcagtttg atcaagccat
     4621 atctttcaga gagtgtgcgt gaacaaattg atttattaga agttaagcga tttaaaaaaa
     4681 taaatcatcc aatatcactt tatggtatgt tggatgttat aaaattaaat ctatatttac
     4741 ggcattataa tgaaaaaaat aaatatgaat caatgttaaa gaaaatttta gaggtaagac
     4801 cagactttgt tttaatcgag cagaatattg atgatagttt aaatagctcg caacccttat
     4861 ctttatcttt agccatttca gaaatccaac ttttgcttga agtgtatatg gggatcaaac
     4921 atgtttcaat taggagataa aaccagaata atatttgcca ttataggggc aagttgcata
     4981 ttagtcagta tgtatcttat tccacttatt aaaactgaga ataaattttg ggaaatactt
     5041 ttatttatat taggtgtatt gctaattgga attgcgttac taagtcaaaa aaaataaatt
     5101 ttgaaatagt attagtgagt tcgcaatcat ttattgctag tggtttagaa ctgttaagtt
     5161 tcaaacaata attgatttta aaccttaggt aacctataaa aacaaataag gtagagaaag
     5221 gatatcttat ataggtagct aagtgataaa aacacagtcg tctatcactt gttaggaaac
     5281 tatcctaact atgcttaata aaaaaggaga aaataaatgg aactcgtatt accaaataat
     5341 tatgttgctc ttgagcaaga agagatgatg tatcttgatg ggggattttc tattctgaga
     5401 tgacctgttg caacagccat taatatagct tttaatggtg ttttaggtgg aggagcaatc
     5461 agtctagtta gaaattatat tcgtaattat ggtttgcggc gagttacaag cgcaattgct
     5521 ggagcagctg caagatatgt tggggtacga gttgcaaata gagtggcagg atttgcactg
     5581 tctgctatta atggatttgc agcttggatg tcaattggcg atgctattac aacaatctgg
     5641 gccaacaatg atgtaaatag gagagaccca aatttaaacg ccttgtggta actagatatg
     5701 ggtattaaaa tggaaaaaat ttttgttatt attttttttg tatgtttatt tatatcatcc
     5761 ataacttttt tagcctatga ttttgttagc gaagaaataa aaaagttgat tatttggatg
     5821 aatgtcgttt ttttgatttt aatcatagca atgataattt atccaaaatc aagaaaatga
     5881 taaggacact gtaaaattat gatacgtaaa ctaatcattt ttttattaat gctccctctt
     5941 tttgtcttgt ggctagagtt gcatgtccta gtgaataact tgcaattgaa tctagaaatt
     6001 ccctttgatt ttgtggttag tacgagtctt actttttttg ttttgatatt atcaaaaata
     6061 gttttagaca tactatacgc attgaaagat ttgtacaaga aagaagctct tattacgatt
     6121 tttcccttta tttttataag aaggaaaaaa gtgaatgtga gattctcgcc ctatttttca
     6181 ttccatcgta aaagtttgtc gcctgatgat ttaagatcta ggattatatg gagttttatt
     6241 cttgaaattg ctattatcct agtatttatt ttaaaaattc cttttgcaat catcatgctt
     6301 actacaatat ttttctggac tataatggat atcaatcatc tcgtttttaa taagacggaa
     6361 tttcttttta atcaaaacaa atggcaaaaa gaagattcgt ttgaaagtga tttgacgaaa
     6421 acgttaaagg ataagataca aaaatcagag ctaagttatt ctgacttaat gtctcttcag
     6481 ctgtatgatg cgatgaacca atccaccttt ttaacggata gtgaactttt tgaggatatt
     6541 ttgaaaaaaa tcgaagattc tcataacacc cttctgtgta caggtcttgt cgagttactg
     6601 ctgtatgaaa tttctattag taacaataac aactggcaag aaaaggttga taaaattaga
     6661 atacagctca tcagaatcaa tcaattagat tttttctatt atacaagttg gttaaggcaa
     6721 aattttgatt tctgtatgaa tagagagtat cataaaatga aatctcggaa attattactg
     6781 agtaataaaa agatagttta agttcgtcct atttgtaaaa caaatgaaac aatttcaact
     6841 aaggaggaga aaataaatgg aacttgtatt accaaataat tatgttgtga ttgatgaaga
     6901 agaaatgatg tattttgatg ggggagctta tttaagcaag cgtgcttgtc aaggaatttg
     6961 cgcagcttta gctatgagtt caggaacttt tatagcatta gctggagctg cagttttaac
     7021 caaaaaacta ataaactata ttaaggttgg aggtcttgga ggctggctta ttggtgcagc
     7081 agcaggtgta ttggctacag cagcagggaa aatagcttac tatattggat atggtgttct
     7141 taatagaggt tgtgatatta acgggaaccc ttatccttgg gatggattca tatctgcaac
     7201 agtaagatga gtaatgtaga taagattcga aaaatacaca tcatcgtgtg ttgggtgtat
     7261 atatttttat cattcagggc gattataaat gatacggagt attttttgct tattttttta
     7321 gcttttatct actcaatagt atcactacct ctatattctg tgaaaaataa aatagtatct
     7381 atctgtctag ccataaattc gattctgtta atgagtttcc ccattttaat caataagttt
     7441 ttcccagaaa gttttttgac t
//
LOCUS       DAVMBH010000074         6219 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVMBH010000074 DAVMBH010000000
VERSION     DAVMBH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.074"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(114..389)
                     /locus_tag="VYP30_001988"
     CDS             complement(114..389)
                     /locus_tag="VYP30_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1808914.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(495..1334)
                     /locus_tag="VYP30_001989"
     CDS             complement(495..1334)
                     /locus_tag="VYP30_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1808915.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1476..2324
                     /locus_tag="VYP30_001990"
     CDS             1476..2324
                     /locus_tag="VYP30_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1808916.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2417..3334)
                     /locus_tag="VYP30_001991"
     CDS             complement(2417..3334)
                     /locus_tag="VYP30_001991"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1808917.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3772..3977
                     /locus_tag="VYP30_001992"
                     /pseudo
     CDS             3772..3977
                     /locus_tag="VYP30_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4288..4581)
                     /gene="rpmA"
                     /locus_tag="VYP30_001993"
     CDS             complement(4288..4581)
                     /gene="rpmA"
                     /locus_tag="VYP30_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1808918.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4598..4942)
                     /locus_tag="VYP30_001994"
     CDS             complement(4598..4942)
                     /locus_tag="VYP30_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1808919.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4958..5272)
                     /gene="rplU"
                     /locus_tag="VYP30_001995"
     CDS             complement(4958..5272)
                     /gene="rplU"
                     /locus_tag="VYP30_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1808920.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5308..5395)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5454..6158)
                     /locus_tag="VYP30_001996"
     CDS             complement(5454..6158)
                     /locus_tag="VYP30_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1808921.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
BASE COUNT         1911 a         1276 c         1038 g         1994 t
ORIGIN      
        1 acaatatttt cggaacattc aactttttaa ctctatttat tactagattt cataattaaa
       61 aaacctactg accaagctag aaagcttgat acaataggct ttttaaagac tgattattta
      121 acagcgtctt taagagcttt accagctttg aatgctggta ctttagaagc tgcaattgtc
      181 atttctttac cagtttgtgg gttgcgacct ttacgttctg cgcgctcacg aacttcaaag
      241 ttaccaaaac cgatcaattg aactttttca ccagctgcaa gatagtcagc tactgctgca
      301 aatacagctt caactgctgc tgctgagtct ttcttagtca attctgtagc ttctgctact
      361 ttagcgatca aatcttgttt gtttgccatg ttaatgattc ctccaaataa tttctaatta
      421 acaaatataa tcatatccta aaatcccttt taggtcaagt taaaaacgct atttcttccc
      481 attttattta ttttttagga gtggtaacgt atcaaaatag cccaagcgtt ctcacccgtg
      541 tgagtttgaa taatggaacc cgtttccaaa acagaaattg gcttttcaac ataagcttgt
      601 aagctttctt tcatctcttt tgcccaatca tcactaccag aatatgaaat tccaatctct
      661 gctacagcac gttcagaaag cgatgttatc aactcatcta accatttttt aaatgtttta
      721 gttccacgac ctttaaccat tggctgcaat tcatggtctt tcatttgcat gacagcacgg
      781 atattgagaa gagagctcaa caagccagtt acacggctaa ttcgtccacc tttgacaaga
      841 ttttccaaag ttgaaacacc aatataaagc tctgtatggt ttttaacctc ttctacatga
      901 gataaaattg cctccatatc tttaccttct tgagctaact tcgcagcctc aacaacttgg
      961 aatttcaggg cttggtcagt gaaggaacta tcaacaacag tcacatctgc agtagatagg
     1021 ctagcacctt ggcgtgctgc ttctaccgta cccgaaagag catgggacat atgaatagca
     1081 agaatctggc caccatcttt gcataggtct tcaaaaatct cagcaaagac acctacaggt
     1141 ggctgacttg ttttcggaag attcttactt tcttgcatca actgaagaaa tttaccttct
     1201 tctttcaaat ccgcatcaga ataaacaaca ttatcaatca ttacagataa tggaacaatt
     1261 gtaatatcta attgctttac tagttcaggt tcaatagtaa cagatgaatc ggttacaatc
     1321 ttaatttttg tcatagtatc aatctttcta ttttaggatt cagattggtt tccttacttc
     1381 taattatatc aaaaaaaaga ttaaaaatcc taatggagtc aatcaaattt tccgtaaaat
     1441 ttgatataat caacttataa gaaaagaggt gtcctatgat taaaaaaatt taccctattt
     1501 ttaccatttt actaggtgct gctatttatg cttttggact gacttatttt gtagttcccc
     1561 atcatctctt tgaaggaggg gcgacaggca ttaccctcat caccttttat ctttttaaaa
     1621 tccctgtttc cctcatgaac ctgctgatta atattcccct tttcatccta gcttggaaga
     1681 tttttggagc caaatccctc tattctagtt tactaggaac cttagctttg tccggctggt
     1741 tagctttttt tgagcatatt ccccttcata ttgatcttca aggtgattta ctaatcacag
     1801 cccttatagc gggaatccta ttgggaattg gccttggaat tatttttaat gctggaggta
     1861 caactggcgg aactgatatt ctagctcgta ttctcaacaa atacactcat atatccatag
     1921 gaaaactgct ctttatctta gatttttgta ttctcatgtt gattctccta atcttcaagg
     1981 atttgagatt ggtttcctac acgcttttgt ttgattttat tgtttctcgt gttattgatt
     2041 tgattggtga aggaggatat gccggcaaag gctttatgat tatcacaaaa cgtcctgacc
     2101 aacttgctaa ggcgattaat gatgacctcg gaagaggtgt tacttttatt tctggtcaag
     2161 gctactatag taaagaaaat ttgaaaatca tctactgtat tgtcggaaga aatgaaattg
     2221 tgaaaacgaa ggaaatgatt catcgaatcg atcctcaagc ctttataact attacagaag
     2281 cccatgaaat cctaggagaa ggcttcacct ttgaaaaaga ataaaaagag gtaatgtcgt
     2341 gacctcaaaa gttagactaa atcatctatc ttttgggtta cagacaacct cttttttatt
     2401 ttatttactc aagctcttaa gaccaattcc gagttacttc ttcatcagcc tttaactgat
     2461 ccactaattg gtcaactgag tcaaatttgg tcatatctcg aatgcgatca agccaataaa
     2521 ccatgacggt ttccccataa atatcttgat taaaatcaaa aatattgact tcaaaacgtg
     2581 cttcttctcc atcaaaggtc acatttttcc cgacactagc catagcacga tacttctgtc
     2641 tttgaatctc aacatcaaca acataaacgc catctgctgg catataagta cggtctaaaa
     2701 gcactaaatt cgctgtcgga taaccaattg tacgaccacg agcattacca tgaaccacca
     2761 tacctcttga tggaagcggt gcccccaaaa gttttcctgc ttctttcaca tttccatcta
     2821 aaatagcttg acggatacga gttgaactaa tctttccttt ctcatcttct acaggtggaa
     2881 caatgataac ttctccatca aagtaatcct ttaaatcttc tgctgttttt ttgtcagaac
     2941 caaatgtata atcaaaacct gcaacaataa ttttggcatt catagccttg atataagttg
     3001 caaagaattc ttgtgcagtg agactagcga attgactact aaaatcaagg agatataatt
     3061 cttctacacc ttcgcgcttt aattttcttt cacgttcagc agggttcaaa atatgcaaaa
     3121 acaaatctgg atgataaggc tctaaagcga tctttggaga ttcattaaag gtcataacga
     3181 cgataggcaa caaatccttt ctcgcagcct tgttggcaac acgaaataat tcttgatgcc
     3241 ccttatgtat gccatcaaaa tagccgagaa caacgactga atcagatggt gtgccaatat
     3301 ctttttggtt ttttatagga atagtaataa tcataaaata attatatcat agcgatagct
     3361 atttctggaa cagaaaatct gaaatgttgt ttttttcaca tgaagtgtac ctgttttcaa
     3421 aaagcacttt attctatcgt tgcttaacta tgaactttgc aatattcttc tcaaaaactt
     3481 gtaggacatc ttcaaaattt tgcaaggagt gattagactt gttcggtaac cataaagtgt
     3541 catactatgc ttatgtatga aaaagcaatg caactaactc ctgagaactt taaattacta
     3601 attggtgccg aaaaggtaga atttagaatc gaggtacacc tatggctgta aaatttacaa
     3661 aatgagacaa cttgggcaag atgtttgaag aatttcctaa actccctgat ttgaagcaag
     3721 tcactttccc taatgacaaa gaaaaaagcc aaaacagcaa agaaaaacta gatgactgct
     3781 ttccaacaac tcccatctag tgtgcttcag actgggctat ttttctctcc atctgttagc
     3841 ttggattctc agaccgtttc agctaaagaa tatcttttcc cttatcagaa ggaacggctc
     3901 aagccattca gacaagtgaa gggacgacaa gccaatattt gaaaccagat agcagttctt
     3961 atagtcaatt gaaataaaat ctgaagaaat cgagtaggaa actcatatca atgtttaaca
     4021 gtgttctatt ccagattcat actcaatgaa aattaaagtg caaactagga agttagccgc
     4081 aggctgtact tgagtacggc aaggtgaaat tgacatggtt tgaatttgat tttcgaagag
     4141 tatcaatcca ctatacatat taaaaagtat gggtaccaaa acaaaaaaac aggctctccg
     4201 aaaactcgga aagccttatt ttaagctgtt tctagcttcc tcacctttac atttcaaggt
     4261 tcgggataaa aggttcaatg gaccttttta tttagcgatt gggtaaacag aaacttgttt
     4321 tttatcgcgt cctttacgtt caaagcgtac tacgccttca actttagcga acaaagtatc
     4381 gtctccacca cgaccaacgt ttacacctgg atagatgtgt gtaccacgtt gacggtaaag
     4441 gattgatcca cctgttacag tttgtccgtc agctgcttta gctccaagac gttttgcttg
     4501 tgaatcacgt ccgtttgatg tagaacctcc accttttttg tgggcgaaaa gttgcaagtt
     4561 gttaagagtc atttttaaca taatgttttc ctccgtgtta gttttctgtg ataactctgg
     4621 tttggacgaa ctcagaatag ttctccgata agtttgccat acctaagaaa aatgattcaa
     4681 agaataactg ggtcatttct ctctggtgtg aaggaagatc ttttggtatt tcaaccatca
     4741 gatagccacc ttcatcttcg tttaattcta ggattggttc atagcctgca aatttctcaa
     4801 tagaattgat aaagttaatg gcaagcgtag aaaccgatgc acacacgaca tctaagccgt
     4861 attcgccact ctcggcgtgt ccagtaattt ccgcactcct cagctcgcca tcttcggctc
     4921 tctcaaagac tgcctgtatc atgtgttctc cttaaaatta agcgttgatt gcgttgatga
     4981 caacttttgt atatggttga cggtgacctt gtttacggtg gctacctttt ttaggtttgt
     5041 acttgtaagt aaccactttc ttttgttttc cttgtttttc aacagttcca actacagtag
     5101 ctccagcaac aagtggagtt ccgacaacag tgttttcacc accaacaaga acaacttcgt
     5161 taaaagtaac ttcttgacca gcttcaacgt tcaatttttc aacgtaaact gcttgaccaa
     5221 cttcaacttt aacttgtttt ccgccagttt tgataattgc gtatgtgctc attatgcacc
     5281 tcctatgatt tttatgggtt tccccgattt tttgtgaaga ctcgcctagc atcgtgggac
     5341 gaaccactta aacttgaata atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca
     5401 tagtcaactc ttcaagtata gcatatctcc tattttctta caagtaataa cacctaaaat
     5461 gaagcttttt cttttacttt tttctgccaa gaggcaaaaa gcatgctgag gtaaaaaacg
     5521 ctcatcataa taggaacacc aagaatggtc ttttcatgat agaaaatcgt caaataggct
     5581 gaaaagacaa cgccaaggac aaaactacta agcaggctaa caaatatgaa tccttcacgc
     5641 aaaaaaggag tgtgcttggt tcggaaataa tctccaaaag ccagcatggt ccgtttgata
     5701 ttccctgtca taaaagcgtt attataggca atacccgata cttctccaaa agcagttgtc
     5761 accagtccca tacagaaggc caagggcggc actagataga tattatccac agtttgcggc
     5821 acaaaagcaa taatgattga taagattgcc aagggaatca aggacagaat aggttttttc
     5881 acaattctca atttttcctt ataaatcgtt aataaaaaga ctcccatcat aaacgctagc
     5941 aaggtgagaa ccttgtccct aacatccgaa acattatttt taattaattc tactgaaaga
     6001 aagacaacat ttccagtttg tccagctaca agggtattcc cgcgaacaat aaaagtgtaa
     6061 gcatccacat atccagcaca aaacgtcaaa aaaagtgcta accttttaga ctgacgtgat
     6121 atttttctta taggtaataa cctcatttta cctcccattg tattttctct tagaaatatt
     6181 gtaccatttt ctttctaaaa aatcgtaggc taccattta
//
LOCUS       DAVMBH010000075         6117 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVMBH010000075 DAVMBH010000000
VERSION     DAVMBH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.075"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            177..1946
                     /locus_tag="VYP30_001997"
     CDS             177..1946
                     /locus_tag="VYP30_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1808922.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVVQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHINVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            1970..3925
                     /locus_tag="VYP30_001998"
     CDS             1970..3925
                     /locus_tag="VYP30_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1808923.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKILFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            3927..4364
                     /locus_tag="VYP30_001999"
     CDS             3927..4364
                     /locus_tag="VYP30_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1808924.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            4426..5562
                     /locus_tag="VYP30_002000"
     CDS             4426..5562
                     /locus_tag="VYP30_002000"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1808925.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQRTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT         1877 a         1031 c         1250 g         1959 t
ORIGIN      
        1 gtctaacttt tggggtgtag ttcatgtaca cctgatatga tgcgttttat aatttttaag
       61 cctttttgcc cagcctcgtc aaaagtaatg ttttgacaca aaatctgtga caaaacttta
      121 gttttaaagg tttttaactt tgtatatact agttttaaga aaaggaggat gatctaatgg
      181 aagaaaaagt atcattgaaa gtcagggttc aaaaactagg gacatcgctt tcaaatatgg
      241 ttatgcccaa tattggagca tttattgctt ggggagtatt gactgccctc tttatcgctg
      301 atggctatct gccaaatgaa cagttagcta ctgttgttgg tcctatgtta acgtatttat
      361 tgccaatcct gattggttac acaggtggat atatgatcca tggccaacgt ggtgccgttg
      421 taggagctat tgctactgtt ggtgcaatca caggttctag tgttcctatg tttatcggag
      481 ctatggtaat gggcccactg ggaggatgga ctatcaagaa atttgatgag aagttccaag
      541 aaaaaattcg tcccggattt gaaatgttag ttaataactt ctcagctggt ctcgttggtt
      601 ttgcattatt gcttttggct ttctacgcaa tcggtccagt cgtatcgact cttactggag
      661 ctgttgggaa tggtgttgag gctattgtca atgctcgcct ccttcctatg gctaatatta
      721 tcatcgaacc ggctaaagtc cttttcctca ataatgccct caatcatggc atttttactc
      781 ctctgggagt agaacaggta gttcaagctg gtaagtcaat tctcttccta ttggaagcta
      841 atcctggacc aggcctggga attctattag cttatgctgt attcggtaaa ggttctgcta
      901 aatcttcttc ttggggggca atggttattc atttcttcgg agggattcat gaaatttact
      961 ttccttatgt tatgatgaag cctactctat ttttagctgc tatggcggga ggtatctctg
     1021 gaacttttac ttttcaactc ttagacgctg gtcttaaatc tccagcttca ccaggttcta
     1081 ttattgcgat tatggctacg gcgccaaaag gtgtttggcc ccatataaat gttcttctag
     1141 gtgttttagt agcagcagtt gtttctttcc ttgtagcagc ccttattctt catgcagaca
     1201 agtcaactga ggattcgctc gaagctgctc aggcggctac ccaagcagct aaggctcagt
     1261 ctaaaggtca gttagtatca acttctgttg atgcagttgt ttcgacagac tcagtggaaa
     1321 aaatcatttt cgcctgcgat gctggtatgg gaagctctgc tatgggagct agtattcttc
     1381 gagataaggt taaaaaagca ggtctagaga ttccagtatc taatcaggca atctcaaatt
     1441 tgcttgatac accaaaaaca ttaattgtta ctcaggaaga actgacacca agagctaaag
     1501 acaagagtcc aagtgctatt catgtttctg ttgataattt cttagcgtcc cctcgttatg
     1561 atgaaattgt agcttcatta acaggagctt ctccaatagc agaaattgaa ggagatatac
     1621 caacttcagc accagtagat agtcaggaaa ttgaccttaa ccatattgat gctgtagtag
     1681 ttgcttatgg taaagcacag ggaactgcaa ctatgggctg tgaaacgatt cgggctatct
     1741 ttagaaacaa gaatattcgt attccagttt ctactgccaa aatttcagaa ttaggtgaat
     1801 ttaattctaa aaacataatg attgtaacaa ctatttcttt acaggcagaa gtgcagcaag
     1861 cagcaccgaa ttctcaattt cttattgtgg atagtttagt aacaacacca gaatatgaca
     1921 aaatggctgc tagaatgtac aaatagaact agaggtttct aaattacgaa tgctattaac
     1981 caaacgagaa gaacaattat tgaaggcttt cctacatgta gggaagcttt caatgcaaga
     2041 tatgactgaa atcttacagg tttcatctag aacaatttat cgaactttat cagatttgac
     2101 agatagcatg gagcaatatg gaatcgaaat aacgaagcat gggaaatact atattttgac
     2161 tggagagttg gatgatttgc cgacagaact tgaagtgtta gttgagtata gtccccaaga
     2221 aagacaagag ttgattacct atcgccttct gactgagagc ggttttgtca ccaatgaagc
     2281 attgcaagag tgcacgaaag tcagtaatgt aactattatt caggatattt cagatattga
     2341 taagcgtctt ttagactttg atctgaaaat tgaacgacaa aaaggttatc ggatttctgg
     2401 tgattcagtt ggtaagagaa gatttttggc tattttactg acaaactgta tctcagtagc
     2461 agatttttca accggtaatt ttgggagctt tgatatttta gaagcagata gaactaggct
     2521 ggccagtcag attgttaata agcaactgtc aggttttcca gatatggatg ctaggatgaa
     2581 gatgtttttt gcgatcttgt tatctcttat aggtcaggag caaaacattg aaaattcacc
     2641 taatactagt aagcaggctt tggaaatttc tcaaaaaatt tttcaaactt actctaagca
     2701 gactgcacaa ttttatagta ttcaggaaat tatctatttt gcgagcatct tggatgaatt
     2761 aatcattaaa cgtcaggaca atccgctctt tacggagaaa tttgatggtg aatttttcta
     2821 caatatttca aatctgattg atacggtttc catgtatacc aagattgact tttttaagga
     2881 caagatttta ttcaattttc ttttccatca tattcggctc agtttaggcg tccctatcct
     2941 ttttcagggt gaaaatttgc cagaatctgt ccagatttta gttgaaagga ataaatttct
     3001 ttatacagtc atcagtcttt tagtgaatga tatttttccg aaatatcttc atacagagta
     3061 tgagtatggc atgattgccc tacattttat ctctagctta ggccgtagtc cagagattta
     3121 tccagtccgt gttttgcttt taacggatga acgtcgggtc actagagatt tattagtcag
     3181 taaaattaag agtgttgctc cttttgtaga gttgatagat attcagtctc tagtagatta
     3241 ccacagtatt gatctcagtc agtatgatta tattttatct accaagccgc tgactaatca
     3301 ggaaatcgat gtaatttcta gttttccaac cgtcaaagaa ttgcttgaat tacaggaacg
     3361 acttcagtat gtacaggcac atcgtacaat tgtcgcgcgt gatgctatcg ctccagagaa
     3421 aagttatgac ttgcaagatt atttaatatc tagtagtcag cttttgagtc aatttgagtt
     3481 ggttcaattg gagaataatc aatcatttga gcacacggta gaacaaatca tccaatatca
     3541 gaagaatgtg agtgacagag attacctaac aagaaaattg ttatctcact tccagaatag
     3601 tcctatggct attcctaata ctggtctggt gcttttacat agtcagtcta gcaaagtaac
     3661 aacaaatagt tttactatgt ttgaactcaa actacctatc tccgcattgt caatgaaacg
     3721 agaggaagaa gaggtcaaaa ggtgtctgct aatgctaatg tctaaagaag ctagcgagga
     3781 agctagagat ttaatgacag ctattagtca gtcgattatt gaaaatcatc tttatacaga
     3841 gatttacaag acgggaaatc aatccattat ttatcagatg ctaaatacta tttttaacga
     3901 aaaaattaag aaattggaga actaatatga aacttgaaaa acatttgatt aagcttaata
     3961 aacaattttc taacaaggag gaagctattt gttattgtgg gcaagttctt tatgagggtg
     4021 gatatgttaa tgaagactat attgaagcca tgattgagcg agataaagag ctatctgttt
     4081 acatgggtaa ctttatcgcc ataccgcatg gaacagatgc agcaaaaaag gatgtcctca
     4141 agtctggtat tacagtcgtt caagtcccta gaggggttga ttttgggaat gtatctaacc
     4201 ctcaagtggc aacggttctt tttggcattg ctggtattgg taatgaacac ttagaaatta
     4261 ttcagaaaat ttctatcttc tgtgcagatg tggataatgt tcttaaacta gcagatgctc
     4321 agtcaaaaga ggaagtattg cgcttatttg atgctgttga ataattgaat ttcgtcattt
     4381 gtcatctagt atatatgtcc ctcaaatagg aaaaggagaa attgaatgaa acattctgtt
     4441 cattttggtg ccggtaatat cggtcgtggt tttataggtg aaattctatt taaaaatggt
     4501 ttccatattg attttgtgga tgtcaataat cagataattc atgctctaaa tgaaaagggc
     4561 aagtatgaaa ttgaaattgc acagaaagga cagtctcgta tagaagtaac taatgtggct
     4621 ggaattaata gcaaagaaca tcctgagcaa gtcattgaag cgattcaaag gacggatatt
     4681 attactactg caatcggacc taatatactc ccttttatcg ccgaacttct agccaaagga
     4741 atcgaagctc gccgagttgc aggaaataca caggcattgg atgttatggc ctgtgaaaat
     4801 atgattggcg ggtctcaatt tctttatcaa gaagtcaaga aatatttaag tccggaaggt
     4861 ttgacatttg ctgataacta cataggtttt ccaaatgctg cagtagacag gattgttcca
     4921 gcacaaagtc acgaagattc cctttttgtt gtggtcgagc cctttaatga atgggtcgtg
     4981 gaaaccaagc gtcttaaaaa tccagattta cgtctagaag atgtgcatta tgaagaagat
     5041 ttagaaccct ttattgagcg aaaacttttt tcagtcaatt ctggacatgc aacttcagct
     5101 tacattggtg cgcattatgg tgccaagaca attttggaag ctcttcaaaa tcctaatatc
     5161 aaatctcgga ttgaatctgt attagctgaa attcggagtc tcttgattgc caaatggaac
     5221 tttgataaaa aagaattgga gaattatcac aaagtcatta tagaacgatt tgaaaaccct
     5281 ttcatagtgg acgaggttag tcgcgtagct cgtactccaa tccgaaaatt aggctataat
     5341 gaacgattca tccggccgat acgtgaattg aaagaactca gtttgtcata taaaaaccta
     5401 cttaaaacag ttggctatgc ctttgactat cgcgatgtaa atgatgaaga aagtattcga
     5461 ttaggtgaat tgttggctaa acaatcagtc aaagatgttg ttatacaagt tacaggttta
     5521 gatgaccaag aattgattga gcaaattgta gagtatattt aatctttttc gaaagtctct
     5581 tcaaatcagg ttagcatcca tctgcaacct caaaacagta ttttgagctg acttcgtcag
     5641 ttctatctac aacctcaaag cagtgctttg agctgactcc gtcagtctta tctgcaacct
     5701 caaaacactg tttgagttat ctgcggtaat ctttctagct tgtctttgat ttttgttgtt
     5761 atttataagg taaaagaagc tggacaaaaa gtcttcaaaa tcggaaaaag gcagcctatc
     5821 gggtgttcaa aaatcttgat aggatgtcct ttattatgga aagccttatt ggattttctc
     5881 ctcagattga gtttttgatc agctttatga gataggtctt gctagagatg tagcccatca
     5941 tgttattttt atggacagtg ggaaaattgt tgaaaaaaat aatgcccatc aattctttag
     6001 tcgtccaaga gaagaacgaa ccaagcaatt ttggaacgaa ttctttcgaa tgcgatctat
     6061 atagtaaaat gaaacaagaa caggacaaat cgatcaggac agtcaaatcg atttcta
//
LOCUS       DAVMBH010000076         5869 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVMBH010000076 DAVMBH010000000
VERSION     DAVMBH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.076"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            105..584
                     /locus_tag="VYP30_002001"
     CDS             105..584
                     /locus_tag="VYP30_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1808926.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VYP30_002002"
     tRNA            678..749
                     /locus_tag="VYP30_002002"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1002..2547
                     /locus_tag="VYP30_002003"
     rRNA            1002..2547
                     /locus_tag="VYP30_002003"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2599..2671
                     /locus_tag="VYP30_002004"
     tRNA            2599..2671
                     /locus_tag="VYP30_002004"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2632..2634,aa:Ala,seq:tgc)
     gene            2796..5697
                     /locus_tag="VYP30_002005"
     rRNA            2796..5697
                     /locus_tag="VYP30_002005"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5774..>5869
                     /gene="rrf"
                     /locus_tag="VYP30_002006"
     rRNA            5774..>5869
                     /gene="rrf"
                     /locus_tag="VYP30_002006"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1726 a         1140 c         1674 g         1329 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc gtcaggacca cttgatgaaa
      781 aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg acaagcgaaa gcagttgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaac
      961 aataaatctg tcagtgacag aaatgagtga gaactcaaac ttttaatgag agtttgatcc
     1021 tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtagaacgc tgaaggagga
     1081 gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc tgcctggtag
     1141 cgggggataa ctattggaaa cgatagctaa taccgcataa gagtagatgt tgcatgacat
     1201 ttgcttaaaa ggtgcacttg catcactacc agatggacct gcgttgtatt agctagttgg
     1261 tggggtaacg gctcaccaag gcgacgatac atagccgacc tgagagggtg atcggccaca
     1321 ctgggactga gacacggccc agactcctac gggaggcagc agtagggaat cttcggcaat
     1381 ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga tcgtaaagct
     1441 ctgttgtaag agaagaacga gtgtgagagt ggaaagttca cactgtgacg gtatcttacc
     1501 agaaagggac ggctaactac gtgccagcag ccgcggtaat acgtaggtcc cgagcgttgt
     1561 ccggatttat tgggcgtaaa gcgagcgcag gcggttagat aagtctgaag ttaaaggctg
     1621 tggcttaacc atagtaggct ttggaaactg tttaacttga gtgcaagagg ggagagtgga
     1681 attccatgtg tagcggtgaa atgcgtagat atatggagga acaccggtgg cgaaagcggc
     1741 tctctggctt gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac
     1801 cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta gaccctttcc ggggtttagt
     1861 gccgtagcta acgcattaag cactccgcct ggggagtacg accgcaaggt tgaaactcaa
     1921 aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga
     1981 agaaccttac caggtcttga catccctctg accgctctag agatagagtt ttccttcggg
     2041 acagaggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag
     2101 tcccgcaacg agcgcaaccc ctattgttag ttgccatcat ttagttgggc actctagcga
     2161 gactgccggt aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg
     2221 acctgggcta cacacgtgct acaatggctg gtacaacgag tcgcaagccg gtgacggcaa
     2281 gctaatctct taaagccagt ctcagttcgg attgtaggct gcaactcgcc tacatgaagt
     2341 cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac
     2401 acaccgcccg tcacaccacg agagtttgta acacccgaag tcggtgaggt aaccgtaagg
     2461 agccagccgc ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg tagccgtatc
     2521 ggaaggtgcg gctggatcac ctcctttcta aggataagga actgcgcatt ggtcttgttt
     2581 agtcttgaga ggtcttgtgg ggccttagct cagctgggag agcgcctgct ttgcacgcag
     2641 gaggtcagcg gttcgatccc gctaggctcc attggtgaga gatcaccaag taatgcacat
     2701 tgaaaattga atatctatat caaatagtaa caagaaaata aaccgaaaac gctgtagtat
     2761 taataagagt ttatgactga aaggtcagaa aataaggtta agttaataag ggcgcacggt
     2821 ggatgccttg gcactaggag ccgacgaagg acgtgacaaa cgacgatatg ccttgggtag
     2881 ctgtaagtaa gcgatgatcc agggatttcc gaatggggga acccaacagg tagtacctgt
     2941 tacccacatc tgttaaggat gtgaggagga agacgcagtg aactgaaaca tctaagtagc
     3001 tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg gcaggagggc
     3061 aaaccgaaga gtttactctt cggggttgta ggactgcaat gtggactcaa agattataga
     3121 agaatgattt gggaagatca gccaaagaga gtaatagcct cgtatttaaa atagtctttg
     3181 tacttagcag tatcctgagt acggcgggac acgtgaaatc ccgtcggaat ctgggaggac
     3241 catctcccaa ccctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
     3301 gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
     3361 tcgagcccgt taatgggtga gagcgtgcct tttgtagaat gaaccggcga gttacgttat
     3421 gatgcgaggt taagttgaag agacggagcc gtagggaaac cgagtctgaa tagggcgcct
     3481 tagtatcatg acgtagaccc gaaaccatgt gacctaccca tgagcaggtt gaaggtgcgg
     3541 taagacgcac tggaggaccg aaccagggca cgttgaaaag tgcttggatg acttgtgggt
     3601 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
     3661 tagcgtcgac attagagatt cttggaggta gagcactgtt tgggtgaggg gtccatcccg
     3721 gattaccaat ctcagataaa ctccgaatgc caatgaatta tggtcggcag tcagactgcg
     3781 agtgctaaga tccgtagtcg aaagggaaac agcccagacc accagctaag gtcccaaaat
     3841 aattgttaag tggaaaagga tgtggggttg cacagacaac taggatgtta gcttagaagc
     3901 agctattcat tcaaagagtg cgtaatagct cactagtcga gtgaccctgc gccgaaaatg
     3961 taccggggct aaaacaattt accgaagctg tggatacctt tataggtatg gtaggagagc
     4021 gttctatgtg tgatgaaggt ataccgtgag gagtgctgga acgcatagaa gtgagaatgc
     4081 cggtatgagt agcgaaagac aggtgagaat cctgtccacc gtaagactaa ggtttccagg
     4141 ggaaggctcg tccgccctgg gttagtcggg acctaaggag agaccgaaag gtgtatccga
     4201 tggacaacag gttgatattc ctgtactaga gtatgtagtg atggagggac gcagtaggct
     4261 aactaaagca gacgattgga agagtctgtc taagcagtga ggtgtgaatt gagtcaaatg
     4321 cttaattcta taacattgag ctgtgatggg gagcgaagtt tagtagcgaa gttagtgacg
     4381 tcacactgcc aagaaaagct tctagcgttt aaacatactc tacccgtacc gcaaaccgac
     4441 acaggtagtc gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa ggaactcggc
     4501 aaaatgaccc cgtaacttcg ggagaagggg tgctgactta aagtcagccg cagtgaatag
     4561 gcccaagcaa ctgtttatca aaaacacagc tctctgctaa atcgtaagat gatgtatagg
     4621 gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag cgaaggtatg
     4681 aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag cgaaattcct
     4741 tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt ctcaacgaga
     4801 gactcggtga aattttagta cctgtgaaga tgcaggttac ccgcgacagg acggaaagac
     4861 cccatggagc tttactgcag tttgatattg agtgtctgta ccacatgtac aggataggta
     4921 ggagtctaag agatcgggac gccagtttcg aaggagacgc tgttgggata ctacccttgt
     4981 gttatggcca ctctaaccca gataggtgat ccctatcgga gacagtgtct gacgggcagt
     5041 ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc cctcagaatg
     5101 gttggaaatc attcgcagag tgtaaaggta taagggagct tgactgcgag agctacaact
     5161 cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag ggccatcgct
     5221 caacggataa aagctaccct ggggataaca ggcttatctc ccccaagagt tcacatcgac
     5281 ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt cggtcccaag
     5341 ggttgggctg ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt cgtgagacag
     5401 ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg atctgctcct agtacgagag
     5461 gaccagagtg gacttaccgc tggtgtacca gttgtcttgc caaaggcatc gctgggtagc
     5521 tatgtaggga agggataaac gctgaaagca tctaagtgtg aaacccacct caagatgaga
     5581 tttcccatga ttatatatca gtaagagccc tgagagatga tcaggtagat aggttagaag
     5641 tggaagtgtg gcgacacatg tagcggacta atactaatag ctcgaggact tatccaaagt
     5701 aactgagaat atgaaagcga acggttttct taagttgaat agatattcaa ttttgagtag
     5761 gtattactca gagttaagtg acgatagcct aggagataca cctgtaccca tgccgaacac
     5821 agaagttaag ccctagaacg ccggaagtag ttgggggttg ccccctgtg
//
LOCUS       DAVMBH010000077         5850 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVMBH010000077 DAVMBH010000000
VERSION     DAVMBH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5850
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.077"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(128..1138)
                     /gene="ccpA"
                     /locus_tag="VYP30_002007"
     CDS             complement(128..1138)
                     /gene="ccpA"
                     /locus_tag="VYP30_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1808927.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(1563..2162)
                     /locus_tag="VYP30_002008"
     CDS             complement(1563..2162)
                     /locus_tag="VYP30_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1808928.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(2164..3261)
                     /locus_tag="VYP30_002009"
     CDS             complement(2164..3261)
                     /locus_tag="VYP30_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1808929.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(3261..3998)
                     /locus_tag="VYP30_002010"
     CDS             complement(3261..3998)
                     /locus_tag="VYP30_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808930.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLHHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(4000..4884)
                     /locus_tag="VYP30_002011"
     CDS             complement(4000..4884)
                     /locus_tag="VYP30_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808931.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(4871..5065)
                     /locus_tag="VYP30_002012"
     CDS             complement(4871..5065)
                     /locus_tag="VYP30_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808932.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDCG"
     gene            complement(5062..5268)
                     /locus_tag="VYP30_002013"
     CDS             complement(5062..5268)
                     /locus_tag="VYP30_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808933.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1865 a         1292 c          959 g         1734 t
ORIGIN      
        1 caacctcaaa acagtgtgtt gcgcagcctt taaccagccg cctagtccgc tctatggtat
       61 tcattaagtc aacatctctt gtttaagagc acaaaatcag gaaatcttct cgattccctg
      121 attttttcta tttacgtttt cgtgttgagc tacgttctgt caaaccatga ggtaagagaa
      181 cttcacgttc ttccaactct tccttatgca taatcttggt caacatacgc atactaatgg
      241 caccaaggtc ataaagaggt tgggcaatcg ttgtcaagtt tggacgggta aagcgtgaga
      301 tttgtgaatc atcactagta ataatttcaa aatcttctgg cacagaaaca cccttatcag
      361 ccaaaccgtt caagactcct gctgccaact catcacctgt cacaactgct gcagttgcat
      421 ttgatgaaat caaacgctct gctaaggcgt aaccatcatc atagctatat ttagattcaa
      481 ataccaaacc ctcactataa gcgattcctg cttttttcaa ggtttccttg tagccaacta
      541 aacgaacctt accattgatg tcatccacta gcggaccgct aacgaaagca atacgctcat
      601 tttctttagc aaggtaactc actgcatcaa ttgttgcttg cttatagtca atattgacac
      661 ttggcaactg gtgctcaaca tcgacagttc ctgcgagaac aatcggagta cgtgaacgcg
      721 aaaattctga gcgaatttta tctgtcaagt gataacccat atagataatg ccatctacct
      781 gctttgaaaa gagggtattg acaacagaaa cttctttctc gttatcttca tcgctattag
      841 ctaggacaat attgtacttg tacatttctg caatatcatc aatcccctta gccaaactcg
      901 aaaaataacc attggtaata tttggaatca cgacaccgac agtggttgtc tttttacttg
      961 caagaccacg cgcaactgca tttggacgat aatccaaacg atcaattacc tctagcactt
     1021 ttttacgggt attctctttt acatttttat tgccattgac cacacggctg accgtcgcca
     1081 tggaaacacc tgcttcacga gcgacatcat aaatggttac tgtatcatct gcattcattc
     1141 cttttcctgt cctttctatc tcacacattc ttttacaagt agaggtactg attgaagctc
     1201 tatatctact tacaaaagtg aagatgtgaa aatttcgttt tcatatttct acttattcca
     1261 ttctatcact aattgtaaac actttcaagt gttttttgaa gattgattga aaaaatttca
     1321 tagaaaacct aggtttagct ccttgctacc accttagact aaacacaaag gaggaaacta
     1381 agccctccta aagttatagt aaaatgaaat aagaacagga taaatcgatc aggacagtca
     1441 aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc aatctactat
     1501 aggtattgtt ccattcacta ccgtcaattt tagcacatag ccttcataaa aatattatat
     1561 catcataacc aaccagattc ttttgcgata ttagctgcct ctgttcgatt accagcatcc
     1621 agttttgaaa gaatattggt gacatagttt cgaatagttc cgtttgagag gtaaagctga
     1681 tctgcgattt cttggttgga taagccccgg gcgattccct ttaagacagc aatctcttgt
     1741 tctgtcaacg gattgggacg ggtcatcacc acttccatca attcaggcga atactccttg
     1801 cgtccttcga ggacggtgtg caaggtttgc atgaggtctg caatgcttcg ttcctttaat
     1861 acataagcat ccactccagc cttgaccgca cgttcaaaat acccagcacg cttgaaggtc
     1921 gtcaccacaa ccacctttgt ttcaagcctt tctgatcgta tccactccaa gacttcaaga
     1981 cctgtcttaa caggcatttc tacgtcaagg atggcgatat ctacagactc cttttctaat
     2041 agttggattg cttcttgccc attcttggct tgaaggacag actccacatc tggttgaagc
     2101 gtgagcaatt gacacatggc atctcgcaac atactttgat cttctgcgac taatactttc
     2161 atcttagttt ctctccttat aaggtagtcg aacttgcact tccgttggat gtttctgact
     2221 gattacactt acttctcctg aaaatggaaa aacacgatct cggactgtat ggagctcatc
     2281 tccttttaga aaagcaaagc cgcagccatc atcacttact gttaaaatga gttccttctc
     2341 tgtccgttct aattttaagt aagctttaga cgctttggca tgtttgatga tattggtcac
     2401 caactcaagc aaaatcatag aagccattga ctccaattct tgagtaaggc tagcagtatc
     2461 tagttggtta tccgtttcca cctcaattcc agcaatttct aacatctttt tcacagtctc
     2521 tagttcggat gtcaaagttc tagacttaag attttccaca atggttcgaa cttcacgcat
     2581 tgattctttg ctaatttgct gtatttctct taattccttt tccacttgtg gataagcctg
     2641 catttgaaat agctgcaagg ctagatctgt cttgacacta agcatagcaa aggtatgtcc
     2701 cagactatca tgcaaatcct gaccgatacg attgcgctca ttttctgcta gcaatagatt
     2761 tatctgggta ttttgcttga cctgagcttc tttcaaatcc tcgacaaggc gaattcgaac
     2821 cgagcccaaa gtcatcaaat cgacaaaagt aagaattaca agcatataga ctagaaactc
     2881 aacttcgatt ctctgaaaaa tcaaaagtcg ccccacaaca aggacttgag caaggagaaa
     2941 tgtccataca tgtaaagact ttaaactacg tacgccaaaa tgataaatta agagattgga
     3001 aaggaaaaag aaaaaccaga tataattccc agcaacaaag gcggtattcc cagctacata
     3061 gaccagcatg agcccccaga aaagccaaga taggcgctgg ttcttagtta ttaaaacacc
     3121 caaatacgtc actacaaata gaatatcaac caataaatgc caagcaggaa gctccccaat
     3181 cactacaggt aggatgggaa aaagcataaa aatcaaactg gtccaaaaca tatagtgtat
     3241 gcttttcagt ctttcaagca ttaagcattc tccttatgac cttgaaggta aatagtcaaa
     3301 ccaaataaaa ctgctgaaaa aacaagtaaa taaactgtgg ctgatagatt gatgccaccc
     3361 tcgtttaaga aggtcttgag caactccatc aattgatagg tcgggagaca cttaccaact
     3421 gcttgcatcc agtctggaaa taaagaaatg ggcatccaga gtccgcctaa aacagccaat
     3481 cctagataaa gaagattgcc cacaacagac atcagctgac tagttggtaa gagagtcaag
     3541 gtcaagccaa gtgctacaaa agcaatactc cccacaatca gcaaaatcgc agctccaacc
     3601 cattttacta gaggcatgtc tacacctctt acaaaatgtc caactgtaaa aacaaccaga
     3661 attgagacca aataatcaac cagcatactt gttatctttg atagataata ttctaccata
     3721 tttacagggc tatgatgcaa tgttttctgc cagttgttca tcttatcggt atgtaaaaca
     3781 gctggaaatg agaggatagt tgtcgacatc atggaaaagg cagtcatgga gatgaggtaa
     3841 tcacgcataa aattcgcggg ttcacctggt gtgtcctgat agataccaga aaaaaataaa
     3901 tagaaagccg tcggcatccc taccgacaat agataataga ttaattgtcg tttggtcaat
     3961 aaaaattcta tcttactaag tgctatccat cgtttcatct tagttatctc ccttctgagt
     4021 ctcttcaaag attgtattca acaaactacg attattaact tcgatttctt gcatcctaca
     4081 tcctgcttgg gctaatagtt cccagaaagc atctgcttct cgagtgacta cttgtaaaga
     4141 atcttgcttt agggtccagt tttcaaccaa atttgactgc tctacgactt ccttgtaagc
     4201 tataggaagg ataaagtgct tttctatttc ctcgctacgc atagctagag gcgtcgtatc
     4261 tcgaatcaac tctcccttat ttaagagcaa aatgcggtct gcagtgtgtt ccacttcctc
     4321 aatataatgg gacgaataga gaatggtgac tccttgcgct tttaactcct ggacaatttc
     4381 ccaaaaacgt tgacgagttg aggtatccat ggacgcagta ggctcatcta aaaaaacaat
     4441 ctttggtcgc ccaattaagg tcaagacgaa agaaaagaga cgcttttgac cgcctgataa
     4501 tttttctgcc aactgttctt tttgttgctt gacaaactgc aatagttgat caatttcctg
     4561 attgctcaaa ggatttggat agatacgttg aaagaaagca atcaactctt taacttttaa
     4621 tttctgaacg attacatttt cttgagggag gtaagcccta gtatagtcta acttagaact
     4681 cgtcactggt aaaccttgaa tagatacttg accacttgtg accagtttat ctccaagcaa
     4741 acaatctaag agtgttgtct ttccggcacc atttggacca attaaggcaa cacattcacc
     4801 atcgttgatt tcaaaggaga tgttccgcaa aatttccttg tcttttattt tcttactcaa
     4861 tttttcaact ttaaccacag tcatgagact ctcctttcaa ccactccatt cccataggga
     4921 aaacgacgaa aatcataaat ccaaacccca aagcaccatg aatgaattgg cgaagcaagg
     4981 cttgatcaaa ccaatcagta aacatttcca ctaaccatac caagagtgac aggccgataa
     5041 agaaatagat gatccctctc ttcattcttc aaactccttt ttcacatctc tgactaattt
     5101 caaaccttct ctaacaagcc aagacatgat tccaaagcca gcaaagacct tccaaggaaa
     5161 atggtagaaa tcctcatcca atcccgaaaa catgagatag gtcataactc ctgctactac
     5221 taaactcatt gcaataatca ttttatttct catctcttct tcccccattt catactacaa
     5281 ttatagtctt ttaaaatcag aggaggtaga agcttctgtc actagaaaat atgacaaatg
     5341 tcataaaaaa ttctgttcaa aacaagcaag atacactata caataaaaca caatcagaaa
     5401 aatctaaggc aacttcctca aaagagatat caaactcaat tcacaccaca atgtaaacta
     5461 atacttattt aaaatcaaaa agagtagaaa tttttatcag acaaatacat atatagtgta
     5521 ttgaatctat aacagtaggc cttaaatact aaaatatttc tataaattaa tttaactttc
     5581 ctgatagagc tgttcatatc ttatttcaat tctctatatt atacgttgaa caaaaccctt
     5641 ctattgcttt cttaaaaatt tataagagtt ataaaatctg ttaaatttca atgtgtatac
     5701 ctaaactacg gtatttattg aaaagactgg agacaaaaag tatacgctgc caaaatgaat
     5761 tactgaaaat caaaaaagag agaaccaaac tgattccctc ttaatgtata taatatctag
     5821 ttttaaaaat acacactcac atatctctgt
//
LOCUS       DAVMBH010000078         5566 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVMBH010000078 DAVMBH010000000
VERSION     DAVMBH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5566
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.078"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1258..2517
                     /locus_tag="VYP30_002014"
     CDS             1258..2517
                     /locus_tag="VYP30_002014"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1808934.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAKGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2533..3084
                     /locus_tag="VYP30_002015"
     CDS             2533..3084
                     /locus_tag="VYP30_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808935.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            3077..4354
                     /locus_tag="VYP30_002016"
     CDS             3077..4354
                     /locus_tag="VYP30_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1808936.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQIHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4370..5230
                     /locus_tag="VYP30_002017"
     CDS             4370..5230
                     /locus_tag="VYP30_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1808937.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
BASE COUNT         1681 a          901 c         1253 g         1731 t
ORIGIN      
        1 ttagcgatga tttctttgtg tgaatcccta ttgacgacat ctataatttg gatatttgtg
       61 tctttgatat cgagtagttt tgtgataaaa tgtaattgtc ccacatgaat ctttctaatg
      121 agttgtttga tcgcttttca ttatagatct tatgggactt tttttctaca ataaaatagg
      181 ctccataata tctatagtgg atttacccac tacaaatatt atagagccaa aaatcccgtg
      241 cctcatcaga cacgggattt tgtggtacga caggcatgta tagcaaactg aatctggaat
      301 agcacagcat atcttctaaa atattgttat aaattgattt gaatttcaaa attaaattgt
      361 ttgattctta tttcaatttg ttatagtata tctgatgtca aagttctcgg cgagtcaaat
      421 agcgattccc aagcctgact atcgtgaggt agcggattaa aatggtctgg ggatagaccg
      481 ttttaagtct gacgctggaa ataagaattg tcagaagaag ggatagcgaa atcgtggctc
      541 tacgaacagg aacgtgataa taaggcgtat atagcggata agagggcatc aaactctaaa
      601 gtccaaaaag gtagtcgtaa cctatatgcg taaatcacga gagtaattga attcgtacta
      661 agattttcta ttttcactgt aaccttttaa cgcccttata tcttgtatac acgaggaaag
      721 atgtacgact tatcccgtga ggtctatcac tataaagaga aaacgacaga tagaagtgat
      781 cctgagtcac ggttatctgt ctgataggac ggtatgtata aaacgcttct gtgaactgag
      841 agaaggggga gaagttcttg ctaaaattta gttgaacagc cgtattccga tacttagata
      901 agagatctag tcttagctcc tactcagttt taggggataa aaaaggggca atagcgattc
      961 gagaaagatt atactcttcg aaaatctctt caaatcacgt caatatcgcc ttgtcgtatg
     1021 tgtaggatac tgactacgtc agttccatct acaacctcaa aacagtgttt tgagcaacct
     1081 gcggctagtt tcctagtttg atctttgatt ttcattgagt attagtaatt cagttactaa
     1141 ctcgtcaact ctgatttatc caataaaatt gaaaaggatg gaaaaaagga taaatttatg
     1201 atatacttta ttttgaagac cttattagaa atcttgaaag agtattgaaa acttagaatg
     1261 agaaaaattg ttatcaatgg tggattacca ctgcaaggtg aaatcactat tagtggtgct
     1321 aaaaatagtg tcgttgcctt aattccagct attatcttgg ctgatgatgt ggtgactttg
     1381 gattgcgttc cagatatttc ggatgtagcc agtcttgtcg aaatcatgga attgatggga
     1441 gctactgtta agcgttatga cgatgtattg gagattgacc caagaggtgt tcaaaatatt
     1501 ccaatgcctt atggtaaaat taacagtctt cgtgcatctt actattttta tgggagcctc
     1561 ttaggccgtt ttggtgaagc gacagttggt ctaccgggag gatgtgatct tggtcctcgt
     1621 ccgattgact tacaccttaa ggcgtttgaa gctatgggtg ccactgctag ctacgaggga
     1681 gataacatga agttatctgc taaagataca ggacttcatg gtgcaagtat ttacatggat
     1741 acggttagtg tgggagcaac gattaatacg atgattgctg cggttaaagc aaatggtcgt
     1801 actattattg aaaatgcagc ccgtgaacct gagattattg atgtagctac tctcttgaat
     1861 aatatgggtg cccatatccg tggggcagga actaatatca tcattattga tggtgttgaa
     1921 agattacatg ggacacgtca tcaggtgatt ccagaccgca ttgaagctgg aacatatata
     1981 tctttagctg ctgcagttgg taaaggaatt cgtataaata atgttcttta cgaacacctg
     2041 gaagggttta ttgctaagtt ggaagaaatg ggagtgagaa tgactgtatc tgaagacagc
     2101 atttttgtcg aggaacagtc taatttgaaa gcaatcaata ttaagacagc tccttaccca
     2161 ggctttgcaa ctgatttgca acaaccgctt acccctcttt tactaagagc gaatggtcgt
     2221 ggtacaattg tcgatacgat ttacgaaaaa cgtgtaaatc atgtttttga actagcaaag
     2281 atggatgcgg atatttcgac aacaaatggt catattttgt acacgggtgg acgtgattta
     2341 cgtggggcca gtgttaaagc gaccgactta agagctgggg ctgcactagt cattgctggg
     2401 cttatggcta aaggtaaaac tgaaattacc aatatcgagt ttatcttacg tggttattct
     2461 gatattatcg aaaaattacg taatttagga gcggatatta gacttgttga ggattaaacc
     2521 gtagaggtgt ttatgaatat ttggaccaaa ttagcaatgt tttctttttt tgaaacggat
     2581 cgcttgtatt tgcgtccttt cttttttagt gatagtcagg acttccgcga gatagcttca
     2641 aatccagaaa atcttcaatt tattttccca acgcaggcaa gtctggaaga aagtcaatat
     2701 gcactggcca attactttat gaagtcccct ttgggagtgt gggcaatttg tgaccagaaa
     2761 aatcaacaaa tgattggttc tattaaattt gagaagttag atgaaatcaa aaaagaagct
     2821 gagcttggct attttttgag aaaagatgct tggtcgcaag gatttatgac agaggttgtt
     2881 agaaaaattt gtcagctttc ttttgaggaa tttggcttaa aacaattatt tatcattacc
     2941 caccttgaaa ataaagctag ccaaagagtt gctcttaagt ctggatttag tttgttccgt
     3001 cagtttaagg gaagtgatcg ttacacaaga aaaatgcggg attatcttga atttcggtat
     3061 gtaaaaggag agttcaatga gtaagcatca ggaaattcta agctatttgg aggaattacc
     3121 agtaggtaaa agggtcagtg ttcgtagcat ttcgaatcat ctaggagtta gtgatggaac
     3181 agcctatcgg gctattaaag aagctgaaaa ccgtggaatt gtggagaccc gtcctagaag
     3241 tggaacaatt cgtgttaaat cccagaaagt tgctatagag agattaacgt ttgctgaaat
     3301 tgcagaagtg acttcttctg aggttctggc tgggcaagaa ggtttagaga gagaatttag
     3361 taagttttca attggtgcca tgactgaaca aaatatcttg tcttaccttc atgatggggg
     3421 gctcttgatt gtcggagacc gaacccgtat tcagttgcta gccttggaaa atgaaaatgc
     3481 agttctggtt acagggggat ttcagattca tgatgatgtg cttaaactgg ccaatcaaaa
     3541 agggattcct gttctaagaa gtaagcatga tacctttacc gtcgcgacca tgatcaataa
     3601 agccttgtca aatgtccaaa tcaagactga tattctgaca gttgagaaac tttatcgccc
     3661 tagtcatgag tatggttttc tgagagagac agatacagtt aaagattatt tggacttggt
     3721 tcgtaagaat cgtagcagcc gtttccctgt tatcaatcaa catcaggtcg ttgttggtgt
     3781 tgtaaccatg agagacgctg gtgataaatc accaagcacg acaattgata aggttatgtc
     3841 tcgtagtcta tttttggttg gattatcgac aaatattgcc aatgtgagtc aacggatgat
     3901 cgcagaagac tttgaaatgg taccagttgt tcgaagcaat caaactttgc ttggcgttgt
     3961 gacgcgacga gatgtcatgg agaagatgag ccgttcccaa gtttcggctc taccaacttt
     4021 ttctgagcag attggacaaa agctctctta tcaccatgat gaagtagtca ttacagtgga
     4081 accctttatg ctagaaaaaa atggagtttt ggctaatggt gtattggcag aaattctgac
     4141 ccacatgacc caagatttag ttgttaatag tggtcgcaat ctcattatcg agcagatgct
     4201 gatctacttt ttgcaggctg ttcagataga tgatatattg cgcattcagg cacggattat
     4261 tcatcatacg agacggtcag ctataattga ttacgatatt tatcatggtc accagattgt
     4321 ttcaaaagca aatgtgactg ttaaaattaa ttagaaacta ggagaaaaga tgataacatt
     4381 aaaatcagct cgtgaaatcg aagctatgga caaggctggt gattttctag caagtattca
     4441 tataggctta cgtgatttga ttaagccagg cgtagatatg tgggaagttg aagaatatgt
     4501 ccgccgtcgt tgtaaagaag aaaatttcct tccacttcag attggggttg acggtgccat
     4561 gatggactat ccttatgcta cctgttgctc tcttaacgat gaagtggctc acgctttccc
     4621 tcgtcattat atcttgaaag atggtgattt gctcaaagtt gatatggttt tgggaggtcc
     4681 cattgctaaa tctgacctga atgtctcaaa attaaacttc aacaatgttg aacaaatgaa
     4741 aaaatacact cagagctatt ctggtggttt agcagactca tgttgggctt atgctgttgg
     4801 tacaccgtcc gaagaagtca aaaacttgat ggatgtaacc aaagaagcta tgtacaaggg
     4861 tattgagcaa gctgttgttg gaaatcgtat cggtgatatc ggtgcggcta ttcaagaata
     4921 cgctgaaagt cgtggttacg gtgtagtgcg tgatttggtt ggtcatggtg ttggcccaac
     4981 tatgcacgaa gaaccaatgg ttcctaatta tggtattgca ggtcgtggac tccgtcttcg
     5041 tgaaggaatg gtcttaacca ttgaaccaat gatcaataca ggcgattggg aaattgatac
     5101 agatatgaaa actggttggg cgcataagac cattgacggt ggattgtcat gtcagtatga
     5161 acaccaattt gtcattacga aagatggacc tgttatcttg actagccaag gtgaagaagg
     5221 aacttattaa taaaaagtga aaagactact ggaagtttat tttgataaaa aatccagtag
     5281 atcttttcat aataaaacgc attgtatcaa gtgttagggg ctgatatcat gcgtttttct
     5341 gcttttaaga ttttttccaa ctctgtttgt aagcgcatca taacaaaggg tctaggattc
     5401 agggctctcc tcctatatac tattagtaaa gtaaaactaa gggaggatat tttagtgtcg
     5461 cagtctattg ttcctgtaga gattccacaa tattgtcgtt ttgattctaa aaagagaaat
     5521 ggaattctgt ttaatgttcg tattgccaat cttaaattta cttttt
//
LOCUS       DAVMBH010000079         5132 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVMBH010000079 DAVMBH010000000
VERSION     DAVMBH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.079"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(56..1066)
                     /locus_tag="VYP30_002018"
     CDS             complement(56..1066)
                     /locus_tag="VYP30_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1808938.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVVGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VYP30_002019"
     CDS             1215..2384
                     /locus_tag="VYP30_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1808939.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAGKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VYP30_002020"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VYP30_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1808940.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VYP30_002021"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VYP30_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1808941.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIVGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VYP30_002022"
     CDS             4146..4379
                     /locus_tag="VYP30_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1808942.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VYP30_002023"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VYP30_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..>5132
                     /locus_tag="VYP30_002024"
     CDS             4918..>5132
                     /locus_tag="VYP30_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEV1808943.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGVARGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAA"
BASE COUNT         1542 a          949 c         1297 g         1344 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggataga aagagcgtga tagggataat ggccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggcgc gccaaccaca gggaagaatc ctcctaagta ccaagatagg atggaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcgggc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcgtgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagtggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatt
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaacc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt cgatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agtagcacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gc
//
LOCUS       DAVMBH010000080         4239 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVMBH010000080 DAVMBH010000000
VERSION     DAVMBH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.080"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1..490
                     /locus_tag="VYP30_002025"
                     /pseudo
     CDS             1..490
                     /locus_tag="VYP30_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            418..870
                     /locus_tag="VYP30_002026"
     CDS             418..870
                     /locus_tag="VYP30_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808944.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDRPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1689..2048
                     /locus_tag="VYP30_002027"
     CDS             1689..2048
                     /locus_tag="VYP30_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808945.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2058..2423
                     /locus_tag="VYP30_002028"
     CDS             2058..2423
                     /locus_tag="VYP30_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1808946.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYEQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2410..>4239
                     /locus_tag="VYP30_002029"
     CDS             2410..>4239
                     /locus_tag="VYP30_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1808947.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEMYNVNFSNNDKLYESRNDRQEKHQQTIHAHYLIQSFSPEDNLTPEEINR
                     IGYEIMMELTGGRFKFIVATHTDKDHVHNHILINAIDRNSDKKLIWNYALERNLRMIS
                     DRISKVTGAKIIEKRYSYRDYKKYRESSHKFELKQRLYFLLQQSKSFDDFLEKAKQLH
                     VQIDFSQKHSRFLMTDRTMIKPIRGRQLSKRDLYDEDFFKTYFAKQEIESRLKFLLKS
                     VYSLEELHVKAKELNLTIELKQKNVMFTLEEDGKKISLSHKKISDKKLYDVQFFNRYF
                     EDREVRDIQALENLQEDFQTFREEQHKEKVSAEEIEEAFKKYKEKRDAIHEFEIELTD
                     NQIEKLVDDGVYIQVSFGIKQSGLIFIPNYQLDIFEEDNHKKYKVYIRETSSYFVYNK
                     ENMDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLKEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMQLEETQEKIATLNKMAEVLINLKSEDHETRKLAKYDFDQMNMTES
                     IMLDRLNTDILKLQQELGNEINKYEEIARRLDLFVKIINTNKFT"
BASE COUNT         1547 a          632 c          836 g         1224 t
ORIGIN      
        1 ttagcagagg caatcataaa aaatggaata gaaatagttg tagtaactga tcataatact
       61 accaaaggta ttaaaaagtt acaaatggca gtctcaatca taatgaaaaa ttatccgatt
      121 tatgatatac atcctcatat tttacatgga gtagaaatta gtgcagcaga taaattgcat
      181 attgtatgta tatatgatta tgaacaagaa tcatgggtta atcaatggtt aagtgaaaat
      241 attataagtg agaaagatgg aagttatcaa cattcactga ctataatgaa ggatttcaat
      301 aatcaaaaaa tagttaacta tattgctcat ttcaatagtt atgacatttt gaaaaaaggt
      361 tctcacttat caggtgcata taaacgaaaa attttttcta aagaaaatac acgatttttg
      421 gagtttaata ttaactcgaa agaatcttcg caacaacttg atattctcta taaagaagtt
      481 ggtgtattaa gtttgggaca aaaagttgta gccatgcttg attttttatt agcatatagt
      541 gattattcta aagacttcag accattgatt attgatcggc ctgaagacaa tctagacaat
      601 cgttatattt acaggcattt agttcagcag tttagagatg tgaaagctca acgtcaaatt
      661 attttagcaa cacataatgc tacaattgta acaaattcta tgacagatca agttgttatt
      721 atggagtcag atggagttaa cggatggatt gaatcacagg gatatgttag tgaaaaatat
      781 ataaaaaatc atatcatcaa tcaattagag ggaggaaaag attccttcaa gcataaaatg
      841 tctatatatg agacggcttt atcagagtag agtcagaaaa agtaggttag aaatttagcc
      901 tacttttttc tttgtccgac aggcatagtg tacatctgag gtccaagtcc tctgtggatg
      961 tttgctgcag atgaaaccaa tagcgactcc taagcctgaa tatcgtgagg taggggggat
     1021 aggaaggaat tagcgaaatc aaggttctac aaacagaatc gcgacttgaa gccatatata
     1081 gcggatgagg aactctaaaa tccaaatagg tgtcgtaacc tatatacgta aattacgaga
     1141 gtaaactagg aaagatgtac ggcttattcc gtgagcgttt aggacgtagt acaacgaatc
     1201 atgggagtca gctgaacaca tagtattgaa gaaatttctg taatggaaat ggagcgaaga
     1261 agtgaacgat taaatgaata cctctctaat taaatttgtc aattctaatt cctggtatga
     1321 aaagacagtg acctgaaaat gtaaacgatg ggagctgatc ataaatatag gacggtacat
     1381 gcagtggtgt tagagattag tccttacttg atttgtgata acttccccaa atttcttctg
     1441 ctatactttt ctcaactttt aaaaatccaa ctaagaattt tacctggggg tttgggggcg
     1501 aagccaccaa gttatcttat cgttggctgt caaaactgga aggttttggt tagctggcga
     1561 tatgattttt tgggtattgt gatcacaatg cctgaactcg caaagaccga acaaggactt
     1621 taagaaattt cccgtatgac acacggggtc ggggtttacc cgagaaagga tgaaagtgag
     1681 gaaaagagat gtctgaacag taccgtgaca ttcgaaaaga ggtaaatcta accgcagatg
     1741 agctaaaaca gattgaaaaa atgatggagg ttgataatta tcgtcacttt tcaccattcg
     1801 tcagggataa aattttgatg actgatgaca aacagttagc tgccaaagaa tggttttccc
     1861 tttggcagtc tcaaaagttt gaacagatca gtcgagatgt gcatttggtt ttgattatcg
     1921 caagagagaa tcaccaagtg actcaagaac acgtgtcaat cttattgacc tgcgttcaag
     1981 aattgattgc ggaagtcaat caagtacagt cactcagtcg tgggtttcgt gaaaaataca
     2041 tgagatagga ggctactatg gtttatcgtt atcgtaccaa tctcaaaaaa gtatttctaa
     2101 cagattcaga attacaccaa ttgaatgaac ggattgctaa gagcaattgt caaaatttct
     2161 cagtctatgc cagaaaagtt ttgcttaatc ccaatatgtc atttgtcacg attaacactg
     2221 atacttatga acagttagtg tttgaattga ggaggattgg aaataacatc aatcaaattg
     2281 cgcgtgcgat taatcaaagc catctgattt ctcaggacca attacaagaa ttgagtaaag
     2341 gagtcggaga gttgatcaag gaagtggaca aagaatttca agtggaagtg aaaagattga
     2401 aggagtttca tggtagtcac taagcatttt gcgacacacg gaaaaaaata tcgtaggcgt
     2461 ttaattaagt atatcctcaa tcctgataaa acggacaatt tgaaattagt atctgatttt
     2521 ggcatgagca attacttgga cttccctagt catgcagaaa tggtagagat gtacaatgtc
     2581 aacttcagca ataatgacaa gttgtacgaa tccagaaacg accgacaaga aaaacaccaa
     2641 caaactattc atgctcatta cctcattcaa tcattttctc ctgaagataa tctgacacct
     2701 gaagaaatta accgcattgg ttatgagatc atgatggaat tgacaggagg tcgttttaag
     2761 tttatcgtag caactcacac agacaaagat catgttcata atcacatcct aatcaacgct
     2821 attgaccgca attcagataa aaagttgata tggaactatg ccttggaacg aaacctccgt
     2881 atgatttcag accgtatttc taaagtgact ggtgcaaaaa ttattgagaa acgttattcc
     2941 tatcgagatt ataaaaaata tagggaatct agtcataagt ttgaattgaa acaacgtctt
     3001 tattttttgc tacagcaatc taaatcgttt gatgattttt tagagaaagc aaagcagttg
     3061 catgttcaga ttgattttag tcaaaagcat agccgttttt tgatgacaga tagaacgatg
     3121 ataaaaccaa ttcgaggacg ccaactcagc aaacgagatt tatatgatga agactttttt
     3181 aaaacatatt ttgccaaaca agagattgaa agtcgtttaa aatttttact aaagtctgtt
     3241 tattcattag aagaattgca tgtaaaggct aaagagttga atctaaccat cgagttaaaa
     3301 cagaaaaatg tgatgtttac cctagaagaa gatggcaaaa agataagcct gagtcataaa
     3361 aaaattagcg ataagaaatt gtacgatgtt caatttttta atcgttattt tgaagataga
     3421 gaagttagag atattcaagc attagaaaat cttcaggaag attttcagac ttttcgagag
     3481 gagcagcata aggagaaagt ctccgctgaa gaaatcgagg aagccttcaa gaaatacaag
     3541 gaaaaacgag atgctatcca tgagtttgag attgaactta cggataatca gatagagaag
     3601 ttggttgatg atggtgtcta tatacaggtt tcgtttggta tcaaacagag tggactcatc
     3661 tttattccta actaccagct agatattttt gaggaagaca atcataaaaa atataaagtc
     3721 tacattcgag aaacgtcttc ttactttgtc tataataaag aaaacatgga taataattgt
     3781 ttcatcaagg gtaggacctt aatcagacaa ttgagcaacg atagccaaaa actcccctat
     3841 agacgaccaa ctttaaaaag tcttaaagag aagatttctg aaattaatct tatgattgaa
     3901 ctatctaaca cgaacaaaca ataccaagaa atcaaagatg agcttgtatt agaaattgca
     3961 gagattgata tgcagctaga agaaacccaa gaaaaaatcg ccaccttaaa caagatggcg
     4021 gaagtcctta tcaatttgaa gagtgaagat catgagacta gaaaattagc taagtatgat
     4081 tttgaccaaa tgaacatgac ggaatcaata atgttagatc gactcaatac ggatatttta
     4141 aaattacaac aggaacttgg taatgaaatt aataaatatg aggagatagc tagaagattg
     4201 gatttgtttg tgaaaattat taataccaat aaatttaca
//
LOCUS       DAVMBH010000081         4192 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVMBH010000081 DAVMBH010000000
VERSION     DAVMBH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4192
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.081"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            720..1712
                     /locus_tag="VYP30_002030"
     CDS             720..1712
                     /locus_tag="VYP30_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1808948.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VYP30_002031"
     CDS             1714..2532
                     /locus_tag="VYP30_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1808949.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VYP30_002032"
     CDS             2534..3319
                     /locus_tag="VYP30_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808950.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3417..3635
                     /locus_tag="VYP30_002033"
     CDS             3417..3635
                     /locus_tag="VYP30_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1808951.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3620..3817
                     /locus_tag="VYP30_002034"
     CDS             3620..3817
                     /locus_tag="VYP30_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1808952.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1165 a          719 c          904 g         1404 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca aactcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagcaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccagact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tttccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ttggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aatttctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagga acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaggc agttgtcgct gagattttga
     3421 aggatttgcc agaatggttt ggaatcccag aaagcacaca aacctatata gaaggaacca
     3481 cgacactgca agtttggacc gcctatcagg agagtgattt gactggattt gtaagcttat
     3541 cctattcgag tgaagattgt gcagagattg attgtctcgg cgtaaaaaag cttatcaagg
     3601 tagaaaaatt gggagccaat tgcttgctac tttagagagt gaagctcgta aaaaagttgg
     3661 ttatctgcag gtcaaaacag tggcagaagc ttctaataaa gattatgatc gaacaaatga
     3721 cttttatcga ggtcttggct ttaaaaagtt agagattttt cctcaactat ggaatccgca
     3781 aaatccttgt cagattttga ttaaaaagct tgaataatat tacttgacat ctatttttta
     3841 ttctcagagt gctatactgt aagtgtaatc gccgatttag ctcagttggt agagcaaggc
     3901 actcgtaaag cctaggttat aggtagataa acgactgagg agttgaaaaa atagataggt
     3961 agaagataac cgttaagcct tattcttagc ggttatttat attgtttaat agcgctgata
     4021 tttcatcaat tatgcctgtt ttcgtgtttc cggtagttgt tcaagtttat tgctactatt
     4081 tttgatggta tgaatgtgct tataatgtat cccggttaac gaaagttttg gacttatact
     4141 cttagaaaat ctcttcaaac cacgtcaacg ccgccttgcc gtgcgtatgg tt
//
LOCUS       DAVMBH010000082         3849 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVMBH010000082 DAVMBH010000000
VERSION     DAVMBH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3849
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.082"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..423
                     /locus_tag="VYP30_002035"
     CDS             <1..423
                     /locus_tag="VYP30_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1808953.1"
                     /translation="VRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVENSVINAKIADAEALLEKVTDPSIRQNAMET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
     gene            633..3752
                     /gene="phtE"
                     /locus_tag="VYP30_002036"
     CDS             633..3752
                     /gene="phtE"
                     /locus_tag="VYP30_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1808954.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKIDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEEVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQQSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNSSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1441 a          624 c          753 g         1031 t
ORIGIN      
        1 gttcgtaaaa ataaggcaga ccaagacagt aaacctgatg aagataaggg acatgatgaa
       61 gtaagtgagc caactcaccc tgaatctgat gaaaaagaga atcacgctgg tttaaatcct
      121 tcagcagata atctttataa accaagcact gatacggaag agacagagga agaagctgaa
      181 gataccacag atgaggctga aattcctcaa gtagagaatt ctgttattaa cgctaagata
      241 gcagatgcgg aggccttgct agaaaaagta acagatccta gtattagaca aaatgctatg
      301 gagacattga ctggtctaaa aagtagtctt cttctcggaa cgaaagataa taacactatt
      361 tcagcagaag tagatagtct cttggctttg ttaaaagaaa gtcaaccggc tcctatacag
      421 tagtaaaatg aatggagcat attttatgga gaagtaacct ttcgtgttac ttctcttttt
      481 tagaaaaacg taacagaaac ttgacaaaag taattttaaa tagtaaacta tttactggtt
      541 aattaaatgg ttaaataacc ggtttagaaa actatttaat aaagtaaaag aagttgagaa
      601 aaaacttcat catttattga aatgagggat ttatgaaatt tagtaaaaaa tatatagcag
      661 ctggatcagc tgttatcgta tccttgagtc tatgtgccta tgcactaaac cagcatcgtt
      721 cgcaggaaaa taaggacaat aatcgtgtct cttatgtgga tggcagccag tcaagtcaga
      781 aaagtgaaaa cttgacacca gaccaggtta gccagaaaga aggaattcag gctgagcaaa
      841 ttgtaatcaa aattacagat cagggctatg taacgtcaca cggtgaccac tatcattact
      901 ataatgggaa agttccttat gatgccctct ttagtgaaga actcttgatg aaggatccaa
      961 actatcaact taaagacgct gatattgtca atgaagtcaa gggtggttat atcatcaaga
     1021 tcgatggaaa atattatgtc tacctgaaag atgcagctca tgctgataat gttcgaacta
     1081 aagatgaaat caatcgtcaa aaacaagaac atgtcaaaga taatgaggag gttaactcta
     1141 atgttgctgt agcaaggtct cagggacgat atacgacaaa tgatggttat gtctttaatc
     1201 cagctgatat tatcgaagat acgggtaatg cttatatcgt tcctcatgga ggtcactatc
     1261 actacattcc caaaagcgat ttatctgcta gtgaattagc agcagctaaa gcacatctgg
     1321 ctggaaaaaa tatgcaacag agtcagttaa gctattcttc aacagctagt gacaataaca
     1381 cgcaatctgt agcaaaagga tcaactagca agccagcaaa taaatctgaa aatctccaga
     1441 gtcttttgaa ggaactctat gattcaccta gcgcccaacg ttacagtgaa tcagatggcc
     1501 tggtctttga ccctgctaag attatcagtc gtacaccaaa tggagttgcg attccgcatg
     1561 gcgaccatta ccactttatt ccttacagca agctttctgc cttagaagaa aagattgcca
     1621 gaatggtgcc tatcagtgga actggttcta cagtttctac aaatgcaaaa cctaatgaag
     1681 tagtgtctag tctaggcagt ctttcaagca attcttcttc tttaacgaca agtaaggagc
     1741 tctcttcagc atctgatggt tatattttta atccaaaaga tatcgttgaa gaaacggcta
     1801 cagcttatat tgtaagacat ggtgatcatt tccattacat tccaaaatca aatcaaattg
     1861 ggcaaccgac tcttccaaac aatagtctag caacaccttc tccatctctt ccaatcaatc
     1921 caggaatttc acatgagaaa catgaagaag atggatacgg atttgatgct aatcgtatta
     1981 tcgctgaaga tgaatcagga tttatcatga gtcacggtaa tcataatcat tacttcttca
     2041 agaaggactt gacagaagag caaattaaag ctgcgcaaaa acatttagag gaagttaaaa
     2101 ctagtcataa tggattagat tctttgtcat ctcatgaaca ggattatcca ggtaatgcca
     2161 aagaaatgaa agatttagat aaaaaaatcg aagaaaaaat tgctggcatt atgaaacaat
     2221 atggtgtcaa acgtgaaagt attgtcgtga ataaagaaaa aaatgcgatt atttatccgc
     2281 atggagatca tcatcatgca gatccgattg atgaacataa accggttgga attggtcatt
     2341 ctcacagtaa ctatgaactg tttaaacccg aagaaggagt tgctaaaaaa gaagggaata
     2401 aagtttatac tggagaagaa ttaacgaatg ttgttaattt gttaaaaaat agtacgttta
     2461 ataatcaaaa ctttactcta gccaatggtc aaaaacgcgt ttcttttagt tttccgcctg
     2521 aattggagaa aaaattaggt atcaatatgc tagtaaaatt aataacacca gatggaaaag
     2581 tattggagaa agtatctggt aaagtatttg gagaaggagt agggaatatt gcaaactttg
     2641 aattagatca gccttattta ccaggacaaa catttaagta tactatcgct tcaaaagatt
     2701 atccagaagt aagttatgat ggtacattta cagttccaac ctctttagct tacaaaatgg
     2761 ccagtcaaac gattttctat cctttccatg caggggatac ttatttaaga gtgaaccctc
     2821 aatttgcagt gcctaaagga actgatgctt tagtcagagt gtttgatgaa tttcatggaa
     2881 atgcttattt agaaaataac tataaagttg gtgaaatcaa attaccgatt ccgaaattaa
     2941 accaaggaac aaccagaacg gccggaaata aaattcctgt aaccttcatg gcaaatgctt
     3001 atttggacaa tcaatcgact tatattgtgg aagtacctat cttggaaaaa gaaaatcaaa
     3061 ctgataaacc aagtattcta ccacaattta aaaggaataa agcacaagaa aactcaaaac
     3121 ttgatgaaaa ggtagaagaa ccaaagacta gtgagaaggt agaaaaagaa aaactttctg
     3181 aaactgggaa tagtactagt aattcaacgt tagaagaagt tcctacagtg gatcctgtac
     3241 aagaaaaagt agcaaaattt gctgaaagtt atgggatgaa gctagaaaat gtcttgttta
     3301 atatggacgg aacaattgaa ttatatttac catcgggaga agtcattaaa aagaatatgg
     3361 cagattttac aggagaagca cctcaaggaa atggtgaaaa taaaccatct gaaaatggaa
     3421 aagtatctac tggaacagtt gagaaccaac caacagaaaa taaaccagca gattctttac
     3481 cagaggcacc aaacgaaaaa cctgtaaaac cagaaaactc aacggataat ggaatgttga
     3541 atccagaagg gaatgtgggg agtgacccta tgttagatcc agcattagag gaagctccag
     3601 cagtagatcc tgtacaagaa aaattagaaa aatttacagc tagttacgga ttaggcttag
     3661 atagtgttat attcaatatg gatggaacga ttgaattaag attgccaagt ggagaagtga
     3721 taaaaaagaa tttatctgat ctcatagcgt aaggaatagc agtagaaaaa gtctgaatca
     3781 aaaatgaagt tctctcaaaa gttagaaata aaactctgac tttgggagaa tttcatttta
     3841 ttattaata
//
LOCUS       DAVMBH010000083         3773 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVMBH010000083 DAVMBH010000000
VERSION     DAVMBH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.083"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..452)
                     /locus_tag="VYP30_002037"
     CDS             complement(<1..452)
                     /locus_tag="VYP30_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1808955.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQ"
     gene            complement(445..1173)
                     /locus_tag="VYP30_002038"
     CDS             complement(445..1173)
                     /locus_tag="VYP30_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1808956.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(1207..1377)
                     /locus_tag="VYP30_002039"
     CDS             complement(1207..1377)
                     /locus_tag="VYP30_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808957.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(1390..3513)
                     /locus_tag="VYP30_002040"
     CDS             complement(1390..3513)
                     /locus_tag="VYP30_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV1808958.1"
                     /translation="MTGKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEKG
                     RDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLIAFWDNQHYVVIYKVKKNKV
                     YIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKGR
                     LILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILARS
                     MGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVVG
                     GVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSLI
                     YSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQLF
                     APIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRVN
                     DIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVGQ
                     SGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSILD
                     NITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARAL
                     INNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGGK
                     IVESGNHKYLMDLGGEYYSLYTKRK"
     gene            complement(3513..>3773)
                     /locus_tag="VYP30_002041"
     CDS             complement(3513..>3773)
                     /locus_tag="VYP30_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NukM"
                     /protein_id="HEV1808959.1"
                     /translation="LCHGSVGTISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPEL
                     STDLNTMNTFSFMLGVSGVVYEISRKQDDRLLNVLLLELKRT"
BASE COUNT         1338 a          664 c          429 g         1342 t
ORIGIN      
        1 aattgaatgg taaatgtttt taaaaagaaa atcaaaccaa tctctaaact gttatcaata
       61 gccttcccaa taacgtataa gctaatataa tcagacaacc aaaaagtaaa tgtgtaaacc
      121 actgtaatga gtaatttaga atttattgtg tacttgtttc taaatggcaa tgaaattacg
      181 gttaaccatg catcattttt aaattctact gcaaacactt cgtaaattat taaagataga
      241 actaaataaa atagttcaga aaaataaaat attgtttgtt ctttaaaaat taactgccaa
      301 ttagataaag caagttcatt ttgatgcacc aataaataac ctcgatacct aaaagttaag
      361 tctatatata acaaagcatt cagaattatt ggaaaaataa gaacaaacca taagatgctt
      421 tttttctgct ttagaaactc taatttaatc atattcacct ccagctaaac aagctaagta
      481 ggcttcttcc agatttcgac aattatactt ttgtaaaagg tagtggcaag aaccaaaaaa
      541 ttcaactttc ccataattta taattataat atcagatatc actttatcca gttcactaag
      601 aatatgactt gatattaaaa atgtaatacc ttttttctcc tgtagaaaac ggattaaact
      661 tctaatttca attacaccct gtggatcaag tccattgatt ggttcatccc aaattaatat
      721 ttctggacta cctaacaatg atgcagctat acttagacgt tgtttcatgc ccattgaaaa
      781 atttttcact tttttctttt taacatcttt taatcctacc attgatagat attcattaag
      841 tctttcagta tctaaactaa gccctttcat atttgctatt aacttcaaat ttttataagc
      901 atcaagatga ccataaaatg aaggtcccaa aactaatcct atcctagata atatattttc
      961 ggaattctgt tctacggttt gattaaaaat agttattttc ccagaatctg gttttaaaat
     1021 ccctagaatc attttgataa ttgtagtttt tccagcccca tttggtccaa caaaaccata
     1081 tacttttccc ttatttaaat aaaatgaagt gttatgaata acttcaatat ctttaaagct
     1141 ttttgttaga tttataattt caactatagc catctctact ccttagttta cagcaaaaaa
     1201 ttatgcttaa ttcttattgt ttttgtaaaa aatcagcgaa cccaatacta ttccattcaa
     1261 caaacctaaa gaaatagcat attcaactgg aaaatctaaa aaaattgcaa atactattcc
     1321 aatcatcacc cctagtgagg ctgctgttga aattacatat tcatttactt tcttcatttt
     1381 ctttacacct catttccttt ttgtatataa gctgtagtac tctccaccaa gatccattaa
     1441 gtacttatga tttcctgact caacaatctt accacctttc attacaaaaa taatatccgc
     1501 atccttaatc gttgacaatc tatgagctat aattatttga gtacaaccct gactttgtat
     1561 atactttgtt attctttcct cattaatagt gtctaatgca ctagttgctt catctaaaat
     1621 tacaatacta ggattattta ttaatgcacg tgccagtgct atccgttgcc tttgcccacc
     1681 tgaaatattt gaccccatct ctgagatgat agtattaaat ttcatcggca tagccatgat
     1741 ttcatcatag atttgaactg ctttacaaac ttcctctatc ttttgtgaag taacttcgtt
     1801 ctttaaagtt atattatcaa gaatacttcg gttcaataaa aatgaatcct gtggaactac
     1861 tcctaaattt tgacttaata tttttttatc tatttgatta atatttacac catcaaataa
     1921 aatttttcct gtatcaatct tatataatcc tgatagtatt tttgataacg tactttttcc
     1981 tgaccccgat tgaccgacta gtgcaattct ctgtcctggc tcaatagtca aatttaaatt
     2041 ttctattaca ggagctgagt ctttggaata agagaaagat aggtccttaa tatctattct
     2101 accttctaaa gaacactttt taagaccatt ttcaacattc tcttcatttt caagccagat
     2161 atcatttact ctatttaagt atcctgctgc caaaatatac tgcgtataag cattaaatat
     2221 tgagatttct gaactaaata aaattgatgc catggtttga aatgcgacaa cctcacccaa
     2281 taaaattttt ccatttaaaa cattatcaag tccaaaaatc aatataatta taggagcgaa
     2341 caattgaaat acattagtag ctgaattgta taaaatatgc acaatacttc gttttttata
     2401 ctttgtcaat acgtttttta aatacttaga ccagttttca tatatttcat cttctaatcc
     2461 cgatattttt attgaagaaa tagtatttaa tgcttctgtt tctactgagt aaatcaatga
     2521 ttgttcttgt aattctctat taaccgtatc atacattatt tttctagtac taaacagaaa
     2581 caaaaaattg attaaactca atataagagc tataattgat aatgtttttg aactaagaaa
     2641 catatatatt acaacactta gaatagtccc gatatctact actcccccaa caacttggtt
     2701 agtaaatagc tccctaaaac cactaagact agaaattctg tataaaatat ctccttttgc
     2761 cctgagttca aaaaaactat atggtagttt aagcaaatgc ttaaatgtaa aactttcaat
     2821 atctctacta aaaaatatat tagaaaatag aattcccata ctcctagcca agatagaaat
     2881 aagatacaaa caaagtagag aaaataaaat taaaaacgag gtttgaaaag aaaatgtatt
     2941 ccctaatgca gaattaataa actttgaagt cattactggt acggaaagta ttattaagta
     3001 acttattatt gaaaatagta acgtcaaaat caatcgacct tttacctttg aaaaactaga
     3061 gaatactctt atccatggag aaggaaactg cgacttcaaa gattgataat tttcgttagg
     3121 aaatgatagc agtactatat tactaaaatg ttttgaaaac tccttaaact cataatttat
     3181 atatccttta gaaggatcca ttatatagac cttattcttt tttactttgt aaataactac
     3241 ataatgttga ttatcccaga atgctattaa tggtaacgga agttcactaa ttttatttac
     3301 atctttaact tgatatgagc cagtatcaaa atttcgttta ttcaataact gtttcaagtc
     3361 acctatacta taaccatctc tccctttttc tatatcacgt cttaaatcta gtaatgtctc
     3421 tttgctttta tagaaatgta gtatggacaa gcagcaacat aaaccacatt ctatttgaga
     3481 catttgctca atattaggta cttttccagt catcatgtcc tctttaactc cagtaataaa
     3541 acattaagta atctatcatc ttgttttcga gatatttcat agacaactcc agatactccc
     3601 agcataaaag aaaatgtatt catagtattc aaatccgtac ttaattctgg tttgataacc
     3661 tgagaaacga cattatcaaa ataaaaatct atagattctt ttattaatag gttttcttca
     3721 tctttcaata ttgcatcaag acaactgata gtacctacag aaccgtgaca taa
//
LOCUS       DAVMBH010000084         3191 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVMBH010000084 DAVMBH010000000
VERSION     DAVMBH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3191
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.084"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            40..1584
                     /locus_tag="VYP30_002042"
     CDS             40..1584
                     /locus_tag="VYP30_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1808960.1"
                     /translation="MLIYAATINALVLNELIAMNLERFLKLSIYQMIVWCGIIFLDWV
                     VKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLNDQAFKQ
                     LFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFASKMREVSLNLTSQN
                     EAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAGAISFFL
                     NIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGGQLSSIIGTKPIFL
                     KLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEILKNLNFCFQRNEKYLI
                     LGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMVSNVLYVDQKAYLFEGT
                     IRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDDGRLLSGGQKQKITLAR
                     GLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTHAPHPELKQYFTKIYQ
                     FPKDFI"
     gene            1845..2273
                     /locus_tag="VYP30_002043"
     CDS             1845..2273
                     /locus_tag="VYP30_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808961.1"
                     /translation="MSEIVEMSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            2285..3034
                     /locus_tag="VYP30_002044"
     CDS             2285..3034
                     /locus_tag="VYP30_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1808962.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            3047..>3191
                     /locus_tag="VYP30_002045"
     CDS             3047..>3191
                     /locus_tag="VYP30_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1808963.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNE"
BASE COUNT         1123 a          367 c          588 g         1113 t
ORIGIN      
        1 tttagtttat taacgatatt tattgttgct ggtcaattat tgctaattta tgcagcaact
       61 attaatgctc tggtgttgaa tgaattaatt gcgatgaatt tagagcggtt tttgaaattg
      121 tcaatctacc aaatgattgt ctggtgtggg ataatattcc ttgactgggt agtgaaaaat
      181 tatcaggttg aagtgatcca agagtttaat ctagagattc gaaatagagt tgccacagac
      241 atctctaact ctacctatca agaatttcat agtaaatcat caggaacata tctttcgtgg
      301 ctaaataatg atgttcagac tttaaatgat caggctttta aacaactttt tttagtaata
      361 aaaggaattt ctggtactat atttgcagtt gtgactctta atcactatca ttggtcattg
      421 actgtagcca ccttgttttc attaatgatt atgctacttg taccaaaaat ctttgcatcg
      481 aaaatgcgag aagttagtct aaatttaact agccaaaatg aagctttttt aaaatctagt
      541 gagactatat tgaatggatt tgatgtgtta gcgtccttga atcttttata tgtattgcct
      601 aagaaaatta aagaagcagg aattttatta aagatggtta tacaaagaaa gacaactgta
      661 gaaacgttag caggcgctat tagcttcttt ctcaatattt tttttcagat atctctcgtt
      721 tttttaacag gctatcttgc aataaaagga atagtgaaaa ttggtactat tgaagcaata
      781 ggagcactaa caggtgttat ttttacagcg ctaggtgaat taggaggtca attatcctct
      841 attattggta cgaagcctat ttttttaaaa ttgtattcaa ttaatccaat tgagtcaaat
      901 aaaatgaatg atatcgaacc aaatgaggtg aatagagatt ttccgttata tgaagcaaaa
      961 aatatttgct ataagtatgg agataaagaa atattaaaaa acttaaattt ttgttttcaa
     1021 cgtaatgaaa agtatttaat tttaggtgaa agtggaagcg ggaaatctac attattaaaa
     1081 ttattgaatg gctttttgag agattatagt ggagaattgc gattctgcgg ggatgatata
     1141 aaaaaaacct cctatttaaa tatggtttcg aatgttctat atgtagatca aaaagcttat
     1201 ttgtttgaag gtacgattag agataatatt ttattggaag aaaattatac tgatgaagaa
     1261 atactacagt ctttagaaca agttggtttg agtgtaaaag attttcctaa taacatttta
     1321 gattattatg ttggtgatga tgggagatta ctgtcaggag ggcagaaaca aaaaattact
     1381 ttagctagag gcctaattag aaataagaaa atagtattaa ttgacgaggg aacttctgct
     1441 atcgatagga gaacttcgtt agcgattgaa cgtaagatat tagatagaga ggatttgact
     1501 gtcattattg ttacccatgc tccgcatccg gaacttaaac aatattttac taagatatat
     1561 caatttccaa aggattttat ttaagaatat aggggaggga aacatgagat tctattgtga
     1621 agcttatgag gtaattactg aagagaaaaa agtatcattt ttttatgtag atgagaaacc
     1681 cttaaggtat ctgttatttg actatatatt tctactagtt ctagctaaaa aaaaatatcc
     1741 caatcttatg aactgcaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     1801 tcattttgca tagttttggc attcatccta gatatccata taaaatgtct gagattgttg
     1861 aaatgtctaa aaaaatatca aatctaaacg ataaaaaaga atttcacaaa aagaactgtg
     1921 agttgaggtt tcaagatagt gttcttgata acataaatag tgtcccgggt acaactcatt
     1981 tatttagttg tttaaatatt caaacattag taaaaattat tttatatatt tttcgataca
     2041 acagttgtat gaaaatattt aattttagag ataaagagct tatctttttt aataagattg
     2101 taaatgggct gatacaaaat attgaggaga atttagagga tgatattgaa aggatattga
     2161 aatatttata tatatgttta tttaacgaaa tattcattat taagaataag gtgaattttt
     2221 ttgatgatgt ggaatttaat cagacactta gtgagttttt agataaattg tagagggaat
     2281 ggttatgagt aacaatacta agtatatctt tttatctcca catttagatg acgcaatttt
     2341 ttcctgtggt gattatattt caaaattaac ttcagaagga gaaattgtac ttgttattac
     2401 tatattttct ggttaccctt tgagccaaca gctacagccc tctgctaagc aatttcataa
     2461 gttgtgtaac cttgggaaat atccgattga agaaaggaag aaagaagaca ggttagcttg
     2521 tgaacgtcta caatgtgatt ttagacactt atcgtactat gaatgtctct ataggaaaga
     2581 tagaaatggc aattttctat accgtcatat ctatagtgaa ttaaaaaatg aggacacatt
     2641 aaagaatgat atcataaaag agctgttaat gcatttagac gacaaatgtg tcgtatattg
     2701 tccgctttca cttggtgacc atgttgatca tgtttttgtg aatagtattg gaagggcgct
     2761 tgaatttatg cgttataaag taatatatta tgaggacttc ccatatgtaa gtgatagtag
     2821 tatggttagt tatatgggaa aaactaaaga attaaaaatg tatcaagagg aacttgatga
     2881 aaaacattat attgatagaa tatcatcaat attgtgctat aaatctcaga ttttgataat
     2941 ctggaaatca gttgaaaaac ttttaaacaa tattaaagag ttgtatttaa ggaatggggc
     3001 agcttattct attagatttt ggattaagaa ataaggaagt agttttatga atatagcagt
     3061 aattggtttg gggcatgttg ggctggccta cgcgttacta tttgcatcta aatataaagt
     3121 tgttgcatat gatatagatt ctgtaaaaat aaataattta aaaaagggca ttcttccatc
     3181 taaaaatgaa g
//
LOCUS       DAVMBH010000085         3089 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVMBH010000085 DAVMBH010000000
VERSION     DAVMBH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.085"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(278..811)
                     /locus_tag="VYP30_002046"
     CDS             complement(278..811)
                     /locus_tag="VYP30_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1808964.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(900..1676)
                     /gene="recX"
                     /locus_tag="VYP30_002047"
     CDS             complement(900..1676)
                     /gene="recX"
                     /locus_tag="VYP30_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1808965.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQNFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1714..3069
                     /gene="rlmD"
                     /locus_tag="VYP30_002048"
     CDS             1714..3069
                     /gene="rlmD"
                     /locus_tag="VYP30_002048"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1808966.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          980 a          546 c          555 g         1008 t
ORIGIN      
        1 ttttgatacg aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa
       61 acgatataag tttgttgtaa acttactagg aataaagaca ttaaaaaata atagtatatc
      121 tatttgtttt atatatttta cgaattctgc ataaatctct ttctagtaat gtgttgtaac
      181 tctgctataa tggatttatt cctttttgtg tttacacaat ttattttata ctaccaaaaa
      241 aacaaggtca ggattttgtt cctgaccttt gacaacttta ccgattcttt agttctacat
      301 agcgcttgta ccaaatgttt acataggctt ctgagaaagg accacgtcca ttgttaatcc
      361 aatcaacaag aattttgaca tgttctttta aaatatagtc caagtcatca gaataattca
      421 ttttgcgttt gtgacgctcg tactcttcaa cgtccaagag acgtttttcc ccatctgtaa
      481 aaattttaac atccaaatcg taatcaatat acttcagtgc ttcttcatcc agatagtagg
      541 ggctagccat attgcaatag taagaagttc cattatcacg aatcatggca atgatattaa
      601 accaatattt cttgtgaaag taaacaatag ccggttctcg agtgacccaa cgacgaccat
      661 cactttcggt aacaagtgta tgatcgttga caccaataat ggcgttttct gttgttttta
      721 gtaccatggt gtcccgccaa gttcggtgga gactcccatc atgcttataa ctttgaattg
      781 taataaagtc gccttctttt ggaagcttca taactaacca actttctaca atttataagt
      841 ttatcattta ctattgtacc ataaaattac ctaaaatctg tgaatttcac ttggaaatat
      901 taaagatatt ctctaagagc gcttgctata tccgaaaaat cgtagccctt tcgtgctaaa
      961 acttgagtta aacgctgctt cagttcgtat ccttcatact ttcgagcata cttagtatat
     1021 tgcttatcaa gttccttgaa gatgagttct tgagtcgttt cttggtcaac ttggctatct
     1081 aagtcgtcaa aggcaatttt agcatcagaa taagagaagc ccttgttagt caagttctgg
     1141 ataatcttat cttgcagggc acgagctgga agttttccct catatttttt caatagttta
     1201 ttagctacac gttgagcaac ttcagaaaaa tcaaattctt tcaagttctc ttctatagta
     1261 gattttgaaa tccctttttg agctagtttc tgagtcagca cataaggacc cttgtctcct
     1321 gaaagttgat tggtattgat gatagcataa gcgtactgac catcattaat ccacttatct
     1381 tctttaagat tagcaataac ttgagaaacg atgtttttat caatatcgta ttttttcaga
     1441 tattctctga cttctttttc agtgcgtgct ttaaaggata agtggtagag ggccagattc
     1501 ttaccataag aaaattgagc aaagttctga atctctttca attcctcttc gcttatcacc
     1561 ttatctctcg ataacataaa acgaacaatt gtatcttcgg tgatatagca tttgtcgcca
     1621 ttatcaagct ccatcagata gagtcttttt ttcttttcaa gttttgtgat tttcatagct
     1681 ctattataac tcaaaatgtg ataagatagg ggtatgaatc tgaaagtgaa acaaaaaata
     1741 ccattaaaaa tcaagcgcat gggaattaac ggtgagggaa tcggctttta ccaaaaaaca
     1801 ttagtctttg taccaggagc tctcaaaggc gaagatatct attgtcagat tacttctatt
     1861 agacgcaact ttgttgaagc aaaattactg aaggtcaaca agaagtctaa atttcgaatt
     1921 gtgccatctt gtactattta taatgaatgc ggaggctgcc aaatcatgca cctgcattat
     1981 gataagcagc tggagttcaa gacggactta cttcatcaag cgctgaaaaa atttgctcct
     2041 gcaggatatg aaaattatga aattcgtcca actattggaa tgcaggaacc aaaatattac
     2101 agagctaagt tacaatttca gactcgaaaa tttaaaaatc aggtcaaggc gggcttatat
     2161 gcacaaaact ctcactattt agtagagttg aaagactgcc tggtacaaga taaggaaacc
     2221 caagtgattg ctaatcgctt agcagaatta cttacttatc accagattcc aatcacggat
     2281 gagagaaaag ttctaggtgt ccgtactatt atggtccgac gcgcgagaaa gaccggacag
     2341 gttcagatta ttattgttac aaaccgccag cttaatttaa ctcaattggt aaaagagttg
     2401 gttaaagatt tcccagaagt tgtgacagta gctgttaata caaatacagc taaaaccagt
     2461 gagatatatg gtgaaaagac agagattatc tgggggcaag agagtattca agaaggtgta
     2521 ctcaattatg aattttcact atcccctcga gctttttatc aactaaatcc tgagcaaaca
     2581 gaagtcctct atagcgaagc agtaaaagcg ctggatgttg ataaagaaga ccatttgatt
     2641 gacgcttatt gtggagttgg aacgattgga tttgcctttg caaagaaagt aaaaacactc
     2701 agaggtatgg atattattcc agaagctatt gaagatgcca agcgaaatgc taaaagaatg
     2761 ggatttgaca atactcatta tgaagctgga acggcagaag agattattcc tcgttggtac
     2821 aaggaaggct accgagcaga tgctttgatt gttgacccac cacgtacagg tctggatgat
     2881 aagttattag atactattct tacttatgta ccagaaaaaa tggtttatat ttcttgtaat
     2941 gtttcgacct tggctcgtga tttggtacgc ttagtagaag tctatgatct tcattatatc
     3001 cagtcggtcg atatgttccc acatacagct cgaactgaag ctgttgtaaa attaataaaa
     3061 aaagtttaaa aaaggtgttg acaaaacat
//
LOCUS       DAVMBH010000086         2904 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVMBH010000086 DAVMBH010000000
VERSION     DAVMBH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.086"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(199..570)
                     /locus_tag="VYP30_002049"
     CDS             complement(199..570)
                     /locus_tag="VYP30_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808967.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQIMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLIIILFLIWGLKYYKK"
     gene            complement(1038..1157)
                     /locus_tag="VYP30_002050"
     CDS             complement(1038..1157)
                     /locus_tag="VYP30_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1808968.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(1261..1410)
                     /gene="blpO"
                     /locus_tag="VYP30_002051"
     CDS             complement(1261..1410)
                     /gene="blpO"
                     /locus_tag="VYP30_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1808969.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(1654..1857)
                     /gene="blpN"
                     /locus_tag="VYP30_002052"
     CDS             complement(1654..1857)
                     /gene="blpN"
                     /locus_tag="VYP30_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1808970.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(1873..2127)
                     /gene="blpM"
                     /locus_tag="VYP30_002053"
     CDS             complement(1873..2127)
                     /gene="blpM"
                     /locus_tag="VYP30_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1808971.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(2277..2904)
                     /locus_tag="VYP30_002054"
                     /pseudo
     CDS             complement(2277..2904)
                     /locus_tag="VYP30_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          980 a          602 c          399 g          923 t
ORIGIN      
        1 attcatagaa ctatagtaaa atgaaataag aacaggataa atcgatcagg acagtcaaat
       61 cgatttctaa caatgtttta gaagtagagg cgtactattc tagtttcaat atactatacc
      121 atattttgtt tcgcagggaa tctattataa aagggtaagt atttcaaaaa cacttacccc
      181 tttatacttt attaagctct actttttata atacttcaag ccccaaatga gaaaaagtat
      241 aataatcaag cagagaatag caccaatgta ggcaattatt tgttggtagg attctcctgc
      301 tgtgatccct ctatacaaac aaataataga cataaaacct gtcaagccga tgaacatgat
      361 ttgattagtt ctaggactaa ccaaatcatc gtcttcaaac tcttttatcc gcatttccct
      421 agtgaggtaa acagtgacca aaatagaagc taagttaata accactaaaa gaaattggaa
      481 aactgacgaa atagaaatag ataagtagaa acaagcaaag gcaactgacc caggaacaat
      541 ctcacaaaga atatgattct ttttaatcaa gaaaatcttt catttctttt ctttctttct
      601 aattaaagaa aaatagatca taaccgcaat catataggct atggtataaa atagattata
      661 ccaaatactc tccctaagcg gataaagaaa gatggacatg atcagataca gaacgaaaat
      721 aatcagtatt tttttcttca taagatttcc tcctaaatgt gcgatttatc ttagttgagc
      781 aagaacattt acactgctag tatagcactt attttgacct tggatcactc aaatcataaa
      841 tggtcatcaa aacctcttga attgtaaaaa ttaaaaaagc aagcatgaaa aacatacttt
      901 cctctttata ttgtattgat accaacttgt ttgtagactt ttcatcctgc tatcacatat
      961 cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct agcaaataca
     1021 ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga ttttgaaaat
     1081 atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa accaataata
     1141 aaacttttaa aatccataat taccaccaac atattgctgc ataggctaca cctccaagta
     1201 tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc aatagaaatg
     1261 tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg cacaactaat
     1321 ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat tatccataac
     1381 tgcaaattgt gacatcattt ttgtatccat atagtatatc acttttcagt tacggaacaa
     1441 gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta atttatcata
     1501 gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct tttgtttttt
     1561 atcggagata cttatggata gataaataag ataggtttga aaagcgaaga gaataataaa
     1621 gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat aggctaaata
     1681 tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc ctagaagtct
     1741 cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg ctcctccgga
     1801 attacctcca taaacctcac tcagcattgt ttcatttata ttacaataag tattcataca
     1861 agtctccttt tattaaaatc cacccgttgc ccctgttact cctgcccaaa gatccacacc
     1921 aaatttagct cctatgtatc cacatgctcc cataaatggt gctccaacac cactcgcagc
     1981 acaaatagct gtccctagcc cccagccacc aaaagcagca ccaccacctt ctaagacatt
     2041 agtttgccaa ttattcttgc ctccttcaat actagataac atagttatat ccatttcatg
     2101 aaattgttcc ataatttttg tatccatgac aaatactctt ttttattttt aatttttgtc
     2161 ttgttgtaac tttgacaagt ttagtatatc atcgtttttt aaaatttttc atccagatct
     2221 tgaatagtca tcgaaacgtc ttgaattgca aaaattacat tagacttcct gcaaaactag
     2281 aatcctagtt catgattgat aataccaaca ctcaaattca ttcgtaatcc gaagcgttta
     2341 cgatgatttc gataggttgt tgcaaacatt ttaaacgttt ttactttggc aaagatgttc
     2401 tcaaccttgc ttctctcctt agatagcgca tggttacagg ctttatcttc aactgttagc
     2461 ggtttgagtt tgctggattt acgtgaagtt tgtgcttgag gatatatctt catgagccct
     2521 tgataaccac tgtcagccaa gatttttcca gcttgtccga tatttctgcg actcattttg
     2581 aacaacttca tatcatgaca atagttcaca gtgatatcca aagaaacaat tctcccttga
     2641 cttgtgacaa tcgcttgagt cttcatagcg tgaaatttct ttttaccaga ataattcgct
     2701 aattcttttt ttagggcgat tgatttttac ctctgttgca tccacaatca ccgtatcctc
     2761 agcactaaga tgagtttttg aaatcgtaac accactttga acaagagtta cttcaaccca
     2821 ttggctccga cggattaagt tgctttcgtg aataccaaga tcagccgcaa tttcttcata
     2881 agtgcggttc tcacacatat tgaa
//
LOCUS       DAVMBH010000087         2714 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVMBH010000087 DAVMBH010000000
VERSION     DAVMBH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.087"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(350..646)
                     /locus_tag="VYP30_002055"
     CDS             complement(350..646)
                     /locus_tag="VYP30_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEV1808972.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            complement(1177..2070)
                     /locus_tag="VYP30_002056"
     CDS             complement(1177..2070)
                     /locus_tag="VYP30_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808973.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
BASE COUNT          955 a          510 c          304 g          945 t
ORIGIN      
        1 atccaataat atctagaaaa tacaaaataa ataaataaat gaatgattgt aaaatttgga
       61 aagaataata tttcttgaca atggcaagaa gatagagaaa aatatagttt ttccttatat
      121 agaaagtatt tattttttta ctttggatag gcagtttcat attataacga ttcaaagtag
      181 cgtaatctac taccaaaaaa agtaaaaata atttcccttg aaaaggaaga tagcttttaa
      241 aatagattga caaacttatg ataacaaaaa acaaaagggt tatcccaata aaattaagat
      301 aacctaaaat actttcacat tcttttttag aaagtatttt catctagttc taccatagag
      361 ctgctttagc agcacctttc tttttcaata tataaagaac tgttgctgca atacccgaac
      421 caatagaacc tactcctgtg attgcaccta caattgaaat tactgctgta actgtactat
      481 aagcactaat caaattgact acagtagcag cagcttttgt cgaaattcct aatgtcccag
      541 ccaacatagg aaaagaaaca acacctaagc ttaaccaact aatgactgct aacattgctg
      601 aaacaataag aaatttatta tgaaattcca ttcttttaga tttcatttta gtgtactcct
      661 tttgtatatt atgtatgttt tattgagagt taattcgcac atgttgtatt cctaactctc
      721 ttcaaatgtt cgtctatatt ttatactact tttattaaca tatctataat aaataaatta
      781 ctactacatt ttcctagatt atcaaattac ttttatatca ctaagactca ataaaagata
      841 atgtctattt aacttttata cgattactac cttcttttta gtttacactt cctacatcat
      901 aaataaacat actcaaccct cacaatctcc aaataactct tctatatcat tgaaaattga
      961 gtttcatcct ctatactaat gtaggacatt cctttaatcc aatataagaa taccttgttc
     1021 cattaatctc tacccgatat tatagataga accaaattcc tatacttaaa aggacaaata
     1081 acgttccaac cataataaac ctcctttctt tttgagaacg ttttctttat aggtttagta
     1141 tagcaaaaac atgaaaaaaa caacatgact tagaagtcag gttgttggga aatctatctg
     1201 tttttctgct aaaattctct gaactaatac ctgatcgtct agcaattctg ctagagaaat
     1261 cgccttttca tagaaacttt ctgcctctaa aatattcttg tctacaaata aagcatattt
     1321 tgcctttagc aaaaatagat gaggtcggta aaaaacatgt cttgttttag caataatttt
     1381 ctcaaatgtt tgaatatata tcagactatc ttctgtctga atttggataa ataggctcag
     1441 aagaactttt tccatttgaa ctaggctagc cttatcttca tattctgaac atagcaatac
     1501 tttttgagct aactcctcaa aatgttcttt atcttctaat cccatagcac aacaaaagaa
     1561 atacaattca ataatcaaca aatcatttac agaaaaatat ttctttttta ataactgctg
     1621 gaaatattct tccactaacc ctaaaccgta ggtcacatct gaactaccat aaatatcaaa
     1681 acgagcttgt gtcacatcca caattaactg ctcttcctca ggcaaattct cataatagtt
     1741 ttcatatatt tcctcaagta tagcttcttt tcgttcgatt cttcccttat cagcgtaggt
     1801 ttgagaatga atcagctcat ctttgagttt taggaatcct tttggaatct ctataacctt
     1861 aacatccaca atattctgta atgatactcc aagtttatcc gcaatcaata ataatttagg
     1921 aagtgttgct aaagcttgcc cattttcaat acgtgctagc tgacgaatcg tcaactctga
     1981 ttcatcacca caaatatcta tctgagtttt tccacaagat cgcctaatag ttttgatttt
     2041 ataaccaatt tcacgtttca actcatccat agtaatactc cttaagttga ttacaaagat
     2101 ttctttttct tcctaattct tttgtcaatc atatataaaa cgataagcga aaacagcggt
     2161 agaacaatat aactcttttc actcattatc agctgaaatc ccagggttgc tagtatctta
     2221 aagatgaaaa tattcatcaa aaatagaaaa acaaatacta aaaaatattt taaaaccttc
     2281 ttcatttctt ttcttcaact ttcctaattt ctacacctat tttatcgaaa atatatataa
     2341 aactccaaat aaacacttcg actgcacttt ttttggcaaa aaatagacag aacaaacatc
     2401 ctacctacta aaaatatgat atgaaaggaa aatgattttt tactgacacc ctaggcaagc
     2461 ttgggacaaa taaatcattg atagcaacat ttacgacatc ctatttaaag ttccttcaat
     2521 ttctaatgtc cccgctattt ctaagccacc tctggtatga tctattccta gtcagaatag
     2581 ataacaccgt tctaaatcac gattcatagt tactcctttt ttgactcgtt actataagac
     2641 tcctctttac atgcgcaaaa taattttgat tcagattcat catttatagt tttgattatt
     2701 ttttaacaga tttt
//
LOCUS       DAVMBH010000088         2317 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVMBH010000088 DAVMBH010000000
VERSION     DAVMBH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.088"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(49..999)
                     /locus_tag="VYP30_002057"
                     /pseudo
     CDS             complement(49..999)
                     /locus_tag="VYP30_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1076..1531
                     /locus_tag="VYP30_002058"
     CDS             1076..1531
                     /locus_tag="VYP30_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1808974.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYSNPAYFY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            1696..1995
                     /locus_tag="VYP30_002059"
     CDS             1696..1995
                     /locus_tag="VYP30_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1808975.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          752 a          437 c          398 g          730 t
ORIGIN      
        1 tttactttcc caatcgattt gttctcatct tatttcaatc tgctatagtc aattgaaaca
       61 agaacaggac aaaagagcct cgtaaaaggt attgcaactt ggtaatacct ttttgaggtg
      121 ctttttgata tgagcccatg ttttctcaat aggattgtac tcaggcgagt agggaggaag
      181 aggtaaaagt ttatgcccaa actcttcgca taaaagttct agcttcccca ttctatggaa
      241 tcttgcatta tccataatat agtagattga aactagaata gtacacatct acttctaaaa
      301 cattgttaga attcgatttt actatcctga tcgatttatc ctattcttat tttattttac
      361 tataataacc gatggtgtgg ttaatgttgg taagagaaac ttctgaaacc aagcttcaaa
      421 aaagtcgctc gtcatcgtct cttcgtaagt cattggagcg attaattcac catttgttag
      481 acctgcaacc aaagaaatcc tctgatatct tcttccagat actttgcctc ttattaactg
      541 accttttaat gagcgaccat attctcgata aaaataagta tcgaatcctg tttcgtcaat
      601 ctaaacaggt gctaggtgct ttaaactatt aaaattctta agaaataagg ctactttttc
      661 tgggtcttgt tcatagtagg tgtggttctt ttttcgagtg tagcccatag ctttgagcgc
      721 atagtggatg gtagttggat gacagccaaa ttcagaagct atttcagtca aataagcgtc
      781 tggattgtca gtaagatagt ttttaagtct atctctatca acttttcttg gttttgttcc
      841 ttttacttgg tggtttagct ctcctgtttt ctcttttagc tttaaccagc cataaatggt
      901 attacgtgag atttggaaaa cgtgtgatgc ttctgttata ctacctattc gctcacaata
      961 agagagaact tttttacgaa aatctattga atatgccata agaagattat accacattgt
     1021 gtactatttt tggttcattt cactataata ataacgatac tagataatga ggaaaatgca
     1081 atggcaaacc caactttcgg agaaaaaagc gaatacagac tatattgctc gctatggcgt
     1141 atatgcagtt atccctaatc ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg
     1201 tgcttggttc ctaccatgtg gagaaattga agcaggtgaa aatcatcagg aagccctaaa
     1261 gcgtgagttg attgaagagc ttggtttcac agcagaaatt ggtacctatt acggacaagc
     1321 tgacgaatat ttctattctc gtcatcgtga tacctactac tccaatcctg cctacttcta
     1381 tgaagcaact cctttcaaag aagtacaaaa gccactagaa aactttaatc atattgcctg
     1441 gttccctatt gacgaggcta tcaaaaacct taaacgtggt agccataaat gggccattga
     1501 atcttggaaa aaacagcata agattgacta atactcttcg aaaataaaat tcaaaccaca
     1561 tcagcgtcgc cttaccatac tcaagtatag cctgcggcta gcttcctagt ttgctctttt
     1621 attttcattg agtataaatc aagcgacttt attcaaaaag tgctataata gaattagaaa
     1681 accggaggaa atattatgaa gcttatcaat acgacaaact cacactcgca acttgtaaaa
     1741 agtcagctag aaagtaccga tgcaaccctt gttgaggttt attctgcagg gaatacagat
     1801 gttattttta cccaagctcc gcttcactat gaaatcctca tctcaaacaa acaccgtgct
     1861 attcgtgagc ctgaaatcga aaccattcaa gaatttttct tgaaacgtaa aattgataag
     1921 acctctgttg atgaagccaa tatcaagaca ctctactcag agaaattaat tggaatttca
     1981 atcccaatca agtaagaaaa ttgagtaaaa actcgatttg agagaaagtc caataagtct
     2041 ttccataaca aaacgcatag taacaagagt ttctacaccc actattatgc gtttttatca
     2101 ttttgaaatc tactgcaatc aatgaagaag caaagatcaa actaggcagc tagttacaag
     2161 ttacgtaagc gcgtcataac aaggtatcta tcctaattcc ccaacttcca gtatactaga
     2221 taaaaaataa ttatcggagg aaaggtattg tactatgata attcaactaa gtgatttagg
     2281 tcaagttcac cttgtttgtg gtaagacaga tatgagg
//
LOCUS       DAVMBH010000089         2183 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVMBH010000089 DAVMBH010000000
VERSION     DAVMBH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.089"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            30..1901
                     /gene="lanM"
                     /locus_tag="VYP30_002060"
     CDS             30..1901
                     /gene="lanM"
                     /locus_tag="VYP30_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV1808976.1"
                     /translation="MLEKQFYSEIYYLTIRTLIDDFYNWQRVNESVPKEERYHRYCLK
                     LGTVPFFKKIKKAYPVLFIKIFHLHQHTINLIEEAMLSIIRDKDEIKERIGFNFDDGI
                     KEIVLSTGDRHNGGKTAVIFKNNNDDKILYKPHSLNNDVFLENFFSLVNRSLPLKLYH
                     PKSISKKNYGWQEFIEFQECNLDNDYEDYFYRYGELLAIAYALQVTDLHKENIIMSKN
                     YPIVIDSETLFTNPDLSCNRNSTIQNPETVHDLFQKFIKDSVLDTLLLPNNFQSSLFD
                     FDLSPLTNYQQLSENITRFTIENDFSHNIHLKEVHVVLPSSNVKKETNKFYGKIIDGF
                     KACYTILENSKNYFIEEIKLLSEKYPLYLRQVLRPTMVYVKFLEASTHPDYLTDIKKQ
                     RKLFQKLNSSLYKLDSTLGKQVEIEINSLMKGDVPYFYTKFNSLSIYSMENKICNFYA
                     TSIQSKLLERFQKLGNKDMLKQLHVIFLSLSTVKDTTFSDINQSPLHDFIIPVNDENS
                     LVLKVGDYVNHQVVWNNNNEFCILPSVTQIDDKKVILPVSYCLYDGGGVVLLLYYLYL
                     KFNEEKYKIVADGLLKGFESMIEIETNRNFSAFNGIGSVIYIYILLPFYTNIGTRLS"
     gene            1855..>2183
                     /locus_tag="VYP30_002061"
     CDS             1855..>2183
                     /locus_tag="VYP30_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV1808977.1"
                     /translation="MYYCLFILTSEPDYHEKYKFYLAMLEKQDIPLDQPIDFLGISSL
                     IILLCNIYKIEHSSKLFTLLKKCINYCISQLDNITVTGLAHGYSGVAMSLSYYYEINP
                     STDILKC"
BASE COUNT          822 a          264 c          332 g          765 t
ORIGIN      
        1 gacgttatct ttcagaagga tctatagaga tgctagaaaa acaattttat tctgagatat
       61 attatttgac aattcgtact ttgattgatg atttttacaa ttggcaaaga gttaatgaga
      121 gtgtaccgaa agaagaaaga tatcatagat actgtttaaa attagggacg gttccttttt
      181 ttaaaaaaat taagaaagca tacccagtct tatttattaa aatttttcat ttgcatcaac
      241 atacgattaa tttaatagaa gaagcaatgt tatcaatcat tagagataaa gatgaaatta
      301 aggagcgtat aggattcaat tttgatgatg gaatcaaaga aattgtactt tctactggtg
      361 ataggcataa cgggggaaag actgcagtta tatttaaaaa taataatgat gataaaattt
      421 tatataagcc tcattcatta aataatgacg tatttttgga gaattttttt agtttagtta
      481 atagaagttt acctttaaaa ttataccatc ctaaatcaat ttcaaaaaaa aattatggat
      541 ggcaggagtt tatagagttt caagaatgta atcttgataa tgattacgaa gattactttt
      601 atagatatgg tgaacttctt gcaatagctt atgcactgca agtgacagat ctccataaag
      661 aaaacataat aatgagtaag aattatccga ttgttattga ttctgagact ttatttacaa
      721 atccagactt aagctgcaac aggaattcaa ctattcaaaa ccctgaaact gtacatgatt
      781 tatttcaaaa gtttatcaaa gactcagttt tagacacatt attgttacca aataattttc
      841 aaagctcttt atttgatttt gatttaagtc cgctgactaa ttatcaacaa ttatctgaaa
      901 atattactag atttacaata gaaaatgatt tttcacataa tattcattta aaagaagtac
      961 atgtagtact tccgagtagt aatgtcaaaa aagaaactaa taaattttat ggtaagataa
     1021 ttgatggatt caaagcttgt tatactatac ttgaaaatag taagaattat tttattgaag
     1081 aaataaaatt attgtcagaa aaatatcctc tatatctgag acaggttcta agaccaacta
     1141 tggtatatgt taagttttta gaagcttcaa cccacccaga ttaccttacg gatatcaaaa
     1201 aacagagaaa gctatttcaa aaacttaata gctcgttata taaattagac agtactttag
     1261 gcaagcaagt agaaattgaa attaatagtt taatgaaagg agatgtaccg tacttttata
     1321 caaaatttaa tagtctgagt atttattcta tggaaaataa aatttgtaat ttttatgcta
     1381 catctatcca aagtaaacta cttgaaagat ttcaaaaact gggaaataag gatatgttaa
     1441 agcagttgca tgtgattttt ttatctttat cgacagttaa agatacgact ttctctgaca
     1501 taaatcaaag cccattacac gattttatta ttcctgttaa tgacgaaaat tctctagtat
     1561 taaaggtcgg cgactatgtt aatcatcaag tcgtttggaa taataataat gagttttgca
     1621 tacttccttc tgttactcag attgatgata agaaagttat tttaccagtt tcttattgcc
     1681 tgtatgatgg tggtggagta gttttactat tatattatct atatttaaaa ttcaacgaag
     1741 aaaagtataa gatagttgcg gatggtttac taaaggggtt cgagtcaatg attgaaattg
     1801 aaacaaatag aaacttttcg gcgtttaatg gcattggatc agtaatatat atatatatat
     1861 tattgccttt ttatactaac atcggaacca gactatcatg aaaaatataa gttttactta
     1921 gcaatgctag aaaaacaaga tattccgtta gatcaaccaa ttgatttttt aggaatatcc
     1981 agtttaatta ttttattgtg taatatttat aagatagaac atagctcaaa actttttaca
     2041 ctattaaaaa agtgtattaa ttattgtatt tcacaattag ataatataac agtaacaggt
     2101 ttagcacacg gttattctgg agtagcaatg tcattatcat attattatga aattaatcct
     2161 agtacagata tattaaaatg tat
//
LOCUS       DAVMBH010000090         1845 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVMBH010000090 DAVMBH010000000
VERSION     DAVMBH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1845
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.090"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..282
                     /locus_tag="VYP30_002062"
     CDS             <1..282
                     /locus_tag="VYP30_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808978.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(416..503)
                     /locus_tag="VYP30_002063"
     tRNA            complement(416..503)
                     /locus_tag="VYP30_002063"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(467..469),aa:Ser,seq:gct)
     gene            complement(510..583)
                     /locus_tag="VYP30_002064"
     tRNA            complement(510..583)
                     /locus_tag="VYP30_002064"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(547..549),aa:Ile,seq:gat)
     gene            complement(619..689)
                     /locus_tag="VYP30_002065"
     tRNA            complement(619..689)
                     /locus_tag="VYP30_002065"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(655..657),aa:Gly,seq:tcc)
     gene            complement(709..781)
                     /locus_tag="VYP30_002066"
     tRNA            complement(709..781)
                     /locus_tag="VYP30_002066"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(746..748),aa:Phe,seq:gaa)
     gene            complement(785..858)
                     /locus_tag="VYP30_002067"
     tRNA            complement(785..858)
                     /locus_tag="VYP30_002067"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(822..824),aa:Met,seq:cat)
     gene            complement(872..961)
                     /locus_tag="VYP30_002068"
     tRNA            complement(872..961)
                     /locus_tag="VYP30_002068"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(923..925),aa:Ser,seq:tga)
     gene            complement(972..1045)
                     /locus_tag="VYP30_002069"
     tRNA            complement(972..1045)
                     /locus_tag="VYP30_002069"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1009..1011),aa:Ile,seq:cat)
     gene            complement(1059..1132)
                     /locus_tag="VYP30_002070"
     tRNA            complement(1059..1132)
                     /locus_tag="VYP30_002070"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1096..1098),aa:Met,seq:cat)
     gene            complement(1138..1211)
                     /locus_tag="VYP30_002071"
     tRNA            complement(1138..1211)
                     /locus_tag="VYP30_002071"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1175..1177),aa:Pro,seq:tgg)
     gene            complement(1227..1300)
                     /locus_tag="VYP30_002072"
     tRNA            complement(1227..1300)
                     /locus_tag="VYP30_002072"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1264..1266),aa:Arg,seq:acg)
     gene            complement(1310..1395)
                     /locus_tag="VYP30_002073"
     tRNA            complement(1310..1395)
                     /locus_tag="VYP30_002073"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1359..1361),aa:Leu,seq:taa)
     gene            complement(1403..1474)
                     /locus_tag="VYP30_002074"
     tRNA            complement(1403..1474)
                     /locus_tag="VYP30_002074"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1440..1442),aa:Gly,seq:gcc)
     gene            complement(1497..1569)
                     /locus_tag="VYP30_002075"
     tRNA            complement(1497..1569)
                     /locus_tag="VYP30_002075"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1534..1536),aa:Thr,seq:tgt)
     gene            complement(1588..1669)
                     /locus_tag="VYP30_002076"
     tRNA            complement(1588..1669)
                     /locus_tag="VYP30_002076"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1633..1635),aa:Leu,seq:tag)
     gene            complement(1675..1747)
                     /locus_tag="VYP30_002077"
     tRNA            complement(1675..1747)
                     /locus_tag="VYP30_002077"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1712..1714),aa:Lys,seq:ttt)
     gene            complement(1772..1844)
                     /locus_tag="VYP30_002078"
     tRNA            complement(1772..1844)
                     /locus_tag="VYP30_002078"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1809..1811),aa:Asp,seq:gtc)
BASE COUNT          538 a          490 c          379 g          438 t
ORIGIN      
        1 aaggaaccag agaaattttt cggacttatt gaggacaatc ttaagcaggt tcatcctatt
       61 tttcagactg tctttaaaac cttcctcaaa gataaagaaa agattgtcaa cgcccttcaa
      121 ctacactatt ctaacgccaa actggaagcg accaataatc tcatcaaact tatcaagtgc
      181 aatgcctttg gttttcgaaa ctttgaaaac tttaaaaaac ggatttttat cgctttgaac
      241 atcaaaaaag aaaggacgaa atttgtcctt tctcgagctt agcttttctt caacccacta
      301 cagttgacaa agagccataa aaataacttc agattagtaa ttcaattaag ttttacggat
      361 ctgaagcttt attgtctcta aaaataaaaa agagagttac aaactctcat taaaacggag
      421 aataagggat tcgaaccctt gcgccagtta cccgacctaa cgatttagca aaccgtcctc
      481 ttcagcctct tgagtaattc tccaattaat gggcacgagt ggactcgaac caccgacctc
      541 acgcttatca ggcgtgcgct ctaaccacct gagctacgcg cccaagttaa aaaacttggt
      601 aatttgaaca aagttcaaag cgggtgacga gaatcgaact cgcgacaaca gcttggaagg
      661 ctgtagtttt accactaaac tacacccgca taaatactat caataaaatg gcgcgagacg
      721 gaatcgaacc gccgacacat ggagcttcaa tccattgctc taccaactga gctaccgagc
      781 cttattgcgg gagcaggatt tgaacctacg accttcgggt tatgagcccg acgagctacc
      841 gagctgctcc atcccgcgtt aataatataa aaggaggatg tgggattcga acccacgcac
      901 gcttttacac gcctgacggt tttcaagacc gttcccttca gccggacttg ggtaatcctc
      961 caatattcaa atggaccttg taggacttga acctacgacc actcggttat gagccgagag
     1021 ctctaaccag ctgagctaaa ggtccgacaa gatcattata gcggcgaagg ggatcgaacc
     1081 cccgacctcc cgggtatgaa ccggacgctc tagccagctg agctacaccg ccatgaatcg
     1141 ggaagacagg attcgaacct gcgacacctt ggtcccaaac caagtactct accaagctga
     1201 gctacttccc gagttaaata gaaaaatgca ccctagagga gtcgaacctc taaccgcctg
     1261 attcgtagtc aggtactcta tccagttgag ctaagggtgc tccatattat gccgaggacc
     1321 ggaatcgaac cggtacgatc gttaccaatc gcaggatttt aagtcctgtg cgtctgccag
     1381 ttccgccacc ccggcctctc taagcgaacg acgggattcg aacccgcgac ccccaccttg
     1441 gcaaggtggt gttctaccac tgaactacgt tcgcactgtt ttcttctatc taaaaatgcc
     1501 ggctacatga cttgaacacg cgaccctctg attacaaatc agatgctcta ccaactgagc
     1561 taagccggct catttgttat atcttaatgc gggttaaggg acttgaaccc ccacgccgtt
     1621 aagcgccaga tcctaaatct ggtgcgtctg ccaattccgc caaacccgca tatatgaccc
     1681 gtactgggct cgaaccagtg acccattgat taaaagtcaa ttgctctacc aactgagcta
     1741 acgagtctaa aataacttgc gttaccttaa acggtcccga cgggaatcga acccgcgatc
     1801 ttcgccgtga cagggcgacg tgataaccgc tacactacgg gacct
//
LOCUS       DAVMBH010000091         1780 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVMBH010000091 DAVMBH010000000
VERSION     DAVMBH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.091"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            360..836
                     /locus_tag="VYP30_002079"
     CDS             360..836
                     /locus_tag="VYP30_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1808979.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            836..1597
                     /locus_tag="VYP30_002080"
     CDS             836..1597
                     /locus_tag="VYP30_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PezT"
                     /protein_id="HEV1808980.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          652 a          236 c          348 g          544 t
ORIGIN      
        1 aaacaacact ttattgaggt attggatacg ctttgctaat agcctaataa tcacatgtgg
       61 agtgttgcta caacgaaaaa ggtgataatc cttgatttca agctatttta taagcatttt
      121 gtctttgtag ataaaggcaa ttttgacaat aaaaatccta aaaggtgaat cgttatagat
      181 gtatttgtag atatcgtttg cgcatcgaaa aaattaatac aagaataaat atttatggct
      241 ctttaggtga cttttataga agtaaagttt aggatagaaa aacaagaaat aacgcaccat
      301 ttttggtgcg ttatgctttt ttatgctata atggatttat aaaaataaag gagtttgcta
      361 tgattggaaa gaacataaaa tccttacgta aaacacatga cttaacacaa cctgaatttg
      421 cacgaattat aggaatttct cgaaatagct tgagtcgtta tgaaaatgga actagttcag
      481 tctctacgga attaattgac atcatttgtc agaagtttaa tgtatcttat gtcgatattg
      541 taggagaaga taaaatgctc aatcctgttg aagattatga attgactttg aaaattgaaa
      601 ttgtgaaaga aagaggtgct aatctattat ctcgactcta tcgttatcaa gatagtcagg
      661 gaattagcat tgatgatgaa tctaatcctt ggattttaat gagtgatgat ctatctgact
      721 tgattcagac aaatatctat ttagtagaaa attttgatga aatagagaga tatagcggct
      781 atttggatgg aattgaacgt atgttagaga tatctgaaaa gcggatggta gcttaatgga
      841 aatccaagat tatactgata gtgaattcaa acatgcttta gcaaggaatc ttcgttcact
      901 gacaagagga aaaaagtcca gtaaacaacc tatagcgatt ttgcttggag gtcaaagtgg
      961 tgccggtaag actacaattc atcgtattaa acagaaagaa tttcaaggaa atattgttat
     1021 catagatggt gatagttttc gttctcagca tccacactat ttagaactgc agcaagaata
     1081 tggcaaagac agtgtagaat ataccaaaga ttttgcagga aaaatggtag agtctttagt
     1141 aacaaaattg agtagtttga gatacaatct tttgatagag ggaactttac gaacagttga
     1201 tgttccaaag aaaacagcac aactcttgaa aaataaggga tatgaagtac aattggcctt
     1261 aattgcgaca aagcctgaat tgtcgtatct aagtactctt atccgttatg aagaactgta
     1321 cattatcaat ccaaatcaag cacgcgcaac tccaaaagaa catcatgatt tcattgtaaa
     1381 tcatctagtt gataatacac gacaattgga agaactggct atctttgaaa gaattcaaat
     1441 ttaccaacga gatagaagtt gtgtatatga ttcaaaagaa aatacaactt cagcagcaga
     1501 tgttcttcaa gagttactgt ttggggagtg gagtcaggta gagaaggaga tgttgcaggt
     1561 gggggaaaag agacttaatg aattacttga aaaataaaca attgatattt ttaggagagt
     1621 agaaatgaga gggtttaata acaagataaa gtctgtttat caagaactaa caaattccaa
     1681 agagaaattc ggtagctttc acaagacttt aattcatttg catacacctg tttcttatga
     1741 ttacaagcta ttttctaatt ggactgcaac gaaatataga
//
LOCUS       DAVMBH010000092         1773 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVMBH010000092 DAVMBH010000000
VERSION     DAVMBH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.092"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            55..1056
                     /locus_tag="VYP30_002081"
     CDS             55..1056
                     /locus_tag="VYP30_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1808981.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    1268..1497
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT          597 a          232 c          356 g          588 t
ORIGIN      
        1 aaaaaaatta aatattgtat agtaatatta gaatgtttgt aatagaggac tgaaatgaaa
       61 aatataaatg ggaaaaaggt aactatttat gatattgcac gtttatcagg tttttctcca
      121 aaaacagttt cacgagttat taatggtgga gtaaatgtta aagaagaaac ttatcaagcg
      181 attcaaaaag ttatagagga attgtcgtat attccaaatg cgtatgcaaa aaatttaact
      241 aaaaaagaag ctataaatat attgatttct gtaaaaaaaa tcgactcttt tcctttaatt
      301 tggtttcata cgctgttaga taaagtgtta cggacgtgta aagaatttgg tgttaatgct
      361 atagttgagt actttggaga ggaggataca attagtaatt caattatatc aagcacaggt
      421 agcctagtag atggtgttat tgttttttat gaaagtgtag atgatatcag aattcagtat
      481 ttaaagaaga accatatgcc ttttcttgtt ttcggtgaat ctcaaacgtc tggagtagtc
      541 tatgtatcta ataataattt tcaagctact tatgatatga tgaaagctgt aactgaagaa
      601 aaatttaaaa atatgtggtt gcttatggga ggagaatctc atgttaataa ggatcgtgaa
      661 agaggtgtgc gttcttttct gaatgataaa aattacttta tggatttaaa agtcatttat
      721 ggcttatcta caattgattc agtttattct tatgcaatgc agcacttgac tacccaaaat
      781 tatccggaca ttatttttgt ttcaggagat gaaaaggttc agggcttgat tcgtgcgtgc
      841 tatgagaaag gaattcttat tccagatgat atttctatta ttggatttga taatattcct
      901 atttctcagt attatactcc agctttgtct acaattgctc ccaattatgt taaattggct
      961 aaagaaatga tagaaggtgt tttagcaatt attaaagggg aaagtgtcac atctgttgaa
     1021 gtttctccta aatttgttag gagacagagt ttctagtatt gtttaattct tgaaaatcct
     1081 agtggaaaag atggagtgtt ctaaaataag ttctgtttag cctccattca gtttctattg
     1141 agttggatcc aatttctaac aagtgggaca tgttcatgtt cgatctaagg aagacatggt
     1201 cacattcgaa tgatattttc aaaaaaatcg taaaaaagtc ttgacaaaga aaaaacaaag
     1261 tattaaaata agttcaacaa atcagaaaag taactatttt tgatcttcag ggagcctgtg
     1321 gtggttgtga ataggtggtt ggaagtagtg aaagtgggct gattttgaaa atgaatttga
     1381 aacaatgaaa attcggtgcg cacaccttac agtgcagctt gttgttaaac aaggcagaga
     1441 tgtaaaggga tagtcccttt ataattgagg tggcaccgcg ttaccaacgc cctcacacgg
     1501 aagtatattc tgtgtgtggg cttttttcta tccgtcgttt ggtttatctt ttattagggc
     1561 cttaagtcgc tttgatgaac ttgagttcta tctacagctc cttgcctact actaaaagca
     1621 aacaaaaagg ctggactaat acgaaaaaag ctagtaatac tcaatgaaaa tcaaagagca
     1681 aactaagaaa ctagccgcag gttgctcaaa acactgtttt gaggttgtgg atagaactga
     1741 cgaagtcagc tcaaaatact gttttgaggt tgt
//
LOCUS       DAVMBH010000093         1752 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVMBH010000093 DAVMBH010000000
VERSION     DAVMBH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.093"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(19..615)
                     /locus_tag="VYP30_002082"
     CDS             complement(19..615)
                     /locus_tag="VYP30_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1808982.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEISNK"
     gene            complement(612..1094)
                     /locus_tag="VYP30_002083"
     CDS             complement(612..1094)
                     /locus_tag="VYP30_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEV1808983.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKDRGIKNILIYIKSNLKWYIISYLLLILAALIEGIKL
                     "
BASE COUNT          689 a          282 c          202 g          579 t
ORIGIN      
        1 attaatttgt ataaactatt atttgtttga aatttcataa acccgtcctt cctctattaa
       61 aatcctttga gatttgctaa tcaattcttg attcaataaa ttatgagata catatataat
      121 agtagagctt tctttcatgg aaattaagcg tttagcaatc atatcaatac ttcttgcatc
      181 cactgttgat aaagtctcat caataaaaat ataatcccaa tttttagcaa aaattaagga
      241 taagcctaat ttgaattttg ttccagtaga tgctgtcata tagttatctc cgattttatt
      301 atcaaaaaaa gtattaattt gttctttatc ctcaaatgat agatggattt gaaaagaatc
      361 acacaacaac tgcaaatttt cttctatagt aaatggaaca accccaagct gattggtatc
      421 aaggtatagt acatctttgg agacacaatt ctttaaacca ctatcaaaag tctctagccc
      481 agctaaaagt tgtagaaggg tgctctttcc tgaaccattc tctccttcaa ctctgtaaat
      541 tcccttatca atctctagtg atatattttt caatatacat ttatcataac ttttagattc
      601 attttcaatt ttcataattt aattccctct atcaacgctg ctaaaattaa taaaagataa
      661 gaaatgatat accattttaa attacttttt atataaataa gtatattttt aattccccta
      721 tccttcaata atcggtataa aagatactga ctcatacctt gataccaaat aaaattcggt
      781 atttcaataa gagcatgagg taatattcct tttattgtag ctactattcc aatcatctga
      841 ccagatatac ccaattgtat tcctaaagat agcaaatcaa aaagttgcaa taagggcgaa
      901 atcggaaaac agaatagata tagcaaaaaa tttgtagaat ttgcctgtaa aactgtcaat
      961 gtaaattgta attccagttt cggaggtata gtagcaaaag tctcattttt taatataaag
     1021 cttaaaagta aacctagtaa aaaacagact atacaaaata acacatagta aatcagaaaa
     1081 ccactttttc tcatctaatg ccccctacta aaattacaaa tattatcaga aaacaatata
     1141 aaaccagaaa actccatctc aataaactaa ctgtaccttt aattaaaaat agagctttct
     1201 tataatagac ataggctata aaataattga atggaatcaa taacaaattc aacaaaatac
     1261 tttttatatc attactataa cttgtcaccg gaatcaaaca taacaacaat gaaaattgta
     1321 agaaagagat taaatgcgtc aacatcatta gttgtgcatt cttaaaaaag aaattcattt
     1381 tagaatgatt aagagcagat aattgaagta aagctagatc taccccaatt gaggatttat
     1441 gattccctat tattgcctcc attaatgtaa tatatattga ggtataaaga aataatattg
     1501 gtatttttgt gtcatcaatt gataacatcg tcatcatata ccaaaataga taggaaagaa
     1561 gaatactaat caaaataaaa gaaaaagtta accctttatt taaccaacaa aaacgaagca
     1621 atataaatag actgctacga aatctttttt gactcattcg actgctttta aaatagaaat
     1681 tactcgcatg attatctaat atccccatga ctaaaataaa ataattgagt agtatgacat
     1741 aaattacaac tt
//
LOCUS       DAVMBH010000094         1541 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVMBH010000094 DAVMBH010000000
VERSION     DAVMBH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.094"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            63..788
                     /locus_tag="VYP30_002084"
     CDS             63..788
                     /locus_tag="VYP30_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV1808984.1"
                     /translation="MDQILVERKRDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIP
                     FLNPKAKERVGYPTQKPILLLEQIIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMG
                     IDLSEEAINITQQRLENVIKTSSNLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGI
                     DGFLPKHFQKKPIPIKIQKNNECLNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFD
                     TIPENIIVVDHFELTIEKWLSKS"
     gene            825..1500
                     /locus_tag="VYP30_002085"
                     /pseudo
     CDS             825..1500
                     /locus_tag="VYP30_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921814.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          574 a          234 c          278 g          455 t
ORIGIN      
        1 attcaaagtc aaaagatttt aaatttaata caatttttac agagtattct tctactacaa
       61 atatcgacca aatactagtg gaacgaaaac gagatggaaa ctctaaaact atatataaag
      121 ttgataataa tggtaactat attctagcaa aagagaaaaa tggagttccc ctttcagatg
      181 tttggaatat accatttctt aatccaaaag ctaaagaaag agtaggttat cctacacaaa
      241 aacctattct gttattagaa caaattataa agattgctac tgataaaaat gatatagttt
      301 tagacccgtt ctgtggaagt ggaactactt tagtagcctc caagattttg aatagaaatt
      361 atatggggat tgatttatct gaggaagcta tcaatataac tcagcaacgt ctggaaaatg
      421 ttataaaaac aagttcaaat ttattgaata aaggaatcga agcatataga accaaaactg
      481 aggaagagga aaacattctt aaattattac aggcaaaaat tgttcaaaga aataaaggaa
      541 ttgatggttt tttacctaaa cattttcaaa aaaaaccgat acctataaaa attcaaaaaa
      601 ataatgaatg tctgaatgag agtatctctt tattacagaa tgctataaac tccaaaaaac
      661 ttgattttgg agtagttata aaaactcatt cagataattt attatttgat tttgatacga
      721 ttcctgaaaa tataatagta gttgaccatt ttgaacttac aatcgaaaaa tggttaagta
      781 aaagttaaca gttactatag tttgcaaatt atttacagaa agaacaagaa ttcctaggag
      841 attattctgg ctatgtgcat tgtgatatgt tgcggcagta acttaggact ttagtcctct
      901 agttctgcct atgcgatagc agtccaaggt ttaggagcaa ggcgacgcta agcttggtaa
      961 actacgaacc gcagcaagcg gataaatcat ccttaggagc taaaggttta gcttattgtg
     1021 atcagttatt tgccttggaa agagactggg aggacattgt cagctgatga acgactacag
     1081 aaacgtcaag aagagctcca acccctaatg gaagacttct ttgcttggtg ccgtcgtcag
     1141 tcagttttag caggttcaaa actaggaagg gcaattgaat acagcctcaa gtataaagaa
     1201 acctttaaga ctattttaaa agacggacat ctggtccttt ccaataatct agctgaacgc
     1261 gccattaaat cattggttat gggacgtaaa aattggttgt tttctcaaag ttttgaagga
     1321 gctaaagcaa gagctattat tatgaactta ttggaaacag ctaaacgtca tcaactaaat
     1381 agtgagaaat atctatccta tcttctagaa tgtcttccaa acgaggaaac tctcgtaaac
     1441 aaagaggttt tagaggctta tttaccatgg actaaagttg tacaagaaaa gtgcaaataa
     1501 gaaatctcca gattaggaac tatccgtgag ttctctagtc t
//
LOCUS       DAVMBH010000095         1474 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVMBH010000095 DAVMBH010000000
VERSION     DAVMBH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.095"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            396..>1474
                     /locus_tag="VYP30_002086"
     CDS             396..>1474
                     /locus_tag="VYP30_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEV1808985.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSEKIHKYNSDVQVVPISI
                     KVSSLEELEKIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFGCRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNADVYNMRNHALSQKKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFIGMIIFLML"
BASE COUNT          519 a          165 c          258 g          532 t
ORIGIN      
        1 aattctaaca ataataactt gaattttcaa tatatagttc aacttttaat agcatttgtt
       61 attatttatt tccctttgag tcaactatta cagtttttga cacctaatat tattgttcgt
      121 agtataggag gggtggttgt ttctatactg ctttctatat tatatatgag aggaaggacg
      181 aaatatgttc tacgtaaata gttatgtttt tgcttataaa aaagaaggta taatgtattt
      241 gcgtggtcgg agtatgcggg aaatagctat agaacctcaa atttcgcaag aatttatcaa
      301 cgatcaagga actattagag atagaagaag tattaggcag taaactaaca tttgaactat
      361 taaatgaaca aattttaatt tcggatgaga tagatattga tagtagatat tctagaacta
      421 aaggttacta ttcgttattt tataatgaag agtataataa aatacagaat aaaacagtat
      481 tagtattagg agcaggagcc ttaggatgtt atatatcttt aagtctaagt atgtatggag
      541 tgaggaaact tattgtcgct gattacgata taatagaacc atcaaattta aataggcaaa
      601 ttctttatac agagtcggat gttggtaagg agaagattaa tgttctttct gaaaaaatac
      661 acaagtataa ttcagatgtt caggtagtac ctatttctat taaagtttct tcattagaag
      721 aattagaaaa aattgttgcg gaatatggga gtatagattt tatcgttaaa gcaattgata
      781 cgcccattga tattataaaa attgtcaatc aatttgctgt atcgcataag atatcctaca
      841 tatcaggagg gtttaatgga tgctatctta ttattgataa tatatatatc cctaccatcg
      901 gttcttgctt tggttgtcgg aatataaaca aagatataaa taagtacact ttatctgata
      961 agacaaagtg gccgactaca ccagagatgc ctgctatttt gggagggata atgactaatt
     1021 taataattaa aatatttctg ggatgttata atgaaatcct aatagataac gctgacgttt
     1081 ataatatgag aaatcatgct ctaagtcaaa aaaaatatgt tctggaaaac ggagaatgtc
     1141 caatttgtaa aaaaaataat aaagtgaaag ataacaatat tagagcgaaa acatttattc
     1201 gttcagtttg tttttgctta ttatcaggag gagtagcttt tttatctgct attgggcagt
     1261 tcactgttat agaaacacaa ttaatagtat tgttcttggg tattattttt gctatatatt
     1321 atgcttacta caataaaaat attcaaacat cattggaaaa tatagtatgg cttttttcat
     1381 cgtttgagat tttatttttg cttgttaatt ttagaacatt tattcagtta ccagtggata
     1441 tttttattgg tatgataata tttttaatgc tgtg
//
LOCUS       DAVMBH010000096         1459 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVMBH010000096 DAVMBH010000000
VERSION     DAVMBH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.096"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            73..>1459
                     /gene="pcpA"
                     /locus_tag="VYP30_002087"
     CDS             73..>1459
                     /gene="pcpA"
                     /locus_tag="VYP30_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1808986.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     YIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGV"
BASE COUNT          576 a          201 c          229 g          453 t
ORIGIN      
        1 actttttata acaacggcta gcaaagttat aattttatat ctattagaaa ataaatatgt
       61 aaggaaattt aaatgaaaaa aactacaata ttatcattaa ctacagctgc ggttatttta
      121 gcagcatatg tccctaatga accaatccta gcagatactc ctagttcgga agtaatcaaa
      181 gagactaaag ttggaagtat tattcaacaa aataatatca aatataaggt tctaactgta
      241 gaaggtaaca taggaactgt tcaagtgggt aatggagtta ctcctgtaga gtttgaagct
      301 ggtcaagatg gaaaaccatt cacgattcct acaaaaatca cagtaggtga taaagtattt
      361 accgttactg aagtagctag tcaagctttt agttattatc cagatgaaac aggtagaatt
      421 gtctactatc ctagctctat tactatccca tcaagcataa aaaaaataca aaaaaaaggc
      481 ttccatggaa gtaaagctaa aactattatt tttgacaaag gcagtcagct ggagaaaatt
      541 gaagatagag cttttgattt ttctgaatta gaagagattg aattgcctgc atctctagaa
      601 tatattggaa caagtgcatt ttcttttagt caaaaattga aaaagctaac cttttcctca
      661 agttcaaaat tagaattaat atcacatgag gcttttgcta atttatcaaa tttagagaaa
      721 ctaacattac caaaatcggt taaaacatta ggaagtaatc tatttagact cactactagc
      781 ttaaaacatg ttgatgttga agaaggaaat gaatcgtttg cctcagttga tggtgttttg
      841 ttttcaaaag ataaaaccca attaatttat tatccaagtc aaaaaaatga cgaaagttat
      901 aaaacgccta aggagacaaa agaacttgca tcatattcat ttaataaaaa ttcttacttg
      961 aaaaaactcg aattgaatga aggtttagaa aaaatcggta cttttgcatt tgcagatgcg
     1021 attaaacttg aagaaattag cttaccaaat agtttagaaa ctattgaacg tttagccttt
     1081 tacggtaatt tagaattaaa agaacttata ttaccagata atgttaaaaa ttttggtaaa
     1141 cacgttatga acggtttacc aaaattaaaa agtttaacaa ttggtaataa tatcaactca
     1201 ttgccgtcct tcttcctaag tggcgtctta gattcattaa aggaaattta tattaagaat
     1261 aaaagtacag agttttctgt gaaaaaagat acatttgcaa ttcctgaaac tgttaagttc
     1321 tatgtaacat cagaacatat aaaagatgtt cttaaatcaa atttatctac tagtaatgat
     1381 atcattgttg aaaaagtaga taatataaaa caagaaactg atgtagctaa acctaaaaag
     1441 aattctaatc agggagtag
//
LOCUS       DAVMBH010000097         1426 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVMBH010000097 DAVMBH010000000
VERSION     DAVMBH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.097"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..>1426
                     /gene="lanM"
                     /locus_tag="VYP30_002088"
     CDS             <1..>1426
                     /gene="lanM"
                     /locus_tag="VYP30_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEV1808987.1"
                     /translation="IYIEKIYELFSNTVGRFIPRATLYYSQLLRISLSPEFTQKHFER
                     KMLLRRLYIGSENSETMLIDSEFKDLLEADIPYFSFIIGDNKIFDSKGVEVKGVNLTN
                     FKEDFNSKISTFCDEDLKEQIGYIKDSFISRKNQSDSNDIKFQTYYNKLKPELWLSTA
                     TKIGDLIIDNSIEGVNEYGRKDLAWISVTMQGFEEDVWLPSVLTNDLYSGNAGISLFL
                     INLWNITGKKRFLEYAKKSVETSKVLLGNKYIHSNHLVGAFTGVGGMIYSLAEIAHLT
                     GDVKNKNFIKKSILSLDELILRDTSNDLISGNTGLLAVILKLVNSDSYYNTPDIKYVI
                     SKIVQKILHESKFVDGLRFWECMPNRNYVGFSHGNAGIHSYLFKAMKYLGDSRAEEIL
                     QESLNYEKKCFSSHKNDWYKSKDEKQISYTWCHGSPGILLSKLLLLSSGYNFDNLDND
                     IRLSIENTKAYGFGNNPTYCHGDLG"
BASE COUNT          522 a          155 c          259 g          490 t
ORIGIN      
        1 gatatatatt gaaaaaatat atgagctttt tagtaacaca gttggaagat ttataccaag
       61 ggctacttta tactattcac aattgttaag gatatcacta agcccagaat ttactcagaa
      121 gcattttgag agaaagatgt tacttagaag attatatata ggaagcgaaa attctgagac
      181 aatgttgatt gattcagaat ttaaagattt actagaagca gatattcctt atttttcttt
      241 tattatcggt gataataaaa tatttgattc taaaggggta gaagtaaaag gcgtaaattt
      301 aaccaatttt aaagaagatt ttaacagtaa gatctctact ttttgtgatg aagatttaaa
      361 agaacagatt ggctatatca aggattcttt tataagtaga aaaaatcaat ctgacagcaa
      421 tgacattaaa tttcaaacat attataataa attaaaacca gaattatggt tgtctactgc
      481 tactaaaatt ggagatttga ttattgataa ttcaattgaa ggagttaatg agtacggtcg
      541 aaaagatttg gcctggatta gtgtaacaat gcagggtttt gaagaggatg tttggttacc
      601 ttctgtttta acaaatgatt tgtatagtgg gaatgcagga atttcgttat ttttaatcaa
      661 tttatggaac ataacaggta agaaaagatt tttagagtat gccaagaaat ctgttgaaac
      721 ctcaaaggta ttattgggaa ataagtacat tcactctaat catttagtag gggcttttac
      781 aggtgtagga gggatgatat attcacttgc tgaaattgct catctcactg gagatgtaaa
      841 aaataaaaat tttattaaaa aatctatctt aagtttagat gaactaattt taagggatac
      901 ttcaaatgat ttaattagtg ggaatacagg gctattggct gtaattttaa aacttgttaa
      961 ttcagattca tattacaaca cacctgatat taaatatgtt atttccaaaa tagttcaaaa
     1021 aatattacat gaatcaaagt ttgtagacgg gttaaggttt tgggaatgta tgccaaatag
     1081 aaattatgtt ggtttttctc acggaaatgc aggtatccat tcttatttat ttaaggcaat
     1141 gaaatatttg ggagatagtc gtgcagagga aattttgcaa gaatcattga actatgaaaa
     1201 aaaatgcttc tcttctcata aaaatgattg gtataaatct aaagatgaaa aacaaatatc
     1261 ttatacgtgg tgtcatggat cacctgggat acttttaagt aaattattat tgctttcttc
     1321 aggatataat tttgataatt tagataatga cattagacta agtattgaga acactaaagc
     1381 ttatggattt gggaataatc ctacatattg tcacggtgat ttagga
//
LOCUS       DAVMBH010000098         1265 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVMBH010000098 DAVMBH010000000
VERSION     DAVMBH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.098"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1..657
                     /locus_tag="VYP30_002089"
                     /pseudo
     CDS             1..657
                     /locus_tag="VYP30_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            774..>1265
                     /locus_tag="VYP30_002090"
     CDS             774..>1265
                     /locus_tag="VYP30_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1808988.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKG"
BASE COUNT          443 a          250 c          213 g          359 t
ORIGIN      
        1 ccatttatgg ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtaaaag
       61 gaacaaaacc aagaaaagtt gatagagata gacttaaaaa ctatcttact gataatccag
      121 acgcttattt gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg
      181 cgctcaaagc tatgggctac actcgaaaaa aagaaccaca cctactatga acaagaccca
      241 gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag
      301 attgacgaaa caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt
      361 cagttaataa gaggcaaagt atctggaaga agatatcaga ggatttcttt ggttgcaggt
      421 ctaacaaatg gtgagttaat cgttccaatg acttacgaag agatgatgac gagcgacttt
      481 tttgaagtat ggtttcagaa gtttttctta ccaacattaa ccacaccatc ggttattatt
      541 atggataatg taagattcca tagaatgggg aagctagaac tcttgtgtga agagtttggg
      601 cataaacttt tacctcttcc tccctactca cctgagtaca atcctattga ggctctataa
      661 tatttgtagt gggtaacccc cctatggata ttatagagcc tattttattg tagaaaaaag
      721 tcccataaga tctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac
      781 aattacattt tatcacaaaa ttactagaca ttaaagaccc taatatccag attttagaca
      841 tcatcaataa ggatacacac aaggaaatca tcgccaaact ggactacgac gccccatctt
      901 gccctgagtg cggaaaccaa ttgaagaaat atgactttca aaaaccgtct aagatccctt
      961 acctcgaaac aactggtatg ccttctagaa ttctccttag aaaacgccgt ttcaagtgct
     1021 atcactgttc aaaaatgatg gtcgctgaaa cttctatcgt caagaagaat caccaaatcc
     1081 ctcgtatcat caaccaaaaa attgctcaaa agttaattga aaagatttct atgactgata
     1141 ttgcccatca gctttccatc tcaacttcaa ctgtcattcg aaagctcaat gacttccact
     1201 ttaaacatga tttttcttgt cttcctgaga ttatgtcttg ggatgagtat gcttttacaa
     1261 aagga
//
LOCUS       DAVMBH010000099         1150 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVMBH010000099 DAVMBH010000000
VERSION     DAVMBH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.099"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(186..257)
                     /gene="shp3"
                     /locus_tag="VYP30_002091"
     CDS             complement(186..257)
                     /gene="shp3"
                     /locus_tag="VYP30_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone SHP3"
                     /protein_id="HEV1808989.1"
                     /translation="MKKISKFLPILVLVMDIIIIVGG"
     gene            337..>1150
                     /locus_tag="VYP30_002092"
     CDS             337..>1150
                     /locus_tag="VYP30_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1808990.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISHFERGESEIS
                     CIRLINILDKLHITLDEFLVLYNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKVEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGEDKLKL"
BASE COUNT          412 a          198 c          149 g          391 t
ORIGIN      
        1 aaatttaaaa gtttctcgat ataattctct cctaaatgct ttgttaactc cttttcaaac
       61 gtttctaaac tatactccgg aaaataattt aaccaataat taatcatact atctttcatc
      121 gtatcctcca accagtacta agtctttaga tgatatctaa agacttaggt gtacacctaa
      181 gcatcttacc caccaacaat gatgataata tccatcacca aaaccaaaat cggtaaaaat
      241 tttgaaattt tcttcatact tggacttcct ttccgttttt atttattgta caataaataa
      301 aaacggattt aatttttgtt gggaaaatgg gaaattatga aatcaaaact tggcatcaca
      361 cttagaaaag ttcgtaaagg aaaacaaatt agtctatgct ctgtagcaga tgaacatctt
      421 tcaaaatcac aaatatctca ttttgaacgt ggggagtcag agatatcttg tattcgacta
      481 atcaatattt tagacaaatt acatattact ttggatgagt tccttgtttt atacaatgac
      541 gactatacca gttccgaatc atttgctaat ctagtacagt acattcgtaa gcaatattca
      601 tcacaaagta tcaataatat agcatgtcta ctttctgata cttctgatta cactctaaat
      661 tcttttgaga aaacaatggt aaaatctatt ttacacacaa tggattcgaa catcattcca
      721 tcagatgaag agcttcttca tctgacagac tatcttttca aagttgaaaa atggggctat
      781 tatgaaatca ttttattagg taactgtgta cgcacaatta actacaactc ctacttctta
      841 ttaactaaag agatgttaaa taactatatt tactcatctc tgaataaaac taataagcag
      901 attgtctctc agcttgctat taattgcttc attctaagca ttgataagga agaattttct
      961 aattgctcct atttaattag taagataaag acattgttgg acaatgaact aaacttttat
     1021 gaacaaacag tttttctcta tgcaactggt tactttgaat ttaaacgttg ccaatcaacc
     1081 agtggaattg aaaaaatgaa acaagccata caagtcttcg atattttagg agaagataag
     1141 ttaaaattac
//
LOCUS       DAVMBH010000100         1104 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVMBH010000100 DAVMBH010000000
VERSION     DAVMBH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.100"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            267..923
                     /locus_tag="VYP30_002093"
     CDS             267..923
                     /locus_tag="VYP30_002093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808991.1"
                     /translation="MNQVNVLQLNLMIVIAMIAVWKQYGIKILFYNGAFIFCLMLALI
                     SKRAYLHYLIVLIPLFIPYISVAINKFMNKSSLLYFLIFTIGLVFIYWGPIYGIKDRV
                     TNRSIDYSVKEKEVADYIHQHTNEQDRIYSHSLNGIIYLYSERLSSTKFFFVPSLKDE
                     TPIIDSFKESFKMNPPKYIVFNSKWDYGRLTDSFIKELIQKNYHEEKQIDTMKIYQIN
                     "
BASE COUNT          390 a          130 c          169 g          415 t
ORIGIN      
        1 tgtttactaa ggcaaatatg ataggaattt ggttaatttt ttcgttacta gttacaataa
       61 aacttattta tcaaaaacaa ttctccatat tcttaaagta tattgctctc tttataactg
      121 gaagtgcttt atttattgtc ccattgtgtt gttttttatg gtttcaagga tcactaaaag
      181 aaatgttcta tcagtcagta gttatgaatt ttatttattc caaagaaagt ggctatttga
      241 ctgttatgga aatgataaaa tagtacatga atcaagttaa tgttttacaa ttaaacctca
      301 tgatagttat tgctatgatt gcagtttgga aacaatatgg tataaaaata ttgttttaca
      361 atggtgcttt tattttctgt ttgatgttag ctttaatttc taaaagagct tatttgcatt
      421 acctgattgt ccttatccct ttgtttattc cttatattag tgtagctata aataaattca
      481 tgaataaaag ttctctacta tattttttaa tatttacaat aggcttagtg tttatttatt
      541 ggggacctat ctatggaata aaagatcgag tgacgaatcg ttcaattgat tattctgtaa
      601 aggaaaaaga agttgccgac tatatacatc aacatacaaa tgagcaagat agaatatata
      661 gtcacagcct caatgggatt atttatcttt atagtgagag gttatctagt acaaaattct
      721 tctttgttcc gtctttaaaa gatgagactc caattattga ttctttcaaa gaatcattta
      781 aaatgaatcc tcctaagtac attgttttta attctaagtg ggattatggt agattgacgg
      841 actcctttat aaaagaactt attcaaaaaa actatcatga ggaaaaacaa atcgatacaa
      901 tgaaaatata tcagataaac taggagaaaa aatgaaattt tttaactcaa acagattaat
      961 tgatgtttta aaaatttata gtaaagataa aaagtgtttt gcagaagctg aaattataaa
     1021 ataacgattg cttaagtatt catatgattt cccagagaac tttgaaaatc atatgaatga
     1081 tgtattttag actgggagga tttt
//
LOCUS       DAVMBH010000101          981 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVMBH010000101 DAVMBH010000000
VERSION     DAVMBH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.101"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            106..288
                     /locus_tag="VYP30_002094"
     CDS             106..288
                     /locus_tag="VYP30_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1808992.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            298..663
                     /locus_tag="VYP30_002095"
     CDS             298..663
                     /locus_tag="VYP30_002095"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1808993.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            660..>981
                     /locus_tag="VYP30_002096"
     CDS             660..>981
                     /locus_tag="VYP30_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1808994.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEI"
BASE COUNT          406 a          121 c          164 g          290 t
ORIGIN      
        1 ataacaagag gatagaaatg accgaattag aaagaaaaaa tcgaaaaatt agctaagaaa
       61 tattctgata acttaaacat caaagttcaa gagagagttc gtgaaatggc aaatgataat
      121 aagagccatt atttgatata cagagtttta ggtatttcat ttgaagaagg agaaaatatc
      181 gatttgtatc aaaataaagg tcgtttttta tacaaatatg ctggttcatt tttagaagaa
      241 gctgcagtac tatcctttaa cgaaaaattt ggtacagaaa atacttaaaa agttaacatt
      301 cctaattctg aaagtacaaa acctaagact tttgaaattg attgtttagt cggagaaaaa
      361 cacgcatacg aaataaaatg gtgggatgca actacagatg gagaccatat aactaaagaa
      421 cacactagaa taaaagttat tcataacaaa ggatatatac caattcggtt aatgttctac
      481 tatccaaata gaactcaagc tataaaaatt cagcaaactt tagaaacatt gtataacggt
      541 attggaggga aatattatta tggagattct gcctgggaac atttaagagc agtgaccggt
      601 attgatttac ttagtattct aacagatatt gcaaataaaa aaacaggggt aaaatcaaaa
      661 tgacagtatt aaaaggagat aacttagaaa tattaaaaac tattgaatcc tcaagtattg
      721 atttaatcta tatggaccct cctttcttta cacagaaaac ccaaaaatta tctaataaca
      781 aaaatattat gtattcattc gaagatacgt ggacttcgat tgaggattac aaagaatttt
      841 tgtctgtaag attagaagaa tgcaaaagag tgctaaaaaa tagtggcagt attttcgttc
      901 attgtgataa aattgcaaat catcatatta gattaatttt agataatatc tttggagcag
      961 atatgtttca aagcgaaatt a
//
LOCUS       DAVMBH010000102          881 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVMBH010000102 DAVMBH010000000
VERSION     DAVMBH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.102"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            322..534
                     /locus_tag="VYP30_002097"
     CDS             322..534
                     /locus_tag="VYP30_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1808995.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASIVVIDV"
     gene            592..>881
                     /locus_tag="VYP30_002098"
     CDS             592..>881
                     /locus_tag="VYP30_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV1808996.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIV"
BASE COUNT          342 a           81 c          154 g          304 t
ORIGIN      
        1 acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc tagtttcaat
       61 atactatatt atcgcttacc aacatttgct tttatatttg ctaaactttc agaaaaaaag
      121 ttggagtata tgatgctagg tgactgcgtc atgttagtaa acgaaatgga aataacggat
      181 catagagtag ataacttatt tgaaaaaggg aaaaatgaga taaaagatcc aattggtaca
      241 aatagtgttt taaataaaaa aattatttta caaaaaatca gaaaattatc taatcaaccg
      301 agtgggtact ggataggttc gttggatgag agatttttag accatgctat tattaatcaa
      361 atagatgtta ctagtgaaca aattgtttta atgagcgatg gcttttatga attctatcaa
      421 aataatcaaa ataaaacttt tgaagagtta attaagatga gatttaattc ttctgctatt
      481 gatccaatct atggaaagaa agatgatgca agtattgtag ttattgatgt ttgatatatt
      541 gtttaaaata ttaattgtta ctattgaact ttgttaagaa gaggtaccta aatgttaagg
      601 ttatatttag aaaatgaaat tatagaatta tcaaataatt tagagaccat ttgggtatct
      661 gtgcttgata aatatgagaa gttatttgaa tatttatcaa atgaagaacg aatagaattg
      721 attaaagaag atttaatcat aaatgagtca gttctaaatg ttgataaaaa aggatatgag
      781 ttaatttgtt tacaacatcc cgtttcatat gacttaagaa gaattattag tgtaataaaa
      841 atatcaactg acattgaacg tattggggat agaattgttg a
//
LOCUS       DAVMBH010000103          858 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVMBH010000103 DAVMBH010000000
VERSION     DAVMBH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..858
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.103"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..855)
                     /locus_tag="VYP30_002099"
     CDS             complement(<1..855)
                     /locus_tag="VYP30_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1808997.1"
                     /translation="MPTHNRYESLIRAVKSCLHQSYKNIEVIIIDDNYSNVNLRNKII
                     HQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDEYMPDRILKLMACF
                     KKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLE
                     LINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADE
                     EYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAREEKIFNEF
                     LFLKYMLLY"
BASE COUNT          280 a          154 c           86 g          338 t
ORIGIN      
        1 atataataac atgtatttca aaaaaagaaa ttcgttaaaa attttttctt ctcttgcctt
       61 cttgattact tttaaagcct tgcatttgtc tcctattaat agtaaccgct ttatgtttaa
      121 agaataatat ttctttgtaa ccaatattct ctcgttgaaa ctcaataaat taaaatattt
      181 cctacagtaa ttataatatt cttcatctgc attaattgtt ttttgtgtca ctccagtgat
      241 accgttttct ttactgtgag cgtagtaatt caccaagaat tctcgcacta tatcaatttg
      301 gtatccttga gcaagtagtt ttaataaaac aacaccgtcc tgatgtgaat ctattttctc
      361 aaaaccatta attaattcta gcacctcttt tttacacaac caaaatgacg tacctgctat
      421 attgtgaacc atttgaacaa acaagggatt tccaacaaaa tcggtcttct cctcttctcg
      481 tgtaccattt ggataaatta ttattccata actataaact aaagctaaat tcttcattct
      541 actcttttta aaacaagcca tcaactttaa aattcgatct ggcatatatt catcatcatc
      601 gtctaaaaat gatatatact tacctctaga attttttata cctatgtttc tggcattagt
      661 tgcacctaaa tcttcattac ttaaaattaa cttaattcta tgattggtat agccaaattg
      721 atggataatt ttatttctta aatttacatt actataatta tcatcaataa ttataacttc
      781 gatattttta taactttgat gtaaacaact tttcacagct ctaatcagag attcatacct
      841 attatgtgtt ggtattat
//
LOCUS       DAVMBH010000104          843 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVMBH010000104 DAVMBH010000000
VERSION     DAVMBH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.104"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..>843
                     /gene="phtD"
                     /locus_tag="VYP30_002100"
     CDS             <1..>843
                     /gene="phtD"
                     /locus_tag="VYP30_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1808998.1"
                     /translation="AQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQ
                     GENISSLLRELYAKPLSERHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLS
                     PLEEKLARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKL
                     VKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLP
                     SSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAF
                     LAPIR"
BASE COUNT          263 a          194 c          164 g          222 t
ORIGIN      
        1 gcccaagcct attggaatgg gaagcaggga tctcgtcctt cttcaagttc tagtcataat
       61 gcaaatccag ctcaaccaag attgtcagag aaccacaatc tgactgtcac tccaacttat
      121 catcaaaatc aaggggaaaa catttcaagc cttttacgtg aattgtatgc taaaccctta
      181 tcagaacgcc atgtagaatc tgatggcctt attttcgacc cagcgcaaat cacaagtcga
      241 accgccaatg gtgttgctgt accgcacgga gaccattatc actttattcc ttattcacaa
      301 ctgtcacctt tggaagaaaa attggctcgt attattcccc ttcgttatcg ttcaaaccat
      361 tgggtaccag attcaagacc agaacaacca agtccacaat cgactccgga acctagtcca
      421 agtccgcaac ctgcaccaaa tcctcaacca gctccaagca atccaattga tgagaaattg
      481 gtcaaagaag ctgttcgaaa agtaggcgat ggttatgtct ttgaggagaa tggagtttct
      541 cgttatatcc cagccaagga tctttcagca gaaacagcag caggcattga tagcaaactg
      601 gccaagcagg aaagtttatc tcataagcta ggaactaaga aaactgacct cccatctagt
      661 gatcgagaat tttacaataa ggcttatgac ttactagcaa gaattcacca agatttactt
      721 gataataaag gtcgacaagt tgattttgag gctttggata acctgttgga acgactcaag
      781 gatgtctcaa gtgataaagt caagttagtg gatgatattc ttgccttctt agctccgatt
      841 cgt
//
LOCUS       DAVMBH010000105          761 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVMBH010000105 DAVMBH010000000
VERSION     DAVMBH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.105"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            complement(<1..>761)
                     /locus_tag="VYP30_002101"
     CDS             complement(<1..>761)
                     /locus_tag="VYP30_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4135 domain-containing protein"
                     /protein_id="HEV1808999.1"
                     /translation="YLEIIQQFQEQYVKILELFQCKTDSKVLISKIELGNGDSHKKNK
                     SVSKIFLSSGNTIIYKPRSLNIEKSFEKMMEFLRDQNAILDYKLPNIISTEKYGFCEY
                     IDTEECMNDLDVKGFYQRIGELLGILYSLNSVDFHYENIIAKGAYPVPIDLETLIHPQ
                     IVDRNNDLSAFKKASKKFESSVITTGLLPIFLKGNEVGGVSMNSEQISTFKTDYIKDT
                     NSDNIHIEREYYVISPKNNNPIINGKIVDAKDYIF"
BASE COUNT          252 a          127 c           87 g          295 t
ORIGIN      
        1 tcaaaaatat agtctttggc atctacaatc ttaccattga taataggatt gttgttttta
       61 ggagaaatga cataatactc tctctcaata tgaatattat cgctgttagt atccttgata
      121 tagtcagttt taaaggttga tatttgctca ctattcatac taacaccacc aacttcattt
      181 ccttttaaaa aaatgggtaa aagccctgta gttattactg agctttcaaa ttttttagaa
      241 gcttttttga atgctgataa atcattattt ctatccacta tctgaggatg gattaatgtt
      301 tctaaatcaa ttggaactgg ataagctcct ttcgcaataa tgttttcata atgaaaatct
      361 acagaattca aagaataaag tattcccaac aattctccta ttctttgata aaaccccttt
      421 acatccaaat cattcataca ttcttctgta tctatatatt cacaaaatcc atatttttca
      481 gttgaaataa tattaggtag tttataatct aaaatcgcat tttgatctcg taagaattcc
      541 atcatttttt caaacgattt ttcaatatta agcgagcgag gcttatatat tatagtgttt
      601 ccgcttgata aaaaaatttt actcacactc ttattctttt tatgtgaatc accatttccc
      661 aattctattt tagaaatcaa tactttagaa tccgttttac actgaaatag ttcaagaatt
      721 ttcacatatt gctcttgaaa ttgttgaata atttctaaat a
//
LOCUS       DAVMBH010000106          759 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVMBH010000106 DAVMBH010000000
VERSION     DAVMBH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.106"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..448
                     /locus_tag="VYP30_002102"
     CDS             <1..448
                     /locus_tag="VYP30_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1809000.1"
                     /translation="LVFCLEADNQEQLFDQVASLLEEREIVTPTYREALITREKSFPT
                     GLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDKEVEVSLLFFI
                     INNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA"
     gene            486..>759
                     /locus_tag="VYP30_002103"
     CDS             486..>759
                     /locus_tag="VYP30_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1809001.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGSILFRIPAMSAPVFDNI"
BASE COUNT          249 a          138 c          145 g          227 t
ORIGIN      
        1 ccttgtgttt tgcttagaag cggataatca agaacaactc tttgatcagg tagcaagctt
       61 gttggaagaa cgagaaattg tcactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
      121 gtcatttcca actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat
      181 tcctcacaca gatattgttc ataatctagc tgaaaaagtg gtggttgttc gattagaaaa
      241 accagtaact tttcacaata tgatagctcc tgataaggaa gtagaagtat ccctactctt
      301 ctttatcatt aacaattcaa gttcaagtca aacaaatatt ctggctcagt tgatggactt
      361 tttcacagga aatggacatc ttgaagattt atcaaaaatt tccgaaccag aaaaacttta
      421 tgcttacatt gctgaagcaa tcgcttaatc ttgtctatta aaaaataaaa tcggaggaaa
      481 tccaaatgat taaaattctt gctgcctgcg gtgcaggtgt taactcaagt taccaaatta
      541 aaagtgctct agaagaagaa ctttcaaacc gtggttatga tgttcactgt gatgcagtca
      601 tggtgaaaga tgtaaacgaa gaccttatga aaggttacga tatctttaca ccaatcgctg
      661 caacagatct tggttttgaa ccaggtatcc cagttatcga agctgggtca atcttattcc
      721 gtataccagc aatgagcgct ccagtatttg acaatatta
//
LOCUS       DAVMBH010000107          740 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVMBH010000107 DAVMBH010000000
VERSION     DAVMBH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.107"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..>740
                     /locus_tag="VYP30_002104"
     CDS             <1..>740
                     /locus_tag="VYP30_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1809002.1"
                     /translation="VIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLN
                     IITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFH
                     IIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHL
                     TNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPIFQTVFK
                     TFLKNKEKIVNALQLPYSNAKLEATNNL"
BASE COUNT          231 a          154 c          120 g          235 t
ORIGIN      
        1 gtcattcgca agctcaatga ctttcacttt gagcatgatt tttctcggct tccaaagatt
       61 atgtcttggg atgagtatgc cttcactaag ggaaagatga gtttcattgc gcaagatttt
      121 gataatctta atattatcac tgttcttgaa ggcagaacac aagctgtcat ccgaaatcac
      181 tttcttcgct acgatagagc cgttcgttgt caagtgaaaa tcattacgat ggatatgttt
      241 agtccttact atgacttggc taaacagctt tttccgtgtg ctaaaatcgt tctagatcgt
      301 ttccatatta tccaacatct cagccgtgcc atgagtcgtt ttcgtgttca aattatgaat
      361 cagtttgaac gaaaatctca tgaatacaag gctatcaaac gttactggaa actcatccaa
      421 caggatagtc gtaaattgag cgataaacgt ttttatcgcc ctacttttcg catgcactta
      481 acaaataaag aaattcttga caagatttta agctattcag aagacttgaa acaccactat
      541 cagatctatc aactcttact ttttcacttt cagaacaaag accctgagaa atttttcgga
      601 ctcattgagg acaatctgaa gcaggttcat cctatttttc agactgtctt taaaaccttt
      661 ctaaagaaca aagaaaaaat cgtcaacgct cttcaattac cttattccaa cgcaaaattg
      721 gaagcgacca ataatctcat
//
LOCUS       DAVMBH010000108          720 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVMBH010000108 DAVMBH010000000
VERSION     DAVMBH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.108"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            221..391
                     /locus_tag="VYP30_002105"
     CDS             221..391
                     /locus_tag="VYP30_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lichenicidin alpha family lanthipeptide"
                     /protein_id="HEV1809003.1"
                     /translation="MAQKDFPQKINSQLLEEISDNSAVGAGWAQLSFISEALGNKGAV
                     CTGTIECQNNCR"
     gene            414..605
                     /locus_tag="VYP30_002106"
     CDS             414..605
                     /locus_tag="VYP30_002106"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="HEV1809004.1"
                     /translation="MNNKFTGKINELELEQLVGDNQVVGGITPTIIPATISFVGVTFT
                     VTLNAGACPTSGCTKSCNK"
BASE COUNT          262 a           86 c          137 g          235 t
ORIGIN      
        1 atttgatact gttcttgtta aagaatggga taaaaaaaat ttaaaatctt cgaatacata
       61 cggtctaatg gttggtttat cggggtgggg ttactccatg ttatcaaatt atacggatca
      121 ctctttgaat aactttctat ggttagattg atacgtctct tttttcaaaa gcattattct
      181 gggctatata aattaaaatt agttaggaga gaatagttag atggcacaaa aagattttcc
      241 tcaaaaaatt aacagtcagt tattagaaga aattagtgat aacagtgcag ttggagcggg
      301 atgggcgcag cttagtttta taagtgaagc tcttggaaat aaaggtgcag tttgcacagg
      361 tacaattgaa tgtcaaaata attgtagata ataatattta gtggagaaaa ataatgaata
      421 ataaatttac aggaaaaatt aatgaattag aactcgaaca attagttgga gataatcaag
      481 ttgtaggtgg aataacccct actattattc ccgctacaat ttcttttgtg ggtgttacat
      541 ttaccgtaac attaaatgct ggtgcatgtc caacttccgg atgtacaaag agttgcaata
      601 aataattaag taacaacatt tttgacgata tagcccagta taatgctttt gaataggaga
      661 taattatgac agttgaaagt tatttaaata aaattgaaaa atcaattact tcaggtacta
//
LOCUS       DAVMBH010000109          652 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVMBH010000109 DAVMBH010000000
VERSION     DAVMBH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.109"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            1..652
                     /locus_tag="VYP30_002107"
                     /pseudo
     CDS             1..652
                     /locus_tag="VYP30_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="catalyzes the formation of UDP-glucuronate from
                     UDP-glucose; internal stop; incomplete; missing N-terminus
                     and C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
BASE COUNT          235 a           83 c          119 g          215 t
ORIGIN      
        1 ccgacagatt atgatgagaa aattggtagt tttaatacat atgaaatcga acaaacggta
       61 ttgaagattc tgagggtaaa acctaatgga aagattattt gaaagtcaac agttccgatc
      121 ggcttttcaa acaaattaaa aaggctgttt gatacaaaaa atatcatttt tgtccctgaa
      181 tttttgagag aaggttgttc tatatatgat aatttatatc caagtcgcat agttgttgga
      241 gatgagacag ttgaaggaag aaaaattgca gagttgttcc tttcgattag tactcatagt
      301 actgccaata ttaaaaatgt tatgttagtt tctcctactg aagcagaagc aattaagctt
      361 ttttctaaca cattcttagc tctccgtgtt gcttttttta atgaactaga ttcttttgct
      421 gagaggagaa gtttaaatgc tgaagttgta ataaaaggtg tttgtttaga tccaagaatt
      481 ggaaattttt ataataatcc ttcttttgga tttggaggat attgtcttcc caaagatact
      541 aaacaattaa aaaaagaatt tatagaaata aatgccccag tgatagaagc gattgatatt
      601 tcaaacacaa atagaaaaca gttcatagtt aaacaaatat tggaacgaaa gc
//
LOCUS       DAVMBH010000110          563 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVMBH010000110 DAVMBH010000000
VERSION     DAVMBH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.110"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..>563
                     /locus_tag="VYP30_002108"
     CDS             <1..>563
                     /locus_tag="VYP30_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1809005.1"
                     /translation="QDKKESNRVAYIDGDQAGQKAENLTPDEVSKREGINAEQIVIKI
                     TDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEIKGGYVIKVNG
                     KYYVYLKDAAHADNIRTKEEIKRQKQERSHNHNSRADNAVAAARAQGRYTTDDGYIFN
                     ASDIIEDTGDAYIVPHGDHYHYIPKSD"
BASE COUNT          188 a          100 c          129 g          146 t
ORIGIN      
        1 caggataaga aagagtctaa tcgagttgct tatatagatg gtgatcaggc tggtcaaaag
       61 gcagaaaact tgacaccaga tgaagtcagt aagagggagg ggatcaacgc cgaacaaatt
      121 gttatcaaga ttacggatca aggttatgtg acctctcatg gagaccatta tcattactat
      181 aatggcaagg ttccttatga tgccatcatc agtgaagagc tcctcatgaa agatccgaat
      241 tatcagttga aggattcaga cattgtcaat gaaatcaagg gtggttatgt cattaaggta
      301 aacggtaaat actatgttta ccttaaggat gcagctcatg cggataatat tcggacaaaa
      361 gaagagatta aacgtcagaa gcaggaacgc agtcataatc acaactcaag agcagataat
      421 gctgttgctg cagccagagc ccaaggacgt tatacaacgg atgatgggta tatcttcaat
      481 gcttctgata tcattgaaga tactggtgat gcttatatcg ttcctcacgg cgaccattac
      541 cattacattc ctaagagtga ttt
//
LOCUS       DAVMBH010000111          511 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00034048
            SAMN33607217-rid17949323.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVMBH010000111 DAVMBH010000000
VERSION     DAVMBH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607217
            Sequence Read Archive: SRR23725438
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721315.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721315.1
            Genome Coverage       :: 127x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:41:19
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,109
            CDSs (total)                      :: 2,062
            Genes (coding)                    :: 1,935
            CDSs (with protein)               :: 1,935
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 127
            CDSs (without protein)            :: 127
            Pseudo Genes (ambiguous residues) :: 0 of 127
            Pseudo Genes (frameshifted)       :: 59 of 127
            Pseudo Genes (incomplete)         :: 60 of 127
            Pseudo Genes (internal stop)      :: 43 of 127
            Pseudo Genes (multiple problems)  :: 29 of 127
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607217-rid17949323.denovo.111"
                     /strain="AUSMDU00034048"
                     /serotype="23B"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST439"
     gene            <1..>511
                     /locus_tag="VYP30_002109"
     CDS             <1..>511
                     /locus_tag="VYP30_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1809006.1"
                     /translation="DDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHW
                     IKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDR
                     MPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEH
                     PNERPHSDNG"
BASE COUNT          164 a          104 c          118 g          125 t
ORIGIN      
        1 ctgatgatga gattcaagta gccaagttgg caggcaagta cacaacagaa gacggttata
       61 tctttgatcc tcgtgatata accagtgatg agggggatgc ctatgtaact ccacatatga
      121 cccatagcca ctggattaaa aaagatagtt tgtctgaagc tgagagagcg gcagcccagg
      181 cttatgctaa agagaaaggt ttgacgcctc cttcgacaga ccatcaggat tcaggaaata
      241 ctgaggcaaa aggagcagaa gctatctaca accgcgtgaa agcagctaag aaggtgccac
      301 ttgatcgtat gccttacaat cttcaatata ctgtagaagt caaaaacggt agtttaatca
      361 tacctcatta tgaccattac cataacatca aatttgagtg gtttgacgaa ggcctttatg
      421 aggcacctaa ggggtatact cttgaggatc ttttggcgac tgtcaagtac tatgtcgaac
      481 atccaaacga acgtccgcat tcagataatg g
//
